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Conserved domains on  [gi|1466411749|gb|RGH68659|]
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carbohydrate ABC transporter permease [Ruminococcus sp. AM29-5AC]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 10-278 1.84e-80

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 244.23  E-value: 1.84e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFKKKAYI-SKAPFEIPTGkmyVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIIL 88
Cdd:COG0395    16 LLYLLLILLALLFLFPLYWMVVTSFKPPAEIfSGPPSLLPSE---FTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  89 CCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGN-PWGLIVIYLGFGAGLSVFMFTGFMKSIPL 167
Cdd:COG0395    93 LSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNtYWGLILPYLAFGLPFGIFLLRQFFRSIPR 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 168 EIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKYKTVPMAVQYLKGGYGsVDMGAMMG 247
Cdd:COG0395   173 ELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG-TDWGLLMA 251

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1466411749 248 TLVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:COG0395   252 AAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 10-278 1.84e-80

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 244.23  E-value: 1.84e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFKKKAYI-SKAPFEIPTGkmyVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIIL 88
Cdd:COG0395    16 LLYLLLILLALLFLFPLYWMVVTSFKPPAEIfSGPPSLLPSE---FTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  89 CCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGN-PWGLIVIYLGFGAGLSVFMFTGFMKSIPL 167
Cdd:COG0395    93 LSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNtYWGLILPYLAFGLPFGIFLLRQFFRSIPR 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 168 EIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKYKTVPMAVQYLKGGYGsVDMGAMMG 247
Cdd:COG0395   173 ELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG-TDWGLLMA 251

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1466411749 248 TLVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:COG0395   252 AAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
75-278 1.41e-19

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 86.30  E-value: 1.41e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  75 SLFITILSVAVIILCCSMCAWYICRVKTKFTKILymlcLFAMIVpFQMEMFTLSKIA-----NMLHMGNPW-------GL 142
Cdd:PRK10998   88 SVKVAGITAIGIVALSTTCAYAFARMRFKGKATL----LKGMLI-FQMFPAVLSLVAlyalfDRLGQYIPFiglnthgGV 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 143 IVIYLGfGAGLSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVL-DQR 221
Cdd:PRK10998  163 IFAYLG-GIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLrDVN 241

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1466411749 222 KYKTVPMAVQYL-KGGYGSVDMGAMMgtlVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:PRK10998  242 SYTLAVGMQQYLnPQNYLWGDFAAAA---VLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-257 2.90e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.84  E-value: 2.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  72 FGWSLFITILSVAVIILCCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGNPWGL-----IVIY 146
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGlglpaLILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 147 LGFGAGLSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLdQRKYKTV 226
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG-GGEAPGP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1466411749 227 PMAVQYLKGGYGSVDMGAMMGTLVLAIVPII 257
Cdd:cd06261   160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 99-262 8.73e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.84  E-value: 8.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  99 RVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMG-NPWGLIVIYLGFGAGLSVFMFTGFMKSIPLEIEEAAMIDG 177
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 178 CTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLdqrkykTVPMAVQYLKGGYGSVDMGAMMGTLVLAIVPII 257
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG------SWPGLGLLLIEAILGYDYPEIQGPVLAAALILL 164


                  ....*
gi 1466411749 258 IFYLF 262
Cdd:pfam00528 165 LLNLL 169
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 7-268 6.26e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.15  E-value: 6.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749   7 HGTLLTIIFAVLSLLYVYPIILVFINSFKKKAyiskapfeiptgKMYVGLENYIRGIKQTGLIQAFGWSLFITILSVAVI 86
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLLPLLALLTKSVYDSD------------GDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  87 ILCCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKI-------ANMLHMGNPWGLIVIYLG--FGAGLSVFM 157
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLfgnqgllKGLLGGFSIYGFWGIVIGevFYTFPHALM 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 158 --FTGFmKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQrkYKTVPMAVQYLKG 235
Cdd:TIGR03262 151 ilVTAL-SLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGD--YNVLATDIYKQVI 227

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1466411749 236 GYGSVDMGAMMGTLVLaiVPiIIFYLFCQRYII 268
Cdd:TIGR03262 228 GQQNFPMGAVVGVLLL--LP-ALLAFGIDRAIQ 257
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 10-278 1.84e-80

