|
Name |
Accession |
Description |
Interval |
E-value |
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
136-305 |
4.19e-58 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 184.67 E-value: 4.19e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 136 IKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQLAVPKEESE--IYSYQTAINNAMR 213
Cdd:cd01130 5 LRLAVRARKNILISGGTGSGKTTLLNALLSFIPPDERIVTIEDTRELQLPHPNVVHLLTRPGGGEkgEVTMADLLKAALR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 214 LRPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIITNIILGGglQNPDNKMLTELIITAIDFIIQISR 293
Cdd:cd01130 85 MRPDRIIVGEVRGGEAYDMLQAMNTGHPGSITTIHANSAEDAIDRLATLVLEAG--VNLDEEALRRLIASAIDVIVHVKR 162
|
170
....*....|..
gi 1443286041 294 nKKTGTRDITDI 305
Cdd:cd01130 163 -LGDGVRRVTEI 173
|
|
| VirB11 |
TIGR02788 |
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ... |
18-305 |
4.72e-55 |
|
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.
Pssm-ID: 274301 Cd Length: 308 Bit Score: 181.40 E-value: 4.72e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 18 YLEMEA-NELIFNKPCEIKVDKGDIWETIYDERLNYNFLETFLIELAIKRNQRFDEKHCHLSCELPYPFlryRVQAQHKT 96
Cdd:TIGR02788 1 FLDDEDvTEICINRPGEVWVEGPGGWQRFDVPDLTFSHLMRLARAIASFSKQSISEENPILSATLPGGE---RVQIVIPP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 97 SLFNSEICICVRIPSKSRFALENFV--------------LSDK------CLEKGWTYEKIKDLIKNKKNVLVSGGTGSGK 156
Cdd:TIGR02788 78 ACENDTVSITIRKPSLVDFSLDDYEekgffdtvraqsgtLSDNdeqlleLLDAGDIKEFLRLAIASRKNIIISGGTGSGK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 157 TSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQLAVPK--EESEIYSYQTAINNAMRLRPDRLFLGEIDIRNTFTFLR 234
Cdd:TIGR02788 158 TTFLKSLVDEIPKDERIITIEDTREIFLPHPNYVHLFYSKggQGLAKVTPKDLLQSCLRMRPDRIILGELRGDEAFDFIR 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1443286041 235 VNNTGHAGNLSTLHANNPEDA---IKAIITNIILGGGLqnpDNKMLTELIITAIDFIIQISRNKktGTRDITDI 305
Cdd:TIGR02788 238 AVNTGHPGSITTLHAGSPEEAfeqLALMVKSSQAGLGL---DFAYIVKLVREVIDIVVQINRRG--GGRKITEV 306
|
|
| CpaF |
COG4962 |
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ... |
12-305 |
2.87e-50 |
|
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 443988 [Multi-domain] Cd Length: 386 Bit Score: 171.12 E-value: 2.87e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 12 LNVLKPYLEMEA-NELIFNKPCEIKVDKGDIWEtiydeRLNYNF-----LETFLIELAIKRNQRFDEKHCHLSCELPypf 85
Cdd:COG4962 56 LGPLEPLLDDPDvTDIMVNGPDEVFVERGGRLE-----RTDVRFdseeeLRRLIERIAARVGRRLDESSPIVDARLP--- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 86 LRYRVQAQHK-TSLFNSeiCICVRIPSKSRFALENFV----LSDKCLEKgwtyekIKDLIKNKKNVLVSGGTGSGKTSFL 160
Cdd:COG4962 128 DGSRVNAVIPpVARDGP--SLSIRKFRKRPLTLEDLValgsLTPEMAEF------LRAAVRARLNILVSGGTGSGKTTLL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 161 NSLMSEIDPNERIVTIEDAQELYIENEN----KTQLAVPKEESEIySYQTAINNAMRLRPDRLFLGEidIRNT--FTFLR 234
Cdd:COG4962 200 NALSGFIPPDERIVTIEDAAELQLQHPHvvrlETRPPNVEGAGEV-TLRDLVRNALRMRPDRIIVGE--VRGAeaLDMLQ 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1443286041 235 VNNTGHAGNLSTLHANNPEDAIKAIITNIILGGglQNPDNKMLTELIITAIDFIIQISRNkKTGTRDITDI 305
Cdd:COG4962 277 AMNTGHDGSMSTLHANSARDALARLETLALMAG--ENLPREAVRRQIASAIDLVVHLERL-RDGRRRVTEI 344
|
|
| PRK13900 |
PRK13900 |
type IV secretion system ATPase VirB11; Provisional |
