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Conserved domains on  [gi|1489553191|gb|RKV62021|]
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DNA polymerase III subunit gamma/tau [Helicobacter pylori]

Protein Classification

ATP-binding protein( domain architecture ID 11483305)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to magnesium-chelatase subunit ChlI and RuvB-like helicase 1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
1-590 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 898.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:PRK08451    1 MQALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK08451   81 LENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK08451  161 PATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQDEARLKERYAILENYETEGVLEEMMLFLKAKLLSPDS-YSILLIERFFKIIMSSLSLLKEGAN 319
Cdd:PRK08451  241 LLDPSKLEDFFQAILNQDKEKLFELLKELEDYEAEMVLDEMMLFLKEKFLSKDSeFSILLYERFFRILSSAKSLLKEGAD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 320 ASFVLLLLKMKFKEALKLKALDDAILELEQTPFNqnPSISYNAPKQEPKSTEKREqaeriegtekreklekrenaetpqt 399
Cdd:PRK08451  321 DGFVLLLMLFKMKEALKLKEIDDAIEELEQEKTT--AIIPLNTPAPIIPNTEKEE------------------------- 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 400 pmlsAKDRIFHNLFKQVQTLVYERNYELGAVFEKNIRFIDFDSQTktLTWESLATDKDKELLRERFKIVKSIVDGVFGKG 479
Cdd:PRK08451  374 ----AKDRIFKNLFEQLLDKIYDRNYELGECFEKNIRFIDFDSNT--LTWESNAQGEDKELLRKGFKIIKEIVDEVFGKG 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 480 ENIKIalknHSENKSAREETKEIKDFKISSLREKILPQPTTETTAEMKEKEtkeavkkeikekeikenDTKEIQETQPKE 559
Cdd:PRK08451  448 AKIKI----QKALKSAENPLQSLKEFKPSNEKKKIDTESTAEMLEEEAKKD-----------------DEEVQETQLKEA 506
                         570       580       590
                  ....*....|....*....|....*....|.
gi 1489553191 560 SPtaLQEFMANHSELIEEIKSEFEIKSVELL 590
Cdd:PRK08451  507 TE--LQEFMINNEDLIEEAKELFGIKSIELL 535
 
Name Accession Description Interval E-value
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
1-590 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 898.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:PRK08451    1 MQALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK08451   81 LENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK08451  161 PATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQDEARLKERYAILENYETEGVLEEMMLFLKAKLLSPDS-YSILLIERFFKIIMSSLSLLKEGAN 319
Cdd:PRK08451  241 LLDPSKLEDFFQAILNQDKEKLFELLKELEDYEAEMVLDEMMLFLKEKFLSKDSeFSILLYERFFRILSSAKSLLKEGAD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 320 ASFVLLLLKMKFKEALKLKALDDAILELEQTPFNqnPSISYNAPKQEPKSTEKREqaeriegtekreklekrenaetpqt 399
Cdd:PRK08451  321 DGFVLLLMLFKMKEALKLKEIDDAIEELEQEKTT--AIIPLNTPAPIIPNTEKEE------------------------- 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 400 pmlsAKDRIFHNLFKQVQTLVYERNYELGAVFEKNIRFIDFDSQTktLTWESLATDKDKELLRERFKIVKSIVDGVFGKG 479
Cdd:PRK08451  374 ----AKDRIFKNLFEQLLDKIYDRNYELGECFEKNIRFIDFDSNT--LTWESNAQGEDKELLRKGFKIIKEIVDEVFGKG 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 480 ENIKIalknHSENKSAREETKEIKDFKISSLREKILPQPTTETTAEMKEKEtkeavkkeikekeikenDTKEIQETQPKE 559
Cdd:PRK08451  448 AKIKI----QKALKSAENPLQSLKEFKPSNEKKKIDTESTAEMLEEEAKKD-----------------DEEVQETQLKEA 506
                         570       580       590
                  ....*....|....*....|....*....|.
gi 1489553191 560 SPtaLQEFMANHSELIEEIKSEFEIKSVELL 590
Cdd:PRK08451  507 TE--LQEFMINNEDLIEEAKELFGIKSIELL 535
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
1-350 1.99e-141

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 413.89  E-value: 1.99e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQD--EARLKERYAILENYETEGVLEEMMLFLKAKLLSPDSYSILL-IERFFKIIMSSLSLLKeg 317
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDtaEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLaVLESEQEFLKELALKL-- 318
                         330       340       350
                  ....*....|....*....|....*....|...
gi 1489553191 318 aNASFVLLLLKMKFKEALKLKALDDAILELEQT 350
Cdd:TIGR02397 319 -SLEFLLRLLDILLEALKDLRFSNDPRIWLEMT 350
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
10-329 5.26e-121

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 361.05  E-value: 5.26e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  10 PKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDII 89
Cdd:COG2812     6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVI 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  90 EMDG-ASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRT 168
Cdd:COG2812    86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 169 QHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCD-----------NAITESKVAE 237
Cdd:COG2812   166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGLldrrellldllEALLAGDVAA 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 238 MLGAIDRSV-----LEDFFQSLIN--QDEARLKERyAILENYETEGVLEEMMLFlkAKLLSPDSysillIERFFKIIMSS 310
Cdd:COG2812   246 LLALAEELAkrgrdLKRFLDDLLSllRDLLLLKLG-PDAELLVNEDERERLQEL--ARRLSPER-----LLRAIQILLEA 317
                         330       340
                  ....*....|....*....|.
gi 1489553191 311 LSLLKEGANASFVL--LLLKM 329
Cdd:COG2812   318 RRELERNVNPRLALemLLLRL 338
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
18-177 5.06e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 159.30  E-value: 5.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  18 GQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDI--IEMDGAS 95
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLviIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  96 NRgIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKK 175
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  ..
gi 1489553191 176 IP 177
Cdd:pfam13177 160 LS 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
176-240 8.74e-21

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 86.02  E-value: 8.74e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489553191 176 IPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
39-152 5.54e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 43.52  E-value: 5.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   39 YLFSGLRGSGKTSSSRIFARALMCEEGP-KAVPCDTCTQCQSALNNHHidIIEMDGASNRGIDDVRNLIEQTRYKpsfgR 117
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLI--IVGGKKASGSGELRLRLALALARKL----K 78
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1489553191  118 YKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLL 152
Cdd:smart00382  79 PDVLILDEITSLLDAEQEALLLLLEELRLLLLLKS 113
 
Name Accession Description Interval E-value
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
1-590 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 898.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:PRK08451    1 MQALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK08451   81 LENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK08451  161 PATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQDEARLKERYAILENYETEGVLEEMMLFLKAKLLSPDS-YSILLIERFFKIIMSSLSLLKEGAN 319
Cdd:PRK08451  241 LLDPSKLEDFFQAILNQDKEKLFELLKELEDYEAEMVLDEMMLFLKEKFLSKDSeFSILLYERFFRILSSAKSLLKEGAD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 320 ASFVLLLLKMKFKEALKLKALDDAILELEQTPFNqnPSISYNAPKQEPKSTEKREqaeriegtekreklekrenaetpqt 399
Cdd:PRK08451  321 DGFVLLLMLFKMKEALKLKEIDDAIEELEQEKTT--AIIPLNTPAPIIPNTEKEE------------------------- 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 400 pmlsAKDRIFHNLFKQVQTLVYERNYELGAVFEKNIRFIDFDSQTktLTWESLATDKDKELLRERFKIVKSIVDGVFGKG 479
Cdd:PRK08451  374 ----AKDRIFKNLFEQLLDKIYDRNYELGECFEKNIRFIDFDSNT--LTWESNAQGEDKELLRKGFKIIKEIVDEVFGKG 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 480 ENIKIalknHSENKSAREETKEIKDFKISSLREKILPQPTTETTAEMKEKEtkeavkkeikekeikenDTKEIQETQPKE 559
Cdd:PRK08451  448 AKIKI----QKALKSAENPLQSLKEFKPSNEKKKIDTESTAEMLEEEAKKD-----------------DEEVQETQLKEA 506
                         570       580       590
                  ....*....|....*....|....*....|.
gi 1489553191 560 SPtaLQEFMANHSELIEEIKSEFEIKSVELL 590
Cdd:PRK08451  507 TE--LQEFMINNEDLIEEAKELFGIKSIELL 535
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
1-350 1.99e-141

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 413.89  E-value: 1.99e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQD--EARLKERYAILENYETEGVLEEMMLFLKAKLLSPDSYSILL-IERFFKIIMSSLSLLKeg 317
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDtaEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLaVLESEQEFLKELALKL-- 318
                         330       340       350
                  ....*....|....*....|....*....|...
gi 1489553191 318 aNASFVLLLLKMKFKEALKLKALDDAILELEQT 350
Cdd:TIGR02397 319 -SLEFLLRLLDILLEALKDLRFSNDPRIWLEMT 350
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
10-329 5.26e-121

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 361.05  E-value: 5.26e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  10 PKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDII 89
Cdd:COG2812     6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVI 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  90 EMDG-ASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRT 168
Cdd:COG2812    86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 169 QHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCD-----------NAITESKVAE 237
Cdd:COG2812   166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGLldrrellldllEALLAGDVAA 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 238 MLGAIDRSV-----LEDFFQSLIN--QDEARLKERyAILENYETEGVLEEMMLFlkAKLLSPDSysillIERFFKIIMSS 310
Cdd:COG2812   246 LLALAEELAkrgrdLKRFLDDLLSllRDLLLLKLG-PDAELLVNEDERERLQEL--ARRLSPER-----LLRAIQILLEA 317
                         330       340
                  ....*....|....*....|.
gi 1489553191 311 LSLLKEGANASFVL--LLLKM 329
Cdd:COG2812   318 RRELERNVNPRLALemLLLRL 338
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
3-262 7.65e-111

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 343.26  E-value: 7.65e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALN 82
Cdd:PRK14965    5 VLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITE 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  83 NHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPA 162
Cdd:PRK14965   85 GRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 163 TILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGAI 242
Cdd:PRK14965  165 TILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAELLGVV 244
                         250       260
                  ....*....|....*....|
gi 1489553191 243 DRSVLEDFFQSLINQDEARL 262
Cdd:PRK14965  245 DRRLLLDISAAVFGRDTRAL 264
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
2-281 1.47e-110

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 344.54  E-value: 1.47e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK07994    4 QVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCREIE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK07994   84 QGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK07994  164 VTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGT 243
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1489553191 242 IDRSVLEDFFQSLINQDEARLKE--RYAILENYETEGVLEEM 281
Cdd:PRK07994  244 LDDDQALSLLEALVEGDGERVMAliNQLAERGPDWEGLLVEL 285
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-390 3.09e-110

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 341.08  E-value: 3.09e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLAL--KYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQ 78
Cdd:PRK05563    1 MMYQALyrKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  79 SALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDAL 158
Cdd:PRK05563   81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEM 238
Cdd:PRK05563  161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 239 LGAIDRSVLEDFFQSLINQDEARLkerYAILENYETEG-----VLEEMMLFLKAKLL---SPDSYSILL----------- 299
Cdd:PRK05563  241 TGSVSQEALDDLVDAIVEGDVAKA---LKILEELLDEGkdpnrFIEDLIYYLRDLLLvktSPELEILDEstendelfkel 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 300 -----IERFFKII---MSSLSLLKEGANASFVL--LLLKM-----------KFKEALK--LKALDDAILELEQTPFNQNP 356
Cdd:PRK05563  318 sekldIERLYRMIdilNDAQQQIKWTNQPRIYLevALVKLceqaaaspeydTELEVLLqrVEQLEQELKQLKAQPVGVAP 397
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 1489553191 357 SISYNAPKQEPKSTEK----REQAERIEGTEKREKLEK 390
Cdd:PRK05563  398 EQKEKKKEKKKNKKKKykvpRGKIYKVLKEATRQDLEL 435
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
2-262 4.07e-107

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 332.10  E-value: 4.07e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14969    4 QVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEID 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14969   84 SGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14969  164 VTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAMLGA 243
                         250       260
                  ....*....|....*....|.
gi 1489553191 242 IDRSVLEDFFQSLINQDEARL 262
Cdd:PRK14969  244 IDQDYLFALLEALLAQDGAAL 264
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
2-267 7.28e-104

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 325.70  E-value: 7.28e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCE-----EGPKAVPCDTCTQ 76
Cdd:PRK09111   12 RVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEgpdgdGGPTIDLCGVGEH 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  77 CQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTD 156
Cdd:PRK09111   92 CQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 157 ALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVA 236
Cdd:PRK09111  172 IRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAVR 251
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1489553191 237 EMLGAIDRSVLEDFFQSLINQDEAR----LKERYA 267
Cdd:PRK09111  252 DMLGLADRARVIDLFEALMRGDVAAalaeFRAQYD 286
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
2-281 3.01e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 322.43  E-value: 3.01e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEeGP------KAVPCDTCT 75
Cdd:PRK14951    4 LVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQ-GPdgqggiTATPCGVCQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  76 QCQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATT 155
Cdd:PRK14951   83 ACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 156 DALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKV 235
Cdd:PRK14951  163 DPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEAAV 242
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1489553191 236 AEMLGAIDRSVLEDFFQSLINQDEARLKERYAIL--ENYETEGVLEEM 281
Cdd:PRK14951  243 RQMLGSVDRSHVFRLIDALAQGDGRTVVETADELrlNGLSAASTLEEM 290
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2-262 7.94e-100

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 318.36  E-value: 7.94e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMC-----EEGPKAVPCDTCTQ 76
Cdd:PRK12323    4 QVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCtgadgEGGITAQPCGQCRA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  77 CQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTD 156
Cdd:PRK12323   84 CTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 157 ALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVA 236
Cdd:PRK12323  164 PQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEEAVR 243
                         250       260
                  ....*....|....*....|....*.
gi 1489553191 237 EMLGAIDRSVLEDFFQSLINQDEARL 262
Cdd:PRK12323  244 GMLGAIDQSYLVRLLDALAAEDGAAL 269
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2-247 2.11e-97

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 315.25  E-value: 2.11e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK07003    4 QVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREID 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK07003   84 EGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK07003  164 VTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGMLGA 243

                  ....*.
gi 1489553191 242 IDRSVL 247
Cdd:PRK07003  244 LDQTYM 249
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
2-407 7.43e-96

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 308.18  E-value: 7.43e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK08691    4 QVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQID 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK08691   84 AGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK08691  164 VTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQMIGA 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 242 IDRSVLEDFFQSLINQDEA-------RLKERYAILENY--ETEGVLEEMMLF--LKAKLLSPDSYSILL----------- 299
Cdd:PRK08691  244 VDKQYLYELLTGIINQDGAallakaqEMAACAVGFDNAlgELAILLQQLALIqaVPSALAHDDPDSDILhrlaqtisgeq 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 300 IERFFKIIM---SSLSLLKEgANASFVLLLLKMkfkealklkalddaileLEQTPFNQnPSISYNAPKQEPKSTEKREQA 376
Cdd:PRK08691  324 IQLYYQIAVhgkRDLSLAPD-EYAGFMMTLLRM-----------------LAFAPLAA-ASCDANAVIENTELQSPSAQT 384
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1489553191 377 ERIEGTEKreKLEKRENAETPQTPMLSAKDR 407
Cdd:PRK08691  385 AEKETAAK--KPQPRPEAETAQTPVQTASAA 413
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
2-283 4.74e-89

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 286.28  E-value: 4.74e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK06647    4 RGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSID 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK06647   84 NDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK06647  164 ATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSKMGL 243
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1489553191 242 IDRSVLEDFFQSLINQDearLKERYAILENYETEGVLEEMML 283
Cdd:PRK06647  244 TGDEFLEKLASSILNED---AKELLCVLDSVFLSGVSVEQFL 282
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
5-314 5.94e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 283.64  E-value: 5.94e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   5 ALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNH 84
Cdd:PRK14953    7 ARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGS 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  85 HIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATI 164
Cdd:PRK14953   87 FPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 165 LSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGAIDR 244
Cdd:PRK14953  167 LSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEFLGIVSQ 246
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1489553191 245 SVLEDFFQSLINQDearLKERYAILENYETEG---------VLEEMMLFLKAKLLSpDSYSILLIERFFKIIMSSLSLL 314
Cdd:PRK14953  247 ESVRKFLNLLLESD---VDEAIKFLRTLEEKGynlnkfwkqLEEEIRNILLNKSLK-NPEEVFQVEDFYRKLEKPLEAL 321
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
4-271 1.31e-88

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 286.47  E-value: 1.31e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   4 LALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMC--EEGPKAVPCDTCTQCQ--- 78
Cdd:PRK14948    6 LHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCELCRaia 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  79 --SALnnhhiDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTD 156
Cdd:PRK14948   86 agNAL-----DVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 157 ALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQaINYCDNAITESKVA 236
Cdd:PRK14948  161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1489553191 237 EMLGAIDRSVLEDFFQSLINQD-EA----------RLKERYAILEN 271
Cdd:PRK14948  240 DLLGAVPEQDLLNLLKALASNDpESlldscrqlldRGREPLAILQG 285
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
4-258 5.38e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 285.42  E-value: 5.38e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   4 LALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNN 83
Cdd:PRK14959    6 LTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  84 HHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPAT 163
Cdd:PRK14959   86 MHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 164 ILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGAID 243
Cdd:PRK14959  166 IVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGVLGLAG 245
                         250
                  ....*....|....*
gi 1489553191 244 RSVLEDFFQSLINQD 258
Cdd:PRK14959  246 QELFLRLMEALAAQD 260
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
4-258 9.28e-88

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 280.52  E-value: 9.28e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   4 LALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNN 83
Cdd:PRK14964    3 LALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  84 HHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPAT 163
Cdd:PRK14964   83 NHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 164 ILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGAID 243
Cdd:PRK14964  163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVD 242
                         250
                  ....*....|....*
gi 1489553191 244 RSVLEDFFQSLINQD 258
Cdd:PRK14964  243 KHILEDLVEAILLGD 257
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-525 1.31e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 286.71  E-value: 1.31e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLAL--KYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEgpKAVPCDTCTQCQ 78
Cdd:PRK07133    3 MKYKALyrKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSH--KTDLLEPCQECI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  79 SALNNHhIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDAL 158
Cdd:PRK07133   81 ENVNNS-LDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVH 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEM 238
Cdd:PRK07133  160 KIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEEL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 239 LGAIDRSVLEDFFQSLINQDearLKERYAILENYETEG------------VLEEMMLFLKAK---LLSPDSYSILL---- 299
Cdd:PRK07133  240 FGLVSNENLINLLNLLYSKD---IKEVLNILNQIKEQGidpelllislinLVKEFIIFNKTKdnsLLEYYSEEDLEklki 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 300 -IERFFKIIMSSLSLLKEGANASFVLLLLKMKFkeaLKLKALDDAILELEQTpfNQNPSISYNAPKQEPKSTEKREQAER 378
Cdd:PRK07133  317 dDDFAYKFIEILFDLLKDLKISDNPNDTLEILI---IKLLALSELEEEDENE--IKFKKIEENSIDNLDIKEKKIENEND 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 379 IEGTEKREKLEKRENAETpqtpmLSAKDRIFHNLFKQ-------VQTLVYERNYELGAVFEKNIRFIDFDSQTKTLTWES 451
Cdd:PRK07133  392 IEGKSDTKNLEEGFETKD-----NKNKNSSFINKTENiltnsplKDELLEKTTEIINIENPQEFEFGQIGNDIISTEIAQ 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 452 LATDKDK----ELLRERFKIVKSIVDGVFGKGENIKIAL------KNHSENKSAREETKEIKDFKISSLREKILPQPTTE 521
Cdd:PRK07133  467 LDENQNLidtgEFDLENNFSNSFNPENGNKIDENINETFdtstisANLSENKTNFAQSFNNKDTNLINSEIPIDLIKDTI 546

                  ....
gi 1489553191 522 TTAE 525
Cdd:PRK07133  547 TINN 550
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
2-264 1.59e-87

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 286.17  E-value: 1.59e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14960    3 QVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVN 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14960   83 EGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLP 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14960  163 ITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLGL 242
                         250       260
                  ....*....|....*....|...
gi 1489553191 242 IDRSVLEDFFQSLINQDEARLKE 264
Cdd:PRK14960  243 IDRTIIYDLILAVHQNQREKVSQ 265
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
2-258 6.13e-85

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 275.92  E-value: 6.13e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEE-GPKAVPCDTCTQCQSA 80
Cdd:PRK14950    4 QVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTnDPKGRPCGTCEMCRAI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK14950   84 AEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKV 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK14950  164 PATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQSLLG 243
                         250
                  ....*....|....*...
gi 1489553191 241 AIDRSVLEDFFQSLINQD 258
Cdd:PRK14950  244 ISGDEEVKALAEALLAKD 261
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
2-291 6.79e-84

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 269.34  E-value: 6.79e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEE-GPKAVPCDTCTQCQSA 80
Cdd:PRK06305    5 QVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNpTEDQEPCNQCASCKEI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK06305   85 SSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK06305  165 PGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKALG 244
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRsvledffQSLINQDEARLKERYA----ILENYETEGV-----LEEMMLFLKAKLLS 291
Cdd:PRK06305  245 LLSQ-------DSLYTLDEAITTQNYAqalePVTDAMNSGVapahfLHDLTLFFRNILLK 297
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
1-388 1.04e-82

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 267.02  E-value: 1.04e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:PRK14962    1 MEALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK14962   81 DEGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK14962  161 PPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 241 AIDRSVLEDFFQSLINQDEAR----LKERYAILENYETegVLEEMMLFLKAKLLSPDSYSILLIERFFkiimssLSLLKE 316
Cdd:PRK14962  241 LIPIEVVRDYINAIFNGDVKRvftvLDDVYYSGKDYEV--LIQQAIEDLVEDLERERANDIIQVSRQL------LNILRE 312
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1489553191 317 GANASFVLLLLKMKFKEALKLKALDDaILELEQTPFNQNPSISYNAPKQEpKSTEKREQAERIEGTEKREKL 388
Cdd:PRK14962  313 IKFAEEKRLVCKLGSASIATRFSSPN-VQENDVEEKNDNSNVQQKEKKKE-ESKAKEEKQEDIEFEKRFKEL 382
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
2-243 1.52e-81

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 275.07  E-value: 1.52e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14949    4 QVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVEIA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14949   84 QGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14949  164 VTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTMLGS 243

                  ..
gi 1489553191 242 ID 243
Cdd:PRK14949  244 ID 245
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
2-262 3.16e-80

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 263.66  E-value: 3.16e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQS-A 80
Cdd:PRK14952    1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVAlA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LN-NHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALK 159
Cdd:PRK14952   81 PNgPGSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 160 LPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAI-NYCDNAITESKVAEM 238
Cdd:PRK14952  161 VLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLaGAADTHVTYQRALGL 240
                         250       260
                  ....*....|....*....|....
gi 1489553191 239 LGAIDRSVLEDFFQSLINQDEARL 262
Cdd:PRK14952  241 LGATDVALIDDAVDALAADDAAAL 264
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
3-262 3.04e-78

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 263.77  E-value: 3.04e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLAL--KYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQS- 79
Cdd:PRK07764    2 ALALyrRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVAl 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  80 ALNNH-HIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDAL 158
Cdd:PRK07764   82 APGGPgSLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPD 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYC-DNAIT-ESKVA 236
Cdd:PRK07764  162 KVIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAGAgPEGVTyERAVA 241
                         250       260
                  ....*....|....*....|....*.
gi 1489553191 237 eMLGAIDRSVLEDFFQSLINQDEARL 262
Cdd:PRK07764  242 -LLGVTDSALIDEAVDALAAGDGAAL 266
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
3-259 4.13e-78

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 258.94  E-value: 4.13e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEE-GPKAVPCDTCTQCQSAL 81
Cdd:PRK14971    6 VSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNlTADGEACNECESCVAFN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14971   86 EQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKIL 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14971  166 PTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIENLNI 245
                         250       260
                  ....*....|....*....|....*..
gi 1489553191 242 IDRSV---LEDFF------QSLINQDE 259
Cdd:PRK14971  246 LDYDYyfrLTDALlagkvsDSLLLFDE 272
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-312 1.54e-77

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 254.40  E-value: 1.54e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCE----EGPKAVPCDTCTQCQ 78
Cdd:PRK06645   10 PFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSalitENTTIKTCEQCTNCI 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  79 SALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDAL 158
Cdd:PRK06645   90 SFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQ 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYC---DNAITESKV 235
Cdd:PRK06645  170 KIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSaksDNIISPQVI 249
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 236 AEMLGAIDRSVLEDFFQSLINQDEAR----LKERYAILENYET--EGVLEEMMLFLKAKLLspDSYSILLIERFFKIIMS 309
Cdd:PRK06645  250 NQMLGLVDSSVIIEFVEYIIHRETEKainlINKLYGSSVNLEIfiESVSDFIAYLNKVKML--PNYSLPIYESFNDRTKS 327

                  ...
gi 1489553191 310 SLS 312
Cdd:PRK06645  328 ILD 330
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
2-302 3.52e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 250.19  E-value: 3.52e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCE---EGPKAV-----PCDT 73
Cdd:PRK14955    4 QVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQrmiDDADYLqevtePCGE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  74 CTQCQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLA 153
Cdd:PRK14955   84 CESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 154 TTDALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYC-----DN 228
Cdd:PRK14955  164 TTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSvesegEG 243
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1489553191 229 AITESKVAEMLGAIDRSVLEDFFQSLINQDEARLKE--RYAILENYETEGVLEEMMLFLKAKLLSPDSYSILLIER 302
Cdd:PRK14955  244 SIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDvaQFVIRNGYDEQDFLEKLIEHLRNFLVVHNLRSTRLVER 319
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
2-285 9.22e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 247.80  E-value: 9.22e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14961    4 QILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14961   84 KGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14961  164 KTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDMLGL 243
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1489553191 242 IDRSVLEDFFQSLINQDEARLKERYAILEN--YETEGVLEEMMLFL 285
Cdd:PRK14961  244 LNEKQSFLLTDALLKKDSKKTMLLLNKISSigIEWENILIEMLRFL 289
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
2-258 1.58e-75

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 250.38  E-value: 1.58e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14957    4 QALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAIN 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14957   84 NNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14957  164 VTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQMLGI 243
                         250
                  ....*....|....*..
gi 1489553191 242 IDRSVLEDFFQSLINQD 258
Cdd:PRK14957  244 IDSEEVYSIINAIIDND 260
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
2-391 4.65e-74

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 248.32  E-value: 4.65e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCE---EGPKAV-----PCDT 73
Cdd:PRK14954    4 QVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQrmiDDPVYLqevtePCGE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  74 CTQCQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLA 153
Cdd:PRK14954   84 CESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 154 TTDALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAI-----NYCDN 228
Cdd:PRK14954  164 TTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIafsvgSEAEK 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 229 AITESKVAEMLGAIDRSVLEDFFQSLINQDEARLKE--RYAILENYETEGVLEEMMLFLKAKLLSPDSYSILLIERFFKI 306
Cdd:PRK14954  244 VIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEvaRFVIDNGYDEQDFLEKLIEHFRNFLVLYNLRSTRLIERPESV 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 307 I----MSSLSLLKEGANASFVLLL-----LKMKFKEALKLKALDDAILELEQTPFNQNPSISYNAPKQEPKSTEKREQAE 377
Cdd:PRK14954  324 KeryqQSAGGLTPAAVMQMTDFLMktqgeLKFQFEYQFRFELALLRLIELVRNDGGVAPSPAGSPDVKKKAPEPDLPQPD 403
                         410
                  ....*....|....
gi 1489553191 378 RIEGTEKREKLEKR 391
Cdd:PRK14954  404 RHPGPAKPEAPGAR 417
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
1-240 1.40e-72

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 241.28  E-value: 1.40e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEeGPKAVPCDTCTQCQSA 80
Cdd:PRK14963    1 MSALYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCS-GEDPKPCGECESCLAV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK14963   80 RRGAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKM 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINyCDNAITESKVAEMLG 240
Cdd:PRK14963  160 PPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLA-LGTPVTRKQVEEALG 238
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-277 8.29e-72

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 241.67  E-value: 8.29e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   1 MQVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSA 80
Cdd:PRK05896    3 EITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 LNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKL 160
Cdd:PRK05896   83 NTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKI 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 161 PATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:PRK05896  163 PLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKTFG 242
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1489553191 241 AIDRSVLEDFFQSLINQDearLKERYAILENYETEGV 277
Cdd:PRK05896  243 LVDNNKKINLIELIQKND---IEELRNLINELESKGI 276
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
2-262 2.32e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 238.09  E-value: 2.32e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14958    4 QVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREID 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14958   84 EGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14958  164 VTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTMLGT 243
                         250       260
                  ....*....|....*....|.
gi 1489553191 242 IDRSVLEDFFQSLINQDEARL 262
Cdd:PRK14958  244 IEPLLLFDILEALAAKAGDRL 264
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-277 7.07e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 236.00  E-value: 7.07e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   2 QVLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSAL 81
Cdd:PRK14956    6 EVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEIT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 NNHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK14956   86 KGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIP 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 162 ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGA 241
Cdd:PRK14956  166 ETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMIGY 245
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1489553191 242 IDRSVLEDFFQSLINQDEArlKERYAILENYETEGV 277
Cdd:PRK14956  246 HGIEFLTSFIKSLIDPDNH--SKSLEILESLYQEGQ 279
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
3-243 2.73e-65

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 217.82  E-value: 2.73e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLALKYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALmceegpkavpcdTCTQCQSALN 82
Cdd:PRK14970    6 VSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKI------------NQPGYDDPNE 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  83 NHHIDIIEMDGASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPA 162
Cdd:PRK14970   74 DFSFNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 163 TILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLGAI 242
Cdd:PRK14970  154 TILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNIL 233

                  .
gi 1489553191 243 D 243
Cdd:PRK14970  234 D 234
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
19-283 7.35e-53

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 182.10  E-value: 7.35e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  19 QESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCtQCQSALNNHHIDIIEM---DGAS 95
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQC-HSRLMAAGNHPDLLELnpeEKSD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  96 NRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKK 175
Cdd:COG0470    80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 176 IPENSVISHLKtileKEQVsyENSALEKLAHSGQGSLRDTITLLEQAINY------CDNAITESKVAEMLGAIDRSVLED 249
Cdd:COG0470   160 PSEEEALAWLR----EEGV--DEDALEAILRLAGGDPRAAINLLQALAGRkelledLAALLSRDRALELLDALLKAEALE 233
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1489553191 250 FFQSLINQ---------DEARLKERYAILEN---YETEGVLEEMML 283
Cdd:COG0470   234 LLDWLLKWlldnlpleyAGEDLARAYEALSEadrRLGRYANDRLLL 279
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
18-177 5.06e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 159.30  E-value: 5.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  18 GQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDI--IEMDGAS 95
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLviIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  96 NRgIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKK 175
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  ..
gi 1489553191 176 IP 177
Cdd:pfam13177 160 LS 161
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
24-213 1.72e-43

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 153.55  E-value: 1.72e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  24 KTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHID--IIEMDGASnRGIDD 101
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDlhRLEPEGQS-IKVDQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 102 VRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKKIPENSv 181
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEA- 159
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1489553191 182 ishLKTILEKEQVSYENSALekLAHSGQGSLR 213
Cdd:TIGR00678 160 ---LLQWLIRQGISEEAAEL--LLALAGGSPG 186
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
13-170 4.62e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 116.16  E-value: 4.62e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  13 FSELVGQESVAKTLS---------LALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEeGPKAVPCDTCTQCQSALNN 83
Cdd:PRK07940    4 WDDLVGQEAVVAELRaaaraaradVAAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCT-DPDEPGCGECRACRTVLAG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  84 HHIDI--IEMDGASnRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLP 161
Cdd:PRK07940   83 THPDVrvVAPEGLS-IGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVL 161

                  ....*....
gi 1489553191 162 ATILSRTQH 170
Cdd:PRK07940  162 PTIRSRCRH 170
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
19-206 1.17e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 110.79  E-value: 1.17e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  19 QESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDI--IEMDGASN 96
Cdd:PRK08058   11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVhlVAPDGQSI 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  97 RgIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEP-PSHVKFLLATTDALKLPaTILSRTQHFRFKK 175
Cdd:PRK08058   91 K-KDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPsGGTTAILLTENKHQILP-TILSRCQVVEFRP 168
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1489553191 176 IPENSVIshlkTILEKEQVSYENSALekLAH 206
Cdd:PRK08058  169 LPPESLI----QRLQEEGISESLATL--LAG 193
rfc PRK00440
replication factor C small subunit; Reviewed
7-261 3.30e-25

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 106.50  E-value: 3.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   7 KYRPKHFSELVGQESVAKTLSLALDNQRLANaYLFSGLRGSGKTSSSRIFARALMCEegpkavpcdtctqcqsalnNHHI 86
Cdd:PRK00440   10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELYGE-------------------DWRE 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  87 DIIEMDGASNRGIDDVRNLIEQ-TRYKPSFG-RYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATI 164
Cdd:PRK00440   70 NFLELNASDERGIDVIRNKIKEfARTAPVGGaPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPI 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 165 LSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLeQAINYCDNAITESKVAEMLGAIDR 244
Cdd:PRK00440  150 QSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKITGTARP 228
                         250
                  ....*....|....*....
gi 1489553191 245 SVLEDFFQSLINQD--EAR 261
Cdd:PRK00440  229 EEIREMIELALNGDftEAR 247
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
13-211 4.10e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 106.14  E-value: 4.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  13 FSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAvpcdtCTQCQsALNNHHIDII--- 89
Cdd:PRK07399    3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQGSPSK-----NIRRR-LEEGNHPDLLwve 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  90 ---------------EMDGASNRG-----IDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEpPSHVK 149
Cdd:PRK07399   77 ptyqhqgklitaseaEEAGLKRKAppqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGT 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1489553191 150 FLLATTDALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAhsgQGS 211
Cdd:PRK07399  156 LILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALA---QGS 214
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
6-261 4.78e-23

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 100.45  E-value: 4.78e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   6 LKYRPKHFSELVGQESVAKTLSLALDNQRLANaYLFSGLRGSGKTSSSRIFARALMCEegpkavPCDTCT---------- 75
Cdd:PRK12402    7 EKYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELYGD------PWENNFtefnvadffd 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  76 QCQSALNN--HHIDIIEMDGASNRGIDDVRNLI--EQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFL 151
Cdd:PRK12402   80 QGKKYLVEdpRFAHFLGTDKRIRSSKIDNFKHVlkEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 152 LATTDALKLPATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLeQAINYCDNAIT 231
Cdd:PRK12402  160 IATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTL-QTAALAAGEIT 238
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1489553191 232 ESKVAEMLGAIDRS-VLEDFFQSLINQDEAR 261
Cdd:PRK12402  239 MEAAYEALGDVGTDeVIESLLDAAEAGDFTD 269
PLN03025 PLN03025
replication factor C subunit; Provisional
7-224 6.07e-22

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 96.72  E-value: 6.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   7 KYRPKHFSELVG-QESVAKTLSLALDNQrLANaYLFSGLRGSGKTSSSRIFARALMceeGPkavpcdtctqcqsalnNHH 85
Cdd:PLN03025    6 KYRPTKLDDIVGnEDAVSRLQVIARDGN-MPN-LILSGPPGTGKTTSILALAHELL---GP----------------NYK 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  86 IDIIEMDGASNRGIDDVRNLIE---QTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPA 162
Cdd:PLN03025   65 EAVLELNASDDRGIDVVRNKIKmfaQKKVTLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIE 144
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1489553191 163 TILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRdtitlleQAIN 224
Cdd:PLN03025  145 PIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMR-------QALN 199
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
176-240 8.74e-21

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 86.02  E-value: 8.74e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489553191 176 IPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAITESKVAEMLG 240
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
4-240 3.06e-19

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 90.14  E-value: 3.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   4 LALKYRPKHFSELVGQESVA---KTLSLALDNQRLANAyLFSGLRGSGKTSSSRIFARALmceegpkavpcdtctqcqsa 80
Cdd:PRK13342    2 LAERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGAT-------------------- 60
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  81 lnNHHIDIIEmdgASNRGIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEppSHVKFLLATTD--AL 158
Cdd:PRK13342   61 --DAPFEALS---AVTSGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTEnpSF 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPENSVISHLKTILEKEQ---VSYENSALEKLAHSGQGSLRDTITLLEQAINYcDNAITESKV 235
Cdd:PRK13342  134 EVNPALLSRAQVFELKPLSEEDIEQLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELAALG-VDSITLELL 212

                  ....*
gi 1489553191 236 AEMLG 240
Cdd:PRK13342  213 EEALQ 217
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
28-215 1.30e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 87.23  E-value: 1.30e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  28 LALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEE-GPKAVPCDTCTQCQSALNNHHIDIIEMDGASNR--------- 97
Cdd:PRK08699   13 IAEHWERRPNAWLFAGKKGIGKTAFARFAAQALLCETpAPGHKPCGECMSCHLFGQGSHPDFYEITPLSDEpengrkllq 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  98 -GIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKKI 176
Cdd:PRK08699   93 iKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAP 172
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1489553191 177 PENSVISHLktileKEQVSYEnsALEKLAHSGQGSLRDT 215
Cdd:PRK08699  173 SHEEALAYL-----RERGVAE--PEERLAFHSGAPLFDE 204
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
30-173 1.26e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 84.37  E-value: 1.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  30 LDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHID---IIEMDGASNRGIDDVRNLI 106
Cdd:PRK05707   16 AGRGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDnfvLEPEEADKTIKVDQVRELV 95
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1489553191 107 EQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRF 173
Cdd:PRK05707   96 SFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQAC 162
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
29-202 7.71e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 81.70  E-value: 7.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  29 ALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVPCDTCTQCQSALNNHHIDIIEMDGASNR--GIDDVRNLI 106
Cdd:PRK06871   17 AFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdiGVDQVREIN 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 107 EQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKKIPENSVISHLK 186
Cdd:PRK06871   97 EKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWLIHPPEEQQALDWLQ 176
                         170
                  ....*....|....*.
gi 1489553191 187 TilekeQVSYENSALE 202
Cdd:PRK06871  177 A-----QSSAEISEIL 187
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
13-186 1.57e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 80.85  E-value: 1.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  13 FSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKavpcdtctqcqsalnnHHIDIIEMD 92
Cdd:PRK05564    3 FHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKILGKSQQR----------------EYVDIIEFK 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  93 GASNR--GIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQH 170
Cdd:PRK05564   67 PINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQI 146
                         170
                  ....*....|....*.
gi 1489553191 171 FRFKKIPENSVISHLK 186
Cdd:PRK05564  147 YKLNRLSKEEIEKFIS 162
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
12-171 4.38e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 79.46  E-value: 4.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  12 HFSELVgqeSVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAvPCDTCTQCQSALNNHHIDI--- 88
Cdd:PRK06090    4 DYPWLV---PVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQSE-ACGFCHSCELMQSGNHPDLhvi 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  89 -IEMDGASNRgIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSR 167
Cdd:PRK06090   80 kPEKEGKSIT-VEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSR 158

                  ....
gi 1489553191 168 TQHF 171
Cdd:PRK06090  159 CQQW 162
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
19-267 5.35e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 76.15  E-value: 5.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  19 QESVAKTLSlALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEeGPKAVPCDTCTQCQSAlnNHHIDIIEMDGASNRG 98
Cdd:PRK08769   10 QRAYDQTVA-ALDAGRLGHGLLICGPEGLGKRAVALALAEHVLAS-GPDPAAAQRTRQLIAA--GTHPDLQLVSFIPNRT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  99 IDDVRN--LIEQTR-------YKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQ 169
Cdd:PRK08769   86 GDKLRTeiVIEQVReisqklaLTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQ 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 170 HFRFKKIPENSVISHLKTilekeQVSYENSALEKL----AHSGQGS--LRDTITLLEQAInycdNAITESKVAEMLGAID 243
Cdd:PRK08769  166 RLEFKLPPAHEALAWLLA-----QGVSERAAQEALdaarGHPGLAAqwLREDGLALRRAV----AQDLEQIASGRAGAVD 236
                         250       260
                  ....*....|....*....|....
gi 1489553191 244 RSvledffQSLINQDEARLKERYA 267
Cdd:PRK08769  237 VA------QRWTNDGQADQRLRHA 254
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
38-167 5.82e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 76.26  E-value: 5.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  38 AYLFSGLRGSGktSSSRIFA--RALMCE--EGPKAvpCDTCTQCQSALNNHHIDIIEMD---GASNRGIDDVRNLIEQTR 110
Cdd:PRK07993   26 ALLIQALPGMG--DDALIYAlsRWLMCQqpQGHKS--CGHCRGCQLMQAGTHPDYYTLTpekGKSSLGVDAVREVTEKLY 101
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1489553191 111 YKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSR 167
Cdd:PRK07993  102 EHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
34-171 9.94e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 75.57  E-value: 9.94e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  34 RLANAYLFSGLRGSGKTSSSRIFARALMCEE-GPKAVPCDTCTQCQSALNNHHID-------IIEMDGASNRG------- 98
Cdd:PRK06964   19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETpQPDGEPCGTCAACNWFAQGNHPDyrivrpeALAAEAPGAADeakeada 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  99 ---------------IDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPAT 163
Cdd:PRK06964   99 deggkktkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178

                  ....*...
gi 1489553191 164 ILSRTQHF 171
Cdd:PRK06964  179 ILSRCRQF 186
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
16-267 1.25e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 72.38  E-value: 1.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  16 LVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMCEEGPKAVP-------CDTCTQCQSALNNHH--- 85
Cdd:PRK09112   25 LFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAEAPetladpdPASPVWRQIAQGAHPnll 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  86 -----IDiiEMDGASNRGI--DDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDAL 158
Cdd:PRK09112  105 hitrpFD--EKTGKFKTAItvDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSG 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 159 KLPATILSRTQHFRFKKIPEN---SVISHL-----------KTILEKEQVSYENSALekLAHSGQGSLRDTI-TLLEQAI 223
Cdd:PRK09112  183 RLLPTIRSRCQPISLKPLDDDelkKALSHLgssqgsdgeitEALLQRSKGSVRKALL--LLNYGGLEIIATIdQLLAGSG 260
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1489553191 224 nyCDNAITEsKVAEMLGAIDRSVLEDFFQSLIN---QDEAR---------LKERYA 267
Cdd:PRK09112  261 --PDARKAH-KLADALSGRESEVQFDFFRDHLLdriMAEARraaeagdlaLAERLA 313
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
19-175 1.29e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 71.59  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  19 QESVAKTLSLALDNQRLANAYLFSGLRGSGKTSssRIFARALMCEEGPKAVPCDTCTQCQSALNNHHID--IIEMDGASN 96
Cdd:PRK07276    7 QPKVFQRFQTILEQDRLNHAYLFSGDFASFEMA--LFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDvtVIEPQGQVI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  97 RgIDDVRNLIE---QTRYKpsfGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVK-FLLATTDALKLPaTILSRTQHFR 172
Cdd:PRK07276   85 K-TDTIRELVKnfsQSGYE---GKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYiFLLTNDENKVLP-TIKSRTQIFH 159

                  ...
gi 1489553191 173 FKK 175
Cdd:PRK07276  160 FPK 162
44 PHA02544
clamp loader, small subunit; Provisional
7-276 7.03e-13

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 69.63  E-value: 7.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   7 KYRPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSsrifARALmCEEgpkavpcdtctqcqsaLNnhhI 86
Cdd:PHA02544   14 KYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTV----AKAL-CNE----------------VG---A 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  87 DIIEMDGASNRgIDDVRNliEQTRYKPS---FGRYKIFIIDEVHMFTTEAFNALLKTL-EEPPSHVKFLLATTDALKLPA 162
Cdd:PHA02544   70 EVLFVNGSDCR-IDFVRN--RLTRFASTvslTGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIE 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 163 TILSRTQHFRF------KKIPENS-VISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLEqainycDNAITESKV 235
Cdd:PHA02544  147 PLRSRCRVIDFgvptkeEQIEMMKqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQ------RYASTGKID 220
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1489553191 236 AEMLGAIDRSVLEDFFQSLINQDEARLKeryAILENYETEG 276
Cdd:PHA02544  221 AGILSEVTNSDIDDVVEALKAKDFKAVR---ALAPNYANDY 258
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
9-219 2.14e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 68.90  E-value: 2.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   9 RPKHFSELVGQESVAKTLSLALDNQRLANAYLFSGLRGSGKTSSSRIFARALMC---EEGPKAVPCDTCTQCQ------- 78
Cdd:PRK07471   14 HPRETTALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLAtppPGGDGAVPPPTSLAIDpdhpvar 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  79 --SALNNHHIDIIEMdGASNRG--------IDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHV 148
Cdd:PRK07471   94 riAAGAHGGLLTLER-SWNEKGkrlrtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARS 172
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1489553191 149 KFLLATTDALKLPATILSRTQHFRFKKIPENSVIShlktILEKEQVSYENSALEKLAHSGQGSLRDTITLL 219
Cdd:PRK07471  173 LFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVID----ALAAAGPDLPDDPRAALAALAEGSVGRALRLA 239
PRK04195 PRK04195
replication factor C large subunit; Provisional
5-267 3.41e-12

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 68.79  E-value: 3.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   5 ALKYRPKHFSELVGQESVAKTLSL---ALDNQRLANAYLFSGLRGSGKTSSsrifARALMCEEGpkavpcdtctqcqsal 81
Cdd:PRK04195    5 VEKYRPKTLSDVVGNEKAKEQLREwieSWLKGKPKKALLLYGPPGVGKTSL----AHALANDYG---------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  82 nnhhIDIIEMDgASnrgidDVRNL--IEQT-----RYKPSFG-RYKIFIIDEV-HMFTTE---AFNALLKTLEEPPSHVk 149
Cdd:PRK04195   65 ----WEVIELN-AS-----DQRTAdvIERVageaaTSGSLFGaRRKLILLDEVdGIHGNEdrgGARAILELIKKAKQPI- 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 150 fLLATTDALKLP-ATILSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLeQAINYCDN 228
Cdd:PRK04195  134 -ILTANDPYDPSlRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDL-QAIAEGYG 211
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1489553191 229 AITESKVAEMLgaiDRSVLEDFFQSLInqdeARLKERYA 267
Cdd:PRK04195  212 KLTLEDVKTLG---RRDREESIFDALD----AVFKARNA 243
PRK04132 PRK04132
replication factor C small subunit; Provisional
87-235 3.09e-11

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 66.40  E-value: 3.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  87 DIIEMDGASNRGIDDVRNLIEQ-TRYKPSFG-RYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATI 164
Cdd:PRK04132  598 NFLELNASDERGINVIREKVKEfARTKPIGGaSFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPI 677
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1489553191 165 LSRTQHFRFKKIPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLeQAINYCDNAITESKV 235
Cdd:PRK04132  678 QSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINIL-QAAAALDDKITDENV 747
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
99-196 8.69e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 63.28  E-value: 8.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  99 IDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRfkkIPE 178
Cdd:PRK05917   77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIH---IPM 153
                          90
                  ....*....|....*...
gi 1489553191 179 NSvishlKTILEKEQVSY 196
Cdd:PRK05917  154 EE-----KTLVSKEDIAY 166
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
17-173 5.76e-09

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 55.23  E-value: 5.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  17 VGQESVAKTLSLALDNQRLANaYLFSGLRGSGKTSSSRIFARALMCEEGPkavpcdtctqcqsalnnhhidIIEMDGASN 96
Cdd:cd00009     1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELFRPGAP---------------------FLYLNASDL 58
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  97 RGIDDVRNLIEQTRYKPSFGR-----YKIFIIDEVHMFTTEAFNALLKTLEE------PPSHVKFLLATTDAL--KLPAT 163
Cdd:cd00009    59 LEGLVVAELFGHFLVRLLFELaekakPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPLlgDLDRA 138
                         170
                  ....*....|.
gi 1489553191 164 ILSR-TQHFRF 173
Cdd:cd00009   139 LYDRlDIRIVI 149
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
111-270 2.27e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 55.88  E-value: 2.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 111 YKPSF--GRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFKKIPENSVISHLkti 188
Cdd:PRK07132   82 YFSSFvqSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKL--- 158
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 189 LEKEQVSYENSALEKLAHSgqgslrdtitlLEQAINYcDNAITESKVAEMLGAIDRSVLEDFfqSLINQDEARL-KERYA 267
Cdd:PRK07132  159 LSKNKEKEYNWFYAYIFSN-----------FEQAEKY-INKESENLLKKFEEALNKSLKEKY--ELILFLNKKLtKENAL 224

                  ...
gi 1489553191 268 ILE 270
Cdd:PRK07132  225 FLL 227
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
99-230 3.94e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 53.88  E-value: 3.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  99 IDDVRNLIEQTRYKPSfgRYKIFIIdEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILSRTQHFRFK-KIP 177
Cdd:PRK08485   39 IEDAKEVIAEAYIAES--EEKIIVI-AAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRKqKKP 115
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1489553191 178 ENSVISHLKTI-----------LEKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYCDNAI 230
Cdd:PRK08485  116 VKPLDLDLKKLdlkdiyeflkeLEKENKLSKEELKELIESLLKECVKYKIPLNEEELEYFDKAI 179
PRK13341 PRK13341
AAA family ATPase;
4-223 5.98e-07

