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Conserved domains on  [gi|1518349244|gb|RPD18781|]
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RNA polymerase factor sigma-32 [Neisseria meningitidis]

Protein Classification

RNA polymerase sigma factor RpoH( domain architecture ID 11482333)

RNA polymerase sigma factor RpoH is involved in regulating the expression of heat shock genes; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

Gene Ontology:  GO:0016987|GO:0003677|GO:0006352
PubMed:  3315851|3052291

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 2.44e-170

RNA polymerase factor sigma-32; Reviewed


:

Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 472.35  E-value: 2.44e-170
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244   1 MNNAFALPAIqSGNGSLEQYIHTVNSIPMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLI 79
Cdd:PRK06596    1 MTKALQLLAL-SPEGNLDAYIQAVNKIPMLTAEEEYMLAKRlREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  80 QEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNALSPKEAQDIAD 159
Cdd:PRK06596   80 QEGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 160 DLGVKLSEVLEMEQRMTGHDIAIMA-DNSDDEDSFAPIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIV 238
Cdd:PRK06596  160 ELGVSEEEVREMESRLSGQDASLDApIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1518349244 239 ESRWLQDDgGLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFLTEEA 284
Cdd:PRK06596  240 EARWLDDD-KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 2.44e-170

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 472.35  E-value: 2.44e-170
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244   1 MNNAFALPAIqSGNGSLEQYIHTVNSIPMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLI 79
Cdd:PRK06596    1 MTKALQLLAL-SPEGNLDAYIQAVNKIPMLTAEEEYMLAKRlREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  80 QEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNALSPKEAQDIAD 159
Cdd:PRK06596   80 QEGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 160 DLGVKLSEVLEMEQRMTGHDIAIMA-DNSDDEDSFAPIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIV 238
Cdd:PRK06596  160 ELGVSEEEVREMESRLSGQDASLDApIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1518349244 239 ESRWLQDDgGLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFLTEEA 284
Cdd:PRK06596  240 EARWLDDD-KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
15-281 5.69e-160

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 445.57  E-value: 5.69e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  15 GSLEQYIHTVNSIPMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRY 93
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRlREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  94 EPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNA-LSPKEAQDIADDLGVKLSEVLEME 172
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLQGwLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 173 QRMTGHDIAIMADNSDDEDSF-APIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIVESRWLQDDgGLTL 251
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGgAPIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD-KLTL 239
                         250       260       270
                  ....*....|....*....|....*....|
gi 1518349244 252 HQLAAEYGVSAERIRQIEAKAMQKLRGFLT 281
Cdd:TIGR02392 240 QELAAEYGVSAERIRQIEKNAMKKLKAALA 269
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
19-284 2.66e-104

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 304.67  E-value: 2.66e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  19 QYIHTVNSIPMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRG 98
Cdd:COG0568     1 AYLREIGRVPLLTAEEEVELARRIQAGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPERG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  99 ARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQ--RKlffnLRSMRKNLNA--LSPKEAQDIADDLGVKLSEVLEMEqR 174
Cdd:COG0568    81 FRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlNK----LRRAKRQLLQelGREPTPEEIAEELGVPEEKVREML-R 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 175 MTGHDIAIMADNSDDEDSfAPIDWLADHDSE-PSRQLSKQahyaLQTEGLQNALAQLDDRSRRIVESRWLQDDG-GLTLH 252
Cdd:COG0568   156 LAREPVSLDAPVGDDEDS-ELGDLLEDEEAPsPEEALEEE----LLREELREALDTLTEREREILRLRFGLDDGePHTLE 230
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1518349244 253 QLAAEYGVSAERIRQIEAKAMQKLRGFLTEEA 284
Cdd:COG0568   231 EIGKEFGVSRERVRQIEAKALRKLRHPLRSRK 262
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
53-122 5.11e-16

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 71.08  E-value: 5.11e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  53 LILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWR 122
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
223-277 9.20e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 53.26  E-value: 9.20e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1518349244 223 LQNALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:cd06171     4 LEEALDKLPEREREVILLRFGE---GLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 2.44e-170

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 472.35  E-value: 2.44e-170
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244   1 MNNAFALPAIqSGNGSLEQYIHTVNSIPMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLI 79
Cdd:PRK06596    1 MTKALQLLAL-SPEGNLDAYIQAVNKIPMLTAEEEYMLAKRlREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  80 QEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNALSPKEAQDIAD 159
Cdd:PRK06596   80 QEGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 160 DLGVKLSEVLEMEQRMTGHDIAIMA-DNSDDEDSFAPIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIV 238
Cdd:PRK06596  160 ELGVSEEEVREMESRLSGQDASLDApIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1518349244 239 ESRWLQDDgGLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFLTEEA 284
Cdd:PRK06596  240 EARWLDDD-KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
15-281 5.69e-160

