NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|81360091|sp|Q5PFG7|]
View 

RecName: Full=NAD kinase; AltName: Full=ATP-dependent NAD kinase

Protein Classification

NAD(+) kinase( domain architecture ID 10011922)

NAD(+) kinase catalyzes specifically the phosphorylation on the 2'-hydroxyl of the adenosine moiety of NAD to yield NADP, and is involved in regulating the intracellular balance of NAD and NADP

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


:

Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 609.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    1 MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   81 RTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  161 EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81360091  241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 609.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    1 MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   81 RTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  161 EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81360091  241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-290 1.49e-136

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 386.80  E-value: 1.49e-136
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   5 FKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAhelqlknVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLA 84
Cdd:COG0061   1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  85 RYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEV 164
Cdd:COG0061  74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091 165 YIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISC 244
Cdd:COG0061 154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRPAVLVA 233

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*.
gi 81360091 245 DSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKK 290
Cdd:COG0061 234 DGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-271 2.60e-53

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 169.79  E-value: 2.60e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   146 INEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINS 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 81360091   226 SSTIRLRFShRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIH 271
Cdd:pfam20143  81 SSKLRIRVL-SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-292 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 609.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    1 MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   81 RTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  161 EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDL 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPNRSDL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 81360091  241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF 292
Cdd:PRK03378 241 EISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
ppnK PRK02231
NAD(+) kinase;
22-291 5.53e-140

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 395.33  E-value: 5.53e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   22 THEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFL 101
Cdd:PRK02231   1 MHKNLFHWLKERGYQVLVEKEIAEQLNLPENHLASLEEIGQRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  102 TDLDPDNALQQLSDVLE-GRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLI 180
Cdd:PRK02231  81 TDIDPKNAYEQLEACLErGEFFVEERFLLEAKIERNGKIIATSNALNEVVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  181 ISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFS-HRRSDLEISCDSQIALPIQEGEDVL 259
Cdd:PRK02231 161 ISTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKISLRFAeYNTPQLEVSCDSQIALPFTPDDRVH 240

                        250       260       270
                 ....*....|....*....|....*....|..
gi 81360091  260 IRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKL 291
Cdd:PRK02231 241 VQKSPDKLRLLHLKNYNYYNVLSSKLGWLKKL 272
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-290 1.49e-136

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 386.80  E-value: 1.49e-136
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   5 FKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAhelqlknVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLA 84
Cdd:COG0061   1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  85 RYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEV 164
Cdd:COG0061  74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091 165 YIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISC 244
Cdd:COG0061 154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRPAVLVA 233

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*.
gi 81360091 245 DSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKK 290
Cdd:COG0061 234 DGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
ppnK PRK01231
NAD(+) kinase;
2-291 1.16e-134

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 382.77  E-value: 1.16e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    2 NNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAAR 81
Cdd:PRK01231   1 MPSFRNIGLIGRLGSSSVVETLRRLKDFLLDRGLEVILDEETAEVLPGHGLQTVSRKLLGEVCDLVIVVGGDGSLLGAAR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   82 TLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIE 161
Cdd:PRK01231  81 ALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEVRRGGEVIGQGDALNDVVLHPGKSTRMIE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  162 FEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFS-HRRSDL 240
Cdd:PRK01231 161 FELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISkDNRTYP 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 81360091  241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKL 291
Cdd:PRK01231 241 RVSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLDYNYYETCRTKLGWGSRL 291
ppnK PRK02155
NAD kinase;
1-288 1.67e-110

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 321.51  E-value: 1.67e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    1 MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAA 80
Cdd:PRK02155   1 MKSQFKTVALIGRYQTPGIAEPLESLAAFLAKRGFEVVFEADTARNIGLTGYPALTPEEIGARADLAVVLGGDGTMLGIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   81 RTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI 160
Cdd:PRK02155  81 RQLAPYGVPLIGINHGRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVVRDGEPIFHALAFNDVVVNRSGFSGMV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  161 EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFsHRRSDL 240
Cdd:PRK02155 161 ELRVSVDGRFMYNQRSDGLIVATPTGSTAYALSAGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQI-VGGRDV 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 81360091  241 EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWS 288
Cdd:PRK02155 240 SVNFDMQSLTSLELGDRIEVRRSPHTVRFLHPVGYSYYATLRKKLHWN 287
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-291 4.81e-85

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 257.09  E-value: 4.81e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    1 MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHEL-----QLKNVPTGTLAEIGQQADLAVVVGGDGN 75
Cdd:PRK04539   1 MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGciytqDTVGCHIVNKTELGQYCDLVAVLGGDGT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   76 MLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGK 155
Cdd:PRK04539  81 FLSVAREIAPRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERALALNDAVLSRGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  156 VAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSh 235
Cdd:PRK04539 161 AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVT- 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 81360091  236 RRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKL 291
Cdd:PRK04539 240 QGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQL 295
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 8-287 6.49e-66

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 207.85  E-value: 6.49e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    8 IGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQ----IAHELQLKNVPTGTLAEIG--QQADLAVVVGGDGNMLGAAR 81
Cdd:PRK01911   3 IAIFGQTYQESASPYIQELFDELEERGAEVLIEEKfldfLKQDLKFHPSYDTFSDNEEldGSADMVISIGGDGTFLRTAT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   82 TLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQvCQQDRQKRISTAINEVVLHPGKVAHMIE 161
Cdd:PRK01911  83 YVGNSNIPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLE-SNPKLFGELNFALNEIAILKRDTSSMIT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  162 FEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLE 241
Cdd:PRK01911 162 VHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDDTEITLEVESRSDNFL 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 81360091  242 ISCDSQIALpIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGW 287
Cdd:PRK01911 242 VSLDSRSET-VDNGTELTIKKADFTIKLVELNNHSFLKTLRNKLLW 286
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
29-286 1.82e-57

