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Conserved domains on  [gi|75163801|sp|Q93ZN9|]
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RecName: Full=LL-diaminopimelate aminotransferase, chloroplastic; Short=AtDAP-AT; Short=DAP-AT; Short=DAP-aminotransferase; Short=LL-DAP-aminotransferase; AltName: Full=Protein ABERRANT GROWTH AND DEATH 2; Flags: Precursor

Protein Classification

DAPAT_plant superfamily protein( domain architecture ID 1014921)

DAPAT_plant superfamily protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DAPAT_plant super family cl30202
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ...
59-458 3.39e-177

LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).


The actual alignment was detected with superfamily member TIGR03542:

Pssm-ID: 163316  Cd Length: 402  Bit Score: 501.95  E-value: 3.39e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPL 138
Cdd:TIGR03542   1 MKRNPHFLKLKSSYLFSEINKRVAEFRKKNPSADIIRLGIGDTTQPLPASVIEAFHNAVDELASPETFRGYGPEQGYPFL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   139 RAAIAKTFYGGLgIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNtDVQKYGNIEYMRC 218
Cdd:TIGR03542  81 REAIAENDYRGR-IDPEEIFISDGAKCDVFRLQSLFGPDNTVAVQDPVYPAYLDSNVMAGRAGVLD-DDGRYSKITYLPC 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVA 297
Cdd:TIGR03542 159 TAENNFIPELPEEPHIDIIYLCSPNNPTGTVLTKEQLKELVDYANEHGSLILFDAAYSAFISDPSlPHSIFEIPGARFCA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENT 377
Cdd:TIGR03542 239 IEFRSFSKTAGFTGVRLGWTVVPKELTYADGHSVIQDWERRQCTKFNGASYPVQRAAEAGYAGEGLQPILEAISYYMENA 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   378 NIIIDTFTSLGYDVYGGKNAPYVWVHFP-NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRF 456
Cdd:TIGR03542 319 RILRKALEAAGFKVYGGEHAPYLWVKTPeGISSWDFFDFLLYEYHVVGTPGSGFGPSGEGFVRFSAFGKRENIIEACERI 398

                  ..
gi 75163801   457 KQ 458
Cdd:TIGR03542 399 KE 400
 
Name Accession Description Interval E-value
DAPAT_plant TIGR03542
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ...
59-458 3.39e-177

LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).


Pssm-ID: 163316  Cd Length: 402  Bit Score: 501.95  E-value: 3.39e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPL 138
Cdd:TIGR03542   1 MKRNPHFLKLKSSYLFSEINKRVAEFRKKNPSADIIRLGIGDTTQPLPASVIEAFHNAVDELASPETFRGYGPEQGYPFL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   139 RAAIAKTFYGGLgIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNtDVQKYGNIEYMRC 218
Cdd:TIGR03542  81 REAIAENDYRGR-IDPEEIFISDGAKCDVFRLQSLFGPDNTVAVQDPVYPAYLDSNVMAGRAGVLD-DDGRYSKITYLPC 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVA 297
Cdd:TIGR03542 159 TAENNFIPELPEEPHIDIIYLCSPNNPTGTVLTKEQLKELVDYANEHGSLILFDAAYSAFISDPSlPHSIFEIPGARFCA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENT 377
Cdd:TIGR03542 239 IEFRSFSKTAGFTGVRLGWTVVPKELTYADGHSVIQDWERRQCTKFNGASYPVQRAAEAGYAGEGLQPILEAISYYMENA 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   378 NIIIDTFTSLGYDVYGGKNAPYVWVHFP-NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRF 456
Cdd:TIGR03542 319 RILRKALEAAGFKVYGGEHAPYLWVKTPeGISSWDFFDFLLYEYHVVGTPGSGFGPSGEGFVRFSAFGKRENIIEACERI 398

                  ..
gi 75163801   457 KQ 458
Cdd:TIGR03542 399 KE 400
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
94-458 3.55e-72

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 231.46  E-value: 3.55e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  94 ISLGIGDTTEPIPEVITSAMAKKAHElstiEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRL- 170
Cdd:cd00609   1 IDLSIGEPDFPPPPEVLEALAAAALR----AGLLGYYPDPGLPELREAIAEWLgrRGGVDVPPEEIVVTNGAQEALSLLl 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNP 245
Cdd:cd00609  77 RALLNPGDEVLVPDPTYPGYEAAARLAG------------AEVVPVPLDEEGGFLLDLELLeaaktPKTKLLYLNNPNNP 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 246 TGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLly 325
Cdd:cd00609 145 TGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEE-- 222
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 326 sdgfpVAKDFNRIICTCFNGASNISQAGALACLTpEGLEAMHKVIGFYKENTNIIIDTFTSLGYDV-YGGKNAPYVWVHF 404
Cdd:cd00609 223 -----LLERLKKLLPYTTSGPSTLSQAAAAAALD-DGEEHLEELRERYRRRRDALLEALKELGPLVvVKPSGGFFLWLDL 296
                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....
gi 75163801 405 PNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458
Cdd:cd00609 297 PEGDDEEFLERLLLEAGVVVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
62-459 1.52e-63

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 210.37  E-value: 1.52e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  62 NSNMSKLQAgYLFPEIARRRSAhlLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHElstieGYSGYGAEQGAKPLRAA 141
Cdd:COG0436   4 SSRLARLPP-SPIREVSALAAE--LKAAGEDVIDLGIGEPDFPTPDHIREAAIEALDD-----GVTGYTPSAGIPELREA 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 142 IA---KTFYGgLGIGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMR 217
Cdd:COG0436  76 IAayyKRRYG-VDLDPDEILVTNGAKEALALaLLALLNPGDEVLVPDPGYPSYRAAVRLAG------------GKPVPVP 142
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 218 CTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIP 291
Cdd:COG0436 143 LDEENGFLPDPEALeaaitPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAeHVSILSLP 222
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 292 GAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLysdgfpvaKDFNRIICTCFNGASNISQAGALACLTpEGLEAMHKVIG 371
Cdd:COG0436 223 GLKDRTIVINSFSKSYAMTGWRIGYAVGPPELI--------AALLKLQSNLTSCAPTPAQYAAAAALE-GPQDYVEEMRA 293
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 372 FYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP--NQSSWDvFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN 448
Cdd:COG0436 294 EYRRRRDLLVEGLNEIGLSVVKPEGAFYLFADVPelGLDSEE-FAErLLEEAGVAVVPGSAFGPAGEGYVRISYATSEER 372
                       410
                ....*....|.
gi 75163801 449 ILEACRRFKQL 459
Cdd:COG0436 373 LEEALERLARF 383
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
72-459 4.88e-49

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 172.02  E-value: 4.88e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   72 YLFPEIARRRSAHLLKYPDaqVISLGIGDTTEPIPEVITSAMAKKAHELSTiEGYSGYgaeQGAKPLRAAIAKTFYGGLG 151
Cdd:PRK09276  14 YLFAEIDKKKAEKIARGVD--VISLGIGDPDLPTPDHIIEAMCKAVEDPEN-HQYPSY---EGMLEFRKAVADWYKRRFG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  152 IG---DDDVFVSDGAKCDISRLQVMF---GsNVTIaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFF 225
Cdd:PRK09276  88 VEldpETEVISLIGSKEGIAHIPLAFvnpG-DVVL-VPDPGYPVYKIGTIFAG------------GEPYFMPLKEENGFL 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  226 PDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAME 299
Cdd:PRK09276 154 PDLDAIpedvaKKAKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSeIAYDGYKPPSFLEVPGAKDVGIE 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  300 TASFSKYAGFTGVRLGWTVIPKKLLysDGFPVAKdfnriictcfngaSN--------ISQAGALACLTPE-GLEAMHKVi 370
Cdd:PRK09276 234 FHSLSKTYNMTGWRIGFAVGNADLI--AGLGKVK-------------SNvdsgvfqaIQEAGIAALNGPQeVVEELRKI- 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  371 gfYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENI 449
Cdd:PRK09276 298 --YQERRDILVEGLRKLGLEVEPPKATFYVWAPVPKGYTSAEFATlLLDKAGVVVTPGNGFGEYGEGYFRIALTVPDERI 375
                        410
                 ....*....|
gi 75163801  450 LEACRRFKQL 459
Cdd:PRK09276 376 EEAVERIKKL 385
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
93-456 1.46e-33

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 129.35  E-value: 1.46e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    93 VISLGIGD-TTEPIPEVItsamaKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG---DDDVFVSDGAKCDIS 168
Cdd:pfam00155   3 KINLGSNEyLGDTLPAVA-----KAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKldrEAAVVFGSGAGANIE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   169 RL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSP 242
Cdd:pfam00155  78 ALiFLLANPGDAILVPAPTYASYIRIARLAG------------GEVVRYPLYDSNDFHLDFDALeaalkEKPKVVLHTSP 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA--MYMSDDNPRSIFEIPGAEEVAmETASFSKYAGFTGVRLGWTVIP 320
Cdd:pfam00155 146 HNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAgfVFGSPDAVATRALLAEGPNLL-VVGSFSKAFGLAGWRVGYILGN 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   321 KKLLYSdgfpvAKDFNRIICTcfngaSNISQAGALACL--TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP 398
Cdd:pfam00155 225 AAVISQ-----LRKLARPFYS-----STHLQAAAAAALsdPLLVASELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGF 294
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801   399 YVWVHFPNQSSWDVFAEILEKTHVVTTpgSGFGPGGEGFVRVSAFGH-RENILEACRRF 456
Cdd:pfam00155 295 FLLTGLDPETAKELAQVLLEEVGVYVT--PGSSPGVPGWLRITVAGGtEEELEELLEAI 351
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
94-459 1.79e-33

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 129.38  E-value: 1.79e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIGDTTEPIPEVITSAMAKKAHELstiEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG--DDDVFVSDGAKCDI---S 168
Cdd:NF041364   1 YNLGEGGPDFPTPEHVLEATKDALELL---PGSLHYTPNSGSLELREAIAALYKDGYGIEvsPDQVLVTTGASEALflyF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMFGSNVTiaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPEN-GFFPDLSTV-----GRTDIIFFCSP 242
Cdd:NF041364  78 HALLEPGDEVV--VPVPAFQSLYEVPELLG------------GRVRPLPLSPENqGFRPDLEALrslitPRTRAIVINSP 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321
Cdd:NF041364 144 NNPTGAVMTEAELEAILEIASRHGLIVLADEHYRFLPYDDGkHVSPSLYPGLSERVIALGSFSKTYGMTGLRVGWLIGPK 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  322 KLLysDGFPVAKDFNrIICTCfngasNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVW 401
Cdd:NF041364 224 ELI--GAILKFKDYT-THCAP-----SISQYAALEALEQGPQERVKGWVRENVRRRDALVERLERLIGWVCEPEGGFYAF 295
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801  402 VHFPNQSSWDVFAEIL-EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459
Cdd:NF041364 296 PKLKDGLPSAAFAEELlEKAGVVVLPGSAFGRPGEGYFRIGFANSPTRLKEALERLSRF 354
 
Name Accession Description Interval E-value
DAPAT_plant TIGR03542
LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of ...
59-458 3.39e-177

LL-diaminopimelate aminotransferase; This clade of the pfam00155 superfamily of aminotransferases includes several which are adjacent to elements of the lysine biosynthesis via diaminopimelate pathway (GenProp0125). This clade includes characterized species in plants and Chlamydia. Every member of this clade is from a genome which possesses most of the lysine biosynthesis pathway but lacks any of the known succinylases, desuccinylases, acetylases or deacetylases typical of the acylated versions of this pathway nor do they have the direct, NADPH-dependent enzyme (ddh).


