|
Name |
Accession |
Description |
Interval |
E-value |
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
1-395 |
5.11e-178 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 502.72 E-value: 5.11e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 1 MRKGALLRFFVVIFAIIGIFACTVGWLAGHIRQGLDLQGGTHIVMQA--------EDTDQNKVTPEAITQVINIMQKRVN 72
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSLVAPNGPAKPIKLGLDLQGGVHLLLEVdtdaaldeDGDGIREVTEEALDQAIEILRNRVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 73 EMGLTEPIIQREGSNRIIIELPGEKDPQKAIDTIGKTAVLQFKDE---------------------------EGNVRLTG 125
Cdd:COG0342 81 ELGVSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVddsadaqaavpagsellpcrdgqpyllLGPVVLTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 126 EDLKDAKEQL-GQNKQPLVSLKFSDEGGKKFADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDL 204
Cdd:COG0342 161 DDLTDASAGFdQQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGEVISAPVIQEPITGGSAQITGSFTVEEAQDL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 205 AILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHAT 284
Cdd:COG0342 241 ALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 285 LTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALT 364
Cdd:COG0342 321 LTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVT 400
|
410 420 430
....*....|....*....|....*....|.
gi 2318961056 365 LGLGVAVSMFTAITVSRTLLMLLIDANWIHN 395
Cdd:COG0342 401 LILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-387 |
2.12e-172 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 489.74 E-value: 2.12e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 8 RFFVVIFAIIGIFAC-----------TVGWL----AGHIRQGLDLQGGTHIVMQAE------------------------ 48
Cdd:PRK05812 3 YLLILLVLLIGLLYAlpnlrgalapaTPEWLpalgAKPMKLGLDLRGGVHFLLEVDmddalkkrlesladdlrsllrekk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 49 ------------------------------DTDQNKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKD 98
Cdd:PRK05812 83 iryggveitfrdaedrdkaiallrklssltEAELKEITEEALEQAIEIIRNRVNELGVAEPVIQRQGADRIVVELPGVQD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 99 PQKAIDTIGKTAVLQFKDEEgnVRLTGEDLKDAKEQLGQNKQPLVSLKFSDEGGKKFADLTAANVGRHIGIYLDGEMLTN 178
Cdd:PRK05812 163 TARAKEILGKTATLEFRLVP--VILTGDDITDASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 179 PVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRI 258
Cdd:PRK05812 241 PVIQSAITGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 259 SGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFD 338
Cdd:PRK05812 321 FGLIANIALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2318961056 339 ANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:PRK05812 401 SNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLL 449
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
34-384 |
9.93e-135 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 391.65 E-value: 9.93e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 34 GLDLQGGTHIVMQAE----------DTDQNKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKDPQKAI 103
Cdd:TIGR01129 2 GLDLRGGARVLLEVDmstavvlklsEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 104 DTIGKTAVLQFK----------------DEEGNVR------------------LTGEDLKDAKEQLGQ-NKQPLVSLKFS 148
Cdd:TIGR01129 82 DILGGTATLEFRlvddestspddalagnVPAGSELldsrsgdpkyyllkkspvLTGDHITDATSSVDQrSGQPVVSFSLD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 149 DEGGKKFADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPS 228
Cdd:TIGR01129 162 SEGARIFGDFTQANIGKRLAIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEERTIGPS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 229 LGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIF 308
Cdd:TIGR01129 242 LGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIY 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2318961056 309 ERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLL 384
Cdd:TIGR01129 322 ERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLLL 397
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
176-399 |
5.95e-16 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 80.21 E-value: 5.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 176 LTNPVVNEAITGGAAV--------ITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSL 247
Cdd:NF037998 378 LNNDTINGTKTGAGAGsntnsnqlIVATSTETIARTIEALINQTTSGFTFKVNGISEFNPVVTLLMLIASIIFLLILAIA 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 248 VVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKI-LRLAVQ 326
Cdd:NF037998 458 IMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKRsIEESFK 537
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2318961056 327 AGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLLIDANWIHN-PWWF 399
Cdd:NF037998 538 IANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFKKyPWLL 611
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
243-387 |
3.10e-08 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 54.99 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 243 IGLSLVVLFMLAVYR---ISGFVADTALLVYVLILLGVLYLLHA-----TLTLPSIAGVILsIGMAVDANVLIFERFKEE 314
