|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06451 |
PRK06451 |
NADP-dependent isocitrate dehydrogenase; |
1-412 |
0e+00 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 235803 Cd Length: 412 Bit Score: 809.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 1 MQKIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFP 80
Cdd:PRK06451 1 MQKIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGPEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEY 160
Cdd:PRK06451 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPLKNPEKIDLIIFRENTDDLYRGIEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 161 PYDSEQAKKIRDFLRKELGVEVEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEV 240
Cdd:PRK06451 161 PYDSEEAKKIRDFLRKELGVEVEDDTGIGIKLISKFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWAYEV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 241 ATKEFRDYIVTEEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGAN 320
Cdd:PRK06451 241 ALKEFRDYVVTEEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGAN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 321 IGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFMGVRALSTTEY 400
Cdd:PRK06451 321 IGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAADLIDKAIMESIKQKKVTQDLARFMGVRALSTTEY 400
|
410
....*....|..
gi 1935521110 401 TDELIAIIDTLS 412
Cdd:PRK06451 401 TDELISIIDMLS 412
|
|
| Icd |
COG0538 |
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part ... |
7-410 |
0e+00 |
|
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440304 Cd Length: 409 Bit Score: 629.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 7 DGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFPKESEEL 86
Cdd:COG0538 2 EGEKIKVEDGKLKVPDNPIIPFIEGDGIGPEITRAIWKVIDAAVEKAYGGKRDIEWKEVDAGEKARDETGDWLPDETAEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 87 IEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEYPYDSEQ 166
Cdd:COG0538 82 IKEYGVGIKGPLTTPVGGGWRSLNVTIRQILDLYVCRRPVRYFKGVPSPVKHPEKVDIVIFRENTEDIYAGIEWKAGSPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 167 AKKIRDFLRKELGVEV---EDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEVATK 243
Cdd:COG0538 162 ALKLIFFLEDEMGVTVirfPEDSGIGIKPVSDEGTERLVRAAIQYALDNKRKSVTLVHKGNIMKFTEGAFKDWGYEVAEE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 244 EFRDYIVTeEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGD 323
Cdd:COG0538 242 EFGDKFIT-EGPWEKYKGPKPAGKIVYKDRIADDMLQQILLRPGEYDVIATKNLNGDYISDALAAQVGGLGIAPGANIGD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 324 TGG-MFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM-GVRALSTTEYT 401
Cdd:COG0538 321 DGGaEFEATHGTAPKYAGKDSTNPGSLILSGTMMLRHRGWLEAADLIEKAVEKTIESGKVTYDLARLMeGATELSTSEFG 400
|
....*....
gi 1935521110 402 DELIAIIDT 410
Cdd:COG0538 401 DAIIENLDK 409
|
|
| prok_nadp_idh |
TIGR00183 |
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent ... |
3-405 |
0e+00 |
|
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent dehydrogenases, including 3-isopropylmalate dehydrogenase, tartrate dehydrogenase, and the multimeric forms of isocitrate dehydrogenase, share a nucleotide binding domain unrelated to that of lactate dehydrogenase and its homologs. These enzymes dehydrogenate their substates at a H-C-OH site adjacent to a H-C-COOH site; Prokaryotic NADP-dependent isocitrate dehydrogenases resemble their NAD-dependent counterparts and 3-isopropylmalate dehydrogenase (an NAD-dependent enzyme) more closely than they resemble eukaryotic NADP-dependent isocitrate dehydrogenases. [Energy metabolism, TCA cycle]
Pssm-ID: 272948 Cd Length: 416 Bit Score: 510.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 3 KIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTG--NRFP 80
Cdd:TIGR00183 6 KPPAQGEKITYENGKLNVPNNPIIPYIEGDGIGVDVTPAAIKVLDAAVEKAYKGEKKIVWFEVYAGEKAYQLYGqdQWLP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEY 160
Cdd:TIGR00183 86 ADTLDAIKEYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYYKGVPSPVKHPEKVDMVIFRENTEDIYAGIEW 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 161 PYDSEQAKKIRDFLRKELGVE---VEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWS 237
Cdd:TIGR00183 166 AEGSEEAKKLIRFLQNELGVKkirFPEDSGIGIKPISEEGTKRLVRAAIEYAIENDRKSVTLVHKGNIMKFTEGAFRDWG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 238 YEVATKEFRDYIVTEEEVTKNYNgvPPSGK-VIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGML 316