Pssm-ID: 163316  Cd Length: 402  Bit Score: 501.95  E-value: 3.39e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    59 VSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPL 138
Cdd:TIGR03542   1 MKRNPHFLKLKSSYLFSEINKRVAEFRKKNPSADIIRLGIGDTTQPLPASVIEAFHNAVDELASPETFRGYGPEQGYPFL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   139 RAAIAKTFYGGLgIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNtDVQKYGNIEYMRC 218
Cdd:TIGR03542  81 REAIAENDYRGR-IDPEEIFISDGAKCDVFRLQSLFGPDNTVAVQDPVYPAYLDSNVMAGRAGVLD-DDGRYSKITYLPC 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   219 TPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVA 297
Cdd:TIGR03542 159 TAENNFIPELPEEPHIDIIYLCSPNNPTGTVLTKEQLKELVDYANEHGSLILFDAAYSAFISDPSlPHSIFEIPGARFCA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   298 METASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENT 377
Cdd:TIGR03542 239 IEFRSFSKTAGFTGVRLGWTVVPKELTYADGHSVIQDWERRQCTKFNGASYPVQRAAEAGYAGEGLQPILEAISYYMENA 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   378 NIIIDTFTSLGYDVYGGKNAPYVWVHFP-NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRF 456
Cdd:TIGR03542 319 RILRKALEAAGFKVYGGEHAPYLWVKTPeGISSWDFFDFLLYEYHVVGTPGSGFGPSGEGFVRFSAFGKRENIIEACERI 398

                  ..
gi 75163801   457 KQ 458
Cdd:TIGR03542 399 KE 400
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
94-458 3.55e-72

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 231.46  E-value: 3.55e-72
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  94 ISLGIGDTTEPIPEVITSAMAKKAHElstiEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVSDGAKCDISRL- 170
Cdd:cd00609   1 IDLSIGEPDFPPPPEVLEALAAAALR----AGLLGYYPDPGLPELREAIAEWLgrRGGVDVPPEEIVVTNGAQEALSLLl 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 171 QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNP 245
Cdd:cd00609  77 RALLNPGDEVLVPDPTYPGYEAAARLAG------------AEVVPVPLDEEGGFLLDLELLeaaktPKTKLLYLNNPNNP 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 246 TGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLly 325
Cdd:cd00609 145 TGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEE-- 222
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 326 sdgfpVAKDFNRIICTCFNGASNISQAGALACLTpEGLEAMHKVIGFYKENTNIIIDTFTSLGYDV-YGGKNAPYVWVHF 404
Cdd:cd00609 223 -----LLERLKKLLPYTTSGPSTLSQAAAAAALD-DGEEHLEELRERYRRRRDALLEALKELGPLVvVKPSGGFFLWLDL 296
                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....
gi 75163801 405 PNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458
Cdd:cd00609 297 PEGDDEEFLERLLLEAGVVVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
62-459 1.52e-63

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 210.37  E-value: 1.52e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  62 NSNMSKLQAgYLFPEIARRRSAhlLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHElstieGYSGYGAEQGAKPLRAA 141
Cdd:COG0436   4 SSRLARLPP-SPIREVSALAAE--LKAAGEDVIDLGIGEPDFPTPDHIREAAIEALDD-----GVTGYTPSAGIPELREA 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 142 IA---KTFYGgLGIGDDDVFVSDGAKCDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMR 217
Cdd:COG0436  76 IAayyKRRYG-VDLDPDEILVTNGAKEALALaLLALLNPGDEVLVPDPGYPSYRAAVRLAG------------GKPVPVP 142
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 218 CTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIP 291
Cdd:COG0436 143 LDEENGFLPDPEALeaaitPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAeHVSILSLP 222
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 292 GAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLysdgfpvaKDFNRIICTCFNGASNISQAGALACLTpEGLEAMHKVIG 371
Cdd:COG0436 223 GLKDRTIVINSFSKSYAMTGWRIGYAVGPPELI--------AALLKLQSNLTSCAPTPAQYAAAAALE-GPQDYVEEMRA 293
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 372 FYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP--NQSSWDvFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHREN 448
Cdd:COG0436 294 EYRRRRDLLVEGLNEIGLSVVKPEGAFYLFADVPelGLDSEE-FAErLLEEAGVAVVPGSAFGPAGEGYVRISYATSEER 372
                       410
                ....*....|.
gi 75163801 449 ILEACRRFKQL 459
Cdd:COG0436 373 LEEALERLARF 383
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
72-459 4.88e-49

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 172.02  E-value: 4.88e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   72 YLFPEIARRRSAHLLKYPDaqVISLGIGDTTEPIPEVITSAMAKKAHELSTiEGYSGYgaeQGAKPLRAAIAKTFYGGLG 151
Cdd:PRK09276  14 YLFAEIDKKKAEKIARGVD--VISLGIGDPDLPTPDHIIEAMCKAVEDPEN-HQYPSY---EGMLEFRKAVADWYKRRFG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  152 IG---DDDVFVSDGAKCDISRLQVMF---GsNVTIaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFF 225
Cdd:PRK09276  88 VEldpETEVISLIGSKEGIAHIPLAFvnpG-DVVL-VPDPGYPVYKIGTIFAG------------GEPYFMPLKEENGFL 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  226 PDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAME 299
Cdd:PRK09276 154 PDLDAIpedvaKKAKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSeIAYDGYKPPSFLEVPGAKDVGIE 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  300 TASFSKYAGFTGVRLGWTVIPKKLLysDGFPVAKdfnriictcfngaSN--------ISQAGALACLTPE-GLEAMHKVi 370
Cdd:PRK09276 234 FHSLSKTYNMTGWRIGFAVGNADLI--AGLGKVK-------------SNvdsgvfqaIQEAGIAALNGPQeVVEELRKI- 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  371 gfYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENI 449
Cdd:PRK09276 298 --YQERRDILVEGLRKLGLEVEPPKATFYVWAPVPKGYTSAEFATlLLDKAGVVVTPGNGFGEYGEGYFRIALTVPDERI 375
                        410
                 ....*....|
gi 75163801  450 LEACRRFKQL 459
Cdd:PRK09276 376 EEAVERIKKL 385
PRK08068 PRK08068
transaminase; Reviewed
91-459 1.96e-37

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 140.83  E-value: 1.96e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   91 AQVISLGIGDTTEPIPEVITSAMAKKAHELStiegYSGYGAEQGAKPLRAAIAKtFYG---GLGIG-DDDVFVSDGAKCD 166
Cdd:PRK08068  32 HDVINLGQGNPDQPTPEHIVEALQEAAENPA----NHKYSPFRGYPFLKEAAAD-FYKreyGVTLDpETEVAILFGGKAG 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  167 ISRL-QVMFGSNVTIAVQDPSYPAYVdSSVIMGQtgqfntdvqkyGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFC 240
Cdd:PRK08068 107 LVELpQCLMNPGDTILVPDPGYPDYL-SGVALAR-----------AQFETMPLIAENNFLPDYTKIPeevaeKAKLMYLN 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY-AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319
Cdd:PRK08068 175 YPNNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYgAIGFDGQKPVSFLQTPGAKDVGIELYTLSKTFNMAGWRVAFAVG 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  320 PKKL-----LYSDgfpvakdfnRIICTCFNGasnISQAGALACLTPEglEAMHKVIGFYKENTNIIIDTFTSLGYDVYGG 394
Cdd:PRK08068 255 NESVieainLLQD---------HLFVSLFGA---IQDAAIEALLSDQ--SCVAELVARYESRRNAFISACREIGWEVDAP 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75163801  395 KNAPYVWVHFPNQSSWDVFAEIL-EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459
Cdd:PRK08068 321 KGSFFAWMPVPKGYTSEQFADLLlEKAHVAVAPGNGFGEHGEGYVRVGLLTDEERLREAVERIGKL 386
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
63-405 5.33e-36

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 137.48  E-value: 5.33e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   63 SNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTiEGYsgygAEQGAKPLRAAI 142
Cdd:PRK06290  16 KNFGKETVIYKFEKIKRAKRAAKEKHPDMELIDMGVGEPDEMADESVVEVLCEEAKKPEN-RGY----ADNGIQEFKEAA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  143 A---KTFYGGLGIG-DDDVFVSDGAKCDISRLQVMF--GSNVTIAVQdPSYPayvdssvIMGqtgqfnTDVQKY-GNIEY 215
Cdd:PRK06290  91 ArymEKVFGVKDIDpVTEVIHSIGSKPALAMLPSCFinPGDVTLMTV-PGYP-------VTG------THTKYYgGEVYN 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  216 MRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 290
Cdd:PRK06290 157 LPLLEENNFLPDLDSIpkdikEKAKLLYLNYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDGKPLSFLSV 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  291 PGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLysDGFPVAKDfnriictcfNGASN----ISQAGAlACLtpEGLEAM 366
Cdd:PRK06290 237 PGAKEVGVEIHSLSKAYNMTGWRLAFVVGNELIV--KAFATVKD---------NNDSGqfiaIQKAGI-YAL--DHPEIT 302
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 75163801  367 HKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFP 405
Cdd:PRK06290 303 EKIREKYSRRLDKLVKILNEVGFKAEMPGGTFYLYVKAP 341
PRK05764 PRK05764
aspartate aminotransferase; Provisional
93-458 1.13e-35

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 136.02  E-value: 1.13e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGdttEP---IPEVITSAmAKKAHElstiEGYSGYGAEQGAKPLRAAIAKTFY--GGLGIGDDDVFVSDGAKcdi 167
Cdd:PRK05764  33 VISLGAG---EPdfdTPEHIKEA-AIEALD----DGKTKYTPAAGIPELREAIAAKLKrdNGLDYDPSQVIVTTGAK--- 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  168 srlQVMF---------GSNVTIAvqDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GR 233
Cdd:PRK05764 102 ---QALYnafmalldpGDEVIIP--APYWVSYPEMVKLAG------------GVPVFVPTGEENGFKLTVEQLeaaitPK 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIvydsayamyMSDDnprsIFE---IPGAEEVAMETAS-------- 302
Cdd:PRK05764 165 TKALILNSPSNPTGAVYSPEELEAIADVAVEHDIWV---------LSDE----IYEklvYDGAEFTSIASLSpelrdrti 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  303 ----FSKYAGFTGVRLGWTVIPKkllysdgfPVAKDFNRIICTCFNGASNISQAGALACLTP--EGLEAMHKVigfYKEN 376
Cdd:PRK05764 232 tvngFSKAYAMTGWRLGYAAGPK--------ELIKAMSKLQSHSTSNPTSIAQYAAVAALNGpqDEVEEMRQA---FEER 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  377 TNIIIDTFTSL-GYDVYGGKNAPYVWV---HFPNQSSWDV--FAE-ILEKTHVVTTPGsgfgpggegfvrvSAFGHR--- 446
Cdd:PRK05764 301 RDLMVDGLNEIpGLECPKPEGAFYVFPnvsKLLGKSITDSleFAEaLLEEAGVAVVPG-------------IAFGAPgyv 367
                        410       420
                 ....*....|....*....|
gi 75163801  447 --------ENILEACRRFKQ 458
Cdd:PRK05764 368 rlsyatslEDLEEGLERIER 387
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
93-456 1.46e-33

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 129.35  E-value: 1.46e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    93 VISLGIGD-TTEPIPEVItsamaKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG---DDDVFVSDGAKCDIS 168
Cdd:pfam00155   3 KINLGSNEyLGDTLPAVA-----KAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKldrEAAVVFGSGAGANIE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   169 RL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSP 242
Cdd:pfam00155  78 ALiFLLANPGDAILVPAPTYASYIRIARLAG------------GEVVRYPLYDSNDFHLDFDALeaalkEKPKVVLHTSP 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA--MYMSDDNPRSIFEIPGAEEVAmETASFSKYAGFTGVRLGWTVIP 320
Cdd:pfam00155 146 HNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAgfVFGSPDAVATRALLAEGPNLL-VVGSFSKAFGLAGWRVGYILGN 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   321 KKLLYSdgfpvAKDFNRIICTcfngaSNISQAGALACL--TPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAP 398
Cdd:pfam00155 225 AAVISQ-----LRKLARPFYS-----STHLQAAAAAALsdPLLVASELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGF 294
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801   399 YVWVHFPNQSSWDVFAEILEKTHVVTTpgSGFGPGGEGFVRVSAFGH-RENILEACRRF 456
Cdd:pfam00155 295 FLLTGLDPETAKELAQVLLEEVGVYVT--PGSSPGVPGWLRITVAGGtEEELEELLEAI 351
GntC_guanitoxin NF041364
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
94-459 1.79e-33

guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;


