NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1443427591|emb|SUW36782|]
View 

chemotaxis protein MotB [Brucella abortus]

Protein Classification

flagellar motor protein MotB( domain architecture ID 11481934)

flagellar motor protein MotB (motility protein B) is required for the rotation of the flagellar motor

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
motB PRK05996
MotB family protein;
1-366 0e+00

MotB family protein;


:

Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 588.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591   1 MNIEPETKREIIIVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYFNPVKLMDRHSSPKG 80
Cdd:PRK05996    3 MEIHHEGKNEIIIVRRGGDDDHEGHHGGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVASYFNPIKLTDRKPSEKG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  81 VQNV------DQRDGKVRFESDQQVESSTKVVNDTTVRPASDQ---EERQLFREPYAMLAELAHETGVLQNQSAKGDGGT 151
Cdd:PRK05996   83 LKDPvdgaegEQKPGKSKFEEDQRVEGSSAVTGDDTTRTSGDQtnySEADLFRNPYAVLAEIAQEVGQQANVSAKGDGGA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 152 AQSGSASGADGGEAYRDPFSPDYWSSKA----VGDLTPP---------------APQTVPQTAPLPQAQPKKAETQEELI 212
Cdd:PRK05996  163 AQSGPATGADGGEAYRDPFDPDFWSKQVevttAGDLLPPgqareqaqgaksataAPATVPQAAPLPQAQPKKAATEEELI 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 213 ADLKKAATGEPAPNAGKAAKPEPMPD---------------------------VTVVPVEGGVMSQLTDKVDYGMFTIGS 265
Cdd:PRK05996  243 ADAKKAATGEPAANAAKAAKPEPMPDdqqkeaeqlqaaiaqaiggvagklaegVTVTPVEGGLLISLTDQVDYGMFAIGS 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 266 AKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATYDNRRLSSARAQMAYYMLVRGGLDEKRVLRVEGYADRHPK 345
Cdd:PRK05996  323 AVPRAELVLAMEKIGQLLAERPGAVIIRGHTDARPFKSATYDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFADRRPK 402

                         410       420
                  ....*....|....*....|.
gi 1443427591 346 NPNDPNAAENRRIDIFIKSKP 366
Cdd:PRK05996  403 LPNDPNAAANRRIEILIQSKQ 423
 
Name Accession Description Interval E-value
motB PRK05996
MotB family protein;
1-366 0e+00

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 588.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591   1 MNIEPETKREIIIVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYFNPVKLMDRHSSPKG 80
Cdd:PRK05996    3 MEIHHEGKNEIIIVRRGGDDDHEGHHGGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVASYFNPIKLTDRKPSEKG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  81 VQNV------DQRDGKVRFESDQQVESSTKVVNDTTVRPASDQ---EERQLFREPYAMLAELAHETGVLQNQSAKGDGGT 151
Cdd:PRK05996   83 LKDPvdgaegEQKPGKSKFEEDQRVEGSSAVTGDDTTRTSGDQtnySEADLFRNPYAVLAEIAQEVGQQANVSAKGDGGA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 152 AQSGSASGADGGEAYRDPFSPDYWSSKA----VGDLTPP---------------APQTVPQTAPLPQAQPKKAETQEELI 212
Cdd:PRK05996  163 AQSGPATGADGGEAYRDPFDPDFWSKQVevttAGDLLPPgqareqaqgaksataAPATVPQAAPLPQAQPKKAATEEELI 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 213 ADLKKAATGEPAPNAGKAAKPEPMPD---------------------------VTVVPVEGGVMSQLTDKVDYGMFTIGS 265
Cdd:PRK05996  243 ADAKKAATGEPAANAAKAAKPEPMPDdqqkeaeqlqaaiaqaiggvagklaegVTVTPVEGGLLISLTDQVDYGMFAIGS 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 266 AKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATYDNRRLSSARAQMAYYMLVRGGLDEKRVLRVEGYADRHPK 345
Cdd:PRK05996  323 AVPRAELVLAMEKIGQLLAERPGAVIIRGHTDARPFKSATYDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFADRRPK 402

