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Conserved domains on  [gi|1605131495|gb|QBR55182|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Lagenorhynchus obliquidens]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 2.08e-79

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 233.54  E-value: 2.08e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   1 MAMYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  81 EVWVSNKVVLGGFLLGLVLELLVVLYVLEGGKVNIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1605131495 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 2.08e-79

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 233.54  E-value: 2.08e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   1 MAMYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  81 EVWVSNKVVLGGFLLGLVLELLVVLYVLEGGKVNIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1605131495 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 3.08e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  18 VGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLGGFLLGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1605131495  98 VLELLvvlyvleggkvnIVFEFNGLGDWVIYDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLFIGVVVIMEI 171
Cdd:pfam00499  81 LLLAL------------LLLVLLSASLTPAAAAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 2.08e-79

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 233.54  E-value: 2.08e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   1 MAMYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109    1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  81 EVWVSNKVVLGGFLLGLVLELLVVLYVLEGGKVNIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109   81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                         170
                  ....*....|....*
gi 1605131495 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109  161 LFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-174 2.09e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 111.39  E-value: 2.09e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   3 MYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEV 82
Cdd:MTH00138    2 TYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPES 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  83 WVSNKVVLGGFLLGLVLELLVVLYVLEGGKvnivfefnglGDWVI-YDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00138   82 WGSWSVLGYVVGYLVGVVLAAGLFWGGWYE----------GSWVVvDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVL 151

                         170
                  ....*....|...
gi 1605131495 162 FIGVVVIMEITRG 174
Cdd:MTH00138  152 LLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 3-174 4.52e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 102.62  E-value: 4.52e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   3 MYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEV 82
Cdd:MTH00065    2 MYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  83 WVSnkvvlGGFLLGLVLELLVVLYVLEGGKVNIVFEFnglgdWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLF 162
Cdd:MTH00065   82 WGS-----WSVLVYVLFYLLLLIVGYILFGCNFSLEF-----LFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLL 151

                         170
                  ....*....|..
gi 1605131495 163 IGVVVIMEITRG 174
Cdd:MTH00065  152 LTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 3-174 1.25e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 93.66  E-value: 1.25e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   3 MYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEV 82
Cdd:MTH00115    2 MYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  83 WVSNKVVLGGFLLGLVLELLVVLYVLeggkvniVFEFNGLGDWVIyDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLF 162
Cdd:MTH00115   82 WGDWGVVGYVVGFVLVVVVVGVVVGG-------LWGMEGVGVVTV-DSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLL 153

                         170
                  ....*....|..
gi 1605131495 163 IGVVVIMEITRG 174
Cdd:MTH00115  154 LTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 3-174 2.62e-17

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 74.64  E-value: 2.62e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   3 MYIVFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEV 82
Cdd:MTH00214    2 LYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPES 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  83 WVSNKVVLGGFLLGLVLEllvvlyvleggkvnIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLF 162
Cdd:MTH00214   82 WGGWSVLLFFLFYLLGLG--------------FVGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLF 147

                         170
                  ....*....|..
gi 1605131495 163 IGVVVIMEITRG 174
Cdd:MTH00214  148 LVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 3-175 7.19e-13

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 63.00  E-value: 7.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   3 MYIVFIMSTIFVISLVGVSSkpSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEV 82
Cdd:MTH00045    2 VFYLFLILMLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  83 WVSNKVVLGGFLLGLVlellvvlyvleggkvnIVFEFNGLGDWVIYDTGDSGFFSEeaMGIAALYSYGTWLVIVTGWSLF 162
Cdd:MTH00045   80 SNLGEVLVLSLLLSLW----------------VFISFDNFLELSNNNWSLVSLSDL--VGSSELYNSGGLYLLLGGFILL 141

                         170
                  ....*....|...
gi 1605131495 163 IGVVVIMEITRGN 175
Cdd:MTH00045  142 VALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 3.08e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495  18 VGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLGGFLLGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1605131495  98 VLELLvvlyvleggkvnIVFEFNGLGDWVIYDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLFIGVVVIMEI 171
Cdd:pfam00499  81 LLLAL------------LLLVLLSASLTPAAAAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 1-78 4.96e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 38.68  E-value: 4.96e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1605131495   1 MAMYIVFIMSTIFVISLVgvsskPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQ 78
Cdd:MTH00015    3 LSFFLILMISLTCSLFLA-----TTPITLGINILMMALLLATTMASALSSWFAFLTFLIYVGGMLVMFAYFLALTPNQ 75
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 6-75 6.78e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 38.33  E-value: 6.78e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1605131495   6 VFIMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMA 75
Cdd:MTH00152    3 LMILLSVCFSLFLLLPLSKQPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 8-75 4.52e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 35.75  E-value: 4.52e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1605131495   8 IMSTIFVISLVGVSSKPSPIYGGLGLIVGGAMGCGIVYSFGGSFLGLMVFLIYLGGMLVVFGYTTAMA 75
Cdd:MTH00212    5 LLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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