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Conserved domains on  [gi|1671062951|gb|TMF06533|]
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anthranilate phosphoribosyltransferase [Chloroflexi bacterium]

Protein Classification

anthranilate phosphoribosyltransferase( domain architecture ID 11425586)

anthranilate phosphoribosyltransferase catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 41-373 7.27e-93

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


:

Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 281.20  E-value: 7.27e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  41 RMRFFLREIGQGpragRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLL 120
Cdd:COG0547     1 MMKELLKKLAEG----KDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPLPDGDVV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 121 DIGSPYDGRKKSI----------------VVspasaivaaaagvpvvMHGEKHVGPKFGvpIGDVLEALGIDMDGEPEEV 184
Cdd:COG0547    77 DIVGTGGDGANTFnistaaafvaaaagvpVA----------------KHGNRSVSSKSG--SADVLEALGVNLDLSPEQV 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 185 ERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIV 264
Cdd:COG0547   139 ARCLEEAGIGFLFAPLFHPAMKHVAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVV 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 265 QGIEGNEDAPTSRPCRAFLWENGEKSELRIDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGGHRDLVLLNAGLRI 344
Cdd:COG0547   219 HGLDGLDEISLTGPTKVAELRDGEIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGEGGPARDAVLLNAAAAL 298

                         330       340
                  ....*....|....*....|....*....
gi 1671062951 345 WLAEGAASTAEGIEKAREVIDSGAAWAKL 373
Cdd:COG0547   299 YVAGKADSLAEGVELAREAIDSGAALAKL 327
 
Name Accession Description Interval E-value
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 41-373 7.27e-93

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 281.20  E-value: 7.27e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  41 RMRFFLREIGQGpragRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLL 120
Cdd:COG0547     1 MMKELLKKLAEG----KDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPLPDGDVV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 121 DIGSPYDGRKKSI----------------VVspasaivaaaagvpvvMHGEKHVGPKFGvpIGDVLEALGIDMDGEPEEV 184
Cdd:COG0547    77 DIVGTGGDGANTFnistaaafvaaaagvpVA----------------KHGNRSVSSKSG--SADVLEALGVNLDLSPEQV 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 185 ERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIV 264
Cdd:COG0547   139 ARCLEEAGIGFLFAPLFHPAMKHVAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVV 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 265 QGIEGNEDAPTSRPCRAFLWENGEKSELRIDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGGHRDLVLLNAGLRI 344
Cdd:COG0547   219 HGLDGLDEISLTGPTKVAELRDGEIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGEGGPARDAVLLNAAAAL 298

                         330       340
                  ....*....|....*....|....*....
gi 1671062951 345 WLAEGAASTAEGIEKAREVIDSGAAWAKL 373
Cdd:COG0547   299 YVAGKADSLAEGVELAREAIDSGAALAKL 327
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 55-375 3.22e-66

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 213.40  E-value: 3.22e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  55 AGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIaPKVKGLLDI----GspyDGRK 130
Cdd:PRK00188   12 EGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPV-PDPDDAVDIvgtgG---DGAN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 131 K-------SIVVSPasaivaaaagvpvvmhgekhvgpkFGVPI------------G--DVLEALGIDMDGEPEEVERSVE 189
Cdd:PRK00188   88 TfnistaaAFVAAA------------------------AGVKVakhgnrsvssksGsaDVLEALGVNLDLSPEQVARCLE 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 190 ETGLGFMrqarFVPQvF--ALR---DLRTEIALRTcfstvekIYNL-------AGASYSLLGLSHLPYAEKMLSAASQMG 257
Cdd:PRK00188  144 EVGIGFL----FAPL-YhpAMKhvaPVRKELGIRT-------IFNLlgpltnpARPKRQLIGVYSPDLLEPMAEVLKRLG 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 258 FRRIMIVQGIEGNEDAPTSRPCRAFLWENGEKSELRIDPAEYTLQPATAEEMAGGGAAENASIAEAVLSG-EPGGHRDLV 336
Cdd:PRK00188  212 SKRALVVHGSDGLDEISLTGPTTVAELKDGEIREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLQGkGPGAARDAV 291

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1671062951 337 LLNAGLRIWLAEGAASTAEGIEKAREVIDSGAAWAKLDQ 375
Cdd:PRK00188  292 LLNAAAALYVAGKADDLKEGVELAREAIDSGAALAKLEE 330
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 56-376 2.70e-63

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 205.58  E-value: 2.70e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  56 GRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPK-VKGLLDI-GSPYDGrKKSI 133
Cdd:TIGR01245   7 GKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRpPEDLVDIvGTGGDG-ANTI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 134 VVSPASAIVAAAAGVPVVMHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRT 213
Cdd:TIGR01245  86 NISTASAFVAAAAGVKVAKHGNRSVSSKSGS--ADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAPVRR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 214 EIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSRPCRAFLWENGEKSELR 293
Cdd:TIGR01245 164 ELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIREYT 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 294 IDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGG-HRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAAWAK 372
Cdd:TIGR01245 244 LDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKGSGaKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAAAEK 323


                  ....
gi 1671062951 373 LDQV 376
Cdd:TIGR01245 324 LEEL 327
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 152-369 9.55e-40

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 141.66  E-value: 9.55e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 152 MHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLA 231
Cdd:pfam00591  37 KHGNRSVSSKSGS--ADVLEALGINLDLTPEQVRKLLDEVGVGFLFAPNYHPAMKHVAPVRRELGIRTVFNLLGPLINPA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 232 GASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSRpcrAFLWE--NGEKSELRIDPAEYTLQPATAEEM 309
Cdd:pfam00591 115 RVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHGDGLDEASLLGK---TTVAElkDGEITEYTLTPEDFGLGRATLEAL 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671062951 310 AGGGAAENASIAEAVLSGEPGG-HRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAA 369
Cdd:pfam00591 192 EGGSPKENADILKGVLGGKGSAaHRDLVALNAGAALYLAGKADSLKEGVAKALEVIDSGKA 252
 
Name Accession Description Interval E-value
TrpD COG0547
Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and ...
 41-373 7.27e-93

Anthranilate phosphoribosyltransferase, glycosyltransferase domain [Amino acid transport and metabolism]; Anthranilate phosphoribosyltransferase, glycosyltransferase domain is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440313 [Multi-domain]  Cd Length: 327  Bit Score: 281.20  E-value: 7.27e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  41 RMRFFLREIGQGpragRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLL 120
Cdd:COG0547     1 MMKELLKKLAEG----KDLTREEAREAMRQIMSGEATPAQIGAFLTALRMKGETVEEIAGFADAMRELAVPVPLPDGDVV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 121 DIGSPYDGRKKSI----------------VVspasaivaaaagvpvvMHGEKHVGPKFGvpIGDVLEALGIDMDGEPEEV 184
Cdd:COG0547    77 DIVGTGGDGANTFnistaaafvaaaagvpVA----------------KHGNRSVSSKSG--SADVLEALGVNLDLSPEQV 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 185 ERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIV 264
Cdd:COG0547   139 ARCLEEAGIGFLFAPLFHPAMKHVAPVRKELGVRTIFNLLGPLTNPAGPKRQLLGVYHPELVEPLAEVLQLLGVKRALVV 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 265 QGIEGNEDAPTSRPCRAFLWENGEKSELRIDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGGHRDLVLLNAGLRI 344
Cdd:COG0547   219 HGLDGLDEISLTGPTKVAELRDGEIEEYTLDPEDFGLPRAPLEDLRGGDAEENAEILRAVLAGEGGPARDAVLLNAAAAL 298

                         330       340
                  ....*....|....*....|....*....
gi 1671062951 345 WLAEGAASTAEGIEKAREVIDSGAAWAKL 373
Cdd:COG0547   299 YVAGKADSLAEGVELAREAIDSGAALAKL 327
trpD PRK00188
anthranilate phosphoribosyltransferase; Provisional
 55-375 3.22e-66

anthranilate phosphoribosyltransferase; Provisional


Pssm-ID: 234682 [Multi-domain]  Cd Length: 339  Bit Score: 213.40  E-value: 3.22e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  55 AGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIaPKVKGLLDI----GspyDGRK 130
Cdd:PRK00188   12 EGEDLSEEEAEELMDAIMSGEATPAQIAAFLTALRVKGETVDEIAGAARAMREHAVPV-PDPDDAVDIvgtgG---DGAN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 131 K-------SIVVSPasaivaaaagvpvvmhgekhvgpkFGVPI------------G--DVLEALGIDMDGEPEEVERSVE 189
Cdd:PRK00188   88 TfnistaaAFVAAA------------------------AGVKVakhgnrsvssksGsaDVLEALGVNLDLSPEQVARCLE 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 190 ETGLGFMrqarFVPQvF--ALR---DLRTEIALRTcfstvekIYNL-------AGASYSLLGLSHLPYAEKMLSAASQMG 257
Cdd:PRK00188  144 EVGIGFL----FAPL-YhpAMKhvaPVRKELGIRT-------IFNLlgpltnpARPKRQLIGVYSPDLLEPMAEVLKRLG 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 258 FRRIMIVQGIEGNEDAPTSRPCRAFLWENGEKSELRIDPAEYTLQPATAEEMAGGGAAENASIAEAVLSG-EPGGHRDLV 336
Cdd:PRK00188  212 SKRALVVHGSDGLDEISLTGPTTVAELKDGEIREYTLTPEDFGLPRAPLEDLRGGDPEENAAILRAVLQGkGPGAARDAV 291

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1671062951 337 LLNAGLRIWLAEGAASTAEGIEKAREVIDSGAAWAKLDQ 375
Cdd:PRK00188  292 LLNAAAALYVAGKADDLKEGVELAREAIDSGAALAKLEE 330
PRK14607 PRK14607
bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;
55-377 1.32e-63

bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase;


Pssm-ID: 237764 [Multi-domain]  Cd Length: 534  Bit Score: 211.88  E-value: 1.32e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  55 AGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLLDI-GSPYDGrKKSI 133
Cdd:PRK14607  204 EGEDLSFEEAEDVMEDITDGNATDAQIAGFLTALRMKGETADELAGFASVMREKSRHIPAPSPRTVDTcGTGGDG-FGTF 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 134 VVSPASAIVAAAAGVPVVMHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRT 213
Cdd:PRK14607  283 NISTTSAFVVAAAGVPVAKHGNRAVSSKSGS--ADVLEALGVKLEMTPEEAASVLRETGFSFLFAPLFHPAMKHAAPARR 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 214 EIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSRPCRAFLWENGEKSELR 293
Cdd:PRK14607  361 ELGIRTAFNLLGPLTNPARVKYQIVGVFDPSYAEPLAQALQRLGTERAMVVSGIDGYDEISTCGPTQILELEDGEIVTYT 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 294 IDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEP-GGHRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAAWAK 372
Cdd:PRK14607  441 FDPEELGLKRVDPEELKGGDPQENYRLAEDVLKGEPrRPQRDAVALNAGAALYLVGEADSIKEGVGKALDLIDDGRAYKK 520


                  ....*
gi 1671062951 373 LDQVR 377
Cdd:PRK14607  521 LEEVM 525
PRK07394 PRK07394
hypothetical protein; Provisional
 40-378 1.71e-63

hypothetical protein; Provisional


Pssm-ID: 168934 [Multi-domain]  Cd Length: 342  Bit Score: 206.30  E-value: 1.71e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  40 ERMRFFLREIGQGPRAGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKG- 118
Cdd:PRK07394    3 ERFRELLKKVGSGEHTSKDLTREEAADALKLMLLGEATPAQIGAFLIAHRIKRPTPEELAGMLDTYDELGPKLQSPSNQr 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 119 -LLDIGSPYDGRKKSIVVSPASAIVAAAAGVPVVMHGEKHVGPKFGVPIGDVLEALGIDMDGEP-EEVERSVEETGLGFM 196
Cdd:PRK07394   83 pPIVFGMPYDGRSRTAPIYPLTALILAAAGQPVVLHGGDRMPTKYGVPLVELWQGLGVDLTGLSlEQVQEGFEQTGLAFI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 197 RQARFVPQVFALRDLRTEIALRTCFSTVEKIYN-LAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPT 275
Cdd:PRK07394  163 YQPDHFPLAESLIPYRDEIGKRPPLATLELIWTpHQGDHHLVSGFVHPPTEARAWEALELRGETNFTTVKGLEGSCDLPI 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 276 SRPCRAFLWENGEKSELRIDPAEYTLQPAtaeEMAGGGAAENASIAEAVLSGEPGGHRDLVLLNAGLRIWLAEGAASTAE 355
Cdd:PRK07394  243 SRTAIIGRVQNGHFERLILHPRDYGCGGK---DVPWESTEEWLEQAQAALNGEPGPLTQALIWNGGFYLWRAGISSSLEE 319

                         330       340
                  ....*....|....*....|...
gi 1671062951 356 GIEKAREVIDSGAAWAKLDQVRT 378
Cdd:PRK07394  320 GIEKAEELLNSGKALQKLQQLIA 342
trpD TIGR01245
anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, ...
 56-376 2.70e-63

anthranilate phosphoribosyltransferase; In many widely different species, including E. coli, Thermotoga maritima, and Archaeoglobus fulgidus, this enzymatic domain (anthranilate phosphoribosyltransferase) is found C-terminal to glutamine amidotransferase; the fusion protein is designated anthranilate synthase component II (EC 4.1.3.27) [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273522 [Multi-domain]  Cd Length: 330  Bit Score: 205.58  E-value: 2.70e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  56 GRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPK-VKGLLDI-GSPYDGrKKSI 133
Cdd:TIGR01245   7 GKDLSRDEAEQLMKEIMSGEASPAQIAAILTALRIKGETPEEITGFAKAMREHAVKVPGRpPEDLVDIvGTGGDG-ANTI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 134 VVSPASAIVAAAAGVPVVMHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRT 213
Cdd:TIGR01245  86 NISTASAFVAAAAGVKVAKHGNRSVSSKSGS--ADVLEALGVNLDLGPEKVARSLEETGIGFLFAPLYHPAMKHVAPVRR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 214 EIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSRPCRAFLWENGEKSELR 293
Cdd:TIGR01245 164 ELGVRTVFNLLGPLTNPARPKYQVIGVYDPDLVEVMAEALKNLGVKRALVVHGDDGLDEISLTGPTTVAELKDGEIREYT 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 294 IDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGG-HRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAAWAK 372
Cdd:TIGR01245 244 LDPEDFGLPRAPLEELAGGSPEENAEILRDILRGKGSGaKRDIVALNAAAALYVAGRASDLKEGVELALEAIDSGAAAEK 323


                  ....
gi 1671062951 373 LDQV 376
Cdd:TIGR01245 324 LEEL 327
PLN02641 PLN02641
anthranilate phosphoribosyltransferase
 56-375 1.14e-50

anthranilate phosphoribosyltransferase


Pssm-ID: 215345 [Multi-domain]  Cd Length: 343  Bit Score: 173.00  E-value: 1.14e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  56 GRDLTREEAREAMSLILsQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIaPKVKGLLDI-GSPYDGrKKSIV 134
Cdd:PLN02641   14 GTDLTEEEAEAALDFLL-DDADEAQISAFLVLLRAKGETFEEIAGLARAMIKRARKV-DGLVDAVDIvGTGGDG-ANTVN 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 135 VSPASAIVAAAAGVPVVMHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRTE 214
Cdd:PLN02641   91 ISTGSSILAAACGAKVAKQGNRSSSSACGS--ADVLEALGVAIDLGPEGVKRCVEEVGIGFMMAPKYHPAMKIVAPVRKK 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 215 IALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSrPCRAFLWENGEKSELRI 294
Cdd:PLN02641  169 LKVKTVFNILGPMLNPARVPHAVVGVYHESLVEKMAKALQRFGMKRALVVHSEGLDEMSPLG-PGDVLEVTPEKIEEFSF 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 295 DPAEYTLQPATAEEMAGGGAAENASIAEAVLSGEPGGHRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAA----- 369
Cdd:PLN02641  248 DPLDFGIPRCTLEDLRGGDPDYNAKVLRDVLSGEKGAIADALILNAAAALLVSGLAKTLAEGVALARETQESGKAiktld 327


                  ....*..
gi 1671062951 370 -WAKLDQ 375
Cdd:PLN02641  328 sWIKISQ 334
Glycos_transf_3 pfam00591
Glycosyl transferase family, a/b domain; This family includes anthranilate ...
 152-369 9.55e-40

Glycosyl transferase family, a/b domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 459860 [Multi-domain]  Cd Length: 253  Bit Score: 141.66  E-value: 9.55e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 152 MHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLA 231
Cdd:pfam00591  37 KHGNRSVSSKSGS--ADVLEALGINLDLTPEQVRKLLDEVGVGFLFAPNYHPAMKHVAPVRRELGIRTVFNLLGPLINPA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 232 GASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQGIEGNEDAPTSRpcrAFLWE--NGEKSELRIDPAEYTLQPATAEEM 309
Cdd:pfam00591 115 RVKRQVLGVYSKELAEGLAEVLKDLGRERAAVVHGDGLDEASLLGK---TTVAElkDGEITEYTLTPEDFGLGRATLEAL 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1671062951 310 AGGGAAENASIAEAVLSGEPGG-HRDLVLLNAGLRIWLAEGAASTAEGIEKAREVIDSGAA 369
Cdd:pfam00591 192 EGGSPKENADILKGVLGGKGSAaHRDLVALNAGAALYLAGKADSLKEGVAKALEVIDSGKA 252
PRK09071 PRK09071
glycosyl transferase family protein;
45-362 1.22e-36

glycosyl transferase family protein;


Pssm-ID: 181637 [Multi-domain]  Cd Length: 323  Bit Score: 135.42  E-value: 1.22e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  45 FLREIGQGPRAGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKglLDIGS 124
Cdd:PRK09071    7 YIRILGKGKRGRRSLTREEARQAMGMILDGEVEDDQLGAFLMLLRVKEETAEELAGFVEAIRERLQAPPLAVD--LDWPS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 125 pYDGRKK-----------------SIVvspasaivaaaagvpvvMHGekHVGPKFG-VPIGDVLEALGIDMDGEPEEVER 186
Cdd:PRK09071   85 -YAGKRRhlpwyllaakllaqngyRVL-----------------LHG--GGGHTAGrLYTEQLLEALGIPIARSWQEAEQ 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 187 SVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYNLAGASYSLLGLSHLPYAEKMLSAASQMGFRRIMIVQG 266
Cdd:PRK09071  145 ALEEHNIAYLPLEDFAPQLQRMIDLRNTLGLRSPINTLARLLNPLNAKASLQGIFHPGYQQLHREAARLLGDQNALVFKG 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 267 ----IEGNEDAPT----SRPCRAFLWENGEKSELRiDPAEYTLQPATAEEMaGGGAAENASIAEAVLSgepgghrdlvll 338
Cdd:PRK09071  225 eggeSERNPDVSTtlygSRNGEAWDEEWPALSEER-HVKPEELDPEQLLAV-WRGEEEDEYGENAVIA------------ 290

                         330       340
                  ....*....|....*....|....
gi 1671062951 339 NAGLRIWLAEGaASTAEGIEKARE 362
Cdd:PRK09071  291 TMALALWRGLN-QSREEAFEKAAQ 313
PRK09522 PRK09522
bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate ...
 59-373 5.80e-20

bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD;


Pssm-ID: 181927 [Multi-domain]  Cd Length: 531  Bit Score: 91.24  E-value: 5.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  59 LTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLLDI-GSPYDGrKKSIVVSP 137
Cdd:PRK09522  213 LSQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADIvGTGGDG-SNSINIST 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 138 ASAIVAAAAGVPVVMHGEKHVGPKFGVpiGDVLEALGIDMDGEPEEVERSVEETGLGFMRQARFVPQVFALRDLRTEIAL 217
Cdd:PRK09522  292 ASAFVAAACGLKVAKHGNRSVSSKSGS--SDLLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKT 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 218 RTCFSTVEKIYNLAGASYSLLGLSH----LPYAEKMlsaaSQMGFRRIMIVQGiEGNEDAPTSRPCRAFLWENGEKSELR 293
Cdd:PRK09522  370 RTLFNVLGPLINPAHPPLALIGVYSpelvLPIAETL----RVLGYQRAAVVHS-GGMDEVSLHAPTIVAELHDGEIKSYQ 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 294 IDPAEYTLQPATAEEMAGGGAAENASIAEAVLSGE-PGGHRDLVLLNAGLRIWLaEGAASTAEGIEKAREVIDSGAAWAK 372
Cdd:PRK09522  445 LTAEDFGLTPYHQEQLAGGTPEENRDILTRLLQGKgDAAHEAAVAANVAMLMRL-HGHEDLQANAQTVLEVLRSGSAYDR 523


                  .
gi 1671062951 373 L 373
Cdd:PRK09522  524 V 524
PRK08136 PRK08136
glycosyl transferase family protein; Provisional
 45-328 6.35e-17

glycosyl transferase family protein; Provisional


Pssm-ID: 236160 [Multi-domain]  Cd Length: 317  Bit Score: 80.68  E-value: 6.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951  45 FLREIGQGPRAGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASARTIAPKVKGLLDIGS 124
Cdd:PRK08136    6 IIKEIGRGKNGARDLDRDTARALYGAMLDGRVPDLELGAILIALRIKGESEAEMLGFLDAMQAHTIPLTPPAGRPMPVVI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 125 P-YDG-RKKSIVVspasaivaaaagvpvvmhgekhvgP-------KFGVPI--------------GDVLEALGIDMDGEP 181
Cdd:PRK08136   86 PsYNGaRKQANLT------------------------PllalllaREGVPVlvhgvsedptrvtsAEIFEALGIPPTLHA 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 182 EEVERSVEETGLGFMRQARFVPQVFALRDLRTEIALRTCFSTVEKIYN--LAGASYSLLGLSHLPYAEKMLSAASQMGfR 259
Cdd:PRK08136  142 DQAQAKLAEGQPAFIPVGVLCPPLARLLALRWRMGVRNSAHTLAKLATpfAEGAALRLSSYTHPEYRDRLAEFFSDIG-A 220

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1671062951 260 RIMIVQGIEGNEDAPTSRpCRAFLWENGEKSELRIDPAEYTLqPATAEEMAGGGAAENASIAEAVLSGE 328
Cdd:PRK08136  221 RALLMRGTEGEVYANPRR-CPQIDWIHDGGCRVLVERQSGSA-DEPPELPAAKDAATTAAWIERVLAGE 287
Glycos_trans_3N pfam02885
Glycosyl transferase family, helical bundle domain; This family includes anthranilate ...
 54-109 1.49e-16

Glycosyl transferase family, helical bundle domain; This family includes anthranilate phosphoribosyltransferase (TrpD), thymidine phosphorylase. All these proteins can transfer a phosphorylated ribose substrate.


Pssm-ID: 460737 [Multi-domain]  Cd Length: 63  Bit Score: 73.18  E-value: 1.49e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1671062951  54 RAGRDLTREEAREAMSLILSQQATPAQAGGFLLVQRYKGESPEELIGFAEAVRASA 109
Cdd:pfam02885   8 RDGEDLTREEARAAMDGIMSGEATDAQIAAFLMALRMKGETAEEIAGLARAMRESG 63
PRK04350 PRK04350
thymidine phosphorylase; Provisional
 323-375 3.68e-04

thymidine phosphorylase; Provisional


Pssm-ID: 235289 [Multi-domain]  Cd Length: 490  Bit Score: 42.49  E-value: 3.68e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1671062951 323 AVLSGEPGGHRDLV---LLNAGLRIWLAeGAASTAEGIEKAREVIDSGAAWAKLDQ 375
Cdd:PRK04350  333 AVLENDPDAPNDLReksLRLAGILLEMG-GVAPGGEGYALAREILESGKALEKFQE 387
PLN02790 PLN02790
transketolase
 250-364 7.80e-03

transketolase


Pssm-ID: 215424 [Multi-domain]  Cd Length: 654  Bit Score: 38.46  E-value: 7.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1671062951 250 LSAASQMGFRRIMIVQGIEGNEDAPTSRPCRAFlwengekSELRIDPAEYTLQPATAEEMAG------------------ 311
Cdd:PLN02790  438 LSALSEAGVIYVMTHDSIGLGEDGPTHQPIEHL-------ASLRAMPNILMLRPADGNETAGaykvavtnrkrptvlals 510

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1671062951 312 --------GGAAENASIAEAVLSGEPGGHR-DLVLLNAGLRIWLAEGAASTAEGIEKAREVI 364
Cdd:PLN02790  511 rqkvpnlpGTSIEGVEKGGYVISDNSSGNKpDLILIGTGSELEIAAKAAKELRKEGKKVRVV 572
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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