                         410       420
                  ....*....|....*....|.
gi 1443427591 346 NPNDPNAAENRRIDIFIKSKP 366
Cdd:PRK05996  403 LPNDPNAAANRRIEILIQSKQ 423
MotB COG1360
Flagellar motor protein MotB [Cell motility];
238-366 7.04e-34

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 123.42  E-value: 7.04e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 238 DVTVVPVEGGVMSQLTDKVdygMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARA 316
Cdd:COG1360    43 QVEVRITEEGLVIEIQDRV---LFDSGSAELTPEGRELLDKIAAVLAEVPNRIRVEGHTDNVPISTARFpSNWELSAARA 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1443427591 317 QMAYYMLVRGGLDEKRvLRVEGYADRHPKNPND--PNAAENRRIDIFIKSKP 366
Cdd:COG1360   120 AAVVRYLIEGGVPPER-LSAVGYGDTRPLAPNDtpEGRARNRRVEIVILRRA 170
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 261-362 6.90e-22

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 89.15  E-value: 6.90e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 261 FTIGSAKPDARVVQMLERIAQVIARQPG-EVIISGHTDARPfkSATYdNRRLSSARAQMAYYMLVRGGLDEKRvLRVEGY 339
Cdd:cd07185     6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRG--SDAY-NQELSERRAEAVADYLVSKGVDASR-ITAVGY 81

                          90       100
                  ....*....|....*....|....*
gi 1443427591 340 ADRHPKNPND--PNAAENRRIDIFI 362
Cdd:cd07185    82 GESRPIASNDteEGRAKNRRVEIVI 106
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 15-67 9.42e-21

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 84.50  E-value: 9.42e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1443427591  15 RRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYFN 67
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQ 54
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 259-362 4.67e-20

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 85.05  E-value: 4.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDEKRVlRVE 337
Cdd:TIGR03350  32 ELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFpSNWHLSEARAKAVADVLAQAGGPAGRV-RAE 110

                          90       100
                  ....*....|....*....|....*..
gi 1443427591 338 GYADRHPKNPNDPNA--AENRRIDIFI 362
Cdd:TIGR03350 111 GRGDSEPIASNATAAgrARNRRVEIDV 137
 
Name Accession Description Interval E-value
motB PRK05996
MotB family protein;
1-366 0e+00

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 588.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591   1 MNIEPETKREIIIVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYFNPVKLMDRHSSPKG 80
Cdd:PRK05996    3 MEIHHEGKNEIIIVRRGGDDDHEGHHGGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVASYFNPIKLTDRKPSEKG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  81 VQNV------DQRDGKVRFESDQQVESSTKVVNDTTVRPASDQ---EERQLFREPYAMLAELAHETGVLQNQSAKGDGGT 151
Cdd:PRK05996   83 LKDPvdgaegEQKPGKSKFEEDQRVEGSSAVTGDDTTRTSGDQtnySEADLFRNPYAVLAEIAQEVGQQANVSAKGDGGA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 152 AQSGSASGADGGEAYRDPFSPDYWSSKA----VGDLTPP---------------APQTVPQTAPLPQAQPKKAETQEELI 212
Cdd:PRK05996  163 AQSGPATGADGGEAYRDPFDPDFWSKQVevttAGDLLPPgqareqaqgaksataAPATVPQAAPLPQAQPKKAATEEELI 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 213 ADLKKAATGEPAPNAGKAAKPEPMPD---------------------------VTVVPVEGGVMSQLTDKVDYGMFTIGS 265
Cdd:PRK05996  243 ADAKKAATGEPAANAAKAAKPEPMPDdqqkeaeqlqaaiaqaiggvagklaegVTVTPVEGGLLISLTDQVDYGMFAIGS 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 266 AKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATYDNRRLSSARAQMAYYMLVRGGLDEKRVLRVEGYADRHPK 345
Cdd:PRK05996  323 AVPRAELVLAMEKIGQLLAERPGAVIIRGHTDARPFKSATYDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFADRRPK 402

                         410       420
                  ....*....|....*....|.
gi 1443427591 346 NPNDPNAAENRRIDIFIKSKP 366
Cdd:PRK05996  403 LPNDPNAAANRRIEILIQSKQ 423
motB PRK09041
motility protein MotB;
6-365 5.67e-43

motility protein MotB;


Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 151.63  E-value: 5.67e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591   6 ETKREIII--VRRGGHddheAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYF-NPVKLmdrhsspkgvq 82
Cdd:PRK09041    4 ENHPPIVVkrVKKKGH----GHHGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIAEYFrTPLKV----------- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  83 nvdqrdgkvrfesdqqvesstkvvndttvrpasdqeerqlfrepyAMLaelahetgvlqnqsakgdGGTAQSGSASGADG 162
Cdd:PRK09041   69 ---------------------------------------------ALT------------------GGDRSSDSTSPIPG 85

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 163 GEAyrdpfspdywsskavgDLTPPAPQTVPQTAPLPQAQP--KKAETQ--EELIADLKKAATGEPAPnagKAAKPEPMPD 238
Cdd:PRK09041   86 GGD----------------DITQQDGEVNKQPNIAELAQGekERREQErlEKLKQELDQAIESNPKL---RQFKPQLLID 146

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 239 VTvvpvEGGVMSQLTDKVDYGMFTIGSA--KPDARvvQMLERIAQVIARQPGEVIISGHTDARPFKS--ATYDNRRLSSA 314
Cdd:PRK09041  147 LT----QEGLRIQIVDSQNRPMFATGSAevEPYMR--DILREIAPVLNDVPNRISLSGHTDATPYANgeKGYSNWELSAD 220

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1443427591 315 RAQMAYYMLVRGGLDEKRVLRVEGYADRHPKNPNDPNAAENRRIDIFIKSK 365
Cdd:PRK09041  221 RANASRRELVAGGMDEGKVLRVVGLASTMLLDKKDPLNPVNRRISIVVLNK 271
MotB COG1360
Flagellar motor protein MotB [Cell motility];
238-366 7.04e-34

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 123.42  E-value: 7.04e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 238 DVTVVPVEGGVMSQLTDKVdygMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARA 316
Cdd:COG1360    43 QVEVRITEEGLVIEIQDRV---LFDSGSAELTPEGRELLDKIAAVLAEVPNRIRVEGHTDNVPISTARFpSNWELSAARA 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1443427591 317 QMAYYMLVRGGLDEKRvLRVEGYADRHPKNPND--PNAAENRRIDIFIKSKP 366
Cdd:COG1360   120 AAVVRYLIEGGVPPER-LSAVGYGDTRPLAPNDtpEGRARNRRVEIVILRRA 170
PRK06778 PRK06778
hypothetical protein; Validated
 13-365 1.51e-30

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 117.72  E-value: 1.51e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  13 IVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEEtkaavasyfnpvklmdrhsspkgvqnvdqrdgkvr 92
Cdd:PRK06778    5 IIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKS----------------------------------- 49

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  93 fesdqqvesstkvvndttvrpasdqeERQlfrEPYAMLaelahetgvlqnqsakgDGGTAQSGsasgadGGEAYRDPFSP 172
Cdd:PRK06778   50 --------------------------ERE---SIIAAL-----------------HGQSIFNG------GGLSPLNKISP 77

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 173 DywsskavgdlTPPAPQTVPQTAPLPQAQPKKAETQEELIadlKKAAT--GEPAPNAGKAAKPEPMP---DVTVVPveGG 247
Cdd:PRK06778   78 S----------HPPKPATVAVPEETEKKARDVNEKTALLK---KKSATelGELATSINTIARDAHMEanlEMEIVP--QG 142

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 248 VMSQLTDKVDYGMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATYDNRRLSSARAQMAYYMLVRGG 327
Cdd:PRK06778  143 LRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAG 222

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1443427591 328 LDEKRVLRVEGYADRHPKNPNDPNAAENRRIDIFIKSK 365
Cdd:PRK06778  223 MPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTK 260
motB PRK12799
flagellar motor protein MotB; Reviewed
 11-365 7.84e-26

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 107.49  E-value: 7.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  11 IIIVRRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYF-NPVKLM----DRHSS-----PKG 80
Cdd:PRK12799    8 VILVKKRKTKHGAAHYGGSWKIAYADFMTAMMAFFLVMWLLAVSSPQELTQIAEYFrTPLKVAltsgDKSSSstspiPGG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  81 VQNVDQRDGKVRfesdQQVESSTkvvndttvrpaSDQEERQLfrepyamlaelahetgvlqnqsakgdggtaqsgsasga 160
Cdd:PRK12799   88 GDDPTQQVGEVR----KQINSEE-----------SRQEIHRL-------------------------------------- 114

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 161 dggeayrdpfspdywsskavgdltppapqtvpqtaplpqaqPKKAETQEELIadlkkaatgEPAPNAgKAAKPEPMPDVt 240
Cdd:PRK12799  115 -----------------------------------------NKLREKLDQLI---------ESDPRL-KALRPHLLINM- 142

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 241 vvpVEGGVMSQLTDKVDYGMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSAT--YDNRRLSSARAQM 318
Cdd:PRK12799  143 ---MDEGLRIQIIDSQNRPMFKMGSAQVEPYMRDILRAIAPILNDIPNKLSLSGHTDDLPYARGErgYSNWELSADRANA 219

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1443427591 319 AYYMLVRGGLDEKRVLRVEGYADRHPKNPNDPNAAENRRIDIFIKSK 365
Cdd:PRK12799  220 SRRELLAGGLDEGKILRVVGMASTMRLKEQASDDPVNRRISILVLNK 266
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 261-362 6.90e-22

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 89.15  E-value: 6.90e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 261 FTIGSAKPDARVVQMLERIAQVIARQPG-EVIISGHTDARPfkSATYdNRRLSSARAQMAYYMLVRGGLDEKRvLRVEGY 339
Cdd:cd07185     6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRG--SDAY-NQELSERRAEAVADYLVSKGVDASR-ITAVGY 81

                          90       100
                  ....*....|....*....|....*
gi 1443427591 340 ADRHPKNPND--PNAAENRRIDIFI 362
Cdd:cd07185    82 GESRPIASNDteEGRAKNRRVEIVI 106
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 15-67 9.42e-21

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 84.50  E-value: 9.42e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1443427591  15 RRGGHDDHEAHHGGVWKIAYADFMTAMMAFFLVLWLINAANEETKAAVASYFN 67
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESFQ 54
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 259-362 4.67e-20

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 85.05  E-value: 4.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDEKRVlRVE 337
Cdd:TIGR03350  32 ELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFpSNWHLSEARAKAVADVLAQAGGPAGRV-RAE 110

                          90       100
                  ....*....|....*....|....*..
gi 1443427591 338 GYADRHPKNPNDPNA--AENRRIDIFI 362
Cdd:TIGR03350 111 GRGDSEPIASNATAAgrARNRRVEIDV 137
motB PRK08944
flagellar motor protein MotB; Reviewed
 259-363 3.00e-19

flagellar motor protein MotB; Reviewed


Pssm-ID: 236356 [Multi-domain]  Cd Length: 302  Bit Score: 86.99  E-value: 3.00e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARA-QMAYYMLVRGGLDEKRvLRV 336
Cdd:PRK08944  181 GSFPSGSAFLQPKFKPVVRKIGELLKDVPGIITVSGHTDNVPISSELYrSNWDLSSARAvAVAHELLKVKGFDPQR-LKV 259

                          90       100
                  ....*....|....*....|....*....
gi 1443427591 337 EGYADRHPKNPNDP--NAAENRRIDIFIK 363
Cdd:PRK08944  260 VGMADTQPLVPNDTaeNRARNRRVEIIIE 288
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 145-365 3.94e-16