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 244.23  E-value: 1.84e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFKKKAYI-SKAPFEIPTGkmyVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIIL 88
Cdd:COG0395    16 LLYLLLILLALLFLFPLYWMVVTSFKPPAEIfSGPPSLLPSE---FTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  89 CCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGN-PWGLIVIYLGFGAGLSVFMFTGFMKSIPL 167
Cdd:COG0395    93 LSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNtYWGLILPYLAFGLPFGIFLLRQFFRSIPR 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 168 EIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKYKTVPMAVQYLKGGYGsVDMGAMMG 247
Cdd:COG0395   173 ELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG-TDWGLLMA 251

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1466411749 248 TLVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:COG0395   252 AAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 9-278 6.04e-47

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 158.01  E-value: 6.04e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749   9 TLLTIIFAVLSLLYVYPIILVFINSFKKKAYISKAPFeIPTGkmyVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIIL 88
Cdd:COG3833    16 GLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSL-IPEN---FTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  89 CCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHM-GNPWGLIVIYLGFGAGLSVFMFTGFMKSIPL 167
Cdd:COG3833    92 LAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLlNTLLGLILVYLGGAIPFNTWLMKGYFDTIPK 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 168 EIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKYKTVPMAVQYLKGGYGSVDMGAMMG 247
Cdd:COG3833   172 ELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRNTNWGVFAA 251

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1466411749 248 TLVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:COG3833   252 GAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
75-278 1.41e-19

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 86.30  E-value: 1.41e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  75 SLFITILSVAVIILCCSMCAWYICRVKTKFTKILymlcLFAMIVpFQMEMFTLSKIA-----NMLHMGNPW-------GL 142
Cdd:PRK10998   88 SVKVAGITAIGIVALSTTCAYAFARMRFKGKATL----LKGMLI-FQMFPAVLSLVAlyalfDRLGQYIPFiglnthgGV 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 143 IVIYLGfGAGLSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVL-DQR 221
Cdd:PRK10998  163 IFAYLG-GIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLrDVN 241

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1466411749 222 KYKTVPMAVQYL-KGGYGSVDMGAMMgtlVLAIVPIIIFYLFCQRYIIEGVVAGAVKG 278
Cdd:PRK10998  242 SYTLAVGMQQYLnPQNYLWGDFAAAA---VLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
15-261 9.39e-18

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 80.95  E-value: 9.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  15 FAVLSLLYVYPIILVFINSFKKKAYISKAPFeiptgkmYVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIILCCSMCA 94
Cdd:COG1175    28 LLLLLVFVLYPLLYTLYLSFTDWNLLGPPPE-------FVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  95 WYICRvKTKFTKILYMLCLFAMIVP-----------FQMEMFTLSKIANMLHMGNP----------WGLIVIYLGFGAGL 153
Cdd:COG1175   101 LLLNR-KLRGRGFFRTLFFLPWVISpvvvaliwkwlFNPDYGLLNALLGALGLEPInwlgdpslalPAVIIVTVWKGTGF 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 154 SVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLP-----------SLVLDQRK 222
Cdd:COG1175   180 NMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVyvltgggpgnsTTTLVLYI 259

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1466411749 223 YKTvpmAVQYLKGGYGSvdmgAMMGTLVLAIVPIIIFYL 261
Cdd:COG1175   260 YQT---AFQQFDFGYAS----AIAVVLFLIILVLTLLQL 291
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 4-265 2.97e-17

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 79.00  E-value: 2.97e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749   4 KVKHGTLLTIIFAVLSLLYVY-PIILVFINSFKKKAYISKapfeIPTGkmyVGLENYIRGIKQTGLIQAFGWSLFITILS 82
Cdd:COG1177     1 SSRLGRLLLRLFLALVLLFLYlPILVLVLYSFNDSWFLTF----PPEG---FTLRWYAELFSDPRLLDALLNSLLIALLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  83 VAVIILCCSMCAWYICRVKTKFTKILYMLCLFAMIVP-FQMEMFTLSKIANMLHMGNPWGLIVIYLGFGAGLSVFMFTGF 161
Cdd:COG1177    74 TLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPgIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLAR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 162 MKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRkYKTVPMAV-QYLKGGYgSV 240
Cdd:COG1177   154 LQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPG-VTTLPVYIySMIRRGI-SP 231

                         250       260
                  ....*....|....*....|....*
gi 1466411749 241 DMGAMMGTLVLAIVPIIIFYLFCQR 265
Cdd:COG1177   232 EINALSTLLILLSLLLLLLAERLRR 256
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 10-259 2.63e-14

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 71.33  E-value: 2.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFKKKAYISKAPFEIptgkmyvGLENYIRGIKQTGLIQAFGWSLFITILSVAVIILC 89
Cdd:COG1176    14 LLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF-------TLENYARLFTDPLYLKVLLRTLWIALLTTLICLLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  90 CSMCAWYICRVKTKFTKILYMLCLFAMIVPF----QMEMFTLSK---IANMLH-----------MGNPWGLIV----IYL 147
Cdd:COG1176    87 GYPIAYFLARAPPRWRNLLLLLVILPFWTSFlvrtYAWIVLLGRnglLNSLLLalglideplrlLYTEFAVVIglvyVYL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 148 GFgaglSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLvLDQRKYKTVP 227
Cdd:COG1176   167 PF----MVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPAL-LGGGKVLMIG 241

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1466411749 228 MAVQYLKGGYGSVDMGAMMGTLVLAIVPIIIF 259
Cdd:COG1176   242 NLIYQQFLSALNWPLAAALAVVLLLIVLLVLL 273
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
10-259 9.91e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 70.58  E-value: 9.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFkkkayiskapfeiptgkmYVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIILC 89
Cdd:COG1178    12 LLLLLALLLALLVLLPLLALLLRAF------------------TDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  90 CSMCAWYICRVKTKFTKILYMLCLFAMIVP--------------------FQMEMFTLSkianMLHMGNPWGLIVIYLGF 149
Cdd:COG1178    74 GVPLAWLLARTDFPGRRLLRWLLLLPLALPpyvvalawialfgpngllntLLRALFGLE----PPDIYGLGGIILVLVLF 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 150 GAGLSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVldQRKYKTVPMA 229
Cdd:COG1178   150 NYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGYTTLTTA 227

                         250       260       270
                  ....*....|....*....|....*....|
gi 1466411749 230 VQYLKGGYGSVDMGAMMGTLVLAIVPIIIF 259
Cdd:COG1178   228 IYQAWLGDFDLGAAAALALVLLLLVLLLLL 257
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
20-272 1.06e-13

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 69.38  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  20 LLYVYPIILVFINSFKKKAYISKAPFE-IPTGKMYVGLEN-YIRGIKQTG------LIQAFGWSLFITILSVAVIILCcs 91
Cdd:PRK10973   21 AVILFPLYVAFVAATLDKQAVFAVPMTlIPGTHLLENIANiWVNGVGNNSapfgrmLLNSFVMAFSITVGKITVSMLS-- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  92 mcAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGNPWGLIVIYLgFGAGLSVFMFTGFMKSIPLEIEE 171
Cdd:PRK10973   99 --AFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPL-MASATATFLFRQFFMTLPDELVE 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 172 AAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKYKTVPMAVQ-YLKGGYGSVDMGAMMGTLV 250
Cdd:PRK10973  176 AARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKgMIATGEGTTEWNQVMAAML 255

                         250       260
                  ....*....|....*....|..
gi 1466411749 251 LAIVPIIIFYLFCQRYIIEGVV 272
Cdd:PRK10973  256 LTLIPPVVIVLAMQRAFVRGLV 277
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
10-262 2.04e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 69.80  E-value: 2.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  10 LLTIIFAVLSLLYVYPIILVFINSFkkkayiskapfeIPTGKMYVGLENYIRGIKQTGLIQAFGWSLFITILSVAVIILC 89
Cdd:COG1178   290 ALALCLLLVLLGLLLPLLALLLWSL------------TKALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  90 CSMCAWYICRVKTKFTKILYMLCLFAMIVP-------FqmeMFTLSKIANMLHMGNPWGLIVIY------LGFGAGLSVf 156
Cdd:COG1178   358 ALLLAYLVRRRRGRLARLLDRLAMLPYAVPgivlglgL---LLLFNRPLPLLLYGTLAILVLAYvvrflpFALRSLEAA- 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 157 mftgfMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDylLP-SLVLDQRKYKTVPMAV-QYLk 234
Cdd:COG1178   434 -----LAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKE--LSaTLLLRPPGFETLAVLIyQLA- 505

