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Conserved domains on  [gi|1671187127|gb|TMG04999|]
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ABC transporter ATP-binding protein [Chloroflexi bacterium]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438927)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates; similar to Myxococcus xanthus O-antigen export system ATP-binding protein RfbB

CATH:  3.40.50.300
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 6-248 6.58e-119

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 345.53  E-value: 6.58e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFRVPLERTTSLKQLAARGfRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG1134     4 MIEVENVSKSYRLYHEPSRSLKELLLRR-RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTGLLSPFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQ 165
Cdd:COG1134    83 VEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 166 AHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAGAAVEYSRLNE 245
Cdd:COG1134   163 VDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAAYEALLA 242


                  ...
gi 1671187127 246 EHA 248
Cdd:COG1134   243 GRE 245
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 268-395 1.31e-19

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


:

Pssm-ID: 199902  Cd Length: 144  Bit Score: 84.72  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 268 RIVSVEMLDGNGQTTHAIQRGQSATIRLKIANPQR-EPVNAGVAIYRDDGLHCFGTNTVISHAAVPT-DAETVLLLDYQC 345
Cdd:cd10147    11 RITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDiEDPVVGFTIKDRDGQDVFGTNTLLLGGVLPSlKAGGEGEVEFTF 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 346 -MDLQHGTYWLTVGLFGGRLG-TVYEMLERLYSFHIGQSD--AYEGVVYMHHQW 395
Cdd:cd10147    91 pLPLNPGEYSLSVALADGDGHhEVLDWIDDALSFEVESSSksLFVGLVDLPHEW 144
 
Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 6-248 6.58e-119

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 345.53  E-value: 6.58e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFRVPLERTTSLKQLAARGfRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG1134     4 MIEVENVSKSYRLYHEPSRSLKELLLRR-RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTGLLSPFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQ 165
Cdd:COG1134    83 VEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 166 AHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAGAAVEYSRLNE 245
Cdd:COG1134   163 VDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAAYEALLA 242


                  ...
gi 1671187127 246 EHA 248
Cdd:COG1134   243 GRE 245
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 7-226 4.86e-101

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 299.06  E-value: 4.86e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPLERTTSLKQLAaRGFRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03220     1 IELENVSKSYPTYKGGSSSLKKLG-ILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGLLSPFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQA 166
Cdd:cd03220    80 TVRGRVSSLLGLGGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATAL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 167 HADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03220   160 EPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
4-226 3.06e-48

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 164.99  E-value: 3.06e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFRVPLERTTSLKQLAARGFRpagSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:PRK13546    2 NVSVNIKNVTKEYRIYRTNKERMKDALIPKHK---NKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVTGLLSpFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVA 163
Cdd:PRK13546   79 GKVDRNGEVS-VIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSIN 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 164 IQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13546  158 ITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGK 220
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 45-175 7.54e-27

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 104.65  E-value: 7.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI-------ELGV-----GFNAELTARENV 112
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDerkslrkEIGYvfqdpQLFPRLTVRENL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 113 FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNY----SSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGERpgtlSGGQRQRVAIARALLTKPKLLLLDE 147
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 44-232 5.68e-26

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 105.59  E-value: 5.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL--LSP----FIELGVGFnaeltarenVF---- 113
Cdd:TIGR04520  17 ALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLdtLDEenlwEIRKKVGM---------VFqnpd 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 --LSGAI-----------LGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVG 180
Cdd:TIGR04520  88 nqFVGATveddvafglenLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSML 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 181 DASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIqEFSDRVLILNHGR------PRGIYS 232
Cdd:TIGR04520 168 DPKGRKEVLETIRKLNKEeGITVISITHDMEEA-VLADRVIVMNKGKivaegtPREIFS 225
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
44-222 1.71e-22

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 93.84  E-value: 1.71e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSP-----FIELGVGFnaELTARENVFLSG-A 117
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVayvpqRSEVPDSL--PLTVRDLVAMGRwA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 118 ILGLSRSLVAE---RFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRR 194
Cdd:NF040873   85 RRGLWRRLTRDdraAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAE 164

                         170       180
                  ....*....|....*....|....*...
gi 1671187127 195 FKKEGRTIIFVSHDMGSIQEfSDRVLIL 222
Cdd:NF040873  165 EHARGATVVVVTHDLELVRR-ADPCVLL 191
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 268-395 1.31e-19

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


Pssm-ID: 199902  Cd Length: 144  Bit Score: 84.72  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 268 RIVSVEMLDGNGQTTHAIQRGQSATIRLKIANPQR-EPVNAGVAIYRDDGLHCFGTNTVISHAAVPT-DAETVLLLDYQC 345
Cdd:cd10147    11 RITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDiEDPVVGFTIKDRDGQDVFGTNTLLLGGVLPSlKAGGEGEVEFTF 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 346 -MDLQHGTYWLTVGLFGGRLG-TVYEMLERLYSFHIGQSD--AYEGVVYMHHQW 395
Cdd:cd10147    91 pLPLNPGEYSLSVALADGDGHhEVLDWIDDALSFEVESSSksLFVGLVDLPHEW 144
Wzt_C pfam14524
Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal ...
 268-391 1.75e-17

Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal structure of C-Wzt(O9a) reveals a beta sandwich with an immunoglobulin-like topology that contains the O-antigenic polysaccharide binding pocket. This domain is often associated with the ABC-transporter domain.


Pssm-ID: 464200  Cd Length: 141  Bit Score: 78.52  E-value: 1.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 268 RIVSVEMLDGNGQTTHAIQRGQSATIRLKIANPQR-EPVNAGVAIYRDDGLHCFGTNTVISHAAVP-TDAETVLLLDY-Q 344
Cdd:pfam14524   9 EIIDVELLDEDGKPTNTFESGEEVTLRIKVRFHEDvEDPIFGFTIKDRLGQEVFGTNTFLEGKSLGaLKAGEVVEVEFrF 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 345 CMDLQHGTYWLTVGLFG----GRLGTVYEMLERLYSFHIGQSDAYE--GVVYM 391
Cdd:pfam14524  89 KLNLQPGEYLLSVAIEDadgeQHEHVVYDWLDDALVFEVGVSSKNVfvGLVDL 141
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 54-222 9.98e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 59.69  E-value: 9.98e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   54 RGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllspfielgvgfnaeltarenvflsgailglsrsLVAERFDDI 133
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY------------------------------------IDGEDILEE 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  134 VRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ------EKCFDVFRRFKKEGRTIIFVSH 207
Cdd:smart00382  45 VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEalllllEELRLLLLLKSEKNLTVILTTN 124

                          170       180
                   ....*....|....*....|
gi 1671187127  208 DMGSIQE-----FSDRVLIL 222
Cdd:smart00382 125 DEKDLGPallrrRFDRRIVL 144
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
44-175 1.96e-10

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.83  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPfIELG-------VGF-------NAELTAR 109
Cdd:NF033858  281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFG--QP-VDAGdiatrrrVGYmsqafslYGELTVR 357

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIV-RFsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:NF033858  358 QNLELHARLFHLPAAEIAARVAEMLeRF-DLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
42-226 2.89e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 58.21  E-value: 2.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLlKIMAGIYRPTSGRV------------SVTGLLSPFIELGVGFNAELTAR 109
Cdd:NF000106   26 VKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRpwrf*twcanrrALRRTIG*HRPVR*GRRESFSGR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:NF000106  105 ENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVW 184

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:NF000106  185 DEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGR 221
GguA NF040905
sugar ABC transporter ATP-binding protein;
44-226 6.88e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 57.49  E-value: 6.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPT---SGRVSVTGLLSPF--I----ELGV-------GFNAELT 107
Cdd:NF040905   16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY-PHgsyEGEILFDGEVCRFkdIrdseALGIviihqelALIPYLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFL------SGAIlglSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGM--LVRLAFAVAiqAHADILLVDEVLAV 179
Cdd:NF040905   95 IAENIFLgnerakRGVI---DWNETNRRARELLAKVGLDESPDTLVTDIGVGKqqLVEIAKALS--KDVKLLILDEPTAA 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:NF040905  170 LNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGR 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
44-154 1.12e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.06  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLSPFIEL---GVGFN--AELTA 108
Cdd:NF033858   16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGgdmadarhrrAVCPRIAYmpqGLGKNlyPTLSV 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1671187127 109 RENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMD---QKLknySSGM 154
Cdd:NF033858   96 FENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADrpaGKL---SGGM 141
 
Name Accession Description Interval E-value
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 6-248 6.58e-119

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 345.53  E-value: 6.58e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFRVPLERTTSLKQLAARGfRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG1134     4 MIEVENVSKSYRLYHEPSRSLKELLLRR-RRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTGLLSPFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQ 165
Cdd:COG1134    83 VEVNGRVSALLELGAGFHPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 166 AHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAGAAVEYSRLNE 245
Cdd:COG1134   163 VDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAAYEALLA 242


                  ...
gi 1671187127 246 EHA 248
Cdd:COG1134   243 GRE 245
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 7-226 4.86e-101

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 299.06  E-value: 4.86e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPLERTTSLKQLAaRGFRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03220     1 IELENVSKSYPTYKGGSSSLKKLG-ILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGLLSPFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQA 166
Cdd:cd03220    80 TVRGRVSSLLGLGGGFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATAL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 167 HADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03220   160 EPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
7-226 3.82e-51

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 171.40  E-value: 3.82e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaargfrpagsrRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:COG1131     1 IEVRGLTKRYG-----------------------DKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEV 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGlLSPFIE-------LGV-----GFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGM 154
Cdd:COG1131    58 RVLG-EDVARDpaevrrrIGYvpqepALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGM 136

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 155 LVRLAFAVAIQAHADILLVDEVlAVG-DASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG1131   137 KQRLGLALALLHDPELLILDEP-TSGlDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGR 208
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
4-226 3.06e-48

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 164.99  E-value: 3.06e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFRVPLERTTSLKQLAARGFRpagSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:PRK13546    2 NVSVNIKNVTKEYRIYRTNKERMKDALIPKHK---NKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVTGLLSpFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVA 163
Cdd:PRK13546   79 GKVDRNGEVS-VIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSIN 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 164 IQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13546  158 ITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGK 220
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 7-245 4.71e-47

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 168.92  E-value: 4.71e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPLERTTSLKQLaargFRPAGSRRLE-ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:PRK13545    5 VKFEHVTKKYKMYNKPFDKLKDL----FFRSKDGEYHyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTGLLSpFIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQ 165
Cdd:PRK13545   81 VDIKGSAA-LIAISSGLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVH 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 166 AHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRgiyspagaavEYSRLNE 245
Cdd:PRK13545  160 INPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVK----------EYGDIKE 229
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 7-246 3.22e-46

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 158.87  E-value: 3.22e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrpaGSRRleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:COG4555     2 IEVENLSKKY---------------------GKVP--ALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSI 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL------LSPFIELGV-----GFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGML 155
Cdd:COG4555    59 LIDGEdvrkepREARRQIGVlpderGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMK 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 156 VRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAG 235
Cdd:COG4555   139 KKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDE 218

                         250
                  ....*....|.
gi 1671187127 236 AAVEYSRLNEE 246
Cdd:COG4555   219 LREEIGEENLE 229
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 7-226 1.56e-39

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 139.07  E-value: 1.56e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaargfrpagsrRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03230     1 IEVRNLSKRYG-----------------------KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEI 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGlLSPFIE-------LGV-----GFNAELTARENVflsgailglsrslvaerfddivrfselsdfmdqklkNYSSGM 154
Cdd:cd03230    58 KVLG-KDIKKEpeevkrrIGYlpeepSLYENLTVRENL------------------------------------KLSGGM 100

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 155 LVRLAFAVAIQAHADILLVDEVLaVG-DASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03230   101 KQRLALAQALLHDPELLILDEPT-SGlDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGR 172
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 42-226 6.79e-39

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 139.49  E-value: 6.79e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGlLSPF--IELGVG--------FnAEL 106
Cdd:cd03219    13 LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVlfdgeDITG-LPPHeiARLGIGrtfqiprlF-PEL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENV----------FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:cd03219    91 TVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEP 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 177 LA-VGDASfQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03219   171 AAgLNPEE-TEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGR 220
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 7-226 7.11e-39

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 139.39  E-value: 7.11e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVpLERTTSLKQlAARGFRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03267     1 IEVSNLSKSYRV-YSKEPGLIG-SLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGLLsPFIE-------LGVGFNA------ELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSG 153
Cdd:cd03267    79 RVAGLV-PWKRrkkflrrIGVVFGQktqlwwDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLG 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 154 MLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03267   158 QRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGR 231
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 43-226 3.89e-38

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 136.58  E-value: 3.89e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----LLSPFIELGV-----GFNAELTARENV 112
Cdd:cd03268    14 RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGksyqkNIEALRRIGAlieapGFYPNLTARENL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGAILGLSRSLVaERFDDIVrfsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVL----AVGDASFQEkc 188
Cdd:cd03268    94 RLLARLLGIRKKRI-DEVLDVV---GLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTngldPDGIKELRE-- 167

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1671187127 189 fdVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03268   168 --LILSLRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 43-233 8.24e-38

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 135.96  E-value: 8.24e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL--LSPFIE----LGVGF-----NAELTAREN 111
Cdd:cd03265    14 EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHdvVREPREvrrrIGIVFqdlsvDDELTGWEN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDV 191
Cdd:cd03265    94 LYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEY 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 192 FRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSP 233
Cdd:cd03265   174 IEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTP 216
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 44-226 1.05e-36

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 132.98  E-value: 1.05e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL---SPFIELG--VGF---NAE-----LTARE 110
Cdd:cd03225    16 ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDltkLSLKELRrkVGLvfqNPDdqffgPTVEE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFD 190
Cdd:cd03225    96 EVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLE 175

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 191 VFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03225   176 LLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-226 1.08e-36

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 134.06  E-value: 1.08e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   1 MQTDVAISIEHLTkvfrvplerttslkqlAARGFRPAgsrrleaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYR 80
Cdd:COG1121     1 MMMMPAIELENLT----------------VSYGGRPV-------LEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLP 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  81 PTSGRVSVTGLLSPFIELGVG-------FNAE--LTAREnVFLSGAI--LGLSRSLVA---ERFDDIVRFSELSDFMDQK 146
Cdd:COG1121    58 PTSGTVRLFGKPPRRARRRIGyvpqraeVDWDfpITVRD-VVLMGRYgrRGLFRRPSRadrEAVDEALERVGLEDLADRP 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 147 LKNYSSGMLVRLAFAVAIQAHADILLVDEVLAvG-DASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:COG1121   137 IGELSGGQQQRVLLARALAQDPDLLLLDEPFA-GvDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRG 215


                  .
gi 1671187127 226 R 226
Cdd:COG1121   216 L 216
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 7-234 2.30e-36

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 132.24  E-value: 2.30e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrpaGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03263     1 LQIRNLTKTY---------------------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTA 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTG------LLSPFIELGV--GFNA---ELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGML 155
Cdd:cd03263    60 YINGysirtdRKAARQSLGYcpQFDAlfdELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMK 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 156 VRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPA 234
Cdd:cd03263   140 RKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK-GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQ 217
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 43-225 3.25e-36

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 131.50  E-value: 3.25e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGVGF---------NAELTARENVF 113
Cdd:cd03235    13 PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYvpqrrsidrDFPISVRDVVL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 L-----SGAILGLSRSlVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:cd03235    93 MglyghKGLFRRLSKA-DKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDI 171

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 189 FDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:cd03235   172 YELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 7-227 2.57e-35

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 129.51  E-value: 2.57e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03293     1 LEVRNVSKTY-------------------GGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEV 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTG--LLSPFIELGVGFNAE-----LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLA 159
Cdd:cd03293    62 LVDGepVTGPGPDRGYVFQQDallpwLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVA 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 160 FAVAIQAHADILLVDEVLAVGDA----SFQEkcfDVFRRFKKEGRTIIFVSHDmgsIQE---FSDRVLILNhGRP 227
Cdd:cd03293   142 LARALAVDPDVLLLDEPFSALDAltreQLQE---ELLDIWRETGKTVLLVTHD---IDEavfLADRVVVLS-ARP 209
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 43-226 3.68e-35

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 129.37  E-value: 3.68e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL---SPFIELG--VGF---NAEL-----TAR 109
Cdd:COG1122    15 PALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDitkKNLRELRrkVGLvfqNPDDqlfapTVE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:COG1122    95 EDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELL 174

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG1122   175 ELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGR 211
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 42-226 5.21e-35

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 129.77  E-value: 5.21e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGlLSPF--IELGVG--------FnAEL 106
Cdd:COG0411    17 LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRIlfdgrDITG-LPPHriARLGIArtfqnprlF-PEL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENV----------FLSGAILGLSRSL-----VAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADIL 171
Cdd:COG0411    95 TVLENVlvaaharlgrGLLAALLRLPRARreereARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLL 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 172 LVDEVLA-VGDASFQEkCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG0411   175 LLDEPAAgLNPEETEE-LAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGR 230
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 7-226 1.11e-34

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 127.61  E-value: 1.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03255     1 IELKNLSKTY-------------------GGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEV 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL---------LSPFIELGVGF-----N--AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNY 150
Cdd:cd03255    62 RVDGTdisklsekeLAAFRRRHIGFvfqsfNllPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSEL 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 151 SSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMgSIQEFSDRVLILNHGR 226
Cdd:cd03255   142 SGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDP-ELAEYADRIIELRDGK 217
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 2-227 3.09e-34

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 127.90  E-value: 3.09e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   2 QTDVAISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRP 81
Cdd:COG1116     3 AAAPALELRGVSKRF-------------------PTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKP 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  82 TSGRVSVTG--LLSPFIELGVGFNAE-----LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGM 154
Cdd:COG1116    64 TSGEVLVDGkpVTGPGPDRGVVFQEPallpwLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGM 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 155 LVRLAFAVAIQAHADILLVDEVLAVGDA----SFQEkcfDVFRRFKKEGRTIIFVSHDmgsIQE---FSDRVLILnHGRP 227
Cdd:COG1116   144 RQRVAIARALANDPEVLLMDEPFGALDAltreRLQD---ELLRLWQETGKTVLFVTHD---VDEavfLADRVVVL-SARP 216
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 6-226 3.45e-34

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 129.44  E-value: 3.45e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFRVPlERTTSLKQLAARGFRPagSRRL-EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSG 84
Cdd:COG4586     1 IIEVENLSKTYRVY-EKEPGLKGALKGLFRR--EYREvEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  85 RVSVTGlLSPF---IEL----GVGF------NAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYS 151
Cdd:COG4586    78 EVRVLG-YVPFkrrKEFarriGVVFgqrsqlWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLS 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 152 SGMLVRLAFAVAIQAHADILLVDE------VLAvgdasfQEKcfdvFRRF-----KKEGRTIIFVSHDMGSIQEFSDRVL 220
Cdd:COG4586   157 LGQRMRCELAAALLHRPKILFLDEptigldVVS------KEA----IREFlkeynRERGTTILLTSHDMDDIEALCDRVI 226


                  ....*.
gi 1671187127 221 ILNHGR 226
Cdd:COG4586   227 VIDHGR 232
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 44-226 3.58e-33

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 121.58  E-value: 3.58e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLlspfielgvgfnaeltarenvflsgailGLSR 123
Cdd:cd00267    14 ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGK----------------------------DIAK 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 124 SLVAERFDDIVRFSELSdfmdqklknysSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTII 203
Cdd:cd00267    66 LPLEELRRRIGYVPQLS-----------GGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRTVI 134

                         170       180
                  ....*....|....*....|...
gi 1671187127 204 FVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd00267   135 IVTHDPELAELAADRVIVLKDGK 157
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 7-226 7.46e-33

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 122.86  E-value: 7.46e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPlerttslkqlaargfrpagSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03266     2 ITADALTKRFRDV-------------------KKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFA 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL---LSPF---IELGVGFNAE-----LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGML 155
Cdd:cd03266    63 TVDGFdvvKEPAearRRLGFVSDSTglydrLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMR 142

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 156 VRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03266   143 QKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGR 213
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4-226 3.88e-32

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 121.30  E-value: 3.88e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFRVplerttslkqlaargfrpaGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:COG1136     2 SPLLELRNLTKSYGT-------------------GEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTS 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVTGllspfIELG--------------VGF-----N--AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDF 142
Cdd:COG1136    63 GEVLIDG-----QDISslserelarlrrrhIGFvfqffNllPELTALENVALPLLLAGVSRKERRERARELLERVGLGDR 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 143 MDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE------------VLavgdasfqekcfDVFRRFKKE-GRTIIFVSHDM 209
Cdd:COG1136   138 LDHRPSQLSGGQQQRVAIARALVNRPKLILADEptgnldsktgeeVL------------ELLRELNRElGTTIVMVTHDP 205

                         250
                  ....*....|....*..
gi 1671187127 210 gSIQEFSDRVLILNHGR 226
Cdd:COG1136   206 -ELAARADRVIRLRDGR 221
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 38-208 2.04e-31

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 118.74  E-value: 2.04e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG------LLSPFIELGV-----GFNAEL 106
Cdd:COG4133    13 GERLL--FSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGepirdaREDYRRRLAYlghadGLKPEL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVFLSGAILGLSRSlvAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQE 186
Cdd:COG4133    91 TVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVA 168

                         170       180
                  ....*....|....*....|..
gi 1671187127 187 KCFDVFRRFKKEGRTIIFVSHD 208
Cdd:COG4133   169 LLAELIAAHLARGGAVLLTTHQ 190
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 40-226 2.58e-31

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 118.54  E-value: 2.58e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  40 RRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-LLSPFIELGVGFNAE-------LTAREN 111
Cdd:cd03269    11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGkPLDIAARNRIGYLPEerglypkMKVIDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDV 191
Cdd:cd03269    91 LVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDV 170

