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Conserved domains on  [gi|1670170663|gb|TLY40148|]
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VacJ family lipoprotein, partial [Nitrospirae bacterium]

Protein Classification

VacJ family lipoprotein( domain architecture ID 10006733)

VacJ family lipoprotein similar to phospholipid-binding lipoprotein MlaA, which actively prevents phospholipid accumulation at the cell surface

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MlaA COG2853
Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
130-242 2.04e-60

Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442101  Cd Length: 236  Bit Score: 190.81  E-value: 2.04e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 130 EEYDPWESFNSRTFEFNRKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINT 209
Cdd:COG2853    31 DPNDPLEPFNRAMFAFNDVLDRYVLRPVAKGYRAVVPDPVRTGVSNFFSNLGEPVSFVNNLLQGKPKDAGTDLGRFLINT 110
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1670170663 210 TVGIGGLFDPAKDlLGMETPDEDFGQTLGAYGV 242
Cdd:COG2853   111 TFGLGGLFDVASE-MGLPKHDEDFGQTLGVWGV 142
 
Name Accession Description Interval E-value
MlaA COG2853
Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
130-242 2.04e-60

Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442101  Cd Length: 236  Bit Score: 190.81  E-value: 2.04e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 130 EEYDPWESFNSRTFEFNRKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINT 209
Cdd:COG2853    31 DPNDPLEPFNRAMFAFNDVLDRYVLRPVAKGYRAVVPDPVRTGVSNFFSNLGEPVSFVNNLLQGKPKDAGTDLGRFLINT 110
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1670170663 210 TVGIGGLFDPAKDlLGMETPDEDFGQTLGAYGV 242
Cdd:COG2853   111 TFGLGGLFDVASE-MGLPKHDEDFGQTLGVWGV 142
MlaA pfam04333
MlaA lipoprotein; MlaA is a component of the Mla pathway, an ABC transport system that ...
131-243 2.66e-60

MlaA lipoprotein; MlaA is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. MlaA is required for the intercellular spreading of Shigella flexneri. It is attached to the outer membrane by a lipid anchor.


Pssm-ID: 461265  Cd Length: 194  Bit Score: 189.24  E-value: 2.66e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 131 EYDPWESFNSRTFEFNRKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINTT 210
Cdd:pfam04333   1 VNDPLEGFNRAMFAFNDGLDRYVLKPVAKGYRAVVPDPVRTGVSNFFSNLGEPVSFVNNLLQGKFKKAGVDLGRFLINTT 80
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1670170663 211 VGIGGLFDPAKDlLGMETPDEDFGQTLGAYGVN 243
Cdd:pfam04333  81 LGLGGLFDVASA-LGLPKHDEDFGQTLGVWGVG 112
PRK15091 PRK15091
phospholipid-binding lipoprotein MlaA;
133-242 9.62e-19

phospholipid-binding lipoprotein MlaA;


Pssm-ID: 185047  Cd Length: 251  Bit Score: 82.82  E-value: 9.62e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 133 DPWESFNSRTFEFN-RKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINTTV 211
Cdd:PRK15091   30 DPLEGFNRTMFNFNyNVLDPYVVRPVAVAWRDYVPQPARNGLSNFTGNLEEPASMVNYFLQGDPYQGMVHFTRFFLNTLL 109
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1670170663 212 GIGGLFDPAkdllGMETPD---ED---FGQTLGAYGV 242
Cdd:PRK15091  110 GMGGLIDVA----GMANPKlakEEphrFGSTLGHYGV 142
 
Name Accession Description Interval E-value
MlaA COG2853
Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
130-242 2.04e-60

Lipoprotein subunit MlaA of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442101  Cd Length: 236  Bit Score: 190.81  E-value: 2.04e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 130 EEYDPWESFNSRTFEFNRKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINT 209
Cdd:COG2853    31 DPNDPLEPFNRAMFAFNDVLDRYVLRPVAKGYRAVVPDPVRTGVSNFFSNLGEPVSFVNNLLQGKPKDAGTDLGRFLINT 110
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1670170663 210 TVGIGGLFDPAKDlLGMETPDEDFGQTLGAYGV 242
Cdd:COG2853   111 TFGLGGLFDVASE-MGLPKHDEDFGQTLGVWGV 142
MlaA pfam04333
MlaA lipoprotein; MlaA is a component of the Mla pathway, an ABC transport system that ...
131-243 2.66e-60

MlaA lipoprotein; MlaA is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. MlaA is required for the intercellular spreading of Shigella flexneri. It is attached to the outer membrane by a lipid anchor.


Pssm-ID: 461265  Cd Length: 194  Bit Score: 189.24  E-value: 2.66e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 131 EYDPWESFNSRTFEFNRKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINTT 210
Cdd:pfam04333   1 VNDPLEGFNRAMFAFNDGLDRYVLKPVAKGYRAVVPDPVRTGVSNFFSNLGEPVSFVNNLLQGKFKKAGVDLGRFLINTT 80
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1670170663 211 VGIGGLFDPAKDlLGMETPDEDFGQTLGAYGVN 243
Cdd:pfam04333  81 LGLGGLFDVASA-LGLPKHDEDFGQTLGVWGVG 112
PRK15091 PRK15091
phospholipid-binding lipoprotein MlaA;
133-242 9.62e-19

phospholipid-binding lipoprotein MlaA;


Pssm-ID: 185047  Cd Length: 251  Bit Score: 82.82  E-value: 9.62e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1670170663 133 DPWESFNSRTFEFN-RKFDKYVLKPVATGYEWVMPDPLERGITNFFHNVRFVPRLMNNLFQAKFKGAGVELGRFLINTTV 211
Cdd:PRK15091   30 DPLEGFNRTMFNFNyNVLDPYVVRPVAVAWRDYVPQPARNGLSNFTGNLEEPASMVNYFLQGDPYQGMVHFTRFFLNTLL 109
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1670170663 212 GIGGLFDPAkdllGMETPD---ED---FGQTLGAYGV 242
Cdd:PRK15091  110 GMGGLIDVA----GMANPKlakEEphrFGSTLGHYGV 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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