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 77.90  E-value: 3.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 145 AKGDGGTAQSGSASGADGGEAYRDPFSPDYWSSKAVGDLTPPAPQTVPQTAPLPQAQPKKAETQEELIADLKKAATGEPA 224
Cdd:COG2885    74 DAGSLSATAAAGAAALLVLLAALGALGAGLAALLLAIAAAASAAAADALALAAGAAAALGALGASAAAAAAALAAAKALG 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 225 PNAGKAAKPEPMPDVTVVPVEGGVMSQLTDKVDYG-MFTIGSAKPDARVVQMLERIAQVIARQPG-EVIISGHTDARPfk 302
Cdd:COG2885   154 DSAAAALDAAAKAEAAAAAAALLPAAVAEVVLLSNvYFDFDSAELTPEAKAALDELAALLKENPDlRIEIEGHTDSRG-- 231

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1443427591 303 SATYdNRRLSSARAQMAYYMLVRGGLDEKRvLRVEGYADRHPKNPNDPNA--AENRRIDIFIKSK 365
Cdd:COG2885   232 SDAY-NLALSERRAEAVKDYLVSKGIPASR-ITAVGYGESRPVASNDTEEgrAKNRRVEIVVLKK 294
PRK09038 PRK09038
flagellar motor protein MotD; Reviewed
 15-364 1.47e-15

flagellar motor protein MotD; Reviewed


Pssm-ID: 181618 [Multi-domain]  Cd Length: 281  Bit Score: 75.82  E-value: 1.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  15 RRGGHDDHEAHHGgvWKIAYADFMTAMMAFFLVLWLINAANEetkaavasyfnpvklmdrhsspkgvqnvdqrdGKVRFE 94
Cdd:PRK09038    4 RRKHHEEHENHER--WLVSYADFITLLFAFFVVMYAISSVNE--------------------------------GKYKVL 49

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591  95 SdqqvESSTKVVNDTtvrpasdqeERQLFREPyamlaelahetgvlqnqsakgdggtaqsgsasgadggeayrdpfspdy 174
Cdd:PRK09038   50 S----EALTGAFNGP---------SRSMKPIP------------------------------------------------ 68

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 175 wsskaVGDLTPPAPQTVPQTAPLPQAQPKKAETQEELIADLKKAATGePAPNAGKaakpepmpdVTVVPVEGGVMSQLTD 254
Cdd:PRK09038   69 -----IGKEQPKTTQPARPLVIDSEQPDARAQDQLKTIADDLRKALG-PLIESGQ---------VTVRRNELWIEIEINS 133

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 255 KVdygMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDEKRV 333
Cdd:PRK09038  134 SL---LFGSGDAMLSDQAFAILEKVAEVLKPAPNPIHVEGFTDNVPIATAQFpSNWELSAARAASVVRLLADDGVAPSRL 210

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1443427591 334 LRVeGYADRHPKNPNDPNA--AENRRIDIFIKS 364
Cdd:PRK09038  211 AAV-GYGEFQPVADNDTAEgrARNRRVVLVILR 242
PRK07033 PRK07033
DotU family type VI secretion system protein;
259-360 7.56e-15

DotU family type VI secretion system protein;


Pssm-ID: 180801 [Multi-domain]  Cd Length: 427  Bit Score: 75.09  E-value: 7.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDEKRVlRVE 337
Cdd:PRK07033  316 GLFASASTSVRDRYQPVLARVADALNQVKGNVLVTGYSDNVPIRTARFpSNWELSQARAQAVRALLAARLGQPERV-TAE 394

                          90       100
                  ....*....|....*....|....*
gi 1443427591 338 GYADRHPKNPNDP--NAAENRRIDI 360
Cdd:PRK07033  395 GRGDSDPVAPNDSaeNRARNRRVEI 419
PRK06742 PRK06742
flagellar motor protein MotS; Reviewed
 256-363 2.35e-13

flagellar motor protein MotS; Reviewed


Pssm-ID: 102525 [Multi-domain]  Cd Length: 225  Bit Score: 68.55  E-value: 2.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 256 VDYGMFTIGSA--KPDARvvQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSAR-AQMAYYMLVRGGLDEK 331
Cdd:PRK06742  114 VDNLIFDTGDAnvKPEAK--EIISQLVGFFQSVPNPIVVEGHTDSRPIHNDKFpSNWELSSARaANMIHHLIEVYNVDDK 191

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1443427591 332 RVLRVeGYADRHPKNPNDP--NAAENRRIDIFIK 363
Cdd:PRK06742  192 RLAAV-GYADTKPVVPNDSpqNWEKNRRVVIYIK 224
motB PRK08457
flagellar motor protein MotB; Reviewed
 245-363 2.51e-13

flagellar motor protein MotB; Reviewed


Pssm-ID: 181435 [Multi-domain]  Cd Length: 257  Bit Score: 68.97  E-value: 2.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 245 EGGVMSQLTDKVDYGM-----FTIGSAK-PDARVVQMLERIAQVIARQPG--EVIISGHTDARPFKSATY-DNRRLSSAR 315
Cdd:PRK08457  105 EGGALDQIDNGIALKLpskllFENGSAEiINADMMDYLKRIAKIITKLPKqvKINVRGYTDNSPLNKSRYkDHYELAAAR 184

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1443427591 316 AQMAYYMLVRGGLDEKRvLRVEGYADRHPKNPNDP--NAAENRRIDIFIK 363
Cdd:PRK08457  185 AYNVMKVLIQYGINPNR-LSFSSYGSNNPIAPNDSleNRLKNNRVEIFFK 233
PRK08126 PRK08126
hypothetical protein; Provisional
 260-362 3.12e-11

hypothetical protein; Provisional


Pssm-ID: 236157 [Multi-domain]  Cd Length: 432  Bit Score: 64.33  E-value: 3.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 260 MFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDEKRvLRVEG 338
Cdd:PRK08126  326 MFVPGQATVNPAMGPLIAKIAREIARVGGKVTVTGHTDNQPIRSAQFaSNLVLSEKRAAQVAQMLQSAGVPASR-LEAVG 404

                          90       100
                  ....*....|....*....|....*.
gi 1443427591 339 YADRHPKNPNDPNA--AENRRIDIFI 362
Cdd:PRK08126  405 KGDAQPVADNRTPQgrAQNRRVEITV 430
PRK06925 PRK06925
flagellar motor protein MotB;
245-363 3.44e-11

flagellar motor protein MotB;


Pssm-ID: 235887 [Multi-domain]  Cd Length: 230  Bit Score: 62.47  E-value: 3.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 245 EGGVMSQLTDKVdygMFTIGSAK--PDARVVqmLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQ-MAY 320
Cdd:PRK06925  109 ERGVVLVLQEAV---LFETGEADilKQAEPF--LHKIGVLLSTIPNDIKVEGHTDSRPISTYRYpSNWELSAARASsVIR 183

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1443427591 321 YMLVRGGLDEKRVLRVeGYADRHPKNPN--DPNAAENRRIDIFIK 363
Cdd:PRK06925  184 YFTSKEKLDSSRFIAV-GYADTKPVVPNttEENMQENRRVEIVIS 227
OmpA pfam00691
OmpA family; The Pfam entry also includes MotB and related proteins which are not included in ...
 261-357 6.16e-10

OmpA family; The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.


Pssm-ID: 425825 [Multi-domain]  Cd Length: 95  Bit Score: 55.44  E-value: 6.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 261 FTIGSAKPDARVVQMLERIAQVIA--RQPGEVIISGHTDARPfksATYDNRRLSSARAQMAYYMLVRGGLDEKRVLrVEG 338
Cdd:pfam00691   1 FDPGSSQLTPKAKATLDEIADLLKfpELKNTITIEGHTDTVG---SAAYNWELSQRRAEAVRRYLVNFGVPPSRIS-VVG 76

                          90
                  ....*....|....*....
gi 1443427591 339 YADRHPKNPNDPNAAENRR 357
Cdd:pfam00691  77 YGATKPITDNKTPEGRARN 95
motB PRK06667
flagellar motor protein MotB; Validated
 246-364 2.95e-08

flagellar motor protein MotB; Validated


Pssm-ID: 180652 [Multi-domain]  Cd Length: 252  Bit Score: 54.03  E-value: 2.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 246 GGVMSQLTDkvDYgmFTIGSAK---PDARVVqmLERIAQVIARQPGE---VIISGHTDA------RPFKSatydNRRLSS 313
Cdd:PRK06667  118 GLVISLASD--AF--FYPGSAEvklEENRET--LQKIASFIGFLDLAgrnFRIEGHTDNvdvnpeGPWKS----NWELSG 187

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1443427591 314 ARA-QMAYYMLVRGGLDEKRvLRVEGYADRHPKNPND-PNA-AENRRIDIFIKS 364
Cdd:PRK06667  188 ARAvNMLEYILNYGDQSESW-FQVSGFAGSRPLATEDtPEGrAYNRRIDIVILT 240
PRK14693 PRK14693
hypothetical protein; Provisional
 259-366 4.48e-07

hypothetical protein; Provisional


Pssm-ID: 173156 [Multi-domain]  Cd Length: 552  Bit Score: 51.69  E-value: 4.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVVQMLERIAQVIARQPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGLDE------- 330
Cdd:PRK14693  374 GAFDVGKANVRADFMHNIERLGLAFAPWPGDLEVIGHTDSRPIRTSEFpDNQALSEARARNVADELRKTALPGgarapen 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1443427591 331 --KRVLRVEGYADRHPKNPNDPNAA--ENRRIDIFIKSKP 366
Cdd:PRK14693  454 avQRNIEYSGRGDAQPIDTAKTAAAyeRNRRVDVLWKVIP 493
motB PRK07734
flagellar motor protein MotB; Reviewed
 194-362 7.42e-07

flagellar motor protein MotB; Reviewed


Pssm-ID: 236080 [Multi-domain]  Cd Length: 259  Bit Score: 49.74  E-value: 7.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 194 TAPLPQAQPKKAETQEELIADLKKAATgEPAPNAGKAAKPEPMPDVTVVP-----------VEGGVMSQLTDK------V 256
Cdd:PRK07734   63 TGVKDFLSDQKPEDEKELSASSLEAEQ-AKKKEEAEAKKKKEMEELKAVQkkidqyikekqLSSSLQTKLTEEgllitiL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 257 DYGMFTIGSA--KPDARvvqmleRIAQVIAR-----QPGEVIISGHTDARPFKSATY-DNRRLSSARAQMAYYMLVRGGL 328
Cdd:PRK07734  142 DNILFDSGKAdvRLEDL------PLAKEISNllvsnPPRNITISGHTDNVPIANAQFaSNWELSVMRAVNFMQVLLENKE 215

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1443427591 329 DEKRVLRVEGYADRHPKNPNDPNA--AENRRIDIFI 362
Cdd:PRK07734  216 LDPEKFSAKGYGEYKPIASNDTAEgrAKNRRVEVLI 251
PRK07034 PRK07034
hypothetical protein; Provisional
 259-363 1.48e-05

hypothetical protein; Provisional


Pssm-ID: 168775 [Multi-domain]  Cd Length: 536  Bit Score: 46.71  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 259 GMFTIGSAKPDARVV--QMLERIAQVIARQPGEVIISGHTDARPFKSATYDNR-RLSSARAQMAYYMLVRGGLDEKRVLR 335
Cdd:PRK07034  396 GAFRTGEATLSEEFInkKNIERLGLALAPWPGDIEVIGHTDNKPFRSTSGNNNlKLSAARASVVADKLRESTQINETHQR 475

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1443427591 336 VEGYADRHPKNPNDPNAAE-----NRRIDIFIK 363
Cdd:PRK07034  476 EISAIGRGESDPLADNATEegrkrNRRVDILWK 508
PRK09039 PRK09039
peptidoglycan -binding protein;
270-360 2.53e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443427591 270 ARVVQMLERIAQVIarqPGEV--II--SGHTDARPFKSATY--DNRRLSSARAQMAYYMLVRGGLDEKRvLRVEGYADRH 343
Cdd:PRK09039  244 AKLAAALIELAKEI---PPEInwVLrvDGHTDNVPLSGTGRfrDNWELSSARAISVVKFLIALGVPADR-LAAAGFGEFQ 319

                          90
                  ....*....|....*....
gi 1443427591 344 PKNPND-PNA-AENRRIDI 360
Cdd:PRK09039  320 PLDPGDtPEArARNRRIEL 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH