|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03226 |
PLN03226 |
serine hydroxymethyltransferase; Provisional |
1-468 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 215639 Cd Length: 475 Bit Score: 977.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 1 MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIES 80
Cdd:PLN03226 4 MVSVPKWGNAPLEEVDPEIADIIEKEKRRQWKGLELIASENFTSRAVMEALGSCLTNKYSEGLPGARYYGGNEYIDQIET 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 81 LCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKnISATSIYFENLPYK 160
Cdd:PLN03226 84 LCQKRALEAFRLDPEKWGVNVQPLSGSPANFAVYTALLQPHDRIMGLDLPHGGHLSHGYQTDGKK-ISATSIYFESMPYR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 161 VDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTT 240
Cdd:PLN03226 163 LDESTGLIDYDKLEKKAMLFRPKLIIAGASAYPRDWDYARMRKIADKVGALLMCDMAHISGLVAAQEAASPFEYCDVVTT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 241 STHKSLRGPRAGMIFYRKGPKPAKKGQpEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKA 320
Cdd:PLN03226 243 TTHKSLRGPRGGMIFFRKGPKPPKGQG-EGAVYDYEDKINFAVFPGLQGGPHNHTIAALAVALKQAMTPEFKAYQKQVKA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 321 NAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGL 400
Cdd:PLN03226 322 NAAALANRLMSKGYKLVTGGTDNHLVLWDLRPLGLTGSRVEKVLDLAHITLNKNAVPGDSSALVPGGVRIGTPAMTSRGL 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75337724 401 VEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNN---KEIDEIKADVEEFTYDFDMPGFFISESR 468
Cdd:PLN03226 402 VEKDFEKVAEFLHRAVTIALKIQKEHGKKLKDFKKGLESNdfsKDIEALRAEVEEFATSFPMPGFDKESMK 472
|
|
| SHMT |
pfam00464 |
Serine hydroxymethyltransferase; |
12-412 |
0e+00 |
|
Serine hydroxymethyltransferase;
Pssm-ID: 395372 Cd Length: 399 Bit Score: 652.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 12 LDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFH 91
Cdd:pfam00464 1 LEDSDPEVFDIIKKEKERQREGIELIASENFTSRAVMEALGSVLTNKYSEGYPGKRYYGGCEHVDEIETLCQDRALEAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 92 CNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSgGKNISATSIYFENLPYKVDSKTGYIDYD 171
Cdd:pfam00464 81 LDPAKWGVNVQPLSGSPANLAVYTALLEPGDRIMGLDLPHGGHLTHGYPVN-SKKISASSKFFESMPYGVDPETGYIDYD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 172 KLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRA 251
Cdd:pfam00464 160 QLEKNAKLFRPKLIVAGTSAYSRLIDYARFREIADEVGAYLMVDMAHISGLVAAGVIPSPFPYADVVTTTTHKTLRGPRG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 252 GMIFYRKGPKPAKKGQPEGeVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLIN 331
Cdd:pfam00464 240 GMIFYRKGVKSVDKTGKEI-LYELEKKINSAVFPGLQGGPHNHVIAAKAVALKQALTPEFKEYQQQVVKNAKALAEALTE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 332 KGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEF 411
Cdd:pfam00464 319 RGYKLVSGGTDNHLVLVDLRPKGLDGARAEKVLEAANITANKNTIPGDKSAFVPSGLRLGTPALTSRGFGEADFEKVAGF 398
|
.
gi 75337724 412 L 412
Cdd:pfam00464 399 I 399
|
|
| SHMT |
cd00378 |
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate ... |
15-453 |
0e+00 |
|
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl group of N5, N10-methylene tetrahydrofolate to glycine resulting in the formation of serine and tetrahydrofolate. Both eukaryotic and prokaryotic SHMT enzymes form tight obligate homodimers; the mammalian enzyme forms a homotetramer comprising four pyridoxal phosphate-bound active sites.
