NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1586794401|gb|TCB63283|]
View 

ABC transporter permease [Rhizobium leguminosarum bv. viciae]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-269 4.37e-84

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 253.50  E-value: 4.37e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   1 MKTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGA 79
Cdd:COG1173     9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQdLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  80 GLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGqASPLVIALILGATSWAWGARVTRAETLSV 159
Cdd:COG1173    89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-PGLLNVILALGLTGWPGYARLVRAQVLSL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 160 KQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLG-GPRAISWGTMLYNAQkaSALSVg 238
Cdd:COG1173   168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGvQPPTPSWGTMLSEGR--NYLLT- 244

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1586794401 239 AWWDILTPCFALAFLGIGMSLLNFAVDEIAN 269
Cdd:COG1173   245 APWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-269 4.37e-84

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 253.50  E-value: 4.37e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   1 MKTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGA 79
Cdd:COG1173     9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQdLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  80 GLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGqASPLVIALILGATSWAWGARVTRAETLSV 159
Cdd:COG1173    89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-PGLLNVILALGLTGWPGYARLVRAQVLSL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 160 KQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLG-GPRAISWGTMLYNAQkaSALSVg 238
Cdd:COG1173   168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGvQPPTPSWGTMLSEGR--NYLLT- 244

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1586794401 239 AWWDILTPCFALAFLGIGMSLLNFAVDEIAN 269
Cdd:COG1173   245 APWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nikC PRK10417
nickel transporter permease NikC; Provisional
 6-229 1.12e-32

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 121.31  E-value: 1.12e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   6 RNRKALVGLVIIAFIVLVAIAAPLLTQYDPAA-RTGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLIT 84
Cdd:PRK10417    2 SRWSVRLALIIIALLALIALTSQWWLPYDPQAiDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  85 LVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQA-SPLVIALILgaTSWAWGARVTRAETLSVKQKD 163
Cdd:PRK10417   82 ALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGlTNVIIAIAL--SHWAWYARMVRSLVISLRQRE 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 164 FVKSAEMMGEPQWRIMTFEIFPNVIS---IVGINFIGSVIFAIiteATLEFLGLG-GPRAISWGTMLYNA 229
Cdd:PRK10417  160 FVLAARLSGAGHVRVFIDHLLPAVIPqllVLATLDIGHMMLHV---AGLSFLGLGvTAPTAEWGVMINDA 226
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 69-239 1.39e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.21  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  69 ARTSLAVGFGAGLLITLVGTALGIISGYRGGKTDEIISFFTNMV-------LVVPNLPLLLVLAAFIGQASPLVIALILG 141
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLlslpslvLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 142 ATSWAWGARVTRAETLSVKQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGGPRAIS 221
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*...
gi 1586794401 222 WGTMLYNAQKASALSVGA 239
Cdd:cd06261   161 TGLLLIFAILFPGDLGVA 178
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 1-46 2.66e-07

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 46.64  E-value: 2.66e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1586794401   1 MKTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPP 46
Cdd:pfam12911   7 WRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQdLSADLLPP 53
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-269 4.37e-84

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 253.50  E-value: 4.37e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   1 MKTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGA 79
Cdd:COG1173     9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQdLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  80 GLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGqASPLVIALILGATSWAWGARVTRAETLSV 159
Cdd:COG1173    89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-PGLLNVILALGLTGWPGYARLVRAQVLSL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 160 KQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLG-GPRAISWGTMLYNAQkaSALSVg 238
Cdd:COG1173   168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGvQPPTPSWGTMLSEGR--NYLLT- 244

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1586794401 239 AWWDILTPCFALAFLGIGMSLLNFAVDEIAN 269
Cdd:COG1173   245 APWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nikC PRK10417
nickel transporter permease NikC; Provisional
 6-229 1.12e-32

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 121.31  E-value: 1.12e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   6 RNRKALVGLVIIAFIVLVAIAAPLLTQYDPAA-RTGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLIT 84
Cdd:PRK10417    2 SRWSVRLALIIIALLALIALTSQWWLPYDPQAiDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  85 LVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQA-SPLVIALILgaTSWAWGARVTRAETLSVKQKD 163
Cdd:PRK10417   82 ALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGlTNVIIAIAL--SHWAWYARMVRSLVISLRQRE 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 164 FVKSAEMMGEPQWRIMTFEIFPNVIS---IVGINFIGSVIFAIiteATLEFLGLG-GPRAISWGTMLYNA 229
Cdd:PRK10417  160 FVLAARLSGAGHVRVFIDHLLPAVIPqllVLATLDIGHMMLHV---AGLSFLGLGvTAPTAEWGVMINDA 226
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 2-265 2.57e-30

