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Conserved domains on  [gi|1938964377|gb|QPK41155|]
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alpha-amylase inhibitor [Solanum sucrense]

Protein Classification

AAI_LTSS domain-containing protein( domain architecture ID 10627303)

AAI_LTSS domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LTP_2 pfam14368
Probable lipid transfer; The members of this family are probably involved in lipid transfer. ...
 10-107 5.43e-15

Probable lipid transfer; The members of this family are probably involved in lipid transfer. The family has several highly conserved cysteines, paired in various ways.


:

Pssm-ID: 433909  Cd Length: 100  Bit Score: 67.51  E-value: 5.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  10 LSCIIVLAILPINAQIVTSPCTATMLTSFTPCLNFLSNGNGTATPSPGCCNAL*TMMGNGSACLCVIASGGIPFHIPINP 89
Cdd:pfam14368   1 LALALAAQAPAPPPAPAAASCTLSMLSGLSPCLPYLTGTPAATAPSPACCGALKSAVSTDVTCLCALVTAPLPIGFPINV 80

                          90
                  ....*....|....*...
gi 1938964377  90 NTTMSLPRACNMARVPLQ 107
Cdd:pfam14368  81 TRALALPRACGVKTPPSS 98
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
77-189 2.03e-06

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14971:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 614  Bit Score: 47.46  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  77 ASGGIPFHIPINPNTTMSLPracnmarvPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKgttafnPMSPTLAPQ 156
Cdd:PRK14971  369 ASGGRGPKQHIKPVFTQPAA--------APQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPP------TVSVDPPAA 434

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1938964377 157 ADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVG 189
Cdd:PRK14971  435 VPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLG 467
 
Name Accession Description Interval E-value
LTP_2 pfam14368
Probable lipid transfer; The members of this family are probably involved in lipid transfer. ...
 10-107 5.43e-15

Probable lipid transfer; The members of this family are probably involved in lipid transfer. The family has several highly conserved cysteines, paired in various ways.


Pssm-ID: 433909  Cd Length: 100  Bit Score: 67.51  E-value: 5.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  10 LSCIIVLAILPINAQIVTSPCTATMLTSFTPCLNFLSNGNGTATPSPGCCNAL*TMMGNGSACLCVIASGGIPFHIPINP 89
Cdd:pfam14368   1 LALALAAQAPAPPPAPAAASCTLSMLSGLSPCLPYLTGTPAATAPSPACCGALKSAVSTDVTCLCALVTAPLPIGFPINV 80

                          90
                  ....*....|....*...
gi 1938964377  90 NTTMSLPRACNMARVPLQ 107
Cdd:pfam14368  81 TRALALPRACGVKTPPSS 98
AAI_LTSS cd00010
AAI_LTSS: Alpha-Amylase Inhibitors (AAI), Lipid Transfer (LT) and Seed Storage (SS) Protein ...
 38-101 1.59e-08

AAI_LTSS: Alpha-Amylase Inhibitors (AAI), Lipid Transfer (LT) and Seed Storage (SS) Protein family; a protein family unique to higher plants that includes cereal-type alpha-amylase inhibitors, lipid transfer proteins, seed storage proteins, and similar proteins. Proteins in this family are known to play important roles, in defending plants from insects and pathogens, lipid transport between intracellular membranes, and nutrient storage. Many proteins of this family have been identified as allergens in humans. These proteins contain a common pattern of eight cysteines that form four disulfide bridges.


Pssm-ID: 237980  Cd Length: 63  Bit Score: 49.35  E-value: 1.59e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1938964377  38 FTPCLNFLSNGNgtATPSPGCCNAL*TMMGNGSACLC-VIASGGIPFHIPINPNTTMSLPRACNM 101
Cdd:cd00010     1 LAPCLSYLTGGA--TAPPSDCCSGLKSVVKSDPKCLCaALNGPGASLLGLKNATRALALPAACGL 63
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 30-108 9.42e-07

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 45.06  E-value: 9.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377   30 CTATMLtSFTPCLNFLSNGNGTATPSPGCCNAL*TMmgNGSACLC---VIASGGIPFHIPINPNTTMSLPRACNMARVPL 106
Cdd:smart00499   1 CGQVLL-QLAPCLSYLVGGSRGAPPSQQCCSQLRGL--NSAQCRClalRAAVLGILEIPGLNAQNAASLPSACGVPPPYT 77