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1671187127 192 FRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03269   171 IRELARAGKTVILSTHQMELVEELCDRVLLLNKGR 205
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 7-226 5.16e-31

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 118.45  E-value: 5.16e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03258     2 IELKNVSKVF-------------------GDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSV 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTG----LLSPF------IELGV---GFN--AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYS 151
Cdd:cd03258    63 LVDGtdltLLSGKelrkarRRIGMifqHFNllSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLS 142

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1671187127 152 SGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03258   143 GGQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGE 218
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 6-228 1.09e-30

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 119.06  E-value: 1.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFrvplerttslkqlaargfrpaGSRRleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG4152     1 MLELKGLTKRF---------------------GDKT--AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGE 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTG-LLSPFIELGVGFNAE-------LTAREN-VFLsGAILGLSRSLVAERFDD-IVRFsELSDFMDQKLKNYSSGML 155
Cdd:COG4152    58 VLWDGePLDPEDRRRIGYLPEerglypkMKVGEQlVYL-ARLKGLSKAEAKRRADEwLERL-GLGDRANKKVEELSKGNQ 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 156 VRLAFAVAIQAHADILLVDE-----------VLAvgdasfqekcfDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNH 224
Cdd:COG4152   136 QKVQLIAALLHDPELLILDEpfsgldpvnveLLK-----------DVIRELAAKGTTVIFSSHQMELVEELCDRIVIINK 204


                  ....
gi 1671187127 225 GRPR 228
Cdd:COG4152   205 GRKV 208
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 37-226 8.93e-30

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 114.84  E-value: 8.93e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  37 AGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVS-----VTGlLSPF--IELGVGFNAE---- 105
Cdd:cd03224     8 AGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRfdgrdITG-LPPHerARAGIGYVPEgrri 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 ---LTARENVFLsgAILGLSRSLVAERFDDIV-RFSELSDFMDQKLKNYSSG---MlvrLAFAVAIQAHADILLVDEVLA 178
Cdd:cd03224    87 fpeLTVEENLLL--GAYARRRAKRKARLERVYeLFPRLKERRKQLAGTLSGGeqqM---LAIARALMSRPKLLLLDEPSE 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1671187127 179 vGDA-SFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03224   162 -GLApKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGR 209
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 43-226 3.27e-29

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 111.37  E-value: 3.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPF--IELGVGFnaeltarenVF-LS 115
Cdd:cd03216    14 KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGkevsFASPRdaRRAGIAM---------VYqLS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAIlglsRSLVAerfddIVRfselsdfmdqklknyssgmlvrlafavAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF 195
Cdd:cd03216    85 VGE----RQMVE-----IAR---------------------------ALARNARLLILDEPTAALTPAEVERLFKVIRRL 128

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 196 KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03216   129 RAQGVAVIFISHRLDEVFEIADRVTVLRDGR 159
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 6-226 4.27e-29

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 113.74  E-value: 4.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFRvplerttslkqlaargfrpAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG1124     1 MLEVRNLSVSYG-------------------QGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGE 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VSVTGLLSPFIELGVG--------------FNAELTARENVFLSGAILGLSRslVAERFDDIVRFSEL-SDFMDQKLKNY 150
Cdd:COG1124    62 VTFDGRPVTRRRRKAFrrrvqmvfqdpyasLHPRHTVDRILAEPLRIHGLPD--REERIAELLEQVGLpPSFLDRYPHQL 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 151 SSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG1124   140 SGGQRQRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREErGLTYLFVSHDLAVVAHLCDRVAVMQNGR 216
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 44-226 5.98e-29

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 112.23  E-value: 5.98e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVS-----VTGLlsPFIELGVGFNAE-------LTAREN 111
Cdd:cd03259    15 ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILidgrdVTGV--PPERRNIGMVFQdyalfphLTVAEN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDV 191
Cdd:cd03259    93 IAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREE 172

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 192 FRR-FKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03259   173 LKElQRELGITTIYVTHDQEEALALADRIAVMNEGR 208
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 2-226 1.25e-28

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 117.31  E-value: 1.25e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   2 QTDVAISIEHLTKVFRVPlerttslkqlaargfrpaGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRP 81
Cdd:COG1123   256 AAEPLLEVRNLSKRYPVR------------------GKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRP 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  82 TSGRVSVTGL-LSPFIELG-------VG---------FNAELTARENVFLSGAILG-LSRSLVAERFDDIVRFSELS-DF 142
Cdd:COG1123   318 TSGSILFDGKdLTKLSRRSlrelrrrVQmvfqdpyssLNPRMTVGDIIAEPLRLHGlLSRAERRERVAELLERVGLPpDL 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 143 MDQklknY----SSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSD 217
Cdd:COG1123   398 ADR----YphelSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYIAD 473


                  ....*....
gi 1671187127 218 RVLILNHGR 226
Cdd:COG1123   474 RVAVMYDGR 482
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 44-231 4.41e-28

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 110.40  E-value: 4.41e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGLLSPFIELGVGFNA-----ELTARENVF 113
Cdd:cd03300    15 ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEIlldgkDITNLPPHKRPVNTVFQNyalfpHLTVFENIA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 LSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFR 193
Cdd:cd03300    95 FGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELK 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 194 RFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIY 231
Cdd:cd03300   175 RLQKElGITFVFVTHDQEEALTMSDRIAVMNKGKiqqigtPEEIY 219
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
43-226 6.28e-28

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 109.76  E-value: 6.28e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLS----PFI--ELGVGFN-----AELT 107
Cdd:COG2884    16 EALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGqdlsRLKrreiPYLrrRIGVVFQdfrllPDRT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:COG2884    96 VYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPETSWE 175

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 188 CFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG2884   176 IMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGR 214
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 45-226 2.01e-27

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 108.58  E-value: 2.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPfIELGVGFNAE-------LTARENVF 113
Cdd:cd03299    15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGkditNLPP-EKRDISYVPQnyalfphMTVYKNIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 LSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFR 193
Cdd:cd03299    94 YGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELK 173

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1671187127 194 RFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03299   174 KIRKEfGVTVLHVTHDFEEAWALADKVAIMLNGK 207
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 7-226 2.22e-27

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 108.36  E-value: 2.22e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVplerttslkqlaargfrpaGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03257     2 LEVKNLSVSFPT-------------------GGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSI 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTG----LLSPFIELGVG-------------FNAELTARENvfLSGAILGLSRSLVAERFDDI-----VRFSELSDFMD 144
Cdd:cd03257    63 IFDGkdllKLSRRLRKIRRkeiqmvfqdpmssLNPRMTIGEQ--IAEPLRIHGKLSKKEARKEAvllllVGVGLPEEVLN 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 145 QKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILN 223
Cdd:cd03257   141 RYPHELSGGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMY 220


                  ...
gi 1671187127 224 HGR 226
Cdd:cd03257   221 AGK 223
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 45-175 7.54e-27

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 104.65  E-value: 7.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI-------ELGV-----GFNAELTARENV 112
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDerkslrkEIGYvfqdpQLFPRLTVRENL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 113 FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNY----SSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGERpgtlSGGQRQRVAIARALLTKPKLLLLDE 147
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 43-226 1.98e-26

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 104.44  E-value: 1.98e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPfielgvgfnAELtARENVFLSGAI 118
Cdd:cd03214    13 TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKdlasLSP---------KEL-ARKIAYVPQAL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 119 --LGLSrSLvAERfddivRFSELSDFMDQKlknyssgmlVRLAFAVAIQahADILLVDEVLAVGDASFQEKCFDVFRRFK 196
Cdd:cd03214    83 elLGLA-HL-ADR-----PFNELSGGERQR---------VLLARALAQE--PPILLLDEPTSHLDIAHQIELLELLRRLA 144

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 197 KE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03214   145 RErGKTVVMVLHDLNLAARYADRVILLKDGR 175
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
44-222 2.52e-26

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 110.11  E-value: 2.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPF--IELGVG-----FN--AELTARE 110
Cdd:COG1129    19 ALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGepvrFRSPRdaQAAGIAiihqeLNlvPNLSVAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLSGAILG---LSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGM--LVrlAFAVAIQAHADILLVDE---VLAVGDA 182
Cdd:COG1129    99 NIFLGREPRRgglIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQqqLV--EIARALSRDARVLILDEptaSLTEREV 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1671187127 183 sfqEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLIL 222
Cdd:COG1129   177 ---ERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVL 213
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 44-226 5.53e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 109.35  E-value: 5.53e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPF--IELGVG--------FNAeLTAR 109
Cdd:COG3845    20 ANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGkpvrIRSPRdaIALGIGmvhqhfmlVPN-LTVA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLS---GAILGLSRSLVAERfddIVRFSELSDF---MDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE---VLAVG 180
Cdd:COG3845    99 ENIVLGlepTKGGRLDRKAARAR---IRELSERYGLdvdPDAKVEDLSVGEQQRVEILKALYRGARILILDEptaVLTPQ 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 181 DAsfqEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG3845   176 EA---DELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGK 218
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 44-232 5.68e-26

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 105.59  E-value: 5.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL--LSP----FIELGVGFnaeltarenVF---- 113
Cdd:TIGR04520  17 ALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLdtLDEenlwEIRKKVGM---------VFqnpd 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 --LSGAI-----------LGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVG 180
Cdd:TIGR04520  88 nqFVGATveddvafglenLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSML 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 181 DASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIqEFSDRVLILNHGR------PRGIYS 232
Cdd:TIGR04520 168 DPKGRKEVLETIRKLNKEeGITVISITHDMEEA-VLADRVIVMNKGKivaegtPREIFS 225
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 41-226 1.88e-25

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 103.14  E-value: 1.88e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGlLSPF--IELGVG--------FnAE 105
Cdd:COG0410    15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIrfdgeDITG-LPPHriARLGIGyvpegrriF-PS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVFLsGAILGLSRSLVAERFDDIV-RFSELSDFMDQK---LknysSG----MlvrLAFAVAIQAHADILLVDEV- 176
Cdd:COG0410    93 LTVEENLLL-GAYARRDRAEVRADLERVYeLFPRLKERRRQRagtL----SGgeqqM---LAIGRALMSRPKLLLLDEPs 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 177 --LAvgdASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG0410   165 lgLA---PLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGR 213
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 38-273 6.24e-25

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 106.53  E-value: 6.24e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPT---SGRVSVTGL----LSPFI---ELGVGF-NAE- 105
Cdd:COG1123    15 PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRdlleLSEALrgrRIGMVFqDPMt 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 ----LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:COG1123    95 qlnpVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 182 ASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAGAAVEYSRLNEehANRLLSDSKAAPT 260
Cdd:COG1123   175 VTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQALAA--VPRLGAARGRAAP 252

                         250
                  ....*....|...
gi 1671187127 261 SATSSRPrIVSVE 273
Cdd:COG1123   253 AAAAAEP-LLEVR 264
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-234 6.87e-25

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 104.41  E-value: 6.87e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   1 MQTdVAISIEHLTKVFrvplerttslkqlaargfrpaGSRRleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYR 80
Cdd:COG3842     1 MAM-PALELENVSKRY---------------------GDVT--ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFET 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  81 PTSGRV-----SVTGL---------------LSPFielgvgfnaeLTARENV--FLSgaILGLSRSLVAERFDDIVRFSE 138
Cdd:COG3842    57 PDSGRIlldgrDVTGLppekrnvgmvfqdyaLFPH----------LTVAENVafGLR--MRGVPKAEIRARVAELLELVG 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 139 LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK-CFDVFRRFKKEGRTIIFVSHDmgsiQE--- 214
Cdd:COG3842   125 LEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEmREELRRLQRELGITFIYVTHD----QEeal 200

                         250       260
                  ....*....|....*....|....*...
gi 1671187127 215 -FSDRVLILNHGR------PRGIYS-PA 234
Cdd:COG3842   201 aLADRIAVMNDGRieqvgtPEEIYErPA 228
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 44-226 6.94e-25

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 99.95  E-value: 6.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfielgvgfnaeltarENVFLSGAILGLSR 123
Cdd:cd03229    15 VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDG-------------------EDLTDLEDELPPLR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 124 SLVAERFDDIVRFSELSdfmdqKLKN----YSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE- 198
Cdd:cd03229    76 RRIGMVFQDFALFPHLT-----VLENialgLSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQl 150

                         170       180
                  ....*....|....*....|....*...
gi 1671187127 199 GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03229   151 GITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 45-226 6.98e-25

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 101.81  E-value: 6.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLSPFIELGVGF--NA---ELTAR 109
Cdd:cd03261    16 LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGedisglseaeLYRLRRRMGMLFqsGAlfdSLTVF 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENV-FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA----VGDASF 184
Cdd:cd03261    96 ENVaFPLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAgldpIASGVI 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 185 QekcfDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03261   176 D----DLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGK 214
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
44-226 8.99e-25

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 102.40  E-value: 8.99e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPF----IELGVGF---NAE-----LTARE 110
Cdd:PRK13635   22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMvLSEEtvwdVRRQVGMvfqNPDnqfvgATVQD 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFD 190
Cdd:PRK13635  102 DVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLE 181

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 191 VFRRFKKEGR-TIIFVSHDmgsIQE--FSDRVLILNHGR 226
Cdd:PRK13635  182 TVRQLKEQKGiTVLSITHD---LDEaaQADRVIVMNKGE 217
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 44-226 1.85e-24

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 100.17  E-value: 1.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LS-------PFI--ELGVGFN-----AELTA 108
Cdd:cd03292    16 ALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQdVSdlrgraiPYLrrKIGVVFQdfrllPDRNV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 109 RENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:cd03292    96 YENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEI 175

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1671187127 189 FDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03292   176 MNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGK 213
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
7-226 1.92e-24

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 102.85  E-value: 1.92e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:COG1135     2 IELENLSKTF-------------------PTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSV 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL----LSPfIEL-----GVG-----FN--AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNY 150
Cdd:COG1135    63 LVDGVdltaLSE-RELraarrKIGmifqhFNllSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQL 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 151 SSGMLVRLAFAVAIQAHADILLVDE------------VLavgdasfqekcfDVFRRFKKE-GRTIIFVSHDMGSIQEFSD 217
Cdd:COG1135   142 SGGQKQRVGIARALANNPKVLLCDEatsaldpettrsIL------------DLLKDINRElGLTIVLITHEMDVVRRICD 209


                  ....*....
gi 1671187127 218 RVLILNHGR 226
Cdd:COG1135   210 RVAVLENGR 218
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 7-226 2.04e-24

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 99.96  E-value: 2.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaargfrpagsrRLEALQDVSIEITRGeFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03264     1 LQLENLTKRYG-----------------------KKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGLLSP-----------FIELGVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGML 155
Cdd:cd03264    57 RIDGQDVLkqpqklrrrigYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMR 136

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 156 VRLAFAVAIQAHADILLVDEVLAVGDASFQEKcfdvFRRFKKE---GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03264   137 RRVGIAQALVGDPSILIVDEPTAGLDPEERIR----FRNLLSElgeDRIVILSTHIVEDVESLCNQVAVLNKGK 206
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 2-226 2.19e-24

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 100.44  E-value: 2.19e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   2 QTDVAISIEHLTKVFrvplerttslkqlaargfrpaGSRrlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRP 81
Cdd:COG1127     1 MSEPMIEVRNLTKSF---------------------GDR--VVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRP 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  82 TSGRVSVTG----------LLSPFIELGVGF--NA---ELTARENVflsgAI-----LGLSRSLVAERFDDIVRFSELSD 141
Cdd:COG1127    58 DSGEILVDGqditglsekeLYELRRRIGMLFqgGAlfdSLTVFENV----AFplrehTDLSEAEIRELVLEKLELVGLPG 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 142 FMDQK---LknySSGMLVRLAFAVAIQAHADILLVDEVLA----VGDASFQEkcfdVFRRFKKE-GRTIIFVSHDMGSIQ 213
Cdd:COG1127   134 AADKMpseL---SGGMRKRVALARALALDPEILLYDEPTAgldpITSAVIDE----LIRELRDElGLTSVVVTHDLDSAF 206

                         250
                  ....*....|...
gi 1671187127 214 EFSDRVLILNHGR 226
Cdd:COG1127   207 AIADRVAVLADGK 219
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 41-234 2.72e-24

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 100.11  E-value: 2.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS---PFIELGVGFNAE-------LTARE 110
Cdd:cd03296    14 DFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDAtdvPVQERNVGFVFQhyalfrhMTVFD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVflsgaILGL---------SRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:cd03296    94 NV-----AFGLrvkprserpPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALD 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 182 ASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPA 234
Cdd:cd03296   169 AKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPD 222
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 42-226 6.78e-24

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 98.37  E-value: 6.78e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--LLSPFIEL-----GVG-----FN--AELT 107
Cdd:cd03262    13 FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGlkLTDDKKNInelrqKVGmvfqqFNlfPHLT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLsGAI--LGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ 185
Cdd:cd03262    93 VLENITL-APIkvKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELV 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1671187127 186 EKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03262   172 GEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 7-226 9.25e-24

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 98.91  E-value: 9.25e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaarGFRPAgsrrleaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:cd03295     1 IEFENVTKRYG---------------GGKKA-------VNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEI 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL----LSPfIEL---------GVGFNAELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSD--FMDQKLKNYS 151
Cdd:cd03295    59 FIDGEdireQDP-VELrrkigyviqQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPaeFADRYPHELS 137

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1671187127 152 SGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03295   138 GGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGE 213
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
29-226 1.66e-23

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 97.19  E-value: 1.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFR-PAGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-LLSPfielgvgFNAEl 106
Cdd:COG4619     1 LELEGLSfRVGGKPI--LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGkPLSA-------MPPP- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVFLSGAILGLSRSLVAERFDDIVRFSELS-----------------DFMDQKLKNYSSGMLVRLAFAVAIQAHAD 169
Cdd:COG4619    71 EWRRQVAYVPQEPALWGGTVRDNLPFPFQLRERKfdreralellerlglppDILDKPVERLSGGERQRLALIRALLLQPD 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 170 ILLVDEVLAVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4619   151 VLLLDEPTSALDPENTRRVEELLREYlAEEGRAVLWVSHDPEQIERVADRVLTLEAGR 208
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 38-226 2.08e-23

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 98.19  E-value: 2.08e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------------LLSPFIELGVG 101
Cdd:COG1120    12 GGRPV--LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGrdlaslsrrelarriaYVPQEPPAPFG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 102 FnaelTARENVFL-----SGAILGLS---RSLVA---ERFDdivrfseLSDFMDQKLKNYSSGMLVRLAFAVAIQAHADI 170
Cdd:COG1120    90 L----TVRELVALgryphLGLFGRPSaedREAVEealERTG-------LEHLADRPVDELSGGERQRVLIARALAQEPPL 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 171 LLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG1120   159 LLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGR 215
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 43-226 2.39e-23

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 97.64  E-value: 2.39e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPFIELGV---------GFN--AELT 107
Cdd:cd03256    15 KALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTdinkLKGKALRQLrrqigmifqQFNliERLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVfLSGAI--LGLSRSLvAERFD--DIVRFSE------LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVL 177
Cdd:cd03256    95 VLENV-LSGRLgrRSTWRSL-FGLFPkeEKQRALAalervgLLDKAYQRADQLSGGQQQRVAIARALMQQPKLILADEPV 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1671187127 178 AVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03256   173 ASLDPASSRQVMDLLKRInREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 7-238 2.56e-23

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 99.84  E-value: 2.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaarGFRpagsrrleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:COG1118     3 IEVRNISKRFG---------------SFT--------LLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRI 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL-----LSPFiELGVGF---NAEL----TARENV--FLSgaILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSS 152
Cdd:COG1118    60 VLNGRdlftnLPPR-ERRVGFvfqHYALfphmTVAENIafGLR--VRPPSKAEIRARVEELLELVQLEGLADRYPSQLSG 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 153 GMLVRLAFAVAIQAHADILLVDEVLAVGDASfqekcfdV--------FRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNH 224
Cdd:COG1118   137 GQRQRVALARALAVEPEVLLLDEPFGALDAK-------VrkelrrwlRRLHDELGGTTVFVTHDQEEALELADRVVVMNQ 209

                         250       260
                  ....*....|....*....|.
gi 1671187127 225 GR------PRGIY-SPAGAAV 238
Cdd:COG1118   210 GRieqvgtPDEVYdRPATPFV 230
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 44-226 4.03e-23

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 96.17  E-value: 4.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPFiELGVGF---NAEL----TARENV 112
Cdd:cd03301    15 ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRdvtdLPPK-DRDIAMvfqNYALyphmTVYDNI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVF 192
Cdd:cd03301    94 AFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAEL 173

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1671187127 193 RRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03301   174 KRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQ 208
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 7-239 8.27e-23

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 96.94  E-value: 8.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvpLERTTSLKQLAARGFRPAGSRR----LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPT 82
Cdd:cd03294     1 IKIKGLYKIF---GKNPQKAFKLLAKGKSKEEILKktgqTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPT 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  83 SGRVSVTGL------LSPFIEL-----GVGFNA-----ELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQK 146
Cdd:cd03294    78 SGKVLIDGQdiaamsRKELRELrrkkiSMVFQSfallpHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKY 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 147 LKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:cd03294   158 PDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAElQKTIVFITHDLDEALRLGDRIAIMKDG 237

                         250       260
                  ....*....|....*....|.
gi 1671187127 226 R------PRGIY-SPAGAAVE 239
Cdd:cd03294   238 RlvqvgtPEEILtNPANDYVR 258
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-226 1.29e-22

