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Conserved domains on  [gi|1709742315|gb|TVL21435|]
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DNA polymerase III subunit delta' [Shewanella xiamenensis]

Protein Classification

DNA polymerase III subunit( domain architecture ID 11489505)

DNA polymerase III subunit such as delta, delta', gamma, and tau, is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 19-206 1.51e-83

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 250.24  E-value: 1.51e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  19 RQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQ 98
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  99 IRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLI 178
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160

                         170       180
                  ....*....|....*....|....*...
gi 1709742315 179 KNWLIQQCQIQEDVTWCLSVVGGPLKLA 206
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALAGGSPGRA 188
 
Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 19-206 1.51e-83

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 250.24  E-value: 1.51e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  19 RQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQ 98
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  99 IRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLI 178
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160

                         170       180
                  ....*....|....*....|....*...
gi 1709742315 179 KNWLIQQCQIQEDVTWCLSVVGGPLKLA 206
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALAGGSPGRA 188
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
15-210 9.78e-60

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 192.88  E-value: 9.78e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  15 LDAPRQAFLTQLQTQKVPHAQLV----GIdsayGGELLSVFMARAAMCSQPTPAGGCGFCKScQLFDAGNHPDFYQIEAD 90
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLhgppGI----GKTTLALALARDLLCENPEGGKACGQCHS-RLMAAGNHPDLLELNPE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  91 --GHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRL 168
Cdd:COG0470    76 ekSDQIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVI 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1709742315 169 PFVTPSKMLIKNWLIQQCQIQEDVTWCLSVVGGPLKLAESLL 210
Cdd:COG0470   156 RFRPPSEEEALAWLREEGVDEDALEAILRLAGGDPRAAINLL 197
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 13-245 8.18e-50

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 168.34  E-value: 8.18e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWldapRQAFLTQLQTQK-VPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQI---E 88
Cdd:PRK05707    6 PW----QQSLWQQLAGRGrHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLepeE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  89 ADgHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRL 168
Cdd:PRK05707   82 AD-KTIKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 169 PFVTPSKMLIKNWLIQQ---CQIQEDVTWCLSVVGGPLKlAESLLSDGTQPSRYQTLLGFRKDWAQSLSSGHLCASLLTI 245
Cdd:PRK05707  161 ACPLPSNEESLQWLQQAlpeSDERERIELLTLAGGSPLR-ALQLHEQGVREQRARVLDGVKKLLKQQQSASQLAESWLKV 239
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 20-170 2.05e-48

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 159.30  E-value: 2.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQI 99
Cdd:pfam13177   7 QLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSIKIDQI 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:pfam13177  87 RELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRF 157
 
Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 19-206 1.51e-83

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 250.24  E-value: 1.51e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  19 RQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQ 98
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  99 IRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLI 178
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160

                         170       180
                  ....*....|....*....|....*...
gi 1709742315 179 KNWLIQQCQIQEDVTWCLSVVGGPLKLA 206
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALAGGSPGRA 188
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
15-210 9.78e-60

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 192.88  E-value: 9.78e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  15 LDAPRQAFLTQLQTQKVPHAQLV----GIdsayGGELLSVFMARAAMCSQPTPAGGCGFCKScQLFDAGNHPDFYQIEAD 90
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLhgppGI----GKTTLALALARDLLCENPEGGKACGQCHS-RLMAAGNHPDLLELNPE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  91 --GHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRL 168
Cdd:COG0470    76 ekSDQIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVI 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1709742315 169 PFVTPSKMLIKNWLIQQCQIQEDVTWCLSVVGGPLKLAESLL 210
Cdd:COG0470   156 RFRPPSEEEALAWLREEGVDEDALEAILRLAGGDPRAAINLL 197
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 13-245 8.18e-50