Pssm-ID: 99733 Cd Length: 402 Bit Score: 590.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 15 VDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNp 94
Cdd:cd00378 3 VDPEIAEIIKKENERQRETLELIASENFTSPAVMEAMGSDLTNKYAEGYPGKRYYGGCEYVDEIEDLAIERAKKLFGAE- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 95 ekwGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSggknISATSIYFENLPYKVDSKTGYIDYDKLE 174
Cdd:cd00378 82 ---YANVQPHSGSQANLAVYFALLEPGDTIMGLDLSHGGHLTHGSFTK----VSASGKLFESVPYGVDPETGLIDYDALE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 175 EKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMI 254
Cdd:cd00378 155 KMALEFKPKLIVAGASAYPRPIDFKRFREIADEVGAYLLVDMAHVAGLVAGGVFPNPLPGADVVTTTTHKTLRGPRGGLI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 255 FYRKGpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGY 334
Cdd:cd00378 235 LTRKG--------------ELAKKINSAVFPGLQGGPHLHVIAAKAVALKEALEPEFKAYAKQVVENAKALAEALKERGF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 335 TLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSF-LAPGGVRIGTPAMTSRGLVEKDFEKIGEFLH 413
Cdd:cd00378 301 KVVSGGTDNHLVLVDLRPKGITGKAAEDALEEAGITVNKNTLPWDPSSpFVPSGIRIGTPAMTTRGMGEEEMEEIADFIA 380
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 75337724 414 RAVTITLDIqeqygkvmkdfnkglvnnKEIDEIKADVEEF 453
Cdd:cd00378 381 RALKDAEDV------------------AVAEEVRKEVAEL 402
|
|
| GlyA |
COG0112 |
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine ... |
9-461 |
0e+00 |
|
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine hydroxymethyltransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439882 Cd Length: 414 Bit Score: 582.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 9 NTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLE 88
Cdd:COG0112 2 LSSLAEVDPEIAEAIEKELERQEEGIELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDEVEQLAIERAKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 89 AFHCnpeKWgVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSS-GGKnisatsiYFENLPYKVDSKTGY 167
Cdd:COG0112 82 LFGA---EH-ANVQPHSGSQANLAVYFALLKPGDTILGMDLAHGGHLTHGSPVNfSGK-------GYNVVSYGVDPETGL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 168 IDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLR 247
Cdd:COG0112 151 IDYDEVRKLALEHKPKLIIAGASAYPRPIDFARFREIADEVGAYLMVDMAHIAGLVAGGLHPSPVPGADVVTTTTHKTLR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 248 GPRAGMIFYRKgpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLAS 327
Cdd:COG0112 231 GPRGGLILCNE---------------ELAKKIDSAVFPGLQGGPLMHVIAAKAVAFKEALTPEFKEYAKQVVKNAKALAE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 328 YLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDT-SFLAPGGVRIGTPAMTSRGLVEKDFE 406
Cdd:COG0112 296 ALAERGFRVVSGGTDNHLVLVDLRSKGLTGKEAEKALERAGITVNKNAIPFDPrSPFVTSGIRIGTPAVTTRGMKEAEME 375
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 75337724 407 KIGEFLHRAVtitldiqeqygkvmkdfnKGLVNNKEIDEIKADVEEFTYDFDMPG 461
Cdd:COG0112 376 EIAELIADVL------------------DNPEDEAVLAEVREEVKELCKRFPLYP 412
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03226 |
PLN03226 |
serine hydroxymethyltransferase; Provisional |
1-468 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 215639 Cd Length: 475 Bit Score: 977.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 1 MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIES 80
