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Conserved domains on  [gi|1544501189|gb|RUF93169|]
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TetR/AcrR family transcriptional regulator [Pseudomonas aeruginosa]

Protein Classification

TetR/AcrR family transcriptional regulator( domain architecture ID 15816313)

TetR/AcrR family transcriptional regulator controls genes involved in a variety of processes including antibiotic production, osmotic stress response, efflux pump expression, and multidrug resistance

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TetR_C_30 pfam17939
Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the ...
93-206 6.20e-28

Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in the Pseudomonas aeruginosa PsrA which regulates the fadBA5 beta-oxidation operon. Functional analysis of PsrA indicated its importance in regulating b-oxidative enzymes. It has also been suggested that PsrA, a member of the TetR family of repressors, could affect global gene expression including activation of rpoS.


:

Pssm-ID: 465577  Cd Length: 113  Bit Score: 102.31  E-value: 6.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189  93 LVSQAMAVKPRSGNDLSIFMRLLGLAFSQSQGHLRKYLEEVYGKVFRRYMLLVNEAAPKLPPIELFWRVHFMLGAAAFSM 172
Cdd:pfam17939   1 FVRPLLELSQTGGEGGRAFARLLARLYSEPDEELRELIAEEYDPVARRFIAALRRALPDLPREELFWRLHFMLGALLFTL 80
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1544501189 173 SGIKALRAMAEtDFGVNTSTEQVMHLMVPFFAAG 206
Cdd:pfam17939  81 ADTGRLDILSG-GLCSSADLEALIERLVPFLAAG 113
septum_RefZ super family cl41571
forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in ...
8-95 3.29e-15

forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in the family of TetR/AcrR family transcriptional regulators, participates in septum placement and in chromosome capture during the asymmetrical cell division in endospore formation. The five nearly palindromic DNA motifs (RBMs) to which RefZ binds affect chromosomal localization, not transcription, so RefZ is not considered a transcription factor.


The actual alignment was detected with superfamily member NF037937:

Pssm-ID: 468281 [Multi-domain]  Cd Length: 195  Bit Score: 71.40  E-value: 3.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRqaKPEAQHATLE 87
Cdd:NF037937    2 EKILDAAISLFNTKGFDGTSVRDIAKKAKVNVALISYYFKGKQGLLEYLVTSFFEGYLEILEEGFEEL--KNLSAKECLK 79

                  ....*...
gi 1544501189  88 DLLHLLVS 95
Cdd:NF037937   80 QLVRNILH 87
 
Name Accession Description Interval E-value
TetR_C_30 pfam17939
Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the ...
93-206 6.20e-28

Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in the Pseudomonas aeruginosa PsrA which regulates the fadBA5 beta-oxidation operon. Functional analysis of PsrA indicated its importance in regulating b-oxidative enzymes. It has also been suggested that PsrA, a member of the TetR family of repressors, could affect global gene expression including activation of rpoS.


Pssm-ID: 465577  Cd Length: 113  Bit Score: 102.31  E-value: 6.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189  93 LVSQAMAVKPRSGNDLSIFMRLLGLAFSQSQGHLRKYLEEVYGKVFRRYMLLVNEAAPKLPPIELFWRVHFMLGAAAFSM 172
Cdd:pfam17939   1 FVRPLLELSQTGGEGGRAFARLLARLYSEPDEELRELIAEEYDPVARRFIAALRRALPDLPREELFWRLHFMLGALLFTL 80
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1544501189 173 SGIKALRAMAEtDFGVNTSTEQVMHLMVPFFAAG 206
Cdd:pfam17939  81 ADTGRLDILSG-GLCSSADLEALIERLVPFLAAG 113
septum_RefZ NF037937
forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in ...
8-95 3.29e-15

forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in the family of TetR/AcrR family transcriptional regulators, participates in septum placement and in chromosome capture during the asymmetrical cell division in endospore formation. The five nearly palindromic DNA motifs (RBMs) to which RefZ binds affect chromosomal localization, not transcription, so RefZ is not considered a transcription factor.