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 168.34  E-value: 8.18e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWldapRQAFLTQLQTQK-VPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQI---E 88
Cdd:PRK05707    6 PW----QQSLWQQLAGRGrHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLepeE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  89 ADgHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRL 168
Cdd:PRK05707   82 AD-KTIKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 169 PFVTPSKMLIKNWLIQQ---CQIQEDVTWCLSVVGGPLKlAESLLSDGTQPSRYQTLLGFRKDWAQSLSSGHLCASLLTI 245
Cdd:PRK05707  161 ACPLPSNEESLQWLQQAlpeSDERERIELLTLAGGSPLR-ALQLHEQGVREQRARVLDGVKKLLKQQQSASQLAESWLKV 239
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 20-170 2.05e-48

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 159.30  E-value: 2.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQI 99
Cdd:pfam13177   7 QLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSIKIDQI 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:pfam13177  87 RELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRF 157
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
20-250 5.99e-47

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 161.13  E-value: 5.99e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLV----GIdsayGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIK 95
Cdd:COG2812    20 RTLKNALASGRLAHAYLFtgprGV----GKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNIG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  96 VDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSK 175
Cdd:COG2812    96 VDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPP 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 176 MLIKNWLIQQCQ-----IQEDVtwcLSVV-----GGP---LKLAESLLSDGTQPSRYQTLlgfrkDWAQSLSSGHLcASL 242
Cdd:COG2812   176 EEIAEHLAKIAEregieIEPEA---LALIaraadGSMrdaLSLLDQAIAFGLLDRRELLL-----DLLEALLAGDV-AAL 246


                  ....*...
gi 1709742315 243 LTISEQQI 250
Cdd:COG2812   247 LALAEELA 254
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 13-225 1.20e-45

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 157.59  E-value: 1.20e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWLDAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEA-DG 91
Cdd:PRK06871    5 PWLQPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPiDN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  92 HQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFV 171
Cdd:PRK06871   85 KDIGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWLIH 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1709742315 172 TPSKMLIKNWLIQQCQ--IQEDVTWCLSVVGGPLkLAESLLSDGTQPSRYQTLLGF 225
Cdd:PRK06871  165 PPEEQQALDWLQAQSSaeISEILTALRINYGRPL-LALTFLEQGLLEQRKTFLRQF 219
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 13-185 1.39e-39

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 141.48  E-value: 1.39e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWLDAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCsQPTPAGGCGFCKSCQLFDAGNHPDFYQI--EAD 90
Cdd:PRK06090    6 PWLVPVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLC-QNYQSEACGFCHSCELMQSGNHPDLHVIkpEKE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  91 GHQIKVDQIRElCSRLS-ATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLP 169
Cdd:PRK06090   85 GKSITVEQIRQ-CNRLAqESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWV 163

                         170
                  ....*....|....*.
gi 1709742315 170 FVTPSKMLIKNWLIQQ 185
Cdd:PRK06090  164 VTPPSTAQAMQWLKGQ 179
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 13-255 3.85e-39

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 140.59  E-value: 3.85e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWLDAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQI--EAD 90
Cdd:PRK07993    5 PWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLtpEKG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  91 GHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK07993   85 KSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHYL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 171 VTPSKMLIKNWLIQQCQI-QEDVTWCLSVVGGPLKLAESLLsdgtQPSRYQTLLGFRKDWAQSLSSG------------- 236
Cdd:PRK07993  165 APPPEQYALTWLSREVTMsQDALLAALRLSAGAPGAALALL----QPERWQQREALCQALAYALPSGdwlsllpalnheq 240

                         250       260
                  ....*....|....*....|....
gi 1709742315 237 -----HLCASLLTiseqqiiDALK 255
Cdd:PRK07993  241 aparlHWLATLLM-------DALK 257
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 12-185 1.90e-34

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 128.06  E-value: 1.90e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  12 LPWldapRQAFLTQLQT--QKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPA-GGCGFCKSCQLFDAGNHPDFYQI- 87
Cdd:PRK08699    3 YPW----HQEQWRQIAEhwERRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEIt 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  88 -----EADGH---QIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMA 159
Cdd:PRK08699   79 plsdePENGRkllQIKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLP 158

