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Conserved domains on  [gi|1615386066|gb|TGX91323|]
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phage baseplate assembly protein V [Escherichia coli]

Protein Classification

phage baseplate assembly protein V( domain architecture ID 10008608)

phage baseplate assembly protein V forms the small spikes on the baseplate that plug the end of the tube before DNA ejection and form a channel perforating the host membrane during ejection

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gpV COG4540
Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];
11-184 5.11e-71

Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];


:

Pssm-ID: 443606 [Multi-domain]  Cd Length: 167  Bit Score: 212.46  E-value: 5.11e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  11 LITNLIRTGVVTEVDRENWLCRVKTGDLETNWINWLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQFAP 90
Cdd:COG4540     1 RLANLIRTGTVAAVDADPGRVRVRTGDLLTDWLPWLTPRAGGVRDWWPPSVGEQVLLLSPGGDLEDGVVLPGLYSDADPA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  91 PSTSADACVTEHPDGGWFEYEPASGRWYVRGIKSMVIEAADNITMKTSEFVLEADrtrinsEVVINGGVTQgGGAMSSNG 170
Cdd:COG4540    81 PSDSPDAHVTRFPDGAVIEYDRATGALTVTGIGTATVTASGSVTLTAPTVTLDAP------VVTITGNVTV-SGDVTAGG 153

                         170
                  ....*....|....
gi 1615386066 171 IVVDAHQHTGVLKG 184
Cdd:COG4540   154 VSLNNHTHGGVQSG 167
 
Name Accession Description Interval E-value
gpV COG4540
Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];
11-184 5.11e-71

Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];


Pssm-ID: 443606 [Multi-domain]  Cd Length: 167  Bit Score: 212.46  E-value: 5.11e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  11 LITNLIRTGVVTEVDRENWLCRVKTGDLETNWINWLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQFAP 90
Cdd:COG4540     1 RLANLIRTGTVAAVDADPGRVRVRTGDLLTDWLPWLTPRAGGVRDWWPPSVGEQVLLLSPGGDLEDGVVLPGLYSDADPA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  91 PSTSADACVTEHPDGGWFEYEPASGRWYVRGIKSMVIEAADNITMKTSEFVLEADrtrinsEVVINGGVTQgGGAMSSNG 170
Cdd:COG4540    81 PSDSPDAHVTRFPDGAVIEYDRATGALTVTGIGTATVTASGSVTLTAPTVTLDAP------VVTITGNVTV-SGDVTAGG 153

                         170
                  ....*....|....
gi 1615386066 171 IVVDAHQHTGVLKG 184
Cdd:COG4540   154 VSLNNHTHGGVQSG 167
phage_P2_V TIGR01644
phage baseplate assembly protein V; This model describes a family of phage (and bacteriocin) ...
 8-189 1.78e-69

phage baseplate assembly protein V; This model describes a family of phage (and bacteriocin) proteins related to the phage P2 V gene product, which forms the small spike at the tip of the tail. Homologs in general are annotated as baseplate assembly protein V. At least one member is encoded within a region of Pectobacterium carotovorum (Erwinia carotovora) described as a bacteriocin, a phage tail-derived module able to kill bacteria closely related to the host strain. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273729 [Multi-domain]  Cd Length: 190  Bit Score: 209.57  E-value: 1.78e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066   8 IMRLITNLIRTGVVTEVDRENWLCRVKTGDLETNWINWLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQ 87
Cdd:TIGR01644   1 LMRGLRNLIRRGVVAEVDDAAGRVRVLQGELLTGWLPWLVERAGNYRTWSAPSVGEQVLVLSPGGQLDTGVVLPGVYSDD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  88 FAPPSTSADACVTEHPDGGWFEYEPASGRWYVRGIKSMVIEAADNITMKTSEFVLEAD---RTRINSEVVINGGVTQGG- 163
Cdd:TIGR01644  81 FRPPSLSAGDTVTYFADGARIEYDKAAHALTVCGIKTVYLDAGDGTTVTVDAPQITFTggvTTLKGPETVITGNVTIDGt 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1615386066 164 ----GAMSSNGIVVDAHQHTGVLKGGDTTG 189
Cdd:TIGR01644 161 lhtgGDASSNGISLDKHGHTGVHSGGTTSG 190
Phage_base_V pfam04717
Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage ...
 17-84 3.05e-16

Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage baseplate assembly proteins responsible for forming the small spike at the end of the tail or bacterial pathogenic needle-shaft. This entry represents the OB fold part of the structure. This structure contains an unusual extra beta hairpin that forms the foundation of the spike protein's beta helix.