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 445.57  E-value: 5.69e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  15 GSLEQYIHTVNSIPMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRY 93
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRlREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  94 EPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNA-LSPKEAQDIADDLGVKLSEVLEME 172
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLQGwLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 173 QRMTGHDIAIMADNSDDEDSF-APIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIVESRWLQDDgGLTL 251
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGgAPIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD-KLTL 239
                         250       260       270
                  ....*....|....*....|....*....|
gi 1518349244 252 HQLAAEYGVSAERIRQIEAKAMQKLRGFLT 281
Cdd:TIGR02392 240 QELAAEYGVSAERIRQIEKNAMKKLKAALA 269
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
19-284 2.66e-104

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 304.67  E-value: 2.66e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  19 QYIHTVNSIPMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRG 98
Cdd:COG0568     1 AYLREIGRVPLLTAEEEVELARRIQAGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPERG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  99 ARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQ--RKlffnLRSMRKNLNA--LSPKEAQDIADDLGVKLSEVLEMEqR 174
Cdd:COG0568    81 FRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlNK----LRRAKRQLLQelGREPTPEEIAEELGVPEEKVREML-R 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 175 MTGHDIAIMADNSDDEDSfAPIDWLADHDSE-PSRQLSKQahyaLQTEGLQNALAQLDDRSRRIVESRWLQDDG-GLTLH 252
Cdd:COG0568   156 LAREPVSLDAPVGDDEDS-ELGDLLEDEEAPsPEEALEEE----LLREELREALDTLTEREREILRLRFGLDDGePHTLE 230
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1518349244 253 QLAAEYGVSAERIRQIEAKAMQKLRGFLTEEA 284
Cdd:COG0568   231 EIGKEFGVSRERVRQIEAKALRKLRHPLRSRK 262
rpoH2 PRK07500
RNA polymerase factor sigma-32; Reviewed
28-287 3.90e-67

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 236033 [Multi-domain]  Cd Length: 289  Bit Score: 210.66  E-value: 3.90e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  28 PMLSQEEETRLAER-RIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAV 106
Cdd:PRK07500   19 PYLEREEEHALAYRwKDHRDEDALHRIISAHMRLVISMAGKFRRFGLPMNDLIQEGYVGLLEAAARFEPDREVRFSTYAT 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 107 HWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNL----NALSPKEA-QDIADDLGVKLSEVLEMEQRMTGHDIA 181
Cdd:PRK07500   99 WWIRASIQDYILRNWSIVRGGTSSAQKALFFNLRRLRARLaqadEELTKQEIhREIATALGVSLSDVEMMDARLSGPDAS 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 182 IMAD-NSDDEDSFAPIDWLADHDSEPSRQLSKQAHYALQTEGLQNALAQLDDRSRRIVESRWLQDDGGlTLHQLAAEYGV 260
Cdd:PRK07500  179 LNAPqSEEDEGRSERMDFLVDDSPLPDEQVESSIDGERRRRWLTQALQTLNERELRIIRERRLREDGA-TLEALGEELGI 257
                         250       260
                  ....*....|....*....|....*..
gi 1518349244 261 SAERIRQIEAKAMQKLRGFLTEEAEAV 287
Cdd:PRK07500  258 SKERVRQIEARALEKLRRALLSQSPEV 284
PRK09210 PRK09210
RNA polymerase sigma factor RpoD; Validated
20-277 5.22e-35

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236413 [Multi-domain]  Cd Length: 367  Bit Score: 129.33  E-value: 5.22e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  20 YIHTVNSIPMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGA 99
Cdd:PRK09210  101 YLKEIGRVPLLTAEEEIELAKRIEEGDEEAKQRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLMKAVEKFDYRKGF 180
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 100 RLFSFAVHWIKAEIHEFILRNWRLVR--VATTKPQRKLffnLRSMRKNLNAL----SPKEaqdIADDLGV---KLSEVLE 170
Cdd:PRK09210  181 KFSTYATWWIRQAITRAIADQARTIRipVHMVETINKL---IRVQRQLLQELgrepTPEE---IAEEMDMppeKVREILK 254
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 171 MEQRMTGHDIAImadnSDDEDSFAPiDWLADHDSEPSrqlSKQAHYALQTEGLQNALAQLDDRSRRIVESRWLQDDGGL- 249
Cdd:PRK09210  255 IAQEPVSLETPI----GEEDDSHLG-DFIEDQDATSP---ADHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTr 326
                         250       260
                  ....*....|....*....|....*...
gi 1518349244 250 TLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK09210  327 TLEEVGKVFGVTRERIRQIEAKALRKLR 354
PRK05657 PRK05657
RNA polymerase sigma factor RpoS; Validated
22-280 1.43e-32

