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Conserved domains on  [gi|1913122515|gb|QOE89111|]
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DM10 [Arabidopsis thaliana]

Protein Classification

disease resistance family protein( domain architecture ID 1000118)

disease resistance family protein similar to Nicotiana glutinosa TMV resistance protein N; resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein

Gene Ontology:  GO:0006952

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03210 super family cl33662
Resistant to P. syringae 6; Provisional
 12-1037 0e+00

Resistant to P. syringae 6; Provisional


The actual alignment was detected with superfamily member PLN03210:

Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 826.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   12 TWRYRVFTSFHGPDVRKTFLSHLRKQFSYNGISMFDDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210    10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210    90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210   170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210   249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210   327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLRLKTLAYKSLIQISAE 482
Cdd:PLN03210   407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDISEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210   487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  561 TKSRYDGK--YRMNIPAEIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQDSQLEHLWRGTQSLRNLKNLDLRGST 637
Cdd:PLN03210   566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTLTGCSRLRNIPVIST 717
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  718 HISYLDIPKTTELEYVS---------------ASIALWCRLR-----------SLDMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210   726 NISWLDLDETAIEEFPSnlrlenldelilcemKSEKLWERVQpltplmtmlspSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLYNLVAE------------------------------ 814
Cdd:PLN03210   806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLNLSrtgieevpwwiekfsnlsfldmngcnnlqr 884

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  815 -----------------DCESLESV---------------FSTLHTPRARLKFTNCFKLGGEariAIIRRSEFTGMALLP 862
Cdd:PLN03210   885 vslnisklkhletvdfsDCGALTEAswngspsevamatdnIHSKLPSTVCINFINCFNLDQE---ALLQQQSIFKQLILS 961

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  863 GREVPAEFDHRAKGNSLT-ITLNGNRPSYDYTQYMVCVVISTNQ--------EIKKLSNTLSCHINGYIFPDHKELYIGd 933
Cdd:PLN03210   962 GEEVPSYFTHRTTGASLTnIPLLHISPCQPFFRFRACAVVDSESffiisvsfDIQVCCRFIDRLGNHFDSPYQPHVFSV- 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  934 vsKCRREHLFIFHTSYHLHIDPSGASR------EIVFEFSSKLQDFDIIECGVKIWTAQS--IKREYLVFEDDNDikhdd 1005
Cdd:PLN03210  1041 --TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGIRLSEDDSslNNTLPNVEEADDD----- 1113

                         1130      1140      1150
                   ....*....|....*....|....*....|..
gi 1913122515 1006 htNRVNGPYKASNVDYKSVSRKRPRKPDLKLE 1037
Cdd:PLN03210  1114 --NPVNGSEHWEDCEDSALERESERTKDREMR 1143
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 12-1037 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 826.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   12 TWRYRVFTSFHGPDVRKTFLSHLRKQFSYNGISMFDDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210    10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210    90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210   170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210   249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210   327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLRLKTLAYKSLIQISAE 482
Cdd:PLN03210   407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDISEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210   487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  561 TKSRYDGK--YRMNIPAEIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQDSQLEHLWRGTQSLRNLKNLDLRGST 637
Cdd:PLN03210   566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTLTGCSRLRNIPVIST 717
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  718 HISYLDIPKTTELEYVS---------------ASIALWCRLR-----------SLDMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210   726 NISWLDLDETAIEEFPSnlrlenldelilcemKSEKLWERVQpltplmtmlspSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLYNLVAE------------------------------ 814
Cdd:PLN03210   806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLNLSrtgieevpwwiekfsnlsfldmngcnnlqr 884

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  815 -----------------DCESLESV---------------FSTLHTPRARLKFTNCFKLGGEariAIIRRSEFTGMALLP 862
Cdd:PLN03210   885 vslnisklkhletvdfsDCGALTEAswngspsevamatdnIHSKLPSTVCINFINCFNLDQE---ALLQQQSIFKQLILS 961