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 52.36  E-value: 5.98e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   4 LALKYRPKHFSELVGQESV---AKTLSLALDNQRLANAyLFSGLRGSGKTSSSRIFARAlmceegpkavpcdtcTQCQ-S 79
Cdd:PRK13341   18 LADRLRPRTLEEFVGQDHIlgeGRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANH---------------TRAHfS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  80 ALNnhhidiiemdgASNRGIDDVRNLIEQTRYK-PSFGRYKIFIIDEVHMFTTEAFNALLKTLEEppSHVKFLLATTD-- 156
Cdd:PRK13341   82 SLN-----------AVLAGVKDLRAEVDRAKERlERHGKRTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnp 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 157 ------ALklpatiLSRTQHFRFKKIPENSVISHLKTILEKEQVSY-------ENSALEKLAHSGQGSLRDTITLLEQAI 223
Cdd:PRK13341  149 yfevnkAL------VSRSRLFRLKSLSDEDLHQLLKRALQDKERGYgdrkvdlEPEAEKHLVDVANGDARSLLNALELAV 222
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
3-249 3.02e-05

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 46.38  E-value: 3.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   3 VLALKYRPkhfSELVG----QESVAKTLSLALDNQRLANAYLFsGLRGSGKTSSSRIFARALMCEEGPKAVPCDT----C 74
Cdd:COG1474    18 VLSPDYVP---DRLPHreeeIEELASALRPALRGERPSNVLIY-GPTGTGKTAVAKYVLEELEEEAEERGVDVRVvyvnC 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  75 TQCQS---ALnnHHI--DIIEMDGASNRGI--DDVRNLIeqTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTL-----E 142
Cdd:COG1474    94 RQASTryrVL--SRIleELGSGEDIPSTGLstDELFDRL--YEALDERDGVLVVVLDEIDYLVDDEGDDLLYQLlraneE 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 143 EPPSHVKFLLATTDaLKLPATILSRTQ-HFRFKKI---PENSviSHLKTILE-------KEQVsYENSALEKLA-HSGQ- 209
Cdd:COG1474   170 LEGARVGVIGISND-LEFLENLDPRVKsSLGEEEIvfpPYDA--DELRDILEdraelafYDGV-LSDEVIPLIAaLAAQe 245
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1489553191 210 -GSLRDTITLLEQAINYCDNA----ITESKVAEMLGAIDRSVLED 249
Cdd:COG1474   246 hGDARKAIDLLRVAGEIAEREgsdrVTEEHVREAREKIERDRLLE 290
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
115-350 3.54e-05

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 46.01  E-value: 3.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 115 FGRYKIFIIDEVHMFT--TEAFNALLKTLEEPPSHVKFLLATTD---ALKLPATILSRTQHFRFKKIPENSVISHLKTIL 189
Cdd:COG1466    60 FGERRLVIVRNAEFLKkpGEGLEALEAYLANPPPDTVLVLTAGKldkRKKLFKALEKAGVVVECYPLKERELPAWIRQRL 139
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 190 EKEQVSYENSALEKLAHSGQGSLRDTITLLEQAINYC--DNAITESKVAEMLGAIDRSVLEDFFQSLINQDEARLkerYA 267
Cdd:COG1466   140 KAAGLRIDPDAAQLLAERVGGDLLALAQELEKLALYAgdGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARA---LR 216
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191 268 ILENYETEGvlEEMMLFLKAkllspdsysillIERFFKIIMSSLSLLKEGANASFVLLLLKM------KFKEALK---LK 338
Cdd:COG1466   217 ILRRLLAEG--EEPVLILAA------------LARQFRLLLQVKALLAQGKSLAEIAKELGVppfrvkLALRALRrwsLE 282
                         250
                  ....*....|..
gi 1489553191 339 ALDDAILELEQT 350
Cdd:COG1466   283 RLARALQLLAEA 294
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
39-152 5.54e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 43.52  E-value: 5.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191   39 YLFSGLRGSGKTSSSRIFARALMCEEGP-KAVPCDTCTQCQSALNNHHidIIEMDGASNRGIDDVRNLIEQTRYKpsfgR 117
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGvIYIDGEDILEEVLDQLLLI--IVGGKKASGSGELRLRLALALARKL----K 78
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1489553191  118 YKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLL 152
Cdd:smart00382  79 PDVLILDEITSLLDAEQEALLLLLEELRLLLLLKS 113
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
176-237 5.88e-05

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 40.98  E-value: 5.88e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1489553191 176 IPENSVISHLKTILEKEQVSYENSALEKLAHSGQGSLRDTITLLeQAINYCDNAITESKVAE 237
Cdd:cd18140     1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYE 61
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
39-174 7.77e-05

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 42.58  E-value: 7.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  39 YLFSGLRGSGKTSSSRIFARALmceegpkavpcdtctqcqsalnnhHIDIIEMDGASNRGI------DDVRNLIEQTR-Y 111
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKEL------------------------GAPFIEISGSELVSKyvgeseKRLRELFEAAKkL 56
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1489553191 112 KPSfgrykIFIIDEVH-----------MFTTEAFNALLKTLEEP---PSHVKFLLATTDALKLPATILSRTQHFRFK 174
Cdd:pfam00004  57 APC-----VIFIDEIDalagsrgsggdSESRRVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRFDRIIEF 128
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
56-167 2.24e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 43.28  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  56 FARALMCEEGPKavPCDTCTQCQSALNNHHIDIIEMDGASN----RGIDDVRNLIEQTRYKpSFGRyKIFIIDEVHMFTT 131
Cdd:PRK05818   27 YLTSIVCTKANG--FCKTCESCLKILNGKYNDFYLIFDQKNpikkEDALSIINKLNRPSVE-SNGK-KIYIIYGIEKLNK 102
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1489553191 132 EAFNALLKTLEEPPSHVKFLLATTDALKLPATILSR 167
Cdd:PRK05818  103 QSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSR 138
AAA_22 pfam13401
AAA domain;
36-160 2.05e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 38.48  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  36 ANAYLFSGLRGSGKTSSSRIFARALmCEEGPKAVPCDtCTQ--CQSALNNHHIDIIEMDGASNRGIDDVRNLIEQTRYKP 113
Cdd:pfam13401   5 AGILVLTGESGTGKTTLLRRLLEQL-PEVRDSVVFVD-LPSgtSPKDLLRALLRALGLPLSGRLSKEELLAALQQLLLAL 82
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1489553191 114 sfGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLA-TTDALKL 160
Cdd:pfam13401  83 --AVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILVgTPELREL 128
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
9-60 2.57e-03

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 39.02  E-value: 2.57e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1489553191   9 RPKHFSELVGQESVAKTLSLALDNQRLANA----YLFSGLRGSGKTSSSRIFARAL 60
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKQRGEaldhVLLYGPPGLGKTTLANIIANEM 57
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
90-167 4.67e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 39.06  E-value: 4.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489553191  90 EMDGASNR---GIDDVRNLIEQTRYKPSFGRYKIFIIDEVHMFTTEAFNALLKTLEEPPSHVKFLLATTDALKLPATILS 166
Cdd:PRK06581   59 ETSATSNAkniSIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRS 138

                  .
gi 1489553191 167 R 167
Cdd:PRK06581  139 R 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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