|
Name |
Accession |
Description |
Interval |
E-value |
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
3-291 |
1.32e-120 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 347.81 E-value: 1.32e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 3 AFDLIGNTPLVLLESFS-NKDVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHY 81
Cdd:COG0031 7 ILELIGNTPLVRLNRLSpGPGAEIYAKLESFNPGGSVKDRIALSMIEDAEKRGLLKPGGTIVEATSGNTGIGLAMVAAAK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 82 GVSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARdyELQ---TGAYYLNQFESYRNPETYKSTIGKEITD 158
Cdd:COG0031 87 GYRLILVMPETMSKERRALLRAYGAEVVLTPGAEGMKGAIDKAE--ELAaetPGAFWPNQFENPANPEAHYETTGPEIWE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 159 KLK-DIDYFVGGVGSGGTFAGVAEHL-AASYRTESVIVEPEGS-ILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVS 235
Cdd:COG0031 165 QTDgKVDAFVAGVGTGGTITGVGRYLkERNPDIKIVAVEPEGSpLLSGGEPGPHKIEGIGAGFVPKILDPSLIDEVITVS 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1564862654 236 DDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKG-VIVTIFPDGSDRYMSK 291
Cdd:COG0031 245 DEEAFAMARRLAREEGILVGISSGAAVAAALRLAKRLGPGkTIVTILPDSGERYLST 301
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
8-290 |
1.24e-113 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 329.86 E-value: 1.24e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFSN-KDVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGVSAV 86
Cdd:cd01561 1 GNTPLVRLNRLSPgTGAEIYAKLEFFNPGGSVKDRIALYMIEDAEKRGLLKPGTTIIEPTSGNTGIGLAMVAAAKGYRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 87 IFAPEGFSEEKISIIKALGAEVIRTD--QTLGMAGAQKAARDYELQT-GAYYLNQFESYRNPETYKSTIGKEITDKLKD- 162
Cdd:cd01561 81 IVMPETMSEEKRKLLRALGAEVILTPeaEADGMKGAIAKARELAAETpNAFWLNQFENPANPEAHYETTAPEIWEQLDGk 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 IDYFVGGVGSGGTFAGVAEHL-AASYRTESVIVEPEGSIL-SGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDAAF 240
Cdd:cd01561 161 VDAFVAGVGTGGTITGVARYLkEKNPNVRIVGVDPVGSVLfSGGPPGPHKIEGIGAGFIPENLDRSLIDEVVRVSDEEAF 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1564862654 241 QNVKLLARQEGLLVGSSSGAALQGALEIKKHINKG-VIVTIFPDGSDRYMS 290
Cdd:cd01561 241 AMARRLAREEGLLVGGSSGAAVAAALKLAKRLGPGkTIVTILPDSGERYLS 291
|
|
| cysK |
TIGR01139 |
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine ... |
5-290 |
1.99e-87 |
|
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273465 Cd Length: 298 Bit Score: 263.46 E-value: 1.99e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNKDVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGVS 84
Cdd:TIGR01139 3 ELIGNTPLVRLNRIEGCNANVFVKLEGRNPSGSVKDRIALNMIWDAEKRGLLKPGKTIVEPTSGNTGIALAMVAAARGYK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 85 AVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAYY--LNQFESYRNPETYKSTIGKEI-TDKLK 161
Cdd:TIGR01139 83 LILTMPETMSIERRKLLKAYGAELVLTPGAEGMKGAIAKAEEIAASTPNSYfmLQQFENPANPEIHRKTTGPEIwRDTDG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 162 DIDYFVGGVGSGGTFAGVAEHLAASY-RTESVIVEPEGS-ILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDAA 239
Cdd:TIGR01139 163 KLDAFVAGVGTGGTITGVGEVLKEQKpNIKIVAVEPAESpVLSGGKPGPHKIQGIGAGFIPKNLNRSVIDEVITVSDEEA 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1564862654 240 FQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKG-VIVTIFPDGSDRYMS 290
Cdd:TIGR01139 243 IETARRLAAEEGILVGISSGAAVAAALKLAKRPEPDkLIVVILPSTGERYLS 294
|
|
| cysKM |
TIGR01136 |
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and ... |
5-290 |
1.20e-81 |
|
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273463 Cd Length: 299 Bit Score: 248.74 E-value: 1.20e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:TIGR01136 3 ELIGNTPLVRLNRLAPGcDARVLAKLEGFNPSGSVKDRIALSMILDAEKRGLLKPGDTIIEATSGNTGIALAMVAAARGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAY-YLNQFESYRNPETYKSTIGKEITDKLK- 161
Cdd:TIGR01136 83 KLILTMPETMSLERRKLLRAYGAELILTPGEEGMKGAIDKAEELAAETNKYvMLDQFENPANPEAHYKTTGPEIWRDTDg 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 162 DIDYFVGGVGSGGTFAGVAEHLAASY-RTESVIVEP-EGSILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDAA 239
Cdd:TIGR01136 163 RIDHFVAGVGTGGTITGVGRYLKEQNpNIQIVAVEPaESPVLSGGEPGPHKIQGIGAGFIPKILDLSLIDEVITVSDEDA 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1564862654 240 FQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKG--VIVTIFPDGSDRYMS 290
Cdd:TIGR01136 243 IETARRLAREEGILVGISSGAAVAAALKLAKRLENAdkVIVAILPDTGERYLS 295
|
|
| cysta_beta |
TIGR01137 |
cystathionine beta-synthase; Members of this family closely resemble cysteine synthase but ... |
5-295 |
5.61e-74 |
|
cystathionine beta-synthase; Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273464 [Multi-domain] Cd Length: 455 Bit Score: 233.92 E-value: 5.61e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSnKDV--QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYG 82
Cdd:TIGR01137 7 DLIGNTPLVRLNKVS-KGLkcELLAKCEFFNPGGSVKDRIALRMIEDAEASGRLKPGDTIIEPTSGNTGIGLALVAAIKG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRT---------DQTLGMagAQKAARDYElqtGAYYLNQFESYRNPETYKSTIG 153
Cdd:TIGR01137 86 YKCIIVLPEKMSSEKVDVLRALGAEIVRTptaaafdspESHIGV--AKRLVREIP---GAHILDQYRNPSNPLAHYDTTG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 154 KEITDKLKD-IDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEPEGSILSGG------NAHSHDIEGIGSEKWPSFLPR 225
Cdd:TIGR01137 161 PEILEQCEGkLDMFVAGVGTGGTITGIARYLKESCPGCRIVgADPEGSILAQPeelnqtGRTPYKVEGIGYDFIPTVLDR 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1564862654 226 ALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINK--GVIVTIFPDGSDRYMSKqILN 295
Cdd:TIGR01137 241 KVVDEWIKTDDKESFTMARRLIKEEGLLVGGSSGSAVVAALKAAEDELQegQRCVVLLPDSIRNYMTK-FLN 311
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
4-283 |
2.89e-69 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 216.79 E-value: 2.89e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 4 FDLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIREniiQKGDVVVEASAGNTGIGVAIAANHYG 82
Cdd:pfam00291 2 SLGIGPTPLVRLPRLSKElGVDVYLKLESLNPTGSFKDRGALNLLLRLKEG---EGGKTVVEASSGNHGRALAAAAARLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAgAQKAARDYELQTGAYYLNQFESYRNPETYKsTIGKEITDKL-K 161