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  863 GREVPAEFDHRAKGNSLT-ITLNGNRPSYDYTQYMVCVVISTNQ--------EIKKLSNTLSCHINGYIFPDHKELYIGd 933
Cdd:PLN03210   962 GEEVPSYFTHRTTGASLTnIPLLHISPCQPFFRFRACAVVDSESffiisvsfDIQVCCRFIDRLGNHFDSPYQPHVFSV- 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  934 vsKCRREHLFIFHTSYHLHIDPSGASR------EIVFEFSSKLQDFDIIECGVKIWTAQS--IKREYLVFEDDNDikhdd 1005
Cdd:PLN03210  1041 --TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGIRLSEDDSslNNTLPNVEEADDD----- 1113

                         1130      1140      1150
                   ....*....|....*....|....*....|..
gi 1913122515 1006 htNRVNGPYKASNVDYKSVSRKRPRKPDLKLE 1037
Cdd:PLN03210  1114 --NPVNGSEHWEDCEDSALERESERTKDREMR 1143
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 15-180 2.70e-69

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 228.40  E-value: 2.70e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   15 YRVFTSFHGPDVRKTFLSHLRKQFSYNGISMF-DDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEIL 93
Cdd:pfam01582    1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFiDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   94 KCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIagEHFFNWDNEAKMIEKIARDV 173
Cdd:pfam01582   81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                   ....*..
gi 1913122515  174 SNKLNAT 180
Cdd:pfam01582  159 SNKLNGT 165
TIR smart00255
Toll - interleukin 1 - resistance;
14-151 1.84e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 140.15  E-value: 1.84e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515    14 RYRVFTSFHG-PDVRKTFLSHLRKQFSYNGISMFDDQSIERSQtIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEI 92
Cdd:smart00255    1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGG-DLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913122515    93 LKCR-EDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEET-QKWSKALNDVGNI 151
Cdd:smart00255   80 LENAlEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKeQFWKKALYAVPSK 140
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
623-811 3.26e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.21  E-value: 3.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  623 QSLRNLKNLDLRGSTNLKELpdltnaTNLEDLNLNSCEsLVEIPSSFSHLHKLKNLWMSYCiNLQVIPAhmnlvslervT 702
Cdd:COG4886     93 GDLTNLTELDLSGNEELSNL------TNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNN-QLTDLPE----------P 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  703 LTGCSRLRnipvisthisYLDIpKTTELEYVSASIALWCRLRSLDMSYNEnfmgLTHLPMS------LTQLILRYSDIER 776
Cdd:COG4886    155 LGNLTNLK----------SLDL-SNNQLTDLPEELGNLTNLKELDLSNNQ----ITDLPEPlgnltnLEELDLSGNQLTD 219

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1913122515  777 IPDCIKALHQLFSLDLTGCrRLASLPELpGSLYNL 811
Cdd:COG4886    220 LPEPLANLTNLETLDLSNN-QLTDLPEL-GNLTNL 252
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 608-795 1.10e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  608 LNMQDSQLEHLwRGTQSLRNLKNLDLRGStNLKELPDLTNATNLEDLNL--NSCESLveipSSFSHLHKLKNLWMSY-CI 684
Cdd:cd21340      7 LYLNDKNITKI-DNLSLCKNLKVLYLYDN-KITKIENLEFLTNLTHLYLqnNQIEKI----ENLENLVNLKKLYLGGnRI 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  685 nlqvipahmnlvslERVT-LTGCSRLRNIpvistHISYLDIPKTTELEYVSASI-ALWCRLRSLDMSYN--ENFMGLTHL 760
Cdd:cd21340     81 --------------SVVEgLENLTNLEEL-----HIENQRLPPGEKLTFDPRSLaALSNSLRVLNISGNniDSLEPLAPL 141