                         170       180
                  ....*....|....*....|....*.
gi 1709742315 160 TISSRCQRLPFVTPSKMLIKNWLIQQ 185
Cdd:PRK08699  159 TIKSRCRKMVLPAPSHEEALAYLRER 184
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 20-212 1.07e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 123.50  E-value: 1.07e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQI 99
Cdd:PRK08058   16 KMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVAPDGQSIKKDQI 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIK 179
Cdd:PRK08058   96 RYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPLPPESLI 175

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1709742315 180 NWLIQQcQIQEDVTWCLSVVGGPLKLAESLLSD 212
Cdd:PRK08058  176 QRLQEE-GISESLATLLAGLTNSVEEALALSED 207
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 13-222 7.05e-30

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 116.01  E-value: 7.05e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWLDAPRQAfLTQLQtQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAG-GCGFCKSCQLFDAGNHPDFYQI---- 87
Cdd:PRK06964    4 PWQTDDWNR-LQALR-ARLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQPDGePCGTCAACNWFAQGNHPDYRIVrpea 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  88 ------------------------EADGHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGK 143
Cdd:PRK06964   82 laaeapgaadeakeadadeggkktKAPSKEIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPP 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1709742315 144 DTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQcQIQEDVTWCLSVVGGPLKlAESLLSDGTQPSRYQTL 222
Cdd:PRK06964  162 GTVFLLVSARIDRLLPTILSRCRQFPMTVPAPEAAAAWLAAQ-GVADADALLAEAGGAPLA-ALALASDENRPLRDWTL 238
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 53-212 1.02e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 111.16  E-value: 1.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  53 ARAAMCSQPTPaGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQIRELCSRlSATAQQSGR-RVAIIHHSERLNSASA 131
Cdd:PRK07940   57 AAALQCTDPDE-PGCGECRACRTVLAGTHPDVRVVAPEGLSIGVDEVRELVTI-AARRPSTGRwRIVVIEDADRLTERAA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 132 NALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQCQIQEDVT-WCLSVVGGPLKLAESLL 210
Cdd:PRK07940  135 NALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTPSVEAVAEVLVRRDGVDPETArRAARASQGHIGRARRLA 214


                  ..
gi 1709742315 211 SD 212
Cdd:PRK07940  215 TD 216
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 16-168 1.50e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 110.12  E-value: 1.50e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  16 DAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMcSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGH--- 92
Cdd:PRK07471   25 AAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLL-ATPPPGGDGAVPPPTSLAIDPDHPVARRIAAGAHggl 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  93 ----------------QIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPAR 156
Cdd:PRK07471  104 ltlerswnekgkrlrtVITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPAR 183

                         170
                  ....*....|..
gi 1709742315 157 LMATISSRCQRL 168
Cdd:PRK07471  184 LLPTIRSRCRKL 195
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
 76-170 3.57e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 102.67  E-value: 3.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  76 FDAGNHPDFYQIE----------------ADGH------QIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANA 133
Cdd:PRK07399   64 LEEGNHPDLLWVEptyqhqgklitaseaeEAGLkrkappQIRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANA 143

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1709742315 134 LLKTLEEPGKDTLLLLHSdTPARLMATISSRCQRLPF 170
Cdd:PRK07399  144 LLKTLEEPGNGTLILIAP-SPESLLPTIVSRCQIIPF 179
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 23-170 4.08e-23

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 99.14  E-value: 4.08e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  23 LTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGgCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIREL 102
Cdd:PRK14963   27 LAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCSGEDPKP-CGECESCLAVRRGAHPDVLEIDAASNN-SVEDVRDL 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315 103 CSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14963  105 REKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRF 172
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 13-185 4.46e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 96.95  E-value: 4.46e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  13 PWLDAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCgfcKSCQLFDAGNHPDFYQIE---- 88
Cdd:PRK08769    7 PWQQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGPDPAAAQ---RTRQLIAAGTHPDLQLVSfipn 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  89 --ADG--HQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSR 164
Cdd:PRK08769   84 rtGDKlrTEIVIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSR 163