Cdd:pfam00291 79 LKVTIVVPEDAPPGKLLLMRALGAEVVLVGGDYDEA-VAAARELAAEGPGAYYINQYDNPLNIEGYG-TIGLEILEQLgG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 162 DIDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEPEGSILSGGNAH----------SHDIEGIGSEKWPSFLP----RA 226
Cdd:pfam00291 157 DPDAVVVPVGGGGLIAGIARGLKELGPDVRVIgVEPEGAPALARSLAagrpvpvpvaDTIADGLGVGDEPGALAldllDE 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1564862654 227 LVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGA-LEIKKHINKG-VIVTIFPD 283
Cdd:pfam00291 237 YVGEVVTVSDEEALEAMRLLARREGIVVEPSSAAALAALkLALAGELKGGdRVVVVLTG 295
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
5-291 |
5.12e-69 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 217.42 E-value: 5.12e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:PRK10717 9 DTIGNTPLIRLNRASEAtGCEILGKAEFLNPGGSVKDRAALNIIWDAEKRGLLKPGGTIVEGTAGNTGIGLALVAAARGY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQT--------LGMAGAQKAARDYELQTGAYYLNQFESYRNPETYKSTIGKE 155
Cdd:PRK10717 89 KTVIVMPETQSQEKKDLLRALGAELVLVPAApyanpnnyVKGAGRLAEELVASEPNGAIWANQFDNPANREAHYETTGPE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 156 I---TDklKDIDYFVGGVGSGGTFAGVAEHL-AASYRTESVIVEPEGS----------ILSGGnahSHDIEGIGSEKWPS 221
Cdd:PRK10717 169 IweqTD--GKVDGFVCAVGTGGTLAGVSRYLkETNPKVKIVLADPTGSalysyyktgeLKAEG---SSITEGIGQGRITA 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1564862654 222 FLPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKG-VIVTIFPDGSDRYMSK 291
Cdd:PRK10717 244 NLEGAPIDDAIRIPDEEALSTAYRLLEEEGLCLGGSSGINVAAALRLARELGPGhTIVTILCDSGERYQSK 314
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
10-284 |
4.61e-65 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 204.29 E-value: 4.61e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGdVVVEASAGNTGIGVAIAANHYGVSAVIF 88
Cdd:cd00640 1 TPLVRLKRLSKLgGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLPKG-VIIESTGGNTGIALAAAAARLGLKCTIV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 89 APEGFSEEKISIIKALGAEVIRTDQTLGmaGAQKAARDY-ELQTGAYYLNQFESYRNPETYKsTIGKEITDKLKD--IDY 165
Cdd:cd00640 80 MPEGASPEKVAQMRALGAEVVLVPGDFD--DAIALAKELaEEDPGAYYVNQFDNPANIAGQG-TIGLEILEQLGGqkPDA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 166 FVGGVGSGGTFAGVAEHLAASY-RTESVIVEPEgsilsggnahshdiegigsekwpsflpralvsdIIKVSDDAAFQNVK 244
Cdd:cd00640 157 VVVPVGGGGNIAGIARALKELLpNVKVIGVEPE---------------------------------VVTVSDEEALEAIR 203
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1564862654 245 LLARQEGLLVGSSSGAALQGALEIKKHINKG-VIVTIFPDG 284
Cdd:cd00640 204 LLAREEGILVEPSSAAALAAALKLAKKLGKGkTVVVILTGG 244
|
|
| cysM |
TIGR01138 |
cysteine synthase B; CysM differs from CysK in that it can also use thiosulfate instead of ... |
5-290 |
9.81e-62 |
|
cysteine synthase B; CysM differs from CysK in that it can also use thiosulfate instead of sulfide, to produce cysteine thiosulfonate instead of cysteine. Alternate name: O-acetylserine (thiol)-lyase [Amino acid biosynthesis, Serine family]
Pssm-ID: 130208 [Multi-domain] Cd Length: 290 Bit Score: 197.44 E-value: 9.81e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESF-SNKDVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:TIGR01138 4 QTVGNTPLVRLQRMgPENGSEVWLKLEGNNPAGSVKDRPALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAYYLNQFESYRNPETYKSTIGKEITDKLK-D 162
Cdd:TIGR01138 84 RMKLLMPDNMSQERKAAMRAYGAELILVTKEEGMEGARDLALELANRGEGKLLDQFNNPDNPYAHYTSTGPEIWQQTGgR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 IDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEP-EGSILSGgnahshdIEGIGSEKWPSFLPRALVSDIIKVSDDAAF 240
Cdd:TIGR01138 164 ITHFVSSMGTTGTIMGVSRFLKEQNPPVQIVgLQPeEGSSIPG-------IRRWPTEYLPGIFDASLVDRVLDIHQRDAE 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1564862654 241 QNVKLLARQEGLLVGSSSGAALQGALEIKKHINKGVIVTIFPDGSDRYMS 290
Cdd:TIGR01138 237 NTMRELAVREGIFCGVSSGGAVAAALRLARELPDAVVVAIICDRGDRYLS 286
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
5-295 |
1.37e-61 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 198.30 E-value: 1.37e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNKDV-QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKG-DVVVEASAGNTGIGVAIAANHYG 82
Cdd:PLN00011 13 ELIGNTPMVYLNNIVDGCVaRIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGkSTLIEATAGNTGIGLACIGAARG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQT-GAYYLNQFESYRNPETYKSTIGKEI-TDKL 160
Cdd:PLN00011 93 YKVILVMPSTMSLERRIILRALGAEVHLTDQSIGLKGMLEKAEEILSKTpGGYIPQQFENPANPEIHYRTTGPEIwRDSA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 161 KDIDYFVGGVGSGGTFAGVAEHLAASYRTESV-IVEP-EGSILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDA 238
Cdd:PLN00011 173 GKVDILVAGVGTGGTATGVGKFLKEKNKDIKVcVVEPvESAVLSGGQPGPHLIQGIGSGIIPFNLDLTIVDEIIQVTGEE 252
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1564862654 239 AFQNVKLLARQEGLLVGSSSGAALQGALEI-KKHINKG-VIVTIFPDGSDRYMSKQILN 295
Cdd:PLN00011 253 AIETAKLLALKEGLLVGISSGAAAAAALKVaKRPENAGkLIVVIFPSGGERYLSTKLFE 311
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
5-290 |
6.69e-61 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 196.30 E-value: 6.69e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNKDV-QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGD-VVVEASAGNTGIGVAIAANHYG 82
Cdd:PLN02565 11 ELIGKTPLVYLNNVVDGCVaRIAAKLEMMEPCSSVKDRIGYSMITDAEEKGLIKPGEsVLIEPTSGNTGIGLAFMAAAKG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQT-GAYYLNQFESYRNPETYKSTIGKEI-TDKL 160
Cdd:PLN02565 91 YKLIITMPASMSLERRIILLAFGAELVLTDPAKGMKGAVQKAEEILAKTpNSYILQQFENPANPKIHYETTGPEIwKGTG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 161 KDIDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEP-EGSILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDA 238
Cdd:PLN02565 171 GKVDAFVSGIGTGGTITGAGKYLKEQNPDIKLYgVEPvESAVLSGGKPGPHKIQGIGAGFIPGVLDVDLLDEVVQVSSDE 250
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1564862654 239 AFQNVKLLARQEGLLVGSSSGAALQGALEI-KKHINKG-VIVTIFPDGSDRYMS 290
Cdd:PLN02565 251 AIETAKLLALKEGLLVGISSGAAAAAAIKIaKRPENAGkLIVVIFPSFGERYLS 304
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
5-290 |
