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Conserved domains on  [gi|74710067|sp|Q6R2W3|]
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RecName: Full=SCAN domain-containing protein 3; AltName: Full=Transposon-derived Buster4 transposase-like protein; AltName: Full=Zinc finger BED domain-containing protein 9

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SCAN smart00431
leucine rich region;
48-160 1.59e-70

leucine rich region;


:

Pssm-ID: 128708 [Multi-domain]  Cd Length: 113  Bit Score: 231.04  E-value: 1.59e-70
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067      48 RELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLL 127
Cdd:smart00431    1 PEIFRQRFRQFRYQETSGPREALSRLRELCRQWLRPELHTKEQILELLVLEQFLTILPGELQAWVREHHPESGEEAVTLL 80

                            90       100       110
                    ....*....|....*....|....*....|...
gi 74710067     128 EDLERELDEPRQQVSQGTYGQEVSMEEMIPLDS 160
Cdd:smart00431   81 EDLERELDEPGQQVSAHVHGQEVLLEKMVPLGA 113
DUF4371 super family cl46273
Domain of unknown function (DUF4371);
862-978 3.60e-04

Domain of unknown function (DUF4371);


The actual alignment was detected with superfamily member pfam14291:

Pssm-ID: 480613  Cd Length: 236  Bit Score: 43.76  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067    862 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 935
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 74710067    936 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 978
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT super family cl05324
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1248-1295 9.06e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


The actual alignment was detected with superfamily member pfam05699:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.47  E-value: 9.06e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 74710067   1248 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1295
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Name Accession Description Interval E-value
SCAN smart00431
leucine rich region;
48-160 1.59e-70

leucine rich region;


Pssm-ID: 128708 [Multi-domain]  Cd Length: 113  Bit Score: 231.04  E-value: 1.59e-70
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067      48 RELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLL 127
Cdd:smart00431    1 PEIFRQRFRQFRYQETSGPREALSRLRELCRQWLRPELHTKEQILELLVLEQFLTILPGELQAWVREHHPESGEEAVTLL 80

                            90       100       110
                    ....*....|....*....|....*....|...
gi 74710067     128 EDLERELDEPRQQVSQGTYGQEVSMEEMIPLDS 160
Cdd:smart00431   81 EDLERELDEPGQQVSAHVHGQEVLLEKMVPLGA 113
SCAN pfam02023
SCAN domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found ...
 49-136 1.44e-55

SCAN domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found in several pfam00096 proteins. The domain has been shown to be able to mediate homo- and hetero-oligomerization.


Pssm-ID: 460417 [Multi-domain]  Cd Length: 89  Bit Score: 187.31  E-value: 1.44e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067     49 ELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLLE 128
Cdd:pfam02023    2 EASRQRFRQFCYQEAEGPREALSQLRELCHQWLRPEKHTKEQILELLVLEQFLTILPEEIQSWVREHHPESGEEAVALAE 81


                   ....*...
gi 74710067    129 DLERELDE 136
Cdd:pfam02023   82 DLLLERGE 89
SCAN cd07936
SCAN oligomerization domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 ...
 49-132 4.45e-45

SCAN oligomerization domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found in several vertebrate proteins that contain C2H2 zinc finger motifs, many of which may be transcription factors playing roles in cell survival and differentiation. This protein-interaction domain is able to mediate homo- and hetero-oligomerization of SCAN-containing proteins. Some SCAN-containing proteins, including those of lower vertebrates, do not contain zinc finger motifs. It has been noted that the SCAN domain resembles a domain-swapped version of the C-terminal domain of the HIV capsid protein. This domain model features elements common to the three general groups of SCAN domains (SCAN-A1, SCAN-A2, and SCAN-B). The SCAND1 protein is truncated at the C-terminus with respect to this model, the SCAND2 protein appears to have a truncated central helix.


Pssm-ID: 153421  Cd Length: 85  Bit Score: 157.04  E-value: 4.45e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067   49 ELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLLE 128
Cdd:cd07936    2 ETYRQRFRAFQYQEASGPREALQRLRELCRQWLRPEIHTKEQILELLVLEQFLIILPPEVQAWVRERKPESGEEAATLAE 81


                 ....
gi 74710067  129 DLER 132
Cdd:cd07936   82 DLLA 85
DUF4371 pfam14291
Domain of unknown function (DUF4371);
862-978 3.60e-04

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 43.76  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067    862 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 935
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 74710067    936 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 978
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1248-1295 9.06e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.47  E-value: 9.06e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 74710067   1248 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1295
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Name Accession Description Interval E-value
SCAN smart00431
leucine rich region;
48-160 1.59e-70

leucine rich region;


Pssm-ID: 128708 [Multi-domain]  Cd Length: 113  Bit Score: 231.04  E-value: 1.59e-70
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067      48 RELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLL 127
Cdd:smart00431    1 PEIFRQRFRQFRYQETSGPREALSRLRELCRQWLRPELHTKEQILELLVLEQFLTILPGELQAWVREHHPESGEEAVTLL 80

                            90       100       110
                    ....*....|....*....|....*....|...
gi 74710067     128 EDLERELDEPRQQVSQGTYGQEVSMEEMIPLDS 160
Cdd:smart00431   81 EDLERELDEPGQQVSAHVHGQEVLLEKMVPLGA 113
SCAN pfam02023
SCAN domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found ...
 49-136 1.44e-55

SCAN domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found in several pfam00096 proteins. The domain has been shown to be able to mediate homo- and hetero-oligomerization.


Pssm-ID: 460417 [Multi-domain]  Cd Length: 89  Bit Score: 187.31  E-value: 1.44e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067     49 ELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLLE 128
Cdd:pfam02023    2 EASRQRFRQFCYQEAEGPREALSQLRELCHQWLRPEKHTKEQILELLVLEQFLTILPEEIQSWVREHHPESGEEAVALAE 81


                   ....*...
gi 74710067    129 DLERELDE 136
Cdd:pfam02023   82 DLLLERGE 89
SCAN cd07936
SCAN oligomerization domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 ...
 49-132 4.45e-45

SCAN oligomerization domain; The SCAN domain (named after SRE-ZBP, CTfin51, AW-1 and Number 18 cDNA) is found in several vertebrate proteins that contain C2H2 zinc finger motifs, many of which may be transcription factors playing roles in cell survival and differentiation. This protein-interaction domain is able to mediate homo- and hetero-oligomerization of SCAN-containing proteins. Some SCAN-containing proteins, including those of lower vertebrates, do not contain zinc finger motifs. It has been noted that the SCAN domain resembles a domain-swapped version of the C-terminal domain of the HIV capsid protein. This domain model features elements common to the three general groups of SCAN domains (SCAN-A1, SCAN-A2, and SCAN-B). The SCAND1 protein is truncated at the C-terminus with respect to this model, the SCAND2 protein appears to have a truncated central helix.


Pssm-ID: 153421  Cd Length: 85  Bit Score: 157.04  E-value: 4.45e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067   49 ELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLLE 128
Cdd:cd07936    2 ETYRQRFRAFQYQEASGPREALQRLRELCRQWLRPEIHTKEQILELLVLEQFLIILPPEVQAWVRERKPESGEEAATLAE 81


                 ....
gi 74710067  129 DLER 132
Cdd:cd07936   82 DLLA 85
DUF4371 pfam14291
Domain of unknown function (DUF4371);
862-978 3.60e-04

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 43.76  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74710067    862 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 935
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 74710067    936 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 978
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1248-1295 9.06e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.47  E-value: 9.06e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 74710067   1248 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1295
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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