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Conserved domains on  [gi|1462672100|emb|SWO63547|]
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Rtn protein [Klebsiella pneumoniae]

Protein Classification

EAL domain-containing protein( domain architecture ID 13298220)

EAL domain-containing protein with a CSS motif may act as a cyclic diguanylate phosphodiesterase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjcC super family cl34845
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-492 4.75e-106

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG4943:

Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 326.49  E-value: 4.75e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100   1 MKEIKRRNAWIAFSL----ALVVFLAGVFVINWQLWHSDQATHVAAARQAAKKIAAILDEAREATATALNVSRSGCSGQG 76
Cdd:COG4943     1 MRMRRRRLLSLATLLallaALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  77 QFQLGTEAALQPHLRTILLIKDGQVWCSSLpGNRV--LTLSPESLPDEPLLLLPARMM---VNKRPVLIYQ--------A 143
Cdd:COG4943    81 LAALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSkpVPLPPPDYVTADGYRLWLNVDnplDPGRPMLIVGrgnyvvviD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 144 RVAAIRVIVTISDIHLrdALYSDTDN------NGLALWVQNQMIARYGDVKPLAaDPHQGVFTSPAYPFRITypdsLFFS 217
Cdd:COG4943   160 PAAFIDVLSPQPGISL--ALLATNGGhlfassGNPDPALLSRLLRGPSSWFIQG-DRLYASACSPQYPICVV----AAAP 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 218 PGRLVHNGSGLLIFIFS----VSLLFYFLMRKYLNVYTSEEERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNS 293
Cdd:COG4943   233 LAGLLALWRQLLLLLLPlgllLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDP 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 294 TTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSKLPDgFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKL 373
Cdd:COG4943   313 DGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAADPD-FHISINLSASDLLSPRFLDDLERLLARTGVAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 374 MLEITEQEPLLLNgVVVDKLNTLHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMA 453
Cdd:COG4943   392 VLEITERGFIDPA-KARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMA 470

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1462672100 454 RTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:COG4943   471 KTLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLP 509
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-492 4.75e-106

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 326.49  E-value: 4.75e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100   1 MKEIKRRNAWIAFSL----ALVVFLAGVFVINWQLWHSDQATHVAAARQAAKKIAAILDEAREATATALNVSRSGCSGQG 76
Cdd:COG4943     1 MRMRRRRLLSLATLLallaALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  77 QFQLGTEAALQPHLRTILLIKDGQVWCSSLpGNRV--LTLSPESLPDEPLLLLPARMM---VNKRPVLIYQ--------A 143
Cdd:COG4943    81 LAALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSkpVPLPPPDYVTADGYRLWLNVDnplDPGRPMLIVGrgnyvvviD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 144 RVAAIRVIVTISDIHLrdALYSDTDN------NGLALWVQNQMIARYGDVKPLAaDPHQGVFTSPAYPFRITypdsLFFS 217
Cdd:COG4943   160 PAAFIDVLSPQPGISL--ALLATNGGhlfassGNPDPALLSRLLRGPSSWFIQG-DRLYASACSPQYPICVV----AAAP 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 218 PGRLVHNGSGLLIFIFS----VSLLFYFLMRKYLNVYTSEEERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNS 293
Cdd:COG4943   233 LAGLLALWRQLLLLLLPlgllLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDP 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 294 TTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSKLPDgFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKL 373
Cdd:COG4943   313 DGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAADPD-FHISINLSASDLLSPRFLDDLERLLARTGVAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 374 MLEITEQEPLLLNgVVVDKLNTLHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMA 453
Cdd:COG4943   392 VLEITERGFIDPA-KARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMA 470

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1462672100 454 RTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:COG4943   471 KTLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLP 509
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 255-492 1.24e-83

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 259.01  E-value: 1.24e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 255 ERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSK 334
Cdd:cd01948     1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 335 LPDgFHIGLNISASHINAPTFIDDCLHF--QHGFEgkAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTGY 412
Cdd:cd01948    81 GPD-LRLSVNLSARQLRDPDFLDRLLELlaETGLP--PRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGY 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 413 SGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:cd01948   158 SSLSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLP 237
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 254-492 3.28e-83

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 257.92  E-value: 3.28e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFS 333
Cdd:smart00052   1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  334 KLPDGFHIGLNISASHINAPTFIDDCLHF--QHGFEgkAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTG 411
Cdd:smart00052  81 QGPPPLLISINLSARQLISPDLVPRVLELleETGLP--PQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  412 YSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPM 491
Cdd:smart00052 159 YSSLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPL 238


