|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
45-479 |
1.59e-166 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 477.45 E-value: 1.59e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 45 EVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLG 124
Cdd:cd13132 1 EAKKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFANVTGFSILLGLASALDTLCGQAFGAKNYKLVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:cd13132 81 VYLQRALVILLLCCVPISLLWLNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 205 ALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYI-FSGTCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLE 283
Cdd:cd13132 161 ALLLNILLNYLLVFVLGLGFIGAALATSISYWLIVVLLLLYIfFSKGHKATWGGFSREAFRGWGPFLKLAIPSALMLCLE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 284 VWYLMAVILFAGYLKnAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAIS 363
Cdd:cd13132 241 WWAFEILVLLAGLLP-GTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIVALILSLVIGVVVA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 364 IALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYKL 443
Cdd:cd13132 320 ILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGRQKLGAYVNLVAYYLIGLPVGLLLAFVL 399
|
410 420 430
....*....|....*....|....*....|....*.
gi 75180368 444 NFGVMGIWCGMLTGTVVQTIVLTWMICRTNWDTEAA 479
Cdd:cd13132 400 GLGLKGLWIGLIAGLILQAVILLLIILRTDWDKEAE 435
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
55-395 |
7.15e-55 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 187.07 E-value: 7.15e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 55 PAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIaGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVIL 134
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVF-MFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 135 NVTAVILSLLYIFAA-PILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLT 213
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIdPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 214 WFVIEGL--QWGTAGLAVVLNASWWFIVVAQLVYIFSG-TCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLEVWYLMAV 290
Cdd:TIGR00797 160 YILIFGKfgFLGIVGAALATVISYWLMFLLLLYYIKKAkKIGLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFALL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 291 ILFAGYLKnaEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAISIALLIFR 370
Cdd:TIGR00797 240 ALLVARLG--SIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFR 317
|
330 340
....*....|....*....|....*
gi 75180368 371 DKYPSLFVGDEEVIIVVKDLTPILA 395
Cdd:TIGR00797 318 EFIARLFTNDPEVLELAAIYLIFVA 342
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
47-468 |
2.95e-54 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 188.04 E-value: 2.95e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVI-AGFSFGVMLGMGSAleTLCGQAFGAGKLSMLGV 125
Cdd:COG0534 8 KLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFfLLIALGIGLGVGGT--ALVAQALGAGDREEARR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 126 YLQRS-WVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:COG0534 86 VLGQAlLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 205 ALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGEAWSGFSWEA-FHNLWSFVRLSLASAVMLCLE 283
Cdd:COG0534 166 GNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPdRKILKRILRIGLPAGLQQLAE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 284 VWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAIS 363
Cdd:COG0534 246 SLGFLVLNALVARL--GTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGLLLA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 364 IALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYkL 443
Cdd:COG0534 324 LLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAYLLAF-L 402
|
410 420
....*....|....*....|....*
gi 75180368 444 NFGVMGIWCGMLTGTVVQTIVLTWM 468
Cdd:COG0534 403 GLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
276-438 |
6.25e-28 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 109.19 E-value: 6.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 276 SAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITS 355
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHL--GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 356 TVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCyYVFGIPF 435
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIIS-LLLNIPL 158
|
...
gi 75180368 436 GLL 438
Cdd:pfam01554 159 NYL 161
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
40-467 |
6.09e-24 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 104.12 E-value: 6.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 40 KEFNVEVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENS----VIAGFSfGVMLgmgsALETLCGQAF 115
Cdd:PRK01766 5 QKYKSEARQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLAAVAIGTSiwlpVILFGH-GLLL----ALTPIVAQLN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 116 GAGKLSMLG-VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSK 194
Cdd:PRK01766 80 GAGRRERIAhQVRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 195 IMVMAAISAVALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGT------CGEAWSGFSWEAFH 264
Cdd:PRK01766 160 TKPTMVIGFLGLLINIPLNYIFIYGKfgfpELGGVGCGVATAIVYWVMFLAMLIYIKRARrfrdfrLFKGLYKPDWAVIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 265 NLWsfvRLSLASAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTA 344
Cdd:PRK01766 240 RLL---KLGLPIGLAIFFEVSLFAVVTLLVSPL--GTVTVAAHQIALNFSSLLFMLPLSLAMALTIRVGFELGAGRTLDA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 345 KFSLLVAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVN 424
Cdd:PRK01766 315 RQYAYIGLAVGLGMALLTAIFLVLFREQIALLYTDDPEVVALASHLLLFAALFQFSDAIQVIGSGALRGYKDTRVIFFIT 394
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 75180368 425 IVCYYVFGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTW 467
Cdd:PRK01766 395 FIAYWVLGLPLGYILALTDPMGPFGFWIGLIIGLTAAAILLLL 437
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
45-479 |
1.59e-166 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 477.45 E-value: 1.59e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 45 EVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLG 124
Cdd:cd13132 1 EAKKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFANVTGFSILLGLASALDTLCGQAFGAKNYKLVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:cd13132 81 VYLQRALVILLLCCVPISLLWLNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 205 ALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYI-FSGTCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLE 283
Cdd:cd13132 161 ALLLNILLNYLLVFVLGLGFIGAALATSISYWLIVVLLLLYIfFSKGHKATWGGFSREAFRGWGPFLKLAIPSALMLCLE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 284 VWYLMAVILFAGYLKnAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAIS 363
Cdd:cd13132 241 WWAFEILVLLAGLLP-GTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIVALILSLVIGVVVA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 364 IALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYKL 443
Cdd:cd13132 320 ILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGRQKLGAYVNLVAYYLIGLPVGLLLAFVL 399
|
410 420 430
....*....|....*....|....*....|....*.