                   ..
gi 1938964377  107 QC 108
Cdd:smart00499  78 DC 79
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
77-189 2.03e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 47.46  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  77 ASGGIPFHIPINPNTTMSLPracnmarvPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKgttafnPMSPTLAPQ 156
Cdd:PRK14971  369 ASGGRGPKQHIKPVFTQPAA--------APQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPP------TVSVDPPAA 434

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1938964377 157 ADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVG 189
Cdd:PRK14971  435 VPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLG 467
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 110-180 4.44e-05

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 43.35  E-value: 4.44e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAfnPMSPTlaPQADVIPTVTPPSPSATNSGRRQNSN 180
Cdd:TIGR00601  83 KVAPPAATPTSAPTPTPSPPASPASGMSAAPASAVE--EKSPS--EESATATAPESPSTSVPSSGSDAAST 149
MSCRAMM_ClfB NF033845
MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial ...
 110-187 1.97e-04

MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468203 [Multi-domain]  Cd Length: 871  Bit Score: 41.47  E-value: 1.97e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPkgttafnpmSPTLAPQADviPTVTPPSPSATNSGRRQNSNTPSAAPS 187
Cdd:NF033845  540 AVNPKDPTPGPPVDPEPSPEPEPEPTPDPEP---------SPDPDPEPS--PDPDPDSDSDSDSGSDSDSGSDSDSDS 606
Med13_C pfam06333
Mediator complex subunit 13 C-terminal domain; Mediator is a large complex of up to 33 ...
 101-180 2.81e-03

Mediator complex subunit 13 C-terminal domain; Mediator is a large complex of up to 33 proteins that is conserved from plants through fungi to humans - the number and representation of individual subunits varying with species. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Med13 is part of the ancillary kinase module, together with Med12, CDK8 and CycC, which in yeast is implicated in transcriptional repression, though most of this activity is likely attributable to the CDK8 kinase. The large Med12 and Med13 proteins are required for specific developmental processes in Drosophila, zebrafish, and Caenorhabditis elegans but their biochemical functions are not understood. This domain is also identified as an RNaseH domain of the medPIWI PIWI/Argonaute module. medPIWI is the core domain found in the Med13 protein. The medPIWI module in Med13 is predicted to bind double-stranded nucleic acids, triggering the experimentally-observed conformational switch in the CDK8 subcomplex which regulates the Mediator complex.


Pssm-ID: 461879  Cd Length: 322  Bit Score: 37.64  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 101 MARVPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPT-VTPPSPSATNSGRRQNS 179
Cdd:pfam06333 158 FGQQSSSTPVSTPQDSSCTHILVFSPSATGQSTPPSGPNEPANAPTTPTDSSPEPDPDALLIdITDETWGVILSHRLNNS 237


                  .
gi 1938964377 180 N 180
Cdd:pfam06333 238 P 238
 
Name Accession Description Interval E-value
LTP_2 pfam14368
Probable lipid transfer; The members of this family are probably involved in lipid transfer. ...
 10-107 5.43e-15

Probable lipid transfer; The members of this family are probably involved in lipid transfer. The family has several highly conserved cysteines, paired in various ways.


Pssm-ID: 433909  Cd Length: 100  Bit Score: 67.51  E-value: 5.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  10 LSCIIVLAILPINAQIVTSPCTATMLTSFTPCLNFLSNGNGTATPSPGCCNAL*TMMGNGSACLCVIASGGIPFHIPINP 89
Cdd:pfam14368   1 LALALAAQAPAPPPAPAAASCTLSMLSGLSPCLPYLTGTPAATAPSPACCGALKSAVSTDVTCLCALVTAPLPIGFPINV 80

                          90
                  ....*....|....*...
gi 1938964377  90 NTTMSLPRACNMARVPLQ 107
Cdd:pfam14368  81 TRALALPRACGVKTPPSS 98
AAI_LTSS cd00010
AAI_LTSS: Alpha-Amylase Inhibitors (AAI), Lipid Transfer (LT) and Seed Storage (SS) Protein ...
 38-101 1.59e-08

AAI_LTSS: Alpha-Amylase Inhibitors (AAI), Lipid Transfer (LT) and Seed Storage (SS) Protein family; a protein family unique to higher plants that includes cereal-type alpha-amylase inhibitors, lipid transfer proteins, seed storage proteins, and similar proteins. Proteins in this family are known to play important roles, in defending plants from insects and pathogens, lipid transport between intracellular membranes, and nutrient storage. Many proteins of this family have been identified as allergens in humans. These proteins contain a common pattern of eight cysteines that form four disulfide bridges.


Pssm-ID: 237980  Cd Length: 63  Bit Score: 49.35  E-value: 1.59e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1938964377  38 FTPCLNFLSNGNgtATPSPGCCNAL*TMMGNGSACLC-VIASGGIPFHIPINPNTTMSLPRACNM 101
Cdd:cd00010     1 LAPCLSYLTGGA--TAPPSDCCSGLKSVVKSDPKCLCaALNGPGASLLGLKNATRALALPAACGL 63
AAI smart00499
Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain ...
 30-108 9.42e-07

Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family;


Pssm-ID: 214698  Cd Length: 79  Bit Score: 45.06  E-value: 9.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377   30 CTATMLtSFTPCLNFLSNGNGTATPSPGCCNAL*TMmgNGSACLC---VIASGGIPFHIPINPNTTMSLPRACNMARVPL 106
Cdd:smart00499   1 CGQVLL-QLAPCLSYLVGGSRGAPPSQQCCSQLRGL--NSAQCRClalRAAVLGILEIPGLNAQNAASLPSACGVPPPYT 77


                   ..
gi 1938964377  107 QC 108
Cdd:smart00499  78 DC 79
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
77-189 2.03e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 47.46  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  77 ASGGIPFHIPINPNTTMSLPracnmarvPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKgttafnPMSPTLAPQ 156
Cdd:PRK14971  369 ASGGRGPKQHIKPVFTQPAA--------APQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPP------TVSVDPPAA 434

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1938964377 157 ADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVG 189
Cdd:PRK14971  435 VPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLG 467
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 110-180 4.44e-05

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 43.35  E-value: 4.44e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAfnPMSPTlaPQADVIPTVTPPSPSATNSGRRQNSN 180
Cdd:TIGR00601  83 KVAPPAATPTSAPTPTPSPPASPASGMSAAPASAVE--EKSPS--EESATATAPESPSTSVPSSGSDAAST 149
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 89-165 1.25e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 42.18  E-value: 1.25e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938964377   89 PNTTMSLPRACNMARVPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVTP 165
Cdd:PRK12270    43 APTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEVTP 119
PRK12495 PRK12495
hypothetical protein; Provisional
 109-191 1.88e-04

hypothetical protein; Provisional


Pssm-ID: 183558 [Multi-domain]  Cd Length: 226  Bit Score: 41.01  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 109 QASTPPAAAPGPvgtEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADviPTVTPPSPSA-TNSGRRQNSNTPSAAPS 187
Cdd:PRK12495  101 QPAAEAEAADQS---APPEASSTSATDEAATDPPATAAARDGPTPDPTAQ--PATPDERRSPrQRPPVSGEPPTPSTPDA 175


                  ....
gi 1938964377 188 VGYG 191
Cdd:PRK12495  176 HVAG 179
MSCRAMM_ClfB NF033845
MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial ...
 110-187 1.97e-04

MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468203 [Multi-domain]  Cd Length: 871  Bit Score: 41.47  E-value: 1.97e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPkgttafnpmSPTLAPQADviPTVTPPSPSATNSGRRQNSNTPSAAPS 187
Cdd:NF033845  540 AVNPKDPTPGPPVDPEPSPEPEPEPTPDPEP---------SPDPDPEPS--PDPDPDSDSDSDSGSDSDSGSDSDSDS 606
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 113-189 2.31e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 2.31e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938964377 113 PPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPmSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVG 189
Cdd:PRK14951  366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAP-APAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA 441
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
111-186 2.50e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 2.50e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938964377 111 STPPAAAPGPVGTEAPSASPTSAPTPSPS-PKGTTAFNPMSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAP 186
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAaPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAP 448
PRK10856 PRK10856
cytoskeleton protein RodZ;
104-187 2.54e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 40.78  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 104 VPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPS 183
Cdd:PRK10856  162 VPLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQ 241


                  ....
gi 1938964377 184 AAPS 187
Cdd:PRK10856  242 AGVS 245
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 123-192 4.31e-04

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 40.26  E-value: 4.31e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938964377 123 TEAPSASPTSAPTPSPS--PKGTTAfnpmsPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVGYGF 192
Cdd:TIGR00601  84 VAPPAATPTSAPTPTPSppASPASG-----MSAAPASAVEEKSPSEESATATAPESPSTSVPSSGSDAASTL 150
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 109-189 4.32e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 4.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPSV 188
Cdd:PRK07764  412 PAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPA 491


                  .
gi 1938964377 189 G 189
Cdd:PRK07764  492 A 492
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 109-187 5.49e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 5.49e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQAdviPTVTPPSPSATNSGRRQNSNTPSAAPS 187
Cdd:PRK07764  406 PAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP---SPPPAAAPSAQPAPAPAAAPEPTAAPA 481
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 113-200 6.56e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 39.87  E-value: 6.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  113 PPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPSVGYGF 192
Cdd:PRK12270    38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117


                   ....*...
gi 1938964377  193 SPLVLIAA 200
Cdd:PRK12270   118 TPLRGAAA 125
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
46-186 7.45e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 7.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  46 SNGNGTATPSPGCCNAL*TMMGNGSACLCVIASGGIPfhipinPNTTMSLPRACNMARVPLQCQASTPPAAAPGPVGTEA 125
Cdd:PRK12323  366 GQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAP------PAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQA 439

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1938964377 126 PSASPTSAPTPSPSPkgttafnPMSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAP 186
Cdd:PRK12323  440 SARGPGGAPAPAPAP-------AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPAD 493
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 102-204 8.87e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.41  E-value: 8.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 102 ARVPLQCQASTPPAAAPGPvgteAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVT-PPSPSATNSGRRQNSN 180
Cdd:PRK14950  365 APQPAKPTAAAPSPVRPTP----APSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHtPESAPKLTRAAIPVDE 440

                          90       100
                  ....*....|....*....|....
gi 1938964377 181 TPSAAPSVGYGFSPLVLIAAFAFI 204
Cdd:PRK14950  441 KPKYTPPAPPKEEEKALIADGDVL 464
PHA03247 PHA03247
large tegument protein UL36; Provisional
 82-197 1.01e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377   82 PFHIPINPNTTMSLPRACNMARVPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGtTAFNPMSPTLAPQADVIP 161
Cdd:PHA03247  2897 SFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG-AVPQPWLGALVPGRVAVP 2975

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1938964377  162 --TVTPPSPSATNSGRRQNSNTPSAAPSVGYGFSPLVL 197
Cdd:PHA03247  2976 rfRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLAL 3013
PRK10856 PRK10856
cytoskeleton protein RodZ;
87-185 1.14e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 38.85  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  87 INPNTTMSLPRACNMARVPlqcQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPTVTPP 166
Cdd:PRK10856  154 LSQNSGQSVPLDTSTTTDP---ATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPAT 230

                          90
                  ....*....|....*....
gi 1938964377 167 SPSATNSGRRQNSNTPSAA 185
Cdd:PRK10856  231 PDGAAPLPTDQAGVSTPAA 249
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 109-186 1.61e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 38.64  E-value: 1.61e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPtSAPTPSPSPKGTTAFNPMSPTLAPQADVI-PTVTPPSPSATnsgrrQNSNTPSAAP 186
Cdd:PRK14950  357 EALLVPVPAPQPAKPTAAAPSP-VRPTPAPSTRPKAAAAANIPPKEPVRETAtPPPVPPRPVAP-----PVPHTPESAP 429
PRK12495 PRK12495
hypothetical protein; Provisional
 110-179 1.80e-03

hypothetical protein; Provisional


Pssm-ID: 183558 [Multi-domain]  Cd Length: 226  Bit Score: 37.93  E-value: 1.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAP-------TPSPSPKGTTAFNPmsPTLAPQADVIPTVTPPSPS---ATNSGRRQNS 179
Cdd:PRK12495  107 EAADQSAPPEASSTSATDEAATDPPataaardGPTPDPTAQPATPD--ERRSPRQRPPVSGEPPTPStpdAHVAGTLQAA 184
Med13_C pfam06333
Mediator complex subunit 13 C-terminal domain; Mediator is a large complex of up to 33 ...
 101-180 2.81e-03

Mediator complex subunit 13 C-terminal domain; Mediator is a large complex of up to 33 proteins that is conserved from plants through fungi to humans - the number and representation of individual subunits varying with species. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Med13 is part of the ancillary kinase module, together with Med12, CDK8 and CycC, which in yeast is implicated in transcriptional repression, though most of this activity is likely attributable to the CDK8 kinase. The large Med12 and Med13 proteins are required for specific developmental processes in Drosophila, zebrafish, and Caenorhabditis elegans but their biochemical functions are not understood. This domain is also identified as an RNaseH domain of the medPIWI PIWI/Argonaute module. medPIWI is the core domain found in the Med13 protein. The medPIWI module in Med13 is predicted to bind double-stranded nucleic acids, triggering the experimentally-observed conformational switch in the CDK8 subcomplex which regulates the Mediator complex.


Pssm-ID: 461879  Cd Length: 322  Bit Score: 37.64  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 101 MARVPLQCQASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPMSPTLAPQADVIPT-VTPPSPSATNSGRRQNS 179
Cdd:pfam06333 158 FGQQSSSTPVSTPQDSSCTHILVFSPSATGQSTPPSGPNEPANAPTTPTDSSPEPDPDALLIdITDETWGVILSHRLNNS 237


                  .
gi 1938964377 180 N 180
Cdd:pfam06333 238 P 238
PRK05641 PRK05641
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 105-142 3.13e-03

putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235540 [Multi-domain]  Cd Length: 153  Bit Score: 36.76  E-value: 3.13e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1938964377 105 PLQCQASTPpAAAPGPVGTEAPSASPTSAPTPSPSPKG 142
Cdd:PRK05641   47 AVQEQVPTP-APAPAPAVPSAPTPVAPAAPAPAPASAG 83
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 108-189 3.17e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 37.74  E-value: 3.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 108 CQASTPPaaaPGPVGTEApsASPTSAPTPSPSPKGTTAfnpmsPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPS 187
Cdd:PRK14959  393 GAATIPT---PGTQGPQG--TAPAAGMTPSSAAPATPA-----PSAAPSPRVPWDDAPPAPPRSGIPPRPAPRMPEASPV 462


                  ..
gi 1938964377 188 VG 189
Cdd:PRK14959  463 PG 464
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 110-186 3.51e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 37.77  E-value: 3.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNPmsPTLAPQADVIPTVTPPSPSATNSGRrqnsnTPSAAP 186
Cdd:PRK14951  414 PAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPP--AQAAPETVAIPVRVAPEPAVASAAP-----APAAAP 483
Tryp_alpha_amyl pfam00234
Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase ...
 33-101 3.90e-03

Protease inhibitor/seed storage/LTP family; This family is composed of trypsin-alpha amylase inhibitors, seed storage proteins and lipid transfer proteins from plants.


Pssm-ID: 425543  Cd Length: 74  Bit Score: 34.85  E-value: 3.90e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938964377  33 TMLTSFTPCLNFLsnGNGTATPSPGCCNAL*TMMgngSACLCVIASGGIPFHIPINPNTTMSLPRACNM 101
Cdd:pfam00234   3 QVLLCLAPCLGYL--QGGCQVPSQQCCSQLRQLQ---AQCRCTAIRAIVLGIEGINPQAAASLPSMCGV 66
PHA03378 PHA03378
EBNA-3B; Provisional
 82-194 4.66e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 37.35  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  82 PFHIPINPNTTmslpRACNMARVPLQCQASTPPAAAPGPV----GTEAPSASPTSAPTPSPSPKGTtafnpmsPTLAPQA 157
Cdd:PHA03378  669 IGHIPYQPSPT----GANTMLPIQWAPGTMQPPPRAPTPMrppaAPPGRAQRPAAATGRARPPAAA-------PGRARPP 737

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1938964377 158 DVIPTVTPPSPSATNSGRRQNSNTPSAAPSVGYGFSP 194
Cdd:PHA03378  738 AAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAP 774
PHA03247 PHA03247
large tegument protein UL36; Provisional
 102-187 4.67e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 37.61  E-value: 4.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377  102 ARVPLQCQASTPPAAAP---GPVGTEAP-SASPTSAPTPSPSPKGTTAFNPMSPtlapqADVIPTVTPPS---PSATNSG 174
Cdd:PHA03247   378 ASLPTRKRRSARHAATPfarGPGGDDQTrPAAPVPASVPTPAPTPVPASAPPPP-----ATPLPSAEPGSddgPAPPPER 452

                           90
                   ....*....|...
gi 1938964377  175 RRQNSNTPSAAPS 187
Cdd:PHA03247   453 QPPAPATEPAPDD 465
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 110-199 4.93e-03

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 37.38  E-value: 4.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 110 ASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAFNP-------MSPTLAPQADVI--PTVTPPSPSATNSGRRQNSN 180
Cdd:PLN02217  569 TNSTPTGSAASSNTTFSSDSPSTVVAPSTSPPAGHLGSPpatpskiVSPSTSPPASHLgsPSTTPSSPESSIKVASTETA 648

                          90
                  ....*....|....*....
gi 1938964377 181 TPSAAPSVGYGFSPLVLIA 199
Cdd:PLN02217  649 SPESSIKVASTESSVSMVS 667
PHA03247 PHA03247
large tegument protein UL36; Provisional
 96-197 4.98e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 37.61  E-value: 4.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377   96 PRACNMARVPLQCQASTPPAAAPGPVGTEAPSASP--------TSAPTPSPSPKGTTA-FNPMSPTLAPQADVIPTVTPP 166
Cdd:PHA03247  2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPagplppptSAQPTAPPPPPGPPPpSLPLGGSVAPGGDVRRRPPSR 2869

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1938964377  167 SPSATNSGRRQNSNTPSAAPSVGYGFSPLVL 197
Cdd:PHA03247  2870 SPAAKPAAPARPPVRRLARPAVSRSTESFAL 2900
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 112-188 5.40e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 37.00  E-value: 5.40e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1938964377 112 TPPAAAPGPvgteAPSASPTSAPTPSPSPKGTTafnpmSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSAAPSV 188
Cdd:PRK14951  383 RPEAAAPAA----APVAQAAAAPAPAAAPAAAA-----SAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPA 450
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 109-187 6.65e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 36.89  E-value: 6.65e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPTSAPTPSPSPKGTTAfnPMSPTLAPQADViPTVTPPSPSATNSGRRQNSNTPSAAPS 187
Cdd:PRK07764  426 AAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP--SAQPAPAPAAAP-EPTAAPAPAPPAAPAPAAAPAAPAAPA 501
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 109-191 6.95e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 36.84  E-value: 6.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPTSAPTPSPSPkgttafnpmsptlAPQAdvIPTVTPPSPSATNSGRRQNSNTPSAAPSV 188
Cdd:PRK14954  397 PDLPQPDRHPGPAKPEAPGARPAELPSPASAP-------------TPEQ--QPPVARSAPLPPSPQASAPRNVASGKPGV 461


                  ...
gi 1938964377 189 GYG 191
Cdd:PRK14954  462 DLG 464
PHA03247 PHA03247
large tegument protein UL36; Provisional
 86-170 7.83e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 36.84  E-value: 7.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377   86 PINPNTTmSLPRACNMARVPlqcqASTPPAAAPGPVGTEAPSASPT--SAPTPSPSPKGTTAFNPMSPTLAPQADVIPTV 163
Cdd:PHA03247  2757 PARPPTT-AGPPAPAPPAAP----AAGPPRRLTRPAVASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPP 2831


                   ....*..
gi 1938964377  164 TPPSPSA 170
Cdd:PHA03247  2832 TSAQPTA 2838
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 109-198 8.07e-03

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 36.72  E-value: 8.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938964377 109 QASTPPAAAPGPVGTEAPSASPTSAPTP-SPSPKGTTAFNP-MSPTLAPQADVIPTVTPPSPSATNSGRRQNSNTPSaAP 186
Cdd:PRK13729  134 PVPQMPASPPGPEGEPQPGNTPVSFPPQgSVAVPPPTAFYPgNGVTPPPQVTYQSVPVPNRIQRKTFTYNEGKKGPS-LP 212

                          90
                  ....*....|...
gi 1938964377 187 SVGYG-FSPLVLI 198
Cdd:PRK13729  213 YIPSGsFAKAMLI 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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