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Conserved domains on  [gi|1508602860|gb|RMZ84397|]
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hypothetical protein DV738_g755, partial [Chaetothyriales sp. CBS 135597]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 1197-1292 2.65e-31

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


:

Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 118.08  E-value: 2.65e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860 1197 DALKGVLKIALIHDGLARGLREASKALDRRQAHMCVLNEACEEEAYKKLVVALCQEHKIPLIKVPDGKQLGEWAGLCVLd 1276
Cdd:pfam01248    1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                           90
                   ....*....|....*.
gi 1508602860 1277 REGNARKVVNCSCVVV 1292
Cdd:pfam01248   80 VSALAIKDEGDSKILV 95
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-464 1.44e-30

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 122.76  E-value: 1.44e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666    116 RDKDGETPLHLAAYNGNLEIVK-LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAA 194

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEEPYELvpSDDENYKTIRKLIANAKEQEYPKRRRSNDKRDDDASSRGA 464
Cdd:COG0666    195 ENGHLEIVKLLLEAGADVNAKDNDGKTALDL--AAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAA 265
Ank_4 pfam13637
Ankyrin repeats (many copies);
535-594 3.59e-06

Ankyrin repeats (many copies);


:

Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 45.34  E-value: 3.59e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  535 ESESVVAAAKAGHEEVLQYLLAMGeADPDPPPLSGlpqgyNTPILAAIGRGNLDVIRLLV 594
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKG-ADINAVDGNG-----ETALHFAASNGNVEVLKLLL 54
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 687-867 1.71e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  687 KSPRSATKDRKRSDiSPPNSDRRSTLAAYDDADSvavSSDQDRSVPQGKSDKHRSQSDPHTTAESEV--EPAQRRRRlmt 764
Cdd:PTZ00449   495 KLAPIEEEDSDKHD-EPPEGPEASGLPPKAPGDK---EGEEGEHEDSKESDEPKEGGKPGETKEGEVgkKPGPAKEH--- 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  765 gkdyrKQGRKHSATSGPRGDESGHEEKRESQAPGLKRARD-SFSQSPESSKEPESrVKVKKRRTIPESPEESHVGLPPRK 843
Cdd:PTZ00449   568 -----KPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSaQRPTRPKSPKLPEL-LDIPKSPKRPESPKSPKRPPPPQR 641

                          170       180
                   ....*....|....*....|....
gi 1508602860  844 PSKPSEPQDAEMKDVKAPPPSNVP 867
Cdd:PTZ00449   642 PSSPERPEGPKIIKSPKPPKSPKP 665
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 1197-1292 2.65e-31

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 118.08  E-value: 2.65e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860 1197 DALKGVLKIALIHDGLARGLREASKALDRRQAHMCVLNEACEEEAYKKLVVALCQEHKIPLIKVPDGKQLGEWAGLCVLd 1276
Cdd:pfam01248    1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                           90
                   ....*....|....*.
gi 1508602860 1277 REGNARKVVNCSCVVV 1292
Cdd:pfam01248   80 VSALAIKDEGDSKILV 95
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-464 1.44e-30

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 122.76  E-value: 1.44e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666    116 RDKDGETPLHLAAYNGNLEIVK-LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAA 194

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEEPYELvpSDDENYKTIRKLIANAKEQEYPKRRRSNDKRDDDASSRGA 464
Cdd:COG0666    195 ENGHLEIVKLLLEAGADVNAKDNDGKTALDL--AAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAA 265
Ank_2 pfam12796
Ankyrin repeats (3 copies);
320-409 9.19e-20

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 85.17  E-value: 9.19e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  320 LSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLsNNAEVDTRNiDKDTPLIDAVENGHVEVV 399
Cdd:pfam12796    1 LHLAAKNGNLELVK-LLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL-EHADVNLKD-NGRTALHYAARSGHLEIV 77

                           90
                   ....*....|
gi 1508602860  400 KLLLDHGANP 409
Cdd:pfam12796   78 KLLLEKGADI 87
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 312-408 1.08e-13

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 75.00  E-value: 1.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKVYLKERPDdLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:PHA02874   120 KDAELKTFLHYAIKKGDLESIKMLFEYGAD-VNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAA 198

                           90
                   ....*....|....*..
gi 1508602860  392 ENGHVEVVKLLLDHGAN 408
Cdd:PHA02874   199 EYGDYACIKLLIDHGNH 215
TRPV5-6 cd22192
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...
 316-413 1.71e-07

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.