Pssm-ID: 468281 [Multi-domain]  Cd Length: 195  Bit Score: 71.40  E-value: 3.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRqaKPEAQHATLE 87
Cdd:NF037937    2 EKILDAAISLFNTKGFDGTSVRDIAKKAKVNVALISYYFKGKQGLLEYLVTSFFEGYLEILEEGFEEL--KNLSAKECLK 79

                  ....*...
gi 1544501189  88 DLLHLLVS 95
Cdd:NF037937   80 QLVRNILH 87
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
5-167 7.67e-15

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 69.54  E-value: 7.67e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   5 ETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKpEAQHA 84
Cdd:COG1309     6 ATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALEEALAAEDPR-ERLRA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189  85 TLEDLLHLLVSQAmavkprsgndlsiFMRLLGLAFSQSQGHLRKYLEEVYgKVFRRYMLLVNEAAPKLPPIELFWRVHFM 164
Cdd:COG1309    85 LLRAYLEFLAENP-------------ALARLLLAEAAELPELRAALRALL-RRLRALLAELLRAGGLLADVDPDALARAL 150

                  ...
gi 1544501189 165 LGA 167
Cdd:COG1309   151 LAL 153
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
10-56 4.24e-12

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 58.96  E-value: 4.24e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1544501189  10 ILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAV 56
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
6-110 9.06e-11

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 59.15  E-value: 9.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   6 TVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKPEaqhaT 85
Cdd:NF041196    7 TRRAILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEALARAVLEEQVARLREAVEPQRAGGGSKLQ----E 82
                          90       100
                  ....*....|....*....|....*.
gi 1544501189  86 LEDLLHLLVSQAMA-VKPRSGNDLSI 110
Cdd:NF041196   83 LVDLTHVLARRLRTdPVVRAGVRLSI 108
PRK11552 PRK11552
putative DNA-binding transcriptional regulator; Provisional
8-91 4.08e-08

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 236928 [Multi-domain]  Cd Length: 225  Bit Score: 51.98  E-value: 4.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSlRLITSKAGVNLAAVNYHFGSKKALIQAV---FSRFLGPFCASLEKELDRRQAKPEAQHA 84
Cdd:PRK11552   16 QQLIAAALAQFGEYGLHATT-RDIAAQAGQNIAAITYYFGSKEDLYLAVaqwIADFIGEQFRPHAEEAERLFAQPAPDRA 94

                  ....*..
gi 1544501189  85 TLEDLLH 91
Cdd:PRK11552   95 AIRELIL 101
 
Name Accession Description Interval E-value
TetR_C_30 pfam17939
Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the ...
93-206 6.20e-28

Tetracyclin repressor-like, C-terminal domain; TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in the Pseudomonas aeruginosa PsrA which regulates the fadBA5 beta-oxidation operon. Functional analysis of PsrA indicated its importance in regulating b-oxidative enzymes. It has also been suggested that PsrA, a member of the TetR family of repressors, could affect global gene expression including activation of rpoS.


Pssm-ID: 465577  Cd Length: 113  Bit Score: 102.31  E-value: 6.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189  93 LVSQAMAVKPRSGNDLSIFMRLLGLAFSQSQGHLRKYLEEVYGKVFRRYMLLVNEAAPKLPPIELFWRVHFMLGAAAFSM 172
Cdd:pfam17939   1 FVRPLLELSQTGGEGGRAFARLLARLYSEPDEELRELIAEEYDPVARRFIAALRRALPDLPREELFWRLHFMLGALLFTL 80
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1544501189 173 SGIKALRAMAEtDFGVNTSTEQVMHLMVPFFAAG 206
Cdd:pfam17939  81 ADTGRLDILSG-GLCSSADLEALIERLVPFLAAG 113
septum_RefZ NF037937
forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in ...
8-95 3.29e-15

forespore capture DNA-binding protein RefZ; RefZ (regulator of FtsZ), a DNA-binding protein in the family of TetR/AcrR family transcriptional regulators, participates in septum placement and in chromosome capture during the asymmetrical cell division in endospore formation. The five nearly palindromic DNA motifs (RBMs) to which RefZ binds affect chromosomal localization, not transcription, so RefZ is not considered a transcription factor.


Pssm-ID: 468281 [Multi-domain]  Cd Length: 195  Bit Score: 71.40  E-value: 3.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRqaKPEAQHATLE 87
Cdd:NF037937    2 EKILDAAISLFNTKGFDGTSVRDIAKKAKVNVALISYYFKGKQGLLEYLVTSFFEGYLEILEEGFEEL--KNLSAKECLK 79

                  ....*...
gi 1544501189  88 DLLHLLVS 95
Cdd:NF037937   80 QLVRNILH 87
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
5-167 7.67e-15

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 69.54  E-value: 7.67e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   5 ETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKpEAQHA 84
Cdd:COG1309     6 ATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALEEALAAEDPR-ERLRA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189  85 TLEDLLHLLVSQAmavkprsgndlsiFMRLLGLAFSQSQGHLRKYLEEVYgKVFRRYMLLVNEAAPKLPPIELFWRVHFM 164
Cdd:COG1309    85 LLRAYLEFLAENP-------------ALARLLLAEAAELPELRAALRALL-RRLRALLAELLRAGGLLADVDPDALARAL 150

