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Conserved domains on  [gi|1439757933|emb|STR14828|]
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ABC transporter permease [Klebsiella aerogenes]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.59e-88

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 265.78  E-value: 5.59e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFqnpDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVINPGP--------LEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALL 232
Cdd:COG0601   158 KLGWLPVSGRVSpwedfldaLRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1439757933 233 PALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRL 306
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.59e-88

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 265.78  E-value: 5.59e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFqnpDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVINPGP--------LEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALL 232
Cdd:COG0601   158 KLGWLPVSGRVSpwedfldaLRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1439757933 233 PALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRL 306
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-313 7.90e-50

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 167.95  E-value: 7.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFQNPDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:PRK10352   81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVINPGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALLPALNIAGL 240
Cdd:PRK10352  161 YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGM 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1439757933 241 LLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRLHLQTGGA 313
Cdd:PRK10352  241 HIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAH 313
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 129-306 1.58e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 81.58  E-value: 1.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 129 RWLSNFLQSLPVLFISLPTFWLGIALIQLFSFQLrwipvinpgpLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFV 208
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI----------LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 209 AVARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGF 288
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163

                         170
                  ....*....|....*...
gi 1439757933 289 VLINLLVDLVMPRLDPRL 306
Cdd:pfam00528 164 LLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 129-297 2.64e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.75  E-value: 2.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 129 RWLSNFLQSLPVLFISLPTFWLGIALIQLFSFQLRWipvinpGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFV 208
Cdd:cd06261    31 GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLV 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 209 AVARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTqqaVNNQDIAVLQAVVMISALGF 288
Cdd:cd06261   105 EAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGT---GLLLIFAILFPGDLGVAAAV 181


                  ....*....
gi 1439757933 289 VLINLLVDL 297
Cdd:cd06261   182 ALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.59e-88

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 265.78  E-value: 5.59e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFqnpDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVINPGP--------LEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALL 232
Cdd:COG0601   158 KLGWLPVSGRVSpwedfldaLRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1439757933 233 PALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRL 306
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-313 7.90e-50

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 167.95  E-value: 7.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFQNPDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:PRK10352   81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVINPGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALLPALNIAGL 240
Cdd:PRK10352  161 YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGM 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1439757933 241 LLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRLHLQTGGA 313
Cdd:PRK10352  241 HIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAH 313
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-304 1.10e-42

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 149.09  E-value: 1.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGD-AVLIKFQNPDlglsPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGD 79
Cdd:PRK15081    1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDpARLAAGPEAD----AQVVALVRQQLGLDQPLPHQFWHYISNALQGD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  80 FGYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFS 159
Cdd:PRK15081   77 FGTSMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFS 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 160 FQLRWIPVINPGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALLPALNIAG 239
Cdd:PRK15081  157 VELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMG 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1439757933 240 LLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDP 304
Cdd:PRK15081  237 LQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINP 301
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-306 5.26e-33

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 123.64  E-value: 5.26e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGdavlikfqNPDLG---LSPAQIAEMRLAYGADSPLWRQYLHTLLAMLH 77
Cdd:PRK09471    1 MLKFILRRCLEAIPTLFILITISFFMMRLAPG--------SPFTGertLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAH 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  78 GDFGYSLQ-AGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQ 156
Cdd:PRK09471   73 GDFGPSFKyKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 157 LFSFQLRWIPV--INPGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALLPA 234
Cdd:PRK09471  153 IFAITLHWLPGggWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPV 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1439757933 235 LNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRL 306
Cdd:PRK09471  233 LSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKI 304
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-306 2.58e-32

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 122.61  E-value: 2.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIkfQNPDLGLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDF 80
Cdd:PRK10914    1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMI--MAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:PRK10914   79 GISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPVI----------NPGPLEG---------------------LILPVIAVALPISAPLAQILMRSMDQVAVQPFVA 209
Cdd:PRK10914  159 HWNLTPVSgrvsdmvfldDSNPLTGfmlidtaiwgedgnfidavahMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIR 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 210 VARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFV 289
Cdd:PRK10914  239 TARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMII 318

                         330
                  ....*....|....*..
gi 1439757933 290 LINLLVDLVMPRLDPRL 306
Cdd:PRK10914  319 LVNLLVDLLYGVVNPRI 335
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-307 3.44e-30

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 116.48  E-value: 3.44e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFgqgLLVLwaaftLTFFLLQVLpgdAVLIKFQNPDLGLSpaqiaemrlaygaDSPLWRQYLHTLLAMLHGDF 80
Cdd:COG4168     1 MLIYLLRRL---NLLL-----ITLLILSLI---SFSLLYRDPLNPLS-------------DASLFSGYLFYLQNLLQGDF 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  81 GYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFSF 160
Cdd:COG4168    57 GISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSL 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 161 QLRWIPV---INP-------------------GP---------LEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFVA 209
Cdd:COG4168   137 NLGWLPVsgrYNLlyeippvtgfalidawlsdSPyrlkaiqsaLQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIK 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 210 VARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGFV 289
Cdd:COG4168   217 AAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVI 296