RNA polymerase sigma factor RpoS; Validated


Pssm-ID: 235548 [Multi-domain]  Cd Length: 325  Bit Score: 121.99  E-value: 1.43e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  22 HTVNSI---PMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRG 98
Cdd:PRK05657   57 LYLNEIgysPLLTAEEEVYFARRALRGDFAARQRMIESNLRLVVKIAKRYLNRGLALLDLIEEGNLGLIRAVEKFDPERG 136
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  99 ARLFSFAVHWIKAEIHEFILRNWRLVRVattkPQ---RKLFFNLRSMRkNLNALSPKEA--QDIADDLGVKLSEV---LE 170
Cdd:PRK05657  137 FRFSTYATWWIRQTIERAIMNQTRTIRL----PVhvvKELNVYLRAAR-ELEHKLDHEPsaEEIAELLDKPVDDVsrmLA 211
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 171 MEQRMTGHDIAImadnsdDEDSFAPI-DWLAD-HDSEPSRQLskqAHYALQTEgLQNALAQLDDRSRRIVESRW-LQDDG 247
Cdd:PRK05657  212 LNERITSLDTPL------GGDPEKSLlDILADeQENGPEDTT---QDDDMKQS-IVKWLFELNDKQREVLARRFgLLGYE 281
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1518349244 248 GLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFL 280
Cdd:PRK05657  282 AATLEDVAREIGLTRERVRQIQVEALRRLREIL 314
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
34-282 1.42e-30

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 114.54  E-value: 1.42e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  34 EETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDG-YGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAE 112
Cdd:COG1191     1 DLEELLRRYQEGDEEAREELIEEYLPLVKKIASRLAGrLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 113 I-HEFILRNWRLVRVattkpqRKLFFNLRSMRKNL---NALSPKEAQdIADDLGVKLSEVLEMEQRMTGHDIAIMADNSD 188
Cdd:COG1191    81 IlDYLRDEDWVPRSV------RELARKIEEAIEELeqeLGREPTDEE-IAEELGISLEEVQEALEAANAYQLLSLDEPLE 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 189 DEDSFAPIDWLADHDSEPSRQLSKQAhyalqtegLQNALAQLDDRSRRIVESRWLQDdggLTLHQLAAEYGVSAERIRQI 268
Cdd:COG1191   154 DGDDLLDLLESGDPEEELEHEELREA--------LAEAIEQLPERERLVLSLYYFEE---LTLKEIAEVLGVSESRVSRL 222
                         250
                  ....*....|....
gi 1518349244 269 EAKAMQKLRGFLTE 282
Cdd:COG1191   223 HKKALARLREYLKE 236
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
28-277 3.28e-25

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 104.31  E-value: 3.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  28 PMLSQEEETRLAERrIKGDLNA---------------------------AK-QLILSHLRVVVSIARGYDGYGLNQADLI 79
Cdd:PRK05901  224 KLLNAEEEVELAKR-IEAGLYAeellaegekldpelrrdlqwigrdgkrAKnHLLEANLRLVVSLAKRYTNRGLSFLDLI 302
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  80 QEGNIGLMKAVKRYEPGRGARlFS-FAVHWIKAEIHEFILRNWRLVR-----VAT----TKPQRKLffnlrsmrknLNAL 149
Cdd:PRK05901  303 QEGNLGLIKAVEKFDYTKGYK-FStYATWWIRQAITRAMADQARTIRipvhmVETinklGRIEREL----------LQEL 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 150 ----SPKEaqdIADDLGVKLSEVLEMeQRMTGHDIAIMADNSDDEDSFapidwLAD--HDSE---PS-----RQLSKQAH 215
Cdd:PRK05901  372 grepTPEE---LAKEMGFTPEKVREI-QKYNREPISLDKTIGKEGDSQ-----FGDfiEDSEavsPVdavsfTLLQDQLQ 442
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518349244 216 YALQTeglqnalaqLDDRSRRIVESRW-LQDDGGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK05901  443 EVLET---------LSEREAGVIRMRFgLTDGQPKTLDEIGQVYGVTRERIRQIESKTLRKLR 496
PRK07921 PRK07921
RNA polymerase sigma factor SigB; Reviewed
33-277 3.98e-23

RNA polymerase sigma factor SigB; Reviewed


Pssm-ID: 181169 [Multi-domain]  Cd Length: 324  Bit Score: 96.72  E-value: 3.98e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  33 EEETRLAERRiKGDL-------NAAKQ-LILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSF 104
Cdd:PRK07921   64 ETRKRLSEAR-KRDLaavvrdgEAARRhLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTY 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 105 AVHWIKAEIHEFILRNWRLVR--VATTKPQRKLFFNLRSMRKNLNalspKEAQD--IADDLGV---KLSEVLEMEQRMTG 177
Cdd:PRK07921  143 ATWWIRQAITRGMADQSRTIRlpVHLVEQVNKLARIKRELHQQLG----REATDeeLAEESGIpeeKIADLLEHSRDPVS 218
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 178 HDiaiMADNSDDEdsfAPI-DWLAdhDSEPSRQLSKQAHYALQTEgLQNALAQLDDRSRRIVESRWLQDDG-GLTLHQLA 255
Cdd:PRK07921  219 LD---MPVGSDEE---APLgDFIE--DSEATSAENAVIAGLLHTD-IRSVLATLDEREQQVIRLRFGLDDGqPRTLDQIG 289
                         250       260
                  ....*....|....*....|..
gi 1518349244 256 AEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK07921  290 KLFGLSRERVRQIEREVMSKLR 311
PRK07598 PRK07598
RNA polymerase sigma factor SigC; Validated
40-277 1.12e-21