Pssm-ID: 428084 [Multi-domain]  Cd Length: 75  Bit Score: 69.91  E-value: 3.05e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1615386066  17 RTGVVTEVDRENWLCRVK------TGDLETNWINWLTLRAGNAR-TWWKPSEGEQVVLLSLGGNLETAFALPAVY 84
Cdd:pfam04717   1 RLGVVTDVDDPDKLGRVKvgvpwlTDEEESGWARWAAPRAGAGRgLWFLPEVGEQVLVLFEGGDPSRPVVLGGLW 75
 
Name Accession Description Interval E-value
gpV COG4540
Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];
11-184 5.11e-71

Phage P2 baseplate assembly protein gpV [Mobilome: prophages, transposons];


Pssm-ID: 443606 [Multi-domain]  Cd Length: 167  Bit Score: 212.46  E-value: 5.11e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  11 LITNLIRTGVVTEVDRENWLCRVKTGDLETNWINWLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQFAP 90
Cdd:COG4540     1 RLANLIRTGTVAAVDADPGRVRVRTGDLLTDWLPWLTPRAGGVRDWWPPSVGEQVLLLSPGGDLEDGVVLPGLYSDADPA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  91 PSTSADACVTEHPDGGWFEYEPASGRWYVRGIKSMVIEAADNITMKTSEFVLEADrtrinsEVVINGGVTQgGGAMSSNG 170
Cdd:COG4540    81 PSDSPDAHVTRFPDGAVIEYDRATGALTVTGIGTATVTASGSVTLTAPTVTLDAP------VVTITGNVTV-SGDVTAGG 153

                         170
                  ....*....|....
gi 1615386066 171 IVVDAHQHTGVLKG 184
Cdd:COG4540   154 VSLNNHTHGGVQSG 167
phage_P2_V TIGR01644
phage baseplate assembly protein V; This model describes a family of phage (and bacteriocin) ...
 8-189 1.78e-69

phage baseplate assembly protein V; This model describes a family of phage (and bacteriocin) proteins related to the phage P2 V gene product, which forms the small spike at the tip of the tail. Homologs in general are annotated as baseplate assembly protein V. At least one member is encoded within a region of Pectobacterium carotovorum (Erwinia carotovora) described as a bacteriocin, a phage tail-derived module able to kill bacteria closely related to the host strain. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273729 [Multi-domain]  Cd Length: 190  Bit Score: 209.57  E-value: 1.78e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066   8 IMRLITNLIRTGVVTEVDRENWLCRVKTGDLETNWINWLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQ 87
Cdd:TIGR01644   1 LMRGLRNLIRRGVVAEVDDAAGRVRVLQGELLTGWLPWLVERAGNYRTWSAPSVGEQVLVLSPGGQLDTGVVLPGVYSDD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1615386066  88 FAPPSTSADACVTEHPDGGWFEYEPASGRWYVRGIKSMVIEAADNITMKTSEFVLEAD---RTRINSEVVINGGVTQGG- 163
Cdd:TIGR01644  81 FRPPSLSAGDTVTYFADGARIEYDKAAHALTVCGIKTVYLDAGDGTTVTVDAPQITFTggvTTLKGPETVITGNVTIDGt 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1615386066 164 ----GAMSSNGIVVDAHQHTGVLKGGDTTG 189
Cdd:TIGR01644 161 lhtgGDASSNGISLDKHGHTGVHSGGTTSG 190
Phage_base_V pfam04717
Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage ...
 17-84 3.05e-16

Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage baseplate assembly proteins responsible for forming the small spike at the end of the tail or bacterial pathogenic needle-shaft. This entry represents the OB fold part of the structure. This structure contains an unusual extra beta hairpin that forms the foundation of the spike protein's beta helix.


Pssm-ID: 428084 [Multi-domain]  Cd Length: 75  Bit Score: 69.91  E-value: 3.05e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1615386066  17 RTGVVTEVDRENWLCRVK------TGDLETNWINWLTLRAGNAR-TWWKPSEGEQVVLLSLGGNLETAFALPAVY 84
Cdd:pfam04717   1 RLGVVTDVDDPDKLGRVKvgvpwlTDEEESGWARWAAPRAGAGRgLWFLPEVGEQVLVLFEGGDPSRPVVLGGLW 75
Apex pfam18946
GpV Apex motif; This entry represents a short motif found at the C-terminus of Phage gpV ...
 170-192 2.16e-05

GpV Apex motif; This entry represents a short motif found at the C-terminus of Phage gpV proteins. These proteins act as a spike for piercing the host membrane. The apex motif contains a conserved HXH motif that coordinates an iron ion.


Pssm-ID: 436853  Cd Length: 23  Bit Score: 39.66  E-value: 2.16e-05
                          10        20
                  ....*....|....*....|...
gi 1615386066 170 GIVVDAHQHTGVLKGGDTTGGPV 192
Cdd:pfam18946   1 GVSLGTHTHGGVQDGGGTTGGPQ 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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