Cdd:pfam03176 150 VTLVVIFIILLIVYRsvvAALLPLLTVGLSLGAAQGLVAILAHIlgiglSTFALNLLVVLL-IAVGTDYALFLVSRYREE 228
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2318961056 315 IQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:pfam03176 229 LRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALL 301
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
238-407 |
1.50e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 40.77 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 238 IVAFTIGLSLVVLFMLAVYriSGFvadtallvyvlillgvlyllhaTLTLPSIAGVILSIGMAVDANVLIFERFKEEIQE 317
Cdd:NF033617 359 IPAVTVPLSLIGTFAVMYL--FGF----------------------SINLLTLMALVLAIGLVVDDAIVVVENIHRHIEE 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 318 GKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSAT---VKGFALTLGLGVAVSMFTAITVSRTLLMLLIDANWIH 394
Cdd:NF033617 415 GESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTgrlFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANEKP 494
|
170
....*....|...
gi 2318961056 395 NPWWFGGERGYDR 407
Cdd:NF033617 495 GRFARAVDRFFDG 507
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
1-395 |
5.11e-178 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 502.72 E-value: 5.11e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 1 MRKGALLRFFVVIFAIIGIFACTVGWLAGHIRQGLDLQGGTHIVMQA--------EDTDQNKVTPEAITQVINIMQKRVN 72
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSLVAPNGPAKPIKLGLDLQGGVHLLLEVdtdaaldeDGDGIREVTEEALDQAIEILRNRVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 73 EMGLTEPIIQREGSNRIIIELPGEKDPQKAIDTIGKTAVLQFKDE---------------------------EGNVRLTG 125
Cdd:COG0342 81 ELGVSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVddsadaqaavpagsellpcrdgqpyllLGPVVLTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 126 EDLKDAKEQL-GQNKQPLVSLKFSDEGGKKFADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDL 204
Cdd:COG0342 161 DDLTDASAGFdQQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGEVISAPVIQEPITGGSAQITGSFTVEEAQDL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 205 AILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHAT 284
Cdd:COG0342 241 ALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 285 LTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALT 364
Cdd:COG0342 321 LTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVT 400
|
410 420 430
....*....|....*....|....*....|.
gi 2318961056 365 LGLGVAVSMFTAITVSRTLLMLLIDANWIHN 395
Cdd:COG0342 401 LILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-387 |
2.12e-172 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 489.74 E-value: 2.12e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 8 RFFVVIFAIIGIFAC-----------TVGWL----AGHIRQGLDLQGGTHIVMQAE------------------------ 48
Cdd:PRK05812 3 YLLILLVLLIGLLYAlpnlrgalapaTPEWLpalgAKPMKLGLDLRGGVHFLLEVDmddalkkrlesladdlrsllrekk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 49 ------------------------------DTDQNKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKD 98
Cdd:PRK05812 83 iryggveitfrdaedrdkaiallrklssltEAELKEITEEALEQAIEIIRNRVNELGVAEPVIQRQGADRIVVELPGVQD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 99 PQKAIDTIGKTAVLQFKDEEgnVRLTGEDLKDAKEQLGQNKQPLVSLKFSDEGGKKFADLTAANVGRHIGIYLDGEMLTN 178
Cdd:PRK05812 163 TARAKEILGKTATLEFRLVP--VILTGDDITDASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 179 PVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRI 258
Cdd:PRK05812 241 PVIQSAITGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 259 SGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFD 338
Cdd:PRK05812 321 FGLIANIALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2318961056 339 ANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:PRK05812 401 SNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLL 449
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
1-400 |
1.06e-144 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 429.27 E-value: 1.06e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 1 MRKGALLRFFVVIFAIIGIFACTVGWLAGHIRQGLDLQGGTHIVMQAEDTDQNK-VTPEAITQVINIMQKRVNEMGLTEP 79
Cdd:PRK13024 1 MRNKRWVIFFLTLLLLIGIYYASPKFVTKNINLGLDLQGGFEVLLEVSPADKGKkADREALDSTVEVLRNRIDGLGVSEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 80 IIQREGSNRIIIELPGEKDPQKAIDTIGKTAVLQFKD-----------------------EEGNVRLTGEDLKDAKEQLG 136
Cdd:PRK13024 81 NIQREGNNRIRVELPGVQDPERARELLGSTAKLTFRDvtdppppgvggpvvgpdegkdtaVLNPVLLSGDDLTDAGAKFD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 137 QNK--QPLVSLKFSDEGGKKFADLTAANV-----GRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDLAILLR 209
Cdd:PRK13024 161 QDQtnRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRIAIVLDPKVISAPTVNQPINGGSVQISGNFTVEEAKDLANLLN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 210 SGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPS 289
Cdd:PRK13024 241 AGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 290 IAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGV 369
Cdd:PRK13024 321 IAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGI 400
|
410 420 430
....*....|....*....|....*....|.