RNA polymerase sigma factor SigC; Validated


Pssm-ID: 236067 [Multi-domain]  Cd Length: 415  Bit Score: 93.78  E-value: 1.12e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  40 ERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILR 119
Cdd:PRK07598  167 EQIQKQGLRAKEHMIKANLRLVVSVAKKYQNRGLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAIAT 246
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 120 NWRLVR--VATT-------KPQRKLffnlrSMRKNLNAlspkEAQDIADDLGVKLSEVLEMEQRMTgHDIAIMADNSDDE 190
Cdd:PRK07598  247 QSRTIRlpVHITeklnkikKAQRKI-----SQEKGRTP----TIEDIAQELEMTPTQVREVLLRVP-RSVSLETKVGKDK 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 191 DSfAPIDWLADHDSEPSRQLSKQahyALQTEgLQNALAQLDDRSRRIVESRW-LQDDGGLTLHQLAAEYGVSAERIRQIE 269
Cdd:PRK07598  317 DT-ELGDLLETDDISPEEMLMRE---SLQRD-LQHLLADLTSRERDVIRMRFgLADGHTYSLAEIGRALDLSRERVRQIE 391

                  ....*...
gi 1518349244 270 AKAMQKLR 277
Cdd:PRK07598  392 SKALQKLR 399
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
41-277 1.60e-21

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 92.92  E-value: 1.60e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  41 RRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRN 120
Cdd:PRK07406  129 RRLMLGRRAKEKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQ 208
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 121 WRLVRVATtkpqrKLFFNLRSMRKNLNALSpkeaqdiaDDLGVKLSEVlEMEQR--MTGHDIAIMADNSD---------- 188
Cdd:PRK07406  209 SRTIRLPV-----HLYETISRIKKTTKVLS--------QEFGRKPTEE-EIAESmeMTIEKLRFIAKSAQlpisletpig 274
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 189 -DEDSfAPIDWLADHDSEPSRQLSKQahyaLQTEGLQNALAQLDDRSRRIVESRWLQDDGGL-TLHQLAAEYGVSAERIR 266
Cdd:PRK07406  275 kEEDS-RLGDFIEADGETPEDDVAKN----LLREDLEGVLATLSPRERDVLRLRYGLDDGRMkTLEEIGQIFNVTRERIR 349
                         250
                  ....*....|.
gi 1518349244 267 QIEAKAMQKLR 277
Cdd:PRK07406  350 QIEAKALRKLR 360
PRK05949 PRK05949
RNA polymerase sigma factor; Validated
34-277 3.38e-19

RNA polymerase sigma factor; Validated


Pssm-ID: 180321 [Multi-domain]  Cd Length: 327  Bit Score: 85.66  E-value: 3.38e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  34 EETRLaERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEI 113
Cdd:PRK05949   78 SETEL-KQTLKQGKRAKQKMIEANLRLVVAIAKKYQKRNMEFLDLIQEGTLGLERGVEKFDPTRGYKFSTYAYWWIRQAI 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 114 HEFILRNWRLVR--VATTKPQRKLFFNLRSMRKNL-NALSPKEaqdIADDLGVKLS---EVLEMEQRMTGHDIAImADNS 187
Cdd:PRK05949  157 TRAIAQQARTIRlpIHITEKLNKIKKTQRELSQKLgRSATPAE---IAKELELEPSqirEYLSMARQPISLDVRV-GDNQ 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 188 DDEDSfapiDWLADHDSEPSRQLSKQahyaLQTEGLQNALAQLDDRSRRIVESRW-LQDDGGLTLHQLAAEYGVSAERIR 266
Cdd:PRK05949  233 DTELS----ELLEDEGPSPDQYITQE----LLRQDLNNLLAELTPQQREVLTLRFgLEDGKELSLAKVGERLNLSRERVR 304
                         250
                  ....*....|.
gi 1518349244 267 QIEAKAMQKLR 277
Cdd:PRK05949  305 QLEHQALAHLR 315
PRK05803 PRK05803
RNA polymerase sporulation sigma factor SigK;
20-276 1.50e-18

RNA polymerase sporulation sigma factor SigK;