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 115.70  E-value: 2.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   2 KTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAART-GRPHQPPSLD--HILGTTRIGQDVFARLIYGARTSLAVGFG 78
Cdd:PRK15406   31 RRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDwGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGGRISLMVGVA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  79 AGLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQaSPLVIALILGATSWAWGARVTRAETLS 158
Cdd:PRK15406  111 AALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQ-NILLIFVAIGMVSWLDMARIVRGQTLS 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 159 VKQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGGPRAI-SWGTMLYNAqkASALSV 237
Cdd:PRK15406  190 LKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLsSWGALLSDG--ANSMEV 267

                         250       260
                  ....*....|....*....|....*...
gi 1586794401 238 GAWWDIltpcFALAFLGIGMSLLNFAVD 265
Cdd:PRK15406  268 SPWLLL----FPAGFLVVTLFCFNFIGD 291
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
11-273 1.68e-29

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 113.37  E-value: 1.68e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  11 LVGLVIIAFIVLVAIAAPLLTQYDPAARTGRPH-QPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLITLVGTA 89
Cdd:PRK09881   34 VTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARlLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  90 LGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQA---SPLVIALIlgatSWAWGARVTRAETLSVKQKDFVK 166
Cdd:PRK09881  114 LGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSlfnAMLAIAIV----RIPFYVRLARGQALVVRQYTYVQ 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 167 SAEMMGEPQWRIMTFEIFPNVIS--IVGINF-IGSvifAIITEATLEFLGLGG-PRAISWGTMLYNAQKasaLSVGAWWD 242
Cdd:PRK09881  190 AAKTFGASRWHLISWHILRNSLPplIVQASLdIGS---AILMAATLGFIGLGAqQPSAEWGAMVANGRN---YVLDQWWY 263

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1586794401 243 ILTPCFALAFLGIGMSLLNFAVDEIANPRLR 273
Cdd:PRK09881  264 CAFPGAAILLTAVGFNLFGDGIRDLLDPKAG 294
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 6-230 1.22e-28

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 111.36  E-value: 1.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   6 RNRKALVGLVIIAFIVLVAIAAPLLTQYDPAA--RTGRPHQPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLI 83
Cdd:PRK15082   34 RQHVALVAGLFVLLLIVVAIFAPWIAPYDAENyfDYDALNAGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIG 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  84 TLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQASPLVIALILGATSWAWgARVTRAETLSVKQKD 163
Cdd:PRK15082  114 AAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAF-ARLVRGNTLVLKQQT 192

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1586794401 164 FVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGG-PRAISWGTMLYNAQ 230
Cdd:PRK15082  193 YIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAqPPTPEWGAMLNEAR 260
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 45-271 5.36e-28

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 110.24  E-value: 5.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  45 PPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVL 124
Cdd:COG4239   116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIIL 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 125 AAFIgQASPLVIALILGATSWAWGARVTRAETLSVKQKDFVKSAEMMGEPQWRIMTFEIFPN--VISIVGINFIgsVIFA 202
Cdd:COG4239   196 SSIF-QPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNamVATLTFLPFI--LSGA 272

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1586794401 203 IITEATLEFLGLG-GPRAISWGTMLynAQKASALSvgAWWDILTPCFALAFLgigMSLLNF---AVDEIANPR 271
Cdd:COG4239   273 ITTLTSLDFLGFGlPPGSPSLGELL--AQGKNNLQ--APWLGLSAFVVLALM---LSLLVFigeAVRDAFDPR 338
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
6-273 2.74e-26

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 104.86  E-value: 2.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   6 RNRKALVGLVIIAFIVLVAIAAPLLTQYDPAA--RTGRPHQPP-----SLDHILGTTRIGQDVFARLIYGARTSLAVGFG 78
Cdd:PRK10913   28 RNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEqfRDALLAPPVwqeggSWAHILGTDDVGRDVLSRLMYGARLSLLVGCL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  79 AGLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGqASPLVIALILGATSWAWGARVTRAETLS 158
Cdd:PRK10913  108 VVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFG-PSIVNAALALTFVALPHYVRLTRAAVLV 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 159 VKQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGG-PRAISWGTMLYNAQKasaLSV 237
Cdd:PRK10913  187 EVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAqPPTPEWGTMLSDVLQ---FAQ 263

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1586794401 238 GAWWDILTPCFALAFLGIGMSLLNFAVDEIANPRLR 273
Cdd:PRK10913  264 SAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLK 299
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 39-254 5.54e-14

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 71.17  E-value: 5.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  39 TGRPH-QPPSLDHILGTTRIGQDVFARLIYGARTSLAVGFGAGLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPN 117
Cdd:PRK15021  109 TDKPFpSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 118 LPLLLVLAAFIgqaSP-----LVIALILGatsWAWGARVTRAETLSVKQKDFVKSAEMMGEPQWRIMTFEIFPNVIsIVG 192
Cdd:PRK15021  189 LFLIILLSSVV---QPnfwwlLAITVLFG---WMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAM-VAT 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1586794401 193 INFIGSVIFAIITEAT-LEFLGLGGPR-AISWGTMLY---NAQKASALSVGAWWDILTPCFALAFLG 254
Cdd:PRK15021  262 LTFLPFILCSSITTLTsLDFLGFGLPLgSPSLGELLLqgkNNLQAPWLGITAFLSVAILLSLLIFIG 328
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 69-239 1.39e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.21  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  69 ARTSLAVGFGAGLLITLVGTALGIISGYRGGKTDEIISFFTNMV-------LVVPNLPLLLVLAAFIGQASPLVIALILG 141
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLlslpslvLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 142 ATSWAWGARVTRAETLSVKQKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGGPRAIS 221
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*...
gi 1586794401 222 WGTMLYNAQKASALSVGA 239
Cdd:cd06261   161 TGLLLIFAILFPGDLGVA 178
PRK15111 PRK15111
peptide ABC transporter permease SapC;
6-229 1.13e-09

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 58.17  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401   6 RNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPPSLDH------ILGTTRIGQDVFARLIYGArtslAVGFG 78
Cdd:PRK15111   25 SDALAMVGLYGCAGLALLCLFGGWLAPYGIDQQfLGYQLLPPSWSRygevsfFLGTDDLGRDVLSRLLSGA----APTVG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  79 AGLLITLVGTALGIISGYRGGKTDEIISFFTNMVLVVPNLPLLLVLA----AFIG-QASPLVIALILgatswAWGARVTR 153
Cdd:PRK15111  101 GAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAiivvAFAGpSLSHAMFAVWL-----ALLPRMVR 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 154 AETLSVK---QKDFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGGP-RAISWGTMLYNA 229
Cdd:PRK15111  176 SIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQlPSPEWGAMLGDS 255
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 72-275 4.11e-09

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 56.61  E-value: 4.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  72 SLAVGFGAGLLITLVGTALGIISG-YRGGKTDEIIS--------------------FFTNMVLVVPNLPLLLVLAAFIGQ 130
Cdd:COG0601    98 TLELALLALLLALLIGIPLGILAAlRRGSWLDRLITvlallgisipsfwlglllilLFAVKLGWLPVSGRVSPWEDFLDA 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 131 ASPLVI-ALILGATSWAWGARVTRAETLSVKQKDFVKSAEMMGEPQWRIMTFEIFPN----VISIVGINFIGSVIFAIIT 205
Cdd:COG0601   178 LRHLILpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNalipVVTVLGLQLGGLLGGAVVV 257

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1586794401 206 EATLEFLGLggpraiswGTMLYNAQKASalsvgawwDILTPCFALAFLGIGMSLLNFAVD---EIANPRLRTG 275
Cdd:COG0601   258 ETVFSWPGL--------GRLLVDAILNR--------DYPVVQGIVLLIAVLVVLVNLLVDllyALLDPRIRLG 314
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 1-46 2.66e-07

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 46.64  E-value: 2.66e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1586794401   1 MKTLLRNRKALVGLVIIAFIVLVAIAAPLLTQYDPAAR-TGRPHQPP 46
Cdd:pfam12911   7 WRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQdLSADLLPP 53
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 87-273 4.94e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.83  E-value: 4.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401  87 GTALGIISG-YRGGKTDEIISFFTNMVLVVPNLPLLLVLAAFIGQASP---LVIALILGATSWAWGARVTRAETLSVKQK 162
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILghgILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586794401 163 DFVKSAEMMGEPQWRIMTFEIFPNVISIVGINFIGSVIFAIITEATLEFLGLGGPraisWGTMLYNAQKASALSVgawwd 242
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPG----LGLLLIEAILGYDYPE----- 151

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1586794401 243 ILTPCFALAFLGIGMSLLNFAVDEIANPRLR 273
Cdd:pfam00528 152 IQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH