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Conserved domains on  [gi|1052974471|emb|SCG96115|]
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Prolyl tripeptidyl peptidase precursor [uncultured Bacteroides sp.]

Protein Classification

S9 family peptidase( domain architecture ID 13559775)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
533-786 1.02e-53

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


:

Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 185.61  E-value: 1.02e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 533 VKAADGVTdLYGIMYKPFDfdsTKVYPIIDYVYPGPQveAVDYPFRRMSvrtDRLAQAGFIVITVGQRGghpsrskwyhn 612
Cdd:COG1506     2 FKSADGTT-LPGWLYLPAD---GKKYPVVVYVHGGPG--SRDDSFLPLA---QALASRGYAVLAPDYRG----------- 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 613 YGY--GNMRDYPLADHKAAVEQLAARyPFIDITRVGIHGHSGGGFMSTAAICQYPDFYKAAVSCAGNHDNRIYN---RWW 687
Cdd:COG1506    62 YGEsaGDWGGDEVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYgttREY 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 688 SETHHGVKEEISEkgdttfAYKIATNPEIVKQLKGHLMLVHGDIDNNVHPGNTIRVVNALIRANKRFDMLILPGQRHGF- 766
Cdd:COG1506   141 TERLMGGPWEDPE------AYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFs 214

                         250       260
                  ....*....|....*....|
gi 1052974471 767 GDMDEYFYWRMVDFFSKYLK 786
Cdd:COG1506   215 GAGAPDYLERILDFLDRHLK 234
DPPIV_N super family cl37636
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 138-495 1.75e-44

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


The actual alignment was detected with superfamily member pfam00930:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 164.03  E-value: 1.75e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 138 YFSYDYPTQKLTYLKDKEKEpeeVNWASVSPDGQRVIYAKDCDLYYmsiadyrkarknEKDSTIVEVRLTSDGTPDFGYG 217
Cdd:pfam00930  25 YYIYDLETNRVEPLPPGEGK---IQDAKWSPDGDRLAFVRDNNLYV------------RELATGKEIQITSDGSDGIFNG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 218 IPYSTLNTDTLcnGKRRGAWgyWSPDSKYFATIIADQRNVkPLWVINSIA--EPRPTLETYKYEMPGETGmPEYHLYLFD 295
Cdd:pfam00930  90 VADWVYEEEVL--GSNSAVW--WSPDGSRLAFLRFDESEV-PIITLPYYTdeGPGPEVREIKYPKAGAPN-PTVELFVYD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 296 VQAGTRKEIRTaawknqsidlegkPLEQKQRDkELIPRI-WQGDNqRFFLTRSSRDLHRIDVCTYTLGEDSIVPVVKERM 374
Cdd:pfam00930 164 LASGKTVEVVP-------------PDDLSDAD-YYITRVkWVPDG-KLLVQWLNRDQNRLKVVLCDAETGRTVVILEETS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 375 NTY----QETRPIHvlNGGKEFIQWSERDGWAHLYLYDDKGNLKNRITEGPWHVERVVKVDEATRTVYFVANgrekGENP 450
Cdd:pfam00930 229 DGWvelhQDPHFIK--RDGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTAT----EDSP 302

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1052974471 451 YYEHFYKVNVNGSG-LKQLTHGEFFH--DVEMDDEARFFVDNYSRANT 495
Cdd:pfam00930 303 TERHLYSVSLDSGGePTCLTDDSGDHdySASFSPNGSYYVLTYSGPDT 350
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
533-786 1.02e-53

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 185.61  E-value: 1.02e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 533 VKAADGVTdLYGIMYKPFDfdsTKVYPIIDYVYPGPQveAVDYPFRRMSvrtDRLAQAGFIVITVGQRGghpsrskwyhn 612
Cdd:COG1506     2 FKSADGTT-LPGWLYLPAD---GKKYPVVVYVHGGPG--SRDDSFLPLA---QALASRGYAVLAPDYRG----------- 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 613 YGY--GNMRDYPLADHKAAVEQLAARyPFIDITRVGIHGHSGGGFMSTAAICQYPDFYKAAVSCAGNHDNRIYN---RWW 687
Cdd:COG1506    62 YGEsaGDWGGDEVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYgttREY 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 688 SETHHGVKEEISEkgdttfAYKIATNPEIVKQLKGHLMLVHGDIDNNVHPGNTIRVVNALIRANKRFDMLILPGQRHGF- 766
Cdd:COG1506   141 TERLMGGPWEDPE------AYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFs 214

                         250       260
                  ....*....|....*....|
gi 1052974471 767 GDMDEYFYWRMVDFFSKYLK 786
Cdd:COG1506   215 GAGAPDYLERILDFLDRHLK 234
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 138-495 1.75e-44

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 164.03  E-value: 1.75e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 138 YFSYDYPTQKLTYLKDKEKEpeeVNWASVSPDGQRVIYAKDCDLYYmsiadyrkarknEKDSTIVEVRLTSDGTPDFGYG 217
Cdd:pfam00930  25 YYIYDLETNRVEPLPPGEGK---IQDAKWSPDGDRLAFVRDNNLYV------------RELATGKEIQITSDGSDGIFNG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 218 IPYSTLNTDTLcnGKRRGAWgyWSPDSKYFATIIADQRNVkPLWVINSIA--EPRPTLETYKYEMPGETGmPEYHLYLFD 295
Cdd:pfam00930  90 VADWVYEEEVL--GSNSAVW--WSPDGSRLAFLRFDESEV-PIITLPYYTdeGPGPEVREIKYPKAGAPN-PTVELFVYD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 296 VQAGTRKEIRTaawknqsidlegkPLEQKQRDkELIPRI-WQGDNqRFFLTRSSRDLHRIDVCTYTLGEDSIVPVVKERM 374
Cdd:pfam00930 164 LASGKTVEVVP-------------PDDLSDAD-YYITRVkWVPDG-KLLVQWLNRDQNRLKVVLCDAETGRTVVILEETS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 375 NTY----QETRPIHvlNGGKEFIQWSERDGWAHLYLYDDKGNLKNRITEGPWHVERVVKVDEATRTVYFVANgrekGENP 450
Cdd:pfam00930 229 DGWvelhQDPHFIK--RDGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTAT----EDSP 302

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1052974471 451 YYEHFYKVNVNGSG-LKQLTHGEFFH--DVEMDDEARFFVDNYSRANT 495
Cdd:pfam00930 303 TERHLYSVSLDSGGePTCLTDDSGDHdySASFSPNGSYYVLTYSGPDT 350
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
587-787 2.33e-39

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 144.68  E-value: 2.33e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 587 LAQAGFIVITVGQRGGHPSRSKWYHNyGYGNMRDYPLADHKAAVEQLAARYpFIDITRVGIHGHSGGGFMSTAAICQYPD 666
Cdd:pfam00326  10 LADRGYVVAIANGRGSGGYGEAFHDA-GKGDLGQNEFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAALNQRPD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 667 FYKAAVSCAGNHDNRiynRWWSETHHGVKEEISEKGDTT-----FAYKIATNPEIVKQLKGHLMLVHGDIDNNVHPGNTI 741
Cdd:pfam00326  88 LFKAAVAHVPVVDWL---AYMSDTSLPFTERYMEWGNPWdneegYDYLSPYSPADNVKVYPPLLLIHGLLDDRVPPWQSL 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1052974471 742 RVVNALIRANKRFDMLILPGQRHGFG--DMDEYFYWRMVDFFSKYLKG 787
Cdd:pfam00326 165 KLVAALQRKGVPFLLLIFPDEGHGIGkpRNKVEEYARELAFLLEYLGG 212
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
533-786 1.02e-53

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 185.61  E-value: 1.02e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 533 VKAADGVTdLYGIMYKPFDfdsTKVYPIIDYVYPGPQveAVDYPFRRMSvrtDRLAQAGFIVITVGQRGghpsrskwyhn 612
Cdd:COG1506     2 FKSADGTT-LPGWLYLPAD---GKKYPVVVYVHGGPG--SRDDSFLPLA---QALASRGYAVLAPDYRG----------- 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 613 YGY--GNMRDYPLADHKAAVEQLAARyPFIDITRVGIHGHSGGGFMSTAAICQYPDFYKAAVSCAGNHDNRIYN---RWW 687
Cdd:COG1506    62 YGEsaGDWGGDEVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYgttREY 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 688 SETHHGVKEEISEkgdttfAYKIATNPEIVKQLKGHLMLVHGDIDNNVHPGNTIRVVNALIRANKRFDMLILPGQRHGF- 766
Cdd:COG1506   141 TERLMGGPWEDPE------AYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFs 214

                         250       260
                  ....*....|....*....|
gi 1052974471 767 GDMDEYFYWRMVDFFSKYLK 786
Cdd:COG1506   215 GAGAPDYLERILDFLDRHLK 234
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 138-495 1.75e-44