Cdd:TIGR00183 246 YELAKKEFGAECITWGLWDKYKN--PNPGKeIVIKDRIADAFLQQILTRPDEYDVIATMNLNGDYISDALAAQVGGIGIA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 317 GGANIGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM-GVRAL 395
Cdd:TIGR00183 324 PGANIGDEIGIFEATHGTAPKYAGQDKVNPGSIILSGEMMLEHMGWKEAADLIKKAMEKAIASKIVTYDFARLMdGAKEV 403
|
410
....*....|
gi 1935521110 396 STTEYTDELI 405
Cdd:TIGR00183 404 KCSEFAEAII 413
|
|
| Iso_dh |
pfam00180 |
Isocitrate/isopropylmalate dehydrogenase; |
25-404 |
1.76e-101 |
|
Isocitrate/isopropylmalate dehydrogenase;
Pssm-ID: 425507 Cd Length: 346 Bit Score: 304.99 E-value: 1.76e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 25 IILYVEGDGIGHEITHAAMKVInKAVEKAYGSdrEIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLETPIG- 103
Cdd:pfam00180 1 KIAVLPGDGIGPEVMAAALKVL-KAALEKAPL--EFEFEERDVGGAAIDETGEPLPDETLEACKKADAVLLGAVGGPKWd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 104 -KGWKSIN--VAIRLMLDLYANIRPVKYIPGIE--SPIKN-ADKIDLIIFRENTDDLYRGIEYpydseqakkirdfLRKE 177
Cdd:pfam00180 78 pAGVRPENglLALRKELGLFANLRPAKVFPPLGdaSPLKNeVEGVDIVIVRELTGGIYFGIEK-------------GIKG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 178 LGVEVeddtGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGaFREWSYEVATKEFRDyivteeevtk 257
Cdd:pfam00180 145 SGNEV----AVDTKLYSRDEIERIARVAFELARKRGRKKVTSVDKANVLKSSDL-WRKIVTEVAKAEYPD---------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 258 nyngvppsgkVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG-GMFEAIHGTAP 336
Cdd:pfam00180 210 ----------VELEHQLVDNAAMQLVKNPSQFDVIVTPNLFGDILSDEASMLTGSLGLLPSASLGANGfGIFEPVHGSAP 279
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1935521110 337 KYAGKNVANPTGIIKGGELMLRF-MGWDKAAELIDSAIMESIRQKKVTQDLARFMgvRALSTTEYTDEL 404
Cdd:pfam00180 280 DIAGKGIANPIATILSAAMMLRYsLGLEDAADKIEAAVLKVLESGIRTGDLAGSA--TYVSTSEFGEAV 346
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06451 |
PRK06451 |
NADP-dependent isocitrate dehydrogenase; |
1-412 |
0e+00 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 235803 Cd Length: 412 Bit Score: 809.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 1 MQKIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFP 80
Cdd:PRK06451 1 MQKIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGPEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEY 160
Cdd:PRK06451 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPLKNPEKIDLIIFRENTDDLYRGIEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 161 PYDSEQAKKIRDFLRKELGVEVEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEV 240
Cdd:PRK06451 161 PYDSEEAKKIRDFLRKELGVEVEDDTGIGIKLISKFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWAYEV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 241 ATKEFRDYIVTEEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGAN 320
Cdd:PRK06451 241 ALKEFRDYVVTEEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGAN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 321 IGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFMGVRALSTTEY 400
Cdd:PRK06451 321 IGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAADLIDKAIMESIKQKKVTQDLARFMGVRALSTTEY 400
|
410
....*....|..
gi 1935521110 401 TDELIAIIDTLS 412
Cdd:PRK06451 401 TDELISIIDMLS 412
|
|
| Icd |
COG0538 |
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part ... |
7-410 |
0e+00 |
|
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440304 Cd Length: 409 Bit Score: 629.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 7 DGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFPKESEEL 86
Cdd:COG0538 2 EGEKIKVEDGKLKVPDNPIIPFIEGDGIGPEITRAIWKVIDAAVEKAYGGKRDIEWKEVDAGEKARDETGDWLPDETAEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 87 IEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEYPYDSEQ 166
Cdd:COG0538 82 IKEYGVGIKGPLTTPVGGGWRSLNVTIRQILDLYVCRRPVRYFKGVPSPVKHPEKVDIVIFRENTEDIYAGIEWKAGSPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 167 AKKIRDFLRKELGVEV---EDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEVATK 243
Cdd:COG0538 162 ALKLIFFLEDEMGVTVirfPEDSGIGIKPVSDEGTERLVRAAIQYALDNKRKSVTLVHKGNIMKFTEGAFKDWGYEVAEE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 244 EFRDYIVTeEEVTKNYNGVPPSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGD 323
Cdd:COG0538 242 EFGDKFIT-EGPWEKYKGPKPAGKIVYKDRIADDMLQQILLRPGEYDVIATKNLNGDYISDALAAQVGGLGIAPGANIGD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 324 TGG-MFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM-GVRALSTTEYT 401
Cdd:COG0538 321 DGGaEFEATHGTAPKYAGKDSTNPGSLILSGTMMLRHRGWLEAADLIEKAVEKTIESGKVTYDLARLMeGATELSTSEFG 400
|
....*....