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 100.29  E-value: 1.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFRVPLERTTSLKQLAARGFRPA----------GSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLK 73
Cdd:COG2274   440 DAKIALERLDDILDLPPEREEGRSKLSLPRLKGDielenvsfryPGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLK 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  74 IMAGIYRPTSGRVSVTGL----LSPfIEL----G-VGFNAEL---TARENVFLSGAILGLsrslvaERFDDIVRFSELSD 141
Cdd:COG2274   520 LLLGLYEPTSGRILIDGIdlrqIDP-ASLrrqiGvVLQDVFLfsgTIRENITLGDPDATD------EEIIEAARLAGLHD 592

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 142 F-------MDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMG 210
Cdd:COG2274   593 FiealpmgYDTVVgeggSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK-GRTVIIIAHRLS 671

                         250
                  ....*....|....*.
gi 1671187127 211 SIQEfSDRVLILNHGR 226
Cdd:COG2274   672 TIRL-ADRIIVLDKGR 686
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
44-222 1.71e-22

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 93.84  E-value: 1.71e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSP-----FIELGVGFnaELTARENVFLSG-A 117
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVayvpqRSEVPDSL--PLTVRDLVAMGRwA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 118 ILGLSRSLVAE---RFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRR 194
Cdd:NF040873   85 RRGLWRRLTRDdraAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAE 164

                         170       180
                  ....*....|....*....|....*...
gi 1671187127 195 FKKEGRTIIFVSHDMGSIQEfSDRVLIL 222
Cdd:NF040873  165 EHARGATVVVVTHDLELVRR-ADPCVLL 191
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 43-226 2.54e-22

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 94.55  E-value: 2.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIY-----RPTSGRVS-----VTGLLSPFIEL--GVG--------F 102
Cdd:cd03260    14 HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLldgkdIYDLDVDVLELrrRVGmvfqkpnpF 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 NAelTARENVFLSGAILGLSRslvAERFDDIVRFS----ELSDFMDQKLKNY--SSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:cd03260    94 PG--SIYDNVAYGLRLHGIKL---KEELDERVEEAlrkaALWDEVKDRLHALglSGGQQQRLCLARALANEPEVLLLDEP 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1671187127 177 LAVGDASFQEKCFDVFRRFKKEgRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03260   169 TSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGR 217
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 43-226 3.69e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 95.19  E-value: 3.69e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSP----FIELGVG----------FNAelT 107
Cdd:PRK13647   19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGReVNAenekWVRSKVGlvfqdpddqvFSS--T 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:PRK13647   97 VWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQET 176

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 188 CFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13647  177 LMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGR 215
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 6-238 4.67e-22

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 96.30  E-value: 4.67e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   6 AISIEHLTKVFrvplerttslkqlaargfrpaGSRrlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGR 85
Cdd:COG3839     3 SLELENVSKSY---------------------GGV--EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGE 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  86 VS-----VTGL---------------LSPFielgvgfnaeLTARENV-F-LSgaILGLSRSLVAERFDDIVRFSELSDFM 143
Cdd:COG3839    60 ILiggrdVTDLppkdrniamvfqsyaLYPH----------MTVYENIaFpLK--LRKVPKAEIDRRVREAAELLGLEDLL 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 144 DQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDmgsiQE----FSDR 218
Cdd:COG3839   128 DRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRlGTTTIYVTHD----QVeamtLADR 203

                         250       260
                  ....*....|....*....|....*..
gi 1671187127 219 VLILNHGR------PRGIY-SPAGAAV 238
Cdd:COG3839   204 IAVMNDGRiqqvgtPEELYdRPANLFV 230
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 38-226 3.46e-21

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 89.75  E-value: 3.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL------------------SPFIelg 99
Cdd:cd03228    11 PGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDlrdldleslrkniayvpqDPFL--- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 100 vgFNAelTARENVfLSGailGlsrslvaERfddivrfselsdfmdQklknyssgmlvRLAFAVAIQAHADILLVDEVLAV 179
Cdd:cd03228    88 --FSG--TIRENI-LSG---G-------QR---------------Q-----------RIAIARALLRDPPILILDEATSA 126

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:cd03228   127 LDPETEALILEALRALAK-GKTVIVIAHRLSTIRDA-DRIIVLDDGR 171
cbiO PRK13641
energy-coupling factor transporter ATPase;
34-232 4.44e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 92.20  E-value: 4.44e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----------LLSPFIELGVGF 102
Cdd:PRK13641   12 YSPGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGyhitpetgnknLKKLRKKVSLVF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 NA------ELTARENVFLSGAILGLSRSLVAERFDDIVRFSELS-DFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:PRK13641   92 QFpeaqlfENTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDE 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 176 VLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIYS 232
Cdd:PRK13641  172 PAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKlikhasPKEIFS 234
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
44-226 1.26e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 93.44  E-value: 1.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGVGFNA-------------ELTARE 110
Cdd:PRK11288   19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAgvaiiyqelhlvpEMTVAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLsGAI---LGL--SRSLVAERFDDIVRFSELSDfMDQKLKNYSSG--MLVRLAFAVAIQAHadILLVDEVLAVGDAS 183
Cdd:PRK11288   99 NLYL-GQLphkGGIvnRRLLNYEAREQLEHLGVDID-PDTPLKYLSIGqrQMVEIAKALARNAR--VIAFDEPTSSLSAR 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 184 FQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11288  175 EIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGR 217
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 43-225 1.31e-20

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 89.24  E-value: 1.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIEL--GVGF-----NAEL---TARENV 112
Cdd:cd03226    14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERrkSIGYvmqdvDYQLftdSVREEL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGAILGLSrslvAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVF 192
Cdd:cd03226    94 LLGLKELDAG----NEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELI 169

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1671187127 193 RRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:cd03226   170 RELAAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
42-225 2.43e-20

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 92.93  E-value: 2.43e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPFI--ELGVGF-------NAELTA 108
Cdd:PRK09700   18 VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNInynkLDHKLaaQLGIGIiyqelsvIDELTV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 109 RENVF----LSGAILGLS---RSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:PRK09700   98 LENLYigrhLTKKVCGVNiidWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLT 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1671187127 182 ASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK09700  178 NKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDG 221
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 45-225 3.96e-20

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 88.29  E-value: 3.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--LLSPFIELGVGF-NAEL----TARENVFLS-- 115
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGkqITEPGPDRMVVFqNYSLlpwlTVRENIALAvd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA----SFQEKCFDV 191
Cdd:TIGR01184  81 RVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAltrgNLQEELMQI 160

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1671187127 192 frrFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:TIGR01184 161 ---WEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
cbiO PRK13637
energy-coupling factor transporter ATPase;
43-226 4.34e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 89.72  E-value: 4.34e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL--------LSpFI--ELGVGFNA------EL 106
Cdd:PRK13637   21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVditdkkvkLS-DIrkKVGLVFQYpeyqlfEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVFLSGAILGLSRSLVAERFDDIVRFSELS--DFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASF 184
Cdd:PRK13637  100 TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKG 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 185 QEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13637  180 RDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGK 222
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 7-226 4.94e-20

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 88.13  E-value: 4.94e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrpaGSrrLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:COG1126     2 IEIENLHKSF---------------------GD--LEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTI 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTG--LLSPFIEL-----GVG-----FN--AELTARENVFLsgA---ILGLSRS---LVAERFDDIVRfseLSDFMDQK 146
Cdd:COG1126    59 TVDGedLTDSKKDInklrrKVGmvfqqFNlfPHLTVLENVTL--ApikVKKMSKAeaeERAMELLERVG---LADKADAY 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 147 LKNYSSGMLVRLAFAVAIQAHADILL------------VDEVLavgdasfqekcfDVFRRFKKEGRTIIFVSHDMGSIQE 214
Cdd:COG1126   134 PAQLSGGQQQRVAIARALAMEPKVMLfdeptsaldpelVGEVL------------DVMRDLAKEGMTMVVVTHEMGFARE 201

                         250
                  ....*....|..
gi 1671187127 215 FSDRVLILNHGR 226
Cdd:COG1126   202 VADRVVFMDGGR 213
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
47-226 6.90e-20

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 89.89  E-value: 6.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  47 DVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSP----FIELGVG-------FNAELTARENVFLS 115
Cdd:PRK13536   59 GLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPararLARARIGvvpqfdnLDLEFTVRENLLVF 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF 195
Cdd:PRK13536  139 GRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSL 218

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 196 KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13536  219 LARGKTILLTTHFMEEAERLCDRLCVLEAGR 249
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 45-226 8.88e-20

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 87.83  E-value: 8.88e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS-----------GRVSVT------GLLSPfiELGVGFNAELT 107
Cdd:COG1119    19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYgndvrlfgerrGGEDVWelrkriGLVSP--ALQLRFPRDET 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 AREnVFLSG--AILGLSRSLVAE---RFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:COG1119    97 VLD-VVLSGffDSIGLYREPTDEqreRARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDL 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 183 SFQEKCFDVFRRFKKEG-RTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG1119   176 GARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGR 220
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 7-226 9.00e-20

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 89.47  E-value: 9.00e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFrvplerttslkqlaargfrPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:PRK11153    2 IELKNISKVF-------------------PQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRV 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  87 SVTGL----LSPfIEL-----GVG-----FN--AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNY 150
Cdd:PRK11153   63 LVDGQdltaLSE-KELrkarrQIGmifqhFNllSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQL 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 151 SSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11153  142 SGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGR 218
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 43-226 1.20e-19

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 86.87  E-value: 1.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPF-IELGVGF---NAEL---TAREN 111
Cdd:cd03245    18 PALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTdirqLDPAdLRRNIGYvpqDVTLfygTLRDN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 vflsgaiLGLSRSLVA-ERFDDIVRFSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:cd03245    98 -------ITLGAPLADdERILRAAELAGVTDFVNKHPNGLdlqigergrglSGGQRQAVALARALLNDPPILLLDEPTSA 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFkKEGRTIIFVSHDMgSIQEFSDRVLILNHGR 226
Cdd:cd03245   171 MDMNSEERLKERLRQL-LGDKTLIIITHRP-SLLDLVDRIIVMDSGR 215
Wzt_C-like cd10147
C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; ...
 268-395 1.31e-19

C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; The Escherichia coli ABC protein Wzt consists of 2 domains, a conventional ABC domain that binds ATP and utilizes its energy to transport molecules across membranes, and a C terminal domain which is responsible for its target molecule specificity. Wzt is part of the ATP-binding-cassette (ABC) transporter complex, responsible for the transport of the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria. This CD includes Wzt proteins from two Escherichia coli serotypes O8 and O9a, WztO8 and WztO9a; these proteins are specific for their cognate polysaccharides (O8 or O9a O-PS).


Pssm-ID: 199902  Cd Length: 144  Bit Score: 84.72  E-value: 1.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 268 RIVSVEMLDGNGQTTHAIQRGQSATIRLKIANPQR-EPVNAGVAIYRDDGLHCFGTNTVISHAAVPT-DAETVLLLDYQC 345
Cdd:cd10147    11 RITDVELLDEDGEPVNTFRSGEPVTLRIEYEVNEDiEDPVVGFTIKDRDGQDVFGTNTLLLGGVLPSlKAGGEGEVEFTF 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 346 -MDLQHGTYWLTVGLFGGRLG-TVYEMLERLYSFHIGQSD--AYEGVVYMHHQW 395
Cdd:cd10147    91 pLPLNPGEYSLSVALADGDGHhEVLDWIDDALSFEVESSSksLFVGLVDLPHEW 144
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 44-226 1.62e-19

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 85.98  E-value: 1.62e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS-----PFIelgvgFNAelTARENvflsgaI 118
Cdd:cd03250    20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSIAyvsqePWI-----QNG--TIREN------I 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 119 LGLSRsLVAERFDDIVRFSELsdfmDQKLKNYSSGMLV---------------RLAFAVAIQAHADILLVDEVLAVGDAS 183
Cdd:cd03250    87 LFGKP-FDEERYEKVIKACAL----EPDLEILPDGDLTeigekginlsggqkqRISLARAVYSDADIYLLDDPLSAVDAH 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1671187127 184 FQEKCFD-VFRRFKKEGRTIIFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:cd03250   162 VGRHIFEnCILGLLLNNKTRILVTHQLQLLPHA-DQIVVLDNGR 204
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 34-226 4.55e-19

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 83.80  E-value: 4.55e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELGVGFNAELTARENV 112
Cdd:cd03246     8 FRYPGAEP-PVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGAdISQWDPNELGDHVGYLPQDDE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGAILglsrslvaerfDDIVrfselsdfmdqklknySSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVF 192
Cdd:cd03246    87 LFSGSIA-----------ENIL----------------SGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAI 139

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1671187127 193 RRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03246   140 AALKAAGATRIVIAHRPETLAS-ADRILVLEDGR 172
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
47-226 5.18e-19

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 86.78  E-value: 5.18e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  47 DVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPFIELGVG-------FNAELTARENVFLS 115
Cdd:PRK13537   25 GLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGepvpSRARHARQRVGvvpqfdnLDPDFTVRENLLVF 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF 195
Cdd:PRK13537  105 GRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSL 184

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 196 KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13537  185 LARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 44-226 8.54e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 85.43  E-value: 8.54e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLspfielgvgFNAE--LTARENVflsGAIL-- 119
Cdd:PRK13632   24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGIT---------ISKEnlKEIRKKI---GIIFqn 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 120 ----------------GL-SRSLVAERFDDIVRFS----ELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:PRK13632   92 pdnqfigatveddiafGLeNKKVPPKKMKDIIDDLakkvGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTS 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1671187127 179 VGDASFQEKCFDVFRRFKKEG-RTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:PRK13632  172 MLDPKGKREIKKIMVDLRKTRkKTLISITHDMDEAIL-ADKVIVFSEGK 219
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
43-231 1.12e-18

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 86.92  E-value: 1.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGL---------------LSPfielgvgf 102
Cdd:PRK09452   28 EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRImldgqDITHVpaenrhvntvfqsyaLFP-------- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 naELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:PRK09452  100 --HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDY 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 183 SFQEKCFDVFRRFKKE-GRTIIFVSHDmgsiQE----FSDRVLILNHGR------PRGIY 231
Cdd:PRK09452  178 KLRKQMQNELKALQRKlGITFVFVTHD----QEealtMSDRIVVMRDGRieqdgtPREIY 233
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 43-232 3.45e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 83.97  E-value: 3.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG---------LLSPFIELGVGF---NAEL---T 107
Cdd:PRK13639   16 EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGepikydkksLLEVRKTVGIVFqnpDDQLfapT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:PRK13639   96 VEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQ 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 188 CFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIYS 232
Cdd:PRK13639  176 IMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKiikegtPKEVFS 226
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 53-230 6.43e-18

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 81.96  E-value: 6.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  53 TRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL---------SPFIELGVGF---NAEL----TARENVflsg 116
Cdd:cd03297    21 LNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVlfdsrkkinLPPQQRKIGLvfqQYALfphlNVRENL---- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 117 aILGLSRSLVAErfdDIVRFSELSDFMD-QKLKNYSSGMLV-----RLAFAVAIQAHADILLVDEVLAVGDASFQEKCFD 190
Cdd:cd03297    97 -AFGLKRKRNRE---DRISVDELLDLLGlDHLLNRYPAQLSggekqRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1671187127 191 VFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGI 230
Cdd:cd03297   173 ELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYI 213
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 38-219 1.01e-17

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 84.73  E-value: 1.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllSPFIELGV-----GFNAELTARENV 112
Cdd:COG0488     9 GGRPL--LDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI----PKGLRIGYlpqepPLDDDLTVLDTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLS-GAILGLSRSL------VAERFDDIVRFSELSDFM--------------------------DQKLKNYSSGMLVRLA 159
Cdd:COG0488    83 LDGdAELRALEAELeeleakLAEPDEDLERLAELQEEFealggweaearaeeilsglgfpeedlDRPVSELSGGWRRRVA 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 160 FAVAIQAHADILLVDE---------V--LAvgdasfqekcfDVFRRFKKegrTIIFVSHDmgsiQEFSDRV 219
Cdd:COG0488   163 LARALLSEPDLLLLDEptnhldlesIewLE-----------EFLKNYPG---TVLVVSHD----RYFLDRV 215
cbiO PRK13644
energy-coupling factor transporter ATPase;
44-228 1.18e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 82.34  E-value: 1.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS------PFIELGVGF---NAEL-----TAR 109
Cdd:PRK13644   17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTgdfsklQGIRKLVGIvfqNPETqfvgrTVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:PRK13644   97 EDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVL 176

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHGRPR 228
Cdd:PRK13644  177 ERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIV 214
Wzt_C pfam14524
Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal ...
 268-391 1.75e-17

Wzt C-terminal domain; This domain is found at the C-terminus of the Wzt protein. The crystal structure of C-Wzt(O9a) reveals a beta sandwich with an immunoglobulin-like topology that contains the O-antigenic polysaccharide binding pocket. This domain is often associated with the ABC-transporter domain.


Pssm-ID: 464200  Cd Length: 141  Bit Score: 78.52  E-value: 1.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 268 RIVSVEMLDGNGQTTHAIQRGQSATIRLKIANPQR-EPVNAGVAIYRDDGLHCFGTNTVISHAAVP-TDAETVLLLDY-Q 344
Cdd:pfam14524   9 EIIDVELLDEDGKPTNTFESGEEVTLRIKVRFHEDvEDPIFGFTIKDRLGQEVFGTNTFLEGKSLGaLKAGEVVEVEFrF 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 345 CMDLQHGTYWLTVGLFG----GRLGTVYEMLERLYSFHIGQSDAYE--GVVYM 391
Cdd:pfam14524  89 KLNLQPGEYLLSVAIEDadgeQHEHVVYDWLDDALVFEVGVSSKNVfvGLVDL 141
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
51-269 4.31e-17

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 82.93  E-value: 4.31e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  51 EITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS--P-FIELgvgfNAELTAREnvFLSGailglsrslVA 127
Cdd:PRK13409  361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKISykPqYIKP----DYDGTVED--LLRS---------IT 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 128 ERFD------DIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GR 200
Cdd:PRK13409  426 DDLGssyyksEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEErEA 505

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 201 TIIFVSHDMGSIQEFSDRVLILNhGRPrGIYSPAGAAVEysrlNEEHANRLLS--------DSKaaptsatSSRPRI 269
Cdd:PRK13409  506 TALVVDHDIYMIDYISDRLMVFE-GEP-GKHGHASGPMD----MREGMNRFLKelgitfrrDEE-------TGRPRV 569
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
44-231 4.36e-17

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 82.19  E-value: 4.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPFIE-LGVGFNA-----ELTARENVF 113
Cdd:PRK11607   34 AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVdlshVPPYQRpINMMFQSyalfpHMTVEQNIA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 LSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC-FDVF 192
Cdd:PRK11607  114 FGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMqLEVV 193

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 193 RRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIY 231
Cdd:PRK11607  194 DILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKfvqigePEEIY 238
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 38-226 9.35e-17

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 79.43  E-value: 9.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPfIEL-----------GVGF 102
Cdd:PRK13548   13 GGRTL--LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRpladWSP-AELarrravlpqhsSLSF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 naELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFA-VAIQAHAD-----ILLVDEV 176
Cdd:PRK13548   90 --PFTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLArVLAQLWEPdgpprWLLLDEP 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 177 LAVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13548  168 TSALDLAHQHHVLRLARQLaHERGLAVIVVLHDLNLAARYADRIVLLHQGR 218
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 42-226 1.46e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 79.74  E-value: 1.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV----------SVTGLLSPFIE-------------- 97
Cdd:PRK13651   20 LKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkKKTKEKEKVLEklviqktrfkkikk 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  98 -------LGVGFN-AEL-----TARENVFLSGAILGLSRSLVAERFDDIVRFSELS-DFMDQKLKNYSSGMLVRLAFAVA 163
Cdd:PRK13651  100 ikeirrrVGVVFQfAEYqlfeqTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDeSYLQRSPFELSGGQKRRVALAGI 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 164 IQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13651  180 LAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGK 242
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
44-232 1.52e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 79.36  E-value: 1.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIE--------LGVGF---NAELTA---R 109
Cdd:PRK13633   25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEnlwdirnkAGMVFqnpDNQIVAtivE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:PRK13633  105 EDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVV 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1671187127 190 DVFRRF-KKEGRTIIFVSHDMGSIQEfSDRVLILNHGR------PRGIYS 232
Cdd:PRK13633  185 NTIKELnKKYGITIILITHYMEEAVE-ADRIIVMDSGKvvmegtPKEIFK 233
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
43-226 2.06e-16

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 78.90  E-value: 2.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV---------SVTGLLSPFIELGVGFNaelTARENVF 113
Cdd:PRK13638   15 PVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVlwqgkpldySKRGLLALRQQVATVFQ---DPEQQIF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 ---------LSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASF 184
Cdd:PRK13638   92 ytdidsdiaFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAG 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1671187127 185 QEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13638  172 RTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQ 213
cbiO PRK13646
energy-coupling factor transporter ATPase;
43-247 2.26e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 78.67  E-value: 2.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----------LSPF-IELGVGFNA------E 105
Cdd:PRK13646   21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDItithktkdkyIRPVrKRIGMVFQFpesqlfE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVFLSGAILGLSRSLVAER-FDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASF 184
Cdd:PRK13646  101 DTVEREIIFGPKNFKMNLDEVKNYaHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQS 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 185 QEKCFDVFRRFK-KEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAGAAVEYSRLNEEH 247
Cdd:PRK13646  181 KRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLADWH 244
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
43-229 2.83e-16