                  ...
gi 1544501189 165 LGA 167
Cdd:COG1309   151 LAL 153
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
10-56 4.24e-12

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 58.96  E-value: 4.24e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1544501189  10 ILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAV 56
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
6-110 9.06e-11

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 59.15  E-value: 9.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   6 TVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKPEaqhaT 85
Cdd:NF041196    7 TRRAILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEALARAVLEEQVARLREAVEPQRAGGGSKLQ----E 82
                          90       100
                  ....*....|....*....|....*.
gi 1544501189  86 LEDLLHLLVSQAMA-VKPRSGNDLSI 110
Cdd:NF041196   83 LVDLTHVLARRLRTdPVVRAGVRLSI 108
YbjK COG3226
DNA-binding transcriptional regulator YbjK [Transcription];
8-93 1.77e-09

DNA-binding transcriptional regulator YbjK [Transcription];


Pssm-ID: 442459 [Multi-domain]  Cd Length: 191  Bit Score: 55.33  E-value: 1.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLEKELDRRQAKPEAQHATLE 87
Cdd:COG3226    11 ERILEAALRVIARDGVRGVTHRAVAAEAGVPLGSTTYYFRTRDELLAAAFERLAEREAARLRALLAAADDLEDAAEALAD 90

                  ....*.
gi 1544501189  88 DLLHLL 93
Cdd:COG3226    91 LLAELL 96
PRK11552 PRK11552
putative DNA-binding transcriptional regulator; Provisional
8-91 4.08e-08

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 236928 [Multi-domain]  Cd Length: 225  Bit Score: 51.98  E-value: 4.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSlRLITSKAGVNLAAVNYHFGSKKALIQAV---FSRFLGPFCASLEKELDRRQAKPEAQHA 84
Cdd:PRK11552   16 QQLIAAALAQFGEYGLHATT-RDIAAQAGQNIAAITYYFGSKEDLYLAVaqwIADFIGEQFRPHAEEAERLFAQPAPDRA 94

                  ....*..
gi 1544501189  85 TLEDLLH 91
Cdd:PRK11552   95 AIRELIL 101
PRK10668 PRK10668
DNA-binding transcriptional repressor AcrR; Provisional
5-52 8.92e-06

DNA-binding transcriptional repressor AcrR; Provisional


Pssm-ID: 182632 [Multi-domain]  Cd Length: 215  Bit Score: 45.00  E-value: 8.92e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1544501189   5 ETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKAL 52
Cdd:PRK10668   11 ETRQHILDAALRLFSQQGVSATSLADIAKAAGVTRGAIYWHFKNKSDL 58
PRK09975 PRK09975
DNA-binding transcriptional regulator EnvR; Provisional
6-103 6.88e-05

DNA-binding transcriptional regulator EnvR; Provisional


Pssm-ID: 182177 [Multi-domain]  Cd Length: 213  Bit Score: 42.42  E-value: 6.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   6 TVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLgPFCaslekELDRRQAKPEAQHAT 85
Cdd:PRK09975   12 TRQELIETAIAQFALRGVSNTTLNDIADAANVTRGAIYWHFENKTQLFNEMWLQQP-PLR-----ELIQEHLTAGLEHDP 85
                          90       100
                  ....*....|....*....|
gi 1544501189  86 LEDLLHLLVS--QAMAVKPR 103
Cdd:PRK09975   86 LQQLREKFIAglQYIAKIPR 105
PRK14996 PRK14996
TetR family transcriptional regulator; Provisional
8-94 8.33e-04

TetR family transcriptional regulator; Provisional


Pssm-ID: 184958 [Multi-domain]  Cd Length: 192  Bit Score: 39.31  E-value: 8.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1544501189   8 ERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRflgpfcasLEKELDrrQAKPEAQHATLE 87
Cdd:PRK14996   11 EVILQAAMRVALAEGFAAMTVRRIASEAQVAAGQVHHHFSSAGELKALAFIH--------LIRQLL--DAEQVPQTASWR 80

                  ....*..
gi 1544501189  88 DLLHLLV 94
Cdd:PRK14996   81 ERLHAML 87
PRK15008 PRK15008
HTH-type transcriptional regulator RutR; Provisional
2-69 1.66e-03

HTH-type transcriptional regulator RutR; Provisional


Pssm-ID: 184970 [Multi-domain]  Cd Length: 212  Bit Score: 38.37  E-value: 1.66e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1544501189   2 AQSETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGPFCASLE 69
Cdd:PRK15008   15 AVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLK 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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