                         170       180
                  ....*....|....*....|.
gi 1709742315 165 CQRLPFVTPSKMLIKNWLIQQ 185
Cdd:PRK08769  164 CQRLEFKLPPAHEALAWLLAQ 184
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 20-166 4.20e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 93.93  E-value: 4.20e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDsaYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQI 99
Cdd:PRK07276   12 QRFQTILEQDRLNHAYLFSGD--FASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQGQVIKTDTI 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQ 166
Cdd:PRK07276   90 RELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQ 156
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 16-187 2.19e-21

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 94.12  E-value: 2.19e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  16 DAPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQiK 95
Cdd:PRK14953   22 EIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDLIEIDAASNR-G 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  96 VDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSK 175
Cdd:PRK14953  101 IDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTK 180

                         170
                  ....*....|..
gi 1709742315 176 MLIKNWLIQQCQ 187
Cdd:PRK14953  181 EQIKEYLKRICN 192
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 20-171 6.51e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 87.17  E-value: 6.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQL------VGIDSAygGELLsvfmARAAMCSQPTPAG-GCGFCKSCQLFDAGNHPDFYQIEADGH 92
Cdd:PRK14950   26 QTLRNAIAEGRVAHAYLftgprgVGKTST--ARIL----AKAVNCTTNDPKGrPCGTCEMCRAIAEGSAVDVIEMDAASH 99

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1709742315  93 QiKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFV 171
Cdd:PRK14950  100 T-SVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQRFDFH 177
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 19-180 3.33e-18

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 84.82  E-value: 3.33e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  19 RQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQ 98
Cdd:PRK14962   23 KKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDVIELDAASNR-GIDE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  99 IRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVT-PSKML 177
Cdd:PRK14962  102 IRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQVIEFRNiSDELI 181


                  ...
gi 1709742315 178 IKN 180
Cdd:PRK14962  182 IKR 184
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
 20-170 7.97e-18

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 82.61  E-value: 7.97e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQL------VGIDSayggelLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHq 93
Cdd:TIGR02397  24 QTLKNAIKNGRIAHAYLfsgprgTGKTS------IARIFAKALNCQNGPDGEPCNECESCKEINSGSSLDVIEIDAASN- 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709742315  94 IKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:TIGR02397  97 NGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPATILSRCQRFDF 173
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 94-170 1.99e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 78.54  E-value: 1.99e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709742315  94 IKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK09112  121 ITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISL 197
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 20-185 2.46e-16

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 79.75  E-value: 2.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQI 99
Cdd:PRK08691   26 KALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDA-ASNTGIDNI 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 100 RELCSRlSATAQQSGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCqrLPFVtpskmlI 178
Cdd:PRK08691  105 REVLEN-AQYAPTAGKyKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRC--LQFV------L 175


                  ....*..
gi 1709742315 179 KNWLIQQ 185
Cdd:PRK08691  176 RNMTAQQ 182
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 67-170 2.96e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 76.14  E-value: 2.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  67 CGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTL 146
Cdd:PRK14954   81 CGECESCRDFDAGTSLNISEFDAASNN-SVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAI 159

                          90       100
                  ....*....|....*....|....
gi 1709742315 147 LLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14954  160 FIFATTELHKIPATIASRCQRFNF 183
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 26-194 1.14e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 74.21  E-value: 1.14e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  26 LQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSR 105
Cdd:PRK14956   34 LKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEIDAASNR-GIENIRELRDN 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 106 LSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQ 185
Cdd:PRK14956  113 VKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKL 192

                         170
                  ....*....|....*
gi 1709742315 186 CQI------QEDVTW 194
Cdd:PRK14956  193 CKIenvqydQEGLFW 207
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 67-220 1.50e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 73.39  E-value: 1.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  67 CGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTL 146
Cdd:PRK14955   81 CGECESCRDFDAGTSLNISEFDAASNN-SVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAI 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 147 LLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQC---QIQEDVTwCLSVVG----GPLKLAESLL--------- 210
Cdd:PRK14955  160 FIFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICeaeGISVDAD-ALQLIGrkaqGSMRDAQSILdqviafsve 238