Pssm-ID: 411976 [Multi-domain]  Cd Length: 609  Bit Score: 55.79  E-value: 1.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  316 GRTFLSRACNNDDLEKAKVYLKERPDDLDLPDN----AGNTPLQIAALEGFVDIVKFLLSNNAEVDT---------RNID 382
Cdd:cd22192     51 GETALHVAALYDNLEAAVVLMEAAPELVNEPMTsdlyQGETALHIAVVNQNLNLVRELIARGADVVSpratgtffrPGPK 130

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1508602860  383 K-----DTPLIDAVENGHVEVVKLLLDHGANPR----LGN 413
Cdd:cd22192    131 NliyygEHPLSFAACVGNEEIVRLLIEHGADIRaqdsLGN 170
Ank_4 pfam13637
Ankyrin repeats (many copies);
535-594 3.59e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 45.34  E-value: 3.59e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  535 ESESVVAAAKAGHEEVLQYLLAMGeADPDPPPLSGlpqgyNTPILAAIGRGNLDVIRLLV 594
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKG-ADINAVDGNG-----ETALHFAASNGNVEVLKLLL 54
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 382-409 3.98e-06

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 44.50  E-value: 3.98e-06
                            10        20
                    ....*....|....*....|....*...
gi 1508602860   382 DKDTPLIDAVENGHVEVVKLLLDHGANP 409
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
PHA03095 PHA03095
ankyrin-like protein; Provisional
 342-591 1.71e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 48.87  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  342 DLDLPDNAGNTPLQIAALEGFV-DIVKFLLSNNAEVDTRNIDKDTPL--IDAVENGHVEVVKLLLDHGANPRLGNAKGEE 418
Cdd:PHA03095    75 DVNAPERCGFTPLHLYLYNATTlDVIKLLIKAGADVNAKDKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMT 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  419 PYE-LVPSDDENYKTIRKLIAnakeqeypkrrRSNDKRDDDASSRGA---SANSPRESPGpmvgprspppYLSSRRRTGR 494
Cdd:PHA03095   155 PLAvLLKSRNANVELLRLLID-----------AGADVYAVDDRFRSLlhhHLQSFKPRAR----------IVRELIRAGC 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  495 SEVTRNDL----LWQANTQENLRR------LAAKGDVqgvtQVLNILGKAeseSVVAAAKAGHEEVLQYLLAMGeADPDP 564
Cdd:PHA03095   214 DPAATDMLgntpLHSMATGSSCKRslvlplLIAGISI----NARNRYGQT---PLHYAAVFNNPRACRRLIALG-ADINA 285

                          250       260
                   ....*....|....*....|....*..
gi 1508602860  565 PPLSGlpqgyNTPILAAIGRGNLDVIR 591
Cdd:PHA03095   286 VSSDG-----NTPLSLMVRNNNGRAVR 307
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 1211-1285 1.83e-05

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 44.76  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860 1211 GLAR-------GLREASKALDRRQAHMCVLNEACEEEAYKKLVvALCQEHKIPLIKVPDGKQLGEWAG------LCVLDr 1277
Cdd:COG1358      8 GLARragklvsGEEQVLKAIRKGKAKLVIIAEDASENTKKKLL-DLCEEYGVPVVEVGTKEELGKAIGkvgravVAITD- 85


                   ....*...
gi 1508602860 1278 EGNARKVV 1285
Cdd:COG1358     86 EGFAKKLL 93
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 687-867 1.71e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  687 KSPRSATKDRKRSDiSPPNSDRRSTLAAYDDADSvavSSDQDRSVPQGKSDKHRSQSDPHTTAESEV--EPAQRRRRlmt 764
Cdd:PTZ00449   495 KLAPIEEEDSDKHD-EPPEGPEASGLPPKAPGDK---EGEEGEHEDSKESDEPKEGGKPGETKEGEVgkKPGPAKEH--- 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  765 gkdyrKQGRKHSATSGPRGDESGHEEKRESQAPGLKRARD-SFSQSPESSKEPESrVKVKKRRTIPESPEESHVGLPPRK 843
Cdd:PTZ00449   568 -----KPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSaQRPTRPKSPKLPEL-LDIPKSPKRPESPKSPKRPPPPQR 641

                          170       180
                   ....*....|....*....|....
gi 1508602860  844 PSKPSEPQDAEMKDVKAPPPSNVP 867
Cdd:PTZ00449   642 PSSPERPEGPKIIKSPKPPKSPKP 665
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 1197-1292 2.65e-31