Pssm-ID: 469255  Cd Length: 354  Bit Score: 129.38  E-value: 1.79e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIGDTTEPIPEVITSAMAKKAHELstiEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG--DDDVFVSDGAKCDI---S 168
Cdd:NF041364   1 YNLGEGGPDFPTPEHVLEATKDALELL---PGSLHYTPNSGSLELREAIAALYKDGYGIEvsPDQVLVTTGASEALflyF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMFGSNVTiaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPEN-GFFPDLSTV-----GRTDIIFFCSP 242
Cdd:NF041364  78 HALLEPGDEVV--VPVPAFQSLYEVPELLG------------GRVRPLPLSPENqGFRPDLEALrslitPRTRAIVINSP 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321
Cdd:NF041364 144 NNPTGAVMTEAELEAILEIASRHGLIVLADEHYRFLPYDDGkHVSPSLYPGLSERVIALGSFSKTYGMTGLRVGWLIGPK 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  322 KLLysDGFPVAKDFNrIICTCfngasNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVW 401
Cdd:NF041364 224 ELI--GAILKFKDYT-THCAP-----SISQYAALEALEQGPQERVKGWVRENVRRRDALVERLERLIGWVCEPEGGFYAF 295
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801  402 VHFPNQSSWDVFAEIL-EKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQL 459
Cdd:NF041364 296 PKLKDGLPSAAFAEELlEKAGVVVLPGSAFGRPGEGYFRIGFANSPTRLKEALERLSRF 354
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
65-458 1.12e-26

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 111.05  E-value: 1.12e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   65 MSKLQAGyLFPEIARRRSAHllKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHElstIEGYsGYgAEQGAKPLRAAIAK 144
Cdd:PRK07681   9 MKAFQSS-IFSELGAYKKEK--IAAGHKMIDLSIGNPDMPPADFVREEMVHTANQ---KESY-GY-TLSGIQEFHEAVTE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  145 TFYGGLGI---GDDDVFVSDGAKCDISRLQVMFGS-NVTIAVQDPSYPAYVDSSVIMGQTgqfntdvqkygnIEYMRCTP 220
Cdd:PRK07681  81 YYNNTHNVilnADKEVLLLMGSQDGLVHLPMVYANpGDIILVPDPGYTAYETGIQMAGAT------------SYYMPLKK 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  221 ENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAE 294
Cdd:PRK07681 149 ENDFLPDLELIpeeiaDKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNkPISFLSVPGAK 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  295 EVAMETASFSKYAGFTGVRLGW-----------TVIPKKLLYSDGFPVAKdfnriictcfnGASNISQAGALACLTPEGL 363
Cdd:PRK07681 229 EVGVEINSLSKSYSLAGSRIGYmigneeivralTQFKSNTDYGVFLPIQK-----------AACAALRNGAAFCEKNRGI 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  364 eamhkvigfYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPN-QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSA 442
Cdd:PRK07681 298 ---------YQERRDTLVDGFRTFGWNVDKPAGSMFVWAEIPKgWTSLSFAYALMDRANVVVTPGHAFGPHGEGFVRIAL 368
                        410
                 ....*....|....*.
gi 75163801  443 FGHRENILEACRRFKQ 458
Cdd:PRK07681 369 VQDEEVLQQAVENIRN 384
PRK05942 PRK05942
aspartate aminotransferase; Provisional
93-458 1.28e-26

aspartate aminotransferase; Provisional


Pssm-ID: 180317  Cd Length: 394  Bit Score: 110.96  E-value: 1.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTEPIPE-VITSAMAKKAHElstieGYSGYGAEQGAKPLRAAIAKTF---YGGLGIGDDDVFVSDGAKCDIS 168
Cdd:PRK05942  37 LIDLGMGNPDGAAPQpVIEAAIAALADP-----QNHGYPPFEGTASFRQAITDWYhrrYGVELDPDSEALPLLGSKEGLT 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMF-GSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSP 242
Cdd:PRK05942 112 HLALAYvNPGDVVLVPSPAYPAHFRGPLIAG------------AQIYPIILKPENDWLIDLSSIpeevaQQAKILYFNYP 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321
Cdd:PRK05942 180 SNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGyQPTSLLEIPGAKDIGVEFHTLSKTYNMAGWRVGFVVGNR 259
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  322 KLLYSdgfpvakdfNRIICTCFN-GASNISQAGALACLT-PEglEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPY 399
Cdd:PRK05942 260 HIIQG---------LRTLKTNLDyGIFSALQKAAETALQlPD--SYLQQVQERYRTRRDFLIQGLGELGWNIPPTKATMY 328
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  400 VWVHFP-NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458
Cdd:PRK05942 329 LWVPCPvGMGSTDFALNVLQKTGVVVTPGNAFGEGGEGYVRISLIADCDRLGEALDRLKQ 388
PRK07682 PRK07682
aminotransferase;
93-423 5.13e-26

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 108.67  E-value: 5.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDttepiPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIG---DDDVFVSDGAK--CDI 167
Cdd:PRK07682  22 VISLGVGE-----PDFVTPWNVREASIRSLEQGYTSYTANAGLLELRQEIAKYLKKRFAVSydpNDEIIVTVGASqaLDV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  168 S-RLQVMFGSNVTIAvqDPSYPAYvDSSVIMgqTGQFNTDVQKYGNIEYmRCTPEngffpDLSTV--GRTDIIFFCSPNN 244
Cdd:PRK07682  97 AmRAIINPGDEVLIV--EPSFVSY-APLVTL--AGGVPVPVATTLENEF-KVQPA-----QIEAAitAKTKAILLCSPNN 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  245 PTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324
Cdd:PRK07682 166 PTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDEAYTSFASIKGMRERTILISGFSKGFAMTGWRLGFIAAPVYFS 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  325 --------YSdgfpvakdfnrIICtcfngASNISQAGALACLTpEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKN 396
Cdd:PRK07682 246 eamlkihqYS-----------MMC-----APTMAQFAALEALR-AGNDDVIRMRDSYRKRRNFFVTSFNEIGLTCHVPGG 308
                        330       340       350
                 ....*....|....*....|....*....|....
gi 75163801  397 APYVwvhFPNQSSWDV----FAEIL---EKTHVV 423
Cdd:PRK07682 309 AFYA---FPSISSTGLsseeFAEQLlleEKVAVV 339
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
76-460 1.06e-24

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 105.14  E-value: 1.06e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   76 EIARrrSAHLLKYPDAQVISLGIG--DTTEPiPEVITSAMAKKAhelstiEGYSGYGAEQGAKPLRAAIA---KTFYGgL 150
Cdd:PRK07337  17 ELAK--EAQALERAGRDIIHMGIGepDFTAP-EPVVEAAARALR------RGVTQYTSALGLAPLREAIAawyARRFG-L 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  151 GIGDDDVFVSDGAKcdiSRLQ----VMFGSNVTIAVQDPSYPA---YVDSSvimgqtgqfntdvqkYGNIEYMRCTPENG 223
Cdd:PRK07337  87 DVAPERIVVTAGAS---AALLlaclALVERGDEVLMPDPSYPCnrhFVAAA---------------EGRPVLVPSGPAER 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  224 FFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIpGAEEVAM 298
Cdd:PRK07337 149 FQLTAADVEaawgeRTRGVLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSL-GDDVITI 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  299 EtaSFSKYAGFTGVRLGWTVIPKKLLysdgfPVakdFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTN 378
Cdd:PRK07337 228 N--SFSKYFNMTGWRLGWLVVPEALV-----GT---FEKLAQNLFICASALAQHAALACFEPDTLAIYERRRAEFKRRRD 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  379 IIIDTFTSLGYDV-YGGKNAPYVWV------HFPNQSSWDVFAEILEKTHVVTT-PGSGFGPGGEGFVRVSAFGHRENIL 450
Cdd:PRK07337 298 FIVPALESLGFKVpVMPDGAFYVYAdcrgvaHPAAGDSAALTQAMLHDAGVVLVpGRDFGPHAPRDYIRLSYATSMSRLE 377
                        410
                 ....*....|
gi 75163801  451 EACRRFKQLY 460
Cdd:PRK07337 378 EAVARLGKLF 387
PRK09148 PRK09148
LL-diaminopimelate aminotransferase;
72-405 6.77e-24

LL-diaminopimelate aminotransferase;


Pssm-ID: 181674 [Multi-domain]  Cd Length: 405  Bit Score: 103.22  E-value: 6.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   72 YLFPEIARRRSAhlLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTiegySGYGAEQGAKPLRAAIAKTFYGGLG 151
Cdd:PRK09148  13 YVFEQVNRLKAA--ARAAGADIIDLGMGNPDLPTPQHIVDKLCETAQDPRT----HRYSASKGIPGLRRAQAAYYARRFG 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  152 IG---DDDVFVSDGAKCDISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPD 227
Cdd:PRK09148  87 VKlnpDTQVVATLGSKEGFANMaQAITAPGDVILCPNPSYPIHAFGFIMAG------------GVIRSVPAEPDEEFFPA 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  228 LS-----TVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIPGAEEVAMETA 301
Cdd:PRK09148 155 LEravrhSIPKPIALIVNYPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSeIYFDGNPPPSVLQVPGAKDVTVEFT 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  302 SFSKYAGFTGVRLGWTVIPKKLLYSdgfpvakdFNRIICTCFNGASNISQAGALACLTPEGlEAMHKVIGFYKENTNIII 381
Cdd:PRK09148 235 SMSKTFSMAGWRMGFAVGNERLIAA--------LTRVKSYLDYGAFTPIQVAATAALNGPQ-DCIAEMRELYKKRRDVLV 305
                        330       340
                 ....*....|....*....|....
gi 75163801  382 DTFTSLGYDVYGGKNAPYVWVHFP 405
Cdd:PRK09148 306 ESFGRAGWDIPPPAASMFAWAPIP 329
PRK08361 PRK08361
aspartate aminotransferase; Provisional
93-458 1.07e-23

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 102.26  E-value: 1.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTEPIPEVITSAmAKKAHElstiEGYSGYGAEQGAKPLRAAIA---KTFYGgLGIGDDDVFVSDGA-KCDIS 168
Cdd:PRK08361  35 VISLGIGEPDFDTPKNIKEA-AKRALD----EGWTHYTPNAGIPELREAIAeyyKKFYG-VDVDVDNVIVTAGAyEATYL 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMFGSNVTIAVQDPSYPAYVDSSvimgqtgqfntdvqKYGNIEYMRC--TPENGFFPDLSTV-----GRTDIIFFCS 241
Cdd:PRK08361 109 AFESLLEEGDEVIIPDPAFVCYVEDA--------------KIAEAKPIRIplREENEFQPDPDELlelitKRTRMIVINY 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  242 PNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDnPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEG-AKHYPMIKYAPDNTILANSFSKTFAMTGWRLGFVIAPE 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  322 KllysdgfpVAKDFNRIICTCF-NGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSL-GYDVYGGKNAPY 399
Cdd:PRK08361 254 Q--------VIKDMIKLHAYIIgNVASFVQIAGIEALRSKESWKAVEEMRKEYNERRKLVLKRLKEMpHIKVFEPKGAFY 325
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75163801  400 VWvhfPNQSSWDV----FAE-ILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQ 458
Cdd:PRK08361 326 VF---ANIDETGMssedFAEwLLEKARVVVIPGTAFGKAGEGYIRISYATSKEKLIEAMERMEK 386
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
132-419 1.60e-23