gi 1935521110 402 DELIAIIDT 410
Cdd:COG0538 401 DAIIENLDK 409
|
|
| prok_nadp_idh |
TIGR00183 |
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent ... |
3-405 |
0e+00 |
|
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent dehydrogenases, including 3-isopropylmalate dehydrogenase, tartrate dehydrogenase, and the multimeric forms of isocitrate dehydrogenase, share a nucleotide binding domain unrelated to that of lactate dehydrogenase and its homologs. These enzymes dehydrogenate their substates at a H-C-OH site adjacent to a H-C-COOH site; Prokaryotic NADP-dependent isocitrate dehydrogenases resemble their NAD-dependent counterparts and 3-isopropylmalate dehydrogenase (an NAD-dependent enzyme) more closely than they resemble eukaryotic NADP-dependent isocitrate dehydrogenases. [Energy metabolism, TCA cycle]
Pssm-ID: 272948 Cd Length: 416 Bit Score: 510.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 3 KIPEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTG--NRFP 80
Cdd:TIGR00183 6 KPPAQGEKITYENGKLNVPNNPIIPYIEGDGIGVDVTPAAIKVLDAAVEKAYKGEKKIVWFEVYAGEKAYQLYGqdQWLP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 81 KESEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEY 160
Cdd:TIGR00183 86 ADTLDAIKEYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYYKGVPSPVKHPEKVDMVIFRENTEDIYAGIEW 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 161 PYDSEQAKKIRDFLRKELGVE---VEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWS 237
Cdd:TIGR00183 166 AEGSEEAKKLIRFLQNELGVKkirFPEDSGIGIKPISEEGTKRLVRAAIEYAIENDRKSVTLVHKGNIMKFTEGAFRDWG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 238 YEVATKEFRDYIVTEEEVTKNYNgvPPSGK-VIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGML 316
Cdd:TIGR00183 246 YELAKKEFGAECITWGLWDKYKN--PNPGKeIVIKDRIADAFLQQILTRPDEYDVIATMNLNGDYISDALAAQVGGIGIA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 317 GGANIGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM-GVRAL 395
Cdd:TIGR00183 324 PGANIGDEIGIFEATHGTAPKYAGQDKVNPGSIILSGEMMLEHMGWKEAADLIKKAMEKAIASKIVTYDFARLMdGAKEV 403
|
410
....*....|
gi 1935521110 396 STTEYTDELI 405
Cdd:TIGR00183 404 KCSEFAEAII 413
|
|
| PRK07006 |
PRK07006 |
isocitrate dehydrogenase; Reviewed |
5-405 |
7.48e-170 |
|
isocitrate dehydrogenase; Reviewed
Pssm-ID: 180792 Cd Length: 409 Bit Score: 481.48 E-value: 7.48e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 5 PEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNR--FPKE 82
Cdd:PRK07006 1 PAEGEKITVNNGKLNVPNNPIIPFIEGDGIGPDITPAMLKVVDAAVEKAYKGERKISWMEIYAGEKATKVYGEDvwLPEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 83 SEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEYPY 162
Cdd:PRK07006 81 TLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENSEDIYAGIEWKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 163 DSEQAKKIRDFLRKELGVE---VEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYE 239
Cdd:PRK07006 161 GSAEAKKVIKFLQEEMGVKkirFPETSGIGIKPVSEEGTERLVRAAIEYAIDNDRKSVTLVHKGNIMKFTEGAFKDWGYQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 240 VATKEFRDYIVTEEEVTKNYNGVPpSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGA 319
Cdd:PRK07006 241 LAEEEFGDELIDGGPWDKIKNPET-GKEIIVKDSIADAFLQQILLRPAEYDVIATMNLNGDYISDALAAQVGGIGIAPGA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 320 NIGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM-GVRALSTT 398
Cdd:PRK07006 320 NINDGHAIFEATHGTAPKYAGLDKVNPGSVILSAEMMLRHMGWTEAADLIIKSMEKTIASKTVTYDFARLMeGATEVKCS 399
|
....*..