Cdd:PLN03226 4 MVSVPKWGNAPLEEVDPEIADIIEKEKRRQWKGLELIASENFTSRAVMEALGSCLTNKYSEGLPGARYYGGNEYIDQIET 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 81 LCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKnISATSIYFENLPYK 160
Cdd:PLN03226 84 LCQKRALEAFRLDPEKWGVNVQPLSGSPANFAVYTALLQPHDRIMGLDLPHGGHLSHGYQTDGKK-ISATSIYFESMPYR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 161 VDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTT 240
Cdd:PLN03226 163 LDESTGLIDYDKLEKKAMLFRPKLIIAGASAYPRDWDYARMRKIADKVGALLMCDMAHISGLVAAQEAASPFEYCDVVTT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 241 STHKSLRGPRAGMIFYRKGPKPAKKGQpEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKA 320
Cdd:PLN03226 243 TTHKSLRGPRGGMIFFRKGPKPPKGQG-EGAVYDYEDKINFAVFPGLQGGPHNHTIAALAVALKQAMTPEFKAYQKQVKA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 321 NAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGL 400
Cdd:PLN03226 322 NAAALANRLMSKGYKLVTGGTDNHLVLWDLRPLGLTGSRVEKVLDLAHITLNKNAVPGDSSALVPGGVRIGTPAMTSRGL 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75337724 401 VEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNN---KEIDEIKADVEEFTYDFDMPGFFISESR 468
Cdd:PLN03226 402 VEKDFEKVAEFLHRAVTIALKIQKEHGKKLKDFKKGLESNdfsKDIEALRAEVEEFATSFPMPGFDKESMK 472
|
|
| PTZ00094 |
PTZ00094 |
serine hydroxymethyltransferase; Provisional |
8-462 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 240264 Cd Length: 452 Bit Score: 785.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 8 GNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSL 87
Cdd:PTZ00094 11 LNQSLKEADPELYELIEKEKERQIEGLELIASENFTSRAVLECLGSCFTNKYAEGLPGNRYYGGNEVVDKIENLCQKRAL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 88 EAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSsGGKNISATSIYFENLPYKVDSKtGY 167
Cdd:PTZ00094 91 EAFGLDPEEWGVNVQPYSGSPANFAVYTALLQPHDRIMGLDLPSGGHLTHGFYT-AKKKVSATSIYFESLPYQVNEK-GL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 168 IDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLR 247
Cdd:PTZ00094 169 IDYDKLEELAKAFRPKLIIAGASAYPRDIDYKRFREICDSVGAYLMADIAHTSGLVAAGVLPSPFPYADVVTTTTHKSLR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 248 GPRAGMIFYRKGPKPakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLAS 327
Cdd:PTZ00094 249 GPRSGLIFYRKKVKP-----------DIENKINEAVFPGLQGGPHNHQIAAIAVQLKEVQSPEWKEYAKQVLKNAKALAA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 328 YLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEK 407
Cdd:PTZ00094 318 ALEKRGYDLVTGGTDNHLVLVDLRPFGITGSKMEKLLDAVNISVNKNTIPGDKSALNPSGVRLGTPALTTRGAKEKDFKF 397
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 75337724 408 IGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGF 462
Cdd:PTZ00094 398 VADFLDRAVKLAQEIQKQVGKKLVDFKKALEKNPELQKLRQEVVEFASQFPFPGI 452
|
|
| PLN02271 |
PLN02271 |
serine hydroxymethyltransferase |
4-462 |
0e+00 |
|
serine hydroxymethyltransferase
Pssm-ID: 215153 Cd Length: 586 Bit Score: 750.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 4 VYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCR 83
Cdd:PLN02271 121 VRAWGNQPLPEADPDIHELMEKEKQRQFKGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTGNQYIDQIERLCC 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 84 SRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDS 163
Cdd:PLN02271 201 ERALAAFGLDSEKWGVNVQPYSCTSANFAVYTGLLLPGDRIMGLDSPSGGHMSHGYYTPGGKKVSGASIFFESLPYKVNP 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 164 KTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTH 243
Cdd:PLN02271 281 QTGYIDYDKLEEKALDFRPKILICGGSSYPREWDYARFRQIADKCGAVLMCDMAHISGLVAAKECVNPFDYCDIVTSTTH 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 244 KSLRGPRAGMIFYRKGPKPAKKGQPEGEV-----YDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQV 318
Cdd:PLN02271 361 KSLRGPRGGIIFYRKGPKLRKQGMLLSHGddnshYDFEEKINFAVFPSLQGGPHNNHIAALAIALKQVATPEYKAYMQQV 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 319 KANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSR 398
Cdd:PLN02271 441 KKNAQALASALLRRKCRLVTGGTDNHLLLWDLTTLGLTGKNYEKVCEMCHITLNKTAIFGDNGTISPGGVRIGTPAMTSR 520
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75337724 399 GLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGF 462
Cdd:PLN02271 521 GCLESDFETIADFLLRAAQIASAVQREHGKLQKEFLKGLQNNKDIVELRNRVEAFASQFAMPGF 584
|
|
| SHMT |
pfam00464 |
Serine hydroxymethyltransferase; |
12-412 |
0e+00 |
|
Serine hydroxymethyltransferase;
Pssm-ID: 395372 Cd Length: 399 Bit Score: 652.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 12 LDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFH 91
Cdd:pfam00464 1 LEDSDPEVFDIIKKEKERQREGIELIASENFTSRAVMEALGSVLTNKYSEGYPGKRYYGGCEHVDEIETLCQDRALEAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 92 CNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSgGKNISATSIYFENLPYKVDSKTGYIDYD 171
Cdd:pfam00464 81 LDPAKWGVNVQPLSGSPANLAVYTALLEPGDRIMGLDLPHGGHLTHGYPVN-SKKISASSKFFESMPYGVDPETGYIDYD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 172 KLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRA 251
Cdd:pfam00464 160 QLEKNAKLFRPKLIVAGTSAYSRLIDYARFREIADEVGAYLMVDMAHISGLVAAGVIPSPFPYADVVTTTTHKTLRGPRG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 252 GMIFYRKGPKPAKKGQPEGeVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLIN 331
Cdd:pfam00464 240 GMIFYRKGVKSVDKTGKEI-LYELEKKINSAVFPGLQGGPHNHVIAAKAVALKQALTPEFKEYQQQVVKNAKALAEALTE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 332 KGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEF 411
Cdd:pfam00464 319 RGYKLVSGGTDNHLVLVDLRPKGLDGARAEKVLEAANITANKNTIPGDKSAFVPSGLRLGTPALTSRGFGEADFEKVAGF 398
|
.
gi 75337724 412 L 412
Cdd:pfam00464 399 I 399
|
|
| SHMT |
cd00378 |
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate ... |
15-453 |
0e+00 |
|
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl group of N5, N10-methylene tetrahydrofolate to glycine resulting in the formation of serine and tetrahydrofolate. Both eukaryotic and prokaryotic SHMT enzymes form tight obligate homodimers; the mammalian enzyme forms a homotetramer comprising four pyridoxal phosphate-bound active sites.
Pssm-ID: 99733 Cd Length: 402 Bit Score: 590.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 15 VDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNp 94
Cdd:cd00378 3 VDPEIAEIIKKENERQRETLELIASENFTSPAVMEAMGSDLTNKYAEGYPGKRYYGGCEYVDEIEDLAIERAKKLFGAE- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 95 ekwGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSggknISATSIYFENLPYKVDSKTGYIDYDKLE 174
Cdd:cd00378 82 ---YANVQPHSGSQANLAVYFALLEPGDTIMGLDLSHGGHLTHGSFTK----VSASGKLFESVPYGVDPETGLIDYDALE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 175 EKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMI 254
Cdd:cd00378 155 KMALEFKPKLIVAGASAYPRPIDFKRFREIADEVGAYLLVDMAHVAGLVAGGVFPNPLPGADVVTTTTHKTLRGPRGGLI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 255 FYRKGpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGY 334
Cdd:cd00378 235 LTRKG--------------ELAKKINSAVFPGLQGGPHLHVIAAKAVALKEALEPEFKAYAKQVVENAKALAEALKERGF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 335 TLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSF-LAPGGVRIGTPAMTSRGLVEKDFEKIGEFLH 413
Cdd:cd00378 301 KVVSGGTDNHLVLVDLRPKGITGKAAEDALEEAGITVNKNTLPWDPSSpFVPSGIRIGTPAMTTRGMGEEEMEEIADFIA 380
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 75337724 414 RAVTITLDIqeqygkvmkdfnkglvnnKEIDEIKADVEEF 453
Cdd:cd00378 381 RALKDAEDV------------------AVAEEVRKEVAEL 402
|
|
| GlyA |
COG0112 |
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine ... |
9-461 |
0e+00 |
|
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine hydroxymethyltransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439882 Cd Length: 414 Bit Score: 582.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 9 NTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLE 88
Cdd:COG0112 2 LSSLAEVDPEIAEAIEKELERQEEGIELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDEVEQLAIERAKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 89 AFHCnpeKWgVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSS-GGKnisatsiYFENLPYKVDSKTGY 167
Cdd:COG0112 82 LFGA---EH-ANVQPHSGSQANLAVYFALLKPGDTILGMDLAHGGHLTHGSPVNfSGK-------GYNVVSYGVDPETGL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 168 IDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLR 247
Cdd:COG0112 151 IDYDEVRKLALEHKPKLIIAGASAYPRPIDFARFREIADEVGAYLMVDMAHIAGLVAGGLHPSPVPGADVVTTTTHKTLR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 248 GPRAGMIFYRKgpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLAS 327
Cdd:COG0112 231 GPRGGLILCNE---------------ELAKKIDSAVFPGLQGGPLMHVIAAKAVAFKEALTPEFKEYAKQVVKNAKALAE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 328 YLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDT-SFLAPGGVRIGTPAMTSRGLVEKDFE 406
Cdd:COG0112 296 ALAERGFRVVSGGTDNHLVLVDLRSKGLTGKEAEKALERAGITVNKNAIPFDPrSPFVTSGIRIGTPAVTTRGMKEAEME 375
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 75337724 407 KIGEFLHRAVtitldiqeqygkvmkdfnKGLVNNKEIDEIKADVEEFTYDFDMPG 461
Cdd:COG0112 376 EIAELIADVL------------------DNPEDEAVLAEVREEVKELCKRFPLYP 412
|
|
| glyA |
PRK00011 |
serine hydroxymethyltransferase; Reviewed |
9-462 |
0e+00 |
|
serine hydroxymethyltransferase; Reviewed
Pssm-ID: 234571 Cd Length: 416 Bit Score: 564.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 9 NTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLE 88
Cdd:PRK00011 3 MDNLAEYDPEIADAIEQELKRQEEHIELIASENFVSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 89 AFHCnpeKWgVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSS-GGKnisatsiYFENLPYKVDSKTGY 167
Cdd:PRK00011 83 LFGA---EY-ANVQPHSGSQANAAVYFALLKPGDTILGMDLAHGGHLTHGSPVNfSGK-------LYNVVSYGVDEETGL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 168 IDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLR 247
Cdd:PRK00011 152 IDYDEVEKLALEHKPKLIIAGASAYSRPIDFKRFREIADEVGAYLMVDMAHIAGLVAAGVHPSPVPHADVVTTTTHKTLR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 248 GPRAGMIFYRKGpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLAS 327
Cdd:PRK00011 232 GPRGGLILTNDE--------------ELAKKINSAVFPGIQGGPLMHVIAAKAVAFKEALEPEFKEYAQQVVKNAKALAE 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 328 YLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDT-SFLAPGGVRIGTPAMTSRGLVEKDFE 406
Cdd:PRK00011 298 ALAERGFRVVSGGTDNHLVLVDLRSKGLTGKEAEAALEEANITVNKNAVPFDPrSPFVTSGIRIGTPAITTRGFKEAEMK 377
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 75337724 407 KIGEFLHRAVtitldiqeqygkvmkdfnKGLVNNKEIDEIKADVEEFTYDFDMPGF 462
Cdd:PRK00011 378 EIAELIADVL------------------DNPDDEAVIEEVKEEVKELCKRFPLYKY 415
|
|
| PRK13034 |
PRK13034 |
serine hydroxymethyltransferase; Reviewed |
9-460 |
5.63e-175 |
|
serine hydroxymethyltransferase; Reviewed
Pssm-ID: 237280 Cd Length: 416 Bit Score: 497.17 E-value: 5.63e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 9 NTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLE 88
Cdd:PRK13034 6 SDSLEEYDDEVFAAINKELERQQDHLELIASENFTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEFVDEVEALAIERAKQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 89 AFHCNpekwGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYY-SSGGKNisatsiyFENLPYKVDSKTGY 167
Cdd:PRK13034 86 LFGCD----YANVQPHSGSQANGAVYLALLKPGDTILGMSLSHGGHLTHGAKvSLSGKW-------YNAVQYGVDRLTGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 168 IDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLR 247
Cdd:PRK13034 155 IDYDEVEELAKEHKPKLIIAGFSAYPRELDFARFREIADEVGALLMVDMAHIAGLVAAGEHPNPFPHAHVVTTTTHKTLR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 248 GPRAGMIFYRKGpkpakkgqpegevyDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLAS 327
Cdd:PRK13034 235 GPRGGMILTNDE--------------EIAKKINSAVFPGLQGGPLMHVIAAKAVAFGEALQPEFKTYAKQVIANAQALAE 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 328 YLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDT-SFLAPGGVRIGTPAMTSRGLVEKDFE 406
Cdd:PRK13034 301 VLKERGYDLVSGGTDNHLLLVDLRPKGLSGKDAEQALERAGITVNKNTVPGDTeSPFVTSGIRIGTPAGTTRGFGEAEFR 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 75337724 407 KIGEFLhravtitLDIQEqygkvmkdfnkGLVNNKEIDEIKADVEEFTYDFDMP 460
Cdd:PRK13034 381 EIANWI-------LDVLD-----------DLGNAALEQRVRKEVKALCSRFPIY 416
|
|
| PRK13580 |
PRK13580 |
glycine hydroxymethyltransferase; |
11-452 |
4.50e-115 |
|
glycine hydroxymethyltransferase;
Pssm-ID: 184161 Cd Length: 493 Bit Score: 347.41 E-value: 4.50e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 11 HLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAF 90
Cdd:PRK13580 29 VILHVEPRIAEAIRQELADQRSSLKLIASENYSSLAVQLAMGNLLTDKYAEGTPGHRFYAGCQNVDTVEWEAAEHAKELF 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 91 HCnPEKWgvnVQPYSGSPANFAAYTALL---------------QPHD----------------RIMGLDLPSGGHITHGY 139
Cdd:PRK13580 109 GA-EHAY---VQPHSGADANLVAFWAILahkvespaleklgakTVNDlteedwealraelgnqRLLGMSLDSGGHLTHGF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 140 YssggKNISatSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHN 219
Cdd:PRK13580 185 R----PNIS--GKMFHQRSYGVDPDTGLLDYDEIAALAREFKPLILVAGYSAYPRRVNFAKLREIADEVGAVLMVDMAHF 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 220 SALVAA---QEAADPFEYCDVVTTSTHKSLRGPRAGMIFyrkgpkpAKKgqpegevyDFDAKINSAVfPALQSGPHNNKI 296
Cdd:PRK13580 259 AGLVAGkvfTGDEDPVPHADIVTTTTHKTLRGPRGGLVL-------AKK--------EYADAVDKGC-PLVLGGPLPHVM 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 297 GALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAV 376
Cdd:PRK13580 323 AAKAVALAEARTPEFQKYAQQVVDNARALAEGFLKRGARLVTGGTDNHLVLIDVTSFGLTGRQAESALLDAGIVTNRNSI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 377 FGD------TSflapgGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKdfNKGLVNNKEIDEIKADV 450
Cdd:PRK13580 403 PSDpngawyTS-----GIRLGTPALTTLGMGSDEMDEVAELIVKVLSNTTPGTTAEGAPSK--AKYELDEGVAQEVRARV 475
|
..
gi 75337724 451 EE 452
Cdd:PRK13580 476 AE 477
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
93-257 |
1.44e-23 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 97.07 E-value: 1.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 93 NPEKWGVNVQPySGSPANFAAYTALLQPHDRIMGLDLPSGGHITHgyyssggkniSATSIYFENLPYKVDSKTGY-IDYD 171
Cdd:cd01494 14 QPGNDKAVFVP-SGTGANEAALLALLGPGDEVIVDANGHGSRYWV----------AAELAGAKPVPVPVDDAGYGgLDVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 172 KLEEKAMDFRPKLIICGGTSYPR--EWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGP 249
Cdd:cd01494 83 ILEELKAKPNVALIVITPNTTSGgvLVPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIPEGGADVVTFSLHKNLGGE 162
|
....*...
gi 75337724 250 RAGMIFYR 257
Cdd:cd01494 163 GGGVVIVK 170
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
42-397 |
1.92e-06 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 49.61 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 42 FTSVAVMEALgscltNKYSEGMPGNRY---YGGTEFIDEIESLCRSRSLEAFhcNPEkwgVNVQPYSGSPAN-FAAYTAL 117
Cdd:pfam00155 14 DTLPAVAKAE-----KDALAGGTRNLYgptDGHPELREALAKFLGRSPVLKL--DRE---AAVVFGSGAGANiEALIFLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 118 LQPHDRIMgLDLPsgghiTHGYYSSGGKNISATSIYFenlPYKvDSKTGYIDYDKLEEkAMDFRPKLII-CG-----GTS 191
Cdd:pfam00155 84 ANPGDAIL-VPAP-----TYASYIRIARLAGGEVVRY---PLY-DSNDFHLDFDALEA-ALKEKPKVVLhTSphnptGTV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 192 YPREwDYARFRAVADKVGAFLLCDMAHnSALVAAQEAADPF-----EYCDVVTTST-HKS--LRGPRAGMIFyrkgpkpa 263
Cdd:pfam00155 153 ATLE-ELEKLLDLAKEHNILLLVDEAY-AGFVFGSPDAVATrallaEGPNLLVVGSfSKAfgLAGWRVGYIL-------- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 264 kkgqpegevydfdakINSAVFPALQ--SGPHNNKIGALAVALKQVMAPSFKV-----YAKQVKANAACLASYLINKGYTL 336
Cdd:pfam00155 223 ---------------GNAAVISQLRklARPFYSSTHLQAAAAAALSDPLLVAseleeMRQRIKERRDYLRDGLQAAGLSV 287
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75337724 337 VTDgtDNHLILW-DLRPlgltgnkvEKVCELCYITLNRN--AVFGDTSFLAPGGVRIGTPAMTS 397
Cdd:pfam00155 288 LPS--QAGFFLLtGLDP--------ETAKELAQVLLEEVgvYVTPGSSPGVPGWLRITVAGGTE 341
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
105-258 |
4.20e-05 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 45.28 E-value: 4.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 105 SGSPANFAAYTALLQPHDRIMGldlpsgGHITHGYYSSGGKNISATSIYFENLPYKVDsktGYIDYDKLEE--KAMDF-- 180
Cdd:pfam01212 55 SGTAANQLALMAHCQRGDEVIC------GEPAHIHFDETGGHAELGGVQPRPLDGDEA---GNMDLEDLEAaiREVGAdi 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75337724 181 --RPKLI-------ICGGTSYPREWdYARFRAVADKVGAFLLCDMAH--NSALVAAQEAADPFEYCDVVTTSTHKSLRGP 249
Cdd:pfam01212 126 fpPTGLIslenthnSAGGQVVSLEN-LREIAALAREHGIPVHLDGARfaNAAVALGVIVKEITSYADSVTMCLSKGLGAP 204
|
....*....
gi 75337724 250 RAGMIFYRK 258
Cdd:pfam01212 205 VGSVLAGSD 213
|
|
| |