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 118.08  E-value: 2.65e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860 1197 DALKGVLKIALIHDGLARGLREASKALDRRQAHMCVLNEACEEEAYKKLVVALCQEHKIPLIKVPDGKQLGEWAGLCVLd 1276
Cdd:pfam01248    1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                           90
                   ....*....|....*.
gi 1508602860 1277 REGNARKVVNCSCVVV 1292
Cdd:pfam01248   80 VSALAIKDEGDSKILV 95
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-464 1.44e-30

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 122.76  E-value: 1.44e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666    116 RDKDGETPLHLAAYNGNLEIVK-LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAA 194

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEEPYELvpSDDENYKTIRKLIANAKEQEYPKRRRSNDKRDDDASSRGA 464
Cdd:COG0666    195 ENGHLEIVKLLLEAGADVNAKDNDGKTALDL--AAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAA 265
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-419 7.02e-28

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 115.05  E-value: 7.02e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666     83 KDDGGNTLLHAAARNGDLEIVK-LLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAA 161

                           90       100
                   ....*....|....*....|....*...
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEEP 419
Cdd:COG0666    162 ANGNLEIVKLLLEAGADVNARDNDGETP 189
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-441 1.20e-22

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 99.64  E-value: 1.20e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666    149 QDNDGNTPLHLAAANGNLEIVK-LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAA 227

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEEPYELVPSDDENYKTIRKLIANAK 441
Cdd:COG0666    228 ENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLL 277
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
313-640 3.46e-21

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 95.41  E-value: 3.46e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  313 DKNGRTFLSRACNNDDLEKAKVYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVE 392
Cdd:COG0666     50 ADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAY 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  393 NGHVEVVKLLLDHGANPRLGNAKGEEPyelvpsddenyktirkLIAnakeqeypkrrrsndkrdddassrgASANspres 472
Cdd:COG0666    130 NGNLEIVKLLLEAGADVNAQDNDGNTP----------------LHL-------------------------AAAN----- 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  473 pgpmvgprspppylssrrrtGRSEVTRndLLwqantqenlrrLAAKGDVqgvtqvlNILGKAESESVVAAAKAGHEEVLQ 552
Cdd:COG0666    164 --------------------GNLEIVK--LL-----------LEAGADV-------NARDNDGETPLHLAAENGHLEIVK 203

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  553 YLLAMGeADPDPPPLSGlpqgyNTPILAAIGRGNLDVIRLLVEQSRFDPTRRFNKKTYFQIALERKGENWQREYELLKEA 632
Cdd:COG0666    204 LLLEAG-ADVNAKDNDG-----KTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLL 277


                   ....*...
gi 1508602860  633 YDKYAPNK 640
Cdd:COG0666    278 LAAALLDL 285
Ank_2 pfam12796
Ankyrin repeats (3 copies);
320-409 9.19e-20

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 85.17  E-value: 9.19e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  320 LSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLsNNAEVDTRNiDKDTPLIDAVENGHVEVV 399
Cdd:pfam12796    1 LHLAAKNGNLELVK-LLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL-EHADVNLKD-NGRTALHYAARSGHLEIV 77

                           90
                   ....*....|
gi 1508602860  400 KLLLDHGANP 409
Cdd:pfam12796   78 KLLLEKGADI 87
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 312-408 1.08e-13

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 75.00  E-value: 1.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKVYLKERPDdLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:PHA02874   120 KDAELKTFLHYAIKKGDLESIKMLFEYGAD-VNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAA 198

                           90
                   ....*....|....*..
gi 1508602860  392 ENGHVEVVKLLLDHGAN 408
Cdd:PHA02874   199 EYGDYACIKLLIDHGNH 215
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
312-418 5.36e-12

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 68.06  E-value: 5.36e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAV 391
Cdd:COG0666    182 RDNDGETPLHLAAENGHLEIVK-LLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAA 260

                           90       100
                   ....*....|....*....|....*..
gi 1508602860  392 ENGHVEVVKLLLDHGANPRLGNAKGEE 418
Cdd:COG0666    261 AAGAALIVKLLLLALLLLAAALLDLLT 287
Ank_2 pfam12796
Ankyrin repeats (3 copies);
310-380 3.86e-10

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 57.82  E-value: 3.86e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1508602860  310 KFRDKNGRTFLSRACNNDDLEKAKvYLKERPDdLDLPDNaGNTPLQIAALEGFVDIVKFLLSNNAEVDTRN 380
Cdd:pfam12796   24 NLQDKNGRTALHLAAKNGHLEIVK-LLLEHAD-VNLKDN-GRTALHYAARSGHLEIVKLLLEKGADINVKD 91
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
310-596 5.22e-10

