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Conserved domains on  [gi|1929624265|gb|QPA14944|]
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DUF1425 domain-containing protein [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

YcfL family protein( domain architecture ID 10791071)

YcfL family protein is a DUF1425 domain-containing protein similar to Escherichia coli protein YcfL

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YcfL COG5633
Uncharacterized conserved protein YcfL [Function unknown];
18-125 7.13e-52

Uncharacterized conserved protein YcfL [Function unknown];


:

Pssm-ID: 444360  Cd Length: 128  Bit Score: 159.77  E-value: 7.13e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  18 GCRSHPE--IPVNDEQSLVMESSLLAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERP- 94
Cdd:COG5633    16 GCSSSPTsgIPVNSQQPLVMESSVLAAGISAEKPTLSQVGGLLRAQATLSNKSNKPVTLQYRFYWYDKNGLEIHPEESPw 95

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1929624265  95 RSVTIPAHSAVTLYGSANFLGAHKVRLYLYL 125
Cdd:COG5633    96 RTLTLPGNQTVTIQSVAPNPEAKNYRLYLRL 126
 
Name Accession Description Interval E-value
YcfL COG5633
Uncharacterized conserved protein YcfL [Function unknown];
18-125 7.13e-52

Uncharacterized conserved protein YcfL [Function unknown];


Pssm-ID: 444360  Cd Length: 128  Bit Score: 159.77  E-value: 7.13e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  18 GCRSHPE--IPVNDEQSLVMESSLLAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERP- 94
Cdd:COG5633    16 GCSSSPTsgIPVNSQQPLVMESSVLAAGISAEKPTLSQVGGLLRAQATLSNKSNKPVTLQYRFYWYDKNGLEIHPEESPw 95

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1929624265  95 RSVTIPAHSAVTLYGSANFLGAHKVRLYLYL 125
Cdd:COG5633    96 RTLTLPGNQTVTIQSVAPNPEAKNYRLYLRL 126
DUF1425 pfam07233
Protein of unknown function (DUF1425); This family consists of several hypothetical bacterial ...
 40-124 8.74e-33

Protein of unknown function (DUF1425); This family consists of several hypothetical bacterial proteins of around 125 residues in length. Several members of this family are described as putative lipoproteins and are often known as YcfL. The function of this family is unknown.


Pssm-ID: 429361  Cd Length: 87  Bit Score: 110.00  E-value: 8.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  40 LAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERP-RSVTIPAHSAVTLYGSANFLGAHK 118
Cdd:pfam07233   2 LAAGISVEDPSTRRVGGLLRASVVLSNKSSTDVTLQYRFYWYDADGLEVEPEESPwRSITLHGKETVTLQAVAPNPNATQ 81


                  ....*.
gi 1929624265 119 VRLYLY 124
Cdd:pfam07233  82 FRLYVR 87
DUF1425 cd09030
Putative periplasmic lipoprotein; This bacterial family of proteins contains members described ...
 24-124 6.94e-32

Putative periplasmic lipoprotein; This bacterial family of proteins contains members described as putative lipoproteins, some are also known as YcfL. The function of this family is unknown. Family members have also been annotated as predicted periplasmic lipoproteins (COG5633), and appear to contain an N-terminal membrane lipoprotein lipid attachment side (pfam08139), which is not included in this alignment model.


Pssm-ID: 176923  Cd Length: 101  Bit Score: 108.55  E-value: 6.94e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  24 EIPVNDEQSLVMESSLlAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHP-LERPRSVTIPAH 102
Cdd:cd09030     1 GIAINSQQSVVMDSSL-AAGISVIEPRISRTNGLLEAQATLSNTSSKPLTLQYRFYWYDAQGLEVEPeQEPWQSLTLPGG 79

                          90       100
                  ....*....|....*....|..
gi 1929624265 103 SAVTLYGSANFLGAHKVRLYLY 124
Cdd:cd09030    80 QTVTLQAVAPNPEAKDFRLYLR 101
 
Name Accession Description Interval E-value
YcfL COG5633
Uncharacterized conserved protein YcfL [Function unknown];
18-125 7.13e-52

Uncharacterized conserved protein YcfL [Function unknown];


Pssm-ID: 444360  Cd Length: 128  Bit Score: 159.77  E-value: 7.13e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  18 GCRSHPE--IPVNDEQSLVMESSLLAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERP- 94
Cdd:COG5633    16 GCSSSPTsgIPVNSQQPLVMESSVLAAGISAEKPTLSQVGGLLRAQATLSNKSNKPVTLQYRFYWYDKNGLEIHPEESPw 95

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1929624265  95 RSVTIPAHSAVTLYGSANFLGAHKVRLYLYL 125
Cdd:COG5633    96 RTLTLPGNQTVTIQSVAPNPEAKNYRLYLRL 126
DUF1425 pfam07233
Protein of unknown function (DUF1425); This family consists of several hypothetical bacterial ...
 40-124 8.74e-33

Protein of unknown function (DUF1425); This family consists of several hypothetical bacterial proteins of around 125 residues in length. Several members of this family are described as putative lipoproteins and are often known as YcfL. The function of this family is unknown.


Pssm-ID: 429361  Cd Length: 87  Bit Score: 110.00  E-value: 8.74e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  40 LAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERP-RSVTIPAHSAVTLYGSANFLGAHK 118
Cdd:pfam07233   2 LAAGISVEDPSTRRVGGLLRASVVLSNKSSTDVTLQYRFYWYDADGLEVEPEESPwRSITLHGKETVTLQAVAPNPNATQ 81


                  ....*.
gi 1929624265 119 VRLYLY 124
Cdd:pfam07233  82 FRLYVR 87
DUF1425 cd09030
Putative periplasmic lipoprotein; This bacterial family of proteins contains members described ...
 24-124 6.94e-32

Putative periplasmic lipoprotein; This bacterial family of proteins contains members described as putative lipoproteins, some are also known as YcfL. The function of this family is unknown. Family members have also been annotated as predicted periplasmic lipoproteins (COG5633), and appear to contain an N-terminal membrane lipoprotein lipid attachment side (pfam08139), which is not included in this alignment model.


Pssm-ID: 176923  Cd Length: 101  Bit Score: 108.55  E-value: 6.94e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929624265  24 EIPVNDEQSLVMESSLlAAGISAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHP-LERPRSVTIPAH 102
Cdd:cd09030     1 GIAINSQQSVVMDSSL-AAGISVIEPRISRTNGLLEAQATLSNTSSKPLTLQYRFYWYDAQGLEVEPeQEPWQSLTLPGG 79

                          90       100
                  ....*....|....*....|..
gi 1929624265 103 SAVTLYGSANFLGAHKVRLYLY 124
Cdd:cd09030    80 QTVTLQAVAPNPEAKDFRLYLR 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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