gi 1935521110 399 EYTDELI 405
Cdd:PRK07006 400 EFGDALI 406
|
|
| PRK07362 |
PRK07362 |
NADP-dependent isocitrate dehydrogenase; |
5-405 |
2.30e-145 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 180944 Cd Length: 474 Bit Score: 421.81 E-value: 2.30e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 5 PEDGEVIKFENGKWIVPKKPIILYVEGDGIGHEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTG--NRFPKE 82
Cdd:PRK07362 10 PSTGSKITFKNGKPVVPDNPIIPFIRGDGTGVDIWPATQKVLDAAVAKAYGGERKINWFKVYAGDEACDLYGtyQYLPED 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 83 SEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEYPY 162
Cdd:PRK07362 90 TLEAIREYGVAIKGPLTTPIGGGIRSLNVALRQIFDLYSCVRPCRYYAGTPSPHKNPEKLDVIVYRENTEDIYMGIEWEA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 163 DSEQAKKIRDFLRKEL--------GVEVEDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKK--VTIMHKGNVMKYTEGA 232
Cdd:PRK07362 170 GDEIGDKLIKHLNEEVipaspelgKRQIPLGSGIGIKPVSKTGSQRHIRRAIEHALRLPGDKrhVTLVHKGNIMKYTEGA 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 233 FREWSYEVATKEFRDYIVTEEE------VTKN---------------YNGVPPSGK------------------------ 267
Cdd:PRK07362 250 FRDWGYELATTEFRDECVTEREswilsnKEKNpnisiednarmiepgYDSLTPEKKaaicaevkevldsiwsshgngkwk 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 268 --VIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGGMFEAIHGTAPKYAGKNVAN 345
Cdd:PRK07362 330 ekVLVDDRIADSIFQQIQTRPQEYSILATLNLNGDYISDAAAAIVGGLGMAPGANIGDNAAIFEATHGTAPKHAGLDRIN 409
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1935521110 346 PTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLARFM--GVRALSTTEYTDELI 405
Cdd:PRK07362 410 PGSVILSGVMMLEYLGWQEAADLITKGLSAAIANKQVTYDLARLMepPVDPLSCSEFAEAII 471
|
|
| LeuB |
COG0473 |
Isocitrate/isopropylmalate dehydrogenase [Energy production and conversion, Amino acid ... |
26-408 |
3.35e-111 |
|
Isocitrate/isopropylmalate dehydrogenase [Energy production and conversion, Amino acid transport and metabolism]; Isocitrate/isopropylmalate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440241 Cd Length: 346 Bit Score: 330.05 E-value: 3.35e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 26 ILYVEGDGIGHEITHAAMKVInKAVEKAYGSDreIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLETPI--- 102
Cdd:COG0473 4 IAVLPGDGIGPEVVAAALKVL-EAAAERFGLD--FEFEEADIGGAAYDKTGTPLPDETLEALRKADAILLGAVGGPKwdd 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 103 GKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKN--ADKIDLIIFRENTDDLYRGIEypydseqakkirdflrKELGV 180
Cdd:COG0473 81 GVRPESGLLALRKELDLYANLRPAKLYPGLPSPLKPeiVEGIDLVIVRENTEGLYFGIG----------------GRIGT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 181 EVEDDTGIGIKLISRFKTQRIARMAIKYAIDHkRKKVTIMHKGNVMKYTEGAFREWSYEVAtKEFRDyivteeevtknyn 260
Cdd:COG0473 145 GTGEEVAIDTRVYTRKGIERIARYAFELARKR-RKKVTSVDKANVLKLTSGLWREVVREVA-KEYPD------------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 261 gvppsgkVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG-GMFEAIHGTAPKYA 339
Cdd:COG0473 210 -------VELDHMYVDAAAMQLVRNPEQFDVIVTENLFGDILSDLAAGLTGSLGLAPSANIGDEGkALFEPVHGSAPDIA 282
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1935521110 340 GKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLArfmgvRALSTTEYTDELIAII 408
Cdd:COG0473 283 GKGIANPIATILSAAMMLRHLGEEEAADAIEAAVEKVLAEGVRTPDLG-----GKAGTSEMGDAIIAAL 346
|
|
| Iso_dh |
pfam00180 |
Isocitrate/isopropylmalate dehydrogenase; |
25-404 |
1.76e-101 |
|
Isocitrate/isopropylmalate dehydrogenase;
Pssm-ID: 425507 Cd Length: 346 Bit Score: 304.99 E-value: 1.76e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 25 IILYVEGDGIGHEITHAAMKVInKAVEKAYGSdrEIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLETPIG- 103
Cdd:pfam00180 1 KIAVLPGDGIGPEVMAAALKVL-KAALEKAPL--EFEFEERDVGGAAIDETGEPLPDETLEACKKADAVLLGAVGGPKWd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 104 -KGWKSIN--VAIRLMLDLYANIRPVKYIPGIE--SPIKN-ADKIDLIIFRENTDDLYRGIEYpydseqakkirdfLRKE 177
Cdd:pfam00180 78 pAGVRPENglLALRKELGLFANLRPAKVFPPLGdaSPLKNeVEGVDIVIVRELTGGIYFGIEK-------------GIKG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 178 LGVEVeddtGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGaFREWSYEVATKEFRDyivteeevtk 257
Cdd:pfam00180 145 SGNEV----AVDTKLYSRDEIERIARVAFELARKRGRKKVTSVDKANVLKSSDL-WRKIVTEVAKAEYPD---------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 258 nyngvppsgkVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG-GMFEAIHGTAP 336
Cdd:pfam00180 210 ----------VELEHQLVDNAAMQLVKNPSQFDVIVTPNLFGDILSDEASMLTGSLGLLPSASLGANGfGIFEPVHGSAP 279
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1935521110 337 KYAGKNVANPTGIIKGGELMLRF-MGWDKAAELIDSAIMESIRQKKVTQDLARFMgvRALSTTEYTDEL 404
Cdd:pfam00180 280 DIAGKGIANPIATILSAAMMLRYsLGLEDAADKIEAAVLKVLESGIRTGDLAGSA--TYVSTSEFGEAV 346
|
|
| PRK09222 |
PRK09222 |
NADP-dependent isocitrate dehydrogenase; |
22-406 |
2.70e-85 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 236416 [Multi-domain] Cd Length: 482 Bit Score: 267.91 E-value: 2.70e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 22 KKPI-ILYveGDGIGHEITHAAMKVINKAvekayGSDREIKWVEVlaGDKAEK---LTGnrFPKESEELIEKYRVLLKGP 97
Cdd:PRK09222 4 KTPItVAY--GDGIGPEIMEAVLKILEAA-----GAPLEIETIEI--GEKVYKkgwTSG--ISPSAWESIRRTKVLLKAP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 98 LETPIGKGWKSINVAIRLMLDLYANIRPVK-YIPGIESPiknADKIDLIIFRENTDDLYRGIEYpydsEQAkkirdflrk 176
Cdd:PRK09222 73 ITTPQGGGYKSLNVTLRKTLGLYANVRPCVsYHPFVETK---HPNLDVVIIRENEEDLYAGIEH----RQT--------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 177 elgveveDDTGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFRewsyevatKEFrdyivteEEVT 256
Cdd:PRK09222 137 -------PDVYQCLKLISRPGSEKIIRYAFEYARANGRKKVTCLTKDNIMKLTDGLFH--------KVF-------DEIA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 257 KNYngvpPSgkvIIND-RIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGGMFEAIHGTA 335
Cdd:PRK09222 195 KEY----PD---IEAEhYIVDIGAARLATNPENFDVIVTPNLYGDILSDIAAEISGSVGLAGSANIGEEYAMFEAVHGSA 267
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1935521110 336 PKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDL-ARFMGVRALSTTEYTDELIA 406
Cdd:PRK09222 268 PDIAGKNIANPSGLLNAAVMMLVHIGQFDIAELIENAWLKTLEDGIHTADIyNEGVSKKKVGTKEFAEAVIE 339
|
|
| PRK08997 |
PRK08997 |
isocitrate dehydrogenase; Provisional |
26-406 |
6.63e-79 |
|
isocitrate dehydrogenase; Provisional
Pssm-ID: 181606 Cd Length: 334 Bit Score: 246.94 E-value: 6.63e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 26 ILYVEGDGIGHEITHAAMKVINKAvekayGSDREIKWVEvlAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLETPIGKG 105
Cdd:PRK08997 5 ITVIPGDGIGPSIIDATLKILDKL-----GCDFEYEFAD--AGLTALEKHGELLPQRTLDLIEKNKIALKGPLTTPVGEG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 106 WKSINVAIRLMLDLYANIRPVKYIPGIESpikNADKIDLIIFRENTDDLYRGieypydseqakkirdflrkeLGVEVEDD 185
Cdd:PRK08997 78 FTSINVTLRKKFDLYANVRPVLSFPGTKA---RYDNIDIITVRENTEGMYSG--------------------EGQTVSED 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 186 --TGIGIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEVAtKEFRDyIVTEEevtknyngvp 263
Cdd:PRK08997 135 geTAEATSIITRKGAERIVRFAYELARKEGRKKVTAVHKANIMKSTSGLFLKVAREVA-LRYPD-IEFEE---------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 264 psgkviindRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGGMFEAIHGTAPKYAGKNV 343
Cdd:PRK08997 203 ---------MIVDATCMQLVMNPEQFDVIVTTNLFGDILSDLCAGLVGGLGMAPGANIGRDAAIFEAVHGSAPDIAGKNL 273
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1935521110 344 ANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQK-KVTQDLarfmGVRAlSTTEYTDELIA 406
Cdd:PRK08997 274 ANPTSVILAAIQMLEYLGMPDKAERIRKAIVAVIEAGdRTTRDL----GGTH-GTTDFTQAVID 332
|
|
| PRK14025 |
PRK14025 |
multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; Provisional |
26-405 |
3.60e-72 |
|
multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; Provisional
Pssm-ID: 184462 Cd Length: 330 Bit Score: 229.25 E-value: 3.60e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 26 ILYVEGDGIGHEITHAAMKVINkavekayGSDREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPL-ETPigk 104
Cdd:PRK14025 4 ICVIEGDGIGKEVVPAALHVLE-------ATGLPFEFVYAEAGDEVFEKTGKALPEETIEAAKEADAVLFGAAgETA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 105 gwKSINVAIRLMLDLYANIRPVKYIPGIESPIKNadkIDLIIFRENTDDLYRGIEYpydseqakkirdflrkelgvEVED 184
Cdd:PRK14025 74 --ADVIVKLRRILDTYANVRPVKSYKGVKCLYPD---IDYVIVRENTEGLYKGIEA--------------------EIAD 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 185 DTGIGIKLISRFKTQRIARMAIKYAIDHK----RKKVTIMHKGNVMKYTEGAFREWSYEVAtkefrdyivteeevtKNYN 260
Cdd:PRK14025 129 GVTVATRVITRKASERIFRFAFEMAKRRKkmgkEGKVTCAHKANVLKKTDGLFKKTFYEVA---------------KEYP 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 261 GVPPsgkviiNDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGGMFEAIHGTAPKYAG 340
Cdd:PRK14025 194 DIKA------EDYYVDAMNMYIITRPQTFDVVVTSNLFGDILSDGAAGLVGGLGLAPSANIGDKYGLFEPVHGSAPDIAG 267
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1935521110 341 KNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLArfmgvRALSTTEYTDELI 405
Cdd:PRK14025 268 KGIANPTATILTAVLMLRHLGENEEADKVEKALEEVLALGLTTPDLG-----GNLSTMEMAEEVA 327
|
|
| PLN00118 |
PLN00118 |
isocitrate dehydrogenase (NAD+) |
31-411 |
1.15e-70 |
|
isocitrate dehydrogenase (NAD+)
Pssm-ID: 215062 Cd Length: 372 Bit Score: 227.07 E-value: 1.15e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 31 GDGIGHEITHAAMKVINKAvekaygsDREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLETPIGKGWKSIN 110
Cdd:PLN00118 49 GDGIGPEIAESVKQVFTAA-------GVPIEWEEHYVGTTVDPRTGSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLN 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 111 VAIRLMLDLYANIRPVKYIPGIESpikNADKIDLIIFRENTDDLYRGIEYpydseQAKKirdflrkelGVeVEDdtgigI 190
Cdd:PLN00118 122 LTLRKELGLYANVRPCYSLPGYKT---RYDDVDLVTIRENTEGEYSGLEH-----QVVR---------GV-VES-----L 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 191 KLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEVATKeFRDyIVTEEevtknyngvppsgkVII 270
Cdd:PLN00118 179 KIITRQASLRVAEYAFHYAKTHGRKRVSAIHKANIMKKTDGLFLKCCREVAEK-YPE-IVYEE--------------VII 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 271 ndriaDNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG-GMFEAIHGTAPKYAGKNVANPTGI 349
Cdd:PLN00118 243 -----DNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGENGlALAEAVHGSAPDIAGKNLANPTAL 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1935521110 350 IKGGELMLRFMGWDKAAELIDSAIMESIRQKK-VTQDLarfmGVRAlSTTEYTDeliAIIDTL 411
Cdd:PLN00118 318 LLSAVMMLRHLKLNEQAEQIHNAILNTIAEGKyRTADL----GGSS-TTTDFTK---AICDHL 372
|
|
| PRK00772 |
PRK00772 |
3-isopropylmalate dehydrogenase; Provisional |
31-411 |
1.20e-60 |
|
3-isopropylmalate dehydrogenase; Provisional
Pssm-ID: 234832 Cd Length: 358 Bit Score: 200.33 E-value: 1.20e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 31 GDGIGHEITHAAMKVInKAVEKAYGsdREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPletpIGkGWKSIN 110
Cdd:PRK00772 10 GDGIGPEVMAEAVKVL-DAVAEKFG--FDFEFEEALVGGAAIDAHGVPLPEETLEACRAADAVLLGA----VG-GPKWDN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 111 V-----------AIRLMLDLYANIRPVKYIPGIE--SPIKN--ADKIDLIIFRENTDDLY----RGIEYPYDSEQAkkiR 171
Cdd:PRK00772 82 LppdvrpergllALRKELGLFANLRPAKLYPGLAdaSPLKPeiVAGLDILIVRELTGGIYfgepRGREGLGGEERA---F 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 172 DFLRkelgveveddtgigiklISRFKTQRIARMAIKYAIDhKRKKVTIMHKGNVMKYTegafREWsyevatkefRDyIVT 251
Cdd:PRK00772 159 DTMV-----------------YTREEIERIARVAFELARK-RRKKVTSVDKANVLESS----RLW---------RE-VVT 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 252 EeeVTKNYNGVPpsgkviINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG-GMFEA 330
Cdd:PRK00772 207 E--VAKEYPDVE------LSHMYVDNAAMQLVRNPKQFDVIVTENLFGDILSDEAAMLTGSLGMLPSASLGESGpGLYEP 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 331 IHGTAPKYAGKNVANPTGIIKGGELMLRF-MGWDKAAELIDSAIMESIRQKKVTQDLARFMGvrALSTTEYTDELIAIID 409
Cdd:PRK00772 279 IHGSAPDIAGKGIANPIATILSAAMMLRYsLGLEEAADAIEAAVEKVLAQGYRTADIAEGGG--KVSTSEMGDAILAALA 356
|
..
gi 1935521110 410 TL 411
Cdd:PRK00772 357 EG 358
|
|
| PRK03437 |
PRK03437 |
3-isopropylmalate dehydrogenase; Provisional |
29-406 |
2.12e-55 |
|
3-isopropylmalate dehydrogenase; Provisional
Pssm-ID: 179579 Cd Length: 344 Bit Score: 186.29 E-value: 2.12e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 29 VEGDGIGHEITHAAMKVINKAVEKaygsDREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPL---ETPIGKG 105
Cdd:PRK03437 10 IPGDGIGPEVVAEALKVLDAVAAG----GPGVETTEYDLGARRYLRTGETLPDSVLAELRQHDAILLGAIgdpSVPSGVL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 106 WKSINVAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYRGIEypydseqakkirDFLRK----ELGVE 181
Cdd:PRK03437 86 ERGLLLKLRFALDHYVNLRPSKLYPGVTSPLAGPGDIDFVVVREGTEGPYTGNG------------GALRVgtphEVATE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 182 VEDDTgigiklisRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYtegAFREWS---YEVAtKEFRDyivteeeVTKN 258
Cdd:PRK03437 154 VSVNT--------AFGVERVVRDAFERAQKRPRKHLTLVHKTNVLTF---AGDLWQrtvDEVA-AEYPD-------VTVD 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 259 YNGVPpsgkviindriADNMFqqIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGG---MFEAIHGTA 335
Cdd:PRK03437 215 YQHVD-----------AATIF--MVTDPSRFDVIVTDNLFGDIITDLAAAVTGGIGLAASGNINPTGTnpsMFEPVHGSA 281
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1935521110 336 PKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAimesirqkkVTQDLARFMGvRALSTTEYTDELIA 406
Cdd:PRK03437 282 PDIAGQGIADPTAAILSVALLLDHLGEEDAAARIEAA---------VEADLAERGK-MGRSTAEVGDRIAA 342
|
|
| PLN00123 |
PLN00123 |
isocitrate dehydrogenase (NAD+) |
29-409 |
9.89e-51 |
|
isocitrate dehydrogenase (NAD+)
Pssm-ID: 215065 Cd Length: 360 Bit Score: 174.67 E-value: 9.89e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 29 VEGDGIGHEITHAAMKVInkaveKAYGSDREIKWVEVLAGDKaekltgnRFPKESEELIEKYRVLLKGPLETPIGKGWKS 108
Cdd:PLN00123 36 IPGDGIGPLVTGAVEQVM-----EAMHAPVYFERYEVHGDMK-------KVPEEVLESIRRNKVCLKGGLATPVGGGVSS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 109 INVAIRLMLDLYANIRPVKYIPGIESPIKNadkIDLIIFRENTDDLYRGIEYpydseqakkirdflrkelgvEVEDDTGI 188
Cdd:PLN00123 104 LNVQLRKELDLFASLVNCFNLPGLPTRHEN---VDIVVIRENTEGEYSGLEH--------------------EVVPGVVE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 189 GIKLISRFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWSYEVAtkefrdyivteeevtKNYNGVPpsgkv 268
Cdd:PLN00123 161 SLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVA---------------KKYPGIK----- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 269 iINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTGGMFE--AIHGTA--PKYAGKNVA 344
Cdd:PLN00123 221 -YNEIIVDNCCMQLVSKPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPGGNVGADHAVFEqgASAGNVgnEKLVEQKKA 299
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1935521110 345 NPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKV-TQDLArfmgvrALSTT-EYTDELIAIID 409
Cdd:PLN00123 300 NPVALLLSSAMMLRHLQFPSFADRLETAVKRVIAEGKYrTKDLG------GSSTTqEVVDAVIANLD 360
|
|
| TTC |
TIGR02089 |
tartrate dehydrogenase; Tartrate dehydrogenase catalyzes the oxidation of both meso- and (+) ... |
26-408 |
9.16e-47 |
|
tartrate dehydrogenase; Tartrate dehydrogenase catalyzes the oxidation of both meso- and (+)-tartrate as well as a D-malate. These enzymes are closely related to the 3-isopropylmalate and isohomocitrate dehydrogenases found in TIGR00169 and TIGR02088, respectively. [Energy metabolism, Other]
Pssm-ID: 273963 Cd Length: 352 Bit Score: 163.85 E-value: 9.16e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 26 ILYVEGDGIGHEITHAAMKVINkAVEKAYGsDREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKG----PLETP 101
Cdd:TIGR02089 6 IAAIPGDGIGKEVVAAALQVLE-AAAKRHG-GFSLHFTEFPWSCDYYKEHGKMMPEDGLEKLKKFDAIFLGavgwPALVP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 102 IGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPIKNA--DKIDLIIFRENTDDLYrgieypydSEQAKKIRDFLRKELG 179