gi 2318961056 370 AVSMFTAITVSRTLLMLLIDANwIHNPWWFG 400
Cdd:PRK13024 401 LASLFTAVFLTRLLLELLVKRG-DKKPFLFG 430
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
34-384 |
9.93e-135 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 391.65 E-value: 9.93e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 34 GLDLQGGTHIVMQAE----------DTDQNKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKDPQKAI 103
Cdd:TIGR01129 2 GLDLRGGARVLLEVDmstavvlklsEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 104 DTIGKTAVLQFK----------------DEEGNVR------------------LTGEDLKDAKEQLGQ-NKQPLVSLKFS 148
Cdd:TIGR01129 82 DILGGTATLEFRlvddestspddalagnVPAGSELldsrsgdpkyyllkkspvLTGDHITDATSSVDQrSGQPVVSFSLD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 149 DEGGKKFADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPS 228
Cdd:TIGR01129 162 SEGARIFGDFTQANIGKRLAIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEERTIGPS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 229 LGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIF 308
Cdd:TIGR01129 242 LGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIY 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2318961056 309 ERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLL 384
Cdd:TIGR01129 322 ERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLLL 397
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
21-384 |
3.18e-99 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 313.97 E-value: 3.18e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 21 ACTVGWLAGHIRQGLDLQGGTHIVMQAEDTDQ--NKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKD 98
Cdd:PRK14726 122 PVSAGGLGGSSIQELTLQEGGEGQLRLQLTDAgiDYRVSSALTQSIEVVRRRVAELGTTEPLIRRQGDDRIVVQVPGLVD 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 99 PQKAIDTIGKTAVLQFK--DE-------------------------------EGNVRLTGEDLKDAKEQLG-QNKQPLVS 144
Cdd:PRK14726 202 PQRLKNLLNQPAKLSFRlvDSsmpaqealngrppatsevlyslddppvpylvERRAFVSGENLVDAQPVFDpQTNEPVVT 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 145 LKFSDEGGKKFADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRT 224
Cdd:PRK14726 282 FRLDAEGTQRFAQATQQNVGKHFAIVLDGQVISAPVIDEAITGGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERT 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 225 VGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDAN 304
Cdd:PRK14726 362 VGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSN 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 305 VLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLL 384
Cdd:PRK14726 442 VLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLV 521
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
39-386 |
4.30e-87 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 276.18 E-value: 4.30e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 39 GGTHIVMQAEDTDQNKVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKDPQKAIDTIGKTAVLQF---- 114
Cdd:PRK12933 211 DDRGLQLKLSQQEKTKFRNLTVQQNLQIMRSRIEELGITEALVQRQGEHRIRIELPGVQDPAAAKNVIGATASLAFyevk 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 115 ----------KDEEGN-VR------LTGEDLKDAKEQLGQNKQPLVSLKFSDEGGKKFADLTAANVGRHIG-IYLD---- 172
Cdd:PRK12933 291 esgsvnakvlKDKNGRpVYvarrpvLGGEHIVDARASLGEMGMAEVNISLDRAGGKKMSDFSRDNIGKPMAtSYSEysrd 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 173 --GEML-TNPVVNEAIT----GGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGL 245
