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Conserved domains on  [gi|1029308990|emb|SBB08835|]
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Competence transcription factor [Staphylococcus aureus]

Protein Classification

competence protein ComK( domain architecture ID 10008924)

competence protein ComK functions as a master regulator required for the expression of late competence genes including comC, comE, comG, and the bdbDC operon

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ComK COG4903
Competence transcription factor ComK [Transcription];
1-164 3.37e-59

Competence transcription factor ComK [Transcription];


:

Pssm-ID: 443931  Cd Length: 171  Bit Score: 182.47  E-value: 3.37e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990   1 MYSQNIYVIRKGDMVIRPAFDDDDQrnGSEIIRFDKTRIqNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL 80
Cdd:COG4903     3 LEYLESYIINESTMALLPYFEDGKY--GTRVIEKDGEYY-VPQKPLKIIDRSCKYYGSSYEGRKEAAKHILGITHKPPIV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990  81 LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS 160
Cdd:COG4903    80 IDPLLGIYFFPTHSPRSPECIWISLSHIDRIEEAKDGKTIITFKNGKSIELPISYSSFENQYQRTAQLRYRLNKRIRQLQ 159


                  ....
gi 1029308990 161 KNPD 164
Cdd:COG4903   160 KKLE 163
 
Name Accession Description Interval E-value
ComK COG4903
Competence transcription factor ComK [Transcription];
1-164 3.37e-59

Competence transcription factor ComK [Transcription];


Pssm-ID: 443931  Cd Length: 171  Bit Score: 182.47  E-value: 3.37e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990   1 MYSQNIYVIRKGDMVIRPAFDDDDQrnGSEIIRFDKTRIqNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL 80
Cdd:COG4903     3 LEYLESYIINESTMALLPYFEDGKY--GTRVIEKDGEYY-VPQKPLKIIDRSCKYYGSSYEGRKEAAKHILGITHKPPIV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990  81 LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS 160
Cdd:COG4903    80 IDPLLGIYFFPTHSPRSPECIWISLSHIDRIEEAKDGKTIITFKNGKSIELPISYSSFENQYQRTAQLRYRLNKRIRQLQ 159


                  ....
gi 1029308990 161 KNPD 164
Cdd:COG4903   160 KKLE 163
ComK pfam06338
ComK protein; This family consists of several bacterial ComK proteins. The ComK protein of ...
 6-157 7.72e-59

ComK protein; This family consists of several bacterial ComK proteins. The ComK protein of Bacillus subtilis positively regulates the transcription of several late competence genes as well as comK itself. It has been found that ClpX plays an important role in the regulation of ComK at the post-transcriptional level.


Pssm-ID: 428894  Cd Length: 152  Bit Score: 180.93  E-value: 7.72e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990   6 IYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIqnPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLF 85
Cdd:pfam06338   3 KYEINPSTMAILPKFDIDGKLYSKVIEEEDEFYV--PQKPLQIIEKSCRYYGSSYEGRKEGTKEVTGITHKPPIVIDPTN 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1029308990  86 PTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSR 157
Cdd:pfam06338  81 NIYFFPTKSPSRPDCIWISHSHIEDVKELKYKKTIVLFKNGHTLTLDISPKSFENQLYRTAQLRYKLQQRIK 152
 
Name Accession Description Interval E-value
ComK COG4903
Competence transcription factor ComK [Transcription];
1-164 3.37e-59

Competence transcription factor ComK [Transcription];


Pssm-ID: 443931  Cd Length: 171  Bit Score: 182.47  E-value: 3.37e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990   1 MYSQNIYVIRKGDMVIRPAFDDDDQrnGSEIIRFDKTRIqNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL 80
Cdd:COG4903     3 LEYLESYIINESTMALLPYFEDGKY--GTRVIEKDGEYY-VPQKPLKIIDRSCKYYGSSYEGRKEAAKHILGITHKPPIV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990  81 LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS 160
Cdd:COG4903    80 IDPLLGIYFFPTHSPRSPECIWISLSHIDRIEEAKDGKTIITFKNGKSIELPISYSSFENQYQRTAQLRYRLNKRIRQLQ 159


                  ....
gi 1029308990 161 KNPD 164
Cdd:COG4903   160 KKLE 163
ComK pfam06338
ComK protein; This family consists of several bacterial ComK proteins. The ComK protein of ...
 6-157 7.72e-59

ComK protein; This family consists of several bacterial ComK proteins. The ComK protein of Bacillus subtilis positively regulates the transcription of several late competence genes as well as comK itself. It has been found that ClpX plays an important role in the regulation of ComK at the post-transcriptional level.


Pssm-ID: 428894  Cd Length: 152  Bit Score: 180.93  E-value: 7.72e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1029308990   6 IYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIqnPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLF 85
Cdd:pfam06338   3 KYEINPSTMAILPKFDIDGKLYSKVIEEEDEFYV--PQKPLQIIEKSCRYYGSSYEGRKEGTKEVTGITHKPPIVIDPTN 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1029308990  86 PTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSR 157
Cdd:pfam06338  81 NIYFFPTKSPSRPDCIWISHSHIEDVKELKYKKTIVLFKNGHTLTLDISPKSFENQLYRTAQLRYKLQQRIK 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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