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Conserved domains on  [gi|1607460592|gb|QBU42408|]
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SPOR domain-containing protein [Bordetella pertussis]

Protein Classification

SPOR domain-containing protein( domain architecture ID 10523510)

SPOR domain-containing protein similar to Pseudomonas aeruginosa endolytic peptidoglycan transglycosylase RlpA

CATH:  3.30.70.1070
Gene Ontology:  GO:0042834
PubMed:  28396350|26305949
SCOP:  4002705

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 198-273 2.10e-12

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


:

Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 61.22  E-value: 2.10e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1607460592 198 ANGNFVLQVASYTTQADAQARRGKLHQAGVTNAFVeqASINGKQQYRLRVGPFPSREAAQAAQARLRTLGYDNGFI 273
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAEALAAKLRAKGFAAYVA--VTSKGGGLYRVRVGPFASREEARAALKKLKALAGLSPFV 74
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
86-276 7.55e-10

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 57.33  E-value: 7.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592  86 PQAAAPQPEQPAPQAPAGTPEAGAPQPPALASAPPQTPPPGQTPAQPQTPPAAQPPATPPQQAATPPAAPKPEAKPEPKP 165
Cdd:COG3087     9 LLAAAALLLELSAEAAAAASDNLRLAAGSAAAPALAEDALVASAAKAGLAETGAKAGAILAAAALAALNAAAAALAAASA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 166 AKPAAPARSDDGARAMALLEGRSPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVtNAFVEQASINGKQQYRL 245
Cdd:COG3087    89 AAAAAAAPAAAAAEAAAAPAGMAKKEAAAAPAAKKPYYVQVGAFRSRANAERLRARLALLGL-EARVVEVEVGGGTWYRV 167

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1607460592 246 RVGPFPSREAAQAAQARLRTLGYDNGFIAAQ 276
Cdd:COG3087   168 RVGPFSSRAEAEKAREKLKAAGIDALVVRVK 198
 
Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 198-273 2.10e-12

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 61.22  E-value: 2.10e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1607460592 198 ANGNFVLQVASYTTQADAQARRGKLHQAGVTNAFVeqASINGKQQYRLRVGPFPSREAAQAAQARLRTLGYDNGFI 273
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAEALAAKLRAKGFAAYVA--VTSKGGGLYRVRVGPFASREEARAALKKLKALAGLSPFV 74
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 188-276 5.17e-10

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 56.32  E-value: 5.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 188 SPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVtNAFVEQASINGKQQYRLRVGPFPSREAAQAAQARLRTLG 267
Cdd:COG3147    52 AAPAAKAAAPAGGGWVVQLGAFSNEDNAKELVAKLRAAGY-PAYTEPVTTGGGTLYRVRVGPFASRAEAEAALAKLKKLT 130


                  ....*....
gi 1607460592 268 YDNGFIAAQ 276
Cdd:COG3147   131 GLKGFVVRY 139
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
86-276 7.55e-10

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 57.33  E-value: 7.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592  86 PQAAAPQPEQPAPQAPAGTPEAGAPQPPALASAPPQTPPPGQTPAQPQTPPAAQPPATPPQQAATPPAAPKPEAKPEPKP 165
Cdd:COG3087     9 LLAAAALLLELSAEAAAAASDNLRLAAGSAAAPALAEDALVASAAKAGLAETGAKAGAILAAAALAALNAAAAALAAASA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 166 AKPAAPARSDDGARAMALLEGRSPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVtNAFVEQASINGKQQYRL 245
Cdd:COG3087    89 AAAAAAAPAAAAAEAAAAPAGMAKKEAAAAPAAKKPYYVQVGAFRSRANAERLRARLALLGL-EARVVEVEVGGGTWYRV 167

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1607460592 246 RVGPFPSREAAQAAQARLRTLGYDNGFIAAQ 276
Cdd:COG3087   168 RVGPFSSRAEAEKAREKLKAAGIDALVVRVK 198
PRK10672 PRK10672
endolytic peptidoglycan transglycosylase RlpA;
188-276 7.86e-04

endolytic peptidoglycan transglycosylase RlpA;


Pssm-ID: 236733 [Multi-domain]  Cd Length: 361  Bit Score: 40.43  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 188 SPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVTNAFVEQASingkQQYRLRVGPFPSREAAQAAQARLRTLG 267
Cdd:PRK10672  276 APQAAATSSSASGNFVVQVGAVSDQQRAQQWQQSLSQRFGVPGRVTQNG----AVYRVQLGPFASRQQASALQQRLQTEA 351


                  ....*....
gi 1607460592 268 YDNGFIAAQ 276
Cdd:PRK10672  352 QQQSFITTA 360
 
Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 198-273 2.10e-12

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 61.22  E-value: 2.10e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1607460592 198 ANGNFVLQVASYTTQADAQARRGKLHQAGVTNAFVeqASINGKQQYRLRVGPFPSREAAQAAQARLRTLGYDNGFI 273
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAEALAAKLRAKGFAAYVA--VTSKGGGLYRVRVGPFASREEARAALKKLKALAGLSPFV 74
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 188-276 5.17e-10

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 56.32  E-value: 5.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 188 SPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVtNAFVEQASINGKQQYRLRVGPFPSREAAQAAQARLRTLG 267
Cdd:COG3147    52 AAPAAKAAAPAGGGWVVQLGAFSNEDNAKELVAKLRAAGY-PAYTEPVTTGGGTLYRVRVGPFASRAEAEAALAKLKKLT 130


                  ....*....
gi 1607460592 268 YDNGFIAAQ 276
Cdd:COG3147   131 GLKGFVVRY 139
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
86-276 7.55e-10

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 57.33  E-value: 7.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592  86 PQAAAPQPEQPAPQAPAGTPEAGAPQPPALASAPPQTPPPGQTPAQPQTPPAAQPPATPPQQAATPPAAPKPEAKPEPKP 165
Cdd:COG3087     9 LLAAAALLLELSAEAAAAASDNLRLAAGSAAAPALAEDALVASAAKAGLAETGAKAGAILAAAALAALNAAAAALAAASA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 166 AKPAAPARSDDGARAMALLEGRSPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVtNAFVEQASINGKQQYRL 245
Cdd:COG3087    89 AAAAAAAPAAAAAEAAAAPAGMAKKEAAAAPAAKKPYYVQVGAFRSRANAERLRARLALLGL-EARVVEVEVGGGTWYRV 167

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1607460592 246 RVGPFPSREAAQAAQARLRTLGYDNGFIAAQ 276
Cdd:COG3087   168 RVGPFSSRAEAEKAREKLKAAGIDALVVRVK 198
PRK10672 PRK10672
endolytic peptidoglycan transglycosylase RlpA;
188-276 7.86e-04

endolytic peptidoglycan transglycosylase RlpA;


Pssm-ID: 236733 [Multi-domain]  Cd Length: 361  Bit Score: 40.43  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1607460592 188 SPPPAQSKPAANGNFVLQVASYTTQADAQARRGKLHQAGVTNAFVEQASingkQQYRLRVGPFPSREAAQAAQARLRTLG 267
Cdd:PRK10672  276 APQAAATSSSASGNFVVQVGAVSDQQRAQQWQQSLSQRFGVPGRVTQNG----AVYRVQLGPFASRQQASALQQRLQTEA 351


                  ....*....
gi 1607460592 268 YDNGFIAAQ 276
Cdd:PRK10672  352 QQQSFITTA 360
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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