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 100.98  E-value: 1.60e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 132 EQGAKPLRAAIAKTFygglGIGDDDVFVSDGAkcD--ISRL-QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvq 208
Cdd:COG0079  47 DPDATALREALAEYY----GVPPEQVLVGNGS--DelIQLLaRAFLGPGDEVLVPEPTFSEYPIAARAAG---------- 110
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 209 kygnIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVyDSAYAMYmSDDN 283
Cdd:COG0079 111 ----AEVVEVPLDEDFSLDLDALlaaitERTDLVFLCNPNNPTGTLLPREELEALLEALPADGLVVV-DEAYAEF-VPEE 184
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 284 PRSIFEIPGAEEVAMeTASFSKYAGFTGVRLGWTVIPKKLlysdgfpvAKDFNRiICTCFNgASNISQAGALACLTPEG- 362
Cdd:COG0079 185 DSALPLLARYPNLVV-LRTFSKAYGLAGLRLGYAIASPEL--------IAALRR-VRGPWN-VNSLAQAAALAALEDRAy 253
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 75163801 363 LEAMHKVIgfyKENTNIIIDTFTSLGYDVYGGKnAPYVWVHFPNQSSwDVFAEILEK 419
Cdd:COG0079 254 LEETRARL---RAERERLAAALRALGLTVYPSQ-ANFVLVRVPEDAA-ELFEALLER 305
PRK08175 PRK08175
aminotransferase; Validated
78-461 3.05e-18

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 86.30  E-value: 3.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   78 ARRRSAhllkypdaQVISLGIGDTTEPIPEVITSAMAKKAHELSTiegySGYGAEQGAKPLRAAIAKTFYGGLGIG---D 154
Cdd:PRK08175  24 ARRRGE--------DIIDFSMGNPDGPTPPHIVEKLCEVAQRPDT----HGYSTSRGIPRLRRAISRWYQDRYDVDidpE 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  155 DDVFVSDGAKCDISRLQV-MFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLS---- 229
Cdd:PRK08175  92 SEAIVTIGSKEGLAHLMLaTLDHGDTVLVPNPSYPIHIYGAVIAG------------AQVRSVPLVEGVDFFNELErair 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  230 -TVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD-NPRSIFEIPGAEEVAMETASFSKYA 307
Cdd:PRK08175 160 eSYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGwKAPSIMQVPGAKDVAVEFFTLSKSY 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  308 GFTGVRLGWTVIPKKLLYSdgfpvakdFNRIICTCFNGASNISQAGALACLtpEGLEAMHKVIG-FYKENTNIIIDTFTS 386
Cdd:PRK08175 240 NMAGWRIGFMVGNPELVSA--------LARIKSYHDYGTFTPLQVAAIAAL--EGDQQCVRDIAeQYKRRRDVLVKGLHE 309
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801  387 LGYDVYGGKNAPYVWVHFPNQ----SSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 461
Cdd:PRK08175 310 AGWMVEMPKASMYVWAKIPEPyaamGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFR 388
PRK07683 PRK07683
aminotransferase A; Validated
79-422 7.07e-18

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 85.16  E-value: 7.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   79 RRRSAHLLKYPDaqVISLGIGDTTEPIPEVITSAmAKKAhelsTIEGYSGYGAEQGAKPLRAAIA---KTFYGGLGIGDD 155
Cdd:PRK07683  18 RQFSNMVQNYDN--LISLTIGQPDFPTPSHVKEA-AKRA----ITENYTSYTHNAGLLELRKAACnfvKDKYDLHYSPES 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  156 DVFVSDGAK--CDIS-RLQVMFGSNVTIAVqdPSYPAYVDSSVIMGQTGQFnTDVQKYGnieyMRCTP---ENGFFPdls 229
Cdd:PRK07683  91 EIIVTIGASeaIDIAfRTILEPGTEVILPA--PIYPGYEPIIRLCGAKPVF-IDTRSTG----FRLTAealENAITE--- 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  230 tvgRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGF 309
Cdd:PRK07683 161 ---KTRCVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQPHTSIAHFPEMREKTIVINGLSKSHSM 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  310 TGVRLGWTVIPKkllysdgfPVAKDFNRI---ICTCfngASNISQAGALACLTP--EGLEAMHKVigfYKENTNIIIDTF 384
Cdd:PRK07683 238 TGWRIGFLFAPS--------YLAKHILKVhqyNVTC---ASSISQYAALEALTAgkDDAKMMRHQ---YKKRRDYVYNRL 303
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 75163801  385 TSLGYDVYGGKNAPYVwvhFP-----NQSSWDVFAEILEKTHV 422
Cdd:PRK07683 304 ISMGLDVEKPTGAFYL---FPsighfTMSSFDFALDLVEEAGL 343
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
72-461 7.18e-18

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 85.14  E-value: 7.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   72 YLFPEI-----ARRRSAhllkypdAQVISLGIGDTTEPIPEVITSAMAKKAHELSTiegySGYGAEQGAKPLRAAIA--- 143
Cdd:PRK08636  16 YVFAEVnelkmAARRAG-------EDIIDFSMGNPDGPTPQHIIDKLCESAQKPKT----HGYSVSKGIYKLRLAICnwy 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  144 KTFYGGLGIGDDDVFVSDGAKCDISRLqVMFGSN---VTIaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCT- 219
Cdd:PRK08636  85 KRKYNVDLDPETEVVATMGSKEGYVHL-VQAITNpgdVAI-VPDPAYPIHSQAFILAG------------GNVHKMPLEy 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  220 ------PENGFFPDLSTVGRTDI-------IFFcsPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDD--NP 284
Cdd:PRK08636 151 nedfelDEDQFFENLEKALRESSpkpkyvvVNF--PHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGykTP 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  285 rSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSdgfpvakdFNRI-------ICTCFNGASNISQAGALAC 357
Cdd:PRK08636 229 -SILEVEGAKDVAVESYTLSKSYNMAGWRVGFVVGNKKLVGA--------LKKIkswldygMFTPIQVAATIALDGDQSC 299
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  358 LTpegleamhKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQ----SSWDVFAEILEKTHVVTTPGSGFGPG 433
Cdd:PRK08636 300 VE--------EIRETYRKRRDVLIESFANAGWELQKPRASMFVWAKIPEParhlGSLEFSKQLLTEAKVAVSPGIGFGEY 371
                        410       420
                 ....*....|....*....|....*...
gi 75163801  434 GEGFVRVSAFGHRENILEACRRFKQLYK 461
Cdd:PRK08636 372 GDEYVRIALIENENRIRQAARNIKKFLK 399
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
87-358 2.27e-17

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 83.65  E-value: 2.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   87 KYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELStiegYSGYGAEQGAKPLRAAIAKTfyggLGIGDDDVFVSDGAKCD 166
Cdd:PRK06225  24 VFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEGE----YCKYPPPEGFPELRELILKD----LGLDDDEALITAGATES 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  167 ISRLQVMFGSNVTIAVQ-DPSYpayvdsSVIMGQTGQFNTDVQkygniEYMRCTPENGF--FPDL---STVGRTDIIFFC 240
Cdd:PRK06225  96 LYLVMRAFLSPGDNAVTpDPGY------LIIDNFASRFGAEVI-----EVPIYSEECNYklTPELvkeNMDENTRLIYLI 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFeipgAEEVAMETASFSKYAGFTGVRLGWTVIP 320
Cdd:PRK06225 165 DPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEY----APEHTVTSYSFSKIFGMAGLRIGAVVAT 240
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 75163801  321 KKLLYSDGFPVAKDFnriictcfnGASNISQAGALACL 358
Cdd:PRK06225 241 PDLIEVVKSIVINDL---------GTNVIAQEAAIAGL 269
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
62-284 8.29e-17

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 81.84  E-value: 8.29e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   62 NSNMSKLQAgYLFpEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTiegysgYGAEQGAKPLRAA 141
Cdd:PRK09147   2 NPRLDRLQP-YPF-EKLRALFAGVTPPADLPPISLSIGEPKHPTPAFIKDALAANLDGLAS------YPTTAGLPALREA 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  142 IA---KTFYGGLGIgDDDVFVsdgakcdisrLQVMfGSN-----VTIAVQDPSYPAYVdssVIMGqtgqfNTDVQKY--- 210
Cdd:PRK09147  74 IAawlERRYGLPAL-DPATQV----------LPVN-GSRealfaFAQTVIDRDGPGPL---VVCP-----NPFYQIYega 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  211 -----GNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYM 279
Cdd:PRK09147 134 allagAEPYFLNCDPANNFAPDFDAVpaevwARTQLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECYSeIYF 213

                 ....*
gi 75163801  280 SDDNP 284
Cdd:PRK09147 214 DEAAP 218
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
93-364 1.58e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 80.87  E-value: 1.58e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGD----TTEPIPEVITSAMAkkahelstiEGYSGYGAEQGAKPLRAAIAKtFYG---GLGIGDDDVFVSDGAKC 165
Cdd:PRK08960  34 VIHLEIGEpdftTAEPIVAAGQAALA---------AGHTRYTAARGLPALREAIAG-FYAqryGVDVDPERILVTPGGSG 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  166 DI---SRLQVMFGSNVTIAvqDPSYPAYvdssvimgqtGQFNTDVQkyGNIEYMRCTPENGFFPDLSTVGR-----TDII 237
Cdd:PRK08960 104 ALllaSSLLVDPGKHWLLA--DPGYPCN----------RHFLRLVE--GAAQLVPVGPDSRYQLTPALVERhwnadTVGA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  238 FFCSPNNPTGAAATREQLTQLVEFAK-KNGSIIV--------Y--DSAYAMYMSDDnprsIFEIpgaeevametASFSKY 306
Cdd:PRK08960 170 LVASPANPTGTLLSRDELAALSQALRaRGGHLVVdeiyhgltYgvDAASVLEVDDD----AFVL----------NSFSKY 235
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 75163801  307 AGFTGVRLGWTVIPKKLlysdgfpvAKDFNRIICTCFNGASNISQAGALACLTPEGLE 364
Cdd:PRK08960 236 FGMTGWRLGWLVAPPAA--------VPELEKLAQNLYISASTPAQHAALACFEPETLA 285
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
87-423 9.47e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 78.61  E-value: 9.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   87 KYPDaqVISLGIGDttepiPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKtFYG---GLGIGDDDVFVSDGA 163
Cdd:PRK06348  27 KFPD--IIDLSLGD-----PDLITDESIINAAFEDAKKGHTRYTDSGGDVELIEEIIK-YYSknyDLSFKRNEIMATVGA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  164 kCD--ISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDI 236
Cdd:PRK06348  99 -CHgmYLALQSILDPGDEVIIHEPYFTPYKDQIEMVG------------GKPIILETYEEDGFQINVKKLealitSKTKA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGW 316
Cdd:PRK06348 166 IILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDFVPMATLAGMPERTITFGSFSKDFAMTGWRIGY 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  317 TVIPKKLLysdgfPVAKDFNRIICTcfnGASNISQAGALACLTPEGlEAMHKVIGFYKENTNIIIDTFTSLGY-DVYGGK 395
Cdd:PRK06348 246 VIAPDYII-----ETAKIINEGICF---SAPTISQRAAIYALKHRD-TIVPLIKEEFQKRLEYAYKRIESIPNlSLHPPK 316
                        330       340       350
                 ....*....|....*....|....*....|
gi 75163801  396 NAPYVWVHFPNQ--SSWDVFAEILEKTHVV 423
Cdd:PRK06348 317 GSIYAFINIKKTglSSVEFCEKLLKEAHVL 346
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
87-419 1.03e-15

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 78.08  E-value: 1.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    87 KYPDAQVISLGIGDTTEPIPEVITSAMAkkaHELSTIEGY-SGYGAEqgakpLRAAIAKTFygglGIGDDDVFVSDGAKC 165
Cdd:TIGR01141  16 ELGGDEVIKLNSNENPFGPPEKAKEALR---AELKKLHRYpDPDPAE-----LKQALADYY----GVDPEQILLGNGSDE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   166 DISRLQVMFG-SNVTIAVQDPSYPAYVDSSVImgqtgqFNTDVQKYGNIEYMRctpenGFFPDLSTV--GRTDIIFFCSP 242
Cdd:TIGR01141  84 IIDLLIRAFLePGDAVLVPPPTYSMYEISAKI------HGAEVVKVPLDEDGQ-----LDLEDILVAidDKPKLVFLCSP 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   243 NNPTGAAATREQLTQLVEFAKKNGsIIVYDSAYAMYMSDDNPrsifeIPGAEE---VAMeTASFSKYAGFTGVRLGWTVI 319
Cdd:TIGR01141 153 NNPTGNLFSRGDIEAVLERTPGDA-LVVVDEAYGEFSGEPST-----LPLLAEypnLIV-LRTLSKAFGLAGLRIGYAIA 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   320 PKKllysdgfpVAKDFNRIIcTCFNgASNISQAGALACLTPEgleamhkviGFYKENTNIIIDT----FTSL----GYDV 391
Cdd:TIGR01141 226 NAE--------IIDALNKVR-APFN-LSRLAQAAAIAALRDD---------DFIEATVEEINAErerlYDGLkklpGLEV 286
                         330       340
                  ....*....|....*....|....*...
gi 75163801   392 YGGKnAPYVWVHFPNQSSwDVFAEILEK 419
Cdd:TIGR01141 287 YPSD-ANFVLIRFPGDAD-ALFEALLEK 312
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
93-458 1.42e-15

