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Conserved domains on  [gi|28201787|sp|Q9NV56|]
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RecName: Full=MRG/MORF4L-binding protein; AltName: Full=MRG-binding protein; AltName: Full=Up-regulated in colon cancer 4; Short=Urcc4

Protein Classification

EAF7 family protein( domain architecture ID 10006)

EAF7 family protein similar to Homo sapiens MRG/MORF4L-binding protein, a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A

Gene Ontology:  GO:0006355|GO:0006325

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eaf7 super family cl06786
Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss: ...
 36-112 8.18e-13

Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss:P53911 is part of NuA4, the only essential histone acetyltransferase complex in Saccharomyces cerevisiae involved in global histone acetylation.


The actual alignment was detected with superfamily member pfam07904:

Pssm-ID: 429728  Cd Length: 97  Bit Score: 61.87  E-value: 8.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28201787    36 EVCLFHAMLGHKPVGVNRHFHMICIRD-----KFSQNIGRQVPSKVIWDHLSTMYDMQALHESE----ILPFPNPERN-- 104
Cdd:pfam07904   2 EIRLFKWIIRFKPAGIHKHFRMLAISErlnnqGYDPKSGKHTRIPDIWKKLGTLYNLDALDEREdvppDEDYDDDEDSei 81

                          90
                  ....*....|....*.
gi 28201787   105 --------FVLPEEII 112
Cdd:pfam07904  82 iqfrkyrdFELPWDEY 97
 
Name Accession Description Interval E-value
Eaf7 pfam07904
Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss: ...
 36-112 8.18e-13

Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss:P53911 is part of NuA4, the only essential histone acetyltransferase complex in Saccharomyces cerevisiae involved in global histone acetylation.


Pssm-ID: 429728  Cd Length: 97  Bit Score: 61.87  E-value: 8.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28201787    36 EVCLFHAMLGHKPVGVNRHFHMICIRD-----KFSQNIGRQVPSKVIWDHLSTMYDMQALHESE----ILPFPNPERN-- 104
Cdd:pfam07904   2 EIRLFKWIIRFKPAGIHKHFRMLAISErlnnqGYDPKSGKHTRIPDIWKKLGTLYNLDALDEREdvppDEDYDDDEDSei 81

                          90
                  ....*....|....*.
gi 28201787   105 --------FVLPEEII 112
Cdd:pfam07904  82 iqfrkyrdFELPWDEY 97
 
Name Accession Description Interval E-value
Eaf7 pfam07904
Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss: ...
 36-112 8.18e-13

Chromatin modification-related protein EAF7; The S. cerevisiae member of this family Swiss:P53911 is part of NuA4, the only essential histone acetyltransferase complex in Saccharomyces cerevisiae involved in global histone acetylation.


Pssm-ID: 429728  Cd Length: 97  Bit Score: 61.87  E-value: 8.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28201787    36 EVCLFHAMLGHKPVGVNRHFHMICIRD-----KFSQNIGRQVPSKVIWDHLSTMYDMQALHESE----ILPFPNPERN-- 104
Cdd:pfam07904   2 EIRLFKWIIRFKPAGIHKHFRMLAISErlnnqGYDPKSGKHTRIPDIWKKLGTLYNLDALDEREdvppDEDYDDDEDSei 81

                          90
                  ....*....|....*.
gi 28201787   105 --------FVLPEEII 112
Cdd:pfam07904  82 iqfrkyrdFELPWDEY 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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