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 77.22  E-value: 2.83e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----LLS---PFI--ELGVGFN-----AELT 107
Cdd:PRK10908   16 QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGhditrLKNrevPFLrrQIGMIFQdhhllMDRT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRslvaerfDDIVRfsELSDFMDQ-----KLKNY----SSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:PRK10908   96 VYDNVAIPLIIAGASG-------DDIRR--RVSAALDKvglldKAKNFpiqlSGGEQQRVGIARAVVNKPAVLLADEPTG 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 179 VGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRG 229
Cdd:PRK10908  167 NLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHLHG 217
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 43-226 2.84e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 78.31  E-value: 2.84e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-------------------------LLSPFIE 97
Cdd:PRK13652   18 EALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGepitkenirevrkfvglvfqnpddqIFSPTVE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  98 LGVGFnaeltarenvflsGAI-LGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:PRK13652   98 QDIAF-------------GPInLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 177 LAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13652  165 TAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGR 215
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 34-226 3.23e-16

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 80.19  E-value: 3.23e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRrlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfIELG-------------V 100
Cdd:COG4988   344 FSYPGGR--PALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILING-----VDLSdldpaswrrqiawV 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 GFNAEL---TARENVFLSGAilGLSRSLVAE-----RFDDIVRfsELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHA 168
Cdd:COG4988   417 PQNPYLfagTIRENLRLGRP--DASDEELEAaleaaGLDEFVA--ALPDGLDTPLgeggRGLSGGQAQRLALARALLRDA 492

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 169 DILLVDEVLAVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIqEFSDRVLILNHGR 226
Cdd:COG4988   493 PLLLLDEPTAHLDAETEAEILQALRRLAK-GRTVILITHRLALL-AQADRILVLDDGR 548
cbiO PRK13650
energy-coupling factor transporter ATPase;
45-233 3.88e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 77.85  E-value: 3.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-LLSP------FIELGVGFNAEltarENVFLsGA 117
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGdLLTEenvwdiRHKIGMVFQNP----DNQFV-GA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 118 IL-----------GLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQE 186
Cdd:PRK13650   98 TVeddvafglenkGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRL 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 187 KCFDVFRRFKKE-GRTIIFVSHDMGSIQeFSDRVLILNHGRPRGIYSP 233
Cdd:PRK13650  178 ELIKTIKGIRDDyQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTP 224
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
47-233 3.94e-16

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 78.99  E-value: 3.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  47 DVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--------------------LLSPFIELGvgfnael 106
Cdd:PRK11432   24 NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGedvthrsiqqrdicmvfqsyALFPHMSLG------- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 tarENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA---- 182
Cdd:PRK11432   97 ---ENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDAnlrr 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 183 SFQEKCFDVFRRFkkeGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSP 233
Cdd:PRK11432  174 SMREKIRELQQQF---NITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSP 221
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 36-226 5.32e-16

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 76.70  E-value: 5.32e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  36 PAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELG--------VGFN--- 103
Cdd:COG4181    19 GTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQdLFALDEDArarlrarhVGFVfqs 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 ----AELTARENVFLSGAILGLSRSL-VAERFDDIVRFSELSDFMDQKLknysSG---MLVRLAFAVAIQahADILLVDE 175
Cdd:COG4181    99 fqllPTLTALENVMLPLELAGRRDARaRARALLERVGLGHRLDHYPAQL----SGgeqQRVALARAFATE--PAILFADE 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 176 VLAVGDASFQEKCFD-VFRRFKKEGRTIIFVSHDMgSIQEFSDRVLILNHGR 226
Cdd:COG4181   173 PTGNLDAATGEQIIDlLFELNRERGTTLVLVTHDP-ALAARCDRVLRLRAGR 223
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 45-207 6.13e-16

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 76.07  E-value: 6.13e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGV---------GFNAELTARENVFLS 115
Cdd:PRK13539   18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEachylghrnAMKPALTVAENLEFW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIvrfsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF 195
Cdd:PRK13539   98 AAFLGGEELDIAAALEAV----GLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAH 173

                         170
                  ....*....|..
gi 1671187127 196 KKEGRTIIFVSH 207
Cdd:PRK13539  174 LAQGGIVIAATH 185
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 51-269 6.53e-16

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 79.44  E-value: 6.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  51 EITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS--P-FIELgvgfNAELTAREnvFLSGAIlglsrslvA 127
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKISykPqYISP----DYDGTVEE--FLRSAN--------T 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 128 ERFD------DIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF-KKEGR 200
Cdd:COG1245   428 DDFGssyyktEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFaENRGK 507

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 201 TIIFVSHDMGSIQEFSDRVLILNhGRPrGIYSPAGAAVEysrlNEEHANRLLS--------DskaaptsATSSRPRI 269
Cdd:COG1245   508 TAMVVDHDIYLIDYISDRLMVFE-GEP-GVHGHASGPMD----MREGMNRFLKelgitfrrD-------EETGRPRI 571
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
41-225 8.71e-16

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 77.82  E-value: 8.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVS-----VTGLLSPfiELGVGF---NAELTARENV 112
Cdd:PRK10851   14 RTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRfhgtdVSRLHAR--DRKVGFvfqHYALFRHMTV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGAiLGLSRSLVAERFD------------DIVRFSELSDFMDQKLknySSGMLVRLAFAVAIQAHADILLVDEVLAVG 180
Cdd:PRK10851   92 FDNIA-FGLTVLPRRERPNaaaikakvtqllEMVQLAHLADRYPAQL---SGGQKQRVALARALAVEPQILLLDEPFGAL 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 181 DASFQEKCFDVFRRFKKEGR-TIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK10851  168 DAQVRKELRRWLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQG 213
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 45-226 8.72e-16

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 73.64  E-value: 8.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllSPFIELGvgfnaeltarenvflsgailglsrs 124
Cdd:cd03221    16 LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW----GSTVKIG------------------------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 125 lvaerfddivrfselsdFMDQklknYSSGMLVRLAFAVAIQAHADILLVDE---------VLAVGDAsfqekcfdvfrrF 195
Cdd:cd03221    67 -----------------YFEQ----LSGGEKMRLALAKLLLENPNLLLLDEptnhldlesIEALEEA------------L 113

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 196 KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03221   114 KEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
45-226 1.08e-15

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 75.90  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL--LSP-----FIELGVG-----FN--AELTARE 110
Cdd:PRK09493   17 LHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLkvNDPkvderLIRQEAGmvfqqFYlfPHLTALE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NV-FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:PRK09493   97 NVmFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPELRHEVL 176

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK09493  177 KVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGR 213
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 44-226 1.78e-15

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 74.01  E-value: 1.78e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSP--FIELGVGFNAELTARENVFLSGA 117
Cdd:cd03215    15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGkpvtRRSPrdAIRAGIAYVPEDRKREGLVLDLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 118 I---LGLSRSLvaerfddivrfselsdfmdqklknySSGMLVRLAFAVAIQAHADILLVDEVlAVG-DASFQEKCFDVFR 193
Cdd:cd03215    95 VaenIALSSLL-------------------------SGGNQQKVVLARWLARDPRVLILDEP-TRGvDVGAKAEIYRLIR 148

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1671187127 194 RFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03215   149 ELADAGKAVLLISSELDELLGLCDRILVMYEGR 181
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 7-226 1.88e-15

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 75.89  E-value: 1.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRV--PLERTtslkqlaargfrpagsrrleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSG 84
Cdd:COG1101     2 LELKNLSKTFNPgtVNEKR--------------------ALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSG 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  85 RVS-----VTGL----LSPFIelG-------VGFNAELTARENVFLS---GAILGLSRSLVAERFDdivRFSE------- 138
Cdd:COG1101    62 SILidgkdVTKLpeykRAKYI--GrvfqdpmMGTAPSMTIEENLALAyrrGKRRGLRRGLTKKRRE---LFREllatlgl 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 139 -LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGR-TIIFVSHDMGSIQEFS 216
Cdd:COG1101   137 gLENRLDTKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNlTTLMVTHNMEQALDYG 216

                         250
                  ....*....|
gi 1671187127 217 DRVLILNHGR 226
Cdd:COG1101   217 NRLIMMHEGR 226
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 51-227 2.36e-15

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 75.14  E-value: 2.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  51 EITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGVGFNAELTAREnvFLSGAILGLSRSLVAErf 130
Cdd:cd03237    21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIKADYEGTVRD--LLSSITKDFYTHPYFK-- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 131 DDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDM 209
Cdd:cd03237    97 TEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFaENNEKTAFVVEHDI 176

                         170
                  ....*....|....*...
gi 1671187127 210 GSIQEFSDRVLILNhGRP 227
Cdd:cd03237   177 IMIDYLADRLIVFE-GEP 193
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 44-226 2.85e-15

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 74.57  E-value: 2.85e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG------------------LLSPFIelgvgFNAe 105
Cdd:cd03254    18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGidirdisrkslrsmigvvLQDTFL-----FSG- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 lTARENVFLSGaiLGLSRSLVAE-----RFDDIVRFSE--LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:cd03254    92 -TIMENIRLGR--PNATDEEVIEaakeaGAHDFIMKLPngYDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATS 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 179 VGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQeFSDRVLILNHGR 226
Cdd:cd03254   169 NIDTETEKLIQEALEKLMK-GRTSIIIAHRLSTIK-NADKILVLDDGK 214
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 42-234 3.43e-15

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 74.64  E-value: 3.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGLLSPFI-ELGV--GFN-----AELTA 108
Cdd:PRK11300   18 LLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTIllrgqHIEGLPGHQIaRMGVvrTFQhvrlfREMTV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 109 RENVFL-------SGAILGL-----SRSLVAERFDDIVRFSE---LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLV 173
Cdd:PRK11300   98 IENLLVaqhqqlkTGLFSGLlktpaFRRAESEALDRAATWLErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 174 DEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPA 234
Cdd:PRK11300  178 DEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPE 239
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
46-226 4.00e-15

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 76.22  E-value: 4.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  46 QDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS---PFIELGVG--FNA-----ELTARENVFLS 115
Cdd:PRK11000   20 KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMndvPPAERGVGmvFQSyalypHLSVAENMSFG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC-FDVFRR 194
Cdd:PRK11000  100 LKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMrIEISRL 179

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1671187127 195 FKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11000  180 HKRLGRTMIYVTHDQVEAMTLADKIVVLDAGR 211
cbiO PRK13649
energy-coupling factor transporter ATPase;
44-226 4.34e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 75.17  E-value: 4.34e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV--------------------TGLLSPFIELGVgfn 103
Cdd:PRK13649   22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVddtlitstsknkdikqirkkVGLVFQFPESQL--- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILGLSR----SLVAERFdDIVRFSElsDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:PRK13649   99 FEETVLKDVAFGPQNFGVSQeeaeALAREKL-ALVGISE--SLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13649  176 LDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGK 222
cbiO PRK13643
energy-coupling factor transporter ATPase;
36-225 4.58e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 75.16  E-value: 4.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  36 PAGSRrleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----------LSPF-IELGVGFN- 103
Cdd:PRK13643   16 PFASR---ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIvvsstskqkeIKPVrKKVGVVFQf 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 -----AELTARENVFLSGAILGLSRS----LVAERFdDIVRFSElsDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVD 174
Cdd:PRK13643   93 pesqlFEETVLKDVAFGPQNFGIPKEkaekIAAEKL-EMVGLAD--EFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLD 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 175 EVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK13643  170 EPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKG 220
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 7-226 5.87e-15

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 75.09  E-value: 5.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPlerttslkqlaargfrpagSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRP---TS 83
Cdd:COG0444     2 LEVRNLKVYFPTR-------------------RGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTS 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVTGllspfIELgvgfnAELTAREN----------VF---LS--------GAIL--------GLSRS----LVAERF 130
Cdd:COG0444    63 GEILFDG-----EDL-----LKLSEKELrkirgreiqmIFqdpMTslnpvmtvGDQIaeplrihgGLSKAeareRAIELL 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 131 DDiVRFSELSDFMDQklknY----SSGMLVRLAFAVAIQAHADILLVDE-VLAVgDASFQEKCFDVFRRFKKE-GRTIIF 204
Cdd:COG0444   133 ER-VGLPDPERRLDR----YphelSGGMRQRVMIARALALEPKLLIADEpTTAL-DVTIQAQILNLLKDLQRElGLAILF 206

                         250       260
                  ....*....|....*....|..
gi 1671187127 205 VSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG0444   207 ITHDLGVVAEIADRVAVMYAGR 228
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
37-226 6.11e-15

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 74.00  E-value: 6.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  37 AGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPfIEL-----------GVG 101
Cdd:COG4559    11 LGGRTL--LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRplaaWSP-WELarrravlpqhsSLA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 102 FNaeLTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQklkNYSSgmL-------VRLAFAVAiQAHAD----- 169
Cdd:COG4559    88 FP--FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGR---SYQT--LsggeqqrVQLARVLA-QLWEPvdggp 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 170 -ILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4559   160 rWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGR 217
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 45-234 7.38e-15

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 75.65  E-value: 7.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----LLSPFIELGVGFNAELTARENVFLSGAIL 119
Cdd:PRK09536   19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGddveaLSARAASRRVASVPQDTSLSFEFDVRQVV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 120 GLSRSLVAERFDDI-----------VRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:PRK09536   99 EMGRTPHRSRFDTWtetdraaveraMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDINHQVRT 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 189 FDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPA 234
Cdd:PRK09536  179 LELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPA 224
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 38-226 7.74e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 75.87  E-value: 7.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSvtglLSPFIELGV------GFNAELTAREN 111
Cdd:COG0488   326 GDKTL--LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVK----LGETVKIGYfdqhqeELDPDKTVLDE 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 V--FLSGAILGLSRSLVaERFDdivrFSelSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE-----------VLA 178
Cdd:COG0488   400 LrdGAPGGTEQEVRGYL-GRFL----FS--GDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEptnhldietleALE 472

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 179 VGDASFqekcfdvfrrfkkEGrTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG0488   473 EALDDF-------------PG-TVLLVSHDRYFLDRVATRILEFEDGG 506
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 43-226 8.72e-15

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 73.29  E-value: 8.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfIELGVGFNAELTA------RENVFLSG 116
Cdd:cd03252    16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDG-----HDLALADPAWLRRqvgvvlQENVLFNR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 117 AI---LGLSR-SLVAERFDDIVRFSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:cd03252    91 SIrdnIALADpGMSMERVIEAAKLAGAHDFISELPEGYdtivgeqgaglSGGQRQRIAIARALIHNPRILIFDEATSALD 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 182 ASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03252   171 YESEHAIMRNMHDICA-GRTVIIIAHRLSTVKN-ADRIIVMEKGR 213
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 43-226 1.10e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 73.73  E-value: 1.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV---------SVTGLLSPFIELGVGF----NAELTAR 109
Cdd:PRK13636   20 HALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRIlfdgkpidySRKGLMKLRESVGMVFqdpdNQLFSAS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 --ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:PRK13636  100 vyQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSE 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1671187127 188 CFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13636  180 IMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGR 219
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
45-226 1.10e-14

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 73.51  E-value: 1.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPFielgVGFNAELTARENVFLSGAIL---GL 121
Cdd:PRK11231   18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGD--KPI----SMLSSRQLARRLALLPQHHLtpeGI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 122 S-RSLVA------------------ERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:PRK11231   92 TvRELVAygrspwlslwgrlsaednARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDI 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1671187127 183 SFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11231  172 NHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGH 215
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
44-233 1.20e-14

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 75.07  E-value: 1.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI-----------ELGVGFNA-----ELT 107
Cdd:PRK10070   43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKIsdaelrevrrkKIAMVFQSfalmpHMT 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:PRK10070  123 VLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 188 CFDVFRRFK-KEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSP 233
Cdd:PRK10070  203 MQDELVKLQaKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
37-226 1.47e-14

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 73.18  E-value: 1.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  37 AGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELGVG---------FNAEL 106
Cdd:PRK10419   20 GKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEpLAKLNRAQRKafrrdiqmvFQDSI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVFLSGAILG--------LSRSLVAERFDDIVRFSELSDFMDQKL-KNYSSGMLVRLAFAVAIQAHADILLVDEVL 177
Cdd:PRK10419  100 SAVNPRKTVREIIReplrhllsLDKAERLARASEMLRAVDLDDSVLDKRpPQLSGGQLQRVCLARALAVEPKLLILDEAV 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1671187127 178 AVGDASFQEKCFDVFRRFKKEGRT-IIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10419  180 SNLDLVLQAGVIRLLKKLQQQFGTaCLFITHDLRLVERFCQRVMVMDNGQ 229
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 47-226 1.93e-14

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 71.76  E-value: 1.93e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  47 DVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL---LSPFIELGVG--FN-----AELTARENVflsg 116
Cdd:cd03298    16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVdvtAAPPADRPVSmlFQennlfAHLTVEQNV---- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 117 aILGLSRSLV-----AERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDV 191
Cdd:cd03298    92 -GLGLSPGLKltaedRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDL 170

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 192 FRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:cd03298   171 VLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 44-225 3.21e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 72.09  E-value: 3.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL---SPFIELGVGFNAELTARENVFLsGAIL- 119
Cdd:PRK13648   24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAitdDNFEKLRKHIGIVFQNPDNQFV-GSIVk 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 120 -----GLSRSLVA-----ERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:PRK13648  103 ydvafGLENHAVPydemhRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLL 182

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 190 DVFRRFKKEGR-TIIFVSHDMGSIQEfSDRVLILNHG 225
Cdd:PRK13648  183 DLVRKVKSEHNiTIISITHDLSEAME-ADHVIVMNKG 218
cbiO PRK13640
energy-coupling factor transporter ATPase;
44-232 4.81e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 71.75  E-value: 4.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllspFIELGVGFNAELT--ARENV--------- 112
Cdd:PRK13640   22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSK------ITVDGITLTAKTVwdIREKVgivfqnpdn 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 -FLSGAI-----LGL-SRSLVAERFDDIVR--FSE--LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:PRK13640   96 qFVGATVgddvaFGLeNRAVPRPEMIKIVRdvLADvgMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLD 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 182 ASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSiQEFSDRVLILNHGR------PRGIYS 232
Cdd:PRK13640  176 PAGKEQILKLIRKLKKKnNLTVISITHDIDE-ANMADQVLVLDDGKllaqgsPVEIFS 232
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 26-226 7.30e-14

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 70.73  E-value: 7.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  26 LKQLAARGfrpagsrRLEALqdvSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPTSGRVSVTG-LLSPFIElgvgfnA 104
Cdd:PRK03695    3 LNDVAVST-------RLGPL---SAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGqPLEAWSA------A 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 105 ELtARENVFLS---------------------GAILGLSRSLVaerfDDIVRFSELSDFMDQKLKNYSSG--MLVRLAfA 161
Cdd:PRK03695   66 EL-ARHRAYLSqqqtppfampvfqyltlhqpdKTRTEAVASAL----NEVAEALGLDDKLGRSVNQLSGGewQRVRLA-A 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 162 VAIQAHADI------LLVDEVLAVGDASfQEKCFD-VFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK03695  140 VVLQVWPDInpagqlLLLDEPMNSLDVA-QQAALDrLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGK 210
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
43-226 1.30e-13

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 70.38  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI-----ELGVG---------------- 101
Cdd:PRK10619   19 EVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVrdkdgQLKVAdknqlrllrtrltmvf 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 102 --FN--AELTARENVFLSGA-ILGLSRSLVAERfddIVRFSELSDFMDQKLKNY----SSGMLVRLAFAVAIQAHADILL 172
Cdd:PRK10619   99 qhFNlwSHMTVLENVMEAPIqVLGLSKQEARER---AVKYLAKVGIDERAQGKYpvhlSGGQQQRVSIARALAMEPEVLL 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 173 VDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10619  176 FDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGK 229
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
44-217 1.68e-13

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 70.30  E-value: 1.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL---------LSPFI----ELGVGFNAELtarE 110
Cdd:PRK15056   22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQptrqalqknLVAYVpqseEVDWSFPVLV---E 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLSGAI--LGLSRSLVA---ERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ 185
Cdd:PRK15056   99 DVVMMGRYghMGWLRRAKKrdrQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTE 178

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1671187127 186 EKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSD 217
Cdd:PRK15056  179 ARIISLLRELRDEGKTMLVSTHNLGSVTEFCD 210
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 24-222 2.23e-13

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 68.97  E-value: 2.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  24 TSLKQLAARGFRpAGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPFI-EL 98
Cdd:PRK10247    5 SPLLQLQNVGYL-AGDAKI--LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGedisTLKPEIyRQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  99 GVGFNAEL------TARENVFLSGAILGLSRSLVAERfDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILL 172
Cdd:PRK10247   82 QVSYCAQTptlfgdTVYDNLIFPWQIRNQQPDPAIFL-DDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 173 VDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEfSDRVLIL 222
Cdd:PRK10247  161 LDEITSALDESNKHNVNEIIHRYVREqNIAVLWVTHDKDEINH-ADKVITL 210
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 45-226 3.35e-13

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 69.01  E-value: 3.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELG------------VGF---NAEL-- 106
Cdd:PRK11264   19 LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDItIDTARSLSqqkglirqlrqhVGFvfqNFNLfp 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 --TARENVFLSGAIL-GLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDAS 183
Cdd:PRK11264   99 hrTVLENIIEGPVIVkGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPE 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 184 FQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11264  179 LVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGR 221
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 25-207 3.95e-13

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 67.77  E-value: 3.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  25 SLKQLA-ARGFRPAgsrrleaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIE------ 97
Cdd:TIGR01189   2 AARNLAcSRGERML-------FEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRdephen 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  98 ---LG--VGFNAELTARENVFLSGAILGLSRSLVAERFDDIvrfsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILL 172
Cdd:TIGR01189  75 ilyLGhlPGLKPELSALENLHFWAAIHGGAQRTIEDALAAV----GLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWI 150

