|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-293 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 538.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKME 80
Cdd:PRK15127 575 MVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRA 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:PRK15127 655 FSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNGLEDTPQFKIDIDQE 734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:PRK15127 735 KAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSP 814
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER 293
Cdd:PRK15127 815 RLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQER 867
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-300 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 535.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKME 80
Cdd:TIGR00915 575 IVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGKENSVFAIAGRATGH 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:TIGR00915 655 FMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNGLEDEPQLKIDIDRE 733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:TIGR00915 734 KAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPFSAFATVRWEYGSP 813
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER--GDAANLL 300
Cdd:TIGR00915 814 QLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERlsGSQAPAL 875
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-301 |
3.80e-129 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 392.04 E-value: 3.80e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLnnEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERSGDENSAEAVIHRAK 78
Cdd:pfam00873 564 SAQLPPGVSLDQTQRVMKQVEKILK--EKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERPGPEKSVQALIERLR 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 79 MELGKIRDGFVIPFNMPAIVELGTATGFDFELID-QAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEV 157
Cdd:pfam00873 642 KALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDVRSDGQEDQPQLQVNI 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 158 DQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY 237
Cdd:pfam00873 721 DREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKIEWGY 800
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1413277693 238 GSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERGDAANLLI 301
Cdd:pfam00873 801 GPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPI 866
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-293 |
4.50e-97 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 307.03 E-value: 4.50e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEkaNVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERsgdENSAEAVIHRAKME 80
Cdd:COG0841 563 SVQLPPGTSLERTEAVVRQVEEILLEVP--EVESVFSVVGFSGGGSGSNSGTIFVTLKPWDER---DRSADEIIARLREK 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIvELGTATGFDFELidqAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:COG0841 638 LAKIPGARVFVFQPPAG-GLGSGAPIEVQL---QGDDLEELAAAAEKLLAALRQIPG-LVDVRSDLQLGKPELQLDIDRE 712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:COG0841 713 KAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPS 792
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQER 293
Cdd:COG0841 793 SINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQ 847
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
1-301 |
9.23e-42 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 153.63 E-value: 9.23e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVL------DQVTDY-YLNNEKANVESVFT-----VNGFSFSGQAQ----NAGMAFVSLKPWEERs 64
Cdd:NF033617 541 YVFIPKELAPSEDRGVIfgmiqaPQSISLdYMSAKMRDVEKILSsdpevQSLTSFNGVGGnpgdNTGFGIINLKPWDER- 619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 65 gdENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVeLGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPaSLVSVRP 144
Cdd:NF033617 620 --DVSAQEIIDRLRPKLAKVPGMDLFLFPLQDLP-GGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDS 695
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 145 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEM 224
Cdd:NF033617 696 DLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKL 775
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 225 VPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM-ALMENLASKLPAGIGYDWTGMS--YQERGDAANLLI 301
Cdd:NF033617 776 VPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIeALDQAAKELLPSGISGSFQGAAraFQEEGSSLLFLF 855
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-293 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 538.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKME 80
Cdd:PRK15127 575 MVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRA 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:PRK15127 655 FSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNGLEDTPQFKIDIDQE 734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:PRK15127 735 KAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSP 814
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER 293
Cdd:PRK15127 815 RLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQER 867
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-300 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 535.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKME 80
Cdd:TIGR00915 575 IVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGKENSVFAIAGRATGH 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:TIGR00915 655 FMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNGLEDEPQLKIDIDRE 733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:TIGR00915 734 KAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPFSAFATVRWEYGSP 813
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER--GDAANLL 300
Cdd:TIGR00915 814 QLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERlsGSQAPAL 875
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
2-293 |
1.80e-135 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 408.83 E-value: 1.80e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 2 IQLPAGATQERTQKVLDQVTDYYLNNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKMEL 81
Cdd:PRK10555 575 VQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKTGTSFAIIERATKAF 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 82 GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPaSLVSVRPNGLEDTAQFKLEVDQEK 161
Cdd:PRK10555 655 NKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNP-ELTRVRHNGLDDSPQLQIDIDQRK 733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 162 AQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPR 241
Cdd:PRK10555 734 AQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPR 813
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1413277693 242 LERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER 293
Cdd:PRK10555 814 LERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQER 865
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-301 |
3.80e-129 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 392.04 E-value: 3.80e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLnnEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERSGDENSAEAVIHRAK 78
Cdd:pfam00873 564 SAQLPPGVSLDQTQRVMKQVEKILK--EKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERPGPEKSVQALIERLR 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 79 MELGKIRDGFVIPFNMPAIVELGTATGFDFELID-QAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEV 157