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 164.03  E-value: 1.75e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 138 YFSYDYPTQKLTYLKDKEKEpeeVNWASVSPDGQRVIYAKDCDLYYmsiadyrkarknEKDSTIVEVRLTSDGTPDFGYG 217
Cdd:pfam00930  25 YYIYDLETNRVEPLPPGEGK---IQDAKWSPDGDRLAFVRDNNLYV------------RELATGKEIQITSDGSDGIFNG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 218 IPYSTLNTDTLcnGKRRGAWgyWSPDSKYFATIIADQRNVkPLWVINSIA--EPRPTLETYKYEMPGETGmPEYHLYLFD 295
Cdd:pfam00930  90 VADWVYEEEVL--GSNSAVW--WSPDGSRLAFLRFDESEV-PIITLPYYTdeGPGPEVREIKYPKAGAPN-PTVELFVYD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 296 VQAGTRKEIRTaawknqsidlegkPLEQKQRDkELIPRI-WQGDNqRFFLTRSSRDLHRIDVCTYTLGEDSIVPVVKERM 374
Cdd:pfam00930 164 LASGKTVEVVP-------------PDDLSDAD-YYITRVkWVPDG-KLLVQWLNRDQNRLKVVLCDAETGRTVVILEETS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 375 NTY----QETRPIHvlNGGKEFIQWSERDGWAHLYLYDDKGNLKNRITEGPWHVERVVKVDEATRTVYFVANgrekGENP 450
Cdd:pfam00930 229 DGWvelhQDPHFIK--RDGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTAT----EDSP 302

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1052974471 451 YYEHFYKVNVNGSG-LKQLTHGEFFH--DVEMDDEARFFVDNYSRANT 495
Cdd:pfam00930 303 TERHLYSVSLDSGGePTCLTDDSGDHdySASFSPNGSYYVLTYSGPDT 350
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
587-787 2.33e-39

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 144.68  E-value: 2.33e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 587 LAQAGFIVITVGQRGGHPSRSKWYHNyGYGNMRDYPLADHKAAVEQLAARYpFIDITRVGIHGHSGGGFMSTAAICQYPD 666
Cdd:pfam00326  10 LADRGYVVAIANGRGSGGYGEAFHDA-GKGDLGQNEFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAALNQRPD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 667 FYKAAVSCAGNHDNRiynRWWSETHHGVKEEISEKGDTT-----FAYKIATNPEIVKQLKGHLMLVHGDIDNNVHPGNTI 741
Cdd:pfam00326  88 LFKAAVAHVPVVDWL---AYMSDTSLPFTERYMEWGNPWdneegYDYLSPYSPADNVKVYPPLLLIHGLLDDRVPPWQSL 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1052974471 742 RVVNALIRANKRFDMLILPGQRHGFG--DMDEYFYWRMVDFFSKYLKG 787
Cdd:pfam00326 165 KLVAALQRKGVPFLLLIFPDEGHGIGkpRNKVEEYARELAFLLEYLGG 212
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
583-781 1.45e-15

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 76.54  E-value: 1.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 583 RTDRLAQAGFIVITV-----GQRGGHPSRSKWYHNygyGNMRDYPLADHKAAVEQLAARyPFIDITRVGIHGHSGGGFMS 657
Cdd:COG0412    48 VARRLAAAGYVVLAPdlygrGGPGDDPDEARALMG---ALDPELLAADLRAALDWLKAQ-PEVDAGRVGVVGFCFGGGLA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 658 TAAICQYPDFyKAAVSCAGNHDNriynrwwsethhgvkeeisekgdttfaykiATNPEIVKQLKGHLMLVHGDIDNNVHP 737
Cdd:COG0412   124 LLAAARGPDL-AAAVSFYGGLPA------------------------------DDLLDLAARIKAPVLLLYGEKDPLVPP 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1052974471 738 GNTIRVVNALIRANKRFDMLILPGQRHGFGDMDEYFY--------W-RMVDFF 781
Cdd:COG0412   173 EQVAALEAALAAAGVDVELHVYPGAGHGFTNPGRPRYdpaaaedaWqRTLAFL 225
COG4099 COG4099
Predicted peptidase [General function prediction only];
535-765 7.05e-12

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 66.14  E-value: 7.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 535 AADGVTDLYGImYKPFDFDSTKVYPIIdyVY------PGPQVEAV-DYPFRRMsVRTDRLAQAGFIVItVGQRgghPSRS 607
Cdd:COG4099    27 PSDGDTLPYRL-YLPKGYDPGKKYPLV--LFlhgageRGTDNEKQlTHGAPKF-INPENQAKFPAIVL-APQC---PEDD 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 608 KWyhnygygnMRDYPLADHKAAVEQLAARYPfIDITRVGIHGHSGGGFMSTAAICQYPDFYKAAVSCAGnhdnriynrww 687
Cdd:COG4099    99 YW--------SDTKALDAVLALLDDLIAEYR-IDPDRIYLTGLSMGGYGTWDLAARYPDLFAAAVPICG----------- 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1052974471 688 sethhgvkeeisekgdttfaykiATNPEIVKQLKG-HLMLVHGDIDNNVHPGNTIRVVNALIRANKRFDMLILPGQRHG 765
Cdd:COG4099   159 -----------------------GGDPANAANLKKvPVWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHN 214
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 529-785 1.35e-11

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 65.32  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 529 EPFKVKAADGVTdLYGIMYKPFDfdSTKVYPIIDYVYPGPQVEAvdypfrRMSVRTDRLAQAGFIVITV-----GQRGGH 603
Cdd:COG1073    11 EDVTFKSRDGIK-LAGDLYLPAG--ASKKYPAVVVAHGNGGVKE------QRALYAQRLAELGFNVLAFdyrgyGESEGE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 604 PSrskwyhnygygNMRDYPLADHKAAVEQLAARyPFIDITRVGIHGHS-GGGFMSTAAIcQYPDFyKAAVSCAGnhdnri 682
Cdd:COG1073    82 PR-----------EEGSPERRDARAAVDYLRTL-PGVDPERIGLLGISlGGGYALNAAA-TDPRV-KAVILDSP------ 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 683 YNRWWSETHHGVKEEISEKGDTTFAYKIATNPEI----------VKQLKGHLMLVHGDIDNNVHPGNTIRVVNAlIRANK 752
Cdd:COG1073   142 FTSLEDLAAQRAKEARGAYLPGVPYLPNVRLASLlndefdplakIEKISRPLLFIHGEKDEAVPFYMSEDLYEA-AAEPK 220

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1052974471 753 RFdmLILPGQRHGFG-DMDEYFYW-RMVDFFSKYL 785
Cdd:COG1073   221 EL--LIVPGAGHVDLyDRPEEEYFdKLAEFFKKNL 253
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 577-676 6.26e-10

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 60.79  E-value: 6.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 577 FRRMSvRTDRLA-QAGFIVITVGQRGGHPSRSkWyhNYGYGNMRDYPLADH---KAAVEQLAARYPfIDITRVGIHGHSG 652
Cdd:COG3509    69 FAAGT-GLNALAdREGFIVVYPEGTGRAPGRC-W--NWFDGRDQRRGRDDVafiAALVDDLAARYG-IDPKRVYVTGLSA 143

                          90       100
                  ....*....|....*....|....
gi 1052974471 653 GGFMSTAAICQYPDFYKAAVSCAG 676
Cdd:COG3509   144 GGAMAYRLACEYPDVFAAVAPVAG 167
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
585-783 1.77e-09

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 58.47  E-value: 1.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 585 DRLAQAGFIVITVGQRG-GHPSRSKWYHNygygNMRDYpLADHKAAVEQLAARYPfidiTRVGIHGHSGGGFMSTAAICQ 663
Cdd:COG2267    49 EALAAAGYAVLAFDLRGhGRSDGPRGHVD----SFDDY-VDDLRAALDALRARPG----LPVVLLGHSMGGLIALLYAAR 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 664 YPDFYKAAVSCAGNHDNR----IYNRWWSETHHgvkeeisekgdttfaykiatnPEIVKQLKGHLMLVHGDIDNNVHPGN 739
Cdd:COG2267   120 YPDRVAGLVLLAPAYRADpllgPSARWLRALRL---------------------AEALARIDVPVLVLHGGADRVVPPEA 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1052974471 740 TIRVVNALiraNKRFDMLILPGQRHG--FGDMDEYFYWRMVDFFSK 783
Cdd:COG2267   179 ARRLAARL---SPDVELVLLPGARHEllNEPAREEVLAAILAWLER 221
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 584-760 1.76e-06

