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Conserved domains on  [gi|81901400|sp|Q8R0Y8|]
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RecName: Full=Mitochondrial coenzyme A transporter SLC25A42; AltName: Full=Solute carrier family 25 member 42

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 1.98e-25

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 103.31  E-value: 1.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400   34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLN--------EGFLSLWRGNSATMVRVIPYAA 105
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPRYSGIVNcfrrvskeQGVLSLWRGNTANVIRYFPTQA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  106 IQFSAHEEYKRILGHY------YGFRGEALppwprlLAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVFI 175
Cdd:PTZ00169  88 FNFAFKDYFKNMFPKYnqktdfWKFFGVNI------LSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  176 RISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLHreYSGRPQpypfERMVFG--------ACAGLIgqsaSYPL 247
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKN----TNILYKwavaqtvtILAGLI----SYPF 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81901400  248 DVVRRR-MQTAGVTGH---QHGSILSTLRSIVREEGaVRGLYKGLSMNWLKG 295
Cdd:PTZ00169 232 DTVRRRmMMMSGRKAKseiQYTGTLDCWKKILKNEG-LGGFFKGAWANVLRG 282
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 1.98e-25

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 103.31  E-value: 1.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400   34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLN--------EGFLSLWRGNSATMVRVIPYAA 105
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPRYSGIVNcfrrvskeQGVLSLWRGNTANVIRYFPTQA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  106 IQFSAHEEYKRILGHY------YGFRGEALppwprlLAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVFI 175
Cdd:PTZ00169  88 FNFAFKDYFKNMFPKYnqktdfWKFFGVNI------LSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  176 RISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLHreYSGRPQpypfERMVFG--------ACAGLIgqsaSYPL 247
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKN----TNILYKwavaqtvtILAGLI----SYPF 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81901400  248 DVVRRR-MQTAGVTGH---QHGSILSTLRSIVREEGaVRGLYKGLSMNWLKG 295
Cdd:PTZ00169 232 DTVRRRmMMMSGRKAKseiQYTGTLDCWKKILKNEG-LGGFFKGAWANVLRG 282
Mito_carr pfam00153
Mitochondrial carrier protein;
29-122 6.26e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 93.49  E-value: 6.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400    29 DHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKE--AFRLLYFTYLNEGFLSLWRGNSATMVRVIPYAAI 106
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 81901400   107 QFSAHEEYKRILGHYY 122
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 34-295 1.98e-25

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 103.31  E-value: 1.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400   34 LSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLN--------EGFLSLWRGNSATMVRVIPYAA 105
Cdd:PTZ00169   8 ATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPRYSGIVNcfrrvskeQGVLSLWRGNTANVIRYFPTQA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  106 IQFSAHEEYKRILGHY------YGFRGEALppwprlLAGALAGTTAASLTYPLDLVRARMAV----TPKEMYSNIFHVFI 175
Cdd:PTZ00169  88 FNFAFKDYFKNMFPKYnqktdfWKFFGVNI------LSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  176 RISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLHreYSGRPQpypfERMVFG--------ACAGLIgqsaSYPL 247
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL--FGNDKN----TNILYKwavaqtvtILAGLI----SYPF 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81901400  248 DVVRRR-MQTAGVTGH---QHGSILSTLRSIVREEGaVRGLYKGLSMNWLKG 295
Cdd:PTZ00169 232 DTVRRRmMMMSGRKAKseiQYTGTLDCWKKILKNEG-LGGFFKGAWANVLRG 282
Mito_carr pfam00153
Mitochondrial carrier protein;
29-122 6.26e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 93.49  E-value: 6.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400    29 DHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKE--AFRLLYFTYLNEGFLSLWRGNSATMVRVIPYAAI 106
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 81901400   107 QFSAHEEYKRILGHYY 122
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
223-315 5.78e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 90.79  E-value: 5.78e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400   223 QPYPFERMVFGACAGLIGQSASYPLDVVRRRMQTAGVTGHQ-HGSILSTLRSIVREEGaVRGLYKGLSMNWLKGPIAVGI 301
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkGRGILDCFKKIYKEEG-IRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....
gi 81901400   302 SFTTFDLMQILLRR 315
Cdd:pfam00153  81 YFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
147-214 2.40e-19

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 81.16  E-value: 2.40e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 81901400   147 SLTYPLDLVRARMAVTP---KEMYSNIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSL 214
Cdd:pfam00153  21 TVTYPLDVVKTRLQVQGgsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 34-287 1.89e-06

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 48.38  E-value: 1.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400   34 LSSLLSGALAGALAKTAVAPLDRTKIIFQvsskrfsAKEAFRLLYFTYLNEGFLslwrgnsATMVRVIPYAAIQFSAHEE 113
Cdd:PTZ00168   4 FHNLVTGALSGVIVDAVLYPIDSIKTNIQ-------AKKSFSFSDIKKLYSGIL-------PTLVGTVPASAFFYCFYEL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  114 YKRILGHYygfRGEALPPWPRLLAGALAGTTAASLTYPLDLVRARMAVTPKemySNIFHVFIRISREEGLKTlYFGFTPT 193
Cdd:PTZ00168  70 SKKLLTEY---RENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGN---ISVLKTIYEITQREGLPS-FLGKSYF 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81901400  194 VLGV--IPYAGLSFFTYESLKS-LHREYSGRPQPYPfeRMVFGACAGLIGQSASY---PLDVVRRRMQTAGvtghqhGSI 267
Cdd:PTZ00168 143 VMIVreIPFDCIQYFLWETLKEkAKKDFGKFSKKYP--SITSAICGGLAGGIAGFlttPVDVIKSRQIIYG------KSY 214

                        250       260
                 ....*....|....*....|
gi 81901400  268 LSTLRSIvrEEGAVRGLYKG 287
Cdd:PTZ00168 215 IETVTEI--AEEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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