Cdd:pfam00873 642 KALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDVRSDGQEDQPQLQVNI 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 158 DQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY 237
Cdd:pfam00873 721 DREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKIEWGY 800
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1413277693 238 GSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERGDAANLLI 301
Cdd:pfam00873 801 GPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPI 866
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-293 |
4.50e-97 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 307.03 E-value: 4.50e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEkaNVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERsgdENSAEAVIHRAKME 80
Cdd:COG0841 563 SVQLPPGTSLERTEAVVRQVEEILLEVP--EVESVFSVVGFSGGGSGSNSGTIFVTLKPWDER---DRSADEIIARLREK 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIvELGTATGFDFELidqAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:COG0841 638 LAKIPGARVFVFQPPAG-GLGSGAPIEVQL---QGDDLEELAAAAEKLLAALRQIPG-LVDVRSDLQLGKPELQLDIDRE 712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:COG0841 713 KAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPS 792
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQER 293
Cdd:COG0841 793 SINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQ 847
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-300 |
5.93e-94 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 299.07 E-value: 5.93e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKanVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKME 80
Cdd:PRK09577 572 MVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAARDHVQAIVARINER 649
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 81 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQE 160
Cdd:PRK09577 650 FAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPA-LTDLMFAGTQDAPQLKLDIDRA 728
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 161 KAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 240
Cdd:PRK09577 729 KASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLAAFATLHWTLGPP 808
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1413277693 241 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQER--GDAANLL 300
Cdd:PRK09577 809 QLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERlsGAQAPML 870
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
1-301 |
9.23e-42 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 153.63 E-value: 9.23e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVL------DQVTDY-YLNNEKANVESVFT-----VNGFSFSGQAQ----NAGMAFVSLKPWEERs 64
Cdd:NF033617 541 YVFIPKELAPSEDRGVIfgmiqaPQSISLdYMSAKMRDVEKILSsdpevQSLTSFNGVGGnpgdNTGFGIINLKPWDER- 619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 65 gdENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVeLGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPaSLVSVRP 144
Cdd:NF033617 620 --DVSAQEIIDRLRPKLAKVPGMDLFLFPLQDLP-GGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDS 695
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 145 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEM 224
Cdd:NF033617 696 DLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKL 775
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 225 VPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM-ALMENLASKLPAGIGYDWTGMS--YQERGDAANLLI 301
Cdd:NF033617 776 VPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIeALDQAAKELLPSGISGSFQGAAraFQEEGSSLLFLF 855
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-291 |
8.05e-22 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 95.67 E-value: 8.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 1 MIQLPAGATQERTQKVLDQVTDYYLNNEKANVE--SVFTVNGFSfsgqAQNAGMAFVSLKPWEERsgdENSAEAVIHRAK 78
Cdd:PRK09579 557 IIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEyySSFQINGFN----GVQSGIGGFLLKPWNER---ERTQMELLPLVQ 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 79 MELGKIRDGFVIPFNMPAIVelGTATGFDFELIDQAGLGHDALTQARNQLlGMAAQHPASLVSVRPNGLEDTAQFKLEVD 158
Cdd:PRK09579 630 AKLEEIPGLQIFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQRV-KQRAQESGKFAFLDIDLAFDKPEVVVDID 706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 159 QEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYG 238
Cdd:PRK09579 707 RAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRAR 786
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1413277693 239 SPRLERYNGLPSMEIQGeaAPGTSSGDAMALMENLA-SKLPAGIGYDWTGMSYQ 291
Cdd:PRK09579 787 PRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIArEEAPEGFAFDYAGASRQ 838
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
34-235 |
9.21e-09 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 56.27 E-value: 9.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 34 SVFTVNGFSfSGQAQNAGMAFVSLKPWEERSgdeNSAEAVIHRAKMELGKIRDG--FVIPFNMPAIVELGTATGFDFELI 111
Cdd:PRK10614 591 AVDNVTGFT-GGSRVNSGMMFITLKPLSERS---ETAQQVIDRLRVKLAKEPGAnlFLMAVQDIRVGGRQSNASYQYTLL 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 112 DQAglgHDALTQARNQLLGMAAQHPaSLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 191
Cdd:PRK10614 667 SDD---LAALREWEPKIRKALAALP-ELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQP 742
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1413277693 192 GRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFttSHW 235
Cdd:PRK10614 743 LNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYF--AKW 784
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
152-228 |
4.22e-08 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 54.26 E-value: 4.22e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1413277693 152 QFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFS 228
Cdd:COG3696 717 QLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
32-281 |
3.21e-06 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 48.57 E-value: 3.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 32 VESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSgdeNSAEAVIHRAKMELGKIRDG--FVIPFNMPAIVELGTATGFDFE 109
Cdd:PRK10503 602 VQSLTSFVGVDGTNPSLNSARLQINLKPLDERD---DRVQKVIARLQTAVAKVPGVdlYLQPTQDLTIDTQVSRTQYQFT 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 110 LidQAGlGHDALTQARNQLLGMAAQHPAsLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNdfi 189
Cdd:PRK10503 679 L--QAT-SLDALSTWVPKLMEKLQQLPQ-LSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLIS--- 751
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 190 drgrvkKVYVQADAKFRMLPEDV---------DKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG 260
Cdd:PRK10503 752 ------TIYTQANQYRVVLEHNTentpglaalDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDG 825
|
250 260
....*....|....*....|...
gi 1413277693 261 TSSGDAMALMENLASKL--PAGI 281
Cdd:PRK10503 826 YSLGDAVQAIMDTEKTLnlPADI 848
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
156-284 |
4.67e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 41.63 E-value: 4.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413277693 156 EVDQEKAQALGVSLSDINQTISTAlggtyvNDFIDRGRVK----KVYVQADAKFRmLPEDVDKLYVRSANGEMVPFSAFT 231
Cdd:COG0841 187 WLDPDKLAAYGLTLADVANAIRAQ------NVDVPAGRIGggdrEYTVRTNGRLK-TPEEFENIVIRTNDGSVVRLGDVA 259
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1413277693 232 TSHWVYGSPRLE-RYNGLPSMEIQGEAAPGTSSGDAM----ALMENLASKLPAGIGYD 284
Cdd:COG0841 260 RVEDGAEDYRSIaRLNGKPAVGLAIQKQPGANALEVAdavrAKLEELQASLPEGVELT 317
|
|
| |