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1671187127 173 VDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSH 207
Cdd:TIGR01189 151 LDEPTTALDKAGVALLAGLLRAHLARGGIVLLTTH 185
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
36-245 4.02e-13

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 70.91  E-value: 4.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  36 PAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL---------LSPFIELGVGFN--- 103
Cdd:PRK10535   15 PSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQdvatldadaLAQLRREHFGFIfqr 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 ----AELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:PRK10535   95 yhllSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 180 GDASFQEKCFDVFRRFKKEGRTIIFVSHDmGSIQEFSDRVLILNHGR----PRGIYSPAGAAVEYSRLNE 245
Cdd:PRK10535  175 LDSHSGEEVMAILHQLRDRGHTVIIVTHD-PQVAAQAERVIEIRDGEivrnPPAQEKVNVAGGTEPVVNT 243
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 35-239 4.35e-13

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 70.42  E-value: 4.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  35 RPAGSRRLE-------ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPFIELGVGFn 103
Cdd:PRK10762  251 KAPGEVRLKvdnlsgpGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGhevvTRSPQDGLANGI- 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 aeltarenVFLS------GAILGLS----RSLVAERF-----------------DDIVR-FSELSDFMDQKLKNYSSGML 155
Cdd:PRK10762  330 --------VYISedrkrdGLVLGMSvkenMSLTALRYfsraggslkhadeqqavSDFIRlFNIKTPSMEQAIGLLSGGNQ 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 156 VRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSPAG 235
Cdd:PRK10762  402 QKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRISGEFTREQ 481


                  ....
gi 1671187127 236 AAVE 239
Cdd:PRK10762  482 ATQE 485
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 34-226 5.35e-13

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 70.55  E-value: 5.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRLeALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG---------LLSPFIelgvGF-- 102
Cdd:COG4618   338 VVPPGSKRP-ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGadlsqwdreELGRHI----GYlp 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 -NAEL---TARENvflsgailglsrslvaerfddIVRFSELSDF-------------MDQKLKN-Y-----------SSG 153
Cdd:COG4618   413 qDVELfdgTIAEN---------------------IARFGDADPEkvvaaaklagvheMILRLPDgYdtrigeggarlSGG 471

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 154 MLVRLAFAVAIQAHADILLVDE----VLAVGDASFQEkcfdVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:COG4618   472 QRQRIGLARALYGDPRLVVLDEpnsnLDDEGEAALAA----AIRALKARGATVVVITHRPSLLAA-VDKLLVLRDGR 543
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 44-226 5.85e-13

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 70.39  E-value: 5.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfielgvgfnAELTArenvflsgAILGLSR 123
Cdd:PRK10522  338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDG-------------KPVTA--------EQPEDYR 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 124 SLVAERFDDIVRFSELSD------------------FMDQKLK---------NYSSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:PRK10522  397 KLFSAVFTDFHLFDQLLGpegkpanpalvekwlerlKMAHKLEledgrisnlKLSKGQKKRLALLLALAEERDILLLDEW 476

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 177 LAVGDAsfqekcfdVFRRF---------KKEGRTIIFVSHDmGSIQEFSDRVLILNHGR 226
Cdd:PRK10522  477 AADQDP--------HFRREfyqvllpllQEMGKTIFAISHD-DHYFIHADRLLEMRNGQ 526
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 62-176 7.13e-13

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 66.82  E-value: 7.13e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  62 GPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGLLSPF---IELGVGFNAELTARENVFLSGAILGLSRSLVAErfddi 133
Cdd:PRK13541   33 GANGCGKSSLLRMIAGIMQPSSGNIyykncNINNIAKPYctyIGHNLGLKLEMTVFENLKFWSEIYNSAETLYAA----- 107

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 134 VRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:PRK13541  108 IHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEV 150
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 1-226 7.73e-13

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 67.46  E-value: 7.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   1 MQTdvAISIEHLTKVFRvplerttsLKQLaargfrpaGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYR 80
Cdd:COG4778     1 MTT--LLEVENLSKTFT--------LHLQ--------GGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYL 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  81 PTSGRVSVTGLLSPfIELgvgfnAELTAREnvflsgaILGLSRS-------------------LVAE--------RFDDI 133
Cdd:COG4778    63 PDSGSILVRHDGGW-VDL-----AQASPRE-------ILALRRRtigyvsqflrviprvsaldVVAEpllergvdREEAR 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 134 VRFSELSDFM--DQKL-----KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVS 206
Cdd:COG4778   130 ARARELLARLnlPERLwdlppATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIF 209

                         250       260
                  ....*....|....*....|
gi 1671187127 207 HDMGSIQEFSDRVLILNHGR 226
Cdd:COG4778   210 HDEEVREAVADRVVDVTPFS 229
cbiO PRK13642
energy-coupling factor transporter ATPase;
45-225 9.92e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 68.20  E-value: 9.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--LLSPFI-----ELGVGFN------AELTAREN 111
Cdd:PRK13642   23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGelLTAENVwnlrrKIGMVFQnpdnqfVGATVEDD 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDV 191
Cdd:PRK13642  103 VAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRV 182

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1671187127 192 FRRFK-KEGRTIIFVSHDMGSIQEfSDRVLILNHG 225
Cdd:PRK13642  183 IHEIKeKYQLTVLSITHDLDEAAS-SDRILVMKAG 216
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 44-226 1.14e-12

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 65.80  E-value: 1.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfielgvgfnAELTARENVfLSGAILGLSR 123
Cdd:cd03247    17 VLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDG-------------VPVSDLEKA-LSSLISVLNQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 124 SlvAERFDDIVRfselsdfmdQKL-KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEgRTI 202
Cdd:cd03247    83 R--PYLFDTTLR---------NNLgRRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVLKD-KTL 150

                         170       180
                  ....*....|....*....|....
gi 1671187127 203 IFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:cd03247   151 IWITHHLTGIEHM-DKILFLENGK 173
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
44-209 1.18e-12

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 67.42  E-value: 1.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--LLSPFIELGVGFNAE-----LTARENVFLSG 116
Cdd:PRK11248   16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGkpVEGPGAERGVVFQNEgllpwRNVQDNVAFGL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 117 AILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA----SFQEKCFDVF 192
Cdd:PRK11248   96 QLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAftreQMQTLLLKLW 175

                         170
                  ....*....|....*..
gi 1671187127 193 RRfkkEGRTIIFVSHDM 209
Cdd:PRK11248  176 QE---TGKQVLLITHDI 189
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
49-226 1.22e-12

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 67.09  E-value: 1.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  49 SIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGLLS---PFIELgvgFN-----AELTARENVFls 115
Cdd:COG3840    19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRIlwngqDLTALPPaerPVSML---FQennlfPHLTVAQNIG-- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 gaiLGLSRSL---VAER--FDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFD 190
Cdd:COG3840    94 ---LGLRPGLkltAEQRaqVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLD 170

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 191 VFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG3840   171 LVDELCRErGLTVLMVTHDPEDAARIADRVLLVADGR 207
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 55-231 1.52e-12

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 67.01  E-value: 1.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  55 GEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV----SVTGLLSPF--IELGVGF----NAELTARE---------NVFLS 115
Cdd:cd03236    26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppDWDEILDEFrgSELQNYFtkllEGDVKVIVkpqyvdlipKAVKG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 GAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF 195
Cdd:cd03236   106 KVGELLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLIREL 185

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 196 KKEGRTIIFVSHDMGSIQEFSDRVLILnHGRPrGIY 231
Cdd:cd03236   186 AEDDNYVLVVEHDLAVLDYLSDYIHCL-YGEP-GAY 219
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 34-226 1.65e-12

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 69.66  E-value: 1.65e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   34 FRPAGSrrlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV------TGLLSPFIELG------VG 101
Cdd:TIGR01257  938 FEPSGR---PAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVggkdieTNLDAVRQSLGmcpqhnIL 1014

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  102 FNaELTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:TIGR01257 1015 FH-HLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVD 1093

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1671187127  182 ASFQEKCFDVFRRFKkEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:TIGR01257 1094 PYSRRSIWDLLLKYR-SGRTIIMSTHHMDEADLLGDRIAIISQGR 1137
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 34-226 2.05e-12

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 68.64  E-value: 2.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV----------------SVTGLLS--PF 95
Cdd:COG4987   341 FRYPGAGR-PVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSItlggvdlrdldeddlrRRIAVVPqrPH 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  96 IelgvgFNAelTARENVflsgailglsrSLVAERFDD--------IVRFSELSDFMDQKL--------KNYSSGMLVRLA 159
Cdd:COG4987   420 L-----FDT--TLRENL-----------RLARPDATDeelwaaleRVGLGDWLAALPDGLdtwlgeggRRLSGGERRRLA 481

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 160 FAVAIQAHADILLVDE------------VLAvgdasfqekcfDVFRRFKkeGRTIIFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:COG4987   482 LARALLRDAPILLLDEptegldaateqaLLA-----------DLLEALA--GRTVLLITHRLAGLERM-DRILVLEDGR 546
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
43-226 2.81e-12

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 68.27  E-value: 2.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLS--------PFIelgvgFNA 104
Cdd:COG1132   354 PVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGvdirdltlesLRRqigvvpqdTFL-----FSG 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 105 elTARENVFLsgAILGLSRSLVAE-----RFDDIVRfsELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:COG1132   429 --TIRENIRY--GRPDATDEEVEEaakaaQAHEFIE--ALPDGYDTVVgergVNLSGGQRQRIAIARALLKDPPILILDE 502

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 176 VLAVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:COG1132   503 ATSALDTETEALIQEALERLMK-GRTTIVIAHRLSTIRN-ADRILVLDDGR 551
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 39-226 2.98e-12

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 68.34  E-value: 2.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  39 SRRLEALQDVSIEITRGEFFSVIGPNGSGKS-TLLKIMAGIYRpTSGRVSVTGLL-----SPFIELG------------- 99
Cdd:PRK10261   26 QQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQ-AGGLVQCDKMLlrrrsRQVIELSeqsaaqmrhvrga 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 100 ---VGFNAELTARENVFLSGAIL--------GLSRS---LVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQ 165
Cdd:PRK10261  105 dmaMIFQEPMTSLNPVFTVGEQIaesirlhqGASREeamVEAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVMIAMALS 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 166 AHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10261  185 CRPAVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVLVMYQGE 246
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 45-226 3.19e-12

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 66.02  E-value: 3.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPTSGRVSVTGL----LSPfielgvgfnAELtARENVFLS----- 115
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRplsdWSA---------AEL-ARHRAYLSqqqsp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 -GAI-------LGLSRSLVAE----RFDDIVRFSELSDFMDQKLKNYSSG--MLVRLAfAVAIQAHADI------LLVDE 175
Cdd:COG4138    81 pFAMpvfqylaLHQPAGASSEaveqLLAQLAEALGLEDKLSRPLTQLSGGewQRVRLA-AVLLQVWPTInpegqlLLLDE 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 176 VLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4138   160 PMNSLDVAQQAALDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGK 210
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 48-238 3.47e-12

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 67.90  E-value: 3.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  48 VSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfielgvgfnAELTA------REN---VF----L 114
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDG-------------QPVTAdnreayRQLfsaVFsdfhL 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 115 SGAILGLSRSLVAERFDDIVRFSELSD---FMDQKL--KNYSSGMLVRLAFAVAIQAHADILLVDEVlavgdASFQekcf 189
Cdd:COG4615   418 FDRLLGLDGEADPARARELLERLELDHkvsVEDGRFstTDLSQGQRKRLALLVALLEDRPILVFDEW-----AADQ---- 488

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 190 D-VFRRF---------KKEGRTIIFVSHDMgsiQEFS--DRVLILNHGRPRGIYSPAGAAV 238
Cdd:COG4615   489 DpEFRRVfytellpelKARGKTVIAISHDD---RYFDlaDRVLKMDYGKLVELTGPAALAA 546
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 45-226 3.91e-12

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 65.87  E-value: 3.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL---SPFIELG---------VGFNAELTAREnv 112
Cdd:COG4604    17 LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDvatTPSRELAkrlailrqeNHINSRLTVRE-- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 flsgailglsrsLVA-ERF---------------DDIVRFSELSDFMDQKLKNYSSGMLVRlAF-AVAIQAHADILLVDE 175
Cdd:COG4604    95 ------------LVAfGRFpyskgrltaedreiiDEAIAYLDLEDLADRYLDELSGGQRQR-AFiAMVLAQDTDYVLLDE 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 176 VL-------AVGdasfqekCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4604   162 PLnnldmkhSVQ-------MMKLLRRLADElGKTVVIVLHDINFASCYADHIVAMKDGR 213
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 45-207 4.04e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 64.97  E-value: 4.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSP-----------FIELGVGFNAELTARENVF 113
Cdd:PRK13540   17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKkdlctyqkqlcFVGHRSGINPYLTLRENCL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 LSgailgLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFR 193
Cdd:PRK13540   97 YD-----IHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQ 171

                         170
                  ....*....|....
gi 1671187127 194 RFKKEGRTIIFVSH 207
Cdd:PRK13540  172 EHRAKGGAVLLTSH 185
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 29-222 4.65e-12

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 64.82  E-value: 4.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFrpAGSRRLEAL-QDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGV------- 100
Cdd:cd03231     1 LEADEL--TCERDGRALfSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIargllyl 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 ----GFNAELTARENVFLSGAIlgLSRSLVAERFDDIvrfsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEV 176
Cdd:cd03231    79 ghapGIKTTLSVLENLRFWHAD--HSDEQVEEALARV----GLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEP 152

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 177 LAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLIL 222
Cdd:cd03231   153 TTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAGARELDL 198
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
29-239 5.12e-12

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 67.35  E-value: 5.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFRPAGsrrleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSPF--IELGVGF 102
Cdd:COG1129   257 LEVEGLSVGG-----VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpvrIRSPRdaIRAGIAY 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 ----------NAELTARENVFLsgAILG-------LSRSLVAERFDDIVRfsEL----SDfMDQKLKNYSSGMLVRLAFA 161
Cdd:COG1129   332 vpedrkgeglVLDLSIRENITL--ASLDrlsrgglLDRRRERALAEEYIK--RLriktPS-PEQPVGNLSGGNQQKVVLA 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 162 VAIQAHADILLVDE------VLAvgdasfqeKcFDVF---RRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYS 232
Cdd:COG1129   407 KWLATDPKVLILDEptrgidVGA--------K-AEIYrliRELAAEGKAVIVISSELPELLGLSDRILVMREGRIVGELD 477


                  ....*..
gi 1671187127 233 PAGAAVE 239
Cdd:COG1129   478 REEATEE 484
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
41-226 6.00e-12

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 64.90  E-value: 6.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLSPFIEL---GVGFNAELT 107
Cdd:PRK11614   17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGkditdwqtakIMREAVAIvpeGRRVFSRMT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAIlgLSRSLVAERFDDIVR-FSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE-VLAVGDASFQ 185
Cdd:PRK11614   97 VEENLAMGGFF--AERDQFQERIKWVYElFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEpSLGLAPIIIQ 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1671187127 186 EkCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11614  175 Q-IFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGH 214
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 29-239 6.98e-12

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 66.97  E-value: 6.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSP--FIELGVGF 102
Cdd:COG3845   258 LEVENLSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGeditGLSPreRRRLGVAY 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 103 ----------NAELTARENVFLS---------------GAILGLSRSLVaERFDdiVRFSELsdfmDQKLKNYSSGMLVR 157
Cdd:COG3845   338 ipedrlgrglVPDMSVAENLILGryrrppfsrggfldrKAIRAFAEELI-EEFD--VRTPGP----DTPARSLSGGNQQK 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 158 LAFAVAIQAHADILL-------VDevlaVGDASFqekcfdVFRRF---KKEGRTIIFVSHDMGSIQEFSDRVLILNHGRP 227
Cdd:COG3845   411 VILARELSRDPKLLIaaqptrgLD----VGAIEF------IHQRLlelRDAGAAVLLISEDLDEILALSDRIAVMYEGRI 480

                         250
                  ....*....|..
gi 1671187127 228 RGIYSPAGAAVE 239
Cdd:COG3845   481 VGEVPAAEATRE 492
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 44-232 9.07e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 65.43  E-value: 9.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV--------------------TGLLSPF-------- 95
Cdd:PRK13634   22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitagkknkklkplrkkVGIVFQFpehqlfee 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  96 -IELGVGF----------NAELTARENVFLsgaiLGLSRSLVAErfddivrfselSDFmdqklkNYSSGMLVRLAFAVAI 164
Cdd:PRK13634  102 tVEKDICFgpmnfgvseeDAKQKAREMIEL----VGLPEELLAR-----------SPF------ELSGGQMRRVAIAGVL 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 165 QAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVL------ILNHGRPRGIYS 232
Cdd:PRK13634  161 AMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEkGLTTVLVTHSMEDAARYADQIVvmhkgtVFLQGTPREIFA 235
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 43-226 9.39e-12

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 64.65  E-value: 9.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI-------------ELGVGFN-----A 104
Cdd:PRK11124   16 QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSktpsdkairelrrNVGMVFQqynlwP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 105 ELTARENvfLSGA---ILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:PRK11124   96 HLTVQQN--LIEApcrVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALD 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 182 ASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11124  174 PEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGH 218
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 43-208 1.09e-11

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 66.23  E-value: 1.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----LLSPFIELGVGFNAE------LTAREN 111
Cdd:TIGR02868 349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGvpvssLDQDEVRRRVSVCAQdahlfdTTVREN 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFL-----SGAilGLSRSLVAERFDDIVRfsELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:TIGR02868 429 LRLarpdaTDE--ELWAALERVGLADWLR--ALPDGLDTVLgeggARLSGGERQRLALARALLADAPILLLDEPTEHLDA 504

                         170       180       190
                  ....*....|....*....|....*....|
gi 1671187127 183 ----SFQEKCFDVfrrfkKEGRTIIFVSHD 208
Cdd:TIGR02868 505 etadELLEDLLAA-----LSGRTVVLITHH 529
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 41-222 1.51e-11

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 65.77  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELG-------VGFNAELTA---R 109
Cdd:TIGR02857 334 RRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVpLADADADSwrdqiawVPQHPFLFAgtiA 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLS---GAILGLSRSLVAERFDDIVrfSELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:TIGR02857 414 ENIRLArpdASDAEIREALERAGLDEFV--AALPQGLDTPIgeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDA 491

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1671187127 183 SFQEKCFDVFRRFkKEGRTIIFVSHDMGSIqEFSDRVLIL 222
Cdd:TIGR02857 492 ETEAEVLEALRAL-AQGRTVLLVTHRLALA-ALADRIVVL 529
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 45-231 1.63e-11

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 62.95  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAG--IYRPTSGRVSVTGLLSPFIELG--VGF-------NAELTARENvf 113
Cdd:cd03213    25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRkiIGYvpqddilHPTLTVRET-- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 lsgailglsrslvaerfddiVRFSelsdfmdQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFR 193
Cdd:cd03213   103 --------------------LMFA-------AKLRGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR 155

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 194 RFKKEGRTIIFVSHD-MGSIQEFSDRVLILNHGRPrgIY 231
Cdd:cd03213   156 RLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRV--IY 192
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 27-226 1.70e-11

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 63.95  E-value: 1.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  27 KQLAARGFRPAGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKS----TLLKIMAGIYRPTSGRVSVTGL-LSPFIELGV- 100
Cdd:PRK10418    3 QQIELRNIALQAAQPL--VHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKpVAPCALRGRk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 ----------GFNAELTARENVFLSGAILG-------LSRSLVAERFDDIVRFSELSDFmdqklkNYSSGMLVRLAFAVA 163
Cdd:PRK10418   81 iatimqnprsAFNPLHTMHTHARETCLALGkpaddatLTAALEAVGLENAARVLKLYPF------EMSGGMLQRMMIALA 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 164 IQAHADILLVDEVLAVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10418  155 LLCEAPFIIADEPTTDLDVVAQARILDLLESIvQKRALGMLLVTHDMGVVARLADDVAVMSHGR 218
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 45-232 1.71e-11

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 63.44  E-value: 1.71e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRP---TSGRVSVTGL-LSP--------FIELGVGFNAELTARENV 112
Cdd:cd03234    23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNGQpRKPdqfqkcvaYVRQDDILLPGLTVRETL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSgAILGL---SRSLVAERFDDIVRFSELSDFM--DQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEK 187
Cdd:cd03234   103 TYT-AILRLprkSSDAIRKKRVEDVLLRDLALTRigGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALN 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 188 CFDVFRRFKKEGRTIIFVSHDMGS-IQEFSDRVLILNHGRPrgIYS 232
Cdd:cd03234   182 LVSTLSQLARRNRIVILTIHQPRSdLFRLFDRILLLSSGEI--VYS 225
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 44-226 1.79e-11

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 63.40  E-value: 1.79e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELG-----VG--------FNAelTARE 110
Cdd:cd03251    17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLAslrrqIGlvsqdvflFND--TVAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVflSGAILGLSRslvaERFDDIVRFSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:cd03251    95 NI--AYGRPGATR----EEVEEAARAANAHEFIMELPEGYdtvigergvklSGGQRQRIAIARALLKDPPILILDEATSA 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03251   169 LDTESERLVQAALERLMK-NRTTFVIAHRLSTIEN-ADRIVVLEDGK 213
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 43-226 1.87e-11

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 62.93  E-value: 1.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGI--YRPTSGRVSVTGL----LSPfielgvgfnaELTARENVFLSg 116
Cdd:cd03217    14 EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEditdLPP----------EERARLGIFLA- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 117 ailglsrslvaerFDDIVRFSE--LSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRR 194
Cdd:cd03217    83 -------------FQYPPEIPGvkNADFLRYVNEGFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINK 149