                         170
                  ....*....|
gi 1709742315 211 SDGTQPSRYQ 220
Cdd:PRK14955  239 SEGEGSIRYD 248
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
58-256 2.71e-14

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 73.46  E-value: 2.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  58 CSQPTPAGgCGFCKSCQLFDAGNHPDFYQIEA---DGhqikVDQIRELCSRlsatAQ----QSGRRVAIIHHSERLNSAS 130
Cdd:PRK14948   67 SDKPTPEP-CGKCELCRAIAAGNALDVIEIDAasnTG----VDNIRELIER----AQfapvQARWKVYVIDECHMLSTAA 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 131 ANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFV-TPSKMLIKN--WLIQQCQIQEDVTwCLSVV-----GGp 202
Cdd:PRK14948  138 FNALLKTLEEPPPRVVFVLATTDPQRVLPTIISRCQRFDFRrIPLEAMVQHlsEIAEKESIEIEPE-ALTLVaqrsqGG- 215

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 203 LKLAES------LLSDGTQPSRYQTLLGfrkdwaqslssghlcasllTISEQQIIDALKV 256
Cdd:PRK14948  216 LRDAESlldqlsLLPGPITPEAVWDLLG-------------------AVPEQDLLNLLKA 256
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 12-167 3.32e-14

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 72.97  E-value: 3.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  12 LPWLDAPRQAFLTQLQTQKVphaqLVGI-------DSAYGGELLS-----------VFMARAAMCSQP----TPAGGCGF 69
Cdd:PRK06645    9 IPFARKYRPSNFAELQGQEV----LVKVlsytilnDRLAGGYLLTgirgvgkttsaRIIAKAVNCSALitenTTIKTCEQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  70 CKSCQLFDAGNHPDFYQIEAdGHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLL 149
Cdd:PRK06645   85 CTNCISFNNHNHPDIIEIDA-ASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIF 163

                         170
                  ....*....|....*...
gi 1709742315 150 HSDTPARLMATISSRCQR 167
Cdd:PRK06645  164 ATTEVQKIPATIISRCQR 181
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
26-165 4.27e-14

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 72.99  E-value: 4.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  26 LQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGG-----CGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIR 100
Cdd:PRK12323   32 LEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEGGitaqpCGQCRACTEIDAGRFVDYIEMDAASNR-GVDEMA 110

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709742315 101 ELCSRlSATAQQSGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK12323  111 QLLDK-AVYAPTAGRfKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRC 175
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 20-165 9.11e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 71.69  E-value: 9.11e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQI 99
Cdd:PRK14958   26 RALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEVDA-ASRTKVEDT 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14958  105 RELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRC 170
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
26-166 1.51e-13

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 70.96  E-value: 1.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  26 LQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAG-GCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCS 104
Cdd:PRK14971   33 IATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLTADGeACNECESCVAFNEQRSYNIHELDAASNN-SVDDIRNLIE 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1709742315 105 RLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQ 166
Cdd:PRK14971  112 QVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQ 173
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 52-187 1.53e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 70.95  E-value: 1.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  52 MARAAMCSQ-PTPAGgCGFCKSCQLFDAGNHPDFyqIEADG-HQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSA 129
Cdd:PRK06647   58 FARCLNCVNgPTPMP-CGECSSCKSIDNDNSLDV--IEIDGaSNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNS 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315 130 SANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQCQ 187
Cdd:PRK06647  135 AFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCL 192
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
24-176 1.80e-13

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 70.68  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  24 TQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFdAGNHP---DFYQIEADGHQiKVDQIR 100
Cdd:PRK14952   27 SALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVAL-APNGPgsiDVVELDAASHG-GVDDTR 104

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315 101 ELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF--VTPSKM 176
Cdd:PRK14952  105 ELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFrlLPPRTM 182
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 26-210 8.40e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 68.65  E-value: 8.40e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  26 LQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGG-CGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCS 104
Cdd:PRK06305   33 LRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTEDQEpCNQCASCKEISSGTSLDVLEIDGASHR-GIEDIRQINE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 105 RLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQR--LPFVTPSKMLIKNWL 182
Cdd:PRK06305  112 TVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKmhLKRIPEETIIDKLAL 191

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1709742315 183 I-QQCQIQEDVTWCLSV---VGGPLKLAESLL 210
Cdd:PRK06305  192 IaKQEGIETSREALLPIaraAQGSLRDAESLY 223
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
20-165 9.83e-13

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 68.54  E-value: 9.83e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQI 99
Cdd:PRK14960   25 RALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNEGRFIDLIEIDA-ASRTKVEDT 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709742315 100 RELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14960  104 RELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRC 169
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 26-182 1.16e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 68.18  E-value: 1.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  26 LQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQIRELCSR 105
Cdd:PRK14957   32 LETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFIDLIEIDA-ASRTGVEETKEILDN 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709742315 106 LSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWL 182
Cdd:PRK14957  111 IQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQADIKDQL 187
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 80-168 1.40e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 66.41  E-value: 1.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  80 NHPDFYQIE------ADGHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDT 153
Cdd:PRK06581   49 NNPDYHFIAretsatSNAKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSR 128

                          90
                  ....*....|....*
gi 1709742315 154 PARLMATISSRCQRL 168
Cdd:PRK06581  129 AASIISTIRSRCFKI 143
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 20-165 1.73e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 67.85  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQI 99
Cdd:PRK14969   26 RALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSGRFVDLIEVDA-ASNTQVDAM 104

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709742315 100 RELCSRlSATAQQSGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14969  105 RELLDN-AQYAPTRGRfKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRC 170
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 56-170 1.76e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 67.50  E-value: 1.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  56 AMC----SQPTPAGgCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASA 131
Cdd:PRK14964   56 SLClncsNGPTSDP-CGTCHNCISIKNSNHPDVIEIDAASNT-SVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAF 133

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1709742315 132 NALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14964  134 NALLKTLEEPAPHVKFILATTEVKKIPVTIISRCQRFDL 172
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 52-170 1.86e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 67.84  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  52 MARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASA 131
Cdd:PRK14965   58 LAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEIDG-ASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAF 136

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1709742315 132 NALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14965  137 NALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDF 175
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 27-170 1.89e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 67.78  E-value: 1.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  27 QTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSRL 106
Cdd:PRK14959   33 QENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDVVEIDGASNR-GIDDAKRLKEAI 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1709742315 107 SATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14959  112 GYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQHFTF 175
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 94-166 2.14e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 66.59  E-value: 2.14e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1709742315  94 IKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQ 166
Cdd:PRK05564   73 IGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQ 145
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 53-170 2.22e-12

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 67.37  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  53 ARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFyqIEADG--HQiKVDQIRELCSRlSATAQQSGR-RVAIIHHSERLNSA 129
Cdd:PRK08451   57 ARALVCEQGPSSTPCDTCIQCQSALENRHIDI--IEMDAasNR-GIDDIRELIEQ-TKYKPSMARfKIFIIDEVHMLTKE 132

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1709742315 130 SANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK08451  133 AFNALLKTLEEPPSYVKFILATTDPLKLPATILSRTQHFRF 173
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 19-170 1.81e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 64.87  E-value: 1.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  19 RQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQ 98
Cdd:PRK05896   25 KKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVELDAASNN-GVDE 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1709742315  99 IRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK05896  104 IRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQRYNF 175
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 58-175 6.38e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 61.77  E-value: 6.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  58 CSQPTpaGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQIRELCSRLSATAQQS-GRRVAIIHHSERLNSASANALLK 136
Cdd:PRK05818   33 CTKAN--GFCKTCESCLKILNGKYNDFYLIFDQKNPIKKEDALSIINKLNRPSVESnGKKIYIIYGIEKLNKQSANSLLK 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1709742315 137 TLEEPGKDTLLLLHSDTPARLMATISSRC---------QRLPFVTPSK 175
Cdd:PRK05818  111 LIEEPPKNTYGIFTTRNENNILNTILSRCvqyvvlskeKKVPFKVESN 158
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 20-165 6.81e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 62.81  E-value: 6.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  20 QAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGG-----CGFCKSCQLFDAGNHPDFYQIEADGHQi 94
Cdd:PRK14951   26 QALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDGQGGitatpCGVCQACRDIDSGRFVDYTELDAASNR- 104

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1709742315  95 KVDQIRELCSRlSATAQQSGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14951  105 GVDEVQQLLEQ-AVYKPVQGRfKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSRC 175
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
 70-171 3.29e-10

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 60.99  E-value: 3.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  70 CKSCQLfDAGNHPDFYQIEADGHQiKVDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLL 149
Cdd:PRK07133   76 CQECIE-NVNNSLDIIEMDAASNN-GVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFIL 153

                          90       100
                  ....*....|....*....|..
gi 1709742315 150 HSDTPARLMATISSRCQRLPFV 171
Cdd:PRK07133  154 ATTEVHKIPLTILSRVQRFNFR 175
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 16-244 6.02e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 59.04  E-value: 6.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  16 DAPRQAFLTQLQTQKVPHAQLV-GID----SAYGGELLSVFMARAAMCSQptpaggcgfCKSCQLFdagnHPDFYQIEAD 90
Cdd:PRK05917    3 SAAWEALIQRVRDQKVPSAIILhGQDlsnlSARAYELASLILKETSPEAA---------YKISQKI----HPDIHEFSPQ 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  91 G----HQIKVDqiRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC- 165
Cdd:PRK05917   70 GkgrlHSIETP--RAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSl 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315 166 ----QRLPFVTPSKMLIkNWLIQQCQIQEDVTWCLSVVGGPLKLAESLLSDGTQPSRYQTLLGFRKDWAQSLSsghLCAS 241
Cdd:PRK05917  148 sihiPMEEKTLVSKEDI-AYLIGYAQGKESVTEVGQIVKGSADTDKQVLRDKTKAMLEVLLQLFRDRFLLALK---VPAS 223


                  ...
gi 1709742315 242 LLT 244
Cdd:PRK05917  224 ALA 226
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 108-185 7.49e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 58.97  E-value: 7.49e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315 108 ATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVTPSKMLIKNWLIQQ 185
Cdd:PRK07132   84 SSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKLLSK 161
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 52-170 9.48e-10

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 59.50  E-value: 9.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  52 MARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEA---DGhqikVDQIRELcsRLSAT--AQQSGRRVAII---Hhs 123
Cdd:PRK05563   58 FAKAVNCLNPPDGEPCNECEICKAITNGSLMDVIEIDAasnNG----VDEIRDI--RDKVKyaPSEAKYKVYIIdevH-- 129

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1709742315 124 erLNSASA-NALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK05563  130 --MLSTGAfNALLKTLEEPPAHVIFILATTEPHKIPATILSRCQRFDF 175
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 30-165 1.17e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 58.67  E-value: 1.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  30 KVPHAQLVGIDSAYGGELLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFYQIEAdGHQIKVDQIRELCSRLSAT 109
Cdd:PRK14961   36 RIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEIDA-ASRTKVEEMREILDNIYYS 114