                   .
gi 1462672100  492 P 492
Cdd:smart00052 239 P 239
PRK10551 PRK10551
cyclic di-GMP phosphodiesterase;
6-497 2.18e-74

cyclic di-GMP phosphodiesterase;


Pssm-ID: 182541 [Multi-domain]  Cd Length: 518  Bit Score: 244.13  E-value: 2.18e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100   6 RRNAWIAFSLALVVF-LAGVFVINWqLWHSDQATHVAAARQAAKKIAAILDEAREATATALNVSRSGCSgQGQFQLGTEA 84
Cdd:PRK10551   10 RKILLTSIVAGVMIAlLFSCLQFLL-LWHKREVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQ-QVNPELTSRA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  85 ALQPHLRTILLIKDGQVWCSSLPGNR---VLTLSPE---SLPDEPLLLLPARMMVNKrPVLIYQARVAAI--RVIVTISD 156
Cdd:PRK10551   88 AFSLNVRAFLLVKDKKAFCSSATGEMntpLSELIPAidiNKPVDMAILPGTPMMPNK-PAIVIWYRNPLLknSGVFATLN 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 157 IHLRDAL---YSDTDNNGLALWVQNQMI----ARYGDVKPLAADPHQGVfTSPAYPFRIT-YPDSLFFSPGRLVHNGSGL 228
Cdd:PRK10551  167 LNLTPYLlytSRQEDFDGIALIIGNTALstfsSRLMNVNELPDMPLRET-TIPGYPLTIRlYADSWTANDIWYALLLGLL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 229 LIFIfsVSLLFYFLMRKYLNvytSEEERLRyAINQG--YIVpyYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPL 306
Cdd:PRK10551  246 SGIL--VGLLCYYLLSLRMR---PGKEILT-GIKRGqfYVE--YQPVVDTQTLRVTGLEALLRWRHPTAGEIPPDAFINY 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 307 AERTGLIIPLTRSLMAQVnAQMRPLFSK-LPDGFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKLMLEITEQEplll 385
Cdd:PRK10551  318 AEAQKLIVPLTQHLFELI-ARDAAELQKvLPVGAKLGINISPAHLHSDSFKADVQRLLASLPADHFQIVLEITERD---- 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 386 ngvVVDKLNT------LHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLR 459
Cdd:PRK10551  393 ---MVQEEEAtklfawLHSQGIEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVLTLAKRLNML 469

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1462672100 460 IIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMPYVALV 497
Cdd:PRK10551  470 TVAEGVETPEQARWLRERGVNFLQGYWISRPLPLEDFV 507
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 254-490 7.48e-63

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 204.86  E-value: 7.48e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLfs 333
Cdd:pfam00563   1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQL-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 334 KLPDGFHIGLNISASHINAPTFIDDCLHF-QHGFEGKAvKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTGY 412
Cdd:pfam00563  79 QLGPDIKLSINLSPASLADPGFLELLRALlKQAGPPPS-RLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGY 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462672100 413 SGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKP 490
Cdd:pfam00563 158 SSLSYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
 
Name Accession Description Interval E-value
YjcC COG4943
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ...
 1-492 4.75e-106

Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];


Pssm-ID: 443970 [Multi-domain]  Cd Length: 528  Bit Score: 326.49  E-value: 4.75e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100   1 MKEIKRRNAWIAFSL----ALVVFLAGVFVINWQLWHSDQATHVAAARQAAKKIAAILDEAREATATALNVSRSGCSGQG 76
Cdd:COG4943     1 MRMRRRRLLSLATLLallaALLPLLLSLWLAQIQARRREREQLESYAQRALARAERVFDQARSALDELNALPGDPCSPAH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  77 QFQLGTEAALQPHLRTILLIKDGQVWCSSLpGNRV--LTLSPESLPDEPLLLLPARMM---VNKRPVLIYQ--------A 143
Cdd:COG4943    81 LAALRRLVFSSRYVRDIGYVRDGRLLCSSL-GKLSkpVPLPPPDYVTADGYRLWLNVDnplDPGRPMLIVGrgnyvvviD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 144 RVAAIRVIVTISDIHLrdALYSDTDN------NGLALWVQNQMIARYGDVKPLAaDPHQGVFTSPAYPFRITypdsLFFS 217
Cdd:COG4943   160 PAAFIDVLSPQPGISL--ALLATNGGhlfassGNPDPALLSRLLRGPSSWFIQG-DRLYASACSPQYPICVV----AAAP 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 218 PGRLVHNGSGLLIFIFS----VSLLFYFLMRKYLNVYTSEEERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNS 293
Cdd:COG4943   233 LAGLLALWRQLLLLLLPlgllLSLLLGLLVLRLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDP 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 294 TTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSKLPDgFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKL 373
Cdd:COG4943   313 DGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLGDLLAADPD-FHISINLSASDLLSPRFLDDLERLLARTGVAPQQI 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 374 MLEITEQEPLLLNgVVVDKLNTLHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMA 453
Cdd:COG4943   392 VLEITERGFIDPA-KARAVIAALREAGHRIAIDDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMA 470