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1671187127 195 FKKEGRTIIFVSHdMGSIQEF--SDRVLILNHGR 226
Cdd:cd03217   150 LREEGKSVLIITH-YQRLLDYikPDRVHVLYDGR 182
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 38-175 2.11e-11

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 63.33  E-value: 2.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----SVTGLlsPFIE---LGVGFNA----- 104
Cdd:cd03218    11 GKRK--VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKIlldgqDITKL--PMHKrarLGIGYLPqeasi 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 105 --ELTARENVFLSGAILGLSRSLVAERFDDIvrfseLSDFMDQKLKN-----YSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:cd03218    87 frKLTVEENILAVLEIRGLSKKEREEKLEEL-----LEEFHITHLRKskassLSGGERRRVEIARALATNPKFLLLDE 159
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
34-226 2.23e-11

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 65.37  E-value: 2.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRleALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-------LLSPFIELGVGF-NAE 105
Cdd:PRK13657  342 FSYDNSRQ--GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGtdirtvtRASLRRNIAVVFqDAG 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTAR---ENVflsgaILGLSRSLVAERFDDIVRfSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADIL 171
Cdd:PRK13657  420 LFNRsieDNI-----RVGRPDATDEEMRAAAER-AQAHDFIERKPDGYdtvvgergrqlSGGERQRLAIARALLKDPPIL 493

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 172 LVDEVLAVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:PRK13657  494 ILDEATSALDVETEAKVKAALDELMK-GRTTFIIAHRLSTVRN-ADRILVFDNGR 546
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 44-225 3.73e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 65.42  E-value: 3.73e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG--LLSPFIEL--GVGFNAE-------LTARENV 112
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGksILTNISDVhqNMGYCPQfdaiddlLTGREHL 2033

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  113 FLSGAIlglsRSLVAERFDDIVRFS----ELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:TIGR01257 2034 YLYARL----RGVPAEEIEKVANWSiqslGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRML 2109

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1671187127  189 FDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:TIGR01257 2110 WNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
38-209 4.25e-11

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 62.53  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPFIELGVGFNAEL----------- 106
Cdd:PRK11629   18 GSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNG--QPMSKLSSAAKAELrnqklgfiyqf 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 -------TARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:PRK11629   96 hhllpdfTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGN 175

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1671187127 180 GDASFQEKCFDVFRRF-KKEGRTIIFVSHDM 209
Cdd:PRK11629  176 LDARNADSIFQLLGELnRLQGTAFLVVTHDL 206
cbiO PRK13645
energy-coupling factor transporter ATPase;
42-233 4.82e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 63.10  E-value: 4.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPF------------IELGVGFN------ 103
Cdd:PRK13645   24 FKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPAnlkkikevkrlrKEIGLVFQfpeyql 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILGLSRSLVAERFDDIVRFSEL-SDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDA 182
Cdd:PRK13645  104 FQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDP 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 183 SFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRPRGIYSP 233
Cdd:PRK13645  184 KGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSP 235
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 60-231 6.13e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 64.04  E-value: 6.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  60 VIGPNGSGKSTLLKIMAGIYRPTSGRVSV-------------TGLLSPFIELgvgFNAELTAR---ENV-FLSGAILGLS 122
Cdd:COG1245   104 ILGPNGIGKSTALKILSGELKPNLGDYDEepswdevlkrfrgTELQDYFKKL---ANGEIKVAhkpQYVdLIPKVFKGTV 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 123 RSL---VAER--FDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVlavgdASFqekcFDVFRRFK- 196
Cdd:COG1245   181 RELlekVDERgkLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP-----SSY----LDIYQRLNv 251

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 197 --------KEGRTIIFVSHDMGSIQEFSDRVLILnHGRPrGIY 231
Cdd:COG1245   252 arlirelaEEGKYVLVVEHDLAILDYLADYVHIL-YGEP-GVY 292
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 38-224 6.67e-11

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 62.05  E-value: 6.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLL-----------SPFIELGVG-Fnae 105
Cdd:PRK09544   15 GQRRV--LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLrigyvpqklylDTTLPLTVNrF--- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVFLSGAILGLSRslvaerfddiVRFSELSDFMDQKLknySSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ 185
Cdd:PRK09544   90 LRLRPGTKKEDILPALKR----------VQAGHLIDAPMQKL---SGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQ 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1671187127 186 EKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNH 224
Cdd:PRK09544  157 VALYDLIDQLRRElDCAVLMVSHDLHLVMAKTDEVLCLNH 196
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 38-208 9.70e-11

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 61.33  E-value: 9.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELG--------VGFNAE--- 105
Cdd:PRK10584   19 GEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQpLHQMDEEAraklrakhVGFVFQsfm 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 ----LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:PRK10584   99 liptLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178

                         170       180
                  ....*....|....*....|....*...
gi 1671187127 182 ASFQEKCFD-VFRRFKKEGRTIIFVSHD 208
Cdd:PRK10584  179 RQTGDKIADlLFSLNREHGTTLILVTHD 206
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 54-222 9.98e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 59.69  E-value: 9.98e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   54 RGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllspfielgvgfnaeltarenvflsgailglsrsLVAERFDDI 133
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY------------------------------------IDGEDILEE 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  134 VRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ------EKCFDVFRRFKKEGRTIIFVSH 207
Cdd:smart00382  45 VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEalllllEELRLLLLLKSEKNLTVILTTN 124

                          170       180
                   ....*....|....*....|
gi 1671187127  208 DMGSIQE-----FSDRVLIL 222
Cdd:smart00382 125 DEKDLGPallrrRFDRRIVL 144
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 37-227 1.23e-10

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 62.29  E-value: 1.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  37 AGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG------------LLSPFIELgVGFN- 103
Cdd:PRK11308   23 KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGqdllkadpeaqkLLRQKIQI-VFQNp 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 -AELTARENVflsGAILG--------LSRSLVAERFDDIVRFSEL-SDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLV 173
Cdd:PRK11308  102 yGSLNPRKKV---GQILEepllintsLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVA 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 174 DEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRP 227
Cdd:PRK11308  179 DEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSVVEHIADEVMVMYLGRC 233
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 29-261 1.33e-10

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 61.23  E-value: 1.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFRPAGSRRlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGrvsvtgllspfiELGVGfNAELT- 107
Cdd:PRK11247   13 LLLNAVSKRYGER-TVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAG------------ELLAG-TAPLAe 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLsgaILGLSRSLVAERFDDIVRFSELSDFMDQKLK----------------NYSSGMLVRLAFAVAIQAHADIL 171
Cdd:PRK11247   79 AREDTRL---MFQDARLLPWKKVIDNVGLGLKGQWRDAALQalaavgladranewpaALSGGQKQRVALARALIHRPGLL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 172 LVDEVLAVGDASFQEKCFDVFRR-FKKEGRTIIFVSHDMGSIQEFSDRVLILNHG-----------RPRGIYSPAGAAVE 239
Cdd:PRK11247  156 LLDEPLGALDALTRIEMQDLIESlWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGkigldltvdlpRPRRRGSARLAELE 235

                         250       260
                  ....*....|....*....|..
gi 1671187127 240 YSRLneehaNRLLSDSKAAPTS 261
Cdd:PRK11247  236 AEVL-----QRVMSRGESEPTR 252
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
60-231 1.58e-10

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 62.90  E-value: 1.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  60 VIGPNGSGKSTLLKIMAGIYRPTSGRVSV-------------TGLLSPFIELgvgFNAELTARENV----FLSGAILGLS 122
Cdd:PRK13409  104 ILGPNGIGKTTAVKILSGELIPNLGDYEEepswdevlkrfrgTELQNYFKKL---YNGEIKVVHKPqyvdLIPKVFKGKV 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 123 RSL---VAER--FDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVlavgdASFqekcFDVFRRFK- 196
Cdd:PRK13409  181 RELlkkVDERgkLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP-----TSY----LDIRQRLNv 251

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1671187127 197 -------KEGRTIIFVSHDMGSIQEFSDRVLILnHGRPrGIY 231
Cdd:PRK13409  252 arlirelAEGKYVLVVEHDLAVLDYLADNVHIA-YGEP-GAY 291
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 45-226 1.71e-10

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 60.56  E-value: 1.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-LSPFIELGVGFNAELTARENVFLSGAIL-GLS 122
Cdd:cd03248    30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKpISQYEHKYLHSKVSLVGQEPVLFARSLQdNIA 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 123 RSLVAERFDDIVR----------FSELSDFMD----QKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:cd03248   110 YGLQSCSFECVKEaaqkahahsfISELASGYDtevgEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQV 189

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1671187127 189 FDVFRRFkKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03248   190 QQALYDW-PERRTVLVIAHRLSTVER-ADQILVLDGGR 225
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
44-175 1.96e-10

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 62.83  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPfIELG-------VGF-------NAELTAR 109
Cdd:NF033858  281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFG--QP-VDAGdiatrrrVGYmsqafslYGELTVR 357

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIV-RFsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:NF033858  358 QNLELHARLFHLPAAEIAARVAEMLeRF-DLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDE 423
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 43-226 2.12e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 60.63  E-value: 2.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYR-----PTSGRVSVTG--LLSPFI-------ELGVGFN----- 103
Cdd:PRK14267   18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElneeaRVEGEVRLFGrnIYSPDVdpievrrEVGMVFQypnpf 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILGLSRSlvAERFDDIVRFS--------ELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:PRK14267   98 PHLTIYDNVAIGVKLNGLVKS--KKELDERVEWAlkkaalwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 176 VLA----VGDASFQEKCFDVfrrfkKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK14267  176 PTAnidpVGTAKIEELLFEL-----KKEYTIVLVTHSPAQAARVSDYVAFLYLGK 225
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
43-324 2.29e-10

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 61.40  E-value: 2.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPfielgvgfnAE------------- 105
Cdd:PRK11650   18 QVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRvvneLEP---------ADrdiamvfqnyaly 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 --LTARENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDAS 183
Cdd:PRK11650   89 phMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAK 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 184 FQ-----EkcfdvFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIY-------------SPAGAAV 238
Cdd:PRK11650  169 LRvqmrlE-----IQRLHRRlKTTSLYVTHDQVEAMTLADRVVVMNGGVaeqigtPVEVYekpastfvasfigSPAMNLL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 239 EySRLNEEHANRLLSDSKAAPTSATSS-----------RP--------------RIVSVEMLdGNGQTTHAIQRGQSATI 293
Cdd:PRK11650  244 D-GRVSADGAAFELAGGIALPLGGGYRqyagrkltlgiRPehialssaeggvplTVDTVELL-GADNLAHGRWGGQPLVV 321

                         330       340       350
                  ....*....|....*....|....*....|....
gi 1671187127 294 RLkianPQREPVNAGVAIY---RDDGLHCFGTNT 324
Cdd:PRK11650  322 RL----PHQERPAAGSTLWlhlPANQLHLFDADT 351
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
7-225 2.38e-10

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 60.57  E-value: 2.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRvplerttslkqlaargFRPAGSRR--LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSG 84
Cdd:PRK15112    5 LEVRNLSKTFR----------------YRTGWFRRqtVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSG 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  85 RVSVTGllSPFIELGVGFNAE------------LTARENVflsGAIL--------GLSRSLVAERFDDIVR-FSELSDFM 143
Cdd:PRK15112   69 ELLIDD--HPLHFGDYSYRSQrirmifqdpstsLNPRQRI---SQILdfplrlntDLEPEQREKQIIETLRqVGLLPDHA 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 144 DQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFK-KEGRTIIFVSHDMGSIQEFSDRVLIL 222
Cdd:PRK15112  144 SYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQeKQGISYIYVTQHLGMMKHISDQVLVM 223


                  ...
gi 1671187127 223 NHG 225
Cdd:PRK15112  224 HQG 226
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 2-207 2.64e-10

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 59.97  E-value: 2.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   2 QTDVAISIEHLTKVFRVPLERTTSLKQLAaRGFRpAGSRRLE--ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIY 79
Cdd:COG2401     3 RYNPFFVLMRVTKVYSSVLDLSERVAIVL-EAFG-VELRVVEryVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  80 --RPTSGRVSVtgllsPFIElgvgFNAELTARENVFLSGAILG----LSRSLVAERFDDIVRFSELSDfmDQKLknyssg 153
Cdd:COG2401    81 kgTPVAGCVDV-----PDNQ----FGREASLIDAIGRKGDFKDavelLNAVGLSDAVLWLRRFKELST--GQKF------ 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 154 mlvRLAFAVAIQAHADILLVDEVLAVGDASF-QEKCFDVFRRFKKEGRTIIFVSH 207
Cdd:COG2401   144 ---RFRLALLLAERPKLLVIDEFCSHLDRQTaKRVARNLQKLARRAGITLVVATH 195
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 42-226 2.75e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 61.76  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPT---SGRVSVTGllSPFIELGV---------------GFN 103
Cdd:TIGR02633  14 VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVY-PHgtwDGEIYWSG--SPLKASNIrdteragiviihqelTLV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILG----LSRSLVAERFDDIVRFSELSDFMDQK-LKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:TIGR02633  91 PELSVAENIFLGNEITLpggrMAYNAMYLRAKNLLRELQLDADNVTRpVGDYGGGQQQLVEIAKALNKQARLLILDEPSS 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 179 VGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:TIGR02633 171 SLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 44-226 3.75e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 61.48  E-value: 3.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPT---SGRVSVTG--LLSPFI-------------ELGVgfNAE 105
Cdd:PRK13549   20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHgtyEGEIIFEGeeLQASNIrdteragiaiihqELAL--VKE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVFLSGAILGLSR---SLVAERFDDIVRFSELSDFMDQKLKNYSSG--MLVRLAFAVAIQAHadILLVDEVLAVG 180
Cdd:PRK13549   97 LSVLENIFLGNEITPGGImdyDAMYLRAQKLLAQLKLDINPATPVGNLGLGqqQLVEIAKALNKQAR--LLILDEPTASL 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 181 DASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK13549  175 TESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 43-148 3.80e-10

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 61.49  E-value: 3.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVsvtgLLSPFIELGV-----GFNAELTARENVFLSga 117
Cdd:TIGR03719  19 EILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEA----RPQPGIKVGYlpqepQLDPTKTVRENVEEG-- 92

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1671187127 118 iLGLSRSLVAeRFDDI-VRFSELSDFMDQKLK 148
Cdd:TIGR03719  93 -VAEIKDALD-RFNEIsAKYAEPDADFDKLAA 122
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 42-226 4.02e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 61.36  E-value: 4.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV----------------TGLLSPFI--------- 96
Cdd:TIGR03269 297 VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdewvdmtkpgpdgRGRAKRYIgilhqeydl 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  97 ------------ELGVGFNAELTARENVFlsgailglsrSLVAERFDDIVRFSELSDFMDQklknYSSGMLVRLAFAVAI 164
Cdd:TIGR03269 377 yphrtvldnlteAIGLELPDELARMKAVI----------TLKMVGFDEEKAEEILDKYPDE----LSEGERHRVALAQVL 442

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127 165 QAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:TIGR03269 443 IKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGK 505
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 60-144 5.06e-10

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 61.29  E-value: 5.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  60 VIGPNGSGKSTLLKIMAGIYRPTSGRVsvtgLLSPFIElgVGF-------NAELTARENVflsgaILGLSRSLVA-ERFD 131
Cdd:PRK11819   38 VLGLNGAGKSTLLRIMAGVDKEFEGEA----RPAPGIK--VGYlpqepqlDPEKTVRENV-----EEGVAEVKAAlDRFN 106

                          90
                  ....*....|....
gi 1671187127 132 DI-VRFSELSDFMD 144
Cdd:PRK11819  107 EIyAAYAEPDADFD 120
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 43-226 5.68e-10

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 59.17  E-value: 5.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-------LLSPFIELGVG------FNAelTAR 109
Cdd:cd03253    15 PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGqdirevtLDSLRRAIGVVpqdtvlFND--TIG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVflsgAILGLSRS--------LVAERFDDIVRFSELSDFM--DQKLKnYSSGMLVRLAFAVAIQAHADILLVDEVLAV 179
Cdd:cd03253    93 YNI----RYGRPDATdeevieaaKAAQIHDKIMRFPDGYDTIvgERGLK-LSGGEKQRVAIARAILKNPPILLLDEATSA 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03253   168 LDTHTEREIQAALRDVSK-GRTTIVIAHRLSTIVN-ADKIIVLKDGR 212
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
46-234 7.99e-10

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 59.23  E-value: 7.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  46 QDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG-----LLSPFIELGVGFNAE-------LTARENV- 112
Cdd:PRK10253   24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGehiqhYASKEVARRIGLLAQnattpgdITVQELVa 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 ---FLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:PRK10253  104 rgrYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 190 DVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR------PRGIYSPA 234
Cdd:PRK10253  184 ELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKivaqgaPKEIVTAE 235
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 4-226 8.85e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 59.48  E-value: 8.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFRvplERTtslkqlaargfrpagSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:PRK13631   19 DIILRVKNLYCVFD---EKQ---------------ENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVTGLLS-PFIELGVGFNAELTAR---------------------------ENVFLSGAI-LGLSRSLVAERFDD-I 133
Cdd:PRK13631   81 GTIQVGDIYIgDKKNNHELITNPYSKKiknfkelrrrvsmvfqfpeyqlfkdtiEKDIMFGPVaLGVKKSEAKKLAKFyL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 134 VRFSELSDFMDQKLKNYSSGMLVRLAFA--VAIQAhaDILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGS 211
Cdd:PRK13631  161 NKMGLDDSYLERSPFGLSGGQKRRVAIAgiLAIQP--EILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEH 238

                         250
                  ....*....|....*
gi 1671187127 212 IQEFSDRVLILNHGR 226
Cdd:PRK13631  239 VLEVADEVIVMDKGK 253
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 39-226 9.58e-10

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 59.33  E-value: 9.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  39 SRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLSPFIELGVGFN---AE 105
Cdd:PRK15079   31 PKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGkdllgmkddeWRAVRSDIQMIFQdplAS 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVflsGAILG---------LSRSLVAERFDDIV-RFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:PRK15079  111 LNPRMTI---GEIIAeplrtyhpkLSRQEVKDRVKAMMlKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDE 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 176 VLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK15079  188 PVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYLGH 239
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 45-86 1.08e-09

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 58.54  E-value: 1.08e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGI--YRPTSGRV 86
Cdd:COG0396    16 LKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSI 59
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 44-225 1.14e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 60.02  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFI------ELGVG-----FN--AELTARE 110
Cdd:PRK10762   19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNgpkssqEAGIGiihqeLNliPQLTIAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 NVFLS-------GAILGlsRSLVAERfDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVL-AVGDA 182
Cdd:PRK10762   99 NIFLGrefvnrfGRIDW--KKMYAEA-DKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTdALTDT 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 183 SfQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK10762  176 E-TESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDG 217
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 45-225 1.23e-09

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 58.71  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSpfielgvgFNAEL------TARENVflsgaI 118
Cdd:cd03291    53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRIS--------FSSQFswimpgTIKENI-----I 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 119 LGLS------RSLV--AERFDDIVRFSELSD-FMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:cd03291   120 FGVSydeyryKSVVkaCQLEEDITKFPEKDNtVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEIF 199

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHG 225
Cdd:cd03291   200 ESCVCKLMANKTRILVTSKMEHLKK-ADKILILHEG 234
PTZ00243 PTZ00243
ABC transporter; Provisional
 45-226 1.57e-09

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 60.18  E-value: 1.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVsvtgllspFIELGVGFNAELTARENVFLSGAILGLSRS 124
Cdd:PTZ00243   676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV--------WAERSIAYVPQQAWIMNATVRGNILFFDEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  125 lVAERFDDIVRFSELSDFMDQ-----------KLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF-DVF 192
Cdd:PTZ00243   748 -DAARLADAVRVSQLEADLAQlgggleteigeKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVVeECF 826

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1671187127  193 RRfKKEGRTIIFVSHDMgSIQEFSDRVLILNHGR 226
Cdd:PTZ00243   827 LG-ALAGKTRVLATHQV-HVVPRADYVVALGDGR 858
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 45-225 1.62e-09

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 58.13  E-value: 1.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPF-------------IELGVGFNA-----EL 106
Cdd:PRK14246   26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFgkdifqidaiklrKEVGMVFQQpnpfpHL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVFLSGAILGLS-----RSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGD 181
Cdd:PRK14246  106 SIYDNIAYPLKSHGIKekreiKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMID 185

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1671187127 182 ASFQEKCFDVFRRFKKEgRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK14246  186 IVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNG 228
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 51-234 2.53e-09

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 56.04  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  51 EITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVtgllspfielgvgfnaeltarenvflsgailglsrslvaerf 130
Cdd:cd03222    21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEW------------------------------------------ 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 131 dDIVRFSelsdFMDQKLKnYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEG-RTIIFVSHDM 209
Cdd:cd03222    59 -DGITPV----YKPQYID-LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGkKTALVVEHDL 132

                         170       180
                  ....*....|....*....|....*
gi 1671187127 210 GSIQEFSDRVLILnHGRPrGIYSPA 234
Cdd:cd03222   133 AVLDYLSDRIHVF-EGEP-GVYGIA 155
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 34-224 2.53e-09

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 56.01  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRLEalqDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVsvtgllspfielgvgfnaELTARENV- 112
Cdd:cd03223     9 ATPDGRVLLK---DLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRI------------------GMPEGEDLl 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 FLSGA---ILGLSRSLVAERFDDIVrfselsdfmdqklknySSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKcf 189
Cdd:cd03223    68 FLPQRpylPLGTLREQLIYPWDDVL----------------SGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDR-- 129