7.17e-58 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 187.77 E-value: 7.17e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFS-NKDVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:PRK11761 8 DTIGNTPLVKLQRLPpDRGNTILAKLEGNNPAGSVKDRPALSMIVQAEKRGEIKPGDTLIEATSGNTGIALAMIAAIKGY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAYYLNQFESYRNPETYKSTIGKEI-TDKLKD 162
Cdd:PRK11761 88 RMKLIMPENMSQERRAAMRAYGAELILVPKEQGMEGARDLALQMQAEGEGKVLDQFANPDNPLAHYETTGPEIwRQTEGR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 IDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEP-EGSilsggnahshDIEGIgsEKWPS-FLP----RALVSDIIKVS 235
Cdd:PRK11761 168 ITHFVSSMGTTGTIMGVSRYLKEQNPAVQIVgLQPeEGS----------SIPGI--RRWPEeYLPkifdASRVDRVLDVS 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1564862654 236 DDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKGVIVTIFPDGSDRYMS 290
Cdd:PRK11761 236 QQEAENTMRRLAREEGIFCGVSSGGAVAAALRIARENPNAVIVAIICDRGDRYLS 290
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
6-290 |
1.61e-54 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 183.05 E-value: 1.61e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 6 LIGNTPLVLLESFSNKDV-QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKG-DVVVEASAGNTGIGVAIAANHYGV 83
Cdd:PLN03013 120 LIGKTPMVYLNSIAKGCVaNIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLAFIAASRGY 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGA-QKAARDYELQTGAYYLNQFESYRNPETYKSTIGKEITDKLK- 161
Cdd:PLN03013 200 RLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAvQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKg 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 162 DIDYFVGGVGSGGTFAGVAEHLA-ASYRTESVIVEP-EGSILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDAA 239
Cdd:PLN03013 280 KVDIFVAGIGTGGTITGVGRFIKeKNPKTQVIGVEPtESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEA 359
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1564862654 240 FQNVKLLARQEGLLVGSSSGAALQGALEI-KKHINKG-VIVTIFPDGSdRYMS 290
Cdd:PLN03013 360 IETAKQLALKEGLMVGISSGAAAAAAIKVaKRPENAGkLIAVSLFASG-RDIY 411
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
6-290 |
5.63e-51 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 172.07 E-value: 5.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 6 LIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGD-VVVEASAGNTGIGVAIAANHYGV 83
Cdd:PLN02556 56 LIGKTPLVYLNKVTEGcGAYIAAKQEMFQPTSSIKDRPALAMIEDAEKKNLITPGKtTLIEPTSGNMGISLAFMAAMKGY 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGA-QKAARDYELQTGAYYLNQFESYRNPETYKSTIGKEI-TDKLK 161
Cdd:PLN02556 136 KMILTMPSYTSLERRVTMRAFGAELVLTDPTKGMGGTvKKAYELLESTPDAFMLQQFSNPANTQVHFETTGPEIwEDTLG 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 162 DIDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEP-EGSILSGGNAHSHDIEGIGSEKWPSFLPRALVSDIIKVSDDAA 239
Cdd:PLN02556 216 QVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYgVEPaESNVLNGGKPGPHHITGNGVGFKPDILDMDVMEKVLEVSSEDA 295
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1564862654 240 FQNVKLLARQEGLLVGSSSGAALQGALEI-KKHINKG-VIVTIFPDGSDRYMS 290
Cdd:PLN02556 296 VNMARELALKEGLMVGISSGANTVAALRLaKMPENKGkLIVTVHPSFGERYLS 348
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
10-280 |
8.96e-36 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 130.93 E-value: 8.96e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIeTAIRENIIQKGdvVVEASAGNTGIGVAIAANHYGVSAVIF 88
Cdd:COG1171 25 TPLLRSPTLSERlGAEVYLKLENLQPTGSFKLRGAYNAL-ASLSEEERARG--VVAASAGNHAQGVAYAARLLGIPATIV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 89 APEGFSEEKISIIKALGAEVIRTDQTLgmAGAQKAARDYELQTGAYYLnqfESYRNPET---YkSTIGKEITDKLKDIDY 165
Cdd:COG1171 102 MPETAPAVKVAATRAYGAEVVLHGDTY--DDAEAAAAELAEEEGATFV---HPFDDPDViagQ-GTIALEILEQLPDLDA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 166 FVGGVGSGGTFAGVAEHLAASY-RTESVIVEPEG------SILSGgnaHSHDIEG------------IGSEKWPsfLPRA 226
Cdd:COG1171 176 VFVPVGGGGLIAGVAAALKALSpDIRVIGVEPEGaaamyrSLAAG---EPVTLPGvdtiadglavgrPGELTFE--ILRD 250
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1564862654 227 LVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKGVIVTI 280
Cdd:COG1171 251 LVDDIVTVSEDEIAAAMRLLLERTKIVVEPAGAAALAALLAGKERLKGKRVVVV 304
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
10-278 |
7.05e-33 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 122.60 E-value: 7.05e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIqKGdvVVEASAGNTGIGVAIAANHYGVSAVIF 88
Cdd:cd01562 18 TPLLTSPTLSELlGAEVYLKCENLQKTGSFKIRGAYNKLLSLSEEERA-KG--VVAASAGNHAQGVAYAAKLLGIPATIV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 89 APEGFSEEKISIIKALGAEVIRTDQTlgMAGAQKAARDYELQTGAYYLNQFESyrnPETYK--STIGKEITDKLKDIDYF 166
Cdd:cd01562 95 MPETAPAAKVDATRAYGAEVVLYGED--FDEAEAKARELAEEEGLTFIHPFDD---PDVIAgqGTIGLEILEQVPDLDAV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 167 VGGVGSGGTFAGVAEHLAASYRTESVI-VEPEG------SILSGG----NAHSHDIEGIG----SEKWPSFLpRALVSDI 231
Cdd:cd01562 170 FVPVGGGGLIAGIATAVKALSPNTKVIgVEPEGapamaqSLAAGKpvtlPEVDTIADGLAvkrpGELTFEII-RKLVDDV 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1564862654 232 IKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIK-KHINKGVIV 278
Cdd:cd01562 249 VTVSEDEIAAAMLLLFEREKLVAEPAGALALAALLSGKlDLKGKKVVV 296
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
5-291 |
7.37e-32 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 122.41 E-value: 7.37e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNKD-VQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:PLN02356 49 DAIGNTPLIRINSLSEATgCEILGKCEFLNPGGSVKDRVAVKIIEEALESGQLFPGGVVTEGSAGSTAISLATVAPAYGC 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIRT--------DQTLGMAgAQKAARDYELQ------------------------- 130
Cdd:PLN02356 129 KCHVVIPDDVAIEKSQILEALGATVERVrpvsithkDHYVNIA-RRRALEANELAskrrkgsetdgihlektngciseee 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 131 ----------TGAYYLNQFESYRNPETYKSTIGKEITDKLK-DIDYFVGGVGSGGTFAGVAEHLA-ASYRTESVIVEPEG 198
Cdd:PLN02356 208 kenslfssscTGGFFADQFENLANFRAHYEGTGPEIWEQTQgNLDAFVAAAGTGGTLAGVSRFLQeKNPNIKCFLIDPPG 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 199 SIL----SGGNAHSHD--------------IEGIGSEKWPSFLPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGA 260
Cdd:PLN02356 288 SGLfnkvTRGVMYTREeaegrrlknpfdtiTEGIGINRLTQNFLMAKLDGAFRGTDKEAVEMSRYLLKNDGLFVGSSSAM 367
|
330 340 350
....*....|....*....|....*....|..