Cdd:PRK12933 371 eqGKTKqSEEVISVATIqsqlGDRFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGM 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 246 SLVVLFMLAVYRISGFVADTALLV-YVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLA 324
Cdd:PRK12933 451 GITLLFMALWYRRLGWVANVALIAnMVCLFGLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQA 530
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2318961056 325 VQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLML 386
Cdd:PRK12933 531 IDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALINL 592
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
30-393 |
1.14e-61 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 212.17 E-value: 1.14e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 30 HIRQGLDLQGGTHIVMQAEDTDQNKVTPEAitqviNIMQKRVNEMGLTEPIIQREGSNRIIIELPGEKDPQKAIDTIGKT 109
Cdd:PRK13023 44 QVSLGLDLSGGSRLILQVQNAGKTDLETTA-----NIMRQRLEELGYGNPVVEGEGRNQIRVEVPGLYDAQLLKDILTIR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 110 AVLQFKDEEGNVR---------------------------------LTGEDLKDAKEQLG-QNKQPLVSLKFSDEGGKKF 155
Cdd:PRK13023 119 GNLSFRAMDDTMSpddairgtppadseivysfddppvgyllkktpiLTGHDITDAKASISaDDGQPVITLTLDDNGRRRL 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 156 ADLTAANVGRHIGIYLDGEMLTNPVVNEAITGGAAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKD 235
Cdd:PRK13023 199 ADLTAQGNENSFAIVVDNQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYAS 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 236 KSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEI 315
Cdd:PRK13023 279 AAVLAALLAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDR 358
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2318961056 316 QEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLmllidANWI 393
Cdd:PRK13023 359 RKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLI-----AQWV 431
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
11-374 |
6.10e-48 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 168.51 E-value: 6.10e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 11 VVIFAIIGIFACTVG-WLAGHIRQGLDLQGGTHIVMQAEDTdqnkVTPEAITQVINIMQKRVNEMGLTEPIIQREGSNRI 89
Cdd:PRK08343 19 LVLASIVAIFPPGGGpGGFTNLQYGLDLSGGSWIQLKLEGP----VTQETMDLVVEILESRLNALGLKDIKVYPVGDQYI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 90 IIELPGEkDPQKAIDTIGK----TAVLQFKDEEGNVRLTGEDLK--DAKEQLGQNKQPLVSLKFSDEGGKKFADL----- 158
Cdd:PRK08343 95 VVEVPGV-DADTAKEIIEKqgvfEARIQTPGNNNETVLTGDDIEsvGSPSQDPSGGAWGVPFTLSEDGAEKFAEVakgkg 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 159 -TAANVGRHIGIYLDGEMLTNPVVNEAITGG----------AAVITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGP 227
Cdd:PRK08343 174 aTDDPSGHPLDMYLDGELIYAAPLSPDLASGlasgpvvitvGSTGTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSP 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 228 SLGQDSKDKSIVA---FTIGLSLVVLF----------MLA-----VYRISGFVAdtallvyvlillgvlyLLHATLTLPS 289
Cdd:PRK08343 254 SLGEQFKKGSLIAgllALLAVALVVFLryreprialpMVItslseVIIILGFAA----------------LIGWQLDLAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 290 IAGVILSIGMAVDANVLIFErfkEEIQEGKILRLAV-QAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLG 368
Cdd:PRK08343 318 IAGIIAVIGTGVDDLIIITD---EVLHEGKVPSRKVfLSRIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILG 394
|
....*.