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1671187127 190 dVFRRFKKEGRTIIFVSHDMgSIQEFSDRVLILNH 224
Cdd:cd03223   130 -LYQLLKELGITVISVGHRP-SLWKFHDRVLDLDG 162
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
42-226 2.89e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 58.21  E-value: 2.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLlKIMAGIYRPTSGRV------------SVTGLLSPFIELGVGFNAELTAR 109
Cdd:NF000106   26 VKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRpwrf*twcanrrALRRTIG*HRPVR*GRRESFSGR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:NF000106  105 ENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVW 184

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1671187127 190 DVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:NF000106  185 DEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGR 221
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
38-111 3.39e-09

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 56.35  E-value: 3.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  38 GSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG---------LLSPFIELG--VGFNAEL 106
Cdd:PRK13538   12 DERIL--FSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGepirrqrdeYHQDLLYLGhqPGIKTEL 89


                  ....*
gi 1671187127 107 TAREN 111
Cdd:PRK13538   90 TALEN 94
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 29-226 3.45e-09

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 57.24  E-value: 3.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  29 LAARGFRPAGSRRLeALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVT---GLLSPFIELGV----- 100
Cdd:PRK11701    7 LSVRGLTKLYGPRK-GCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRmrdGQLRDLYALSEaerrr 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 ------GF---NAELTARENVfLSGAILGLSRSLVAERFDDIVRfSELSDFM----------DQKLKNYSSGMLVRLAFA 161
Cdd:PRK11701   86 llrtewGFvhqHPRDGLRMQV-SAGGNIGERLMAVGARHYGDIR-ATAGDWLerveidaariDDLPTTFSGGMQQRLQIA 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1671187127 162 VAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK11701  164 RNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGR 229
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 42-226 3.45e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 58.59  E-value: 3.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPF------IELGVGF-NAELT-ARENVF 113
Cdd:PRK10982   11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFksskeaLENGISMvHQELNlVLQRSV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 LSGAILG---LSRSLVAER--FDDIVR-FSELSDFMDQKLK--NYSSGMLVRLAFAVAIQAHADILLVDEvlavGDASFQ 185
Cdd:PRK10982   91 MDNMWLGrypTKGMFVDQDkmYRDTKAiFDELDIDIDPRAKvaTLSVSQMQMIEIAKAFSYNAKIVIMDE----PTSSLT 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 186 EK----CFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10982  167 EKevnhLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQ 211
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 44-226 3.69e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 58.30  E-value: 3.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------------LLSPFIELgvgFNAELt 107
Cdd:PRK11160  355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGqpiadyseaalrqaisVVSQRVHL---FSATL- 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 aRENVFLSGAilglsrSLVAERFDDIVRFSELSDFM--DQKLKNY--------SSGMLVRLAFAVAIQAHADILLVDEVL 177
Cdd:PRK11160  431 -RDNLLLAAP------NASDEALIEVLQQVGLEKLLedDKGLNAWlgeggrqlSGGEQRRLGIARALLHDAPLLLLDEPT 503

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1671187127 178 AVGDASFQEKCFDVFRRFKKeGRTIIFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:PRK11160  504 EGLDAETERQILELLAEHAQ-NKTVLMITHRLTGLEQF-DRICVMDNGQ 550
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 43-225 3.81e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 58.14  E-value: 3.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPFIELGVGFN---------AELTAR 109
Cdd:PRK15439   25 EVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNpcarLTPAKAHQLGIYlvpqepllfPNLSVK 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVflsgaILGLSRSLVAER------------FDDIVRFSELsDFMDQKLKNYSSGmLVRlafavaiqaHADILLVDEVL 177
Cdd:PRK15439  105 ENI-----LFGLPKRQASMQkmkqllaalgcqLDLDSSAGSL-EVADRQIVEILRG-LMR---------DSRILILDEPT 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 178 AVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK15439  169 ASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
GguA NF040905
sugar ABC transporter ATP-binding protein;
44-226 6.88e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 57.49  E-value: 6.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPT---SGRVSVTGLLSPF--I----ELGV-------GFNAELT 107
Cdd:NF040905   16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY-PHgsyEGEILFDGEVCRFkdIrdseALGIviihqelALIPYLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFL------SGAIlglSRSLVAERFDDIVRFSELSDFMDQKLKNYSSGM--LVRLAFAVAiqAHADILLVDEVLAV 179
Cdd:NF040905   95 IAENIFLgnerakRGVI---DWNETNRRARELLAKVGLDESPDTLVTDIGVGKqqLVEIAKALS--KDVKLLILDEPTAA 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127 180 GDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:NF040905  170 LNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGR 216
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
 43-115 6.91e-09

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 56.11  E-value: 6.91e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAG--IYRPTSGRVSVTGllSPFIELGVgfnaELTARENVFLS 115
Cdd:TIGR01978  14 EILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGhpSYEVTSGTILFKG--QDLLELEP----DERARAGLFLA 82
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
43-258 8.88e-09

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 56.17  E-value: 8.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIE---------------LGVGFNA--- 104
Cdd:PRK09984   18 QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQregrlardirksranTGYIFQQfnl 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 105 --ELTARENVfLSGAiLG-----------LSRSLVAERFDDIVRFSeLSDFMDQKLKNYSSGMLVRLAFAVAIQAHADIL 171
Cdd:PRK09984   98 vnRLSVLENV-LIGA-LGstpfwrtcfswFTREQKQRALQALTRVG-MVHFAHQRVSTLSGGQQQRVAIARALMQQAKVI 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 172 LVDEVLAVGDASFQEKCFDVFRRFKK-EGRTIIFVSHDMGSIQEFSDRVLILNHGRPrgIYSPAGAAVEYSRLNEEH--A 248
Cdd:PRK09984  175 LADEPIASLDPESARIVMDTLRDINQnDGITVVVTLHQVDYALRYCERIVALRQGHV--FYDGSSQQFDNERFDHLYrsI 252

                         250
                  ....*....|
gi 1671187127 249 NRLLSDSKAA 258
Cdd:PRK09984  253 NRVEENAKAA 262
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
44-154 1.12e-08

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.06  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----------LLSPFIEL---GVGFN--AELTA 108
Cdd:NF033858   16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGgdmadarhrrAVCPRIAYmpqGLGKNlyPTLSV 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1671187127 109 RENVFLSGAILGLSRSLVAERFDDIVRFSELSDFMD---QKLknySSGM 154
Cdd:NF033858   96 FENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADrpaGKL---SGGM 141
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 45-226 1.12e-08

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 57.04  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPFIELGVGF---NAELTARENVFLSGAI--- 118
Cdd:TIGR00958 497 LKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG--VPLVQYDHHYlhrQVALVGQEPVLFSGSVren 574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 119 --LGLSRSLVAErFDDIVRFSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQ 185
Cdd:TIGR00958 575 iaYGLTDTPDEE-IMAAAKAANAHDFIMEFPNGYdtevgekgsqlSGGQKQRIAIARALVRKPRVLILDEATSALDAECE 653

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1671187127 186 EKcfdVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:TIGR00958 654 QL---LQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGS 690
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 43-233 1.34e-08

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 54.73  E-value: 1.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGvGFNAELT--ARENVFLSGAIlg 120
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLE-DLRSSLTiiPQDPTLFSGTI-- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 121 lsRSLVaERFDdivRFSELSDFMDQKLK----NYSSGMLVRLAFAVAIQAHADILLVDEVLA----VGDASFQEKCFDVF 192
Cdd:cd03369    99 --RSNL-DPFD---EYSDEEIYGALRVSegglNLSQGQRQLLCLARALLKRPRVLVLDEATAsidyATDALIQKTIREEF 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1671187127 193 rrfkkEGRTIIFVSHDMGSIQEFsDRVLILNHGRPRGIYSP 233
Cdd:cd03369   173 -----TNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
21-226 1.87e-08

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 55.18  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  21 ERTTSLKQLAargFRPAGsRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllspfiELGV 100
Cdd:PRK10575    9 DTTFALRNVS---FRVPG-RTL--LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDA------QPLE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 GFNAELTARENVFLSG---AILGLS-RSLVA------------------ERFDDIVRFSELSDFMDQKLKNYSSGMLVRL 158
Cdd:PRK10575   77 SWSSKAFARKVAYLPQqlpAAEGMTvRELVAigrypwhgalgrfgaadrEKVEEAISLVGLKPLAHRLVDSLSGGERQRA 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 159 AFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10575  157 WIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGE 225
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 45-225 2.42e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 56.46  E-value: 2.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS-----PFIELGvgfnaelTARENVflsgaIL 119
Cdd:TIGR01271  442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISfspqtSWIMPG-------TIKDNI-----IF 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  120 GLS------RSLV--AERFDDIVRFSELSD--FMDQKLkNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCF 189
Cdd:TIGR01271  510 GLSydeyryTSVIkaCQLEEDIALFPEKDKtvLGEGGI-TLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEKEIF 588

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1671187127  190 DVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHG 225
Cdd:TIGR01271  589 ESCLCKLMSNKTRILVTSKLEHLKK-ADKILLLHEG 623
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 49-208 4.04e-08

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 52.36  E-value: 4.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  49 SIEITRGEFFSVIGPNGSGKSTLLKImagiyrptsgrvsvtgllspfIELGVGFNAELTARENVFLSGAILGLSRslvAE 128
Cdd:cd03227    15 DVTFGEGSLTIITGPNGSGKSTILDA---------------------IGLALGGAQSATRRRSGVKAGCIVAAVS---AE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 129 RfddIVRFSELsdfmdqklknySSGM--LVRLAFAVAIQAHAD--ILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIF 204
Cdd:cd03227    71 L---IFTRLQL-----------SGGEkeLSALALILALASLKPrpLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIV 136


                  ....
gi 1671187127 205 VSHD 208
Cdd:cd03227   137 ITHL 140
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 45-88 6.21e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 54.57  E-value: 6.21e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV 88
Cdd:PRK11147  335 VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC 378
hmuV PRK13547
heme ABC transporter ATP-binding protein;
45-240 8.68e-08

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 52.91  E-value: 8.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYrPTSGR---VSVTGLLSPFIELGVGFNAELTARENVFLSGAilgl 121
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDL-TGGGAprgARVTGDVTLNGEPLAAIDAPRLARLRAVLPQA---- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 122 SRSLVAERFDDIV---------RFSELS----DFMDQKLK-------------NYSSGMLVRLAFA-VAIQAHAD----- 169
Cdd:PRK13547   92 AQPAFAFSAREIVllgrypharRAGALThrdgEIAWQALAlagatalvgrdvtTLSGGELARVQFArVLAQLWPPhdaaq 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 170 ---ILLVDEVLAVGDASFQEKCFDVFRRFKKEGRT-IIFVSHDMGSIQEFSDRVL------ILNHGRPRGIYSPAGAAVE 239
Cdd:PRK13547  172 pprYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgVLAIVHDPNLAARHADRIAmladgaIVAHGAPADVLTPAHIARC 251


                  .
gi 1671187127 240 Y 240
Cdd:PRK13547  252 Y 252
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 43-226 9.22e-08

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 52.54  E-value: 9.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELG--------VG-----FNAelTAR 109
Cdd:cd03249    17 PILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRwlrsqiglVSqepvlFDG--TIA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 110 ENVflsgaILGLSRSLVAERfDDIVRFSELSDFMDQKLKNY-----------SSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:cd03249    95 ENI-----RYGKPDATDEEV-EEAAKKANIHDFIMSLPDGYdtlvgergsqlSGGQKQRIAIARALLRNPKILLLDEATS 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1671187127 179 VGDAS----FQEKcFDVFRRfkkeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03249   169 ALDAEseklVQEA-LDRAMK----GRTTIVIAHRLSTIRN-ADLIAVLQNGQ 214
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 36-225 1.03e-07

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 51.86  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  36 PAGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGiyRPTSGRVSVTGLLS-----PFIELGVGF-------N 103
Cdd:cd03232    16 KGGKRQL--LNNISGYVKPGTLTALMGESGAGKTTLLDVLAG--RKTAGVITGEILINgrpldKNFQRSTGYveqqdvhS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILGLSrslVAERfddivrfselsdfmdqklknyssgmlVRLAFAVAIQAHADILLVDEVLAVGDAS 183
Cdd:cd03232    92 PNLTVREALRFSALLRGLS---VEQR--------------------------KRLTIGVELAAKPSILFLDEPTSGLDSQ 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1671187127 184 FQEKCFDVFRRFKKEGRTIIFVSHD-MGSIQEFSDRVLILNHG 225
Cdd:cd03232   143 AAYNIVRFLKKLADSGQAILCTIHQpSASIFEKFDRLLLLKRG 185
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-175 1.17e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 53.79  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFrvplerttslkqlaargfrpaGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:TIGR03719 320 DKVIEAENLTKAF---------------------GDKLL--IDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDS 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  84 GRVSVtgllSPFIELG-VG-FNAELTARENVF--LSGA--ILGL------SRSLVAeRFddivrfselsDFM--DQ--KL 147
Cdd:TIGR03719 377 GTIEI----GETVKLAyVDqSRDALDPNKTVWeeISGGldIIKLgkreipSRAYVG-RF----------NFKgsDQqkKV 441

                         170       180
                  ....*....|....*....|....*...
gi 1671187127 148 KNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:TIGR03719 442 GQLSGGERNRVHLAKTLKSGGNVLLLDE 469
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 28-234 1.17e-07

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 53.66  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  28 QLAARGF---RPAGSRRLEalqDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLS-------PFIE 97
Cdd:COG4178   362 ALALEDLtlrTPDGRPLLE---DLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPAGARvlflpqrPYLP 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  98 LGvgfnaelTARENvflsgailgLSRSLVAERFDD--------IVRFSELSDFMDQKL---KNYSSGMLVRLAFAVAIQA 166
Cdd:COG4178   439 LG-------TLREA---------LLYPATAEAFSDaelrealeAVGLGHLAERLDEEAdwdQVLSLGEQQRLAFARLLLH 502

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1671187127 167 HADILLVDEVLAVGDASFQEKCFDVFRRfKKEGRTIIFVSHDmGSIQEFSDRVLILnHGRPRGIYSPA 234
Cdd:COG4178   503 KPDWLFLDEATSALDEENEAALYQLLRE-ELPGTTVISVGHR-STLAAFHDRVLEL-TGDGSWQLLPA 567
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 8-226 1.39e-07

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 53.51  E-value: 1.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   8 SIEHLTKVFRVPLErtTSLKQLAARGFRPAGSRR--LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGiYRPT--- 82
Cdd:TIGR00955   4 SWRNSDVFGRVAQD--GSWKQLVSRLRGCFCRERprKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAF-RSPKgvk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  83 -SGRVSVTG---------LLSPFI---ELGVGfnaELTARENVFLSgAILGLSRSLVA----ERFDDIVRFSELSDFMDQ 145
Cdd:TIGR00955  81 gSGSVLLNGmpidakemrAISAYVqqdDLFIP---TLTVREHLMFQ-AHLRMPRRVTKkekrERVDEVLQALGLRKCANT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 146 K------LKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGS-IQEFSDR 218
Cdd:TIGR00955 157 RigvpgrVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSeLFELFDK 236


                  ....*...
gi 1671187127 219 VLILNHGR 226
Cdd:TIGR00955 237 IILMAEGR 244
PLN03232 PLN03232
ABC transporter C family member; Provisional
 45-225 1.47e-07

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 53.83  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPT-SGRVSVTGLLSPFIELGVGFNAelTARENVfLSGAILGLSR 123
Cdd:PLN03232   633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAeTSSVVIRGSVAYVPQVSWIFNA--TVRENI-LFGSDFESER 709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  124 -----SLVAERFD-DIVRFSELSDFMDQKLkNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKK 197
Cdd:PLN03232   710 ywraiDVTALQHDlDLLPGRDLTEIGERGV-NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDSCMKDEL 788

                          170       180
                   ....*....|....*....|....*...
gi 1671187127  198 EGRTIIFVSHDMGSIQEFsDRVLILNHG 225
Cdd:PLN03232   789 KGKTRVLVTNQLHFLPLM-DRIILVSEG 815
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-226 1.55e-07

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 53.18  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  18 VPLERTTSlkQLAARGFRPAGSRRlEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIE 97
Cdd:PRK10789  307 VPEGRGEL--DVNIRQFTYPQTDH-PALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQ 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  98 LGvgfnaELTARENV-----FL-SGAILG---LSR-----------SLVAERFDDIVRFSELSDF-MDQKLKNYSSGMLV 156
Cdd:PRK10789  384 LD-----SWRSRLAVvsqtpFLfSDTVANniaLGRpdatqqeiehvARLASVHDDILRLPQGYDTeVGERGVMLSGGQKQ 458

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 157 RLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFkKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:PRK10789  459 RISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQW-GEGRTVIISAHRLSALTE-ASEILVMQHGH 526
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
49-226 3.18e-07

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 50.74  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  49 SIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSP--------FIElgvgfN---AELTARENVf 113
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGqdhtTTPPsrrpvsmlFQE-----NnlfSHLTVAQNI- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 114 lsgaILGLSRSL---VAER--FDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKC 188
Cdd:PRK10771   93 ----GLGLNPGLklnAAQRekLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEM 168

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1671187127 189 FDVFRRFKKEGR-TIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10771  169 LTLVSQVCQERQlTLLMVSHSLEDAARIAPRSLVVADGR 207
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 43-115 7.58e-07

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 50.03  E-value: 7.58e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAG--IYRPTSGRVSVTGllSPFIELgvgfNAELTARENVFLS 115
Cdd:CHL00131   21 EILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKG--ESILDL----EPEERAHLGIFLA 89
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 45-226 1.23e-06

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 49.12  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG---LLSPFIEL---GVGF---NAELTARENVFLS 115
Cdd:PRK10895   19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDediSLLPLHARarrGIGYlpqEASIFRRLSVYDN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 116 -GAILGLSRSLVAE----RFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFD 190
Cdd:PRK10895   99 lMAVLQIRDDLSAEqredRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKR 178

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1671187127 191 VFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10895  179 IIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGH 214
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 45-217 1.63e-06

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 49.26  E-value: 1.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIyRPTSGRVSVTGLLSPF----IELGVGFNA---------------E 105
Cdd:PRK14258   23 LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRM-NELESEVRVEGRVEFFnqniYERRVNLNRlrrqvsmvhpkpnlfP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 LTARENVFLSGAILGLSRSLvaeRFDDIV----RFSELSDFMDQKLK----NYSSGMLVRLAFAVAIQAHADILLVDEVL 177
Cdd:PRK14258  102 MSVYDNVAYGVKIVGWRPKL---EIDDIVesalKDADLWDEIKHKIHksalDLSGGQQQRLCIARALAVKPKVLLMDEPC 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1671187127 178 AVGD--ASFQEKCFDVFRRFKKEgRTIIFVSHDMGSIQEFSD 217
Cdd:PRK14258  179 FGLDpiASMKVESLIQSLRLRSE-LTMVIVSHNLHQVSRLSD 219
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
47-222 1.67e-06

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 48.99  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  47 DVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSP-----------------------FIELGVGFN 103
Cdd:PRK11831   25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPamsrsrlytvrkrmsmlfqsgalFTDMNVFDN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 104 AELTARENVFLSGAILglsRSLVAERFdDIVRFSELSDFMDQKLknySSGMLVRLAFAVAIQAHADILLVDEVLaVGDAS 183
Cdd:PRK11831  105 VAYPLREHTQLPAPLL---HSTVMMKL-EAVGLRGAAKLMPSEL---SGGMARRAALARAIALEPDLIMFDEPF-VGQDP 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1671187127 184 FQekcFDVFRRFKKE-----GRTIIFVSHDMGSIQEFSDRVLIL 222
Cdd:PRK11831  177 IT---MGVLVKLISElnsalGVTCVVVSHDVPEVLSIADHAYIV 217
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
52-178 1.83e-06

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 48.31  E-value: 1.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  52 ITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV------TGLLSPFIE-LG--VGFNAELTARENVFLSGAILGLS 122
Cdd:PRK13543   34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIdgktatRGDRSRFMAyLGhlPGLKADLSTLENLHFLCGLHGRR 113

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1671187127 123 RSLVAERFDDIVrfsELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:PRK13543  114 AKQMPGSALAIV---GLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYA 166
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 42-86 2.04e-06

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 49.80  E-value: 2.04e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127  42 LEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGI--YRPTSGRV 86
Cdd:TIGR03269  13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRI 59
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 45-90 2.27e-06

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 49.82  E-value: 2.27e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG 90
Cdd:COG5265   374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDG 419
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 4-88 3.37e-06

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 48.96  E-value: 3.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   4 DVAISIEHLTKVFrvplerttslkqlaargfrpaGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTS 83
Cdd:PRK11819  322 DKVIEAENLSKSF---------------------GDRLL--IDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDS 378


                  ....*
gi 1671187127  84 GRVSV 88
Cdd:PRK11819  379 GTIKI 383
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 43-238 5.32e-06

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 48.51  E-value: 5.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL----LSPF--IELGV----------GFNAEL 106
Cdd:PRK15439  277 EGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKeinaLSTAqrLARGLvylpedrqssGLYLDA 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 107 TARENVF-LSGAILGL-----SRSLVAERFDDI--VRFSELsdfmDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:PRK15439  357 PLAWNVCaLTHNRRGFwikpaRENAVLERYRRAlnIKFNHA----EQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTR 432

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 179 VGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRGiySPAGAAV 238
Cdd:PRK15439  433 GVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISG--ALTGAAI 490
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 44-225 6.21e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 46.16  E-value: 6.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKimAGIYrpTSGRVSVTGLLSPFIELGVGFNAELTARENVFLSGAILGlsr 123
Cdd:cd03238    10 NLQNLDVSIPLNVLVVVTGVSGSGKSTLVN--EGLY--ASGKARLISFLPKFSRNKLIFIDQLQFLIDVGLGYLTLG--- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 124 slvaerfddivrfselsdfmdQKLKNYSSGMLVRLAFAVAIQAHAD--ILLVDEVLAVGDASFQEKCFDVFRRFKKEGRT 201
Cdd:cd03238    83 ---------------------QKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIKGLIDLGNT 141