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 78.18  E-value: 1.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTEPIPEVITSAMAKKAHELSTiegySGYGAEQGAKPLRAAIAKTFYGGLGIGDD---DVFVSDGAKCDISR 169
Cdd:PRK07366  32 LIDLSLGSSDLPAPAHALEAIAQSLHDPST----HGYLLFHGTLDFREAAAQWYEQRFGLAVDpetEVLPLIGSQEGTAH 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  170 --LQVMFGSNVTIaVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSP 242
Cdd:PRK07366 108 lpLAVLNPGDFAL-LLDPGYPSHAGGVYLAG------------GQIYPMPLRAENDFLPVFADIptevlAQARLMVLSYP 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA--MYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIP 320
Cdd:PRK07366 175 HNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVdlVFDGEVEPPSILQADPEKSVSIEFFTLSKSYNMGGFRIGFAIGN 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  321 KKLLYS-DGFPVAKDFNRiictcFNGASNisqaGALACLT--PEGLEAMHKVigfYKENTNIIIDTFTSLGYDVYGGKNA 397
Cdd:PRK07366 255 AQLIQAlRQVKAVVDFNQ-----YRGILN----GAIAALTgpQATVQQTVQI---FRQRRDAFINALHQIGWPVPLPEAT 322
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 75163801  398 PYVWVHFPN---QSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVsAFGHRENILE-ACRRFKQ 458
Cdd:PRK07366 323 MYVWAKLPEpwqGNSVEFCTQLVAQTGVAASPGSGFGKSGEGYVRF-ALVHDPDILEeAVERIAA 386
PRK07324 PRK07324
transaminase; Validated
129-344 6.71e-15

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 75.74  E-value: 6.71e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  129 YGAEQGAKPLRAAIAKTFYGglgIGDDDVFVSDGAkcdisrlqvmFGSN--VTIAVQDPS------YPAYvdssvimgqt 200
Cdd:PRK07324  58 YGWIEGSPEFKEAVASLYQN---VKPENILQTNGA----------TGANflVLYALVEPGdhvisvYPTY---------- 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  201 gQFNTDVQK-YG-NIEYMRCTPENGFFPDLSTVGR-----TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDS 273
Cdd:PRK07324 115 -QQLYDIPEsLGaEVDYWQLKEENGWLPDLDELRRlvrpnTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDE 193
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75163801  274 AYAMYMSDDNPRSIFEIpgaEEVAMETASFSKYAGFTGVRLGWTVIPKKLLysDGFPVAKDFNRIICTCFN 344
Cdd:PRK07324 194 VYRPLDEDGSTPSIADL---YEKGISTNSMSKTYSLPGIRVGWIAANEEVI--DILRKYRDYTMICAGVFD 259
PRK08363 PRK08363
alanine aminotransferase; Validated
92-316 7.19e-15

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 76.00  E-value: 7.19e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   92 QVISLGIGDTT----EPiPEVITSAMAKkahelSTIEGYSGYGAEQGAKPLRAAIAK--TFYGGLGIGDDDVFVSDGAKc 165
Cdd:PRK08363  31 KVIRLNIGDPVkfdfQP-PEHMKEAYCR-----AIKEGHNYYGPSEGLPELREAIVKreKRKNGVDITPDDVRVTAAVT- 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  166 diSRLQVMFGSNVT----IAVQDPSYPAYVDSsvimgqtgqfntdVQKYGNI--EYmRCTPENGFFPDLSTV-----GRT 234
Cdd:PRK08363 104 --EALQLIFGALLDpgdeILIPGPSYPPYTGL-------------VKFYGGVpvEY-RTIEEEGWQPDIDDIrkkitEKT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  235 DIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETAsFSKYAGFTGVRL 314
Cdd:PRK08363 168 KAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEGKHVSPGSLTKDVPVIVMNG-LSKVYFATGWRL 246

                 ..
gi 75163801  315 GW 316
Cdd:PRK08363 247 GY 248
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
89-406 1.04e-14

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 75.45  E-value: 1.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    89 PDAQVISLGIGDTTePIPEVITSAMAKKA--HELSTIEgYSGYGAEQGAKPLRAAIAKTFYGGLG--IGDDDVFVSDGAK 164
Cdd:TIGR01265  29 PEKPVIPLSHGDPS-VFGNLRTDPEAEEAvkDALRSGK-FNGYAPSVGALAAREAVAEYLSSDLPgkLTADDVVLTSGCS 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   165 CDISR-LQVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfnTDVQKYgnieymRCTPENGFFPDLSTVG-----RTDIIF 238
Cdd:TIGR01265 107 QAIEIcIEALANPGANILVPRPGFPLYDTRAAFSG------LEVRLY------DLLPEKDWEIDLDGLEsladeKTVAIV 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   239 FCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPrsiFEIPG--AEEVAMET-ASFSKYAGFTGVRLG 315
Cdd:TIGR01265 175 VINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAP---FIPMAsfASIVPVLSlGGISKRWVVPGWRLG 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   316 WTVI--PKKLLYSDGFPVAKDFNRIICtcfnGASNISQaGALACL---TPEglEAMHKVIGFYKENTNIIIDTFTSL-GY 389
Cdd:TIGR01265 252 WIIIhdPHGIFRDTVLQGLKNLLQRIL----GPATIVQ-GALPDIlenTPQ--EFFDGKISVLKSNAELCYEELKDIpGL 324
                         330       340
                  ....*....|....*....|..
gi 75163801   390 DVYGGKNAPYVWV-----HFPN 406
Cdd:TIGR01265 325 VCPKPEGAMYLMVkleleLFPE 346
PRK05166 PRK05166
histidinol-phosphate transaminase;
135-391 1.26e-14

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 75.17  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  135 AKPLRAAIAKTFygglGIGDDDVFVSDGAKcDISRL--QVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGN 212
Cdd:PRK05166  73 GRALREAIAART----GVPADRIILGNGSE-DLIAVicRAVLRPGDRVVTLYPSFPLHEDYPTMMG------------AR 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  213 IEYMRCTPENGFFPD--LSTVGRT-DIIFFCSPNNPTGAAATREQLTQLVEfAKKNGSIIVYDSAYAMYMSDDNPRSIFE 289
Cdd:PRK05166 136 VERVTVTPDLGFDLDalCAAVARApRMLMFSNPSNPVGSWLTADQLARVLD-ATPPETLIVVDEAYAEYAAGDDYPSALT 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  290 I---PGAEEVAMETasFSKYAGFTGVRLGWTVIpkkllySDGFPVAKdFNRIIcTCFNgASNISQAGALACLTPEglEAM 366
Cdd:PRK05166 215 LlkaRGLPWIVLRT--FSKAYGLAGLRVGYGLV------SDPELVGL-LDRVR-TPFN-VNGAAQAAALAALDDE--EHL 281
                        250       260
                 ....*....|....*....|....*
gi 75163801  367 HKVIGFYKENTNIIIDTFTSLGYDV 391
Cdd:PRK05166 282 AKGVALALAERERLKKELAEMGYRI 306
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
92-382 4.29e-14

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 73.73  E-value: 4.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   92 QVISLGIGDTTEPIPEVITSAMAKkaHELSTIEgysgYGAEQGAKPLRAAIAKtFYGGLGI--GDDDVFVSDGAKCDIS- 168
Cdd:PRK07568  31 KVYHLNIGQPDIKTPEVFFEAIKN--YDEEVLA----YSHSQGIPELREAFAK-YYKKWGIdvEPDEILITNGGSEAILf 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMFGSNVTIAVQDPSYPAYvdssviMGQTGQFNTdvqkygNIEYMRCTPENGF-FPDLSTV-----GRTDIIFFCSP 242
Cdd:PRK07568 104 AMMAICDPGDEILVPEPFYANY------NGFATSAGV------KIVPVTTKIEEGFhLPSKEEIeklitPKTKAILISNP 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  243 NNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNP-RSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 321
Cdd:PRK07568 172 GNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKyTSALSLEGLEDRVIIIDSVSKRYSACGARIGCLISKN 251
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75163801  322 KLLYSDGFPVAKdfNRIictcfnGASNISQAGALACL-TPEglEAMHKVIGFYKENTNIIID 382
Cdd:PRK07568 252 KELIAAAMKLCQ--ARL------SPPTLEQIGAAALLdTPE--SYFDEVREEYKKRRDILYE 303
PRK07550 PRK07550
aminotransferase;
103-459 9.27e-14

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 72.68  E-value: 9.27e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  103 EPIPEVITSAMAKKAHELSTiegySGYGAEQGAKPLRAAIA---KTFYGGlGIGDDDVFVSDGAK----CDISRLQvmfG 175
Cdd:PRK07550  41 YPPPPELLRALAEAAADPAA----HLYGPVEGLPELREAYAahySRLYGA-AISPEQVHITSGCNqafwAAMVTLA---G 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  176 SNVTIAVQDPSYpayvdssvimgqtgqFNTD--VQKYG-NIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTG 247
Cdd:PRK07550 113 AGDEVILPLPWY---------------FNHKmwLDMLGiRPVYLPCDEGPGLLPDPAAAEalitpRTRAIALVTPNNPTG 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  248 AAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDN-PRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLys 326
Cdd:PRK07550 178 VVYPPELLHELYDLARRHGIALILDETYRDFDSGGGaPHDLFADPDWDDTLVHLYSFSKSYALTGHRVGAVVASPARI-- 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  327 dgFPVAK--DfNRIICtcfngASNISQAGALAcltpeGLEAMHkviGFYKEN-------TNIIIDTFTSL-GYDVyGGKN 396
Cdd:PRK07550 256 --AEIEKfmD-TVAIC-----APRIGQIAVAW-----GLPNLA---DWRAGNraeiarrRDAFRAVFARLpGWEL-LASG 318
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75163801  397 APYVWVH--FPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVsAFGH--RENILEACRRFKQL 459
Cdd:PRK07550 319 AYFAYVRhpFPDRPSREVARRLAKEAGILCLPGTMFGPGQEGYLRL-AFANadVAGIGELVERLRAF 384
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
93-358 1.21e-13