gi 75180368 444 NFGVMGIWCGMLTGTVVQTIVLTWMICRTNWDTEAA 479
Cdd:cd13132 400 GLGLKGLWIGLIAGLILQAVILLLIILRTDWDKEAE 435
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
55-395 |
7.15e-55 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 187.07 E-value: 7.15e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 55 PAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIaGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVIL 134
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVF-MFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 135 NVTAVILSLLYIFAA-PILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLT 213
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIdPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 214 WFVIEGL--QWGTAGLAVVLNASWWFIVVAQLVYIFSG-TCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLEVWYLMAV 290
Cdd:TIGR00797 160 YILIFGKfgFLGIVGAALATVISYWLMFLLLLYYIKKAkKIGLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFALL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 291 ILFAGYLKnaEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAISIALLIFR 370
Cdd:TIGR00797 240 ALLVARLG--SIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFR 317
|
330 340
....*....|....*....|....*
gi 75180368 371 DKYPSLFVGDEEVIIVVKDLTPILA 395
Cdd:TIGR00797 318 EFIARLFTNDPEVLELAAIYLIFVA 342
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
47-468 |
2.95e-54 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 188.04 E-value: 2.95e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVI-AGFSFGVMLGMGSAleTLCGQAFGAGKLSMLGV 125
Cdd:COG0534 8 KLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFfLLIALGIGLGVGGT--ALVAQALGAGDREEARR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 126 YLQRS-WVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:COG0534 86 VLGQAlLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 205 ALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGEAWSGFSWEA-FHNLWSFVRLSLASAVMLCLE 283
Cdd:COG0534 166 GNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPdRKILKRILRIGLPAGLQQLAE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 284 VWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAIS 363
Cdd:COG0534 246 SLGFLVLNALVARL--GTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGLLLA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 364 IALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYkL 443
Cdd:COG0534 324 LLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAYLLAF-L 402
|
410 420
....*....|....*....|....*
gi 75180368 444 NFGVMGIWCGMLTGTVVQTIVLTWM 468
Cdd:COG0534 403 GLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
45-467 |
9.80e-46 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 165.37 E-value: 9.80e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 45 EVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSFGVMlGMGSALETLCGQAFGAGKLSMLG 124
Cdd:cd13131 1 ELRALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLAAVALGSSLWFPVFTFGM-GLLLAVTPLVAQAHGAGDRRRIR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:cd13131 80 RAVRQGLWLALLLSLPLMLLLWLAPPILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 205 ALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGT------CGEAWSGFSWEAFHNLWsfvRLSL 274
Cdd:cd13131 160 ALVLNIPLNYVLIFGKfglpALGGAGAGLATAIVYWLMFLALAFYIRRHKrfrryrLFARFWRPDWARLKELL---RLGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 275 ASAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVIT 354
Cdd:cd13131 237 PIGLTIFFEVSLFAAVALLMGRL--GTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLVGLGL 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 355 STVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIP 434
Cdd:cd13131 315 GVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRVPFLLALISYWGIGLP 394
|
410 420 430
....*....|....*....|....*....|...
gi 75180368 435 FGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTW 467
Cdd:cd13131 395 LGYLLAFTTGLGAFGVWIGLIIGLALAAILLLW 427
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
47-474 |
7.70e-39 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 146.50 E-value: 7.70e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIaGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVY 126
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVGLATQVL-WLLLVLNMALGTGTVALVSQSYGAGDYERARRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 127 LQRSWVILNVTAVILSLL-YIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVA 205
Cdd:cd13137 80 LGQSLLLALLLSLPLALLgLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 206 LVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGTCG--EAWSGFSWEaFHNLWSFVRLSLASAVM 279
Cdd:cd13137 160 NVLNIVLDYVLIFGLwgfpGLGVAGAALATVISRVVGALLLLFLLLRGRLPikISFKGFRLD-RKIIKKLLRIGLPAGLE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 280 LCleVWYLMAVILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIG 359
Cdd:cd13137 239 QL--LRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFM 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 360 LAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLL 439
Cdd:cd13137 317 GLLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYLL 396
|
410 420 430
....*....|....*....|....*....|....*
gi 75180368 440 GYKLNFGVMGIWCGMLTGTVVQTIVLTWMICRTNW 474
Cdd:cd13137 397 GFVLGLGLTGIWLAMFVDTIVRAILLLYRFRKGKW 431
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
46-474 |
8.90e-32 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 126.81 E-value: 8.90e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 46 VKKLWYLAGPAIFMSITQYSLGAATQVFAGHI-STIALAAVSVeNSVIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLG 124
Cdd:cd13138 2 LKTLLLFALPLLLSNLLQQLYNLVDLLIVGQFlGVAALAAVSN-GSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTP--AISSATGIFSIYMIPQIFAYAVNYPTAkFLQSQ--SKIMVMaa 200
Cdd:cd13138 81 KAVGTLLVLFLILGIVLTILGLLFAPPILRLMNTPaeILELAVSYLRICFLGIPFIFGYNAYSA-ILRGLgdSKTPLY-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 201 ISAVALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIFSGtcgEAWSGFSWEAFH----NLWSFVRLSLAS 276
Cdd:cd13138 158 FVIIACVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRKK---KLPFKLSLKDFRfdkeILKEILKIGLPS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 277 AVMlclevwylMAVILFAGYLKNAEIS------VAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLV 350
Cdd:cd13138 235 ALQ--------QSLVSISFLIINSIVNsygvvaSAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRT 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 351 AVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYV 430
Cdd:cd13138 307 GIIISLIIGLIIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWL 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 75180368 431 FGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTWMICRTNW 474
Cdd:cd13138 387 VRIPLAYLLSRLTGLGLFGIWLAMPISNILSAIICIIYYRKGRW 430
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
53-466 |
1.73e-28 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 117.04 E-value: 1.73e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 53 AGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSFGVMlGMGSALETLCGQAFGAGKLSMLGVYLQRS-W 131
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGV-GLSVGTSALISQAIGAGDEEKARRVLVQSiV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 132 VILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVL 211
Cdd:cd12082 80 LAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNIL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 212 LTWFVIEGLQ---WGTAGLAVVLNASWWFIVVAQLVYIFSGTcgeAWSGFSWEAFH----NLWSFVRLSLASAVMLCLEV 284
Cdd:cd12082 160 LDPLLIFGLGppeLGIAGAALATVISYVIGALLLLIYLRKGK---KILKFKLSLLKpdleLLRRLLRIGLPSAIQNSLLS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 285 WYLMAVILFAGYLKNAEiSVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAISI 364
Cdd:cd12082 237 LGLLIIVAIVAAFGGAA-ALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 365 ALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYkLN 444
Cdd:cd12082 316 LILLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLAY-LG 394
|
410 420
....*....|....*....|..
gi 75180368 445 FGVMGIWCGMLTGTVVQTIVLT 466
Cdd:cd12082 395 LGLYGIWLALVISLILAALVLL 416
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
47-451 |
3.49e-28 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 116.46 E-value: 3.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGH-ISTIALAAVSVENSVIAG-FSFGVMLGMGSAleTLCGQAFGAGKLSMLG 124
Cdd:cd13143 4 KLFLKFALPAIIGMLVNGLYNIVDGIFVGHgVGALALAAVNLVFPIIMLlMALGLMIGVGGA--SLISRRLGAGDREKAN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRS-WVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISA 203
Cdd:cd13143 82 RIFSTAlLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGML 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 204 VALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGEAWSGFSWE-AFHNLWSFVRLSLASAVM-LC 281
Cdd:cd13143 162 IGAVLNIILDPLFIFVLGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRFKlSLKIIKEILALGFPSFLMqLS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 282 LEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLA 361
Cdd:cd13143 242 SSVVTIVLNLTLLGYG--GDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 362 ISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSG--VAVGAGWQAVVayVNIVCYYVFGIPFGLLL 439
Cdd:cd13143 320 LFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGyfQAIGKAKRAAL--LSLLRQGLFLIPLLLIL 397
|
410
....*....|..
gi 75180368 440 GYKlnFGVMGIW 451
Cdd:cd13143 398 PRL--FGLDGIW 407
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
276-438 |
6.25e-28 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 109.19 E-value: 6.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 276 SAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITS 355
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHL--GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 356 TVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCyYVFGIPF 435
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIIS-LLLNIPL 158
|
...
gi 75180368 436 GLL 438
Cdd:pfam01554 159 NYL 161
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
46-474 |
6.70e-28 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 115.70 E-value: 6.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 46 VKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAvsvenSVIAG--FSFGVMLGMGSA--LETLCGQAFGAGKLS 121
Cdd:cd13133 4 YREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAA-----SGPAGvlYFAILMLFFGLSsgVQVFVAQYNGAGRYS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 122 MLGVYLQRSWVILNVTAVILSLLYIFAAP-ILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAA 200
Cdd:cd13133 79 RIGRVLWQGLYFSLLLAPLLALLSALAAPlLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 201 ISAVALVLHVLLTWFVIEG----LQWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGE-----AWSGFSWEAFhnlWSFVR 271
Cdd:cd13133 159 ANLVMVVVNIVLDYALIFGklgfPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRrfglrRAWRFDRELL---RRILR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 272 LSLASAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVA 351
Cdd:cd13133 236 LGLPSGLQFFLDVGAFTVFFLLIGRL--GTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 352 VITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPIL---AVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCY 428
Cdd:cd13133 314 LKLALAYMLLLGILFLLFPELLLSIFTPGADFALIAELAVPLLrfvAAYILFDALALVFAGALRGAGDTRFVMLAELIVA 393
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 75180368 429 YVFGIPFGLLLGYkLNFGVMGIWCGMLTGTVVQTIVLTWMICRTNW 474
Cdd:cd13133 394 WLYLLPPAYLLVV-LGAGLAGAWTVETVYVIVLALIFLLRFRSGKW 438
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
55-215 |
3.68e-27 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 106.88 E-value: 3.68e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 55 PAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSvIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVIL 134
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANS-IASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 135 NVTAVILSLL-YIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLT 213
Cdd:pfam01554 80 LLLSLPIALLvLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLN 159
|
..
gi 75180368 214 WF 215
Cdd:pfam01554 160 YL 161
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
46-474 |
1.10e-26 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 112.29 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 46 VKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIaGFSFGVMLGMGSALETLCGQAFGAGKLSMLGV 125
Cdd:cd13142 10 LRTLLKLAWPIIVSNLLQVAYNLADTFWLGRLGADAVAAPSISWPLI-FLFISLGGGLTVAGTALVAQYTGAGDYDKANK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 126 YLQRSWVILNVTAVILSLL-YIFAAPILAFIGQTPA--ISSATGIFSIYMIPQIFAYAVNYPTAkFLQSQSKIMVMAAIS 202
Cdd:cd13142 89 VAGQTFSFVIILSLILAVLgYILSRPLLLLLIGAPEevYPLALAYLRIIFLGLPFMFIFFVFNS-LLRGIGDTKTPMKIM 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 203 AVALVLHVLLTWFVIEGLQ----WGTAGLAVVLNASWWFIVVAQLVYIFSGTCG------EAWSGFSWeafhnLWSFVRL 272
Cdd:cd13142 168 FGSVLLNVILDPLLIFGIGpfpgLGVAGAALATVISRGIAAVIGLYLLFKGRVGlkislrDLKPDWEW-----LKKIFRI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 273 SLASAVMLC---LEVWYLMAVILFAGylknaEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLL 349
Cdd:cd13142 243 GLPSSIEQSaraLGFTVMTALVAGFG-----TVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVK 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 350 VAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYY 429
Cdd:cd13142 318 KAALLIFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLW 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 75180368 430 VFGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTWMICRTNW 474
Cdd:cd13142 398 VIRIPLAYLLAYVLGLGVTGIWIAMAISNIVAALIALAWFKRGTW 442
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
47-467 |
1.10e-25 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 109.13 E-value: 1.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIaGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVY 126
Cdd:cd13134 3 LSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQIL-FLLILIFSFISTGTSILIAQYLGAKDKKKARQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 127 LQRSWVILNVTAVILSLL-YIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVA 205
Cdd:cd13134 82 AGVALLFNLLLGLVFSLLlLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 206 LVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFsgtCGEAWSGFSWEAFHNLWSFVRLSLASAVMLC 281
Cdd:cd13134 162 NILNIVGNYLLIFGWfglpKLGVAGVAISTVISRAVGLVLLFILLF---RKLKIRFRLKDLRPFPKKLLKKILKIGLPSA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 282 LE--VWYLMAVILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIG 359
Cdd:cd13134 239 GEelSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 360 LAISIALLIFRDKYPSLFVGDEEVIivvKDLTPILAVSIVinnVQP------VLSGVAVGAGWQAVVAYVNIVCYYVFGI 433
Cdd:cd13134 319 LAVALLLALFREPILGLFTDDPEII---ALGKTLLLISIL---LEPgrafniVLIGSLRAAGDARFPVLIGIISMWGISV 392
|
410 420 430
....*....|....*....|....*....|....
gi 75180368 434 PFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTW 467
Cdd:cd13134 393 PLAYLLGIVLGLGLLGVWIAFAADEWVRGIIMLW 426
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
40-467 |
6.09e-24 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 104.12 E-value: 6.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 40 KEFNVEVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENS----VIAGFSfGVMLgmgsALETLCGQAF 115
Cdd:PRK01766 5 QKYKSEARQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLAAVAIGTSiwlpVILFGH-GLLL----ALTPIVAQLN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 116 GAGKLSMLG-VYLQRSWVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSK 194
Cdd:PRK01766 80 GAGRRERIAhQVRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 195 IMVMAAISAVALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGT------CGEAWSGFSWEAFH 264
Cdd:PRK01766 160 TKPTMVIGFLGLLINIPLNYIFIYGKfgfpELGGVGCGVATAIVYWVMFLAMLIYIKRARrfrdfrLFKGLYKPDWAVIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 265 NLWsfvRLSLASAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTA 344
Cdd:PRK01766 240 RLL---KLGLPIGLAIFFEVSLFAVVTLLVSPL--GTVTVAAHQIALNFSSLLFMLPLSLAMALTIRVGFELGAGRTLDA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 345 KFSLLVAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVN 424
Cdd:PRK01766 315 RQYAYIGLAVGLGMALLTAIFLVLFREQIALLYTDDPEVVALASHLLLFAALFQFSDAIQVIGSGALRGYKDTRVIFFIT 394
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 75180368 425 IVCYYVFGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTW 467
Cdd:PRK01766 395 FIAYWVLGLPLGYILALTDPMGPFGFWIGLIIGLTAAAILLLL 437
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
47-471 |
8.76e-19 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 88.39 E-value: 8.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIA-LAAVSVENSVIAGFSFGVM-LGMGSAleTLCGQAFGAGKLSMLG 124
Cdd:cd13136 3 REILALALPAILSNITVPLLGLVDTAVVGHLGSAAyLGAVALGTTIFNTLFWLFGfLRMGTT--GLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 125 VYLQRS-WVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISA 203
Cdd:cd13136 81 ALLVRAlLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 204 VALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGEAWSG----FSWEAFHNLWSFVRLSLASavM 279
Cdd:cd13136 161 VGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLsrrlPSKAALKRLFKLNRDIFIR--T 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 280 LCLEVWYLMAVILFAGYlknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIG 359
Cdd:cd13136 239 LALLAAFLFFTALAARL---GDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 360 LAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLL 439
Cdd:cd13136 316 VLLALLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLLFLLV 395
|
410 420 430
....*....|....*....|....*....|..
gi 75180368 440 GYklnFGVMGIWCGMLTGTVVQTIVLTWMICR 471
Cdd:cd13136 396 PL---WGNHGLWLALILFMLLRGLTLALRLPR 424
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
73-476 |
1.65e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 87.67 E-value: 1.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 73 FAGHISTIALAAVSVENSVIAgFSFGVMLGMGSALETLCGQAFGAGKLSMLGV-YLQRSWVILNVTAVILSLLYIFAAPI 151
Cdd:cd13139 40 FVSRLGALAIATVGLTESVLT-IVYSIAIGLSMAATALVARRIGEKDPEGAGFaAVQAILLGVALSLILSILGYFFAEDI 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 152 LAFIGQTPAIssatgifsiymipqiFAYAVNYPTAKFLQSQSKIMV-----------MAAISAVALVL----HVLLTWFV 216
Cdd:cd13139 119 LSLMGASPAV---------------IAEGYGYTRIMFGGNGFIMLLflingifrgagDAAIAMRSLWLanglNIILDPLF 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 217 IEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSG----TCGEAWSGFSWEAfhnLWSFVRLSLASAVMLCLEV--WY 286
Cdd:cd13139 184 IFGLgpipAMGVTGAAIATTIGRSIGVLYQLYHLFKGkgriQIRRRHLKLDWAI---IKKIIKIAVGGILQFLIASssWI 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 287 LMAVILfagyLKNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAISIAL 366
Cdd:cd13139 261 FLVRII----AEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKYNMVFLGIVSLVF 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 367 LIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGYKLNFG 446
Cdd:cd13139 337 FLFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGFWLFQIPLAYLLARHLNLG 416
|
410 420 430
....*....|....*....|....*....|
gi 75180368 447 VMGIWCGMLTGTVVQTIVLTWMICRTNWDT 476
Cdd:cd13139 417 PKGVFIAIPIAETVLAIAAIILFRRGKWKT 446
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
46-245 |
5.35e-13 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 70.56 E-value: 5.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 46 VKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSvIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLGV 125
Cdd:COG0534 228 LKRILRIGLPAGLQQLAESLGFLVLNALVARLGTAAVAAYGIALR-IESLAFMPALGLGQAAQPLVGQNLGAGDYDRARR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 126 YLQRS-WVILNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAV 204
Cdd:COG0534 307 AARLAlLLALGIGLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLL 386
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 75180368 205 ALVLHVLLTWFVIEGLQWGTAGLAVVLNASWWFIVVAQLVY 245
Cdd:COG0534 387 RLWLVRLPLAYLLAFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
47-474 |
8.26e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 70.25 E-value: 8.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVeNSVIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVY 126
Cdd:cd13140 5 KTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSDAVAAVGT-AGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEARKY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 127 LQRSwVILNVTAVIL--SLLYIFAAPILAF--IGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFL-QSQSKIMVMaaI 201
Cdd:cd13140 84 ARNA-LQLNLLLGILygLLLLLFAKPLIGFfnLGDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNaLGDSKTPFI--I 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 202 SAVALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGTcGEAWSGFSWEAFHN--LWSFVRLSLA 275
Cdd:cd13140 161 NAIGLVLNIILDPLLIFGFgpfpALGVAGAALATVLAQAIVFLLFLYALKKKK-GLFLKIRILKRPDRkyIKEILKLGLP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 276 SAVMLCL-EVWYLMAVILFAGYlknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVIT 354
Cdd:cd13140 240 VALQSILfALISMILARIIASF---GPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRKGYKTALKI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 355 STVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCyYVFGIP 434
Cdd:cd13140 317 ASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLGRTKPPAIISIVF-NGLRIP 395
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 75180368 435 FGLLLGYkLNFGVMGIWCGMLTGTVVQTIVLTWMICRTNW 474
Cdd:cd13140 396 LALLLSP-TGLGLNGIWWAISISSILKGIILTIWFLLYKK 434
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
67-471 |
3.33e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 68.20 E-value: 3.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 67 GAATQVFAGHISTIALAAVSVENSVIAG--------------FSFGVMLGMGSaletLCGQAFGAGKLSMLGVYLQRSWV 132
Cdd:cd13146 20 GQLFQLLYNITDTIWISMIDPSDPALVGgiglvfplgmiflaLGNGIQVGVSS----LLARAIGAQRAKELDQAADSGLA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 133 I-LNVTAVILSLLYIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVL 211
Cdd:cd13146 96 LaLLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAMLIGTVVNIV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 212 LTWFVIEGLQWGTAGLAVVLNASwWFIVVAQLVYIFSGTCGE-----AWSGFSWEAFHNLwsfvrLSLASAVMLCLEVWY 286
Cdd:cd13146 176 LDPILIFVFDMGVKGAALATVLA-QAISLLYLLYVFLIGKSNvtihiKLSNISSSVIVEI-----LRVGLPQMLLQLISS 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 287 LMAVILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVIGLAISIAL 366
Cdd:cd13146 250 ISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILGIVVVLVLVLGY 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 367 LIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGV--AVGAGWQAVVayVNIVCYYVFGIPFGLLLGYKLN 444
Cdd:cd13146 330 VLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFfqAIGKAWPSLL--LTLIRHVFLSVPVVYLLAYVFG 407
|
410 420
....*....|....*....|....*..
gi 75180368 445 FGVMGIWCGMLTGTVVqTIVLTWMICR 471
Cdd:cd13146 408 KGITGVYFGIVSANFF-TALLAMFWGL 433
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
47-465 |
1.43e-11 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 66.16 E-value: 1.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAV-SVENSVIAGFSFGVMLGMGSALetLCGQAFGAGKLSMLGV 125
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVgNVTTPFNTITGFLGSISIGFTI--LGSQSVGAKDIKRIND 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 126 YLQRSWVILNVTAVILSLLYIFAAPIL-AFIGQTPAI----SSATGIFSIYMIPQ--IFAYAVNYPTAKflqsQSKIMVM 198
Cdd:cd13135 79 YAISSIVYNSIIGVILFLLWLFGARIIfVLFGVDGQIlgysINYVRIFSIYLLLLgiLFTFSSILQGIG----ETKPIMY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 199 AAISAValVLHVLLTWFVIEGL----QWGTAG------LAVVLNASWWFIVVAQLVYIFSGTCGEAWSGFSWEAFHNLws 268
Cdd:cd13135 155 GGIIKN--LLNVILDYVLIFGNfgfpRLGIIGaaiattIANVLNLIILVYLCRKIKKLTFKLSNTKVLKANIRPYKFT-- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 269 fVRLSLASAVMLCLEVWYLMAVILFAGYLKNAEISVAALSICMNILGWTAMIAIGmNAAVSVrVSNELGAKHPRTAKFSL 348
Cdd:cd13135 231 -IKLGLPLGGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYS-SAALTL-VGESIGKKDLKEALRIG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 349 LVAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIivvKDLTPILAVSIVINNVQPVlsGVAVGAGWQAVVAYVNIVCY 428
Cdd:cd13135 308 NICLGLGLLIYIAAAIVFLAFPYKILSLFTNDPELI---NYSIPYLIFIIIILFFKSI--NIVYGFAIRAIGDTKWMLYT 382
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 75180368 429 YVFG----IPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVL 465
Cdd:cd13135 383 QIIGtiivVSVALLLIFVFKLGLAGVYITLFIDEIIRAIIN 423
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
44-467 |
9.55e-11 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 64.00 E-value: 9.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 44 VEVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSF---GVMLGMGS--ALETLCGQAFGAG 118
Cdd:PRK00187 7 TELKAILRLAGPLIASQLAHMLMVFTDTLMMGRLGPEALAGGGLGAASYSFVSIfcvGVIAAVGTlvAIRHGAGDIEGAT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 119 KLSMLGVYLqrSWVILNVTAVILSLLyifaAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVM 198
Cdd:PRK00187 87 RLAQAGLWL--AWLLALVAALLLWNL----KPLLLLFGQAPQNVDAAMQFLHLLPFALPGYLSFMALRGFTSALGRAGPV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 199 AAISAVALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSGTCGEAW---SGFSWEAFHNLWSFVR 271
Cdd:PRK00187 161 MVISLAGAVANLLLNYALIEGWfglpKLGLMGIGLVTALVSNGMALALALYIRRHPAYAAYplrKGLSRPSRAALRELWR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 272 LSLASAVMLCLEVWYLMAVILFAGYLKNAEIsvAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVA 351
Cdd:PRK00187 241 LGLPIGGTYAVEVGLFTFAALCMGALGSTQL--AAHQIALQIVSVAFMVPVGLSYAVTMRVGQHYGAGRLLEARRAGRVG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 352 VITSTVIGLAISIALLIFRDKYPSLFV-----GDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIV 426
Cdd:PRK00187 319 IGFGAVVMLLFAGLFWLLPEAIIGLFLdrndpAFAEIVQLAVSLLAVAAWFELFDGTQTIAMGAIRGLKDARTTFLIGLA 398
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 75180368 427 CYYVFGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTW 467
Cdd:PRK00187 399 CYWLVGAPLAWLLAFTLGWGAVGVWWGLALGLACAAVALTL 439
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
73-471 |
2.32e-10 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 62.62 E-value: 2.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 73 FAGHISTIALAAVSVENSV---IAGFSFGvmlgMGSALETLCGQAFGAGKLSMLGVYLQRSWVILNVTAVILSLLYIFAA 149
Cdd:cd13145 35 FAGKISTEALAALSLSFPIffiIIAIGVG----IGTGTTALIGNALGAGDRRKARRYAAQGLSFGIILAILLTVIGLFAA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 150 P-ILAFIGQTPAISSATgifSIYMIPQIFA---YAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLT-WFVIEGLQW-- 222
Cdd:cd13145 111 PpLFRLLGAEGDYLDLA---LEYMDVIFAGsifFLLNFGLNGILNAQGDTKSYRNFLIIGFFLNIILDpLFIFGGGGIpa 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 223 -GTAGLAVVLNASwWFIVVAQLVYIFSGTcgEAWSGFSWEAFHNLWSFVRLSLASAVMLCLEvwylMAVILFAGYL---- 297
Cdd:cd13145 188 mGVSGIALATIIS-QFIGMFYLLYKVRKS--GIISGCRLRDFIPRLDVYKEILKQGFPASLN----MMTIGLGIFVityf 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 298 --KNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKH----PRTAKFSLLVAVITSTVIGlaisIALLIFRD 371
Cdd:cd13145 261 vgQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKydrvRETYKKALKYGFVIMVVAT----VFLLFFAE 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 372 KYPSLFVGDEEVIIVVKDLtpiLAVSIVINNVQPVL-SGVAVGAGWQ--AVVAYVNIVCYYVFGIPFGLLLGYKLNFGVM 448
Cdd:cd13145 337 PLMSLFTNDPAVIAIGAGY---LRIDALIFYAYVVLfISVSVLQGLKrpIFALWIGLYRQLVGPALVFWLLVNVLGLGVT 413
|
410 420
....*....|....*....|...
gi 75180368 449 GIWCGMLTGTVVQTIVLTWMICR 471
Cdd:cd13145 414 GIWWGIFTIVWSAAIIALLYTRR 436
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
269-471 |
9.18e-09 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 57.46 E-value: 9.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 269 FVRLSLASAVMLCLEVWYLMAVILFAGYLknAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSL 348
Cdd:COG0534 10 LLRLALPIILGNLLQSLYGLVDTIFVGRL--GTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARRVL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 349 LVAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCY 428
Cdd:COG0534 88 GQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLIGN 167
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 75180368 429 yVFGIPFGLLLGYKLNFGVMGIWCGMLTGTVVQTIVLTWMICR 471
Cdd:COG0534 168 -VLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFR 209
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
56-247 |
4.63e-08 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 55.02 E-value: 4.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 56 AIFMSITQYSLGAATQVFAGHISTIALAAVSVENSvIAGFSFGVMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVILN 135
Cdd:cd12082 229 AIQNSLLSLGLLIIVAIVAAFGGAAALAAYTVAFR-IASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 136 VTAVILSLL-YIFAAPILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLTW 214
Cdd:cd12082 308 LIGAVLGLLiLLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLA 387
|
170 180 190
....*....|....*....|....*....|...
gi 75180368 215 FVIEGLQWGTAGLAVVLNASWWFIVVAQLVYIF 247
Cdd:cd12082 388 YVLAYLGLGLYGIWLALVISLILAALVLLLFFR 420
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
47-451 |
1.72e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 50.31 E-value: 1.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 47 KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVS----VENSVIAgfsfgVMLGMGSALETLCGQAFGAGKLSM 122
Cdd:cd13144 8 RLLLTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSlafpIQNLMIA-----VAVGTGVGVNALLSRSLGEKDQKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 123 LGVYLQRSWVILNVTAVILSLLYIFAA-PILAFIGQTPAISSATGIFSIYMIPQIFAYAVNYPTAKFLQSQSKIMVMAAI 201
Cdd:cd13144 83 ANKAANNGLLLALLSYLLFLLLGLFGVkPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 202 SAVALVLHVLLTWFVIEGL----QWGTAGLAVVLNASWwfIVVAQLVYIFSGTCGEAwSGFSWEAFHNLWSFVR----LS 273
Cdd:cd13144 163 QLIGAIINIILDPILIFGLfgfpAMGIAGAAIATVIGQ--ILAMFLAFFFLLRKNKD-VQPDLRLFRPSLRIIKeiyaVG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 274 LASAVMLCLEVW--YLMAVILFAgylkNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVA 351
Cdd:cd13144 240 LPSIIMQAISSVmvFGLNKILAG----FGPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGNKDRIREAIKYA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 352 VITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVF 431
Cdd:cd13144 316 ILIAVVIMLAGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVV 395
|
410 420
....*....|....*....|
gi 75180368 432 GIPFGLLLGYKlnFGVMGIW 451
Cdd:cd13144 396 LLPLAWLLAKM--FGLNGVW 413
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
34-155 |
4.58e-04 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 42.23 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 34 TVGGFVKEFNVEVKKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAgFSFGVMLGMGSALETLCGQ 113
Cdd:TIGR00797 203 KWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFALLALLVARLGSIALAAHQIALNVES-LLFMPAFGFGIAVSILVGQ 281
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 75180368 114 AFGAGKLSMLGVYLQRSWVILNVTAVILSLLYIFAAPILAFI 155
Cdd:TIGR00797 282 ALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFREFIARL 323
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
52-415 |
5.62e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 39.18 E-value: 5.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 52 LAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVensVIAGFSFGVML---GMGSALETLCGQAFGAGKLSMLGVYLQ 128
Cdd:cd13148 17 LALPNILALLVQTLVGLAETYFVGQLGTDALAGVAL---VFPLLMLTQMMsngAMGGGVSSAIARALGAGDRERAEALVW 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 129 RSWVILNVTAVILSLLY-IFAAPILAFIGQTPAISSATGIFSIYMIP-QIFAYAVNYpTAKFLQSQSKIMVMAAISAVAL 206
Cdd:cd13148 94 HALVIALAGGLVFSLLFlLFGPALYRLLGGRGEALDAALAYSNVLFSgAILIWLVNL-LAAALRGTGNMRVPALVTLVGA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 207 VLHVLLTWFVIEGL----QWGTAGLAVVLNASWWFIVVAQLVYIFSG----TCGEAWSGFSWEAFHNLWSFVRLSLASAV 278
Cdd:cd13148 173 VVQIPLSPGLILGWgplpRLGVAGAAVAAVLYYALAALVLLRYLASGrsrlRLRLRALRLERRLFRDILRVGLLAALSPL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75180368 279 MLCLEVWYLMAVILFAGylknaEISVAALSICMNILGWTAMIAIGMNAAVSVRVSNELGAKHPRTAKFSLLVAVITSTVI 358
Cdd:cd13148 253 QTNLTVLLLTGLVGRFG-----TAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIAWTGALMAAVL 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 75180368 359 GLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTPILAVSIVINNVQPVLSGVAVGAG 415
Cdd:cd13148 328 AGAIGLVLALFPELWLGLFTHDPAVLAAGASYLRIVGPFYGFFGLGLALYFASQGAG 384
|
|
| |
