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Conserved domains on  [gi|1586791995|gb|TCB60877|]
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carbohydrate ABC transporter permease [Rhizobium leguminosarum bv. viciae]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 12-277 5.49e-89

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 265.81  E-value: 5.49e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQ-GAFALPAYPHFENYVDAWNAGHFNIYFWNSIIVVIPVVAASVFLG 90
Cdd:COG0395    15 ILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSgPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  91 LLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQLPEEV 170
Cdd:COG0395    95 SLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQFFRSIPREL 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 171 LEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGMLFFQGRYTVNTPVLTAGAV 250
Cdd:COG0395   175 EEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAV 254

                         250       260
                  ....*....|....*....|....*..
gi 1586791995 251 IVIFPLIVTYLVFQRRFIAGLTAGATK 277
Cdd:COG0395   255 IATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 12-277 5.49e-89

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 265.81  E-value: 5.49e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQ-GAFALPAYPHFENYVDAWNAGHFNIYFWNSIIVVIPVVAASVFLG 90
Cdd:COG0395    15 ILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSgPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  91 LLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQLPEEV 170
Cdd:COG0395    95 SLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQFFRSIPREL 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 171 LEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGMLFFQGRYTVNTPVLTAGAV 250
Cdd:COG0395   175 EEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAV 254

                         250       260
                  ....*....|....*....|....*..
gi 1586791995 251 IVIFPLIVTYLVFQRRFIAGLTAGATK 277
Cdd:COG0395   255 IATLPVLILFLFLQRYFVRGLTAGAVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
12-271 2.72e-22

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 93.26  E-value: 2.72e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQGAFALPAYPH-FENYVDAW------NAGHFNIYFWNSIIVVIPVVA 84
Cdd:PRK10973   10 IFSHTMLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHlLENIANIWvngvgnNSAPFGRMLLNSFVMAFSITV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  85 ASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIpfSTIFLASAMQ 164
Cdd:PRK10973   90 GKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASAT--ATFLFRQFFM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 165 QLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLG---MLFFQGRYTVN 241
Cdd:PRK10973  168 TLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGikgMIATGEGTTEW 247

                         250       260       270
                  ....*....|....*....|....*....|
gi 1586791995 242 TPVLTAGAVIVIFPLIVTyLVFQRRFIAGL 271
Cdd:PRK10973  248 NQVMAAMLLTLIPPVVIV-LAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-257 9.39e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.07  E-value: 9.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  72 FWNSIIVVIPVVAASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVP----Q 147
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPalilA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 148 IAMSIPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTL 227
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1586791995 228 PLGMLFFQGRYTVNTPVLTAGAVIVIFPLI 257
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 86-263 1.29e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  86 SVFLGLLTGFafaYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQ 165
Cdd:pfam00528   1 GIPLGIIAAL---RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 166 LPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDayrtlPLGMLFFQGRYTVNTPVL 245
Cdd:pfam00528  78 LPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEI 152

                         170
                  ....*....|....*...
gi 1586791995 246 TAGAVIVIFPLIVTYLVF 263
Cdd:pfam00528 153 QGPVLAAALILLLLNLLV 170
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 12-277 5.49e-89

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 265.81  E-value: 5.49e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQ-GAFALPAYPHFENYVDAWNAGHFNIYFWNSIIVVIPVVAASVFLG 90
Cdd:COG0395    15 ILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSgPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  91 LLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQLPEEV 170
Cdd:COG0395    95 SLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLRQFFRSIPREL 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 171 LEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGMLFFQGRYTVNTPVLTAGAV 250
Cdd:COG0395   175 EEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAV 254

                         250       260
                  ....*....|....*....|....*..
gi 1586791995 251 IVIFPLIVTYLVFQRRFIAGLTAGATK 277
Cdd:COG0395   255 IATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 12-277 2.26e-52

