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Conserved domains on  [gi|1413331934|emb|SRM22657|]
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SoxR reducing system protein RseC [Shigella flexneri]

Protein Classification

SoxR reducing system protein RseC( domain architecture ID 10013667)

SoxR reducing system protein RseC is involved in reduction of the iron-sulfur cluster regulatory protein SoxR

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10862 PRK10862
SoxR-reducing system protein RseC;
1-154 2.42e-97

SoxR-reducing system protein RseC;


:

Pssm-ID: 182788  Cd Length: 154  Bit Score: 277.23  E-value: 2.42e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   1 MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALL 80
Cdd:PRK10862    1 MIKEWATVVSWQNGIALLRCEVKAGCSSCASRAGCGSRLLNKLGPQTTHQLVVPSSQPLVPGQKVELGIAEGSLLRSALL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  81 VYMSPLVGLFLIASLFQLLFASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSS 154
Cdd:PRK10862   81 VYMTPLVGLFLGAALFQLLFGSDLAALCGALLGGVGGFLLARGLSRKLAARAAYQPVILQVALPPDLLRVETSS 154
 
Name Accession Description Interval E-value
PRK10862 PRK10862
SoxR-reducing system protein RseC;
1-154 2.42e-97

SoxR-reducing system protein RseC;


Pssm-ID: 182788  Cd Length: 154  Bit Score: 277.23  E-value: 2.42e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   1 MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALL 80
Cdd:PRK10862    1 MIKEWATVVSWQNGIALLRCEVKAGCSSCASRAGCGSRLLNKLGPQTTHQLVVPSSQPLVPGQKVELGIAEGSLLRSALL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  81 VYMSPLVGLFLIASLFQLLFASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSS 154
Cdd:PRK10862   81 VYMTPLVGLFLGAALFQLLFGSDLAALCGALLGGVGGFLLARGLSRKLAARAAYQPVILQVALPPDLLRVETSS 154
RseC COG3086
RseC, positive regulator of sigma E activity [Signal transduction mechanisms];
1-142 1.49e-55

RseC, positive regulator of sigma E activity [Signal transduction mechanisms];


Pssm-ID: 442320  Cd Length: 149  Bit Score: 171.22  E-value: 1.49e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   1 MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALL 80
Cdd:COG3086     1 MIEETGTVVAVEGGTAWVETQRKSACGSCAAKSGCGTGLLSKLFPSKEHRLEVPNPLGLKVGDRVEVGIPESSLLKAALL 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  81 VYMSPLVGLFLIASLFQLL--FASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVA 142
Cdd:COG3086    81 VYLLPLLGLLLGALLGQALgpGGSELLAALGGLLGLALGFLLARRLSRRLAKKSKYQPVILRIL 144
RseC_MucC pfam04246
Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins ...
8-140 3.96e-39

Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteriztic of chronic respiratory tract colonization in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.


Pssm-ID: 461236  Cd Length: 130  Bit Score: 128.85  E-value: 3.96e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   8 VVSWQNGQALVSCDVKASCSSCASRAGCGSrvlnKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLV 87
Cdd:pfam04246   1 VVAVEGGTAWVEIERKSACGSCAARSGCKL----GASGSKEKIIEVANPIGAKVGDRVEVGIPESSLLKAALLVYLLPLL 76
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  88 GLFLIASLFQ-LLFASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILS 140
Cdd:pfam04246  77 GLILGALLGQaLLGGSELAAALGGLLGLALGFLILRLLDRRLKKKGKFQPVILR 130
 
Name Accession Description Interval E-value
PRK10862 PRK10862
SoxR-reducing system protein RseC;
1-154 2.42e-97

SoxR-reducing system protein RseC;


Pssm-ID: 182788  Cd Length: 154  Bit Score: 277.23  E-value: 2.42e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   1 MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALL 80
Cdd:PRK10862    1 MIKEWATVVSWQNGIALLRCEVKAGCSSCASRAGCGSRLLNKLGPQTTHQLVVPSSQPLVPGQKVELGIAEGSLLRSALL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  81 VYMSPLVGLFLIASLFQLLFASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSS 154
Cdd:PRK10862   81 VYMTPLVGLFLGAALFQLLFGSDLAALCGALLGGVGGFLLARGLSRKLAARAAYQPVILQVALPPDLLRVETSS 154
RseC COG3086
RseC, positive regulator of sigma E activity [Signal transduction mechanisms];
1-142 1.49e-55

RseC, positive regulator of sigma E activity [Signal transduction mechanisms];


Pssm-ID: 442320  Cd Length: 149  Bit Score: 171.22  E-value: 1.49e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   1 MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALL 80
Cdd:COG3086     1 MIEETGTVVAVEGGTAWVETQRKSACGSCAAKSGCGTGLLSKLFPSKEHRLEVPNPLGLKVGDRVEVGIPESSLLKAALL 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  81 VYMSPLVGLFLIASLFQLL--FASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVA 142
Cdd:COG3086    81 VYLLPLLGLLLGALLGQALgpGGSELLAALGGLLGLALGFLLARRLSRRLAKKSKYQPVILRIL 144
RseC_MucC pfam04246
Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins ...
8-140 3.96e-39

Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteriztic of chronic respiratory tract colonization in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.


Pssm-ID: 461236  Cd Length: 130  Bit Score: 128.85  E-value: 3.96e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413331934   8 VVSWQNGQALVSCDVKASCSSCASRAGCGSrvlnKLGPQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLV 87
Cdd:pfam04246   1 VVAVEGGTAWVEIERKSACGSCAARSGCKL----GASGSKEKIIEVANPIGAKVGDRVEVGIPESSLLKAALLVYLLPLL 76
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1413331934  88 GLFLIASLFQ-LLFASDVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILS 140
Cdd:pfam04246  77 GLILGALLGQaLLGGSELAAALGGLLGLALGFLILRLLDRRLKKKGKFQPVILR 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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