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 62.28  E-value: 5.22e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  310 KFRDKNGRTFLSRACNNDDLEKAKVYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLID 389
Cdd:COG0666     14 ALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  390 AVENGHVEVVKLLLDHGANPRLGNAKGEEPyelvpsddenyktirklianakeqeypkrrrsndkrdddassrgasansp 469
Cdd:COG0666     94 AARNGDLEIVKLLLEAGADVNARDKDGETP-------------------------------------------------- 123

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  470 respgpmvgprspppylssrrrtgrsevtrndLLWqantqenlrrlaakgdvqgvtqvlnilgkaesesvvaAAKAGHEE 549
Cdd:COG0666    124 --------------------------------LHL-------------------------------------AAYNGNLE 134

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1508602860  550 VLQYLLAMGeADPDPPPLSGlpqgyNTPILAAIGRGNLDVIRLLVEQ 596
Cdd:COG0666    135 IVKLLLEAG-ADVNAQDNDG-----NTPLHLAAANGNLEIVKLLLEA 175
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 324-408 7.03e-10

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 62.76  E-value: 7.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  324 CNNDDLE--------KAKVYLKERPD-------DLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLI 388
Cdd:PHA03100   151 SNKIDLKilkllidkGVDINAKNRVNyllsygvPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLH 230

                           90       100
                   ....*....|....*....|
gi 1508602860  389 DAVENGHVEVVKLLLDHGAN 408
Cdd:PHA03100   231 IAILNNNKEIFKLLLNNGPS 250
Ank_4 pfam13637
Ankyrin repeats (many copies);
350-403 1.17e-09

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 54.97  E-value: 1.17e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1508602860  350 GNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLL 403
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 314-409 9.22e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 59.23  E-value: 9.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  314 KNGRTFLSRACNNDDLEKAKVYLKeRPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVEN 393
Cdd:PHA02875   100 KDGMTPLHLATILKKLDIMKLLIA-RGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAK 178

                           90
                   ....*....|....*.
gi 1508602860  394 GHVEVVKLLLDHGANP 409
Cdd:PHA02875   179 GDIAICKMLLDSGANI 194
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 318-449 9.20e-08

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 56.21  E-value: 9.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  318 TFLSRACN-----NDDLEKAKVYLKERPDDLDLpdnagntpLQIAALEGfVDI-----VKFLLSNNAEVDTRNIDKDTPL 387
Cdd:PHA03100   126 YLLDNGANvniknSDGENLLHLYLESNKIDLKI--------LKLLIDKG-VDInaknrVNYLLSYGVPINIKDVYGFTPL 196

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1508602860  388 IDAVENGHVEVVKLLLDHGANPRLGNAKGEEPYELvpSDDENYKTIRKLIANAKEQEYPKRR 449
Cdd:PHA03100   197 HYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHI--AILNNNKEIFKLLLNNGPSIKTIIE 256
TRPV5-6 cd22192
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...
 316-413 1.71e-07

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.


Pssm-ID: 411976 [Multi-domain]  Cd Length: 609  Bit Score: 55.79  E-value: 1.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  316 GRTFLSRACNNDDLEKAKVYLKERPDDLDLPDN----AGNTPLQIAALEGFVDIVKFLLSNNAEVDT---------RNID 382
Cdd:cd22192     51 GETALHVAALYDNLEAAVVLMEAAPELVNEPMTsdlyQGETALHIAVVNQNLNLVRELIARGADVVSpratgtffrPGPK 130

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1508602860  383 K-----DTPLIDAVENGHVEVVKLLLDHGANPR----LGN 413
Cdd:cd22192    131 NliyygEHPLSFAACVGNEEIVRLLIEHGADIRaqdsLGN 170
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 350-449 3.20e-07

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 54.23  E-value: 3.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  350 GNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGANPRLGNAKGEEPYeLVPSDDEN 429
Cdd:PHA02875   102 GMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPL-IIAMAKGD 180

                           90       100
                   ....*....|....*....|
gi 1508602860  430 YKTIRKLIANAKEQEYPKRR 449
Cdd:PHA02875   181 IAICKMLLDSGANIDYFGKN 200
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 366-545 6.40e-07

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 53.75  E-value: 6.40e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  366 VKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGANPRLGNAKGEEPYELvpSDDENYKTIRKLI-------- 437
Cdd:PTZ00322    98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLEL--AEENGFREVVQLLsrhsqchf 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  438 ---ANAKEQEYpkrrrsnDKRDDDASSRGASANSPRES--PGPMVGPRSPPPY-LSSRRRTGRSEVTRNDLLWQANT--- 508
Cdd:PTZ00322   176 elgANAKPDSF-------TGKPPSLEDSPISSHHPDFSavPQPMMGSLIVIMVgLPGRGKTYVARQIQRYFQWNGLQsri 248

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1508602860  509 ---QENLRRLAAKGDVqgvtqVLNILGKAESESVVAAAKA 545
Cdd:PTZ00322   249 fihQAYRRRLERRGGA-----VSSPTGAAEVEFRIAKAIA 283
Ank_4 pfam13637
Ankyrin repeats (many copies);
535-594 3.59e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 45.34  E-value: 3.59e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  535 ESESVVAAAKAGHEEVLQYLLAMGeADPDPPPLSGlpqgyNTPILAAIGRGNLDVIRLLV 594
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKG-ADINAVDGNG-----ETALHFAASNGNVEVLKLLL 54
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 382-409 3.98e-06

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 44.50  E-value: 3.98e-06
                            10        20
                    ....*....|....*....|....*...
gi 1508602860   382 DKDTPLIDAVENGHVEVVKLLLDHGANP 409
Cdd:smart00248    1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
Ank_4 pfam13637
Ankyrin repeats (many copies);
316-370 6.79e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 44.57  E-value: 6.79e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1508602860  316 GRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLL 370
Cdd:pfam13637    1 ELTALHAAAASGHLELLR-LLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 327-412 7.07e-06

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 50.64  E-value: 7.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  327 DDLEKAKVylkerpdDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLL--LD 404
Cdd:PLN03192   542 EELLKAKL-------DPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILyhFA 614


                   ....*...
gi 1508602860  405 HGANPRLG 412
Cdd:PLN03192   615 SISDPHAA 622
Ank_5 pfam13857
Ankyrin repeats (many copies);
369-423 1.06e-05

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 43.87  E-value: 1.06e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1508602860  369 LLSN-NAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGANPRLGNAKGEEPYELV 423
Cdd:pfam13857    1 LLEHgPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 320-434 1.25e-05

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 49.87  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  320 LSRACNNDDLEKAKVYLKERPDdLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKD-TP-----LIDAVEN 393
Cdd:PLN03192   626 LCTAAKRNDLTAMKELLKQGLN-VDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKANTDDDfSPtelreLLQKREL 704

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1508602860  394 GHVEVV--KLLLDHganPRLGNAKGEEPYELVPSDDENYKTIR 434
Cdd:PLN03192   705 GHSITIvdSVPADE---PDLGRDGGSRPGRLQGTSSDNQCRPR 744
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 342-416 1.27e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 49.51  E-value: 1.27e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1508602860  342 DLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGANPRLGNAKG 416
Cdd:PTZ00322   107 DPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELGANA 181
PHA03095 PHA03095
ankyrin-like protein; Provisional
 342-591 1.71e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 48.87  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  342 DLDLPDNAGNTPLQIAALEGFV-DIVKFLLSNNAEVDTRNIDKDTPL--IDAVENGHVEVVKLLLDHGANPRLGNAKGEE 418
Cdd:PHA03095    75 DVNAPERCGFTPLHLYLYNATTlDVIKLLIKAGADVNAKDKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMT 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  419 PYE-LVPSDDENYKTIRKLIAnakeqeypkrrRSNDKRDDDASSRGA---SANSPRESPGpmvgprspppYLSSRRRTGR 494
Cdd:PHA03095   155 PLAvLLKSRNANVELLRLLID-----------AGADVYAVDDRFRSLlhhHLQSFKPRAR----------IVRELIRAGC 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  495 SEVTRNDL----LWQANTQENLRR------LAAKGDVqgvtQVLNILGKAeseSVVAAAKAGHEEVLQYLLAMGeADPDP 564
Cdd:PHA03095   214 DPAATDMLgntpLHSMATGSSCKRslvlplLIAGISI----NARNRYGQT---PLHYAAVFNNPRACRRLIALG-ADINA 285

                          250       260
                   ....*....|....*....|....*..
gi 1508602860  565 PPLSGlpqgyNTPILAAIGRGNLDVIR 591
Cdd:PHA03095   286 VSSDG-----NTPLSLMVRNNNGRAVR 307
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 1211-1285 1.83e-05

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 44.76  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860 1211 GLAR-------GLREASKALDRRQAHMCVLNEACEEEAYKKLVvALCQEHKIPLIKVPDGKQLGEWAG------LCVLDr 1277
Cdd:COG1358      8 GLARragklvsGEEQVLKAIRKGKAKLVIIAEDASENTKKKLL-DLCEEYGVPVVEVGTKEELGKAIGkvgravVAITD- 85