1-310 |
1.31e-39 |
|
type IV secretion system ATPase VirB11; Provisional
Pssm-ID: 184381 Cd Length: 332 Bit Score: 141.82 E-value: 1.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 1 MSNNTIVLNNILNVLKP-YLEMEANELIFNKPCEIKVD-KGDIW-ETIydERLNYNFLETFLIELAIKRNQRFDEKHCHL 77
Cdd:PRK13900 1 MTEEYAALETYLEPLKNiFAEDGVNEISINKPGEVWVEkKGDIRcEQI--PELDLSHLKALGRLVAQATEQKISEEKPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 78 SCELPYpflRYRVQAQHKTSLFNSEICICVRIPSKSRFALENF-------------------VLSDKCLEKGWTYEKIKD 138
Cdd:PRK13900 79 SATLPN---GYRIQIVFPPACEIGQIVYSIRKPSGMQLTLDDYekmgafdetateslvdeddVILNELLAEKKIKEFLEH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 139 LIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENE-NKTQLAVPK--EESEIYSYQTAINNAMRLR 215
Cdd:PRK13900 156 AVISKKNIIISGGTSTGKTTFTNAALREIPAIERLITVEDAREIVLSNHpNRVHLLASKggQGRAKVTTQDLIEACLRLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 216 PDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIITNIILGGGLQNPDNkmLTELIITAIDFIIQISRNK 295
Cdd:PRK13900 236 PDRIIVGELRGAEAFSFLRAINTGHPGSISTLHADSPAMAIEQLKLMVMQAGLGMPPDQ--IKKYILNVVDIVVQLKRGS 313
|
330
....*....|....*
gi 1443286041 296 KtGTRDITDILDLKN 310
Cdd:PRK13900 314 G-GKRYVSEIYFTKN 327
|
|
| T2SSE |
pfam00437 |
Type II/IV secretion system protein; This family contains components of both the Type II ... |
67-256 |
9.06e-31 |
|
Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.
Pssm-ID: 425681 [Multi-domain] Cd Length: 269 Bit Score: 116.62 E-value: 9.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 67 NQRFDEKHCHLSCELPYPFLR--YRVQAQHKTSLFnsEICICVRIPSKSrfaLENFVLSDKCLEkGWTYEKIKDLIKN-K 143
Cdd:pfam00437 57 RLDISERRPPQDGRLPLRIGGkgVRVRVSTLPTAG--GEKLVIRLLDPS---NVALSLDELGMT-GAQDEALLEFLRQpR 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 144 KNVLVSGGTGSGKTSFLNSLMSEID-PNERIVTIEDAQELYIENENKTQLaVPKEEseiYSYQTAINNAMRLRPDRLFLG 222
Cdd:pfam00437 131 GNILVTGPTGSGKTTTLYAALGELNtRDENIVTVEDPVEIQLEGINQVQL-NARAG---VTFADLLRAILRQDPDRIMVG 206
|
170 180 190
....*....|....*....|....*....|....*
gi 1443286041 223 EIDIRNTFTF-LRVNNTGHAGnLSTLHANNPEDAI 256
Cdd:pfam00437 207 EIRDLETAEIaLQAANTGHLV-LSTLHTNSAAGAL 240
|
|
| ATPase_ComGA |
NF041000 |
competence type IV pilus ATPase ComGA; |
132-256 |
1.39e-14 |
|
competence type IV pilus ATPase ComGA;
Pssm-ID: 468930 [Multi-domain] Cd Length: 265 Bit Score: 72.48 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 132 TYEKIKDLIKNKKN-VLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQElyIENENKTQLAVpKEESEIySYQTAINN 210
Cdd:NF041000 116 QFQLLKQLLQRRSGlILFSGPTGSGKTTTMYSLARKLALNKQVITIEDPVE--IKEPNFLQLQV-NEKAGM-TYDTLLKA 191
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1443286041 211 AMRLRPDRLFLGEidIRNTFT---FLRVNNTGHAgNLSTLHANNPEDAI 256
Cdd:NF041000 192 ALRHRPDILIIGE--IRDAETakaAIRAALTGHL-VLSTVHAKSAAGVI 237
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
143-225 |
1.86e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.12 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 143 KKNVLVSGGTGSGKTSFLNSLMSEIDPNER---IVTIEDAQELYIENENKTQLAVPKEESEIYSYQ-TAINNAMRLRPDR 218
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGgviYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLrLALALARKLKPDV 81
|
....*..