gi 1564862654 261 ALQGALEIKKHINKG-VIVTIFPDGSDRYMSK 291
Cdd:PLN02356 368 NCVGAVRVAQSLGPGhTIVTILCDSGMRHLSK 399
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
10-262 |
1.13e-26 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 106.19 E-value: 1.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNKDVQIYAKLEQYNPGGSVKDRLGKHLIETA-IREniiqkgDVVVEASAGNTGIGVAIAANHYGVSAVIF 88
Cdd:PRK08246 24 TPVLEADGAGFGPAPVWLKLEHLQHTGSFKARGAFNRLLAApVPA------AGVVAASGGNAGLAVAYAAAALGVPATVF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 89 APEGFSEEKISIIKALGAEVIRTDQTlgMAGAQKAARDYELQTGAYYLNqfeSYRNPETY--KSTIGKEITDKLKDIDYF 166
Cdd:PRK08246 98 VPETAPPAKVARLRALGAEVVVVGAE--YADALEAAQAFAAETGALLCH---AYDQPEVLagAGTLGLEIEEQAPGVDTV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 167 VGGVGSGGTFAGVAehLAASYRTESVIVEPEGSI---------------LSGGNAHSHDIEGIGSEKWPsfLPRALVSDI 231
Cdd:PRK08246 173 LVAVGGGGLIAGIA--AWFEGRARVVAVEPEGAPtlhaalaagepvdvpVSGIAADSLGARRVGEIAFA--LARAHVVTS 248
|
250 260 270
....*....|....*....|....*....|.
gi 1564862654 232 IKVSDDAAFQNVKLLARQEGLLVGSSSGAAL 262
Cdd:PRK08246 249 VLVSDEAIIAARRALWEELRLAVEPGAATAL 279
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
8-277 |
1.99e-24 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 100.36 E-value: 1.99e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFSNK--DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIiqkgDVVVEASAGNTGIGVAIAANHYGVSA 85
Cdd:cd01563 21 GNTPLVRAPRLGERlgGKNLYVKDEGLNPTGSFKDRGMTVAVSKAKELGV----KAVACASTGNTSASLAAYAARAGIKC 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 86 VIFAPEGFSEEKISIIKALGAEVIRTDQTLGmaGAQKAARDYELQTGAYYLNQFESYRnPETYKsTIGKEITDKLKDI-- 163
Cdd:cd01563 97 VVFLPAGKALGKLAQALAYGATVLAVEGNFD--DALRLVRELAEENWIYLSNSLNPYR-LEGQK-TIAFEIAEQLGWEvp 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 164 DYFVGGVGSGGTFAGV---AEHLAASYRTES----VIVEPEGS--ILSGGNAHSHDIE------------GIGSekwPSF 222
Cdd:cd01563 173 DYVVVPVGNGGNITAIwkgFKELKELGLIDRlprmVGVQAEGAapIVRAFKEGKDDIEpvenpetiataiRIGN---PAS 249
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1564862654 223 LPRALVS------DIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGAleiKKHINKGVI 277
Cdd:cd01563 250 GPKALRAvresggTAVAVSDEEILEAQKLLARTEGIFVEPASAASLAGL---KKLREEGII 307
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
10-270 |
7.08e-24 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 99.00 E-value: 7.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPL---VLLESFSNKDVqiYAKLEQYNPGGSVKDR--LGKHLIETAIREniiQKGdvVVEASAGNTGIGVAIAANHYGVS 84
Cdd:PRK06815 21 TPLehsPLLSQHTGCEV--YLKCEHLQHTGSFKFRgaSNKLRLLNEAQR---QQG--VITASSGNHGQGVALAAKLAGIP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 85 AVIFAPEGFSEEKISIIKALGAEVIRTDQTlgMAGAQKAARDYELQTGAYYLNqfeSYRNPETY--KSTIGKEITDKLKD 162
Cdd:PRK06815 94 VTVYAPEQASAIKLDAIRALGAEVRLYGGD--ALNAELAARRAAEQQGKVYIS---PYNDPQVIagQGTIGMELVEQQPD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 IDYFVGGVGSGGTFAGVAEHLAA-SYRTESVIVEPEGS-------------------ILSGGNAHshdieGI--GSEKWP 220
Cdd:PRK06815 169 LDAVFVAVGGGGLISGIATYLKTlSPKTEIIGCWPANSpslytsleageivevaeqpTLSDGTAG-----GVepGAITFP 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1564862654 221 sfLPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKK 270
Cdd:PRK06815 244 --LCQQLIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALKLAP 291
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
8-277 |
6.92e-21 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 91.41 E-value: 6.92e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDR----LGKHLIETAIReniiqkgdVVVEASAGNTGIGVAIAANHYG 82
Cdd:COG0498 65 GGTPLVKAPRLADElGKNLYVKEEGHNPTGSFKDRamqvAVSLALERGAK--------TIVCASSGNGSAALAAYAARAG 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGF-SEEKISIIKALGAEVIRTDQTLG--MAGAQKAARDYELqtgaYYLNQFESYRnPETYKsTIGKEITDK 159
Cdd:COG0498 137 IEVFVFVPEGKvSPGQLAQMLTYGAHVIAVDGNFDdaQRLVKELAADEGL----YAVNSINPAR-LEGQK-TYAFEIAEQ 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 160 LKDI-DYFVGGVGSGGTFAGV---AEHLAASYRTES----VIVEPEGS--ILSGGNAHSHDIEGIGSE--------KWPS 221
Cdd:COG0498 211 LGRVpDWVVVPTGNGGNILAGykaFKELKELGLIDRlprlIAVQATGCnpILTAFETGRDEYEPERPEtiapsmdiGNPS 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1564862654 222 FLPRALV------SDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGAleiKKHINKGVI 277
Cdd:COG0498 291 NGERALFalresgGTAVAVSDEEILEAIRLLARREGIFVEPATAVAVAGL---RKLREEGEI 349
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
5-198 |
1.96e-19 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 87.55 E-value: 1.96e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 5 DLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIREniiQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:PRK08639 21 DVVPETPLQRNDYLSEKyGANVYLKREDLQPVRSYKLRGAYNAISQLSDE---ELAAGVVCASAGNHAQGVAYACRHLGI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEKISIIKALGAEVIrtdqTLGMAG-----AQKAARDYELQTGAYYLNQFEsyrNPETY--KSTIGKEI 156
Cdd:PRK08639 98 PGVIFMPVTTPQQKIDQVRFFGGEFV----EIVLVGdtfddSAAAAQEYAEETGATFIPPFD---DPDVIagQGTVAVEI 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1564862654 157 ---TDKLKDIDYFVGGVGSGGTFAGVAEHLAA-SYRTESVIVEPEG 198
Cdd:PRK08639 171 leqLEKEGSPDYVFVPVGGGGLISGVTTYLKErSPKTKIIGVEPAG 216
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
24-270 |
2.80e-18 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 83.22 E-value: 2.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 24 QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIiqkgDVVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKA 103
