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Conserved domains on  [gi|2252437833|gb|USB48646|]
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IncN plasmid KikA protein (plasmid) [Klebsiella pneumoniae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrbM super family cl21715
TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In ...
 1-95 4.66e-07

TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In Comamonas testosteroni T-2, TrbM is derived from the IncP1beta plasmid pTSA, which encodes the widespread genes for p-toluenesulfonate (TSA) degradation. This family also includes MPFK and its functional homolog kikA, which are required for efficient conjugative transfer in IncP-9 plasmids.


The actual alignment was detected with superfamily member PRK13893:

Pssm-ID: 451366  Cd Length: 193  Bit Score: 45.54  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2252437833   1 MKKLLIPLIAAGSLLYIPASHAED---------PCKVIMCMAgklTGdSGGSECNSAEAAFFNIVKKNKhgflpNHTKDA 71
Cdd:PRK13893    2 KKKLLALAALVAALGSTAGTASAQdvltgdtrlACEAILCLS---SG-TRPSECTPSLSRYFSITKRKL-----SDTIKA 72

                          90       100
                  ....*....|....*....|....
gi 2252437833  72 RKAFLNECPDNGEGGSNQSMISQI 95
Cdd:PRK13893   73 RLNFLQLCPVANQTPEMQSLVSAI 96
 
Name Accession Description Interval E-value
PRK13893 PRK13893
conjugal transfer protein TrbM; Provisional
 1-95 4.66e-07

conjugal transfer protein TrbM; Provisional


Pssm-ID: 237548  Cd Length: 193  Bit Score: 45.54  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2252437833   1 MKKLLIPLIAAGSLLYIPASHAED---------PCKVIMCMAgklTGdSGGSECNSAEAAFFNIVKKNKhgflpNHTKDA 71
Cdd:PRK13893    2 KKKLLALAALVAALGSTAGTASAQdvltgdtrlACEAILCLS---SG-TRPSECTPSLSRYFSITKRKL-----SDTIKA 72

                          90       100
                  ....*....|....*....|....
gi 2252437833  72 RKAFLNECPDNGEGGSNQSMISQI 95
Cdd:PRK13893   73 RLNFLQLCPVANQTPEMQSLVSAI 96
TrbM pfam07424
TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In ...
 26-101 1.46e-04

TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In Comamonas testosteroni T-2, TrbM is derived from the IncP1beta plasmid pTSA, which encodes the widespread genes for p-toluenesulfonate (TSA) degradation. This family also includes MPFK and its functional homolog kikA, which are required for efficient conjugative transfer in IncP-9 plasmids.


Pssm-ID: 429457  Cd Length: 153  Bit Score: 38.63  E-value: 1.46e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2252437833  26 CKVIMCMAGKLTGdsggSECNSAEAAFFNIVKKNKhgflpNHTKDARKAFLNECPDNGEGGSNQSMISQIISKYGK 101
Cdd:pfam07424  10 CEAILCLSSSTRP----GECSPSLDRYFSIKKKKW-----SDTVNARRNFLSLCPVAGQTPEMAELVDAISRGAGK 76
 
Name Accession Description Interval E-value
PRK13893 PRK13893
conjugal transfer protein TrbM; Provisional
 1-95 4.66e-07

conjugal transfer protein TrbM; Provisional


Pssm-ID: 237548  Cd Length: 193  Bit Score: 45.54  E-value: 4.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2252437833   1 MKKLLIPLIAAGSLLYIPASHAED---------PCKVIMCMAgklTGdSGGSECNSAEAAFFNIVKKNKhgflpNHTKDA 71
Cdd:PRK13893    2 KKKLLALAALVAALGSTAGTASAQdvltgdtrlACEAILCLS---SG-TRPSECTPSLSRYFSITKRKL-----SDTIKA 72

                          90       100
                  ....*....|....*....|....
gi 2252437833  72 RKAFLNECPDNGEGGSNQSMISQI 95
Cdd:PRK13893   73 RLNFLQLCPVANQTPEMQSLVSAI 96
TrbM pfam07424
TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In ...
 26-101 1.46e-04

TrbM; This family contains the bacterial protein TrbM (approximately 180 residues long). In Comamonas testosteroni T-2, TrbM is derived from the IncP1beta plasmid pTSA, which encodes the widespread genes for p-toluenesulfonate (TSA) degradation. This family also includes MPFK and its functional homolog kikA, which are required for efficient conjugative transfer in IncP-9 plasmids.


Pssm-ID: 429457  Cd Length: 153  Bit Score: 38.63  E-value: 1.46e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2252437833  26 CKVIMCMAGKLTGdsggSECNSAEAAFFNIVKKNKhgflpNHTKDARKAFLNECPDNGEGGSNQSMISQIISKYGK 101
Cdd:pfam07424  10 CEAILCLSSSTRP----GECSPSLDRYFSIKKKKW-----SDTVNARRNFLSLCPVAGQTPEMAELVDAISRGAGK 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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