                         170       180
                  ....*....|....*....|....
gi 1671187127 202 IIFVSHDMGSIQEfSDRVLILNHG 225
Cdd:cd03238   142 VILIEHNLDVLSS-ADWIIDFGPG 164
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 43-75 7.44e-06

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 46.95  E-value: 7.44e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIM 75
Cdd:COG1117    25 QALKDINLDIPENKVTALIGPSGCGKSTLLRCL 57
PLN03211 PLN03211
ABC transporter G-25; Provisional
 7-226 7.93e-06

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 47.95  E-value: 7.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPLERTTSLKQLAAR--GFRPAGSRRLEALQDVSI------EITRGEFFSVIGPNGSGKSTLLKIMAGI 78
Cdd:PLN03211   38 ITLKFMDVCYRVKFENMKNKGSNIKRilGHKPKISDETRQIQERTIlngvtgMASPGEILAVLGPSGSGKSTLLNALAGR 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  79 YRPTS--GRVSVT-GLLSPFIELGVGFNAE-------LTAREN-VFLSgaILGLSRSLVAerfDDIVRFSE--LSDFMDQ 145
Cdd:PLN03211  118 IQGNNftGTILANnRKPTKQILKRTGFVTQddilyphLTVRETlVFCS--LLRLPKSLTK---QEKILVAEsvISELGLT 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 146 KLKN----------YSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGS-IQE 214
Cdd:PLN03211  193 KCENtiignsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSrVYQ 272

                         250
                  ....*....|..
gi 1671187127 215 FSDRVLILNHGR 226
Cdd:PLN03211  273 MFDSVLVLSEGR 284
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 43-218 9.18e-06

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 46.69  E-value: 9.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIM--AGIYRPTsgrVSVTG--------LLSPFI-------ELGVGFNA- 104
Cdd:PRK14239   19 KALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPE---VTITGsivynghnIYSPRTdtvdlrkEIGMVFQQp 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 105 ---ELTARENVFLSGAILGLSRSlvaERFDDIVRFS--------ELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLV 173
Cdd:PRK14239   96 npfPMSIYENVVYGLRLKGIKDK---QVLDEAVEKSlkgasiwdEVKDRLHDSALGLSGGQQQRVCIARVLATSPKIILL 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1671187127 174 DEVLAVGDASFQEKCFDVFRRFKKEgRTIIFVSHDMGSIQEFSDR 218
Cdd:PRK14239  173 DEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDR 216
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
60-226 1.25e-05

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 46.79  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  60 VIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGVGFNAELTARENVF----------LSGAIL-GLSRSLVAE 128
Cdd:PRK11144   29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPPEKRRIGYVFqdarlfphykVRGNLRyGMAKSMVAQ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 129 rFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKEGRT-IIFVSH 207
Cdd:PRK11144  109 -FDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIpILYVSH 187

                         170
                  ....*....|....*....
gi 1671187127 208 DMGSIQEFSDRVLILNHGR 226
Cdd:PRK11144  188 SLDEILRLADRVVVLEQGK 206
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 48-89 1.69e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 46.81  E-value: 1.69e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1671187127  48 VSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVT 89
Cdd:PRK15064   20 ISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLD 61
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 32-226 2.37e-05

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 46.22  E-value: 2.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  32 RGFRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTL-LKIMAGIyrPTSGRVSVTGllspfIELgvgfnAELTARE 110
Cdd:COG4172   289 RGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLI--PSEGEIRFDG-----QDL-----DGLSRRA 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 111 N---------VF------LS-----GAIL---------GLSRSLVAERFDDIVRFSELS-DFMDQklknY----SSGMLV 156
Cdd:COG4172   357 LrplrrrmqvVFqdpfgsLSprmtvGQIIaeglrvhgpGLSAAERRARVAEALEEVGLDpAARHR----YphefSGGQRQ 432

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 157 RLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRF-KKEGRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4172   433 RIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLqREHGLAYLFISHDLAVVRALAHRVMVMKDGK 503
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
45-226 3.44e-05

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 45.86  E-value: 3.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGllSPFIELgvgfnAELTARENV------------ 112
Cdd:PRK10790  357 LQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDG--RPLSSL-----SHSVLRQGVamvqqdpvvlad 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 113 -FLSGAILG-------LSRSLVAERFDDIVRfsELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVG 180
Cdd:PRK10790  430 tFLANVTLGrdiseeqVWQALETVQLAELAR--SLPDGLYTPLgeqgNNLSVGQKQLLALARVLVQTPQILILDEATANI 507

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1671187127 181 DaSFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:PRK10790  508 D-SGTEQAIQQALAAVREHTTLVVIAHRLSTIVE-ADTILVLHRGQ 551
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 33-288 4.12e-05

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 45.47  E-value: 4.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  33 GFRPAGSRRlEALQDVSIEITRGEFFSVIGPNGSGKS-TLLKIMAGIYRP----TSGRVSVTG--LLSP----------- 94
Cdd:PRK15134   14 AFRQQQTVR-TVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGesLLHAseqtlrgvrgn 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  95 -----FIELGVGFNAELTARENVFlsgAILGLSRSLVAERF-DDIVRFSE----------LSDFMDQklknYSSGMLVRL 158
Cdd:PRK15134   93 kiamiFQEPMVSLNPLHTLEKQLY---EVLSLHRGMRREAArGEILNCLDrvgirqaakrLTDYPHQ----LSGGERQRV 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 159 AFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGRprgiyspagaA 237
Cdd:PRK15134  166 MIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGR----------C 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127 238 VEYSRLNE-----EHA--NRLL-SDSKAAPTSATSSRPRIVSVEMLdgngQTTHAIQRG 288
Cdd:PRK15134  236 VEQNRAATlfsapTHPytQKLLnSEPSGDPVPLPEPASPLLDVEQL----QVAFPIRKG 290
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 44-223 6.14e-05

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 44.39  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIM--------------------AGIYRPTSGRVSV---TGLL----SPFI 96
Cdd:PRK14243   25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrlndlipgfrvegkvtfhgKNLYAPDVDPVEVrrrIGMVfqkpNPFP 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  97 ElgvgfnaelTARENVFLSGAILGLS---RSLVAERFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLV 173
Cdd:PRK14243  105 K---------SIYDNIAYGARINGYKgdmDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILM 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1671187127 174 DEVLAVGDASFQEKCFDVFRRFkKEGRTIIFVSHDMGSIQEFSDRVLILN 223
Cdd:PRK14243  176 DEPCSALDPISTLRIEELMHEL-KEQYTIIIVTHNMQQAARVSDMTAFFN 224
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 48-226 6.29e-05

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 45.22  E-value: 6.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  48 VSIEITRGEFFSVIGPNGSGKSTLLKIMAGiYRPTSGRVSVTGllspfIELG-------------VGFNAEL---TAREN 111
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTSLLNALLG-FLPYQGSLKING-----IELReldpeswrkhlswVGQNPQLphgTLRDN 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 112 VFLSGAilglsrSLVAERFDDIVRFSELSDFMDQ-------KLKNYSSGMLV----RLAFAVAIQAHADILLVDEVLAVG 180
Cdd:PRK11174  443 VLLGNP------DASDEQLQQALENAWVSEFLPLlpqgldtPIGDQAAGLSVgqaqRLALARALLQPCQLLLLDEPTASL 516

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127 181 DASFQEKcfdVFRRFKK--EGRTIIFVSHDMGSIQEFsDRVLILNHGR 226
Cdd:PRK11174  517 DAHSEQL---VMQALNAasRRQTTLMVTHQLEDLAQW-DQIWVMQDGQ 560
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 7-86 9.52e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 44.50  E-value: 9.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   7 ISIEHLTKVFRVPLErttsLKQLAaRGFrpaGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:PRK15064  307 IRFEQDKKLHRNALE----VENLT-KGF---DNGPL--FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV 376
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 43-148 1.07e-04

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 43.63  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  43 EALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGI--YRPTSGRVSVTGL----LSPFIELGVG------FNAELTARE 110
Cdd:PRK09580   15 AILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKdlleLSPEDRAGEGifmafqYPVEIPGVS 94

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1671187127 111 N-VFLSGAILGLSRSLVAERFDdivRFsELSDFMDQKLK 148
Cdd:PRK09580   95 NqFFLQTALNAVRSYRGQEPLD---RF-DFQDLMEEKIA 129
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 45-225 1.41e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 44.17  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRV-----------------SVTGLLSPFIELGVGFNAELT 107
Cdd:PRK11147   19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIiyeqdlivarlqqdpprNVEGTVYDFVAEGIEEQAEYL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 108 ARENVFLSGAILGLSRSLVAE--------------RFDDivRFSE----LSDFMDQKLKNYSSGMLVRLAFAVAIQAHAD 169
Cdd:PRK11147   99 KRYHDISHLVETDPSEKNLNElaklqeqldhhnlwQLEN--RINEvlaqLGLDPDAALSSLSGGWLRKAALGRALVSNPD 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 170 ILLVDEV---LAVGDASFQEKcfdvfrrFKKEGR-TIIFVSHDMGSIQEFSDRVLILNHG 225
Cdd:PRK11147  177 VLLLDEPtnhLDIETIEWLEG-------FLKTFQgSIIFISHDRSFIRNMATRIVDLDRG 229
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 44-226 1.58e-04

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 42.87  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  44 ALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGL-------------LS-----PFIELGvgfnae 105
Cdd:cd03244    19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVdiskiglhdlrsrISiipqdPVLFSG------ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 106 lTARENV-----FLSGAILG-LSRSLVAErfddivRFSELSDFMDQKL----KNYSSGMLVRLAFAVAIQAHADILLVDE 175
Cdd:cd03244    93 -TIRSNLdpfgeYSDEELWQaLERVGLKE------FVESLPGGLDTVVeeggENLSVGQRQLLCLARALLRKSKILVLDE 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 176 VLAV----GDASFQEKcfdVFRRFKkeGRTIIFVSHDMGSIQEfSDRVLILNHGR 226
Cdd:cd03244   166 ATASvdpeTDALIQKT---IREAFK--DCTVLTIAHRLDTIID-SDRILVLDKGR 214
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
26-87 1.59e-04

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 43.06  E-value: 1.59e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1671187127  26 LKQLAARGFRPagsrrleaLQDVSIEITRGEFFSVI-GPNGSGKSTLLKIMAGIYRPTSGRVS 87
Cdd:COG3950     3 IKSLTIENFRG--------FEDLEIDFDNPPRLTVLvGENGSGKTTLLEAIALALSGLLSRLD 57
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 120-226 1.84e-04

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 43.17  E-value: 1.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 120 GLSRSLVAE---RFDDIVRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKCFDVFRRFK 196
Cdd:PRK09473  129 GMSKAEAFEesvRMLDAVKMPEARKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELK 208

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1671187127 197 KEGRT-IIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK09473  209 REFNTaIIMITHDLGVVAGICDKVLVMYAGR 239
PRK15177 PRK15177
Vi polysaccharide ABC transporter ATP-binding protein VexC;
56-226 2.05e-04

Vi polysaccharide ABC transporter ATP-binding protein VexC;


Pssm-ID: 185099 [Multi-domain]  Cd Length: 213  Bit Score: 42.35  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  56 EFFSVIGPNGSGKSTLLKIMAGIYRPTSGrvSVTGLLSPFIELGVG--FNAELTARENVFLSGAILGLSrslvAERFDDI 133
Cdd:PRK15177   14 EHIGILAAPGSGKTTLTRLLCGLDAPDEG--DFIGLRGDALPLGANsfILPGLTGEENARMMASLYGLD----GDEFSHF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 134 V-RFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASFQEKcFDVFRRFKKEGRTIIFVSHDMGSI 212
Cdd:PRK15177   88 CyQLTQLEQCYTDRVSEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLR-MQAALACQLQQKGLIVLTHNPRLI 166

                         170
                  ....*....|....
gi 1671187127 213 QEFSDRVLILNHGR 226
Cdd:PRK15177  167 KEHCHAFGVLLHGK 180
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 40-88 2.38e-04

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 43.48  E-value: 2.38e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1671187127   40 RRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV 88
Cdd:PTZ00265   396 KDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIII 444
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
35-229 4.61e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 42.21  E-value: 4.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  35 RPAGSRRLEA--------LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPF------IELGV 100
Cdd:PRK11288  251 RPLGEVRLRLdglkgpglREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIrsprdaIRAGI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 101 ----------GFNAELTARENVFLS--------GAIL--GLSRSLvAERFddIVRFSELSDFMDQKLKNYSSG-----ML 155
Cdd:PRK11288  331 mlcpedrkaeGIIPVHSVADNINISarrhhlraGCLInnRWEAEN-ADRF--IRSLNIKTPSREQLIMNLSGGnqqkaIL 407

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1671187127 156 VR-LAFAVaiqahaDILLVDEVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSIQEFSDRVLILNHGRPRG 229
Cdd:PRK11288  408 GRwLSEDM------KVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIAG 476
PLN03140 PLN03140
ABC transporter G family member; Provisional
 41-240 4.98e-04

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 42.53  E-value: 4.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   41 RLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGiyRPT----SGRVSVTGL---------LSPFIELGVGFNAELT 107
Cdd:PLN03140   892 RLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTggyiEGDIRISGFpkkqetfarISGYCEQNDIHSPQVT 969

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  108 ARENVFLSgAILGLSRSLVAE---RF-DDIVRFSELSDFMDQ-----KLKNYSSGMLVRLAFAVAIQAHADILLVDEVLA 178
Cdd:PLN03140   970 VRESLIYS-AFLRLPKEVSKEekmMFvDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTS 1048

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1671187127  179 VGDASFQEKCFDVFRRFKKEGRTIIFVSHDmGSIQEFS--DRVLILNHGrPRGIYS-PAG----AAVEY 240
Cdd:PLN03140  1049 GLDARAAAIVMRTVRNTVDTGRTVVCTIHQ-PSIDIFEafDELLLMKRG-GQVIYSgPLGrnshKIIEY 1115
PLN03073 PLN03073
ABC transporter F family; Provisional
 59-86 7.71e-04

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 41.77  E-value: 7.71e-04
                          10        20
                  ....*....|....*....|....*...
gi 1671187127  59 SVIGPNGSGKSTLLKIMAGIYRPTSGRV 86
Cdd:PLN03073  539 AMVGPNGIGKSTILKLISGELQPSSGTV 566
COG4637 COG4637
Predicted ATPase [General function prediction only];
26-72 7.84e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 41.45  E-value: 7.84e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1671187127  26 LKQLAARGFRpagsrrleALQDVSIEITRgefFSV-IGPNGSGKSTLL 72
Cdd:COG4637     2 ITRIRIKNFK--------SLRDLELPLGP---LTVlIGANGSGKSNLL 38
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-226 9.84e-04

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 41.21  E-value: 9.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   1 MQTDVAISIEHLTKVFRvplerttslkqlaargfrpAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKS----TLLKIMA 76
Cdd:COG4172     1 MMSMPLLSVEDLSVAFG-------------------QGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLP 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  77 GIYRPTSGRVSVTG--LLS-PFIEL--------GVGFNAELTA-----------RENVFLSGailGLS----RSLVAERF 130
Cdd:COG4172    62 DPAAHPSGSILFDGqdLLGlSERELrrirgnriAMIFQEPMTSlnplhtigkqiAEVLRLHR---GLSgaaaRARALELL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127 131 DDiVRFSELsdfmDQKLKNY----SSGMLVRLAFAVAIQAHADILLVDE---VLavgDASFQEKCFDVFRRFKKE-GRTI 202
Cdd:COG4172   139 ER-VGIPDP----ERRLDAYphqlSGGQRQRVMIAMALANEPDLLIADEpttAL---DVTVQAQILDLLKDLQRElGMAL 210

                         250       260
                  ....*....|....*....|....
gi 1671187127 203 IFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:COG4172   211 LLITHDLGVVRRFADRVAVMRQGE 234
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 45-77 1.52e-03

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 40.77  E-value: 1.52e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAG 77
Cdd:PRK10938  276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG 308
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 39-226 1.65e-03

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 40.61  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  39 SRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTG----LLSP-----------FI------- 96
Cdd:PRK10261  334 TREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGqridTLSPgklqalrrdiqFIfqdpyas 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  97 ---ELGVGFNAELTARENVFLSGAIlglSRSLVAERFDdivRFSELSDFMDQKLKNYSSGMLVRLAFAVAIQAHADILLV 173
Cdd:PRK10261  414 ldpRQTVGDSIMEPLRVHGLLPGKA---AAARVAWLLE---RVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIA 487

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1671187127 174 DEVLAVGDASFQEKCFDVFRRFKKE-GRTIIFVSHDMGSIQEFSDRVLILNHGR 226
Cdd:PRK10261  488 DEAVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQ 541
AAA_29 pfam13555
P-loop containing region of AAA domain;
46-72 1.92e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 36.42  E-value: 1.92e-03
                          10        20
                  ....*....|....*....|....*..
gi 1671187127  46 QDVSIEITRGEFFSVIGPNGSGKSTLL 72
Cdd:pfam13555  13 DGHTIPIDPRGNTLLTGPSGSGKSTLL 39
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 45-234 1.97e-03

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 40.70  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIEL-GVGFNAELTARENVFLSGAI---LG 120
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLhDLRFKITIIPQDPVLFSGSLrmnLD 1381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  121 LSRSLVAERFDDIVRFSELSDFMD---QKL--------KNYSSGMLVRLAFAVAIQAHADILLVDEVLAVGDASfQEKCF 189
Cdd:TIGR00957 1382 PFSQYSDEEVWWALELAHLKTFVSalpDKLdhecaeggENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE-TDNLI 1460

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1671187127  190 DVFRRFKKEGRTIIFVSHDMGSIQEFSdRVLILNHGRPRGIYSPA 234
Cdd:TIGR00957 1461 QSTIRTQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPS 1504
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 26-161 2.76e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 39.60  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  26 LKQLAARGFRpagsrrleALQDVSIEITRGefFSV-IGPNGSGKSTLLKIMAGIYRPTSGRV-------SVTGLLSPFIE 97
Cdd:COG3593     3 LEKIKIKNFR--------SIKDLSIELSDD--LTVlVGENNSGKSSILEALRLLLGPSSSRKfdeedfyLGDDPDLPEIE 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1671187127  98 LGVGFNAELTAR-ENVFLSGAILGLSRSLvaERFDDIVR--FSELSDFMDQKLKNYSSGMLVRLAFA 161
Cdd:COG3593    73 IELTFGSLLSRLlRLLLKEEDKEELEEAL--EELNEELKeaLKALNELLSEYLKELLDGLDLELELS 137
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 57-103 3.18e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 39.30  E-value: 3.18e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1671187127  57 FFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSVTGLLSPFIELGVGFN 103
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALVIGLTDERSRNGGIGGIPS 47
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 45-88 3.47e-03

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 39.73  E-value: 3.47e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1671187127  45 LQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIYRPTSGRVSV 88
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTK 511
AAA_23 pfam13476
AAA domain;
32-148 4.49e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 37.86  E-value: 4.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  32 RGFRPagsrrleaLQDVSIEITRGeFFSVIGPNGSGKSTLLK-IMAGIY--RPTSGRVSVTGLLSPFIELGVGFN----A 104
Cdd:pfam13476   4 ENFRS--------FRDQTIDFSKG-LTLITGPNGSGKTTILDaIKLALYgkTSRLKRKSGGGFVKGDIRIGLEGKgkayV 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1671187127 105 ELTARENVFLSGAILGLSRSLVAERFD-------DIVRFSELSDFMDQKLK 148
Cdd:pfam13476  75 EITFENNDGRYTYAIERSRELSKKKGKtkkkeilEILEIDELQQFISELLK 125
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 37-225 5.72e-03

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 38.94  E-value: 5.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127   37 AGSRRLeaLQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGiyRPTSGRVSVTGLLSPFIELGVGFN------------- 103
Cdd:TIGR00956  773 KEKRVI--LNNVDGWVKPGTLTALMGASGAGKTTLLNVLAE--RVTTGVITGGDRLVNGRPLDSSFQrsigyvqqqdlhl 848

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  104 AELTARENVFLSgAILGLSRSL-VAERF---DDIVRFSELSDFMDQKLKNYSSGMLV----RLAFAVAIQAHADILL-VD 174
Cdd:TIGR00956  849 PTSTVRESLRFS-AYLRQPKSVsKSEKMeyvEEVIKLLEMESYADAVVGVPGEGLNVeqrkRLTIGVELVAKPKLLLfLD 927

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1671187127  175 EVLAVGDASFQEKCFDVFRRFKKEGRTIIFVSHDMGSI--QEFsDRVLILNHG 225
Cdd:TIGR00956  928 EPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAIlfEEF-DRLLLLQKG 979
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 18-72 6.19e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 38.84  E-value: 6.19e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1671187127  18 VPLERTTSL-KQLAARGfrpagsRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLL 72
Cdd:TIGR00630 602 VPAERRPGNgKFLTLKG------ARENNLKNITVSIPLGLFTCITGVSGSGKSTLI 651
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 34-93 6.49e-03

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 37.63  E-value: 6.49e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671187127  34 FRPAGSRRLEALQDVSIEITRGEFFSVIGPNGSGKSTLLKIMAGIyrpTSGRVSVTGLLS 93
Cdd:cd03233    12 TTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANR---TEGNVSVEGDIH 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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