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 49.91  E-value: 1.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 584 TDRLAQAGFIVITVGQRG-----GHPSRSKwyhnygygNMRDYpLADHKAAVEQLAARYPFIDITrvgIHGHSGGGFMST 658
Cdd:pfam12146  24 ADALAAQGFAVYAYDHRGhgrsdGKRGHVP--------SFDDY-VDDLDTFVDKIREEHPGLPLF---LLGHSMGGLIAA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 659 AAICQYPDFYKAAVSCAGNHDNRIYN-RWWSE------THHGVKEEISEKGDTTFAYKiatNPEIVKQLKGhlmlvhgdi 731
Cdd:pfam12146  92 LYALRYPDKVDGLILSAPALKIKPYLaPPILKllakllGKLFPRLRVPNNLLPDSLSR---DPEVVAAYAA--------- 159

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1052974471 732 DNNVHPGNTIRVVNALIRA----NKRFDMLILP 760
Cdd:pfam12146 160 DPLVHGGISARTLYELLDAgerlLRRAAAITVP 192
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 587-687 2.63e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 49.43  E-value: 2.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 587 LAQAGFIVITVGQRG-GHPSRSKWYHNYGYGNMRDyplaDHKAAVEQLaarypfiDITRVGIHGHSGGGFMSTAAICQYP 665
Cdd:pfam00561  23 LARDGFRVIALDLRGfGKSSRPKAQDDYRTDDLAE----DLEYILEAL-------GLEKVNLVGHSMGGLIALAYAAKYP 91

                          90       100
                  ....*....|....*....|..
gi 1052974471 666 DFYKAAVSCAGNHDNRIYNRWW 687
Cdd:pfam00561  92 DRVKALVLLGALDPPHELDEAD 113
YpfH COG0400
Predicted esterase [General function prediction only];
585-676 1.90e-04

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 43.36  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 585 DRLAQAGFIVITVG--QRGGHPSRSkWYHNYGYGNMRDYPLADH-----KAAVEQLAARYPfIDITRVGIHGHSGGGFMS 657
Cdd:COG0400    26 PELALPGAAVLAPRapVPEGPGGRA-WFDLSFLEGREDEEGLAAaaealAAFIDELEARYG-IDPERIVLAGFSQGAAMA 103

                          90
                  ....*....|....*....
gi 1052974471 658 TAAICQYPDFYKAAVSCAG 676
Cdd:COG0400   104 LSLALRRPELLAGVVALSG 122
DLH pfam01738
Dienelactone hydrolase family;
584-766 3.60e-03

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 39.64  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 584 TDRLAQAGFIVIT--VGQRGGHPSRSKWYHNYGYGNMRDYP----LADHKAAVEQLAARyPFIDITRVGIHGHSGGGFMS 657
Cdd:pfam01738  32 ADRLADEGYVALApdLYFRQGDPNDEADAARAMFELVSKRVmekvLDDLEAAVNYLKSQ-PEVSPKKVGVVGYCMGGALA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 658 TAAIcQYPDFYKAAVScagnhdnriynrwwsetHHGVKEEISEkgdttfaykiatnpEIVKQLKGHLMLVHGDIDNNVHP 737
Cdd:pfam01738 111 VLLA-AKGPLVDAAVG-----------------FYGVGPEPPL--------------IEAPDIKAPILFHFGEEDHFVPA 158

                         170       180
                  ....*....|....*....|....*....
gi 1052974471 738 GNTIRVVNALIRANKRFDMLILPGQRHGF 766
Cdd:pfam01738 159 DSRELIEEALKAANVDHQIHSYPGAGHAF 187
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 585-764 4.55e-03

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 39.21  E-value: 4.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 585 DRLAqAGFIVITVGQRG-GHPSRSKwyhnygygnmRDYPLADHKAAVEQLAARypfIDITRVGIHGHSGGGFMSTAAICQ 663
Cdd:COG0596    44 PALA-AGYRVIAPDLRGhGRSDKPA----------GGYTLDDLADDLAALLDA---LGLERVVLVGHSMGGMVALELAAR 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1052974471 664 YPDFYKAAVSCAGNHDNRI-YNRWWSETHHGVKEEISEKGDTTFaykiatnPEIVKQLKGHLMLVHGDIDNNVHPgntiR 742
Cdd:COG0596   110 HPERVAGLVLVDEVLAALAePLRRPGLAPEALAALLRALARTDL-------RERLARITVPTLVIWGEKDPIVPP----A 178

                         170       180
                  ....*....|....*....|..
gi 1052974471 743 VVNALIRANKRFDMLILPGQRH 764
Cdd:COG0596   179 LARRLAELLPNAELVVLPGAGH 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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