RecName: Full=Lysocardiolipin acyltransferase 1; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 8; Short=1-AGP acyltransferase 8; Short=1-AGPAT 8; AltName: Full=Acyl-CoA:lysocardiolipin acyltransferase 1
lysophospholipid acyltransferase family protein( domain architecture ID 10870651)
lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
LPLAT_LCLAT1-like | cd07990 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ... |
93-286 | 8.71e-87 | ||||
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins. : Pssm-ID: 153252 [Multi-domain] Cd Length: 193 Bit Score: 262.17 E-value: 8.71e-87
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Acyltransf_C | pfam16076 | Acyltransferase C-terminus; This domain is found at the C-terminus of several different ... |
271-345 | 1.54e-16 | ||||
Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1. : Pssm-ID: 465006 [Multi-domain] Cd Length: 74 Bit Score: 73.76 E-value: 1.54e-16
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Name | Accession | Description | Interval | E-value | |||||
LPLAT_LCLAT1-like | cd07990 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ... |
93-286 | 8.71e-87 | |||||
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins. Pssm-ID: 153252 [Multi-domain] Cd Length: 193 Bit Score: 262.17 E-value: 8.71e-87
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PLN02510 | PLN02510 | probable 1-acyl-sn-glycerol-3-phosphate acyltransferase |
84-365 | 6.66e-58 | |||||
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase Pssm-ID: 178126 [Multi-domain] Cd Length: 374 Bit Score: 193.76 E-value: 6.66e-58
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PlsC | smart00563 | Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
118-239 | 9.17e-18 | |||||
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family. Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 78.55 E-value: 9.17e-18
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Acyltransf_C | pfam16076 | Acyltransferase C-terminus; This domain is found at the C-terminus of several different ... |
271-345 | 1.54e-16 | |||||
Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1. Pssm-ID: 465006 [Multi-domain] Cd Length: 74 Bit Score: 73.76 E-value: 1.54e-16
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Acyltransferase | pfam01553 | Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
103-261 | 2.77e-14 | |||||
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene. Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 69.23 E-value: 2.77e-14
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PlsC | COG0204 | 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
69-205 | 3.64e-14 | |||||
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 71.19 E-value: 3.64e-14
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AGP_acyltrn | TIGR00530 | 1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ... |
101-205 | 1.99e-05 | |||||
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis] Pssm-ID: 129621 [Multi-domain] Cd Length: 130 Bit Score: 43.87 E-value: 1.99e-05
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Name | Accession | Description | Interval | E-value | ||||||
LPLAT_LCLAT1-like | cd07990 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ... |
93-286 | 8.71e-87 | ||||||
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins. Pssm-ID: 153252 [Multi-domain] Cd Length: 193 Bit Score: 262.17 E-value: 8.71e-87
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PLN02510 | PLN02510 | probable 1-acyl-sn-glycerol-3-phosphate acyltransferase |
84-365 | 6.66e-58 | ||||||
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase Pssm-ID: 178126 [Multi-domain] Cd Length: 374 Bit Score: 193.76 E-value: 6.66e-58
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PLN02380 | PLN02380 | 1-acyl-sn-glycerol-3-phosphate acyltransferase |
57-383 | 1.90e-35 | ||||||
1-acyl-sn-glycerol-3-phosphate acyltransferase Pssm-ID: 178006 [Multi-domain] Cd Length: 376 Bit Score: 134.10 E-value: 1.90e-35
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PlsC | smart00563 | Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
118-239 | 9.17e-18 | ||||||
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family. Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 78.55 E-value: 9.17e-18
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Acyltransf_C | pfam16076 | Acyltransferase C-terminus; This domain is found at the C-terminus of several different ... |
271-345 | 1.54e-16 | ||||||
Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1. Pssm-ID: 465006 [Multi-domain] Cd Length: 74 Bit Score: 73.76 E-value: 1.54e-16
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LPLAT | cd06551 | Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
101-285 | 1.05e-14 | ||||||
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene). Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 72.06 E-value: 1.05e-14
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Acyltransferase | pfam01553 | Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
103-261 | 2.77e-14 | ||||||
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene. Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 69.23 E-value: 2.77e-14
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PlsC | COG0204 | 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
69-205 | 3.64e-14 | ||||||
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 71.19 E-value: 3.64e-14
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LPLAT_AGPAT-like | cd07989 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
99-205 | 6.94e-12 | ||||||
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins. Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 63.83 E-value: 6.94e-12
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PRK14014 | PRK14014 | putative acyltransferase; Provisional |
45-324 | 8.34e-11 | ||||||
putative acyltransferase; Provisional Pssm-ID: 237584 [Multi-domain] Cd Length: 301 Bit Score: 62.56 E-value: 8.34e-11
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AGP_acyltrn | TIGR00530 | 1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ... |
101-205 | 1.99e-05 | ||||||
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis] Pssm-ID: 129621 [Multi-domain] Cd Length: 130 Bit Score: 43.87 E-value: 1.99e-05
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LPLAT_LPCAT1-like | cd07991 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ... |
118-205 | 3.26e-03 | ||||||
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences. Pssm-ID: 153253 [Multi-domain] Cd Length: 211 Bit Score: 38.74 E-value: 3.26e-03
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Blast search parameters | ||||
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