gi 2318961056 369 VAVSMF 374
Cdd:PRK08343 395 VLIGVL 400
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
160-389 |
7.96e-47 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 172.35 E-value: 7.96e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 160 AANVGRHIGIYLDGEMLTNPVVNEAITGGAAViTGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIV 239
Cdd:PRK12911 835 SGGRGWRMAVVLDGYVVSDPVLNVPLKDHASV-SGKFSHREVHRLATDLKSGAMSFVPEVLSEEVISPELGKSQRTQGII 913
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 240 AFTIGLSLVVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGK 319
Cdd:PRK12911 914 SVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSR 993
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 320 ILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLLID 389
Cdd:PRK12911 994 SLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFMIWMN 1063
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
222-377 |
6.32e-42 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 146.25 E-value: 6.32e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 222 VRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRISGFVADTALLVY-VLILLGVLYLLHATLTLPSIAGVILSIGMA 300
Cdd:TIGR00916 34 VGTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYS 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2318961056 301 VDANVLIFERFKEEI--QEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAI 377
Cdd:TIGR00916 114 VDDTVVIFDRIREELrkYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
176-399 |
5.95e-16 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 80.21 E-value: 5.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 176 LTNPVVNEAITGGAAV--------ITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAFTIGLSL 247
Cdd:NF037998 378 LNNDTINGTKTGAGAGsntnsnqlIVATSTETIARTIEALINQTTSGFTFKVNGISEFNPVVTLLMLIASIIFLLILAIA 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 248 VVLFMLAVYRISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKI-LRLAVQ 326
Cdd:NF037998 458 IMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKRsIEESFK 537
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2318961056 327 AGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLLIDANWIHN-PWWF 399
Cdd:NF037998 538 IANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFKKyPWLL 611
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
218-387 |
2.71e-09 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 59.09 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 218 SVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRIS-GFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILS 296
Cdd:PRK13024 560 TIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTfSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTI 639
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 297 IGMAVDANVLIFERFKEEIQEGK------ILRLAVQAGFKRAFVTifdaNMTVIITSAILFFLGSATVKGFALTLGLGVA 370
Cdd:PRK13024 640 IGYSINDTVVVFDRIRENLRLYKkkdlreIVNKSINQTLSRTINT----SLTTLLVLLALLIFGGSSLRNFSLALLVGLI 715
|
170
....*....|....*..
gi 2318961056 371 VSMFTAITVSRTLLMLL 387
Cdd:PRK13024 716 VGTYSSIFIAAPLWLDL 732
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
240-387 |
3.91e-09 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 58.62 E-value: 3.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 240 AFTIGLSLVVLfmLAVYRisGFVAD-----TALLVYVLILLGVLYLLHATlTLPSIAGVILS---IGMAVDANVLIFERF 311
Cdd:COG2409 176 LITLPVALVVL--LLVFR--SLVAAllpllTAGLAVGVALGLLALLAAFT-DVSSFAPNLLTmlgLGVGIDYALFLVSRY 250
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2318961056 312 KEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:COG2409 251 REELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTLLPALLALL 326
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
243-387 |
3.10e-08 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 54.99 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 243 IGLSLVVLFMLAVYR---ISGFVADTALLVYVLILLGVLYLLHA-----TLTLPSIAGVILsIGMAVDANVLIFERFKEE 314
Cdd:pfam03176 150 VTLVVIFIILLIVYRsvvAALLPLLTVGLSLGAAQGLVAILAHIlgiglSTFALNLLVVLL-IAVGTDYALFLVSRYREE 228
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2318961056 315 IQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:pfam03176 229 LRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALL 301
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
218-388 |
6.25e-08 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 52.22 E-value: 6.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 218 SVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRIS-GFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILS 296
Cdd:pfam02355 14 EIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRfALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 297 IGMAVDANVLIFERFKEEIQEGK------ILRLAVQAGFKRAFVTIfdanMTVIITSAILFFLGSATVKGFALTLGLGVA 370
Cdd:pfam02355 94 IGYSVNDTVVVFDRVRENLRKKTratlneIMNLSINQTLTRTINTS----LTTLLVVVALFVFGGGSLKDFSLALLVGVI 169
|
170
....*....|....*...