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1913122515  761 PmSLTQLILRY---SDIERIPDCIKALHQLFSLDLTGC 795
Cdd:cd21340    142 R-NLEQLDASNnqiSDLEELLDLLSSWPSLRELDLTGN 178
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 12-1037 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 826.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   12 TWRYRVFTSFHGPDVRKTFLSHLRKQFSYNGISMFDDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLE 91
Cdd:PLN03210    10 NWVYDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   92 ILKCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIAGEHFFNWDNEAKMIEKIAR 171
Cdd:PLN03210    90 IVRCKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIAN 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  172 DVSNKLNATISWDFEDMVGIEAHLQKMQSLLHLDYEDGAMiVGIYGPAGIGKTTIARALHSRLSSSFQLTCFME------ 245
Cdd:PLN03210   170 DVLGKLNLTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRM-VGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafisk 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  246 --NIRGSYNSglDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSR 323
Cdd:PLN03210   249 smEIYSSANP--DDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSR 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  324 IIVTTEDQELLEQHDVNKKYHVDFPTREEACKIFCTYAFRRSFAPYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKKEDD 403
Cdd:PLN03210   327 IIVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKED 406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  404 WEGILRRLENSLDRKIDGVLRVGYDHLC-EDDQFLYLLIAFFFNYVDDDHVKAMLVEDNLDVKLRLKTLAYKSLIQISAE 482
Cdd:PLN03210   407 WMDMLPRLRNGLDGKIEKTLRVSYDGLNnKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  483 gNIVMHKLLQRVGREAIQRQ--EPTKRRILIDAREICDVLRYGKGTSNVSGISFDTSDISEVTISDDAFKRLHDLRFLKV 560
Cdd:PLN03210   487 -IVEMHSLLQEMGKEIVRAQsnEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEIDELHIHENAFKGMRNLLFLKF 565

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  561 TKSRYDGK--YRMNIPAEIE-FPCLLRLLHWEAYPSKCLPPTFNPEFLVELNMQDSQLEHLWRGTQSLRNLKNLDLRGST 637
Cdd:PLN03210   566 YTKKWDQKkeVRWHLPEGFDyLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  638 NLKELPDLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTLTGCSRLRNIPVIST 717
Cdd:PLN03210   646 NLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDIST 725

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  718 HISYLDIPKTTELEYVS---------------ASIALWCRLR-----------SLDMSYNENFMGLTHLPMS---LTQL- 767
Cdd:PLN03210   726 NISWLDLDETAIEEFPSnlrlenldelilcemKSEKLWERVQpltplmtmlspSLTRLFLSDIPSLVELPSSiqnLHKLe 805

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  768 ---ILRYSDIERIPDCIKaLHQLFSLDLTGCRRLASLPELPGSLYNLVAE------------------------------ 814
Cdd:PLN03210   806 hleIENCINLETLPTGIN-LESLESLDLSGCSRLRTFPDISTNISDLNLSrtgieevpwwiekfsnlsfldmngcnnlqr 884

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  815 -----------------DCESLESV---------------FSTLHTPRARLKFTNCFKLGGEariAIIRRSEFTGMALLP 862
Cdd:PLN03210   885 vslnisklkhletvdfsDCGALTEAswngspsevamatdnIHSKLPSTVCINFINCFNLDQE---ALLQQQSIFKQLILS 961

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  863 GREVPAEFDHRAKGNSLT-ITLNGNRPSYDYTQYMVCVVISTNQ--------EIKKLSNTLSCHINGYIFPDHKELYIGd 933
Cdd:PLN03210   962 GEEVPSYFTHRTTGASLTnIPLLHISPCQPFFRFRACAVVDSESffiisvsfDIQVCCRFIDRLGNHFDSPYQPHVFSV- 1040

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  934 vsKCRREHLFIFHTSYHLHIDPSGASR------EIVFEFSSKLQDFDIIECGVKIWTAQS--IKREYLVFEDDNDikhdd 1005
Cdd:PLN03210  1041 --TKKGSHLVIFDCCFPLNEDNAPLAElnydhvDIQFRLTNKNSQLKLKGCGIRLSEDDSslNNTLPNVEEADDD----- 1113

                         1130      1140      1150
                   ....*....|....*....|....*....|..
gi 1913122515 1006 htNRVNGPYKASNVDYKSVSRKRPRKPDLKLE 1037
Cdd:PLN03210  1114 --NPVNGSEHWEDCEDSALERESERTKDREMR 1143
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 15-180 2.70e-69

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 228.40  E-value: 2.70e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   15 YRVFTSFHGPDVRKTFLSHLRKQFSYNGISMF-DDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEIL 93
Cdd:pfam01582    1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFiDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   94 KCREDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEETQKWSKALNDVGNIagEHFFNWDNEAKMIEKIARDV 173
Cdd:pfam01582   81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                   ....*..
gi 1913122515  174 SNKLNAT 180
Cdd:pfam01582  159 SNKLNGT 165
TIR smart00255
Toll - interleukin 1 - resistance;
14-151 1.84e-38

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 140.15  E-value: 1.84e-38
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515    14 RYRVFTSFHG-PDVRKTFLSHLRKQFSYNGISMFDDQSIERSQtIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEI 92
Cdd:smart00255    1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGG-DLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913122515    93 LKCR-EDIGQIVMTVFYGVDPSDVRKQTGEFGIAFNKTCEGKTNEET-QKWSKALNDVGNI 151
Cdd:smart00255   80 LENAlEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEKeQFWKKALYAVPSK 140
NB-ARC pfam00931
NB-ARC domain;
191-415 2.28e-20

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 91.67  E-value: 2.28e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  191 IEAHLQKMQSllHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSsfqltcfmenIRGSYN-------SGLDEYGLKLR 263
Cdd:pfam00931    1 REDMVEKVIG--KLSEKDEPGIVGIHGMGGVGKTTLAAQIFNDFDE----------VEGHFDsvawvvvSKTFTISTLQQ 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  264 --LQEQLLSKVLNHDGIRINHLGAIPERLCDQKVLIILDDVDDLQQLEALANETNWFGPGSRIIVTTEDQELLEQH-DVN 340
Cdd:pfam00931   69 tiLQNLGLSEDDWDNKEEGELARKIRRALLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAGRVgGPS 148

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1913122515  341 KKYHVDFPTREEACKIFCTYAFRRSF-APYGFEKLAERVTWLCSNLPLGLRVMGSTLRGKK-EDDWEGILRRLENSL 415
Cdd:pfam00931  149 DPHEVELLEPDEAWELFENKVFPKTLgECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKtVEEWKHVYDVLQSEL 225
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
623-811 3.26e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.21  E-value: 3.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  623 QSLRNLKNLDLRGSTNLKELpdltnaTNLEDLNLNSCEsLVEIPSSFSHLHKLKNLWMSYCiNLQVIPAhmnlvslervT 702
Cdd:COG4886     93 GDLTNLTELDLSGNEELSNL------TNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNN-QLTDLPE----------P 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  703 LTGCSRLRnipvisthisYLDIpKTTELEYVSASIALWCRLRSLDMSYNEnfmgLTHLPMS------LTQLILRYSDIER 776
Cdd:COG4886    155 LGNLTNLK----------SLDL-SNNQLTDLPEELGNLTNLKELDLSNNQ----ITDLPEPlgnltnLEELDLSGNQLTD 219

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1913122515  777 IPDCIKALHQLFSLDLTGCrRLASLPELpGSLYNL 811
Cdd:COG4886    220 LPEPLANLTNLETLDLSNN-QLTDLPEL-GNLTNL 252
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
592-811 1.42e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 67.65  E-value: 1.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  592 PSKCLPPTFNPEFLVELNMQDSQLEHLWRGTQSLRNLKNLDLRGSTNLKELPDLTNATNLEDLNLNSCESLVEIPSSFSH 671
Cdd:COG4886     15 LLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGD 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  672 LHKLKNLWMSYCINLQvipahmNLVSLERVTLTGCsRLRNIPV-IS--THISYLDIPKTtELEYVSASIALWCRLRSLDM 748
Cdd:COG4886     95 LTNLTELDLSGNEELS------NLTNLESLDLSGN-QLTDLPEeLAnlTNLKELDLSNN-QLTDLPEPLGNLTNLKSLDL 166

