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Conserved domains on  [gi|2130418495|gb|UEK25004|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Conepatus semistriatus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 3.73e-93

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 268.21  E-value: 3.73e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   1 MMTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  81 EVWVSNKVVLYTFILGVLFEVLVSCYILKEDEIEIVFKFNGAGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 2130418495 161 LLAGVLVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 3.73e-93

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 268.21  E-value: 3.73e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   1 MMTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  81 EVWVSNKVVLYTFILGVLFEVLVSCYILKEDEIEIVFKFNGAGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 2130418495 161 LLAGVLVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 6.18e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 57.13  E-value: 6.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  18 VGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLYTFILGV 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2130418495  98 LFEVLvscyilkedeieIVFKFNGAGDWVIYDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLLAGVLVIMEI 171
Cdd:pfam00499  81 LLLAL------------LLLVLLSASLTPAAAAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 3.73e-93

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 268.21  E-value: 3.73e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   1 MMTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  81 EVWVSNKVVLYTFILGVLFEVLVSCYILKEDEIEIVFKFNGAGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 2130418495 161 LLAGVLVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 2-174 1.93e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 124.10  E-value: 1.93e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   2 MTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  82 VWVSNKVVLYTFILGVLFEVLVSCYILKEDEieivfkfngaGDWVI-YDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYE----------GSWVVvDELKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                         170
                  ....*....|....
gi 2130418495 161 LLAGVLVIMEITRG 174
Cdd:MTH00138  151 LLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 2-174 3.46e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 110.71  E-value: 3.46e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   2 MTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  82 VWVSNKVVLYtfiLGVLFEVLVSCYILKEDEIEIVFKFNGAGDWViydtgdsGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00065   81 AWGSWSVLVY---VLFYLLLLIVGYILFGCNFSLEFLFTNYDTEF-------SVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                         170
                  ....*....|...
gi 2130418495 162 LAGVLVIMEITRG 174
Cdd:MTH00065  151 LLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 2-174 2.48e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 98.28  E-value: 2.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   2 MTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  82 VWVSNKVVLYTFILGVLFEVLVSCYilkedeieIVFKFNGAGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVV--------GGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                         170
                  ....*....|...
gi 2130418495 162 LAGVLVIMEITRG 174
Cdd:MTH00115  153 LLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 2-174 8.27e-18

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 76.18  E-value: 8.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   2 MTYIVFILSVIFVMGFVGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  82 VWVSNKVVLYTFILGVLFEVLVSCYILkedeieivfkfngaGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYG--------------GWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                         170
                  ....*....|...
gi 2130418495 162 LAGVLVIMEITRG 174
Cdd:MTH00214  147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-175 2.84e-13

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 63.77  E-value: 2.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   1 MMTYIVFILsVIFVMGFVGFSSkpSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00045    1 MVFYLFLIL-MLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  81 EVWVSNKVVLYTFILGVLfevlvscyilkedeieIVFKFNGAGDWVIYDTGDSGFFSEeaMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00045   78 SVSNLGEVLVLSLLLSLW----------------VFISFDNFLELSNNNWSLVSLSDL--VGSSELYNSGGLYLLLGGFI 139

                         170
                  ....*....|....*
gi 2130418495 161 LLAGVLVIMEITRGN 175
Cdd:MTH00045  140 LLVALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 6.18e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 57.13  E-value: 6.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495  18 VGFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLYTFILGV 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2130418495  98 LFEVLvscyilkedeieIVFKFNGAGDWVIYDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLLAGVLVIMEI 171
Cdd:pfam00499  81 LLLAL------------LLLVLLSASLTPAAAAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-117 1.41e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 40.26  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130418495   1 MMTYIVFILSVIFVMGFVGFSSkpsPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEqyp 80
Cdd:MTH00152    1 MSLMILLSVCFSLFLLLPLSKQ---PLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPN--- 74

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2130418495  81 EVWVSNKVVLYTFILGVLFEVLVSCYILKEDEIEIVF 117
Cdd:MTH00152   75 PLFGSNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSL 111
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 8-75 5.61e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 38.45  E-value: 5.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2130418495   8 ILSVIFVMGFVgFSSKPSPIYGGLALIVSGGIGCAVVLCFGGSFLGLMVFLIYLGGMLVVFGYTTAMA 75
Cdd:MTH00212    6 LLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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