Pssm-ID: 180266 [Multi-domain]  Cd Length: 233  Bit Score: 82.30  E-value: 1.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  20 YIhTVNSIPM-LSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRG 98
Cdd:PRK05803   21 YV-KNNSFPQpLSEEEERKYLELMKEGDEEARNILIERNLRLVAHIVKKFENTGEDVDDLISIGTIGLIKAIESFDAGKG 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  99 ARLFSFAVHWIKAEIhefilrnwrlvrvattkpqrklFFNLRSMRKNLNALSpkeaqdIADDLGVklsevlEMEqrmtGH 178
Cdd:PRK05803  100 TKLATYAARCIENEI----------------------LMHLRNLKKTKKEVS------LQDPIGV------DKE----GN 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 179 DIAIMADNSDDEDSfapidwladhdsepsrqLSKQAHYALQTEGLQNALAQLDDRSRRIVESRW-LQDDGGLTLHQLAAE 257
Cdd:PRK05803  142 EISLIDILGSEEDD-----------------VIEQVELKMEVEKLYKKIDILDEREKEVIEMRYgLGNGKEKTQREIAKA 204
                         250
                  ....*....|....*....
gi 1518349244 258 YGVSAERIRQIEAKAMQKL 276
Cdd:PRK05803  205 LGISRSYVSRIEKRALKKL 223
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
27-280 2.54e-17

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 79.22  E-value: 2.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  27 IPMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAV 106
Cdd:PRK08215   16 LPVLKNEEMRELFERMQNGDKEAREKLINGNLRLVLSVIQRFNNRGENVDDLFQVGCIGLMKAIDNFDLSQNVKFSTYAV 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 107 HWIKAEIHEFiLRNWRLVRVatTKPQRKLFFNLRSMRKNLNALSPKE--AQDIADDLGVKLSEVlemeqrmtghdiaIMA 184
Cdd:PRK08215   96 PMIIGEIRRY-LRDNNPIRV--SRSLRDIAYKALQVREKLINENSKEptVEEIAKELEVPREEV-------------VFA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 185 -DNSDDEDS-FAPI-----------DWLADHDSEPSRQLSKQAhyalqtegLQNALAQLDDRSRRIVESRWLQddgGLTL 251
Cdd:PRK08215  160 lDAIQDPVSlFEPIyhdggdpiyvmDQISDEKNKDENWLEEIA--------LKEAMKKLNDREKLILNLRFFQ---GKTQ 228
                         250       260
                  ....*....|....*....|....*....
gi 1518349244 252 HQLAAEYGVSAERIRQIEAKAMQKLRGFL 280
Cdd:PRK08215  229 MEVAEEIGISQAQVSRLEKAALKHMRKYI 257
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
77-285 3.10e-16

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 76.50  E-value: 3.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  77 DLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEF---------ILRNWRLVRVATTKPQRKLffnlrsmRKNLN 147
Cdd:PRK07408   55 DLVQVGSLGLIRAIERFDPSKGHAFSSFAIPYIRGEIQHYlrdksptvrIPRRWQELQRQAKKVRQEL-------RQELG 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 148 AlSPKEaQDIADDLGVKLSEVLEME----QRMTGHDIAIMADNSDDEDSFApiDWLADHDSePSRQLSKQAHyaLQtegL 223
Cdd:PRK07408  128 R-QPTD-QEIAQALDISLEEWQEIKlalqNRTPLSLDAPVNQDEDGSTSLG--DLLPDPRY-RSFQLAQEDR--IR---L 197
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518349244 224 QNALAQLDDRSRRIVESRWLQDdggLTLHQLAAEYGVSAERI-RQIEaKAMQKLRGFLTEEAE 285
Cdd:PRK07408  198 QQALAQLEERTREVLEFVFLHD---LTQKEAAERLGISPVTVsRRVK-KGLDQLKKLLQPEDD 256
PRK05572 PRK05572
RNA polymerase sporulation sigma factor, SigF/SigG family;
28-282 3.88e-16

RNA polymerase sporulation sigma factor, SigF/SigG family;


Pssm-ID: 180137 [Multi-domain]  Cd Length: 252  Bit Score: 76.16  E-value: 3.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  28 PMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVH 107
Cdd:PRK05572   12 PQLKDEENKELIKKSQDGDQEARDTLVEKNLRLVWSVVQRFLNRGYEPDDLFQIGCIGLLKAVDKFDLSYDVKFSTYAVP 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 108 WIKAEIHEFiLRNWRLVRVATTKPQ--RKLFFNLRSMRKNLNAlSPKeAQDIADDLGVKLSEVLemeqrmtghdIAIMAD 185
Cdd:PRK05572   92 MIIGEIQRF-LRDDGTVKVSRSLKEtaNKIRKDKDELSKELGR-EPT-IEELAEYLGVTPEEVV----------LAQEAS 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 186 NS----------DDEDSFAPIDWLADHDSEpsRQLSKQAhyalqtegLQNALAQLDDRSRRIVESRWLQDDgglTLHQLA 255
Cdd:PRK05572  159 RSpqsihetvheNDGDPITLLDQIADQSEE--DWFDKIA--------LKEAIRELDERERLIVYLRYFKDK---TQSEVA 225
                         250       260
                  ....*....|....*....|....*..
gi 1518349244 256 AEYGVSAERIRQIEAKAMQKLRGFLTE 282
Cdd:PRK05572  226 KRLGISQVQVSRLEKKILKQMKEKLDE 252
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
53-122 5.11e-16

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 71.08  E-value: 5.11e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  53 LILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWR 122
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
PRK07405 PRK07405
RNA polymerase sigma factor SigD; Validated
49-277 7.06e-16

RNA polymerase sigma factor SigD; Validated


Pssm-ID: 180963 [Multi-domain]  Cd Length: 317  Bit Score: 76.34  E-value: 7.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  49 AAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRV-- 126
Cdd:PRK07405   82 AKRKMVEANLRLVVSVAKKYLKRNVDLLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKSRTIRLpi 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 127 -------ATTKPQRKLffnlrSMRKNLNALSPKEAQDIadDLGVK-LSEVLEMEQRMTGHDIAImADNSDDEDSfapiDW 198
Cdd:PRK07405  162 hiteklnKIKKAQRQL-----SQQLGRAATIGELAEEL--ELTPKqVREYLERARQPLSLDLRV-GDNQDTELG----EL 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 199 LADHDSEPSrqlSKQAHYALQTEgLQNALAQLDDRSRRIVESRWLQDDG-GLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK07405  230 LEDTGASPE---DFATQSSLQLD-LERLMEDLTPQQKEVIALRFGLEDGqPLTLAKIGERLNISRERVRQIEREALSKLR 305
PRK05658 PRK05658
RNA polymerase sigma factor RpoD; Validated
48-277 1.79e-14

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 235549 [Multi-domain]  Cd Length: 619  Bit Score: 73.29  E-value: 1.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  48 NAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARlFS-FAVHWIKAEI------------- 113
Cdd:PRK05658  380 RAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYK-FStYATWWIRQAItrsiadqartiri 458
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 114 --H--EFIlrNwRLVRVattkpqrklffnlrsMRKNLNALSpKEAQD--IADDLGV---KLSEVLEmeqrmtghdIA--- 181
Cdd:PRK05658  459 pvHmiETI--N-KLNRI---------------SRQMLQEIG-REPTPeeLAERLGMpedKVRKVLK---------IAkep 510
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 182 ------ImadnSDDEDS----F-------APIDwladhdsepsrqlskqahYALQtEGLQNA----LAQLDDRSRRIVES 240
Cdd:PRK05658  511 isletpI----GDDEDShlgdFiedknaeLPID------------------AAIQ-ESLREAttdvLASLTPREAKVLRM 567
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1518349244 241 RW-LQDDGGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK05658  568 RFgIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLR 605
PRK08301 PRK08301
RNA polymerase sporulation sigma factor SigE;
28-277 8.63e-14

RNA polymerase sporulation sigma factor SigE;


Pssm-ID: 236228 [Multi-domain]  Cd Length: 234  Bit Score: 69.11  E-value: 8.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  28 PMLSQEEETRLAERRIKGDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVH 107
Cdd:PRK08301   32 PPLSKEEEEYLLNKLPKGDEAVRSLLIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTFNPEKKIKLATYASR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 108 WIKAEIHEFILRNwrlvrvattkpqrklffnlrsmRKNLNALSPKEAQDIADDlG--VKLSEVLEMEQRMTGHDIaimad 185
Cdd:PRK08301  112 CIENEILMYLRRN----------------------NKVKAEVSFDEPLNIDWD-GneLLLSDVLGTDNDIIYKDI----- 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 186 nsddedsfapidwladhDSEPSRQLskqahyalqtegLQNALAQLDDRSRRIVESRW-LQDDGGLTLHQLAAEYGVSAER 264
Cdd:PRK08301  164 -----------------EDEVDRKL------------LKKALKKLSDREKQIMELRFgLNGGEEKTQKEVADMLGISQSY 214
                         250
                  ....*....|...
gi 1518349244 265 IRQIEAKAMQKLR 277
Cdd:PRK08301  215 ISRLEKRIIKRLK 227
PRK07122 PRK07122
RNA polymerase sigma factor SigF; Reviewed
64-277 1.65e-13

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 168831 [Multi-domain]  Cd Length: 264  Bit Score: 68.65  E-value: 1.65e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  64 IARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVattkPQRklffnLRSMR 143
Cdd:PRK07122   56 IARRFDGRGEPRDDLVQVARVGLVNAVNRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSVKV----PRR-----LKELH 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 144 KNLNALSPKEAQ---------DIADDLGVKLSEVLE-MEQRMTGHDIAIMA-DNSDDEDSFAPIDWLADHDSEPSRQLSK 212
Cdd:PRK07122  127 LRLGRATAELSQrlgraptasELAAELGMDREEVVEgLVAGSAYNTLSIDSgGGSGDDDARAIADTLGDVDAGLDQIENR 206
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1518349244 213 qahyalqtEGLQNALAQLDDRSRRIVESRWLqddGGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:PRK07122  207 --------EALRPLLAALPERERTVLVLRFF---ESMTQTQIAERVGISQMHVSRLLAKTLARLR 260
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
226-277 4.09e-12