                         250       260
                  ....*....|....*....|....*...
gi 1466411749 235 gGYGSVDMGAMMGTLVLAIVpIIIFYLF 262
Cdd:COG1178   506 -SSGRYGEAAALALLLVLVS-LLPVLLL 531
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 72-257 2.90e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.84  E-value: 2.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  72 FGWSLFITILSVAVIILCCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMGNPWGL-----IVIY 146
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGlglpaLILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 147 LGFGAGLSVFMFTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLdQRKYKTV 226
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG-GGEAPGP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1466411749 227 PMAVQYLKGGYGSVDMGAMMGTLVLAIVPII 257
Cdd:cd06261   160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 99-262 8.73e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.84  E-value: 8.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  99 RVKTKFTKILYMLCLFAMIVPFQMEMFTLSKIANMLHMG-NPWGLIVIYLGFGAGLSVFMFTGFMKSIPLEIEEAAMIDG 177
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 178 CTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLdqrkykTVPMAVQYLKGGYGSVDMGAMMGTLVLAIVPII 257
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG------SWPGLGLLLIEAILGYDYPEIQGPVLAAALILL 164


                  ....*
gi 1466411749 258 IFYLF 262
Cdd:pfam00528 165 LLNLL 169
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 1-202 3.31e-08

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 53.22  E-value: 3.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749   1 MNKKVKHGTLLTIIF--AVLSLLYVYPIILVFINSFKkkayiskapfeiptgkmyVGLENYIRGIKQTGLIQAFGWSLFI 78
Cdd:COG0555     1 MSRRVLPGFGLTLGLtlLYLSLIVLLPLAALVLKAAG------------------LGWAEFWAVLTSPRVLAALKLSLGT 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  79 TILSVAVIILCCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKI-ANMLHMGN---PWGLIVIYLGFGAGLS 154
Cdd:COG0555    63 ALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLfGPNGWLGQllaPLGIKVAFTPLGIVLA 142

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1466411749 155 VFmFTGF----------MKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTIL 202
Cdd:COG0555   143 QT-FVSLpfvvrtvqpvLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFAL 199
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 7-268 6.26e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 53.15  E-value: 6.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749   7 HGTLLTIIFAVLSLLYVYPIILVFINSFKKKAyiskapfeiptgKMYVGLENYIRGIKQTGLIQAFGWSLFITILSVAVI 86
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLLPLLALLTKSVYDSD------------GDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749  87 ILCCSMCAWYICRVKTKFTKILYMLCLFAMIVPFQMEMFTLSKI-------ANMLHMGNPWGLIVIYLG--FGAGLSVFM 157
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLfgnqgllKGLLGGFSIYGFWGIVIGevFYTFPHALM 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 158 --FTGFmKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQrkYKTVPMAVQYLKG 235
Cdd:TIGR03262 151 ilVTAL-SLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGD--YNVLATDIYKQVI 227

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1466411749 236 GYGSVDMGAMMGTLVLaiVPiIIFYLFCQRYII 268
Cdd:TIGR03262 228 GQQNFPMGAVVGVLLL--LP-ALLAFGIDRAIQ 257
malF PRK10999
maltose ABC transporter permease MalF;
142-194 1.84e-04

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 42.64  E-value: 1.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1466411749 142 LIV-IYLGFGAGLSVFMftGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLP-IAKP 194
Cdd:PRK10999  379 LIVnTWLGYPYMMILCM--GLLKAIPDDLYEASAMDGAGPFQNFFKITLPlLIKP 431
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 169-259 5.51e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 37.52  E-value: 5.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1466411749 169 IEEAAMIDGCTPIQTFFKVVLPIAKPTCVTVTILQAMWIWNDYLLPSLVLDQRKyKTVPMAVqylkggYGSVDMGA---- 244
Cdd:PRK10592  170 IEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFVSGPGA-TTLPMLV------FSSVRMGVnpei 242

                          90
                  ....*....|....*.
gi 1466411749 245 -MMGTLVLAIVPIIIF 259
Cdd:PRK10592  243 nALATLILGVVGIVGF 258
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
158-194 6.76e-03

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 37.50  E-value: 6.76e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1466411749 158 FTGFMKSIPLEIEEAAMIDGCTPIQTFFKVVLPIAKP 194
Cdd:PRK10561  162 FFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAP 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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