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1462672100 454 RTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:COG4943   471 KTLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAKPLP 509
EAL cd01948
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 255-492 1.24e-83

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.


Pssm-ID: 238923 [Multi-domain]  Cd Length: 240  Bit Score: 259.01  E-value: 1.24e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 255 ERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSK 334
Cdd:cd01948     1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 335 LPDgFHIGLNISASHINAPTFIDDCLHF--QHGFEgkAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTGY 412
Cdd:cd01948    81 GPD-LRLSVNLSARQLRDPDFLDRLLELlaETGLP--PRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGY 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 413 SGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:cd01948   158 SSLSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLP 237
EAL smart00052
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ...
 254-492 3.28e-83

Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.


Pssm-ID: 214491 [Multi-domain]  Cd Length: 242  Bit Score: 257.92  E-value: 3.28e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFS 333
Cdd:smart00052   1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  334 KLPDGFHIGLNISASHINAPTFIDDCLHF--QHGFEgkAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTG 411
Cdd:smart00052  81 QGPPPLLISINLSARQLISPDLVPRVLELleETGLP--PQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  412 YSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPM 491
Cdd:smart00052 159 YSSLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPL 238


                   .
gi 1462672100  492 P 492
Cdd:smart00052 239 P 239
COG5001 COG5001
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ...
 254-504 2.03e-77

Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];


Pssm-ID: 444025 [Multi-domain]  Cd Length: 678  Bit Score: 256.24  E-value: 2.03e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNsttPSR---SPAEFIPLAERTGLIIPLTRSLMAQVNAQMRP 330
Cdd:COG5001   427 EADLRRALERGELELHYQPQVDLATGRIVGAEALLRWQH---PERglvSPAEFIPLAEETGLIVPLGEWVLREACRQLAA 503

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 331 LFSKLPDGFHIGLNISASHINAPTFID---DCLHfQHGFEGKAvkLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDD 407
Cdd:COG5001   504 WQDAGLPDLRVAVNLSARQLRDPDLVDrvrRALA-ETGLPPSR--LELEITESALLEDPEEALETLRALRALGVRIALDD 580

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 408 FGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYF 487
Cdd:COG5001   581 FGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVETEEQLEFLRELGCDYAQGYLF 660

                         250
                  ....*....|....*..
gi 1462672100 488 WKPMPYVALVMLLLSKP 504
Cdd:COG5001   661 SRPLPAEELEALLRARA 677
PRK10551 PRK10551
cyclic di-GMP phosphodiesterase;
6-497 2.18e-74

cyclic di-GMP phosphodiesterase;


Pssm-ID: 182541 [Multi-domain]  Cd Length: 518  Bit Score: 244.13  E-value: 2.18e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100   6 RRNAWIAFSLALVVF-LAGVFVINWqLWHSDQATHVAAARQAAKKIAAILDEAREATATALNVSRSGCSgQGQFQLGTEA 84
Cdd:PRK10551   10 RKILLTSIVAGVMIAlLFSCLQFLL-LWHKREVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQ-QVNPELTSRA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  85 ALQPHLRTILLIKDGQVWCSSLPGNR---VLTLSPE---SLPDEPLLLLPARMMVNKrPVLIYQARVAAI--RVIVTISD 156
Cdd:PRK10551   88 AFSLNVRAFLLVKDKKAFCSSATGEMntpLSELIPAidiNKPVDMAILPGTPMMPNK-PAIVIWYRNPLLknSGVFATLN 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 157 IHLRDAL---YSDTDNNGLALWVQNQMI----ARYGDVKPLAADPHQGVfTSPAYPFRIT-YPDSLFFSPGRLVHNGSGL 228
Cdd:PRK10551  167 LNLTPYLlytSRQEDFDGIALIIGNTALstfsSRLMNVNELPDMPLRET-TIPGYPLTIRlYADSWTANDIWYALLLGLL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 229 LIFIfsVSLLFYFLMRKYLNvytSEEERLRyAINQG--YIVpyYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPL 306
Cdd:PRK10551  246 SGIL--VGLLCYYLLSLRMR---PGKEILT-GIKRGqfYVE--YQPVVDTQTLRVTGLEALLRWRHPTAGEIPPDAFINY 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 307 AERTGLIIPLTRSLMAQVnAQMRPLFSK-LPDGFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKLMLEITEQEplll 385
Cdd:PRK10551  318 AEAQKLIVPLTQHLFELI-ARDAAELQKvLPVGAKLGINISPAHLHSDSFKADVQRLLASLPADHFQIVLEITERD---- 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 386 ngvVVDKLNT------LHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLR 459
Cdd:PRK10551  393 ---MVQEEEAtklfawLHSQGIEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVLTLAKRLNML 469

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1462672100 460 IIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMPYVALV 497
Cdd:PRK10551  470 TVAEGVETPEQARWLRERGVNFLQGYWISRPLPLEDFV 507
EAL COG2200
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ...
 254-500 7.42e-74

EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];


Pssm-ID: 441802 [Multi-domain]  Cd Length: 576  Bit Score: 244.31  E-value: 7.42e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFS 333
Cdd:COG2200   330 ESELREALEEGELRLYYQPIVDLRTGRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERALRQLARWPE 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 334 KLPDgFHIGLNISASHINAPTFIDDCLHF--QHGFEGKavKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTG 411
Cdd:COG2200   410 RGLD-LRLSVNLSARSLLDPDFLERLLELlaEYGLPPE--RLVLEITESALLEDLEAAIELLARLRALGVRIALDDFGTG 486

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 412 YSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPM 491
Cdd:COG2200   487 YSSLSYLKRLPPDYLKIDRSFVRDIARDPRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALRELGCDYAQGYLFGRPL 566


                  ....*....
gi 1462672100 492 PYVALVMLL 500
Cdd:COG2200   567 PLEELEALL 575
EAL pfam00563
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ...
 254-490 7.48e-63

EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.


Pssm-ID: 425752 [Multi-domain]  Cd Length: 235  Bit Score: 204.86  E-value: 7.48e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 254 EERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLfs 333
Cdd:pfam00563   1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQL-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 334 KLPDGFHIGLNISASHINAPTFIDDCLHF-QHGFEGKAvKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGTGY 412
Cdd:pfam00563  79 QLGPDIKLSINLSPASLADPGFLELLRALlKQAGPPPS-RLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGY 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462672100 413 SGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKP 490
Cdd:pfam00563 158 SSLSYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
PRK10060 PRK10060
cyclic di-GMP phosphodiesterase;
257-509 2.29e-41

cyclic di-GMP phosphodiesterase;


Pssm-ID: 236645 [Multi-domain]  Cd Length: 663  Bit Score: 157.54  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 257 LRYAINQGYIVPYYQPLVNGkTGEIYGVEILARWQnstTPSR---SPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFS 333
Cdd:PRK10060  413 LRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQ---SPERgliPPLEFISYAEESGLIVPLGRWVMLDVVRQVAKWRD 488

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 334 KlPDGFHIGLNISASHINAPTFIDDCLHFQHGFEGKAVKLMLEITEQ-----EPLLLNgvVVDKLNTLhnrGFSIALDDF 408
Cdd:PRK10060  489 K-GINLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTESclienEELALS--VIQQFSQL---GAQVHLDDF 562

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 409 GTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFW 488
Cdd:PRK10060  563 GTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFA 642

                         250       260
                  ....*....|....*....|.
gi 1462672100 489 KPMPYVALVMLLLSKPKARII 509
Cdd:PRK10060  643 KPMPAVAFERWYKRYLKRKLI 663
PRK11359 PRK11359
cyclic-di-GMP phosphodiesterase; Provisional
 257-492 8.94e-41

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183097 [Multi-domain]  Cd Length: 799  Bit Score: 156.85  E-value: 8.94e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 257 LRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQM---RPLFS 333
Cdd:PRK11359  548 LKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLaewRSQNI 627

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 334 KLPDgfhIGLNISASHINA---PTFIDDCLHfQHGFEGKavKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIALDDFGT 410
Cdd:PRK11359  628 HIPA---LSVNLSALHFRSnqlPNQVSDAMQ-AWGIDGH--QLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGT 701

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 411 GYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKP 490
Cdd:PRK11359  702 GFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRP 781


                  ..
gi 1462672100 491 MP 492
Cdd:PRK11359  782 LP 783
PRK11829 PRK11829
biofilm formation regulator HmsP; Provisional
 252-492 1.86e-34

biofilm formation regulator HmsP; Provisional


Pssm-ID: 183329 [Multi-domain]  Cd Length: 660  Bit Score: 137.38  E-value: 1.86e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 252 SEEERLRYAINQGYIVPYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQ-----VNA 326
Cdd:PRK11829  405 TQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMVPLGNWVLEEacrilADW 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 327 QMRPLfsKLPdgfhIGLNISASHINAPTFID--DCLHFQHGFEgkAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIA 404
Cdd:PRK11829  485 KARGV--SLP----LSVNISGLQVQNKQFLPhlKTLISHYHID--PQQLLLEITETAQIQDLDEALRLLRELQGLGLLIA 556

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 405 LDDFGTGYSGLSYLH---ELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMartLSLRIIAEGVETQAQLEYLNRQNIHL 481
Cdd:PRK11829  557 LDDFGIGYSSLRYLNhlkSLPIHMIKLDKSFVKNLPEDDAIARIISCVSDV---LKVRVMAEGVETEEQRQWLLEHGIQC 633

                         250
                  ....*....|.
gi 1462672100 482 LQGYYFWKPMP 492
Cdd:PRK11829  634 GQGFLFSPPLP 644
PRK13561 PRK13561
putative diguanylate cyclase; Provisional
 255-492 6.80e-34

putative diguanylate cyclase; Provisional


Pssm-ID: 184143 [Multi-domain]  Cd Length: 651  Bit Score: 135.61  E-value: 6.80e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 255 ERLRYAInqgyivpYYQPLVNGKTGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPL--------TRSLMA-QVN 325
Cdd:PRK13561  410 ENHQFAI-------WLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPEGLIDRIESCGLMVTVghwvleesCRLLAAwQER 482

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 326 AQMRPLfsklpdgfhiGLNISASHINAPTFIDDCLHFQHGFEGKAVKLMLEITEQEPLLLNGVVVDKLNTLHNRGFSIAL 405
Cdd:PRK13561  483 GIMLPL----------SVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVAL 552

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 406 DDFGTGYSGLSYLHE---LVFDYIKIDQSFVArvtGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLL 482
Cdd:PRK13561  553 DDFGMGYAGLRQLQHmksLPIDVLKIDKMFVD---GLPEDDSMVAAIIMLAQSLNLQVIAEGVETEAQRDWLLKAGVGIA 629

                         250
                  ....*....|
gi 1462672100 483 QGYYFWKPMP 492
Cdd:PRK13561  630 QGFLFARALP 639
PRK09776 PRK09776
putative diguanylate cyclase; Provisional
 284-497 1.29e-17

putative diguanylate cyclase; Provisional


Pssm-ID: 182070 [Multi-domain]  Cd Length: 1092  Bit Score: 86.26  E-value: 1.29e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  284 VEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVNAQMRPLFSKlpDGFHIGLNISASHINAPTFIDD-CLHF 362
Cdd:PRK09776   873 WLISLRLWDPEGEIIDEGAFRPAAEDPALMHALDRRVIHEFFRQAAKAVAS--KGLSIALPLSVAGLSSPTLLPFlLEQL 950

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  363 QHGFEGkAVKLMLEITEqEPLLLNGVVVDK-LNTLHNRGFSIALDDFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAP 441
Cdd:PRK09776   951 ENSPLP-PRLLHLEITE-TALLNHAESASRlVQKLRLAGCRVVLSDFGRGLSSFNYLKAFMADYLKLDGELVANLHGNLM 1028

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1462672100  442 SSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMPYVALV 497
Cdd:PRK09776  1029 DEMLISIIQGHAQRLGMKTIAGPVELPLVLDTLSGIGVDLAYGYAIARPQPLDLLL 1084
CSS-motif pfam12792
CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS ...
 41-208 6.53e-15

CSS motif domain associated with EAL; This family with its characteriztic highly conserved CSS sequence motif is found N-terminal to the EAL, pfam00563, domain in many cyclic diguanylate phosphodiesterases.


Pssm-ID: 463709  Cd Length: 209  Bit Score: 73.71  E-value: 6.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100  41 AAARQAAKKIAAILDEAREATATALNVSRSGCSGQGQFQLGTEAALQPHLRTILLIKDGQVWCSSLPGNRVLTLS----- 115
Cdd:pfam12792   7 AFAERALRRLESVLDQADQALDRLLPLTGQPCSPAHLAELRRIVAFSPYVRDVGLVKNGRLYCSSLWGELDTPLPllppd 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 116 PESLPDEPLLLLPARMMVNKRPVLIYQARVAA--IRVIVTISDIHLRDALY--SDTDNNGLALWVQNQMIARYGDVKPLA 191
Cdd:pfam12792  87 LTTPPGVRLWLLRGTPLVPGRPALVLRRGGYGvvIDPGVFIDVQYLPGLLAavSQPDGRLLALVVGDDALLFDGRLHSLA 166

                         170       180
                  ....*....|....*....|....*.
gi 1462672100 192 ADPHQG---------VFTSPAYPFRI 208
Cdd:pfam12792 167 EPAPGTarsggalyaRARSTRYPLTV 192
YuxH COG3434
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ...
 372-492 4.88e-14

c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];


Pssm-ID: 442660 [Multi-domain]  Cd Length: 407  Bit Score: 73.68  E-value: 4.88e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 372 KLMLEITEQEPLllNGVVVDKLNTLHNRGFSIALDDFgtgySGLSYLHELV--FDYIKIDqsfVARVTGEApssklLDCV 449
Cdd:COG3434    85 RVVLEILEDVEP--DEELLEALKELKEKGYRIALDDF----VLDPEWDPLLplADIIKID---VLALDLEE-----LAEL 150

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1462672100 450 IEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYYFWKPMP 492
Cdd:COG3434   151 VARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEI 193
PRK11596 PRK11596
cyclic-di-GMP phosphodiesterase; Provisional
 405-493 4.21e-09

cyclic-di-GMP phosphodiesterase; Provisional


Pssm-ID: 183222 [Multi-domain]  Cd Length: 255  Bit Score: 57.32  E-value: 4.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 405 LDDFGTGYSGLSYLHELVFDYIKIDQS-FVA-RVTGEApsSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLL 482
Cdd:PRK11596  157 LDDFGTGMANFSALSEVRYDYIKVARElFIMlRQSEEG--RNLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAA 234

                          90
                  ....*....|.
gi 1462672100 483 QGYYFWKPMPY 493
Cdd:PRK11596  235 QGYFLSRPAPF 245
PRK11059 PRK11059
regulatory protein CsrD; Provisional
 257-494 1.79e-05

regulatory protein CsrD; Provisional


Pssm-ID: 236833 [Multi-domain]  Cd Length: 640  Bit Score: 47.55  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 257 LRYAINQGYIVPYYQPLVNGKtGEIYGVEILARWQNSTTPSRSPAEFIPLAERTGLIIPLTRSLMAQVnaqmRPLFSKLP 336
Cdd:PRK11059  408 LEQTLVRGGPRLYQQPAVTRD-GKVHHRELFCRIRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERV----LPLLRYWP 482

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 337 DGfHIGLNISASHINAPTFI----DDCLhfQHGFEgKAVKLMLEITE------QEPLllngvvVDKLNTLHNRGFSIALD 406
Cdd:PRK11059  483 EE-NLSINLSVDSLLSRAFQrwlrDTLL--QCPRS-QRKRLIFELAEadvcqhISRL------RPVLRMLRGLGCRLAVD 552

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462672100 407 DFGTGYSGLSYLHELVFDYIKIDQSFVARVTGEAPSSKLLDCVIEMARTLSLRIIAEGVETQAQLEYLNRQNIHLLQGYY 486
Cdd:PRK11059  553 QAGLTVVSTSYIKELNVELIKLHPSLVRNIHKRTENQLFVRSLVGACAGTETQVFATGVESREEWQTLQELGVSGGQGDF 632


                  ....*...
gi 1462672100 487 FWKPMPYV 494
Cdd:PRK11059  633 FAESQPLD 640
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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