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 72.28  E-value: 1.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTEPIPEVITSAMAKkahelSTIEGYSGYGAEQGAKPLRAAIAKtFYG---GLGIGDDDVFVSDGAkcdISR 169
Cdd:PRK06108  26 VLPLWFGESDLPTPDFIRDAAAA-----ALADGETFYTHNLGIPELREALAR-YVSrlhGVATPPERIAVTSSG---VQA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  170 LQVMF------GSNVtIAVQdPSYPAYVDSSVIMG----------QTGQFNTDVQKygnIEyMRCTPengffpdlstvgR 233
Cdd:PRK06108  97 LMLAAqalvgpGDEV-VAVT-PLWPNLVAAPKILGarvvcvpldfGGGGWTLDLDR---LL-AAITP------------R 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR--SIFEIPGAEEVAMETASFSKYAGFTG 311
Cdd:PRK06108 159 TRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRapSFLDIAEPDDRIIFVNSFSKNWAMTG 238
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 75163801  312 VRLGWTVIPKKLlysdgfpvAKDFNRIICTCFNGASNISQAGALACL 358
Cdd:PRK06108 239 WRLGWLVAPPAL--------GQVLEKLIEYNTSCVAQFVQRAAVAAL 277
PRK03321 PRK03321
putative aminotransferase; Provisional
233-423 4.19e-12

putative aminotransferase; Provisional


Pssm-ID: 179559  Cd Length: 352  Bit Score: 67.30  E-value: 4.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  233 RTDIIFFCSPNNPTGAAATREQLTQLVEfAKKNGSIIVYDSAYAMYMSDDnprsifEIPGAEE--------VAMETasFS 304
Cdd:PRK03321 145 RTRLIFVCNPNNPTGTVVTPAELARFLD-AVPADVLVVLDEAYVEYVRDD------DVPDGLElvrdhpnvVVLRT--FS 215
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  305 KYAGFTGVRLGWTVipkkllysdGFPVAKDFNRIICTCFnGASNISQAGALACLTPEGlEAMHKVIGFYKENTNiIIDTF 384
Cdd:PRK03321 216 KAYGLAGLRVGYAV---------GHPEVIAALRKVAVPF-SVNSLAQAAAIASLAAED-ELLERVDAVVAERDR-VRAAL 283
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 75163801  385 TSLGYDVYGGKnAPYVWvhFPNQSSWDVFAEILEKTHVV 423
Cdd:PRK03321 284 RAAGWTVPPSQ-ANFVW--LPLGERTADFAAAAAEAGVV 319
PRK09265 PRK09265
aminotransferase AlaT; Validated
106-322 4.64e-12

aminotransferase AlaT; Validated


Pssm-ID: 181738  Cd Length: 404  Bit Score: 67.53  E-value: 4.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  106 PEVITSAMAkkaHELSTIEGYSgygAEQGAKPLRAAIAkTFYGGLGIGD---DDVFVSDGAkcdiSRLQVMF-------G 175
Cdd:PRK09265  51 PDEILRDVI---RNLPTAQGYS---DSKGLFSARKAIM-QYYQQKGIPDvdvDDIYIGNGV----SELIVMAmqallnnG 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  176 SNVTIAVqdPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAA 250
Cdd:PRK09265 120 DEVLVPA--PDYPLWTAAVSLSG------------GKPVHYLCDEEAGWFPDLDDIrskitPRTKAIVIINPNNPTGAVY 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  251 TREQLTQLVEFAKKNGSIIVYDSAYAMYMSDdnprsifeipGAEEVAMETAS----------FSK-Y--AGFtgvRLGWT 317
Cdd:PRK09265 186 SKELLEEIVEIARQHNLIIFADEIYDKILYD----------GAVHISIASLApdllcvtfngLSKaYrvAGF---RVGWM 252

                 ....*..
gi 75163801  318 VI--PKK 322
Cdd:PRK09265 253 VLsgPKK 259
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
94-388 8.43e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 66.63  E-value: 8.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIGDTTEPIPEVITSAMAK-----KAHElstiegysgYGAEQGAKPLRAAIAKTF--YGGLGIGDDD-VFVSDGAKc 165
Cdd:PRK05957  30 ISLGQGVVSYPPPPEAIEALNNflanpENHK---------YQAVQGIPPLLEAITQKLqqDNGIELNNEQaIVVTAGSN- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  166 disrlqvMFGSNVTIAVQDPSypayvdSSVIMGQTGQFNTDVQkygnIEYMRCTP-----ENGFFPDLSTV-----GRTD 235
Cdd:PRK05957 100 -------MAFMNAILAITDPG------DEIILNTPYYFNHEMA----ITMAGCQPilvptDDNYQLQPEAIeqaitPKTR 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSKYAGFTGVRL 314
Cdd:PRK05957 163 AIVTISPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHfSPGSIPGSGNHTISLYSLSKAYGFASWRI 242
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 75163801  315 GWTVIPKKLLYsdgfPVAKDFNRI-ICtcfngASNISQAGALACLTpEGLEAMHKVIGFYKENTNIIIDTFTSLG 388
Cdd:PRK05957 243 GYMVIPIHLLE----AIKKIQDTIlIC-----PPVVSQYAALGALQ-VGKSYCQQHLPEIAQVRQILLKSLGQLQ 307
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
89-458 1.18e-11

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 66.34  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801    89 PDAQVISLGIGDTTE----PIPEVITSAMakkaHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLG-IGDDDVFVSDGA 163
Cdd:TIGR01264  29 PEKPMIKLSIGDPTVfgnlPTDPEVMQAM----KDSLDSGKYNGYAPTVGALSAREAIASYYHNPDGpIEADDVVLCSGC 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   164 KCDISR-LQVMFGSNVTIAVQDPSYPAYvdssvimgqtgqfNTDVQKYG-NIEYMRCTPENGFFPDLSTVG-----RTDI 236
Cdd:TIGR01264 105 SHAIEMcIAALANAGQNILVPRPGFPLY-------------ETLAESMGiEVKLYNLLPDKSWEIDLKQLEslideKTAA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   237 IFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMymsddnprsiFEIPGAEEVAMETAS----------FSKY 306
Cdd:TIGR01264 172 LIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGD----------MVFSGATFEPLASLSstvpilscggLAKR 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   307 AGFTGVRLGWtvipkkLLYSDGFPVAKDFN---RIICTCFNGASNISQaGALA---CLTPEglEAMHKVIGFYKENTNII 380
Cdd:TIGR01264 242 WLVPGWRLGW------IIIHDRRGILRDIRdglVKLSQRILGPCTIVQ-GALPsilLRTPQ--EYFDGTLSVLESNAMLC 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   381 IDTFTSL-GYDVYGGKNAPYVWV-----HFPNQSSwDV-FAEIL---EKTHVVTtpgsGFGPGGEGFVRVSAFGHRENIL 450
Cdd:TIGR01264 313 YGALAAVpGLRPVMPSGAMYMMVgiemeHFPEFKN-DVeFTERLvaeQSVFCLP----GSCFEYPGFFRVVLTVPVVMME 387

                  ....*...
gi 75163801   451 EACRRFKQ 458
Cdd:TIGR01264 388 EACSRIQE 395
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
128-419 1.78e-11

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 66.01  E-value: 1.78e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 128 GYGAEQGAKPLRAAIAKTFYG-GLGIGDDDVFVSDGAKC--DISrLQVMFGSNVTIAVQDPSYPAYVDssvIMGQTGqfn 204
Cdd:COG1167 143 GYGDPQGLPELREAIARYLARrGVPASPDQILITSGAQQalDLA-LRALLRPGDTVAVESPTYPGALA---ALRAAG--- 215
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 205 tdvqkygnieyMRCTP----ENGFFPDL--STVGRTDI-IFFCSPN--NPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275
Cdd:COG1167 216 -----------LRLVPvpvdEDGLDLDAleAALRRHRPrAVYVTPShqNPTGATMSLERRRALLELARRHGVPIIEDDYD 284
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 276 A-MYMSDDNPRSIFEIPGAEEVaMETASFSKYAgFTGVRLGWTVIPKKLlysdgfpvAKDFNRIICTCFNGASNISQAGA 354
Cdd:COG1167 285 SeLRYDGRPPPPLAALDAPGRV-IYIGSFSKTL-APGLRLGYLVAPGRL--------IERLARLKRATDLGTSPLTQLAL 354
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75163801 355 LACLTpEG-----LEAMHKVigfYKENTNIIIDTFTSL---GYDVYGGKNAPYVWVHFPNQSSWDVFAEILEK 419
Cdd:COG1167 355 AEFLE-SGhydrhLRRLRRE---YRARRDLLLAALARHlpdGLRVTGPPGGLHLWLELPEGVDAEALAAAALA 423
PLN02656 PLN02656
tyrosine transaminase
92-319 1.18e-10

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 63.02  E-value: 1.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   92 QVISLGIGD--------TTEPIPEVITSAMAKkahelstiEGYSGYGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVSD 161
Cdd:PLN02656  32 RVISLGMGDptayscfhTTHVAQEAVVDALQS--------NKFNGYAPTVGLPQARRAIAEYLSRDLpyKLSLDDVFITS 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  162 GAKCDIS-RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQtgqfntdvqkygNIEYMRCTPENGFFPDLSTV-----GRTD 235
Cdd:PLN02656 104 GCTQAIDvALSMLARPGANILLPRPGFPIYELCAAFRHL------------EVRYVDLLPEKGWEVDLDAVealadQNTV 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  236 IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLG 315
Cdd:PLN02656 172 ALVIINPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVFGSIVPVLTLGSLSKRWIVPGWRLG 251

                 ....
gi 75163801  316 WTVI 319
Cdd:PLN02656 252 WFVT 255
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
94-335 1.54e-10

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 62.75  E-value: 1.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIG--DTTEPipevitSAMAKKAHElSTIEGYSGYGAEQGAKPLRAAIA---KTFYGGLGIGDDDVFVSDGAKCDIS 168
Cdd:PRK07777  27 VNLGQGfpDEDGP------PEMLEAAQE-AIAGGVNQYPPGPGIPELRAAIAaqrRRRYGLEYDPDTEVLVTVGATEAIA 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMF---GSNVtIAVQdPSYPAYVDSSVIMGQTGQFNTDVQkygnieymrctPENGFFPDL----STVG-RTDIIFFC 240
Cdd:PRK07777 100 AAVLGLvepGDEV-LLIE-PYYDSYAAVIAMAGAHRVPVPLVP-----------DGRGFALDLdalrAAVTpRTRALIVN 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNP-RSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319
Cdd:PRK07777 167 SPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARhLPLATLPGMRERTVTISSAAKTFNVTGWKIGWACG 246
                        250
                 ....*....|....*.
gi 75163801  320 PKKLLysDGFPVAKDF 335
Cdd:PRK07777 247 PAPLI--AAVRAAKQY 260
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
106-335 2.20e-10

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 62.45  E-value: 2.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  106 PEVITSAMAkkaHELSTIEGYSgygAEQGAKPLRAAIAKtFYGGLGIGD---DDVFVSDGakcdISRLQVMFGSNV---- 178
Cdd:PRK13355 164 PDEVVYDMA---QQLTDTEGYS---DSKGLFSARKAIMQ-YAQLKGLPNvdvDDIYTGNG----VSELINLSMSALlddg 232
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  179 -TIAVQDPSYPAYVDSSVIMGQTGqfntdvqkygnIEYmRCTPENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATR 252
Cdd:PRK13355 233 dEVLIPSPDYPLWTACVNLAGGTA-----------VHY-RCDEQSEWYPDIDDIrskitSRTKAIVIINPNNPTGALYPR 300
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  253 EQLTQLVEFAKKNGSIIVYDSAYAMYMSDdnprsifeipGAEEVAMET----------ASFSKYAGFTGVRLGWTVIpkk 322
Cdd:PRK13355 301 EVLQQIVDIAREHQLIIFSDEIYDRLVMD----------GLEHTSIASlapdlfcvtfSGLSKSHMIAGYRIGWMIL--- 367
                        250
                 ....*....|...
gi 75163801  323 llySDGFPVAKDF 335
Cdd:PRK13355 368 ---SGNKRIAKDY 377
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
73-402 8.60e-10

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 60.21  E-value: 8.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   73 LFPEIARRRSahllKYPDAQVISLGIGDTTEPIPEVITSAMAKKA-HELSTIEGY---SGYGAeqgakpLRAAIA----K 144
Cdd:PRK06836  19 MFEEGARLKA----EYGADNVFDFSLGNPSVPPPAAVKEALRELAeEEDPGLHGYmpnAGYPE------VREAIAeslnR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  145 TFygGLGIGDDDVFVSDGAKCDIsrlqvmfgsNVTI-AVQDPS------------YPAYVDSsvimgqTGQFNTDVQkyg 211
Cdd:PRK06836  89 RF--GTPLTADHIVMTCGAAGAL---------NVALkAILNPGdevivfapyfveYRFYVDN------HGGKLVVVP--- 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  212 nieymrcTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEF----AKKNGSII--VYDSAYA--MY 278
Cdd:PRK06836 149 -------TDTDTFQPDLDALEaaitpKTKAVIINSPNNPTGVVYSEETLKALAALleekSKEYGRPIylISDEPYReiVY 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  279 MSDDNPrsifEIPGAEEVAMETASFSKYAGFTGVRLGWTVIP-----KKLLYsDGFPVAkdfNRIicTCFNGASNISQAG 353
Cdd:PRK06836 222 DGAEVP----YIFKYYDNSIVVYSFSKSLSLPGERIGYIAVNpemedADDLV-AALVFA---NRI--LGFVNAPALMQRV 291
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 75163801  354 ALACLTpegleamHKV-IGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWV 402
Cdd:PRK06836 292 VAKCLD-------ATVdVSIYKRNRDLLYDGLTELGFECVKPQGAFYLFP 334
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
94-339 1.30e-09