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1913122515  749 SYNEnfmgLTHLPMS------LTQLILRYSDIERIPDCIKALHQLFSLDLTGCrRLASLPELPGSLYNL 811
Cdd:COG4886    167 SNNQ----LTDLPEElgnltnLKELDLSNNQITDLPEPLGNLTNLEELDLSGN-QLTDLPEPLANLTNL 230
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 17-103 2.67e-08

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 53.09  E-value: 2.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   17 VFTSFHGPDvrKTFLSHLRKQFSYNGIS-MFDDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEILKC 95
Cdd:pfam13676    1 VFISYAGED--RAWAEWLADALEAAGYRvWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78


                   ....*...
gi 1913122515   96 REDIGQIV 103
Cdd:pfam13676   79 PEGRKRLI 86
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
605-740 2.77e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 2.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  605 LVELNMQDSQLEHLWRGTQSLRNLKNLDLRGsTNLKELPDLTNATNLEDLNLNSCEsLVEIPSSfSHLHKLKNLWMSYC- 683
Cdd:COG4886    207 LEELDLSGNQLTDLPEPLANLTNLETLDLSN-NQLTDLPELGNLTNLEELDLSNNQ-LTDLPPL-ANLTNLKTLDLSNNq 283

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  684 ---INLQVIPAHMNLVSLERVTLTGCSRLRNIPVISTHISYLDIPKTTELEYVSASIALW 740
Cdd:COG4886    284 ltdLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 608-795 1.10e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  608 LNMQDSQLEHLwRGTQSLRNLKNLDLRGStNLKELPDLTNATNLEDLNL--NSCESLveipSSFSHLHKLKNLWMSY-CI 684
Cdd:cd21340      7 LYLNDKNITKI-DNLSLCKNLKVLYLYDN-KITKIENLEFLTNLTHLYLqnNQIEKI----ENLENLVNLKKLYLGGnRI 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  685 nlqvipahmnlvslERVT-LTGCSRLRNIpvistHISYLDIPKTTELEYVSASI-ALWCRLRSLDMSYN--ENFMGLTHL 760
Cdd:cd21340     81 --------------SVVEgLENLTNLEEL-----HIENQRLPPGEKLTFDPRSLaALSNSLRVLNISGNniDSLEPLAPL 141

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1913122515  761 PmSLTQLILRY---SDIERIPDCIKALHQLFSLDLTGC 795
Cdd:cd21340    142 R-NLEQLDASNnqiSDLEELLDLLSSWPSLRELDLTGN 178
PLN03194 PLN03194
putative disease resistance protein; Provisional
 17-156 1.13e-05

putative disease resistance protein; Provisional


Pssm-ID: 215626 [Multi-domain]  Cd Length: 187  Bit Score: 47.12  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   17 VFTSFHGPDVRKTFLSHLRKQFSYNGISMF-DDQSIERSQTIVPALTGAIKESRISIVVLSKNYASSRWCLDELLEILKC 95
Cdd:PLN03194    29 VFINHRGIDTKRTIATLLYDHLSRLNLRPFlDNKNMKPGDKLFDKINSAIRNCKVGVAVFSPRYCESYFCLHELALIMES 108

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913122515   96 REDigqiVMTVFYGVDPSDVRkqtgefgIAFNKTCEGktnEETQKWSKALNDVGNIAGEHF 156
Cdd:PLN03194   109 KKR----VIPIFCDVKPSQLR-------VVDNGTCPD---EEIRRFNWALEEAKYTVGLTF 155
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 189-316 6.00e-05

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 44.80  E-value: 6.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  189 VGIEAHLQKMQSLLHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSS---FQLTCFMENI-RGSYNSGLDEYGLKLRL 264
Cdd:pfam13191    3 VGREEELEQLLDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERDggyFLRGKCDENLpYSPLLEALTREGLLRQL 82

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913122515  265 QEQLLSKVLNHDGIRI--------NHLGAIPERLCD-------------QKVLIILDDVD-----DLQQLEALANETN 316
Cdd:pfam13191   83 LDELESSLLEAWRAALlealapvpELPGDLAERLLDlllrlldllargeRPLVLVLDDLQwadeaSLQLLAALLRLLE 160
LRR_3 pfam07725
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ...
 604-623 1.00e-04

Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.


Pssm-ID: 429621 [Multi-domain]  Cd Length: 20  Bit Score: 40.01  E-value: 1.00e-04
                           10        20
                   ....*....|....*....|
gi 1913122515  604 FLVELNMQDSQLEHLWRGTQ 623
Cdd:pfam07725    1 NLVELNMPYSKLEKLWEGVK 20
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 215-335 1.73e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 42.90  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  215 IYGPAGIGKTTIARALHsRLSSSFQLTCFMENIRGSYNSGLDEYGLKLRLQEQLLSKVLNHdgirinhlgaiperlcdQK 294
Cdd:cd00009     24 LYGPPGTGKTTLARAIA-NELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELAEKA-----------------KP 85

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1913122515  295 VLIILDDVDD---------LQQLEALANETNWFGPGSRIIVTTEDQELLE 335
Cdd:cd00009     86 GVLFIDEIDSlsrgaqnalLRVLETLNDLRIDRENVRVIGATNRPLLGDL 135
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 624-804 1.62e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 1.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  624 SLRNLKNLDLRGSTNLKELP-DLTNATNLEDLNLNSCESLVEIPSSFSHLHKLKNLWMSYCiNLQ-VIPAHM-NLVSLER 700
Cdd:PLN00113   162 SFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN-NLSgEIPYEIgGLTSLNH 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  701 VTLTGCSRLRNIPVI---STHISYLDIPKTTELEYVSASIALWCRLRSLDMSYNEnfmglthLPMSLTQLILRYSDIEri 777
Cdd:PLN00113   241 LDLVYNNLTGPIPSSlgnLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNS-------LSGEIPELVIQLQNLE-- 311

                          170       180
                   ....*....|....*....|....*....
gi 1913122515  778 pdcikALHqLFSLDLTGC--RRLASLPEL 804
Cdd:PLN00113   312 -----ILH-LFSNNFTGKipVALTSLPRL 334
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 212-314 1.72e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.05  E-value: 1.72e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515   212 IVGIYGPAGIGKTTIARALHSRLSSSfqltcfmeNIRGSYNSGLDEYGLKLRLQEQLLSKVLNHDGIRINHLGAIPERLC 291
Cdd:smart00382    4 VILIVGPPGSGKTTLARALARELGPP--------GGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALAR 75

                            90       100
                    ....*....|....*....|....
gi 1913122515   292 DQKV-LIILDDVDDLQQLEALANE 314
Cdd:smart00382   76 KLKPdVLILDEITSLLDAEQEALL 99
ATPase_2 pfam01637
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ...
 199-308 1.83e-03

ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.


Pssm-ID: 376582 [Multi-domain]  Cd Length: 222  Bit Score: 41.15  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  199 QSLLHLDYEDGAMIVGIYGPAGIGKTTIARALHSRLSSSFQLTCFMENIRGSYNSGLDEYGLKLRLQEQLLSKVLNHDGI 278
Cdd:pfam01637    9 KELEEWAERGPNLIYVIYGPEGCGKTALLRESIENLLDLGYYVIYYDPLRRYFISKLDRFEEVRRLAEALGIAVPKAELE 88

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1913122515  279 RINH--------LGAIPERLcdQKVLIIlddVDDLQQL 308
Cdd:pfam01637   89 ESKLaflaiellLEALKRRG--KKIAII---IDEVQQA 121
AAA_18 pfam13238
AAA domain;
213-335 2.14e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 39.33  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  213 VGIYGPAGIGKTTIARALHSRLSSSFQLTCFMENiRGSYNSGLDEYGLKLRLQEQLLSKVLNhdgiriNHLGAIPERLCD 292
Cdd:pfam13238    1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALE-NGLVLGDDPETRESKRLDEDKLDRLLD------LLEENAALEEGG 73

