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Conserved domains on  [gi|1443382284|emb|SUY58279|]
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single-strand binding protein [Clostridium tetani]

Protein Classification

single-stranded DNA-binding protein( domain architecture ID 11427956)

single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair

CATH:  2.40.50.140
Gene Ontology:  GO:0003697|GO:0006260
PubMed:  12598368|8458342|27838363
SCOP:  4000346

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
1-112 4.31e-49

Single-stranded DNA-binding protein [Replication, recombination and repair];


:

Pssm-ID: 440394  Cd Length: 116  Bit Score: 153.07  E-value: 4.31e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSKDG---KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQ 77
Cdd:COG0629     1 MNKVTLVGRLGKDPELRYTPS-GTAVANFRLAVNRRYKDQDgewKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLR 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1443382284  78 TRSYEAKDGTRRYVTEVVADEVKFLEWGNKQSSGS 112
Cdd:COG0629    80 TRSWEDKDGQKRYTTEVVADEIQFLGSRPSGGGGG 114
 
Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
1-112 4.31e-49

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 153.07  E-value: 4.31e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSKDG---KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQ 77
Cdd:COG0629     1 MNKVTLVGRLGKDPELRYTPS-GTAVANFRLAVNRRYKDQDgewKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLR 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1443382284  78 TRSYEAKDGTRRYVTEVVADEVKFLEWGNKQSSGS 112
Cdd:COG0629    80 TRSWEDKDGQKRYTTEVVADEIQFLGSRPSGGGGG 114
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 1-102 2.21e-44

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 140.83  E-value: 2.21e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKDG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQT 78
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTP-NGNAVANFTLATNRRFKDRGegDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQT 79

                          90       100
                  ....*....|....*....|....
gi 1443382284  79 RSYEAKDGTRRYVTEVVADEVKFL 102
Cdd:pfam00436  80 RKYEDQEGQKRYVTEIVADEVQFL 103
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 1-122 3.91e-43

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 139.64  E-value: 3.91e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF-SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTR 79
Cdd:PRK07275    2 INNVVLVGRMTRDAELRYTP-SNVAVATFTLAVNRTFkSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1443382284  80 SYEAKDGTRRYVTEVVADEVKFLEW-----GNKQSSGSQGFNNFESDP 122
Cdd:PRK07275   81 NYENQQGQRVYVTEVVADNFQMLESratreGGSGGSYNGGFNNAPSAN 128
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 2-145 6.88e-43

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 139.09  E-value: 6.88e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   2 NRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSK---DGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQT 78
Cdd:TIGR00621   5 NKVILVGRLTRDPELRYTPS-GNAVANFTLATNRRWKDqdgEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLRT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284  79 RSYEAKDGTRRYVTEVVADEVKFLEW-------GNKQSSGSQGFNNFESDPLSYNNEDNYN-----DDITPVD--EGEVP 144
Cdd:TIGR00621  84 RKWEDQNGQKRSKTEIIADNVQLLDLlgaraqgGEFSGGGGSGNRPQGGQEQSATGKDPAQsapqsGSADPIDgdDDEIP 163


                  .
gi 1443382284 145 F 145
Cdd:TIGR00621 164 F 164
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 4-102 7.78e-40

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 129.27  E-value: 7.78e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   4 VVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSKDG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTRSY 81
Cdd:cd04496     1 VILIGRLGKDPELRYTPS-GTPVARFSLAVNRRRKDRDeeEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSW 79

                          90       100
                  ....*....|....*....|.
gi 1443382284  82 EAKDGTRRYVTEVVADEVKFL 102
Cdd:cd04496    80 EDKDGQKRYGTEVVADRIEFL 100
 
Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
1-112 4.31e-49

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 153.07  E-value: 4.31e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSKDG---KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQ 77
Cdd:COG0629     1 MNKVTLVGRLGKDPELRYTPS-GTAVANFRLAVNRRYKDQDgewKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLR 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1443382284  78 TRSYEAKDGTRRYVTEVVADEVKFLEWGNKQSSGS 112
Cdd:COG0629    80 TRSWEDKDGQKRYTTEVVADEIQFLGSRPSGGGGG 114
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 1-102 2.21e-44

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 140.83  E-value: 2.21e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKDG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQT 78
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTP-NGNAVANFTLATNRRFKDRGegDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQT 79

                          90       100
                  ....*....|....*....|....
gi 1443382284  79 RSYEAKDGTRRYVTEVVADEVKFL 102
Cdd:pfam00436  80 RKYEDQEGQKRYVTEIVADEVQFL 103
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 1-122 3.91e-43

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 139.64  E-value: 3.91e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF-SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTR 79
Cdd:PRK07275    2 INNVVLVGRMTRDAELRYTP-SNVAVATFTLAVNRTFkSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1443382284  80 SYEAKDGTRRYVTEVVADEVKFLEW-----GNKQSSGSQGFNNFESDP 122
Cdd:PRK07275   81 NYENQQGQRVYVTEVVADNFQMLESratreGGSGGSYNGGFNNAPSAN 128
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 2-145 6.88e-43

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 139.09  E-value: 6.88e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   2 NRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSK---DGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQT 78
Cdd:TIGR00621   5 NKVILVGRLTRDPELRYTPS-GNAVANFTLATNRRWKDqdgEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLRT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284  79 RSYEAKDGTRRYVTEVVADEVKFLEW-------GNKQSSGSQGFNNFESDPLSYNNEDNYN-----DDITPVD--EGEVP 144
Cdd:TIGR00621  84 RKWEDQNGQKRSKTEIIADNVQLLDLlgaraqgGEFSGGGGSGNRPQGGQEQSATGKDPAQsapqsGSADPIDgdDDEIP 163


                  .
gi 1443382284 145 F 145
Cdd:TIGR00621 164 F 164
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 1-145 5.11e-41

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 134.93  E-value: 5.11e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFS-KDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTR 79
Cdd:PRK06751    2 MNRVILVGRLTKDPDLRYTP-NGVAVATFTLAVNRAFAnQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1443382284  80 SYEAKDGTRRYVTEVVADEVKFLE----------WGNKQSSGSqGFNNFESDPL--SYNNEDNYNDDITPVDEGEVPF 145
Cdd:PRK06751   81 NYEGQDGKRVYVTEVLAESVQFLEprngggeqrgSFNQQPSGA-GFGNQSSNPFgqSSNSGNQGNQGNSGFTKNDDPF 157
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 4-102 7.78e-40

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 129.27  E-value: 7.78e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   4 VVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSKDG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTRSY 81
Cdd:cd04496     1 VILIGRLGKDPELRYTPS-GTPVARFSLAVNRRRKDRDeeEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSW 79

                          90       100
                  ....*....|....*....|.
gi 1443382284  82 EAKDGTRRYVTEVVADEVKFL 102
Cdd:cd04496    80 EDKDGQKRYGTEVVADRIEFL 100
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 1-111 9.36e-34

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 114.36  E-value: 9.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKD-GKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTR 79
Cdd:PRK06752    2 MNRVVLIGRLTKEPELYYTK-QGVAYARVCVAVNRGFRNSlGEQQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIHTR 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1443382284  80 SYEAKDGTRRYVTEVVADEVKFLEWGNKQSSG 111
Cdd:PRK06752   81 NYEDDQGKRIYITEVVIESITFLERRREGASQ 112
PRK07274 PRK07274
single-stranded DNA-binding protein; Provisional
 1-103 4.51e-33

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180914  Cd Length: 131  Bit Score: 113.31  E-value: 4.51e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF-SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTR 79
Cdd:PRK07274    2 YNKVILIGRLTATPELVKTA-NDKSVARVTLAVNRRFkNQNGEREADFINVVLWGKLAETLASYASKGSLISIDGELRTR 80