gi 2318961056 371 VSMFTAITVSRTLLMLLI 388
Cdd:pfam02355 170 VGTYSSIFIASPILLDLG 187
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
285-387 |
1.42e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 53.71 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 285 LTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALT 364
Cdd:COG1033 270 LSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIV 349
|
90 100
....*....|....*....|...
gi 2318961056 365 LGLGVAVSMFTAITVSRTLLMLL 387
Cdd:COG1033 350 AAIGVLLAFLTSLTLLPALLSLL 372
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
285-387 |
5.20e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 51.78 E-value: 5.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 285 LTLPSIAgviLSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALT 364
Cdd:COG1033 660 ATAVVAS---IALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLL 736
|
90 100
....*....|....*....|...
gi 2318961056 365 LGLGVAVSMFTAITVSRTLLMLL 387
Cdd:COG1033 737 LALGLLVALLAALLLLPALLLLL 759
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
218-387 |
1.32e-06 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 49.67 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 218 SVLEVRTVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRIS-GFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILS 296
Cdd:COG0341 116 EIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRfAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTI 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 297 IGMAVDANVLIFERFKEEIQEGK------ILRLAVQAGFKRAFVTifdaNMTVIITSAILFFLGSATVKGFALTLGLGVA 370
Cdd:COG0341 196 IGYSLNDTVVVFDRIRENLRKYRkmtlaeIINLSINQTLSRTINT----SLTTLLVVLALLFFGGETLRDFALALLIGII 271
|
170
....*....|....*..
gi 2318961056 371 VSMFTAITVSRTLLMLL 387
Cdd:COG0341 272 VGTYSSIFIASPLLLWL 288
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
242-386 |
4.17e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.07 E-value: 4.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 242 TIGLS--LVVLFMLAVYR--ISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQE 317
Cdd:TIGR00921 198 TMAISgiLVVLVLLLDFKrwWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDI 277
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2318961056 318 GKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLML 386
Cdd:TIGR00921 278 GRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQS 346
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
293-398 |
6.90e-06 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 48.43 E-value: 6.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 293 VILSIGMAVDANVLIFERFKEEIQEGkiLRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVS 372
Cdd:TIGR00833 810 FVLLVALGVDYNMLLVSRIKEESPAG--NRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLTAIAQFGFTVGVGILLD 887
|
90 100
....*....|....*....|....*.
gi 2318961056 373 MFTAITVSRTLLMLLIdANWIhnpWW 398
Cdd:TIGR00833 888 TFIVRSVTVPALTLLL-GRWI---WW 909
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
224-380 |
9.94e-06 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 46.50 E-value: 9.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 224 TVGPSLGQDSKDKSIVAFTIGLSLVVLFMLAVYRIS-GFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVD 302
Cdd:TIGR00966 87 AVGPSVGGELARKAVLALLAALVLILIYITVRFEWRfALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTIIGYSIN 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 303 ANVLIFERFKEEIQEGK------ILRLAVQAGFKRAFVTifdaNMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTA 376
Cdd:TIGR00966 167 DTVVVFDRIRENLRKYTrktfteVINLSINQTLSRTINT----SLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTYSS 242
|
....
gi 2318961056 377 ITVS 380
Cdd:TIGR00966 243 IFIA 246
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
191-385 |
1.38e-04 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 44.22 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 191 VITGQRTLEEAKDLAILLRSGALPVKMSVLEVRTVGPSLGQDSKDKSIVAftIGLSLVVLFMLAVYRISGFVADTALLVY 270
Cdd:PRK13023 534 IIGSQEVGDDAEQTVAVKLRGEFEQDYSFQRVDVVGPTVSEQLSRAGVLA--VILSLIGIFIYVWFRFRWQLALGAVLST 611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 271 ---VLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGK------ILRLAVQAGFKRAFVTIFdanm 341
Cdd:PRK13023 612 lhdVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKsaplpaIIDASINQTLSRTLLTSF---- 687
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2318961056 342 TVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLM 385
Cdd:PRK13023 688 VTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLV 731
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
284-387 |
3.76e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 42.68 E-value: 3.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 284 TLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIItsAILFFLGSAtVKGFA- 362
Cdd:TIGR03480 320 HLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATAA--GFFAFLPTD-YKGVSe 396
|
90 100
....*....|....*....|....*..
