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Conserved domains on  [gi|1439331530|emb|STK37950|]
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transposase [Escherichia coli]

Protein Classification

transposase( domain architecture ID 1000873)

IS110 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0004803|GO:0003677|GO:0006313
PubMed:  16381877|10217489

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3547 super family cl34632
Transposase [Mobilome: prophages, transposons];
20-114 9.36e-18

Transposase [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG3547:

Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 76.88  E-value: 9.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439331530  20 NNTLYVGLDVHKESITVAYAINS-EPVELMGKIGTSPTDIQNLCKRLRSKSSQVSIVYEAGPC-GYGLYRRLVKSGFDCM 97
Cdd:COG3547     2 ETVIFVGIDVSKDTFDVAVVDEDgKVVLKVFRFANDRAGLLALLAWLKKLGPPCLVGMEATGGyHHWLARFLAAAGHEVV 81

                          90
                  ....*....|....*...
gi 1439331530  98 VCAPSLIPKKPGE-RVKT 114
Cdd:COG3547    82 VVNPRQVKAFRKGrRAKT 99
 
Name Accession Description Interval E-value
COG3547 COG3547
Transposase [Mobilome: prophages, transposons];
20-114 9.36e-18

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 76.88  E-value: 9.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439331530  20 NNTLYVGLDVHKESITVAYAINS-EPVELMGKIGTSPTDIQNLCKRLRSKSSQVSIVYEAGPC-GYGLYRRLVKSGFDCM 97
Cdd:COG3547     2 ETVIFVGIDVSKDTFDVAVVDEDgKVVLKVFRFANDRAGLLALLAWLKKLGPPCLVGMEATGGyHHWLARFLAAAGHEVV 81

                          90
                  ....*....|....*...
gi 1439331530  98 VCAPSLIPKKPGE-RVKT 114
Cdd:COG3547    82 VVNPRQVKAFRKGrRAKT 99
transpos_IS110 NF033542
IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type ...
 24-114 5.19e-13

IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.


Pssm-ID: 468073 [Multi-domain]  Cd Length: 345  Bit Score: 63.50  E-value: 5.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439331530  24 YVGLDVHKESITVAYAINSEPVELMGKIGTSPTDIQNLCKRLRSKSSQVSIVYEAGPCGYGLYRRLVKSG-FDCMVCAPS 102
Cdd:NF033542    1 FVGIDVAKEVFDVAVVDASGGEVLRKKFKNTKAGREALLAWLAKLAPPCVVVMEATGGYHAWLRELLALGgFPVVLVNPR 80

                          90
                  ....*....|...
gi 1439331530 103 LI-PKKPGERVKT 114
Cdd:NF033542   81 HVkPFRKGARAKT 93
 
Name Accession Description Interval E-value
COG3547 COG3547
Transposase [Mobilome: prophages, transposons];
20-114 9.36e-18

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 76.88  E-value: 9.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439331530  20 NNTLYVGLDVHKESITVAYAINS-EPVELMGKIGTSPTDIQNLCKRLRSKSSQVSIVYEAGPC-GYGLYRRLVKSGFDCM 97
Cdd:COG3547     2 ETVIFVGIDVSKDTFDVAVVDEDgKVVLKVFRFANDRAGLLALLAWLKKLGPPCLVGMEATGGyHHWLARFLAAAGHEVV 81

                          90
                  ....*....|....*...
gi 1439331530  98 VCAPSLIPKKPGE-RVKT 114
Cdd:COG3547    82 VVNPRQVKAFRKGrRAKT 99
transpos_IS110 NF033542
IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type ...
 24-114 5.19e-13

IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.


Pssm-ID: 468073 [Multi-domain]  Cd Length: 345  Bit Score: 63.50  E-value: 5.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1439331530  24 YVGLDVHKESITVAYAINSEPVELMGKIGTSPTDIQNLCKRLRSKSSQVSIVYEAGPCGYGLYRRLVKSG-FDCMVCAPS 102
Cdd:NF033542    1 FVGIDVAKEVFDVAVVDASGGEVLRKKFKNTKAGREALLAWLAKLAPPCVVVMEATGGYHAWLRELLALGgFPVVLVNPR 80

                          90
                  ....*....|...
gi 1439331530 103 LI-PKKPGERVKT 114
Cdd:NF033542   81 HVkPFRKGARAKT 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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