                          90       100
                  ....*....|....*....|....
gi 1443382284  80 SYEaKDGTRRYVTEVVADEVKFLE 103
Cdd:PRK07274   81 KYE-KDGQTHYVTEVLCQSFQLLE 103
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 2-132 2.24e-22

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 87.21  E-value: 2.24e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   2 NRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRFSK-DG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQT 78
Cdd:PRK08486    3 NKVILVGNLTRDVELRYLPS-GSAIATIGLATSRRFKKqDGekGEEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLTF 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1443382284  79 RSYEAKDGTRRYVTEVVADEVKFLewgNKQSSGSQGfNNFESDPLSYNNEDNYN 132
Cdd:PRK08486   82 ESWMDQNGQKRSKHTITAESMQML---DSKSDNPQA-NAMQDNSFHENFNNNYP 131
PRK07772 PRK07772
single-stranded DNA-binding protein; Provisional
 4-117 4.04e-21

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236092 [Multi-domain]  Cd Length: 186  Bit Score: 83.93  E-value: 4.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   4 VVLIGRLTKDPELKFTPgTGTAVTTFVLA-VDRRFS------KDGknEADFIPVVVWGKQAESTANYMSKGKLIGISGRI 76
Cdd:PRK07772    7 ITVVGNLTADPELRFTP-SGAAVANFTVAsTPRTFDrqtnewKDG--EALFLRCSIWRQAAENVAESLTKGMRVIVTGRL 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1443382284  77 QTRSYEAKDGTRRYVTEVVADEV-KFLEWG----NKQSSGSQGFNN 117
Cdd:PRK07772   84 KQRSYETREGEKRTVVELEVDEIgPSLRYAtakvTRASRGGGGGGG 129
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 2-114 2.60e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 81.76  E-value: 2.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   2 NRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF----SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQ 77
Cdd:PRK06958    5 NKVILVGNLGADPEVRYLP-SGDAVANIRLATTDRYkdkaSGEFKEATEWHRVAFFGRLAEIVGEYLKKGSSVYIEGRIR 83

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1443382284  78 TRSYEAKDGTRRYVTEVVADEVKFLewGNKQSSGSQG 114
Cdd:PRK06958   84 TRKWQGQDGQDRYSTEIVADQMQML--GGRGGSGGGG 118
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
 1-127 7.80e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 80.33  E-value: 7.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLAVDRRfsKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTRS 80
Cdd:PRK06293    1 MMFGYIVGRLGADPEERMTSK-GKRVVVLRLGVKSR--VGSKDETVWCRCNIWGNRYDKMLPYLKKGSGVIVAGEMSPES 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1443382284  81 YEAKDGTRRYVTEVVADEVKFLEWGNKQSSGSQGFNNFESDPLSYNN 127
Cdd:PRK06293   78 YVDKDGSPQSSLVVSVDTIKFSPFGRNEGSRQPSAGEDEGQQRGYDN 124
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 1-122 1.36e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 77.28  E-value: 1.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF----SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRI 76
Cdd:PRK05733    5 VNKVILVGTCGQDPEVRYLP-NGNAVTNLSLATSEQWtdkqSGQKVERTEWHRVSLFGKVAEIAGEYLRKGSQVYIEGKL 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1443382284  77 QTRSYEaKDGTRRYVTEVVADEVKFLEW-----GNKQSSGSQGFNNFESDP 122
Cdd:PRK05733   84 QTREWE-KDGIKRYTTEIVVDMQGTMQLlggrpQGDDQGGQGGGNYNQSAP 133
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 1-122 6.18e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 74.34  E-value: 6.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKDgknEADFIPVVVWGKQAESTANYMSKGKLIGISGRIQTRS 80
Cdd:PRK07459    3 LNSVTLVGRAGRDPEVRYFE-SGSVVCNLTLAVNRRSRDD---EPDWFNLEIWGKTAQVAADYVKKGSLIGITGSLKFDR 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1443382284  81 YEAKD-GTRRYVTEVVADEVKFLewGNKQ-SSGSQGFNNFESDP 122
Cdd:PRK07459   79 WTDRNtGEDRSKPVIRVDRLELL--GSKRdSEGNANPSNSSEIP 120
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 1-95 2.44e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 74.00  E-value: 2.44e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDR--RFSKDG--KNEADFIPVVVWGKQAESTANYMSKGKLIGISGRI 76
Cdd:PRK13732    6 INKVILVGRLGKDPEVRYIP-NGGAVANLQVATSEswRDKQTGemREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQL 84