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 172.26  E-value: 2.26e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIkSKADVLQGAFALPAYPHFENYVDAWNAGHFNIYFWNSIIVVIPVVAASVFLGL 91
Cdd:COG3833    16 GLRHLVLIILAIIALFPILWVVSASF-NPGGSLYSSSLIPENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  92 LTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQLPEEVL 171
Cdd:COG3833    95 LAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMKGYFDTIPKELD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 172 EAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGM-LFFQGRYTVNTPVLTAGAV 250
Cdd:COG3833   175 EAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLySFVSDQRNTNWGVFAAGAV 254

                         250       260
                  ....*....|....*....|....*..
gi 1586791995 251 IVIFPLIVTYLVFQRRFIAGLTAGATK 277
Cdd:COG3833   255 LVAIPIVILFLFLQRYLVSGLTAGGVK 281
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 10-265 4.57e-27

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 105.58  E-value: 4.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  10 GPLFLRIVLWLLAFVTIIPFLLLLLTSIKSKadvlQGAFALPAYPHFENYVDAWNAGHFNIYFWNSIIVVIPVVAASVFL 89
Cdd:COG1177     5 GRLLLRLFLALVLLFLYLPILVLVLYSFNDS----WFLTFPPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLATVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  90 GLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQLPEE 169
Cdd:COG1177    81 GTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 170 VLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDaYRTLPLGMlfFQGRYTVNTPVLTAGA 249
Cdd:COG1177   161 LEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPG-VTTLPVYI--YSMIRRGISPEINALS 237

                         250
                  ....*....|....*.
gi 1586791995 250 VIVIFPLIVTYLVFQR 265
Cdd:COG1177   238 TLLILLSLLLLLLAER 253
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
12-271 2.72e-22

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 93.26  E-value: 2.72e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  12 LFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQGAFALPAYPH-FENYVDAW------NAGHFNIYFWNSIIVVIPVVA 84
Cdd:PRK10973   10 IFSHTMLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHlLENIANIWvngvgnNSAPFGRMLLNSFVMAFSITV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  85 ASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIpfSTIFLASAMQ 164
Cdd:PRK10973   90 GKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASAT--ATFLFRQFFM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 165 QLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLG---MLFFQGRYTVN 241
Cdd:PRK10973  168 TLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGikgMIATGEGTTEW 247

                         250       260       270
                  ....*....|....*....|....*....|
gi 1586791995 242 TPVLTAGAVIVIFPLIVTyLVFQRRFIAGL 271
Cdd:PRK10973  248 NQVMAAMLLTLIPPVVIV-LAMQRAFVRGL 276
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
9-263 8.78e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 79.82  E-value: 8.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995   9 AGPLFLRIVLWLLAFVTIIPFLLLLLTSIkskADVLQGAFALPAYPHFENYVDAWNAghfniyFWNSIIVVIPVVAASVF 88
Cdd:COG1178   286 WRWLALALCLLLVLLGLLLPLLALLLWSL---TKALDDNLTLDNYRFVLLDPSLLRA------LLNSLLLALLAALLAVL 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  89 LGLLTGFAFAYLSFPLRRTLFAILTLGMMVP----AEAFIIPlYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQ 164
Cdd:COG1178   357 LALLLAYLVRRRRGRLARLLDRLAMLPYAVPgivlGLGLLLL-FNRPLPLLLYGTLAILVLAYVVRFLPFALRSLEAALA 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 165 QLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDaYRTLPLGMLFFQGRYTVNtPV 244
Cdd:COG1178   436 QIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPG-FETLAVLIYQLASSGRYG-EA 513

                         250
                  ....*....|....*....
gi 1586791995 245 LTAGAVIVIFPLIVTYLVF 263
Cdd:COG1178   514 AALALLLVLVSLLPVLLLE 532
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
56-266 1.47e-15

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 74.79  E-value: 1.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  56 FENYVDAWNAGhfniYFWNSIIVVIPVVAASVFLGLLTGFAFAYL---SFPLRRTLFAILTLGMMVP--AEAFIIPLYYE 130
Cdd:COG1175    62 LDNYARLFTDP----RFWNALGNTLLFTVVSVPLQLVLGLLLALLlnrKLRGRGFFRTLFFLPWVISpvVVALIWKWLFN 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 131 MRYlGLINT-------------------YAALIVPQIAMSIPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIP 191
Cdd:COG1175   138 PDY-GLLNAllgalglepinwlgdpslaLPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLP 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 192 LMVPAMSTLALFLFIWTWNEFLIPFILVN---DDAYRTLPLgMLFFQGRYTVNTPVLTAGAVI---VIFPLIVTYLVFQR 265
Cdd:COG1175   217 LLRPTILFVLVLSTIGALQVFDLVYVLTGggpGNSTTTLVL-YIYQTAFQQFDFGYASAIAVVlflIILVLTLLQLRLLR 295


                  .
gi 1586791995 266 R 266
Cdd:COG1175   296 R 296
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-267 3.63e-15

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 73.64  E-value: 3.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995   1 MSRSFNISAGPLFLRI--VLWLLAFVtIIPFLLLLLTSIKSKADVLQGAFALpaypHFENYVDAWNAGHFNIYFWNSIIV 78
Cdd:COG1176     1 MSAALRRRLRPLLLLLpaLLWLLLFF-VLPLLLLLVYSFTTRDPYGGVVPGF----TLENYARLFTDPLYLKVLLRTLWI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  79 VIPVVAASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVP----AEAFIIPLYYE------MRYLGLI-------NTYA 141
Cdd:COG1176    76 ALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSflvrTYAWIVLLGRNgllnslLLALGLIdeplrllYTEF 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 142 ALIVPQIAMSIPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVND 221
Cdd:COG1176   156 AVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGG 235

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1586791995 222 dayRTLPLGML-FFQGRYTVNTPVLTAGAVIVIFPLIVTYLVFQRRF 267
Cdd:COG1176   236 ---KVLMIGNLiYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLL 279
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-257 9.39e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.07  E-value: 9.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  72 FWNSIIVVIPVVAASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVP----Q 147
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPalilA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 148 IAMSIPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTL 227
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1586791995 228 PLGMLFFQGRYTVNTPVLTAGAVIVIFPLI 257
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
9-263 2.23e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 69.80  E-value: 2.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995   9 AGPLFLRIVLWLLAFVTIIPFLLLLLTSIKSKADVLQGAFALPAYPHfenyvdawnaghfniYFWNSIIVVIPVVAASVF 88
Cdd:COG1178     8 RPRLLLLLLALLLALLVLLPLLALLLRAFTDGLANFWALLSDPYLWR---------------ALGNTLLLALLVTLLSLL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  89 LGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINT---------------YAALIVPQIAMSIP 153
Cdd:COG1178    73 LGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTllralfgleppdiygLGGIILVLVLFNYP 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 154 FSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILvnDDAYRTLPLGMLf 233
Cdd:COG1178   153 YVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGYTTLTTAIY- 229

                         250       260       270
                  ....*....|....*....|....*....|
gi 1586791995 234 fqgRYTVNTPVLTAGAVIVIFPLIVTYLVF 263
Cdd:COG1178   230 ---QAWLGDFDLGAAAALALVLLLLVLLLL 256
malG PRK10998
maltose ABC transporter permease MalG;
18-277 4.78e-12

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 64.73  E-value: 4.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  18 LWLLAFVTIIPFLLLLLTSIKSKADVLQGAFALPAYPHFENYVDAWNAGHFN-------------IYFWNSIIVVIPVVA 84
Cdd:PRK10998   18 LLLLGFIALIMFPLLMVIAISLREGNFATGSLIPEQISWEHWKLALGFSVEHadgrvtpppfpvlLWLWNSVKVAGITAI 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  85 ASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGL------INTYAALIVPQIA-MSIPFSTI 157
Cdd:PRK10998   98 GIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQyipfigLNTHGGVIFAYLGgIALHVWTI 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 158 flASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGMLFFQGR 237
Cdd:PRK10998  178 --KGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNP 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1586791995 238 YTVNTPVLTAGAVIVIFPLIVTYLVFQRRFIAGLTAGATK 277
Cdd:PRK10998  256 QNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 86-263 1.29e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  86 SVFLGLLTGFafaYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFSTIFLASAMQQ 165
Cdd:pfam00528   1 GIPLGIIAAL---RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 166 LPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDayrtlPLGMLFFQGRYTVNTPVL 245
Cdd:pfam00528  78 LPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEI 152

                         170
                  ....*....|....*...
gi 1586791995 246 TAGAVIVIFPLIVTYLVF 263
Cdd:pfam00528 153 QGPVLAAALILLLLNLLV 170
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 1-199 1.44e-08

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 54.37  E-value: 1.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995   1 MSRSFNISAGPLFLRIVLWLLAFVtIIPFLLLLLTSIKSKADVLQGAFALPayphfenyvDAWNAghfniyFWNSIIVVI 80
Cdd:COG0555     1 MSRRVLPGFGLTLGLTLLYLSLIV-LLPLAALVLKAAGLGWAEFWAVLTSP---------RVLAA------LKLSLGTAL 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  81 PVVAASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVP------------AEAFIIPLYYEMRYLGLINTYAALIVPQI 148
Cdd:COG0555    65 IAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPtavagiallllfGPNGWLGQLLAPLGIKVAFTPLGIVLAQT 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1586791995 149 AMSIPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMST 199
Cdd:COG0555   145 FVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLT 195
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 72-229 2.07e-08

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 53.83  E-value: 2.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  72 FWNSIIVVIPVVAASVFLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMRYLGLINTYAALIVPQIAMS 151
Cdd:PRK09500   59 AQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAHITFC 138

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1586791995 152 IPFSTIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFiLVNDDAYRTLPL 229
Cdd:PRK09500  139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDDVVVSS-FVTGPSYEILPL 215
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 16-195 1.54e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 39.29  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  16 IVLWLLAFVtIIPFLLLLLTSIKSKADVLQGAFALPayphFENYVDAWNAGHFNIyFWNSIIVVIpvvaASVFLGLLTGF 95
Cdd:PRK09497   15 IVGWLVLFV-FLPNLMIIGTSFLTRDDANFVKMVFT----LDNYTRLLDPLYAEV-LLHSLNMAL----IATLACLVLGY 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  96 AFAYLSFPLRRTLFAILTLGMMVPAEAFIIPLYYEMR--------------YLGLI-------NTYAALIVPQIAMSIPF 154
Cdd:PRK09497   85 PFAWFLAKLPHKVRPLLLFLLIVPFWTNSLIRIYGLKiflstkgylnefllWLGVIdtpirimFTESAVIIGLVYILLPF 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1586791995 155 STIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVP 195
Cdd:PRK09497  165 MVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMP 205
cysT CHL00187
sulfate transport protein; Provisional
 88-235 6.69e-03

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 37.30  E-value: 6.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995  88 FLGLLTGFAFAYLSFPLRRTLFAILTLGMMVPA------------EAFIIPLYYEMRYLGLINTYAALIVPQIAMSIPFS 155
Cdd:CHL00187   73 FFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTsvagltlatvygDNGWIGHLLSHLGIQIVFTKLGVLLAMIFVSFPFV 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586791995 156 TIFLASAMQQLPEEVLEAAVLDGAGRFYILRKIVIPLMVPAMSTLALFLFIWTWNEFLIPFILVNDDAYRTLPLGMLFFQ 235
Cdd:CHL00187  153 VRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVIISSNIPFKDLVASVLIFQ 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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