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 60.03  E-value: 1.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIGDT-------TEPIPEVITSAMAKKAHelstiegYSGYGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVSDGAK 164
Cdd:PLN00143  35 ISFGFGDPscfecfrTTNIAEDAIVEAVRSAK-------FNSYAPTGGILPARRAIADYLSNDLpyQLSPDDVYLTLGCK 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  165 CDIS-RLQVMFGSNVTIAVQDPSYPayvdssvimgqtgqfntDVQKYGN-----IEYMRCTPENGFFPDLSTVG-----R 233
Cdd:PLN00143 108 HAAEiIIKVLARPEANILLPRPGFP-----------------DVETYAIfhhleIRHFDLLPEKGWEVDLDAVEaiadeN 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  234 TDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVR 313
Cdd:PLN00143 171 TIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGLFASIVPVITLGSISKRWMIPGWG 250
                        250       260
                 ....*....|....*....|....*...
gi 75163801  314 LGWTVI--PKKLLYSDGfpVAKDFNRII 339
Cdd:PLN00143 251 LGWLVTcdPSGLLQICE--IADSIKKAL 276
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
93-324 1.68e-09

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 59.40  E-value: 1.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTePIPEVITSAMAKKAHELSTIEG-YSGYGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVSDGAKCDISR 169
Cdd:PLN00145  54 VLPLGHGDPS-AFPCFRTAPEAEDAVAAALRSGkYNSYSTCVGLLPARRAIAEYLSRDLpyELSTDDIYLTAGCAQAIEI 132
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  170 LQVMF---GSNvtIAVQDPSYPAYVDSSVimgqtgqfntdvqkYGNIE--YMRCTPENGFFPDLSTV-----GRTDIIFF 239
Cdd:PLN00145 133 IMSVLaqpGAN--ILLPRPGYPLYEARAV--------------FSGLEvrHFDLLPERGWEVDLEGVealadENTVAMVI 196
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319
Cdd:PLN00145 197 INPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVFGEVAPVLTLGSISKRWVVPGWRLGWIAT 276

                 ....*..
gi 75163801  320 --PKKLL 324
Cdd:PLN00145 277 cdPNGIL 283
PLN00175 PLN00175
aminotransferase family protein; Provisional
233-405 4.36e-09

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 58.34  E-value: 4.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGV 312
Cdd:PLN00175 187 KTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGDHISMASLPGMYERTVTMNSLGKTFSLTGW 266
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  313 RLGWTVIPKKLLYsdGFPVAKDFnriicTCFNGASNISQAGALACLTPEGLEAmhKVIGFYKENTNIIIDTFTSLGYDVY 392
Cdd:PLN00175 267 KIGWAIAPPHLTW--GVRQAHSF-----LTFATATPMQWAAVAALRAPESYYE--ELKRDYSAKKDILVEGLKEVGFKVY 337
                        170
                 ....*....|....
gi 75163801  393 GGKNAPYVWV-HFP 405
Cdd:PLN00175 338 PSSGTYFVMVdHTP 351
PRK06107 PRK06107
aspartate transaminase;
75-359 8.23e-09

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 57.44  E-value: 8.23e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   75 PEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAmakkAHElsTIE-GYSGYGAEQGAKPLRAAIAKTFYGGLGI- 152
Cdd:PRK06107  17 PSTAAAARARELRAAGRSIVDLTVGEPDFDTPDHIKQA----AVA--AIErGETKYTLVNGTPALRKAIIAKLERRNGLh 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  153 -GDDDVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDssVIMGQTGqfnTDVqkygnieYMRCTPENGFF--PDL 228
Cdd:PRK06107  91 yADNEITVGGGAKQAIfLALMATLEAGDEVIIPAPYWVSYPD--MVLANDG---TPV-------IVACPEEQGFKltPEA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  229 ---STVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVY-DSAYAMYMSDDNPRS--IFEIPGAEEVAMETAS 302
Cdd:PRK06107 159 leaAITPRTRWLILNAPSNPTGAVYSRAELRALADVLLRHPHVLVLtDDIYDHIRFDDEPTPhlLAAAPELRDRVLVTNG 238
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 75163801  303 FSKYAGFTGVRLGWTVIPKKLLYSdgfpvakdFNRIICTCFNGASNISQAGALACLT 359
Cdd:PRK06107 239 VSKTYAMTGWRIGYAAGPADLIAA--------INKLQSQSSSCPSSISQAAAAAALN 287
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
95-289 1.04e-08

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 57.00  E-value: 1.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   95 SLGIGDTTEPIPEVITSAMAKKAHELSTiegysgYGAEQGAKPLRAA----IAKTFygGLGIGDDDVFVSDGAKcdisrl 170
Cdd:PRK05839  28 DLTIGEPQFETPKFIQDALKNNAHLLNK------YPKSAGEESLREAqrgfFKRRF--KIELKENELIPTFGTR------ 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  171 QVMFG---------SNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRCTPENGFFPDLS--TVGRTDIIFF 239
Cdd:PRK05839  94 EVLFNfpqfvlfdkQNPTIAYPNPFYQIYEGAAIASR------------AKVLLMPLTKENDFTPSLNekELQEVDLVIL 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 75163801  240 CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFE 289
Cdd:PRK05839 162 NSPNNPTGRTLSLEELIEWVKLALKHDFILINDECYSEIYENTPPPSLLE 211
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
93-457 1.23e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 56.66  E-value: 1.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   93 VISLGIGDTTEPIPEVITSAmAKKAHElstiEGYSGYGAEQGAKPLRAAIA---KTFYGGLGIGDDDVFVSDGAKCDIS- 168
Cdd:PRK07309  32 ILKLTLGEPDFTTPDHVKEA-AKRAID----ANQSHYTGMAGLLELRQAAAdfvKEKYNLDYAPENEILVTIGATEALSa 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  169 RLQVMFGSNVTIAVQDPSYPAYVDSSVIMGqtgqfntdvqkyGNIEYMRcTPENGFF--PD------LSTVGRTDIIFFC 240
Cdd:PRK07309 107 SLTAILEPGDKVLLPAPAYPGYEPIVNLVG------------AEIVEID-TTENDFVltPEmlekaiLEQGDKLKAVILN 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  241 SPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSIFEIpgAEEVAMETASFSKYAGFTGVRLGWTVI 319
Cdd:PRK07309 174 YPANPTGVTYSREQIKALADVLKKYDIFVISDEVYSeLTYTGEPHVSIAEY--LPDQTILINGLSKSHAMTGWRIGLIFA 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  320 PKKLLYSdgfpvAKDFNRIICTcfnGASNISQAGALACLTpEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPY 399
Cdd:PRK07309 252 PAEFTAQ-----LIKSHQYLVT---AATTMAQFAAVEALT-NGKDDALPMKKEYIKRRDYIIEKMTDLGFKIIKPDGAFY 322
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75163801  400 VWVHFP---NQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFK 457
Cdd:PRK07309 323 IFAKIPagyNQDSFKFLQDFARKKAVAFIPGAAFGPYGEGYVRLSYAASMETIKEAMKRLK 383
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
233-316 2.56e-08

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 55.64  E-value: 2.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAkknGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMeTASFSKYAGFTGV 312
Cdd:PRK03317 160 RPDVVFLTSPNNPTGTALPLDDVEAILDAA---PGIVVVDEAYAEFRRSGTPSALTLLPEYPRLVV-SRTMSKAFAFAGG 235

                 ....
gi 75163801  313 RLGW 316
Cdd:PRK03317 236 RLGY 239
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
236-324 7.37e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 54.28  E-value: 7.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  236 IIFFCSPNNPTGAAATREQLTQLVEfAKKNGSIIVYDSAYAMYmsDDNPRSIFEIPGAEEV-AMETasFSKYAGFTGVRL 314
Cdd:PRK09105 168 LIYICNPNNPTGTVTPRADIEWLLA-NKPAGSVLLVDEAYIHF--SDAPSVVDLVAQRKDLiVLRT--FSKLYGMAGMRL 242
                         90
                 ....*....|
gi 75163801  315 GWTVIPKKLL 324
Cdd:PRK09105 243 GLAAARPDLL 252
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
72-272 4.73e-07

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 51.63  E-value: 4.73e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  72 YLFPEIARRRSAHLLK-------YPDAQVISLGIGDTTEPIPEVITSAMAKKA-HElstIEGYSGYGAEqgakpLRAAIA 143
Cdd:COG1168   3 YDFDTIIDRRGTGSVKwdgledrFGGEDVLPMWVADMDFATPPAVIEALKERVeHG---VFGYTAPPDE-----YYEAII 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801 144 ---KTFYGgLGIGDDDVFVSDGakcdisrlqVMFGSNVTI----------AVQDPSYPAyvdssvimgqtgqFNTDVQKY 210
Cdd:COG1168  75 dwlKRRHG-WEIDPEWIVFTPG---------VVPGLALAIraftepgdgvLIQTPVYPP-------------FFKAIENN 131
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801 211 G-NIEYMRCTPENGF----FPDLSTV--GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYD 272
Cdd:COG1168 132 GrELVENPLILEDGRyridFDDLEAKldPGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISD 200
L_thr_O3P_dcar TIGR01140
L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding ...
132-315 5.37e-07

L-threonine-O-3-phosphate decarboxylase; This family contains pyridoxal phosphate-binding class II aminotransferases (see pfamAM:pfam00222) closely related to, yet distinct from, histidinol-phosphate aminotransferase (HisC). It is found in cobalamin biosynthesis operons in Salmonella typhimurium and Bacillus halodurans (each of which also has HisC) and has been shown to have L-threonine-O-3-phosphate decarboxylase activity in Salmonella. Although the gene symbol cobD was assigned in Salmonella, cobD in other contexts refers to a different cobalamin biosynthesis enzyme, modeled by pfam03186 and called cbiB in Salmonella. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 273466  Cd Length: 330  Bit Score: 51.42  E-value: 5.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   132 EQGAKPLRAAIAKTFygglGIGDDDVFVSDGAKCDISRL-QVMFGSNVTIAVqdPSYPAYVDSSVIMGQTgqfntdVQKY 210
Cdd:TIGR01140  46 DPEYDELRAAAAAYY----GLPAASVLPVNGAQEAIYLLpRLLAPGRVLVLA--PTYSEYARAWRAAGHE------VVEL 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   211 GNIEYMRCTPEngffpdlstvgRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDdnprsifei 290
Cdd:TIGR01140 114 PDLDRLPAALE-----------EADLLVVCNPNNPTGRLIPPETLLALAARLRARGGWLVVDEAFIDFTPD--------- 173
                         170       180       190
                  ....*....|....*....|....*....|....
gi 75163801   291 pgaEEVAMETA---------SFSKYAGFTGVRLG 315
Cdd:TIGR01140 174 ---ASLAPQAArfpglvvlrSLTKFFGLAGLRLG 204
avtA PRK09440
valine--pyruvate transaminase; Provisional
86-413 1.35e-06