                   ....*...
gi 1508602860 1278 EGNARKVV 1285
Cdd:COG1358     86 EGFAKKLL 93
PHA03095 PHA03095
ankyrin-like protein; Provisional
 324-439 2.18e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 48.48  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  324 CNNDDLEKAKVYLKERPDdLDLPDNAGNTPLQI---AALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVE-VV 399
Cdd:PHA03095    22 ASNVTVEEVRRLLAAGAD-VNFRGEYGKTPLHLylhYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLdVI 100

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1508602860  400 KLLLDHGANPRLGNAKGEEPYELVPSDDE-NYKTIRKLIAN 439
Cdd:PHA03095   101 KLLIKAGADVNAKDKVGRTPLHVYLSGFNiNPKVIRLLLRK 141
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 348-437 2.55e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 48.34  E-value: 2.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  348 NAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGANPRLGNAKGEEPYELVPSDD 427
Cdd:PHA02878   166 HKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYC 245

                           90
                   ....*....|
gi 1508602860  428 ENYKTIRKLI 437
Cdd:PHA02878   246 KDYDILKLLL 255
Ank_2 pfam12796
Ankyrin repeats (3 copies);
542-616 4.71e-05

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 43.18  E-value: 4.71e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1508602860  542 AAKAGHEEVLQYLLAMGeADPDPPPLSGLpqgynTPILAAIGRGNLDVIRLLVEQsrFDPTRRFNKKTYFQIALE 616
Cdd:pfam12796    4 AAKNGNLELVKLLLENG-ADANLQDKNGR-----TALHLAAKNGHLEIVKLLLEH--ADVNLKDNGRTALHYAAR 70
PHA03095 PHA03095
ankyrin-like protein; Provisional
 312-410 5.37e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 47.33  E-value: 5.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  312 RDKNGRT-FLSRACNNDDLEKAKVYLKeRPDDLDLPDNAGNTPLQIAaLEGF---VDIVKFLLSNNAEVDTRNIDKDTPL 387
Cdd:PHA03095    79 PERCGFTpLHLYLYNATTLDVIKLLIK-AGADVNAKDKVGRTPLHVY-LSGFninPKVIRLLLRKGADVNALDLYGMTPL 156

                           90       100
                   ....*....|....*....|....*
gi 1508602860  388 IDAVENGH--VEVVKLLLDHGANPR 410
Cdd:PHA03095   157 AVLLKSRNanVELLRLLIDAGADVY 181
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 318-453 6.11e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 46.91  E-value: 6.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  318 TFLSRACNNDDLEKAKVYLKERPDdLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVD--TRNIDKdTPLIDAVENGH 395
Cdd:PHA02875   137 SPLHLAVMMGDIKGIELLIDHKAC-LDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDyfGKNGCV-AALCYAIENNK 214

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1508602860  396 VEVVKLLLDHGANPRL-GNAKGEE--PYELVPSDDENYKT--IRKLIANAKEQEYPKRRRSND 453
Cdd:PHA02875   215 IDIVRLFIKRGADCNImFMIEGEEctILDMICNMCTNLESeaIDALIADIAIRIHKKTIRRDE 277
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 363-439 6.17e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 46.97  E-value: 6.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  363 VDIVKFLLSNNAEVDTRNIDKDTPLIDAVEN--GHVEVVKLLLDHGANPRLGNAKGEEPYEL-VPSDDENYKTIRKLIAN 439
Cdd:PHA03100    86 KEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLLHLyLESNKIDLKILKLLIDK 165
PHA02798 PHA02798
ankyrin-like protein; Provisional
 342-416 6.27e-05

ankyrin-like protein; Provisional


Pssm-ID: 222931 [Multi-domain]  Cd Length: 489  Bit Score: 47.14  E-value: 6.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  342 DLDLPDNAGNTPL-----QIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHV---EVVKLLLDHGANPRLGN 413
Cdd:PHA02798    63 NVNGLDNEYSTPLctilsNIKDYKHMLDIVKILIENGADINKKNSDGETPLYCLLSNGYInnlEILLFMIENGADTTLLD 142