Cdd:PRK06381 32 KIYLKFEGANPTGTQKDRIAEAHVRRAMRLGY----SGITVGTCGNYGASIAYFARLYGLKAVIFIPRSYSNSRVKEMEK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 104 LGAEVIRTDqtlgmaGAQKAA----RDYELQTGAYYLN--QFESYRNPETYkSTIGKEITDKLKDIDYFVG-GVGSGGTF 176
Cdd:PRK06381 108 YGAEIIYVD------GKYEEAversRKFAKENGIYDANpgSVNSVVDIEAY-SAIAYEIYEALGDVPDAVAvPVGNGTTL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 177 AGVAEHLAASYRTESVIVEPE--GSILSGGN----AHSHdiegiGSEK--------------------WPSF-LPRALVS 229
Cdd:PRK06381 181 AGIYHGFRRLYDRGKTSRMPRmiGVSTSGGNqiveSFKR-----GSSEvvdlevdeiretavneplvsYRSFdGDNALEA 255
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1564862654 230 ------DIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKK 270
Cdd:PRK06381 256 iydshgYAFGFSDDEMVKYAELLRRMEGLNALPASASALAALVKYLK 302
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
9-262 |
3.57e-17 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 80.04 E-value: 3.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 9 NTPLvlLESFS---NKDVQIYAKLEQYNPGGSVKDRLGKHLIETAIrENIIQKGDVVVEASAGNTGIGVAIAANHYGVSA 85
Cdd:cd06448 1 KTPL--IESTAlskTAGCNVFLKLENLQPSGSFKIRGIGHLCQKSA-KQGLNECVHVVCSSGGNAGLAAAYAARKLGVPC 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 86 VIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAYYLNQFEsyrNPETYK--STIGKEITDKLKD- 162
Cdd:cd06448 78 TIVVPESTKPRVVEKLRDEGATVVVHGKVWWEADNYLREELAENDPGPVYVHPFD---DPLIWEghSSMVDEIAQQLQSq 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 --IDYFVGGVGSGGTFAGVAEHL--AASYRTESVIVEPEG------SILSGGNAHSHDIEGI---------GSEKWPSFL 223
Cdd:cd06448 155 ekVDAIVCSVGGGGLLNGIVQGLerNGWGDIPVVAVETEGahslnaSLKAGKLVTLPKITSVatslgaktvSSQALEYAQ 234
|
250 260 270
....*....|....*....|....*....|....*....
gi 1564862654 224 PRALVSdiIKVSDDAAFQNVKLLARQEGLLVGSSSGAAL 262
Cdd:cd06448 235 EHNIKS--EVVSDRDAVQACLRFADDERILVEPACGAAL 271
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
10-280 |
6.21e-15 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 73.85 E-value: 6.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIeTAIRENIIQKGdvVVEASAGNTGIGVAIAANHYGVSAVIF 88
Cdd:PRK07476 20 TPLVASASLSARaGVPVWLKLETLQPTGSFKLRGATNAL-LSLSAQERARG--VVTASTGNHGRALAYAARALGIRATIC 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 89 APEGFSEEKISIIKALGAEVIRT--DQTLGMAGAQKAARDyelqTGAYYLNQFEsyrNPETY--KSTIGKEITDKLKDID 164
Cdd:PRK07476 97 MSRLVPANKVDAIRALGAEVRIVgrSQDDAQAEVERLVRE----EGLTMVPPFD---DPRIIagQGTIGLEILEALPDVA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 165 YFVGGVGSGGTFAGVAEHLAASYRTESVIvepeGSILSGGNA--------HSHDIE-----------GIGSEKWPSF-LP 224
Cdd:PRK07476 170 TVLVPLSGGGLASGVAAAVKAIRPAIRVI----GVSMERGAAmhaslaagRPVQVEevptladslggGIGLDNRYTFaMC 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 225 RALVSDIIKVSDDAAFQNVKLLARQEGLLV-GSSS---GAALQGALEIKkhinKGVIVTI 280
Cdd:PRK07476 246 RALLDDVVLLDEAEIAAGIRHAYREERLVVeGAGAvgiAALLAGKIAAR----DGPIVVV 301
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
61-271 |
6.56e-14 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 71.45 E-value: 6.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 61 VVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKALGAEVIRT----DQTLGMAGAQKAARDYEL-QTGAYy 135
Cdd:PRK08206 118 TFATATDGNHGRGVAWAAQQLGQKAVIYMPKGSSEERVDAIRALGAECIITdgnyDDSVRLAAQEAQENGWVVvQDTAW- 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 136 lnqfESYRNPET-----YkSTIGKEITDKLKDIDY-----FV-GGVGSggtFAG-VAEHLAASY---RTESVIVEPEGS- 199
Cdd:PRK08206 197 ----EGYEEIPTwimqgY-GTMADEAVEQLKEMGVppthvFLqAGVGS---LAGaVLGYFAEVYgeqRPHFVVVEPDQAd 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 200 --ILSGGNAHSHDIEG----------------IGsekWPsFLPRAlVSDIIKVSDDAAFQNVKLLARQEG----LLVGSS 257
Cdd:PRK08206 269 clYQSAVDGKPVAVTGdmdtimaglacgepnpLA---WE-ILRNC-ADAFISCPDEVAALGMRILANPLGgdppIVSGES 343
|
250
....*....|....
gi 1564862654 258 SGAALQGALEIKKH 271
Cdd:PRK08206 344 GAVGLGALAALMTD 357
|
|
| PLN02970 |
PLN02970 |
serine racemase |
23-278 |
7.00e-14 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 70.86 E-value: 7.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 23 VQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIiQKGdvVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIK 102
Cdd:PLN02970 42 RSLFFKCECFQKGGAFKFRGACNAIFSLSDDQA-EKG--VVTHSSGNHAAALALAAKLRGIPAYIVVPKNAPACKVDAVI 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 103 ALGAEVIRTDQTLgMAGAQKAARDYElQTGAYYLNQFEsYRNPETYKSTIGKEITDKLKDIDYFVGGVGSGGTFAGVAeh 182
Cdd:PLN02970 119 RYGGIITWCEPTV-ESREAVAARVQQ-ETGAVLIHPYN-DGRVISGQGTIALEFLEQVPELDVIIVPISGGGLISGIA-- 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 183 LAASYRTES---VIVEPEG------SILSGGNAHSHDIEGI--------GSEKWPsfLPRALVSDIIKVSDDAAFQNVKL 245
Cdd:PLN02970 194 LAAKAIKPSikiIAAEPKGaddaaqSKAAGEIITLPVTNTIadglraslGDLTWP--VVRDLVDDVITVDDKEIIEAMKL 271
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1564862654 246 LARQEGLLVGSSSGAALQGALE--------IKKHINKGVIV 278
Cdd:PLN02970 272 CYERLKVVVEPSGAIGLAAALSdsfrsnpaWKGCKNVGIVL 312
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
23-179 |
2.06e-12 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 66.77 E-value: 2.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 23 VQIYAKLEQYNPGGSVKDRlGKHLIETAIRENIIQKgdvVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIK 102
Cdd:PRK08329 72 IKVYFKLDYLQPTGSFKDR-GTYVTVAKLKEEGINE---VVIDSSGNAALSLALYSLSEGIKVHVFVSYNASKEKISLLS 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 103 ALGAEV--IRTDQtlgMAGAQKAARdYELQTGAYYLNQfesYRNP---ETYKsTIGKEITDKLKDIDYFVGGVGSGGTFA 177
Cdd:PRK08329 148 RLGAELhfVEGDR---MEVHEEAVK-FSKRNNIPYVSH---WLNPyflEGTK-TIAYEIYEQIGVPDYAFVPVGSGTLFL 219
|
..
gi 1564862654 178 GV 179
Cdd:PRK08329 220 GI 221
|
|
| Trp-synth_B |
cd06446 |
Tryptophan synthase-beta: Tryptophan synthase is a bifunctional enzyme that catalyses the ... |
10-280 |
2.20e-12 |
|
Tryptophan synthase-beta: Tryptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to glyceraldehyde 3-phosphate and indole at the active site of the alpha subunit. In the beta reaction, indole undergoes a PLP-dependent reaction with L-serine to form L-tryptophan at the active site of the beta subunit. Members of this CD, Trp-synth_B, are found in all three major phylogenetic divisions.
Pssm-ID: 107207 Cd Length: 365 Bit Score: 66.79 E-value: 2.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK--DVQIYAKLEQYNPGGSvkdrlgkHLIETAIRENIIQKGD----VVVEASAGNTGIGVAIAANHYGV 83
Cdd:cd06446 35 TPLYRAKRLSEYlgGAKIYLKREDLNHTGA-------HKINNALGQALLAKRMgkkrVIAETGAGQHGVATATACALFGL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEGFSEEK---ISIIKALGAEVIRT---DQTLGMAgAQKAARDY--ELQTGAYYLNqfeSYRNPETY------- 148
Cdd:cd06446 108 ECEIYMGAVDVERQplnVFRMELLGAEVVPVpsgSGTLKDA-ISEAIRDWvtNVEDTHYLLG---SVVGPHPYpnmvrdf 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 149 KSTIGKEITDKLKDI-----DYFVGGVGSGGTFAGVAEHLAASYRTESVIVEPEG-SILSGGNA---------------- 206
Cdd:cd06446 184 QSVIGEEAKKQILEKegelpDVVIACVGGGSNAAGLFYPFINDKDVKLIGVEAGGcGLETGGHAaylfggtagvlhglkm 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 207 -------------HSH----DIEGIGSEKwpSFLPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIK 269
Cdd:cd06446 264 ytlqdedgqivppHSIsaglDYPGVGPEH--AYLKDSGRVEYVAVTDEEALEAFKLLARTEGIIPALESSHAIAYAIKLA 341
|
330
....*....|.
gi 1564862654 270 KHINKGVIVTI 280
Cdd:cd06446 342 KKLGKEKVIVV 352
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
4-265 |
1.36e-11 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 64.94 E-value: 1.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 4 FDLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLGKHLIETAIRENIiQKGdvVVEASAGNTGIGVAIAANHYG 82
Cdd:PLN02550 104 YDVAIESPLQLAKKLSERlGVKVLLKREDLQPVFSFKLRGAYNMMAKLPKEQL-DKG--VICSSAGNHAQGVALSAQRLG 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMagAQKAARDYELQTGAYYLNQFEsyrNPE--TYKSTIGKEITDKL 160
Cdd:PLN02550 181 CDAVIAMPVTTPEIKWQSVERLGATVVLVGDSYDE--AQAYAKQRALEEGRTFIPPFD---HPDviAGQGTVGMEIVRQH 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 161 KDIDY--FVgGVGSGGTFAGVAEHLAASYRTESVI-VEPEGS---ILS------------GGNAHSHDIEGIGSEKWPsf 222
Cdd:PLN02550 256 QGPLHaiFV-PVGGGGLIAGIAAYVKRVRPEVKIIgVEPSDAnamALSlhhgervmldqvGGFADGVAVKEVGEETFR-- 332
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1564862654 223 LPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGA 265
Cdd:PLN02550 333 LCRELVDGVVLVSRDAICASIKDMFEEKRSILEPAGALALAGA 375
|
|
| thrC |
TIGR00260 |
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction ... |
8-277 |
3.21e-11 |
|
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction O-PHOSPHO-L-HOMOSERINE + H(2)O = L-THREONINE + ORTHOPHOSPHATE using pyridoxal phosphate as a cofactor. the enzyme is distantly related to the serine/threonine dehydratases which are also pyridoxal-phosphate dependent enzymes. the pyridoxal-phosphate binding site is a Lys (K) residues present at residue 70 of the model. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 272986 [Multi-domain] Cd Length: 327 Bit Score: 63.17 E-value: 3.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLV----LLESFSNKDVqiYAKLEQYNPGGSVKDRLGKHLIeTAIREniiQKGDVVVEASAGNTGIGVAIAANHYGV 83
Cdd:TIGR00260 21 GVTPLFrapaLAANVGIKNL--YVKELGHNPTLSFKDRGMAVAL-TKALE---LGNDTVLCASTGNTGAAAAAYAGKAGL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 84 SAVIFAPEG-FSEEKISIIKALGAEVIRTDQTLGmaGAQKAARDYELQTGAYYLNQFES--YRnPETYKsTIGKEITDKL 160
Cdd:TIGR00260 95 KVVVLYPAGkISLGKLAQALGYNAEVVAIDGNFD--DAQRLVKQLFEDKPALGLNSANSipYR-LEGQK-TYAFEAVEQL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 161 --KDIDYFVGGVGSGGTF----AGVAEH--LAASYRTESVIVEPEGS------ILSGGN----------AHSHDIeGIgs 216
Cdd:TIGR00260 171 gwEAPDKVVVPVPNSGNFgaiwKGFKEKkmLGLDSLPVKRGIQAEGAadivraFLEGGQwepietpetlSTAMDI-GN-- 247
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1564862654 217 ekwPSFLPRAL------VSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGaleIKKHINKGVI 277
Cdd:TIGR00260 248 ---PANWPRALeafrrsNGYAEDLSDEEILEAIKLLAREEGYFVEPHSAVAVAA---LLKLVEKGTA 308
|
|
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
10-284 |
7.74e-11 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 62.06 E-value: 7.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRLG----KHLIETaireniiQKGDVVVEASAGNTGIGVAIAANHYGVS 84
Cdd:PRK08638 28 TPLPRSNYLSERcKGEIFLKLENMQRTGSFKIRGAfnklSSLTDA-------EKRKGVVACSAGNHAQGVALSCALLGID 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 85 AVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQkaARDYELQTGAYYLNqfeSYRNPETY--KSTIGKEITDKLKD 162
Cdd:PRK08638 101 GKVVMPKGAPKSKVAATCGYGAEVVLHGDNFNDTIAK--VEEIVEEEGRTFIP---PYDDPKVIagQGTIGLEILEDLWD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 163 IDYFVGGVGSGGTFAGVAEHL--------------------AASYRTESVIVEPEGSILSGGNahshDIEGIGSEKWPsf 222
Cdd:PRK08638 176 VDTVIVPIGGGGLIAGIAVALksinptihiigvqsenvhgmAASFYAGEITTHRTTGTLADGC----DVSRPGNLTYE-- 249
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1564862654 223 LPRALVSDIIKVSDDAAFQNVKLLArQEGLLVGSSSGAALQGALE---IKKHINKGVIVTIFPDG 284
Cdd:PRK08638 250 IVRELVDDIVLVSEDEIRNAMKDLI-QRNKVVTEGAGALATAALLsgkLDQYIQNKKVVAIISGG 313
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
8-135 |
1.62e-10 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 60.90 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFsnkdvqiYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQkgdvVVEASAGNTGIGVAIAANHYGVSAVI 87
Cdd:PRK06450 57 GRTPLIKKGNI-------WFKLDFLNPTGSYKDRGSVTLISYLAEKGIKQ----ISEDSSGNAGASIAAYGAAAGIEVKI 125
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1564862654 88 FAPEGFSEEKISIIKALGAEVIRTDQTlgMAGAQKAARdyelQTGAYY 135
Cdd:PRK06450 126 FVPETASGGKLKQIESYGAEVVRVRGS--REDVAKAAE----NSGYYY 167
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
4-199 |
5.19e-10 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 59.81 E-value: 5.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 4 FDLIGNTPLVLLESFSNK-DVQIYAKLEQYNPGGSVKDRlGKHLIETAIRENIIQKGdvVVEASAGNTGIGVAIAANHYG 82
Cdd:PRK12483 32 YDVARETPLQRAPNLSARlGNQVLLKREDLQPVFSFKIR-GAYNKMARLPAEQLARG--VITASAGNHAQGVALAAARLG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 83 VSAVIFAPEGFSEEKISIIKALGAEVIRTDQTL--GMAGAQKAARdyelQTGAYYLNQFEsyrNPETY--KSTIGKEITD 158
Cdd:PRK12483 109 VKAVIVMPRTTPQLKVDGVRAHGGEVVLHGESFpdALAHALKLAE----EEGLTFVPPFD---DPDVIagQGTVAMEILR 181
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1564862654 159 KLKD-IDYFVGGVGSGGTFAGVAEHLAASYRTESVI-VEPEGS 199
Cdd:PRK12483 182 QHPGpLDAIFVPVGGGGLIAGIAAYVKYVRPEIKVIgVEPDDS 224
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
10-262 |
6.98e-10 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 59.25 E-value: 6.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSnkdvqIYAKLEQYNPGGSVKDRLGKHLIETAIreniiQKGD--VVVEASAGNTGIGVAIAANHYGVSAVI 87
Cdd:PRK08813 40 TPLHYAERFG-----VWLKLENLQRTGSYKVRGALNALLAGL-----ERGDerPVICASAGNHAQGVAWSAYRLGVQAIT 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 88 FAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAqkAARDYELQTGAYYLNQFEsyrNPETY--KSTIGKEITDKLKDIdy 165
Cdd:PRK08813 110 VMPHGAPQTKIAGVAHWGATVRQHGNSYDEAYA--FARELADQNGYRFLSAFD---DPDVIagQGTVGIELAAHAPDV-- 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 166 FVGGVGSGGTFAGVAEHLaasyRTESVIVepEGSILSGGNAHSHDIEGIGSE-------------KWPSFLPRALVS--- 229
Cdd:PRK08813 183 VIVPIGGGGLASGVALAL----KSQGVRV--VGAQVEGVDSMARAIRGDLREiapvatladgvkvKIPGFLTRRLCSsll 256
|
250 260 270
....*....|....*....|....*....|....
gi 1564862654 230 -DIIKVSDDAAFQNVKLLARQEGLLVGSSSGAAL 262
Cdd:PRK08813 257 dDVVIVREAELRETLVRLALEEHVIAEGAGALAL 290
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
24-109 |
1.66e-09 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 57.70 E-value: 1.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 24 QIYAKLEQYNPGGSVKDRLGKHLIETAIRENIIQKGdvVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKA 103
Cdd:PRK06110 37 EVWVKHENHTPTGAFKVRGGLVYFDRLARRGPRVRG--VISATRGNHGQSVAFAARRHGLAATIVVPHGNSVEKNAAMRA 114
|
....*.
gi 1564862654 104 LGAEVI 109
Cdd:PRK06110 115 LGAELI 120
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
10-141 |
2.57e-09 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 57.47 E-value: 2.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFsNKDV--QIYAKLEQYNPGGSVKDRLG-KHLIETAIRENIIQKgdvVVEASAGNTGIGVAIAANHYGVSAV 86
Cdd:PRK06608 24 TPIVHSESL-NEMLghEIFFKVESLQKTGAFKVRGVlNHLLELKEQGKLPDK---IVAYSTGNHGQAVAYASKLFGIKTR 99
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1564862654 87 IFAPEGFSEEKISIIKALGAEVIRTDQTlgmAGAQKAARDYELQtGAYYLNQFES 141
Cdd:PRK06608 100 IYLPLNTSKVKQQAALYYGGEVILTNTR---QEAEEKAKEDEEQ-GFYYIHPSDS 150
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
57-238 |
4.29e-09 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 57.07 E-value: 4.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 57 QKGdvVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKALGAEVIrtdqtlgMAG-----AQKAARDYELQT 131
Cdd:PRK09224 68 ARG--VITASAGNHAQGVALSAARLGIKAVIVMPVTTPDIKVDAVRAFGGEVV-------LHGdsfdeAYAHAIELAEEE 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 132 GAYYLNQFEsyrNPETY--KSTIGKEITDKLKD-IDY-FVgGVGSGGTFAGVAEHLAASYRTESVI-VEPEGS------- 199
Cdd:PRK09224 139 GLTFIHPFD---DPDVIagQGTIAMEILQQHPHpLDAvFV-PVGGGGLIAGVAAYIKQLRPEIKVIgVEPEDSaclkaal 214
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1564862654 200 ------------ILSGGNAhshdIEGIGSEKWPsfLPRALVSDIIKVSDDA 238
Cdd:PRK09224 215 eagervdlpqvgLFADGVA----VKRIGEETFR--LCQEYVDDVITVDTDE 259
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
8-285 |
9.39e-09 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 55.97 E-value: 9.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFSNKDVQIYAKLEQYNPGGSVKDRLgkhlIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGVSAVI 87
Cdd:PRK05638 65 GGTPLIRARISEKLGENVYIKDETRNPTGSFRDRL----ATVAVSYGLPYAANGFIVASDGNAAASVAAYSARAGKEAFV 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 88 FAPEGFSEEKISIIKALGAEVIRTDQTLGMAgAQKAARDYELQtGAYYLNQFESYRNPETYKsTIGKEITDKLKDIDYFV 167