Cdd:TIGR02089 84 DHISLWGLLLKIRREFDQYANVRPAKLLPGVTSPLRNCgpGDFDFVVVRENSEGEY--------SGVGGRIHRGTDEEVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 180 VEVeddtgigiKLISRFKTQRIARMAIKYAiDHKRKKVTIMHKGNVMKYTegafrewsyevatKEFRDYIVteEEVTKNY 259
Cdd:TIGR02089 156 TQN--------AIFTRKGVERIMRFAFELA-QKRRKHLTSATKSNGIRHS-------------MPFWDEVF--AEVAAEY 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 260 NGVPPSGKVIindriaDNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANI---GDTGGMFEAIHGTAP 336
Cdd:TIGR02089 212 PDVEWDSYHI------DALAARFVLKPETFDVIVASNLFGDILSDLGAALMGSLGVAPSANInpeGKFPSMFEPVHGSAP 285
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1935521110 337 KYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLarfmGVRAlSTTEYTDELIAII 408
Cdd:TIGR02089 286 DIAGKGIANPIGAIWTAAMMLEHLGEKEAGAKIMDAIERVTAAGILTPDV----GGKA-TTSEVTEAVCNAL 352
|
|
| PRK08194 |
PRK08194 |
tartrate dehydrogenase; Provisional |
22-406 |
2.99e-38 |
|
tartrate dehydrogenase; Provisional
Pssm-ID: 181281 Cd Length: 352 Bit Score: 141.01 E-value: 2.99e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 22 KKPIILYVEGDGIGHEITHAAMKVInKAVEKAYGSdreikwvevlagdkaEKLTGNRFPKESEELIEKYRVLLKGPLETP 101
Cdd:PRK08194 2 KQFKIAVIPGDGVGKEVVPAAVRVL-KAVAEVHGG---------------LKFEFTEFPWSCEYYLEHGEMMPEDGLEQL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 102 -------IGK-GWKSIN----------VAIRLMLDLYANIRPVKYIPGIESPIKNADKIDLIIFRENTDDLYrgieypyd 163
Cdd:PRK08194 66 kqfdaifLGAvGNPKLVpdhislwgllIKIRREFEQVINIRPAKQLRGIKSPLANPKDFDLLVVRENSEGEY-------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 164 SEQAKKIRdflrkelgvEVEDDTGIGIKLISRFKTQRIARMAIKYAiDHKRKKVTIMHKGNVMKYtegafrewsyevaTK 243
Cdd:PRK08194 138 SEVGGRIH---------RGEDEIAIQNAVFTRKGTERAMRYAFELA-AKRRKHVTSATKSNGIVH-------------SM 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 244 EFRDYIVteEEVTKNYNGVPPSGKVIindriaDNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGD 323
Cdd:PRK08194 195 PFWDEVF--QEVGKDYPEIETDSQHI------DALAAFFVTRPEEFDVIVASNLFGDILTDIGAAIMGSIGIAPAANINV 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 324 TG---GMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAAELIDSAIMESIRQKKVTQDLarfmGVRAlSTTEY 400
Cdd:PRK08194 267 NGkypSMFEPVHGSAPDIAGKGIANPIGQIWTAKLMLDHFGEEELGSHLLDVIEDVTEDGIKTPDI----GGRA-TTDEV 341
|
....*.
gi 1935521110 401 TDELIA 406
Cdd:PRK08194 342 TDEIIS 347
|
|
| PLN02329 |
PLN02329 |
3-isopropylmalate dehydrogenase |
20-410 |
1.62e-28 |
|
3-isopropylmalate dehydrogenase
Pssm-ID: 215188 Cd Length: 409 Bit Score: 115.56 E-value: 1.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 20 VPKKPIILYVEGDGIGHEITHAAMKVINKAvekAYGSDREIKWVEVLAGDKAEKLTGNRFPKESEELIEKYRVLLKGPLE 99
Cdd:PLN02329 43 GKKRYNIALLPGDGIGPEVISVAKNVLQKA---GSLEGLEFDFQEMPVGGAALDLVGVPLPEETFTAAKQSDAILLGAIG 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 100 tpiGKGWKSIN---------VAIRLMLDLYANIRPVKYIPGI--ESPIKN--ADKIDLIIFRENTDDLYRGieypydseq 166
Cdd:PLN02329 120 ---GYKWDKNEkhlrpemalFYLRRDLKVFANLRPATVLPQLvdASTLKKevAEGVDMMIVRELTGGIYFG--------- 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 167 akKIRDFLRKELGVEVeddtGIGIKLISRFKTQRIARMAIKYAiDHKRKKVTIMHKGNVMKYTegafrewsyevatkefr 246
Cdd:PLN02329 188 --EPRGITINENGEEV----GVSTEIYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLDAS----------------- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 247 dyIVTEEEVTKNYNGVPpsgKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGANIGDTG- 325
Cdd:PLN02329 244 --ILWRKRVTALASEYP---DVELSHMYVDNAAMQLIRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLGESGp 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935521110 326 GMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRF-MGWDKAAELIDSAIMESIRQKKVTQDLARfMGVRALSTTEYTDEL 404
Cdd:PLN02329 319 GLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYgLGEEKAAKRIEDAVVDALNKGFRTGDIYS-PGNKLVGCKEMGEEV 397
|
....*.
gi 1935521110 405 IAIIDT 410
Cdd:PLN02329 398 LKSVDS 403
|
|
| |