                         330
                  ....*....|....*...
gi 1439757933 290 LINLLVDLVMPRLDPRLH 307
Cdd:COG4168   297 IVNILSDILGALLNPLKR 314
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 1-306 6.90e-23

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 97.12  E-value: 6.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGDAVLIKFQNPDL-----------------------------------G 45
Cdd:PRK15133    1 MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEFgqagglpgaggegvrashaqtgvgnisdsnyrggrG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  46 LSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGDFGYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRL 125
Cdd:PRK15133   81 LDPEVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 126 PGLRWLSNFLQSLPVLFISLPTFWLGIALIQLFS-------FQLRWI--PVINPGPLEGLI--------LPVIAVALPIS 188
Cdd:PRK15133  161 RNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggsyfdlFPLRGLvsANFDSLPWYQKItdylwhitLPVLATVIGGF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 189 APLAQILMRS-MDQVAVQpFVAVARAKGMSETGVLWRHVMGNALLpaLNIAGL---LLGELIAGALITETVFGRSGLGQL 264
Cdd:PRK15133  241 AALTMLTKNSfLDEIRKQ-YVVTARAKGVSEKNILWKHVFRNAML--LVIAGFpatFISMFFTGSLLIEVMFSLNGLGLL 317

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1439757933 265 TQQAVNNQDIAVLQAVVMISALGFVLINLLVDLVMPRLDPRL 306
Cdd:PRK15133  318 GYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
PRK15110 PRK15110
peptide ABC transporter permease SapB;
64-307 2.18e-19

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 86.67  E-value: 2.18e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933  64 LWRQYLHTLLAMLHGDFGYSLQAGLAVSSLIASNLPDTLSLALPAFLLAVALAFALAFASRLPGLRWLSNFLQSLPVLFI 143
Cdd:PRK15110   40 LWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGF 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 144 SLPTFWLGIALIQLFSFQLRWIPV----------------------INPGP---------LEGLILPVIAVALPISAPLA 192
Cdd:PRK15110  120 SIPVFWLALLLTLFFSLTLGWLPVsgrfdllyevkpvtgfalidawLSDSPwrdemimsaIRHMILPVITLAVAPTTEVI 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 193 QILMRSMDQVAVQPFVAVARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQ 272
Cdd:PRK15110  200 RLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQ 279

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1439757933 273 DIAVLQAVVMISALGFVLINLLVDLVMPRLDPRLH 307
Cdd:PRK15110  280 DYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKH 314
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 129-306 1.58e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 81.58  E-value: 1.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 129 RWLSNFLQSLPVLFISLPTFWLGIALIQLFSFQLrwipvinpgpLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFV 208
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI----------LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 209 AVARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTQQAVNNQDIAVLQAVVMISALGF 288
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163

                         170
                  ....*....|....*...
gi 1439757933 289 VLINLLVDLVMPRLDPRL 306
Cdd:pfam00528 164 LLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 129-297 2.64e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.75  E-value: 2.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 129 RWLSNFLQSLPVLFISLPTFWLGIALIQLFSFQLRWipvinpGPLEGLILPVIAVALPISAPLAQILMRSMDQVAVQPFV 208
Cdd:cd06261    31 GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLV 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 209 AVARAKGMSETGVLWRHVMGNALLPALNIAGLLLGELIAGALITETVFGRSGLGQLTqqaVNNQDIAVLQAVVMISALGF 288
Cdd:cd06261   105 EAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGT---GLLLIFAILFPGDLGVAAAV 181


                  ....*....
gi 1439757933 289 VLINLLVDL 297
Cdd:cd06261   182 ALILLLLSL 190
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-101 1.60e-07

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 49.14  E-value: 1.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933   1 MSAYLLRRFGQGLLVLWAAFTLTFFLLQVLPGD-AVLIKFQNpdlgLSPAQIAEMRLAYGADSPLWRQYLHTLLAMLHGD 79
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDpARLACGKN----CTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGR 76

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1439757933  80 ------------FGYSLQAGLAVSSLIASNLPDT 101
Cdd:pfam19300  77 dfgavghcpapcLGYSFANNEPVWDTIMDRFPTT 110
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 129-262 4.52e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 38.17  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439757933 129 RWLSNFLQSLPVLFISLPTFWLGIALIQLFsfqlrwipvinpGPleGLILPVIAVALPISAPLAQIlMRSM-DQVAVQPF 207
Cdd:COG1173   108 GWVDAVLMRLVDVLLAFPSLLLAIALVAVL------------GP--GLLNVILALGLTGWPGYARL-VRAQvLSLREREY 172

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1439757933 208 VAVARAKGMSETGVLWRHVMGNALLPALNIAGLllgeLIAGALITETVFGRSGLG 262
Cdd:COG1173   173 VEAARALGASPLRIIFRHILPNVLPPLIVQATL----GIASAILAEAGLSFLGLG 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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