                          90
                  ....*....|....*....
gi 1443382284  77 QTRSYEaKDGTRRYVTEVV 95
Cdd:PRK13732   85 RTRSWE-DNGITRYVTEIL 102
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 1-114 7.20e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 72.66  E-value: 7.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLAV-DRRFSKDGKNE--ADFIPVVVWGKQAESTANYMSKGKLIGISGRIQ 77
Cdd:PRK08763    5 INKVILVGNLGNDPDIKYTQS-GMTITRISLATtSVRKDREGNTQerTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGSIR 83

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1443382284  78 TRSYEAKDGTRRYVTEVVADEVKFLEWGNKQSSGSQG 114
Cdd:PRK08763   84 YDKFTGQDGQERYVTEIVADEMQMLGGRGEGGGGGGG 120
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 1-132 2.87e-15

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 68.46  E-value: 2.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKDGKNE----ADFIPVVVWGKQAESTANYMSKGKLIGISGRI 76
Cdd:PRK06863    4 INKVIIVGHLGNDPEIRTMP-NGEAVANISVATSESWTDKNTGErrevTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRL 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1443382284  77 QTRSYEAKDGTRRYVTEVVADEVKFLEWGNKQSSGsqGFNNFESDPLSYNNEDNYN 132
Cdd:PRK06863   83 KTRKWQDQNGQDRYTTEIQGDVLQMLGGRNQRNAG--GYGNSGPAPQQSYQAGQTN 136
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 1-95 4.49e-15

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 68.33  E-value: 4.49e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRF----SKDGKNEADFIPVVVWGKQAESTANYMSKGKLIGISGRI 76
Cdd:PRK09010    6 VNKVILVGNLGQDPEVRYMP-NGGAVANITLATSESWrdkqTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQL 84

                          90
                  ....*....|....*....
gi 1443382284  77 QTRSYEAKDGTRRYVTEVV 95
Cdd:PRK09010   85 RTRKWTDQSGQDRYTTEVV 103
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 1-145 1.12e-11

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 58.58  E-value: 1.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKfTPGTGTAVTTFVLAVDR----RFSKDGKNEADFIPVVVWGKQAESTA-NYMSKGKLIGISGR 75
Cdd:PRK06642    5 LNKVILIGNVGRDPEIR-TTGEGKKIINLSLATTEtwkdRITSERKERTEWHRVVIFSEGLVSVVeRYVTKGSKLYIEGS 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1443382284  76 IQTRSYEAKDGTRRYVTEVVA----DEVKFLEWGN----KQSSGSQGFNNFESDPLSYNNEDnyNDDitpvdegEVPF 145
Cdd:PRK06642   84 LQTRKWNDNSGQEKYTTEVVLqnfnSQLILLDSKNsnnhNQDSGHSEYKHPETKNHSFDHSD--LDD-------EIPF 152
PRK05813 PRK05813
single-stranded DNA-binding protein; Provisional
 2-99 1.81e-08