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1913122515  293 qkvLIILDDVDDLQQLEalanetnWFGPGSRIIVTTEDQELLE 335
Cdd:pfam13238   74 ---NLIIDGHLAELEPE-------RAKDLVGIVLRASPEELLE 106
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
 201-316 2.27e-03

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 40.93  E-value: 2.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  201 LLHLDY--EDGAMIVGIYGPAGIGKTTIARALHSRLSSSFQLTCFmenirgsYNSGLDEyglklrlqEQLLSKVLNHDGI 278
Cdd:COG3267     32 LARLEYalAQGGGFVVLTGEVGTGKTTLLRRLLERLPDDVKVAYI-------PNPQLSP--------AELLRAIADELGL 96

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1913122515  279 RINH------LGAIPERLCDQ-----KVLIILDD-----VDDLQQLEALAN-ETN 316
Cdd:COG3267     97 EPKGaskadlLRQLQEFLLELaaagrRVVLIIDEaqnlpPETLEELRLLSNlETD 151
C-JID pfam20160
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ...
 861-980 2.68e-03

C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.


Pssm-ID: 466313  Cd Length: 108  Bit Score: 38.58  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  861 LPGREVPAEFDHRAKGNSLTITLngnrPSYDYTQYM----VCVVIStnqeikkLSNTLSCHInGYIFPDHKELY-IGDVS 935
Cdd:pfam20160    1 LPGSQIPEWFNHQSTGSSISIKL----PENWYNDNFlgfaVCAVGS-------LIPSLHNFL-GYIHFFLIPLVsLWDTS 68

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1913122515  936 KCRrehlFIFHTSYHLhidpsgasreIVFEFSSKLQDFDIIECGV 980
Cdd:pfam20160   69 KAN----GKTPNDYGR----------IEASFEFPSDLHEIKQCGV 99
NACHT pfam05729
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ...
 215-336 3.02e-03

NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.


Pssm-ID: 428606 [Multi-domain]  Cd Length: 166  Bit Score: 39.60  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  215 IYGPAGIGKTTIARALHS-----RLSSSFQLTCFMEnirgsyNSGLDEYGLKLRLQEQLLSKVLNHDG-IR--INHLGAI 286
Cdd:pfam05729    5 LQGEAGSGKTTLLQKLALlwaqgKLPQGFDFVFFLP------CRELSRSGNARSLADLLFSQWPEPAApVSevWAVILEL 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913122515  287 PERlcdqkVLIILDDVD----DLQQLEALANETNWFG--------PGSRIIVTT------EDQELLEQ 336
Cdd:pfam05729   79 PER-----LLLILDGLDelvsDLGQLDGPCPVLTLLSsllrkkllPGASLLLTVrpdalrDLRRGLEE 141
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 597-811 8.12e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 8.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  597 PPTFNPEFLVELNMQDSQL-----EHLWRGTQSLR--NLKNLDLRGSTNLKELPdltnatNLEDLNLNSCESLVEIPSSF 669
Cdd:PLN00113    87 SAIFRLPYIQTINLSNNQLsgpipDDIFTTSSSLRylNLSNNNFTGSIPRGSIP------NLETLDLSNNMLSGEIPNDI 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  670 SHLHKLKNLWMSYCINLQVIPAHM-NLVSLERVTLTGCSRLRNIPVISTHISYLdipKTTELEYVSAS------IALWCR 742
Cdd:PLN00113   161 GSFSSLKVLDLGGNVLVGKIPNSLtNLTSLEFLTLASNQLVGQIPRELGQMKSL---KWIYLGYNNLSgeipyeIGGLTS 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913122515  743 LRSLDMSYNeNFMGltHLPMSLTQLilrySDIE-----------RIPDCIKALHQLFSLDLTGCRRLASLPELPGSLYNL 811
Cdd:PLN00113   238 LNHLDLVYN-NLTG--PIPSSLGNL----KNLQylflyqnklsgPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNL 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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