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 50.24  E-value: 1.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   86 LKYPDAqvISLGIGDTTEpIPEVIT---SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTF--YGGLGIGDDDVFVS 160
Cdd:PRK09440  27 LRTPGA--IMLGGGNPAH-IPEMEDyfrDLLADLLASGKLTEALGNYDGPQGKDELIEALAALLneRYGWNISPQNIALT 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  161 DGAK--------------CDISRLQVMFgsnvTIAvqdPSYPAYVDSSVimgQTGQFntdVQKYGNIEYMrctpENGFF- 225
Cdd:PRK09440 104 NGSQsaffylfnlfagrrADGSLKKILF----PLA---PEYIGYADAGL---EEDLF---VSYRPNIELL----PEGQFk 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  226 --PDLSTVGRTD---IIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMsddnPRSIFeipgaEEVAM-- 298
Cdd:PRK09440 167 yhVDFEHLHIDEdtgAICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDNAYGPPF----PGIIF-----SEATPlw 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  299 -----ETASFSKyAGFTGVRLGWTVIPKKLLysdgfPVAKDFNRIICTCfngASNISQA--------GALACLTpeglea 365
Cdd:PRK09440 238 npniiLCMSLSK-LGLPGVRCGIVIADEEII-----EALSNMNGIISLA---PGRLGPAiaaemiesGDLLRLS------ 302
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 75163801  366 mHKVIG-FYKENTNIIIDT----FTSLGYDVYGGKNAPYVWVHFPNQ--SSWDVF 413
Cdd:PRK09440 303 -ETVIRpFYRQKVQLAIALlrryLPDEPCLIHKPEGAIFLWLWFKDLpiTTEELY 356
PRK06855 PRK06855
pyridoxal phosphate-dependent aminotransferase;
217-317 2.49e-06

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180734  Cd Length: 433  Bit Score: 49.56  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  217 RCTPENGFFPDL-----------STVGrtdiIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNP 284
Cdd:PRK06855 148 RLDPENNWYPDLddlenkvkynpSIAG----ILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNnIVYNGKKT 223
                         90       100       110
                 ....*....|....*....|....*....|....
gi 75163801  285 RSIFEIPGaeEV-AMETASFSKYAGFTGVRLGWT 317
Cdd:PRK06855 224 VPLSEVIG--DVpGIALKGISKELPWPGSRCGWI 255
PRK08354 PRK08354
putative aminotransferase; Provisional
231-316 4.03e-06

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 48.57  E-value: 4.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  231 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYamymsddnprsIFEIPGAEEVAMETA----SFSKY 306
Cdd:PRK08354 115 VERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAF-----------IDFVKKPESPEGENIiklrTFTKS 183
                         90
                 ....*....|
gi 75163801  307 AGFTGVRLGW 316
Cdd:PRK08354 184 YGLPGIRVGY 193
PTZ00376 PTZ00376
aspartate aminotransferase; Provisional
170-315 1.03e-05

aspartate aminotransferase; Provisional


Pssm-ID: 240390  Cd Length: 404  Bit Score: 47.61  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  170 LQVMFGSNVTIAVQDPSYPAYVDssvIMGQTGQfntdvqKYGNIEY----MRCTPENGFFPDLSTVGRTDIIFF--CSpN 243
Cdd:PTZ00376 117 LKRFLPAGTTVYVSNPTWPNHVN---IFKSAGL------NVKEYRYydpkTKGLDFDGMLEDLRTAPNGSVVLLhaCA-H 186
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 75163801  244 NPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAME---TASFSKYAGFTGVRLG 315
Cdd:PTZ00376 187 NPTGVDPTEEQWKEIADVMKRKNLIPFFDMAYQGFASGDLDKDAYAIRLFAERGVEflvAQSFSKNMGLYGERIG 261
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
94-357 2.89e-05

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 46.32  E-value: 2.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   94 ISLGIGDTTEP----IPEVITSAMAKkahelsTIEG--YSGYGAEQGAKPLRAAIAkTFYGG------------------ 149
Cdd:PTZ00433  36 IKLSVGDPTLDgnllTPAIQTKALVE------AVDSqeCNGYPPTVGSPEAREAVA-TYWRNsfvhkeslkstikkdnvv 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  150 LGIGDDDVF-VSDGAKCDIsrlqvmfGSNvtIAVQDPSYPAYvDSsvimgqtgqfntdVQKYGNIE--YMRCTPENGFFP 226
Cdd:PTZ00433 109 LCSGVSHAIlMALTALCDE-------GDN--ILVPAPGFPHY-ET-------------VCKAYGIEmrFYNCRPEKDWEA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  227 DLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA-MYMSDDNPRSI--FEIPGAEEVAM 298
Cdd:PTZ00433 166 DLDEIrrlvdDRTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAgMVFNGATFTSVadFDTTVPRVILG 245
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 75163801  299 ETAsfsKYAGFTGVRLGWtvipkkLLYSDGFPVAKDFNRiictcfnGASNISQAGALAC 357
Cdd:PTZ00433 246 GTA---KNLVVPGWRLGW------LLLVDPHGNGGDFLD-------GMKRLGMLVCGPC 288
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
112-311 2.95e-05

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 46.11  E-value: 2.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  112 AMAKKAHELSTIEGYSG-YGAEQGAKPLRAAIAK--TFYGGLGIGDDDVFVSDGAKCDISR-LQVMFG-SNVTIAVQDPS 186
Cdd:PTZ00377  93 VVARAKEYLNAIGGGTGaYTDSAGYPFVRKAVAAfiERRDGVPKDPSDIFLTDGASSGIKLlLQLLIGdPSDGVMIPIPQ 172
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  187 YPAYvdSSVIMgqtgQFNTDVQKYGNIEymrctpENGFFPDLSTV----------GRTDIIFFC-SPNNPTGAAATREQL 255
Cdd:PTZ00377 173 YPLY--SAAIT----LLGGKQVPYYLDE------EKGWSLDQEELeeayeqavrnGITPRALVViNPGNPTGQVLTRDVM 240
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 75163801  256 TQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSI------FEIPGAEEVAMETASF---SKyaGFTG 311
Cdd:PTZ00377 241 EEIIKFCYEKGIVLMADEVYQENIYDGEKPFIsfrkvlLELPAEYNTDVELVSFhstSK--GIIG 303
PRK09275 PRK09275
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
237-315 1.17e-04

bifunctional aspartate transaminase/aspartate 4-decarboxylase;


Pssm-ID: 236444  Cd Length: 527  Bit Score: 44.47  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  237 IFFC-SPNNPTGAAATREQLTQLVEFAKKNGS--IIVYDSAYAMYMsdDNPRSIFEipgaeEVAMETA---SFSKYAGFT 310
Cdd:PRK09275 244 ALFLvNPSNPPSVAMSDESLEKIADIVNEKRPdlMIITDDVYGTFV--DDFRSLFA-----VLPYNTIlvySFSKYFGAT 316

                 ....*
gi 75163801  311 GVRLG 315
Cdd:PRK09275 317 GWRLG 321
PRK09082 PRK09082
methionine aminotransferase; Validated
92-323 1.32e-04

methionine aminotransferase; Validated


Pssm-ID: 181642 [Multi-domain]  Cd Length: 386  Bit Score: 44.14  E-value: 1.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801   92 QVISLGIG----DTTEPIPEVITSAMAkkahelstiEGYSGYGAEQGAKPLRAAIAK---TFYGGLGIGDDDVFVSDGAK 164
Cdd:PRK09082  31 GAINLSQGfpdfDGPPYLVEALAYAMA---------AGHNQYPPMTGVAALREAIAAktaRLYGRQYDADSEITVTAGAT 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  165 ----CDISRLqVMFGSNVTiaVQDPSYPAYVDSSVIMG--------QTGQFNTDVQKygnieymrctpengfFPDLSTvG 232
Cdd:PRK09082 102 ealfAAILAL-VRPGDEVI--VFDPSYDSYAPAIELAGgravrvalQPPDFRVDWQR---------------FAAAIS-P 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  233 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNP-RSIFEIPGAEEVAMETASFSKYAGFTG 311
Cdd:PRK09082 163 RTRLIILNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGhASVLRHPELRERAFVVSSFGKTYHVTG 242
                        250
                 ....*....|..
gi 75163801  312 VRLGWTVIPKKL 323
Cdd:PRK09082 243 WKVGYCVAPAAL 254
PLN02187 PLN02187
rooty/superroot1
127-319 1.51e-04

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 43.95  E-value: 1.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  127 SGYGAEQGAKPLRAAIAKTFYGGL--GIGDDDVFVSDGAKCDIsrlQVMFGS----NVTIAVQDPSYPAYVDSSVIMGqt 200
Cdd:PLN02187 102 NSYGPGAGILPARRAVADYMNRDLphKLTPEDIFLTAGCNQGI---EIVFESlarpNANILLPRPGFPHYDARAAYSG-- 176
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  201 gqfnTDVQKYGNIeymrctPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275
Cdd:PLN02187 177 ----LEVRKFDLL------PEKEWEIDLEGIEaiadeNTVAMVVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVY 246
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 75163801  276 AMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVI 319
Cdd:PLN02187 247 DRTIFGDNPFVSMGKFASIVPVLTLAGISKGWVVPGWKIGWIAL 290
PRK08153 PRK08153
pyridoxal phosphate-dependent aminotransferase;
104-358 1.60e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181255  Cd Length: 369  Bit Score: 43.83  E-value: 1.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  104 PIPEVItSAMAKKAHELSTiegysgYG-AEQGAkpLRAAIAktfyGGLGIGDDDVFVS---DGAKCDISRLQVMFGSNVT 179
Cdd:PRK08153  46 PSPSVI-AAMREAAAEIWK------YGdPENHD--LRHALA----AHHGVAPENIMVGegiDGLLGLIVRLYVEPGDPVV 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  180 IAvqDPSYPAyvdssvimgqtgqFNTDVQKYGNIeyMRCTPENGFFPDLS----TVGRTD--IIFFCSPNNPTGAAATRE 253
Cdd:PRK08153 113 TS--LGAYPT-------------FNYHVAGFGGR--LVTVPYRDDREDLDalldAARRENapLVYLANPDNPMGSWHPAA 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  254 QLTQLVEfAKKNGSIIVYDSAY--------AMYMSDDNPRSIfeipgaeevamETASFSKYAGFTGVRLGWTVipkklly 325
Cdd:PRK08153 176 DIVAFIE-ALPETTLLVLDEAYcetapagaAPPIDTDDPNVI-----------RMRTFSKAYGLAGARVGYAI------- 236
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 75163801  326 sdGFP-VAKDFNRIictcFN--GASNISQAGALACL 358
Cdd:PRK08153 237 --GAPgTIKAFDKV----RNhfGMNRIAQAAALAAL 266
PRK12414 PRK12414
putative aminotransferase; Provisional
124-324 2.64e-04

putative aminotransferase; Provisional


Pssm-ID: 183514  Cd Length: 384  Bit Score: 43.24  E-value: 2.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  124 EGYSGYGAEQGAKPLRAAIA---KTFYGGLGIGDDDVFV----SDGAKCDISRLqVMFGSNVTIAvqDPSYPAYVDSSVI 196
Cdd:PRK12414  57 DGHNQYAPMAGIAALREALAektERLYGARYDPASEVTViasaSEGLYAAISAL-VHPGDEVIYF--EPSFDSYAPIVRL 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  197 MGQTGQfntdvqkygnieYMRCTPEnGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVY 271
Cdd:PRK12414 134 QGATPV------------AIKLSPE-DFRVNWDEVAaaitpRTRMIIVNTPHNPSATVFSAADLARLAQLTRNTDIVILS 200
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 75163801  272 DSAYAMYMSDDNP-RSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLL 324
Cdd:PRK12414 201 DEVYEHVVFDGARhHSMARHRELAERSVIVSSFGKSYHVTGWRVGYCLAPAELM 254
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
236-324 7.02e-04

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 41.61  E-value: 7.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75163801  236 IIFFCSPNNPTGAAATREQLTQLVEFAkkngSIIVYDSAY------AMYMSD----DNPrsifeipgaeeVAMETasFSK 305
Cdd:PLN03026 178 LLFLTSPNNPDGSIISDDDLLKILELP----ILVVLDEAYiefstqESRMKWvkkyDNL-----------IVLRT--FSK 240
                         90
                 ....*....|....*....
gi 75163801  306 YAGFTGVRLGWTVIPKKLL 324
Cdd:PLN03026 241 RAGLAGLRVGYGAFPLSII 259
PRK09257 PRK09257
aromatic amino acid transaminase;
227-275 1.80e-03

aromatic amino acid transaminase;


Pssm-ID: 181731  Cd Length: 396  Bit Score: 40.50  E-value: 1.80e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 75163801  227 DLSTVGRTDIIFF---CspNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAY 275
Cdd:PRK09257 165 DLSQAPAGDVVLLhgcC--HNPTGADLTPEQWDELAELLKERGLIPFLDIAY 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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