gi 1443286041 219 LFLGEID 225
Cdd:smart00382 82 LILDEIT 88
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
136-305 |
4.19e-58 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 184.67 E-value: 4.19e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 136 IKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQLAVPKEESE--IYSYQTAINNAMR 213
Cdd:cd01130 5 LRLAVRARKNILISGGTGSGKTTLLNALLSFIPPDERIVTIEDTRELQLPHPNVVHLLTRPGGGEkgEVTMADLLKAALR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 214 LRPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIITNIILGGglQNPDNKMLTELIITAIDFIIQISR 293
Cdd:cd01130 85 MRPDRIIVGEVRGGEAYDMLQAMNTGHPGSITTIHANSAEDAIDRLATLVLEAG--VNLDEEALRRLIASAIDVIVHVKR 162
|
170
....*....|..
gi 1443286041 294 nKKTGTRDITDI 305
Cdd:cd01130 163 -LGDGVRRVTEI 173
|
|
| VirB11 |
TIGR02788 |
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ... |
18-305 |
4.72e-55 |
|
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.
Pssm-ID: 274301 Cd Length: 308 Bit Score: 181.40 E-value: 4.72e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 18 YLEMEA-NELIFNKPCEIKVDKGDIWETIYDERLNYNFLETFLIELAIKRNQRFDEKHCHLSCELPYPFlryRVQAQHKT 96
Cdd:TIGR02788 1 FLDDEDvTEICINRPGEVWVEGPGGWQRFDVPDLTFSHLMRLARAIASFSKQSISEENPILSATLPGGE---RVQIVIPP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 97 SLFNSEICICVRIPSKSRFALENFV--------------LSDK------CLEKGWTYEKIKDLIKNKKNVLVSGGTGSGK 156
Cdd:TIGR02788 78 ACENDTVSITIRKPSLVDFSLDDYEekgffdtvraqsgtLSDNdeqlleLLDAGDIKEFLRLAIASRKNIIISGGTGSGK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 157 TSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQLAVPK--EESEIYSYQTAINNAMRLRPDRLFLGEIDIRNTFTFLR 234
Cdd:TIGR02788 158 TTFLKSLVDEIPKDERIITIEDTREIFLPHPNYVHLFYSKggQGLAKVTPKDLLQSCLRMRPDRIILGELRGDEAFDFIR 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1443286041 235 VNNTGHAGNLSTLHANNPEDA---IKAIITNIILGGGLqnpDNKMLTELIITAIDFIIQISRNKktGTRDITDI 305
Cdd:TIGR02788 238 AVNTGHPGSITTLHAGSPEEAfeqLALMVKSSQAGLGL---DFAYIVKLVREVIDIVVQINRRG--GGRKITEV 306
|
|
| CpaF |
COG4962 |
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ... |
12-305 |
2.87e-50 |
|
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 443988 [Multi-domain] Cd Length: 386 Bit Score: 171.12 E-value: 2.87e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 12 LNVLKPYLEMEA-NELIFNKPCEIKVDKGDIWEtiydeRLNYNF-----LETFLIELAIKRNQRFDEKHCHLSCELPypf 85
Cdd:COG4962 56 LGPLEPLLDDPDvTDIMVNGPDEVFVERGGRLE-----RTDVRFdseeeLRRLIERIAARVGRRLDESSPIVDARLP--- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 86 LRYRVQAQHK-TSLFNSeiCICVRIPSKSRFALENFV----LSDKCLEKgwtyekIKDLIKNKKNVLVSGGTGSGKTSFL 160
Cdd:COG4962 128 DGSRVNAVIPpVARDGP--SLSIRKFRKRPLTLEDLValgsLTPEMAEF------LRAAVRARLNILVSGGTGSGKTTLL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 161 NSLMSEIDPNERIVTIEDAQELYIENEN----KTQLAVPKEESEIySYQTAINNAMRLRPDRLFLGEidIRNT--FTFLR 234
Cdd:COG4962 200 NALSGFIPPDERIVTIEDAAELQLQHPHvvrlETRPPNVEGAGEV-TLRDLVRNALRMRPDRIIVGE--VRGAeaLDMLQ 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1443286041 235 VNNTGHAGNLSTLHANNPEDAIKAIITNIILGGglQNPDNKMLTELIITAIDFIIQISRNkKTGTRDITDI 305
Cdd:COG4962 277 AMNTGHDGSMSTLHANSARDALARLETLALMAG--ENLPREAVRRQIASAIDLVVHLERL-RDGRRRVTEI 344
|
|
| PRK13900 |
PRK13900 |
type IV secretion system ATPase VirB11; Provisional |
1-310 |
1.31e-39 |
|
type IV secretion system ATPase VirB11; Provisional
Pssm-ID: 184381 Cd Length: 332 Bit Score: 141.82 E-value: 1.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 1 MSNNTIVLNNILNVLKP-YLEMEANELIFNKPCEIKVD-KGDIW-ETIydERLNYNFLETFLIELAIKRNQRFDEKHCHL 77