                   ...
gi 1508602860  414 AKG 416
Cdd:PHA02798   143 KDG 145
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 350-380 6.66e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 41.12  E-value: 6.66e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1508602860  350 GNTPLQIAALE-GFVDIVKFLLSNNAEVDTRN 380
Cdd:pfam00023    2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARD 33
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 382-409 1.17e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 40.35  E-value: 1.17e-04
                           10        20
                   ....*....|....*....|....*....
gi 1508602860  382 DKDTPLIDAVE-NGHVEVVKLLLDHGANP 409
Cdd:pfam00023    1 DGNTPLHLAAGrRGNLEIVKLLLSKGADV 29
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 687-867 1.71e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  687 KSPRSATKDRKRSDiSPPNSDRRSTLAAYDDADSvavSSDQDRSVPQGKSDKHRSQSDPHTTAESEV--EPAQRRRRlmt 764
Cdd:PTZ00449   495 KLAPIEEEDSDKHD-EPPEGPEASGLPPKAPGDK---EGEEGEHEDSKESDEPKEGGKPGETKEGEVgkKPGPAKEH--- 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  765 gkdyrKQGRKHSATSGPRGDESGHEEKRESQAPGLKRARD-SFSQSPESSKEPESrVKVKKRRTIPESPEESHVGLPPRK 843
Cdd:PTZ00449   568 -----KPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSaQRPTRPKSPKLPEL-LDIPKSPKRPESPKSPKRPPPPQR 641

                          170       180
                   ....*....|....*....|....
gi 1508602860  844 PSKPSEPQDAEMKDVKAPPPSNVP 867
Cdd:PTZ00449   642 PSSPERPEGPKIIKSPKPPKSPKP 665
Ank_5 pfam13857
Ankyrin repeats (many copies);
335-387 1.86e-04

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.41  E-value: 1.86e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1508602860  335 YLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPL 387
Cdd:pfam13857    1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 310-407 2.98e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 44.87  E-value: 2.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  310 KFRDKN-GRTFLSRACNNDDLEKAKvYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLI 388
Cdd:PHA02878   161 NMKDRHkGNTALHYATENKDQRLTE-LLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLH 239

                           90       100
                   ....*....|....*....|..
gi 1508602860  389 DAVenGHV---EVVKLLLDHGA 407
Cdd:PHA02878   240 ISV--GYCkdyDILKLLLEHGV 259
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 350-378 4.92e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 38.78  E-value: 4.92e-04
                           10        20
                   ....*....|....*....|....*....
gi 1508602860  350 GNTPLQIAALEGFVDIVKFLLSNNAEVDT 378
Cdd:pfam13606    2 GNTPLHLAARNGRLEIVKLLLENGADINA 30
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 350-377 5.06e-04

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 38.72  E-value: 5.06e-04
                            10        20
                    ....*....|....*....|....*...
gi 1508602860   350 GNTPLQIAALEGFVDIVKFLLSNNAEVD 377
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGADIN 29
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 328-408 8.36e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 43.41  E-value: 8.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  328 DLEKAKVYLKERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAEVDTRNIDKDTPLIDAVENGHVEVVKLLLDHGA 407
Cdd:PHA02874    13 DIEAIEKIIKNKGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGV 92


                   .
gi 1508602860  408 N 408
Cdd:PHA02874    93 D 93
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 363-441 8.50e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 43.50  E-value: 8.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  363 VDIVKFLLSNNAEVDTRNIDKDTPL-----IDAVENGHVEVVKLLLDHGANPRLGNAKGEEP-YELVPSDDENYKTIRKL 436
Cdd:PHA03100    48 IDVVKILLDNGADINSSTKNNSTPLhylsnIKYNLTDVKEIVKLLLEYGANVNAPDNNGITPlLYAISKKSNSYSIVEYL 127


                   ....*
gi 1508602860  437 IANAK 441
Cdd:PHA03100   128 LDNGA 132
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 312-375 1.22e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 43.35  E-value: 1.22e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1508602860  312 RDKNGRTFLSRACNNDDLEKAKVYLkERPDDLDLPDNAGNTPLQIAALEGFVDIVKFLLSNNAE 375
Cdd:PTZ00322   111 RDYDGRTPLHIACANGHVQVVRVLL-EFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQC 173
Ank_2 pfam12796
Ankyrin repeats (3 copies);
387-419 1.78e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.94  E-value: 1.78e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1508602860  387 LIDAVENGHVEVVKLLLDHGANPRLGNAKGEEP 419
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTA 33
Ank_2 pfam12796
Ankyrin repeats (3 copies);
541-595 2.83e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.17  E-value: 2.83e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1508602860  541 AAAKAGHEEVLQYLLAMGEADPDPpplsglpqGYNTPILAAIGRGNLDVIRLLVE 595
Cdd:pfam12796   36 LAAKNGHLEIVKLLLEHADVNLKD--------NGRTALHYAARSGHLEIVKLLLE 82
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 657-919 3.30e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  657 DHVGPTSSSPVSGALRNST----SPTLTHRSLPAKSPRSATKDRKRSDISPPNSDRRSTLAAYDDADSVAVSSDQDRSVP 732
Cdd:PHA03307   165 DAASSRQAALPLSSPEETArapsSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSES 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  733 QGKSDKHRSQSDPHTTAESEVEPAQRRRRLMTGKDYRKQ-GRKHSATSGPRGD-ESGHEEKRESQAPglKRARDSFSQSP 810
Cdd:PHA03307   245 SGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGpASSSSSPRERSPSpSPSSPGSGPAPSS--PRASSSSSSSR 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  811 ESSKEPESRVKVKKRRTIPESPEESHvglPPRKPSKPSEPQDAEMKDVKAPPPSNVPTIVEQRLQQPSEEARPDQD---- 886
Cdd:PHA03307   323 ESSSSSTSSSSESSRGAAVSPGPSPS---RSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAgrar 399