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1709742315 110 AQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14961  115 PSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRC 170
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 23-165 1.43e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 58.97  E-value: 1.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  23 LTQlqtQKVPHAQL------VGIDSayggelLSVFMARAAMCSQPTPAGGCGFCKSCQLFDAGNHPDFyqIEADG-HQIK 95
Cdd:PRK14949   32 LTQ---QRLHHAYLftgtrgVGKTS------LARLFAKGLNCEQGVTATPCGVCSSCVEIAQGRFVDL--IEVDAaSRTK 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315  96 VDQIRELC-------SRlsataqqsGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK14949  101 VDDTRELLdnvqyrpSR--------GRfKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSRC 170
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 96-170 1.37e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 55.27  E-value: 1.37e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1709742315  96 VDQIRELCSRLSATAQQSGRRVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPF 170
Cdd:PRK14970   90 VDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDF 164
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
33-165 1.56e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.01  E-value: 1.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  33 HAQLVGIDSAYGGELLSVFMARAAMC-----SQPtpaggCGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELCSRlS 107
Cdd:PRK07003   39 HAYLFTGTRGVGKTTLSRIFAKALNCetgvtSQP-----CGVCRACREIDEGRFVDYVEMDAASNR-GVDEMAALLER-A 111

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1709742315 108 ATAQQSGR-RVAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK07003  112 VYAPVDARfKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRC 170
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
 53-167 4.53e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 54.14  E-value: 4.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  53 ARAAMCSQPTPAGG-----CGFCKSCQLFDAGNHPDFYQIEADGHQiKVDQIRELC--SRLSATaqqSGR-RVAIIHHSE 124
Cdd:PRK09111   67 ARALNYEGPDGDGGptidlCGVGEHCQAIMEGRHVDVLEMDAASHT-GVDDIREIIesVRYRPV---SARyKVYIIDEVH 142

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1709742315 125 RLNSASANALLKTLEEPgkdtllllhsdtPAR---LMA---------TISSRCQR 167
Cdd:PRK09111  143 MLSTAAFNALLKTLEEP------------PPHvkfIFAtteirkvpvTVLSRCQR 185
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 52-176 3.28e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 3.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  52 MARAAMCSQ---PTPaggCGFCKSCQ-LfdAGNHP---DFYQIEADGHQiKVDQIRELcsRLSAT-AQQSGR-RVAIIHH 122
Cdd:PRK07764   57 LARSLNCVEgptSTP---CGECDSCVaL--APGGPgslDVTEIDAASHG-GVDDAREL--RERAFfAPAESRyKIFIIDE 128

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709742315 123 SERLNSASANALLKTLEEPgkdtllllhsdtPARLM------------ATISSRCQRLPF--VTPSKM 176
Cdd:PRK07764  129 AHMVTPQGFNALLKIVEEP------------PEHLKfifattepdkviGTIRSRTHHYPFrlVPPEVM 184
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 62-165 3.53e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 45.24  E-value: 3.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  62 TPaggCGFCKSCQLFDAGNHPDFyqIEADG-HQIKVDQIRELC-------SRlsataqqsGR-RVAIIHHSERLNSASAN 132
Cdd:PRK07994   71 TP---CGECDNCREIEQGRFVDL--IEIDAaSRTKVEDTRELLdnvqyapAR--------GRfKVYLIDEVHMLSRHSFN 137

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1709742315 133 ALLKTLEEPGKDTLLLLHSDTPARLMATISSRC 165
Cdd:PRK07994  138 ALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC 170
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
81-187 4.58e-04

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 41.39  E-value: 4.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709742315  81 HPDFYQIEADGHQIKVDQIRELCSRLSATAqqsGRRVAIIHHSERLNSASAN--ALLKTLEEPGKDTLLLLHSDTP---A 155
Cdd:COG1466    32 DDGFNRTRLDGAETDWAELLDEAQTLSLFG---ERRLVIVRNAEFLKKPGEGleALEAYLANPPPDTVLVLTAGKLdkrK 108

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1709742315 156 RLMATISSRCQRLPFVTPSKMLIKNWLIQQCQ 187
Cdd:COG1466   109 KLFKALEKAGVVVECYPLKERELPAWIRQRLK 140
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
 117-164 3.13e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 38.09  E-value: 3.13e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1709742315 117 VAIIHHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSR 164
Cdd:PRK08485   57 KIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSR 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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