Cdd:PRK13900 1 MTEEYAALETYLEPLKNiFAEDGVNEISINKPGEVWVEkKGDIRcEQI--PELDLSHLKALGRLVAQATEQKISEEKPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 78 SCELPYpflRYRVQAQHKTSLFNSEICICVRIPSKSRFALENF-------------------VLSDKCLEKGWTYEKIKD 138
Cdd:PRK13900 79 SATLPN---GYRIQIVFPPACEIGQIVYSIRKPSGMQLTLDDYekmgafdetateslvdeddVILNELLAEKKIKEFLEH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 139 LIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENE-NKTQLAVPK--EESEIYSYQTAINNAMRLR 215
Cdd:PRK13900 156 AVISKKNIIISGGTSTGKTTFTNAALREIPAIERLITVEDAREIVLSNHpNRVHLLASKggQGRAKVTTQDLIEACLRLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 216 PDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIITNIILGGGLQNPDNkmLTELIITAIDFIIQISRNK 295
Cdd:PRK13900 236 PDRIIVGELRGAEAFSFLRAINTGHPGSISTLHADSPAMAIEQLKLMVMQAGLGMPPDQ--IKKYILNVVDIVVQLKRGS 313
|
330
....*....|....*
gi 1443286041 296 KtGTRDITDILDLKN 310
Cdd:PRK13900 314 G-GKRYVSEIYFTKN 327
|
|
| TrbB_P |
TIGR02782 |
P-type conjugative transfer ATPase TrbB; The TrbB protein is found in the trb locus of ... |
107-310 |
2.47e-33 |
|
P-type conjugative transfer ATPase TrbB; The TrbB protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbB is a homolog of the vir system VirB11 ATPase, and the Flp pilus sytem ATPase TadA. [Cellular processes, Conjugation]
Pssm-ID: 274297 Cd Length: 299 Bit Score: 124.47 E-value: 2.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 107 VRIPSKSRFALENFVLSDKCLEKgwTYEKIKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEI---DPNERIVTIEDAQELY 183
Cdd:TIGR02782 98 IRKKAVAVFTLDDYVEAGIMTAA--QRDVLREAVLARKNILVVGGTGSGKTTLANALLAEIaknDPTDRVVIIEDTRELQ 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 184 IENENKTQLavpKEESEIYSYQTAINNAMRLRPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAiITNI 263
Cdd:TIGR02782 176 CAAPNVVQL---RTSDDAISMTRLLKATLRLRPDRIIVGEVRGGEALDLLKAWNTGHPGGIATIHANNAKAALDR-LEQL 251
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1443286041 264 ILGGGLQNPDnkmltELIITAIDFIIQISRNKKtgTRDITDILDLKN 310
Cdd:TIGR02782 252 IQEVSVTPMQ-----TLIAEAVDLVIFIARTPA--GRRVQEIAKVKG 291
|
|
| T2SSE |
pfam00437 |
Type II/IV secretion system protein; This family contains components of both the Type II ... |
67-256 |
9.06e-31 |
|
Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.
Pssm-ID: 425681 [Multi-domain] Cd Length: 269 Bit Score: 116.62 E-value: 9.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 67 NQRFDEKHCHLSCELPYPFLR--YRVQAQHKTSLFnsEICICVRIPSKSrfaLENFVLSDKCLEkGWTYEKIKDLIKN-K 143
Cdd:pfam00437 57 RLDISERRPPQDGRLPLRIGGkgVRVRVSTLPTAG--GEKLVIRLLDPS---NVALSLDELGMT-GAQDEALLEFLRQpR 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 144 KNVLVSGGTGSGKTSFLNSLMSEID-PNERIVTIEDAQELYIENENKTQLaVPKEEseiYSYQTAINNAMRLRPDRLFLG 222
Cdd:pfam00437 131 GNILVTGPTGSGKTTTLYAALGELNtRDENIVTVEDPVEIQLEGINQVQL-NARAG---VTFADLLRAILRQDPDRIMVG 206
|
170 180 190
....*....|....*....|....*....|....*
gi 1443286041 223 EIDIRNTFTF-LRVNNTGHAGnLSTLHANNPEDAI 256
Cdd:pfam00437 207 EIRDLETAEIaLQAANTGHLV-LSTLHTNSAAGAL 240
|
|
| PRK13894 |
PRK13894 |
conjugal transfer ATPase TrbB; Provisional |
133-308 |
8.57e-30 |
|
conjugal transfer ATPase TrbB; Provisional
Pssm-ID: 184377 Cd Length: 319 Bit Score: 115.22 E-value: 8.57e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 133 YEKIKDLIKNKKNVLVSGGTGSGKTSFLNSL---MSEIDPNERIVTIEDAQELYIENENKTQlavpkeeseiysYQTAIN 209
Cdd:PRK13894 138 REAIIAAVRAHRNILVIGGTGSGKTTLVNAIineMVIQDPTERVFIIEDTGEIQCAAENYVQ------------YHTSID 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 210 NAM--------RLRPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPE---DAIKAIITniilggglQNPDNKMLT 278
Cdd:PRK13894 206 VNMtallkttlRMRPDRILVGEVRGPEALDLLMAWNTGHEGGAATLHANNAKaglDRLKSLIS--------MHPDAPKPI 277
|
170 180 190
....*....|....*....|....*....|.
gi 1443286041 279 E-LIITAIDFIIQISRNKktGTRDITDILDL 308
Cdd:PRK13894 278 EpLIGEAVHVVVHIARTP--GGRRIQEILEV 306
|
|
| heli_sec_ATPase |
TIGR03819 |
helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct ... |
104-305 |
4.44e-29 |
|
helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.
Pssm-ID: 200328 Cd Length: 340 Bit Score: 113.97 E-value: 4.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 104 CICVRIPSKSRFALENFVLSDKCLEKGWTYekIKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELY 183
Cdd:TIGR03819 141 CLSLRVPRRRTFTLDELVAAGTIPPGVARL--LRALVAARLAFLVSGGTGSGKTTLLSALLALVPPDERIVLVEDAAELR 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 184 IENENKTQLAVPKEESE---IYSYQTAINNAMRLRPDRLFLGEI---DIRNTFTFLrvnNTGHAGNLSTLHANNPEDaIK 257
Cdd:TIGR03819 219 PDHPHVVRLEARPANVEgagAVTLTDLVRQALRMRPDRIVVGEVrgaEVVDLLAAL---NTGHDGGAGTLHANSPAD-VP 294
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1443286041 258 AIITNIILGGGLqnpDNKMLTELIITAIDFIIQISRNKKtGTRDITDI 305
Cdd:TIGR03819 295 ARLEALGALAGL---DRAALHSQLAAALDVVLHVRRTPR-GRRRVAEI 338
|
|
| VirB11 |
COG0630 |
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ... |
139-257 |
4.93e-28 |
|
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440395 [Multi-domain] Cd Length: 462 Bit Score: 112.87 E-value: 4.93e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 139 LIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQL----AVPKEESEIYSYQ--TAinnAM 212
Cdd:COG0630 286 LLENGKSVLVAGGTASGKTTLLNALLSFIPPDAKIVTIEDTRELNLPHENWISLvtreSFGGEEGDVTMFDllKA---AL 362
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1443286041 213 RLRPDRLFLGEIDIRNTFTFLRVNNTGHAGnLSTLHANNPEDAIK 257
Cdd:COG0630 363 RQRPDYIVVGEVRGEEAYTLFQAMATGHGV-LSTFHADSVESAIN 406
|
|
| type_II_IV_secretion_ATPases |
cd19477 |
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ... |
136-296 |
2.62e-26 |
|
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410885 [Multi-domain] Cd Length: 168 Bit Score: 102.09 E-value: 2.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 136 IKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIE-NENKTQLAVPKEeseiYSYQTAINNAMRL 214
Cdd:cd19477 3 IKDGIAIGKNVIVCGGTGSGKTTYIKSILEFIPKEERIISIEDTEEIVFKhHKNYTQLFFGGN----ITSADCLKSCLRQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 215 RPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIITNIILGGGLQNPDNKMLTELIITAIDFIIQISRN 294
Cdd:cd19477 79 RPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLAN*SSSNSAARNIKFESLIEGFKDLIDGIVHINHH 158
|
..
gi 1443286041 295 KK 296
Cdd:cd19477 159 KQ 160
|
|
| PRK13833 |
PRK13833 |
conjugal transfer protein TrbB; Provisional |
136-306 |
1.71e-24 |
|
conjugal transfer protein TrbB; Provisional
Pssm-ID: 172360 [Multi-domain] Cd Length: 323 Bit Score: 101.03 E-value: 1.71e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 136 IKDLIKNKKNVLVSGGTGSGKTSFLNSLMSEI---DPNERIVTIEDAQELYIENENktqlAVPKEESEIYSYQTAINNAM 212
Cdd:PRK13833 137 IRSAIDSRLNIVISGGTGSGKTTLANAVIAEIvasAPEDRLVILEDTAEIQCAAEN----AVALHTSDTVDMARLLKSTM 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 213 RLRPDRLFLGEIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIKAIitNIILGGGLQNPdnkmLTELIITAIDFIIQIS 292
Cdd:PRK13833 213 RLRPDRIIVGEVRDGAALTLLKAWNTGHPGGVTTIHSNTAMSALRRL--EQLTAEASQQP----MQEVIGEAVDLIVSIE 286
|
170
....*....|....
gi 1443286041 293 RNKKtgTRDITDIL 306
Cdd:PRK13833 287 RTGK--GRRVREVI 298
|
|
| PRK13851 |
PRK13851 |
type IV secretion system protein VirB11; Provisional |
14-289 |
3.62e-23 |
|
type IV secretion system protein VirB11; Provisional
Pssm-ID: 172375 Cd Length: 344 Bit Score: 97.66 E-value: 3.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 14 VLKPYLEM----EANELIFNKPCEIKVDKGDIWeTIYDERLNYNFLETFLIELAIKRNQRFDEKHCHLSCELPYPflrYR 89
Cdd:PRK13851 10 LLKPVLEWlddpRTEEVAINRPGEAFVRQAGVF-TKFPLPLSYDDLEDIAILAGALRKQDVGPRNPLCATELPGG---ER 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 90 VQAQHKTSLFNSEICICVRIPSkSRFALENFVlSDKCLEKGWTYEKIK------------------DL-------IKNKK 144
Cdd:PRK13851 86 LQICLPPTVPSGTVSLTIRRPS-SRVSELKEV-SSRYDASRWNQWQERrkrrdqldeailrhydngDLeaflhacVVGRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 145 NVLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQELYIENENKTQLAVPKEESEI--YSYQTAINNAMRLRPDRLFLG 222
Cdd:PRK13851 164 TMLLCGPTGSGKTTMSKTLISAIPPQERLITIEDTLELVIPHENHVRLLYSKNGAGLgaVTAEHLLQASLRMRPDRILLG 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 223 EIDIRNTFTFLRVNNTGHAGNLSTLHANNPEDAIK---AIITNIILGGGLqnpDNKMLTELIITAIDFII 289
Cdd:PRK13851 244 EMRDDAAWAYLSEVVSGHPGSISTIHGANPVQGFKklfSLVKSSAQGASL---EDRTLIDMLATAIDVIV 310
|
|
| PulE-GspE-like |
cd01129 |
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ... |
146-256 |
4.90e-18 |
|
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.
Pssm-ID: 410873 [Multi-domain] Cd Length: 159 Bit Score: 79.45 E-value: 4.90e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 146 VLVSGGTGSGKTSFLNSLMSEI-DPNERIVTIEDAQELYIENENktQLAVPKEESeiYSYQTAINNAMRLRPDRLFLGEi 224
Cdd:cd01129 14 ILVTGPTGSGKTTTLYAMLRELnGPERNIITIEDPVEYQIPGIN--QSQVNEKIG--LTFADALRAILRQDPDIIMVGE- 88
|
90 100 110
....*....|....*....|....*....|....*
gi 1443286041 225 dIRNTFT---FLRVNNTGHAgNLSTLHANNPEDAI 256
Cdd:cd01129 89 -IRDAETaeiAIRAALTGHL-VLSTLHTNDALGAI 121
|
|
| ATPase_ComGA |
NF041000 |
competence type IV pilus ATPase ComGA; |
132-256 |
1.39e-14 |
|
competence type IV pilus ATPase ComGA;
Pssm-ID: 468930 [Multi-domain] Cd Length: 265 Bit Score: 72.48 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 132 TYEKIKDLIKNKKN-VLVSGGTGSGKTSFLNSLMSEIDPNERIVTIEDAQElyIENENKTQLAVpKEESEIySYQTAINN 210
Cdd:NF041000 116 QFQLLKQLLQRRSGlILFSGPTGSGKTTTMYSLARKLALNKQVITIEDPVE--IKEPNFLQLQV-NEKAGM-TYDTLLKA 191
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1443286041 211 AMRLRPDRLFLGEidIRNTFT---FLRVNNTGHAgNLSTLHANNPEDAI 256
Cdd:NF041000 192 ALRHRPDILIIGE--IRDAETakaAIRAALTGHL-VLSTVHAKSAAGVI 237
|
|
| DotB_TraJ |
cd19516 |
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ... |
146-261 |
2.30e-14 |
|
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.
Pssm-ID: 410924 [Multi-domain] Cd Length: 179 Bit Score: 70.10 E-value: 2.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 146 VLVSGGTGSGKTSFLNSLMSEI----DPNERIVTIEDAQElYIENENKTQLAVPKeESEI----YSYQTAINNAMRLRPD 217
Cdd:cd19516 14 VYVAGATGSGKSTLLAAIYRYIlendPPDRKIITYEDPIE-FVYDGIKSKHSIIV-QSQIprhfKSFAKAVREALRRKPS 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1443286041 218 RLFLGEIDIRNTF-TFLRVNNTGHAgNLSTLHANNPEDAIKAIIT 261
Cdd:cd19516 92 LIGVGELRDQETIsAAVEASLTGHP-VYSTVHTKSVAETIRRLIS 135
|
|
| PilT |
cd01131 |
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ... |
133-260 |
3.53e-14 |
|
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.
Pssm-ID: 410875 [Multi-domain] Cd Length: 223 Bit Score: 70.26 E-value: 3.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 133 YEKIKDLIKNKKN-VLVSGGTGSGKTSFLNSLMSEIDPNER--IVTIEDAQElYIENENKTQLavpkEESEI----YSYQ 205
Cdd:cd01131 10 PPVLKDLALKPRGlVLVTGPTGSGKSTTLAAMIDYINETRSkhIITIEDPIE-FVHKHKKSLI----NQREVgrdtESFA 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1443286041 206 TAINNAMRLRPDRLFLGEIDIRNTFTF-LRVNNTGHAgNLSTLHANNPEDAIKAII 260
Cdd:cd01131 85 AALRAALREDPDVILVGEMRDLETIELaLTAAETGHL-VFSTLHTNSAAQTIDRII 139
|
|
| PilT |
COG2805 |
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ... |
19-259 |
1.68e-13 |
|
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];
Pssm-ID: 442056 Cd Length: 342 Bit Score: 70.12 E-value: 1.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 19 LEMEANELIF--NKPCEIKVDkGDIwETIYDERLNYNFLETFLIELAIKRN-QRFDEKH-CHLSCELPyPFLRYRVQA-Q 93
Cdd:COG2805 13 VEQGASDLHLtvGSPPMLRID-GEL-VPLDDPPLTPEDLEALLKEILTEEQrERLEEEGeLDFSYSLP-GLGRFRVNIfR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 94 HKTSlfnseICICVR-IPSKSRfALENFVLSdkclekgwtyEKIKDLIKNKKN-VLVSGGTGSGKTSFLNSLMSEIdpNE 171
Cdd:COG2805 90 QRGG-----VAAVLRlIPSEIP-TLEELGLP----------PVLKELAELPRGlVLVTGPTGSGKSTTLAAMIDYI--NE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 172 R----IVTIEDAQElYIENENK---TQLAVPkeeSEIYSYQTAINNAMRLRPDRLFLGEidIRNTFTF---LRVNNTGHa 241
Cdd:COG2805 152 TrakhIITIEDPIE-FVHKHKKsliNQREVG---RDTPSFANALRAALREDPDVILVGE--MRDLETIeaaLTAAETGH- 224
|
250 260
....*....|....*....|
gi 1443286041 242 gnL--STLHANnpeDAIKAI 259
Cdd:COG2805 225 --LvfATLHTN---SAAQTI 239
|
|
| PilU |
COG5008 |
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures]; |
134-260 |
1.58e-12 |
|
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
Pssm-ID: 444032 Cd Length: 370 Bit Score: 67.43 E-value: 1.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 134 EKIKDLIKNKKN-VLVSGGTGSGKTSflnSLMSEID-PNER----IVTIEDAQElYIeNENK----TQlavpkeeSEI-- 201
Cdd:COG5008 113 PVLKDLIMEKRGlVLFVGATGSGKST---TLAAMIDhRNENssghILTIEDPIE-FV-HKHKksivTQ-------REVgv 180
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1443286041 202 --YSYQTAINNAMRLRPDRLFLGEIDIRNTFTF-LRVNNTGHAGnLSTLHANNPEDAIKAII 260
Cdd:COG5008 181 dtESYEVALKNALRQAPDVILIGEIRDRETMEHaIAFAETGHLC-LATLHANNANQALDRII 241
|
|
| PulE |
COG2804 |
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ... |
105-259 |
1.34e-10 |
|
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442055 [Multi-domain] Cd Length: 561 Bit Score: 62.13 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 105 ICVRI--PSKSRFALENFVLSDKclekgwTYEKIKDLIKnKKN--VLVSGGTGSGKTSFLNSLMSEI-DPNERIVTIEDA 179
Cdd:COG2804 278 VVLRIldKSAALLDLEQLGFSPD------QLERLRRLIR-RPHgiILVTGPTGSGKTTTLYAALNELnTPERNIITVEDP 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 180 QELYIENENktqlavpkeeseiysyQTAIN--------NAMR--LR--PDRLFLGEidIRNTFT---FLRVNNTGHagnL 244
Cdd:COG2804 351 VEYQLPGIN----------------QVQVNpkigltfaSALRsiLRqdPDVIMVGE--IRDLETaeiAVQAALTGH---L 409
|
170
....*....|....*..
gi 1443286041 245 --STLHANnpeDAIKAI 259
Cdd:COG2804 410 vlSTLHTN---DAPSAI 423
|
|
| AAA_7 |
pfam12775 |
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ... |
139-176 |
1.78e-05 |
|
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).
Pssm-ID: 463698 [Multi-domain] Cd Length: 179 Bit Score: 44.30 E-value: 1.78e-05
10 20 30
....*....|....*....|....*....|....*...
gi 1443286041 139 LIKNKKNVLVSGGTGSGKTSFLNSLMSEIDPNERIVTI 176
Cdd:pfam12775 27 LLKNGKPVLLVGPTGTGKTVIIQNLLRKLDKEKYLPLF 64
|
|
| PRK10436 |
PRK10436 |
hypothetical protein; Provisional |
146-250 |
4.51e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 236694 Cd Length: 462 Bit Score: 44.92 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 146 VLVSGGTGSGKTSFLNSLMSEIDPNER-IVTIEDAQELYIENENKTQLAvPKEESEIYSYQTAInnaMRLRPDRLFLGEi 224
Cdd:PRK10436 221 ILVTGPTGSGKTVTLYSALQTLNTAQInICSVEDPVEIPLAGINQTQIH-PKAGLTFQRVLRAL---LRQDPDVIMVGE- 295
|
90 100
....*....|....*....|....*....
gi 1443286041 225 dIRNTFTF---LRVNNTGHAgNLSTLHAN 250
Cdd:PRK10436 296 -IRDGETAeiaIKAAQTGHL-VLSTLHTN 322
|
|
| FtsK_SpoIIIE |
pfam01580 |
FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from ... |
138-164 |
2.84e-04 |
|
FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE, which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.
Pssm-ID: 279863 [Multi-domain] Cd Length: 219 Bit Score: 41.59 E-value: 2.84e-04
10 20
....*....|....*....|....*..
gi 1443286041 138 DLIKNKKNVLVSGGTGSGKTSFLNSLM 164
Cdd:pfam01580 33 DLKKMPVHLLIAGATGSGKSVALNTLI 59
|
|
| COG4928 |
COG4928 |
Predicted P-loop ATPase, KAP-like [General function prediction only]; |
134-177 |
6.54e-04 |
|
Predicted P-loop ATPase, KAP-like [General function prediction only];
Pssm-ID: 443956 Cd Length: 386 Bit Score: 41.05 E-value: 6.54e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1443286041 134 EKIKDLIKNKKN-----VLVSGGTGSGKTSFLNSLMSEIDPNERIVTIE 177
Cdd:COG4928 15 ESLANLIKSSDAdeplvIGLDGEWGSGKTSFLNLIEKELESNEKVIVVY 63
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
146-186 |
1.50e-03 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 38.99 E-value: 1.50e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1443286041 146 VLVSGGTGSGKTSFLNSLMSEIDPNERIVTIED-----AQELYIEN 186
Cdd:cd03250 34 VAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGsiayvSQEPWIQN 79
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
143-225 |
1.86e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.12 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443286041 143 KKNVLVSGGTGSGKTSFLNSLMSEIDPNER---IVTIEDAQELYIENENKTQLAVPKEESEIYSYQ-TAINNAMRLRPDR 218
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGgviYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLrLALALARKLKPDV 81
|
....*..
gi 1443286041 219 LFLGEID 225
Cdd:smart00382 82 LILDEIT 88
|
|
| Udk |
COG0572 |
Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway ... |
146-177 |
4.74e-03 |
|
Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway/BioSystem: Pyrimidine salvage
Pssm-ID: 440337 [Multi-domain] Cd Length: 206 Bit Score: 37.51 E-value: 4.74e-03
10 20 30
....*....|....*....|....*....|..
gi 1443286041 146 VLVSGGTGSGKTSFLNSLMSEIdPNERIVTIE 177
Cdd:COG0572 10 IGIAGPSGSGKTTFARRLAEQL-GADKVVVIS 40
|
|
| |