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235616 [Multi-domain]  Cd Length: 219  Bit Score: 51.17  E-value: 1.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   2 NRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDRRFSKdgkneADFIPVVVWGKQAESTANyMSKGKLIGISGRIQTRSY 81
Cdd:PRK05813  110 NEIFLDGYICKEPVYRTTP-FGREIADLLLAVNRPYNK-----SDYIPCIAWGRNARFCKT-LEVGDNIRVWGRVQSREY 182

                          90
                  ....*....|....*...
gi 1443382284  82 EAKDGTRRYVTEvVADEV 99
Cdd:PRK05813  183 QKKLSEGEVVTK-VAYEV 199
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 1-95 1.51e-07

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 47.87  E-value: 1.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPgTGTAVTTFVLAVDR----RFSKDGKNEADFIPVVVWG----KQAEstaNYMSKGKLIGI 72
Cdd:PRK06341    5 VNKVILIGNLGADPEIRRTQ-DGRPIANLRIATSEtwrdRNSGERKEKTEWHRVVIFNeglcKVAE---QYLKKGAKVYI 80

                          90       100
                  ....*....|....*....|...
gi 1443382284  73 SGRIQTRSYEAKDGTRRYVTEVV 95
Cdd:PRK06341   81 EGQLQTRKWTDQSGVERYSTEVV 103
PriB COG2965
Primosomal replication protein N [Replication, recombination and repair];
1-80 2.19e-06

Primosomal replication protein N [Replication, recombination and repair];


Pssm-ID: 442205  Cd Length: 98  Bit Score: 43.25  E-value: 2.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443382284   1 MNRVVLIGRLTKDPELKFTPGtGTAVTTFVLavdRRFSKdgKNEADF-------IPVVVWGKQAESTANYmSKGKLIGIS 73
Cdd:COG2965     2 MNRLVLSGTVVERPALRYTPA-GIPVLEFVL---EHRSE--QQEAGLprqveceIPAVASGELAEKLARL-PLGSQVRVT 74


                  ....*..
gi 1443382284  74 GRIQTRS 80
Cdd:COG2965    75 GFLARKS 81
PRK05853 PRK05853
hypothetical protein; Validated
 35-99 3.81e-04

hypothetical protein; Validated


Pssm-ID: 235626  Cd Length: 161  Bit Score: 38.66  E-value: 3.81e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1443382284  35 RRFSKDGKNEAD---FIPVVVWGKQAESTANYMSKGKLIGISGRIQTRSYEAKDGTRRYVTEVVADEV 99
Cdd:PRK05853   29 RRRTADGGWEPGnslFITVNCWGRLVTGVGAALGKGAPVIVVGHVYTSEYEDRDGNRRSSLEMRATSV 96
DnaE COG0587
DNA polymerase III, alpha subunit [Replication, recombination and repair];
30-100 4.23e-03

DNA polymerase III, alpha subunit [Replication, recombination and repair];


Pssm-ID: 440352 [Multi-domain]  Cd Length: 1050  Bit Score: 36.20  E-value: 4.23e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1443382284   30 VLAVDRRFSKDGKN--------EADFIPVVVWGKQAESTANYMSKGKLIGISGRIQtrsyeakdgTRRYVTEVVADEVK 100
Cdd:COG0587    980 VTSRQRPGTKKGKRmafvtledETGSIEVVVFPEVYERYRRLLLEDRLLLVRGKVQ---------RRDGVVHLIAERIE 1049
PRK08182 PRK08182
single-stranded DNA-binding protein; Provisional
 49-102 7.55e-03

single-stranded DNA-binding protein; Provisional


Pssm-ID: 169261  Cd Length: 148  Bit Score: 34.66  E-value: 7.55e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1443382284  49 PVVVWGKQAESTANYMSKGKLIGISGRIQTRSYEAKDGTRRYVTEVVADEVKFL 102
Cdd:PRK08182   57 PVELWHRDAEHWARLYQKGMRVLVEGRMERDEWTDNEDNERVTFKVEARRVGIL 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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