Cdd:PRK05638 141 VVPRKVDKGKLIQMIAFGAKIIRYGESVDEA-IEYAEELARLN-GLYNVTPEYNIIGLEGQK-TIAFELWEEINPTHVIV 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 168 gGVGSGGTF------------AGVAEHLAASYRTESVIVEPEGSILSGGNAHSHDIEGIG-SEKWPsfLPRALVSDIIKV 234
Cdd:PRK05638 218 -PTGSGSYLysiykgfkelleIGVIEEIPKLIAVQTERCNPIASEILGNKTKCNETKALGlYVKNP--VMKEYVSEAIKE 294
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 235 SDDAAFQN-------VKLLARQEGLLVGSSSGAALQGALEIKK--HINKGVIVTIFPDGS 285
Cdd:PRK05638 295 SGGTAVVVneeeimaGEKLLAKEGIFAELSSAVVMPALLKLGEegYIEKGDKVVLVVTGS 354
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
57-279 |
1.04e-08 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 55.41 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 57 QKGDVVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKALGAEVIRTDQTlgMAGAQKAARDYELQTGayyL 136
Cdd:PRK07048 70 QRRAGVVTFSSGNHAQAIALSARLLGIPATIVMPQDAPAAKVAATRGYGGEVVTYDRY--TEDREEIGRRLAEERG---L 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 137 NQFESYRNPETY--KSTIGKEITDKLKDIDYFVGGVGSGGTFAGVAehLAA---SYRTESVIVEPEG------SILSGGN 205
Cdd:PRK07048 145 TLIPPYDHPHVIagQGTAAKELFEEVGPLDALFVCLGGGGLLSGCA--LAAralSPGCKVYGVEPEAgndgqqSFRSGEI 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 206 AHSHDIEGI---------GSEKWPsfLPRALVSDIIKVSDDAAFQNVKLLARQEGLLV---GS-SSGAALQGALEIK-KH 271
Cdd:PRK07048 223 VHIDTPRTIadgaqtqhlGNYTFP--IIRRLVDDIVTVSDAELVDAMRFFAERMKIVVeptGClGAAAALRGKVPLKgKR 300
|
....*...
gi 1564862654 272 InkGVIVT 279
Cdd:PRK07048 301 V--GVIIS 306
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
24-262 |
4.35e-08 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 53.74 E-value: 4.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 24 QIYAKLEQYNPGGSVKDR--LGKHLietAIRENIIQKGdvVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISII 101
Cdd:PRK07334 39 EVWLKFENLQFTASFKERgaLNKLL---LLTEEERARG--VIAMSAGNHAQGVAYHAQRLGIPATIVMPRFTPTVKVERT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 102 KALGAEVIRTDQTLGMAGAQkaARDYELQTGayyLNQFESYRNPETY--KSTIGKEITDKLKDIDYFVGGVGSGGTFAGV 179
Cdd:PRK07334 114 RGFGAEVVLHGETLDEARAH--ARELAEEEG---LTFVHPYDDPAVIagQGTVALEMLEDAPDLDTLVVPIGGGGLISGM 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 180 AEHLAASYRTESVI-VEPE----------GSILSGGnaHSHDIEGIgSEKWPSFLP----RALVSDIIKVSDDAAFQNVK 244
Cdd:PRK07334 189 ATAAKALKPDIEIIgVQTElypsmyaaikGVALPCG--GSTIAEGI-AVKQPGQLTleivRRLVDDILLVSEADIEQAVS 265
|
250 260
....*....|....*....|.
gi 1564862654 245 LLARQEGLLV---GSSSGAAL 262
Cdd:PRK07334 266 LLLEIEKTVVegaGAAGLAAL 286
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
8-267 |
2.21e-06 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 48.46 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 8 GNTPLVLLESFSnKDV---QIYAKLEQYNPGGSVKDRlGKHLIETAIRENIIQKgdvVVEASAGNTGIGVAIAANHYGVS 84
Cdd:PRK08197 78 GMTPLLPLPRLG-KALgigRLWVKDEGLNPTGSFKAR-GLAVGVSRAKELGVKH---LAMPTNGNAGAAWAAYAARAGIR 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 85 AVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQ--KAARDYelqtGAYYLNQF-ESYRnPETyKSTIGKEITD--- 158
Cdd:PRK08197 153 ATIFMPADAPEITRLECALAGAELYLVDGLISDAGKIvaEAVAEY----GWFDVSTLkEPYR-IEG-KKTMGLELAEqlg 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 159 -KLKD-IDYFV-GGVGSGGTFAGVAEhLAA-----SYRTESVIVEPEG--SILSGGNAHSHDiegigSEKWP-----SF- 222
Cdd:PRK08197 227 wRLPDvILYPTgGGVGLIGIWKAFDE-LEAlgwigGKRPRLVAVQAEGcaPIVKAWEEGKEE-----SEFWEdahtvAFg 300
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1564862654 223 --LPRA----LVSDIIK--------VSDDAAFQNVKLLARQEGLLV---GSSSGAALQGALE 267
Cdd:PRK08197 301 irVPKAlgdfLVLDAVRetggcaiaVSDDAILAAQRELAREEGLFAcpeGAATFAAARQLRE 362
|
|
| PRK13803 |
PRK13803 |
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional |
10-301 |
3.50e-06 |
|
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional
Pssm-ID: 237513 [Multi-domain] Cd Length: 610 Bit Score: 48.27 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 10 TPLVLLESFSNK-DVQIYAKLEQYNPGGSVK--DRLGKHLIetAIReniIQKGDVVVEASAGNTGIGVAIAANHYGVSAV 86
Cdd:PRK13803 272 TPLTEAKRLSDIyGARIYLKREDLNHTGSHKinNALGQALL--AKR---MGKTRIIAETGAGQHGVATATACALFGLKCT 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 87 IFAPE---GFSEEKISIIKALGAEVIRT---DQTLGMAgAQKAARDYELQT-GAYYLnqFESYRNPETY-------KSTI 152
Cdd:PRK13803 347 IFMGEediKRQALNVERMKLLGANVIPVlsgSKTLKDA-VNEAIRDWVASVpDTHYL--IGSAVGPHPYpemvayfQSVI 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 153 GKEITDKLKDI-----DYFVGGVGSGGTFAGVAEHLAASYRTESVIVEPEG------------------------SIL-- 201
Cdd:PRK13803 424 GEEAKEQLKEQtgklpDAIIACVGGGSNAIGIFYHFLDDPSVKLIGVEAGGkgvntgehaatikkgrkgvlhgsmTYLmq 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1564862654 202 --SGGNAHSHDIE------GIGSEKwpSFLPRALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAAL----QGALEIK 269
Cdd:PRK13803 504 deNGQILEPHSISagldypGIGPMH--ANLFETGRAIYTSVTDEEALDAFKLLAKLEGIIPALESSHALaylkEGRKKFK 581
|
330 340 350
....*....|....*....|....*....|..
gi 1564862654 270 KhiNKGVIVTIFPDGsdrymSKQILNYKETIK 301
Cdd:PRK13803 582 K--KDIVIVNLSGRG-----DKDIPTLKEYFE 606
|
|
| |
