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Conserved domains on  [gi|1566441680|gb|QAZ75131|]
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RelB/StbD replicon stabilization protein (plasmid) [Escherichia coli]

Protein Classification

type II toxin-antitoxin system Phd/YefM family antitoxin( domain architecture ID 10005482)

type II toxin-antitoxin (TA) system Phd/YefM family antitoxin is the antitoxin component of a TA module that binds to its cognate toxin and neutralizes its mRNA interferase activity; similar to Escherichia virus P1 antitoxin phd (prevent-host-death)

Gene Ontology:  GO:0003677|GO:0097351|GO:0006355|GO:0045927|GO:0110001
PubMed:  9829946|18757857|27159580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-83 1.26e-13

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


:

Pssm-ID: 441764  Cd Length: 83  Bit Score: 59.80  E-value: 1.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566441680  9 TAASITDLKKNPMGTV--AEGEGDAVAILNRNEPAFYCVPPELYAYYRE---LAEDAELNAIADERMKNPDIVRVNLDDL 83
Cdd:COG2161    2 TTISYSEARKNLASLLdqVVEDHEPVIITRRNGPAAVLISAEDYESLQEtlyLLSSPANAERLLESLAELEAGEVSLDEL 81
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-83 1.26e-13

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 59.80  E-value: 1.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566441680  9 TAASITDLKKNPMGTV--AEGEGDAVAILNRNEPAFYCVPPELYAYYRE---LAEDAELNAIADERMKNPDIVRVNLDDL 83
Cdd:COG2161    2 TTISYSEARKNLASLLdqVVEDHEPVIITRRNGPAAVLISAEDYESLQEtlyLLSSPANAERLLESLAELEAGEVSLDEL 81
PRK02854 PRK02854
primosomal protein DnaT;
1-58 1.08e-08

primosomal protein DnaT;


Pssm-ID: 179484  Cd Length: 179  Bit Score: 49.03  E-value: 1.08e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1566441680   1 MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAE 58
Cdd:PRK02854    1 MSSRILTSDVIGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEE 58
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-83 1.26e-13

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 59.80  E-value: 1.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566441680  9 TAASITDLKKNPMGTV--AEGEGDAVAILNRNEPAFYCVPPELYAYYRE---LAEDAELNAIADERMKNPDIVRVNLDDL 83
Cdd:COG2161    2 TTISYSEARKNLASLLdqVVEDHEPVIITRRNGPAAVLISAEDYESLQEtlyLLSSPANAERLLESLAELEAGEVSLDEL 81
PRK02854 PRK02854
primosomal protein DnaT;
1-58 1.08e-08

primosomal protein DnaT;


Pssm-ID: 179484  Cd Length: 179  Bit Score: 49.03  E-value: 1.08e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1566441680   1 MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAE 58
Cdd:PRK02854    1 MSSRILTSDVIGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEE 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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