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 59.75  E-value: 4.09e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1518349244 226 ALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGE---GLTLEEIGERLGISRERVRQIEKRALRKLR 49
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
77-281 1.32e-11

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 63.48  E-value: 1.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  77 DLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEfILRNWRLVRVATTKPQRKLFFNLRSMRKNLNalspKEAQD 156
Cdd:PRK05911   55 DLYASGVEGLVRAVERFDPEKSRRFEGYALFLIKAAIID-DLRKQDWVPRSVHQKANKLADAMDSLRQSLG----KEPTD 129
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 157 IaddlgvKLSEVLEMEQRMTGHDIA------IMADN------SDDEDSFAPIDWLADHDSEPSRQLSKQAHYALQtegLQ 224
Cdd:PRK05911  130 G------ELCEYLNISQQELSGWFSsarpalILSLNeefpcqSDDEAGLALEERIADERAETGYDVVDKKEFSSI---LA 200
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1518349244 225 NALAQLDDRSRRIVESRWLQDdggLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFLT 281
Cdd:PRK05911  201 EAILALEEKERKVMALYYYEE---LVLKEIGKILGVSESRVSQIHSKALLKLRATLS 254
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
26-282 1.78e-11

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 63.17  E-value: 1.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  26 SIPMLSQEEETRL-AERRIKGDLNAAKQLILSHLRVVVSIArGYDGYGL----NQADLIQEGNIGLMKAVKRYEPGRGAR 100
Cdd:PRK06288    8 KIPKYAQQDETELwREYKKTGDPKIREYLILKYSPLVKYVA-GRIAVGMpqnvEFDDLVSYGVFGLIDAIEKFDPEREIK 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 101 LFSFAVHWIKAEIHEFiLR--NW--RLVRvattkPQRKLFFNLRSMRKNLNALSPKEaQDIADDLGVKLSEVLEMEQRMT 176
Cdd:PRK06288   87 FKTYAVTRIRGAIFDE-LRsiDWipRSVR-----QKARQIERAIAMLEARLGRTPSD-EEIADELGISLEEYNSLLSKLS 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 177 GHDIAIMAD---NSDDEDSFAPIDWLADHDSEpsrqlskQAHYALQTEGLQN----ALAQLDDRSRRIVESRWLQDdggL 249
Cdd:PRK06288  160 GTSVVSLNDlwfGGDEGDEVSLMDTLESPAAL-------NPDEIAEREEIKRviveAIKTLPEREKKVLILYYYED---L 229
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1518349244 250 TLHQLAAEYGVSAERIRQIEAKAMQKLRGFLTE 282
Cdd:PRK06288  230 TLKEIGKVLGVTESRISQLHTKAVLQLRAKLAE 262
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
48-280 3.97e-11

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 60.05  E-value: 3.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  48 NAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPgrGARLFSFAVHWIKAEIHEFilrnwrlvrva 127
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDP--EGSFKAWLFRIARNLILDY----------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 128 ttkpqrklffnLRSMRKNlnalspkeaqdiaddlgvklsevlemeqRMTGHDIAIMADNSDDEDSfapidwladhdseps 207
Cdd:TIGR02937  68 -----------LRRKRRL----------------------------RRELDLLEELLDSDPSPEE--------------- 93
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1518349244 208 rqlskQAHYALQTEGLQNALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFL 280
Cdd:TIGR02937  94 -----ELEQEEEREALREALEKLPEREREVLVLRYLE---GLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
45-284 6.09e-11

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 61.25  E-value: 6.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  45 GDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFIL-RNWRl 123
Cdd:PRK08583   26 QDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGRSFEAFAVPTIIGEIKRYLRdKTWS- 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 124 VRVattkPQR--KLFFNLRSMRKNLNA---LSPKeAQDIADDLGVKLSEVLE-MEQ----RMTGHDIAIMADNsdDEDSF 193
Cdd:PRK08583  105 VHV----PRRikELGPKIKKAVDELTTelqRSPK-ISEIADRLGVSEEEVLEaMEMgksyQALSVDHSIEADS--DGSTV 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 194 APIDWLAdhdsepsrqlSKQAHYAL--QTEGLQNALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAK 271
Cdd:PRK08583  178 TLLDIVG----------QQEDGYELteQRMILEKILPVLSDREKSIIQCTFIE---NLSQKETGERLGISQMHVSRLQRQ 244
                         250
                  ....*....|...
gi 1518349244 272 AMQKLRGFLTEEA 284
Cdd:PRK08583  245 AIKKLREAAFLDT 257
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
223-277 9.20e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 53.26  E-value: 9.20e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1518349244 223 LQNALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAKAMQKLR 277
Cdd:cd06171     4 LEEALDKLPEREREVILLRFGE---GLSYEEIAEILGISRSTVRQRLHRALKKLR 55
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
77-282 4.07e-09

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 55.62  E-value: 4.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  77 DLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRN-W--RLVRvattKPQRKLFFNLRSMRKNLNAlSPKE 153
Cdd:PRK06986   40 DLIQAGMIGLLEAARRYDGEQGASFETYAGQRIRGAMLDELRSLdWvpRSVR----RNAREVAQAIRQLEQELGR-EPTD 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 154 AQdIADDLGVKLSEVLEMEQRMTGHDIAIMAD-NSDDEDSFAPIDwlADHDSEPSRQLSKQahyALQtEGLQNALAQLDD 232
Cdd:PRK06986  115 TE-VAEKLGLSLEEYREMLLDTNISQLFSIDElRGEHGDSILVTE--DHQDEDPLQQLEDE---ELR-EALVEAIESLPE 187
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1518349244 233 RSRRIVEsrwLQDDGGLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFLTE 282
Cdd:PRK06986  188 REQLVLS---LYYQEELNLKEIGAVLGVSESRVSQIHSQAIKRLRARLGE 234
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
29-117 1.28e-06

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 47.98  E-value: 1.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  29 MLSQEEETRLAERrIKGDLNAAKQLILSHLR-VVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLFSFAVH 107
Cdd:PRK08295    5 DYDELEDEELVEL-ARSGDKEALEYLIEKYKnFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKDKLSSFKSFAEL 83
                          90
                  ....*....|
gi 1518349244 108 WIKAEIHEFI 117
Cdd:PRK08295   84 CITRQIITAI 93
PRK12427 PRK12427
FliA/WhiG family RNA polymerase sigma factor;
73-280 2.60e-06

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 183523 [Multi-domain]  Cd Length: 231  Bit Score: 47.55  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  73 LNQADLIQEGNIGLMKAVKRY-EPGRGarLFSFAVHWIKAEI-HEFILRNWRLVRVATTKPQRKLFfnLRSMRKNLNalS 150
Cdd:PRK12427   43 IDREDMEQIALMGLLEALRRYgHPDEQ--FAAYAVHRIRGAIlDELRELDWRPRRLRQKTHKTNDA--IREIAKRLG--H 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 151 PKEAQDIADDLGVKLSEVLEMEQRMTGHDIAIMADNSDDEDSFAPIDwladhdsepSRQLSKQAhyaLQTEGLQNALAQL 230
Cdd:PRK12427  117 EPNFEEISAELNLTAEEYQEYLLLENAGTLESLDELLALEAHNDILQ---------SRDLEENI---IIEDNLKQALSQL 184
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1518349244 231 DDRSRRIVESRWLQDdggLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFL 280
Cdd:PRK12427  185 DEREQLILHLYYQHE---MSLKEIALVLDLTEARICQLNKKIAQKIKSFF 231
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
77-280 4.30e-04

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 40.80  E-value: 4.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244  77 DLIQEGNIGLMKAVKRYEPGRGARLFSFAVHWIKAEIHEFILRNWRLVRVATTKPQR------KLffNLRSMRknlnALS 150
Cdd:PRK07670   54 DLKSLGMLGLYDALEKFDPSRDLKFDTYASFRIRGAIIDGLRKEDWLPRSMREKTKKveaaieKL--EQRYMR----NVT 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 151 PKEaqdIADDLGVKLSEV------------LEMEQRMTGHDiaimadnSDDEDSFAPIDwlaDHDSEPSRQLSKQAhyal 218
Cdd:PRK07670  128 PKE---VAAELGMTEEEVeatmnegffanlLSIDEKTHDQD-------DGENVSVTIRD---DKTPTPEEKLLKEE---- 190
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1518349244 219 QTEGLQNALAQLDDRsRRIVESRWLQDDggLTLHQLAAEYGVSAERIRQIEAKAMQKLRGFL 280
Cdd:PRK07670  191 LIEELAEKIKQLSEK-EQLVISLFYKEE--LTLTEIGQVLNLSTSRISQIHSKALFKLKKLL 249
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
195-286 5.75e-04

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 39.98  E-value: 5.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1518349244 195 PIDWLADHDSEPSRQLSKQAHYALqtegLQNALAQLDDRSRRIVESRWLQddgGLTLHQLAAEYGVSAERIRQIEAKAMQ 274
Cdd:COG1595    97 LAEELPDEAADPEEALEAEELLEA----LLAALERLPPRQREVLVLRYLE---GLSYAEIAEILGISEGTVKSRLSRARK 169
                          90
                  ....*....|..
gi 1518349244 275 KLRGFLTEEAEA 286
Cdd:COG1595   170 KLREALEEEGAL 181
Sigma70_r1_2 pfam00140
Sigma-70 factor, region 1.2;
16-46 1.55e-03

Sigma-70 factor, region 1.2;


Pssm-ID: 425482 [Multi-domain]  Cd Length: 34  Bit Score: 35.36  E-value: 1.55e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1518349244  16 SLEQYIHTVNSIPMLSQEEETRLAERRIKGD 46
Cdd:pfam00140   2 SVRLYLKEIGRIPLLTAEEEVELAKRIEAGD 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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