gi 2318961056 363 --LTLGLGVAVSMFTAITVSRTLLMLL 387
Cdd:TIGR03480 397 lgIIAGTGMFIALFVTLTVLPALLRLL 423
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
242-386 |
5.37e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 42.13 E-value: 5.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 242 TIGLSLVVLFMLAVYR--ISGFVADTALLVYVLILLGVLYLLHATLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGK 319
Cdd:TIGR00921 574 IAGAILVLMILLAVFRnpIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEHG 653
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2318961056 320 ILRlAVQAGFKRAFVTIFDANMTVIITSAILFFLGSATVKGFALTLGLGVAVSMFTAITVSRTLLML 386
Cdd:TIGR00921 654 PKE-AITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
199-392 |
5.74e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.06 E-value: 5.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 199 EEAKDLAILLRSGALPVKMSVlEVRTVG-PSLGQDSKDKS------IVAFTIGLSLVVLFML------AVYRISGFVADT 265
Cdd:COG2409 477 PEAIDLVDRLRDAAAPALEGA-EVLVGGtTAVNIDISDALaddlplVIPVVLGLIFLLLLLLfrsvvaPLKAVLTNLLSL 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 266 A----LLVYV---LILLGVLYLLHATLTLPSIAGVILsIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFD 338
Cdd:COG2409 556 GaalgVLVLVfqhGWLLLGFTPGPLDSFVPLLLFVIL-FGLGMDYEVFLVSRIREEYDRGGGTREAVIRGLARTGRVITS 634
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2318961056 339 ANMTVIITSAILFFLGSATVKGFALTLGLGVAVsmftAITVSRTLL----MLLI-DANW 392
Cdd:COG2409 635 AALIMAAVFAAFATSPLVFLKQIGFGLAVGVLL----DAFVVRMLLvpalMALLgRWNW 689
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
284-388 |
1.19e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 41.36 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 284 TLTLPSIAGVILSIGMAVDANVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSAT---VKG 360
Cdd:PRK09579 382 SINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTgalFKE 461
|
90 100
....*....|....*....|....*...
gi 2318961056 361 FALTLGLGVAVSMFTAITVSRTLLMLLI 388
Cdd:PRK09579 462 FALTLAGAVIISGIVALTLSPMMCALLL 489
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
238-407 |
1.50e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 40.77 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 238 IVAFTIGLSLVVLFMLAVYriSGFvadtallvyvlillgvlyllhaTLTLPSIAGVILSIGMAVDANVLIFERFKEEIQE 317
Cdd:NF033617 359 IPAVTVPLSLIGTFAVMYL--FGF----------------------SINLLTLMALVLAIGLVVDDAIVVVENIHRHIEE 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 318 GKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFLGSAT---VKGFALTLGLGVAVSMFTAITVSRTLLMLLIDANWIH 394
Cdd:NF033617 415 GESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTgrlFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANEKP 494
|
170
....*....|...
gi 2318961056 395 NPWWFGGERGYDR 407
Cdd:NF033617 495 GRFARAVDRFFDG 507
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
233-384 |
9.19e-03 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 38.41 E-value: 9.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 233 SKDKSIVAFTIGLSLVVLFMLaVYRisGFVADTALLVYVLILLGVLYLLHATLTLPSIAGV---------ILSIGMAVDA 303
Cdd:TIGR00833 172 DKDMNRITATTGIIVLIILLL-VYR--SPITMLVPLVSVGFSVVVAQGIVSLLGIPGLIGVnaqttvlltALVIGAGTDY 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318961056 304 NVLIFERFKEEIQEGKILRLAVQAGFKRAFVTIFDANMTVIITSAILFFlgsATVKGFAlTLGLGVAVSMFTAITVSRTL 383
Cdd:TIGR00833 249 AVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSL---ARLPSFK-TLGVSCAVGVLVALLNAVTL 324
|
.
gi 2318961056 384 L 384
Cdd:TIGR00833 325 T 325
|
|
| |