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1508602860  887 ------PTPISRALPSVTTTSETHTTGPVDGKP--------IGVPDP 919
Cdd:PHA03307   400 rrdatgRFPAGRPRPSPLDAGAASGAFYARYPLltpsgepwPGSPPP 446
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 324-447 4.30e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 41.40  E-value: 4.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  324 CNNDDLEKAKVY--------LKERPDDLDLPDNAGNTPLQIAAleGFV---DIVKFLLSNNAEVDTRN-IDKDTPLIDAV 391
Cdd:PHA02878   200 TNNSPLHHAVKHynkpivhiLLENGASTDARDKCGNTPLHISV--GYCkdyDILKLLLEHGVDVNAKSyILGLTALHSSI 277

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1508602860  392 ENGhvEVVKLLLDHGANPRLGNAKGEEPYELVPSDDENYKTIRKLIANAKEQEYPK 447
Cdd:PHA02878   278 KSE--RKLKLLLEYGADINSLNSYKLTPLSSAVKQYLCINIGRILISNICLLKRIK 331
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 315-458 6.19e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 40.82  E-value: 6.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  315 NGRTFLSRACNNDDLEKAKVYLKERPD----DLDLPDNAGNTPLQIAALegfvdivkfLLSNNAEVDTRNIDKDTPLIDA 390
Cdd:PHA02876   210 DDLSVLECAVDSKNIDTIKAIIDNRSNinknDLSLLKAIRNEDLETSLL---------LYDAGFSVNSIDDCKNTPLHHA 280

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1508602860  391 VENGHV-EVVKLLLDHGANPRLGNAKGEEPYELVPSDDENYKTIRKLIA-----NAKEQEY--PKRRRSNDKRDDD 458
Cdd:PHA02876   281 SQAPSLsRLVPKLLERGADVNAKNIKGETPLYLMAKNGYDTENIRTLIMlgadvNAADRLYitPLHQASTLDRNKD 356
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 320-419 6.38e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 40.63  E-value: 6.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  320 LSRACNNDDLEKAKVYLKERPDDL-DLPDNAGNTPLQIAALEgfVDIVKFLLSNNAEVDTRNIDKD-TPLIDAVENGHVE 397
Cdd:PHA02878   105 IKDAFNNRNVEIFKIILTNRYKNIqTIDLVYIDKKSKDDIIE--AEITKLLLSYGADINMKDRHKGnTALHYATENKDQR 182

                           90       100
                   ....*....|....*....|..
gi 1508602860  398 VVKLLLDHGANPRLGNAKGEEP 419
Cdd:PHA02878   183 LTELLLSYGANVNIPDKTNNSP 204
PHA03247 PHA03247
large tegument protein UL36; Provisional
 659-896 6.58e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 6.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  659 VGPTSSSPVSGALRNSTSPTLTHRSLPAKSPRSATKdrkRSDISPPNSDRRSTLAAYDDADSVAVSSDQDRSVPQGKSDk 738
Cdd:PHA03247  2749 ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP- 2824

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  739 hrSQSDPHTTAESEVEPAQRRRRLMT----------GKDYRKQGRKHSATSGPRGdeSGHEEKRESQAPGLKRARDSFSQ 808
Cdd:PHA03247  2825 --AGPLPPPTSAQPTAPPPPPGPPPPslplggsvapGGDVRRRPPSRSPAAKPAA--PARPPVRRLARPAVSRSTESFAL 2900

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1508602860  809 SPESSKEPESRVKVKKRRTIPESPEESHVGLPPRKPSKPSEPQDAEMKDVKAPPPSNVP------TIVEQRLQQPSEEAR 882
Cdd:PHA03247  2901 PPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVpqpwlgALVPGRVAVPRFRVP 2980

                          250
                   ....*....|....
gi 1508602860  883 PDQDPTPISRALPS 896
Cdd:PHA03247  2981 QPAPSREAPASSTP 2994
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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