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 193.41  E-value: 1.82e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   29 WLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDN 108
Cdd:PRK14076 314 YLDSKGIPYELESFLYNKLKNRLNEECNLIDDIEEISHIISIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKEE 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  109 ALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGST 188
Cdd:PRK14076 394 IFKAIDSIISGEYEIEKRTKLSGFILKDGHQNILPSALNEVVITTKNPAKMLHFEVYVNGELVEEVRADGIIISTPTGST 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  189 AYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEIscDSQIALPIQEGEDVLIRRCDYHLN 268
Cdd:PRK14076 474 AYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSANSEIKIKLLKKSALVVI--DGSIEFEAKKGDEIIFRKSDSYAY 551

                        250
                 ....*....|....*...
gi 81360091  269 LIhpKDYSYFNTLSTKLG 286
Cdd:PRK14076 552 FV--KGDNFYNKLKKLSL 567
ppnK PRK02645
NAD(+) kinase;
41-287 2.01e-56

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 183.96  E-value: 2.01e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   41 QQIAHELQLKNV-----PTGT--------LAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGIN-RGNLGFLT---- 102
Cdd:PRK02645  22 ERCAKQLEARGCkvlmgPSGPkdnpypvfLASASELIDLAIVLGGDGTVLAAARHLAPHDIPILSVNvGGHLGFLThprd 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  103 DLDPDNALQQLsdvLEGRYISEKRFLLEAQVCQQDR--QKRIS---TAINEVVLHPGKVAHMI--EFEVYIDETFAFSQR 175
Cdd:PRK02645 102 LLQDESVWDRL---QEDRYAIERRMMLQARVFEGDRsnEEPVSesyYALNDFYLKPASEDRSPtcILELEIDGEVVDQYQ 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  176 SDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRfSHRRSDLEISC--DSQIALPIQ 253
Cdd:PRK02645 179 GDGLIVSTPTGSTAYTMAAGGPILHPGIDAIIVTPICPMSLSSRPIVIPPGSRVVIW-PLGDYDLNIKLwkDGVLATSIW 257

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 81360091  254 EGEDVLIRRCDYH-LNLIHPKDYSYFNTLSTKLGW 287
Cdd:PRK02645 258 PGQRCVIQKARHPaKFIILEESYSYYRTLREKLHW 292
ppnK PRK03708
NAD(+) kinase;
8-233 3.18e-56

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 182.60  E-value: 3.18e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    8 IGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHEL-QLKNVPTGTLAEIgqQADLAVVVGGDGNMLgAARTLARY 86
Cdd:PRK03708   3 FGIVARRDKEEALKLAYRVYDFLKVSGYEVVVDSETYEHLpEFSEEDVLPLEEM--DVDFIIAIGGDGTIL-RIEHKTKK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   87 DINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDrqkrISTAINEVVLHPGKVAHMIEFEVYI 166
Cdd:PRK03708  80 DIPILGINMGTLGFLTEVEPEETFFALSRLLEGDYFIDERIKLRVYINGEN----VPDALNEVVILTGIPGKIIHLKYYV 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 81360091  167 DETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRF 233
Cdd:PRK03708 156 DGELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVKL 222
ppnK PRK02649
NAD(+) kinase;
7-287 1.08e-54

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 179.40  E-value: 1.08e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091    7 CIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIV-------------EQQIAHELQLKNVPTGtlaeIGQQADLAVVVGGD 73
Cdd:PRK02649   3 KAGIIYNDGKPLAVRTAEELQDKLEAAGWEVVRasssggilgyanpDQPVCHTGIDQLVPPG----FDSSMKFAIVLGGD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   74 GNMLGAARTLARYDINVIGINRGNLGFLT-----DLDPdnALQQlsdVLEGRYISEKRFLLEAQVCQQDRQKRISTAINE 148
Cdd:PRK02649  79 GTVLSAARQLAPCGIPLLTINTGHLGFLTeaylnQLDE--AIDQ---VLAGQYTIEERTMLTVSVMRGDQLRWEALSLNE 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  149 VVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSST 228
Cdd:PRK02649 154 MVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPICPHSLASRALVFSDSEP 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 81360091  229 IRLrFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGW 287
Cdd:PRK02649 234 VTV-FPATPERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDPEFFRVLREKLGW 291
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-271 2.60e-53

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 169.79  E-value: 2.60e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   146 INEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINS 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 81360091   226 SSTIRLRFShRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIH 271
Cdd:pfam20143  81 SSKLRIRVL-SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
pnk PRK14077
NAD(+) kinase;
36-289 9.41e-51

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 168.81  E-value: 9.41e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   36 EVIVEQQIAHELqlkNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSD 115
Cdd:PRK14077  40 EILLEKESAEIL---DLPGYGLDELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  116 VLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAG 195
Cdd:PRK14077 117 FFQGEFEIEKPYMLSVFLEKKQGKILEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTAYNMSAN 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  196 GPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRfshRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDY 275
Cdd:PRK14077 197 GPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFK---TKSDCILCIDGQDRYKMNDFKSIKVGLSDKNVALIRHKNR 273

                        250
                 ....*....|....
gi 81360091  276 SYFNTLSTKLGWSK 289
Cdd:PRK14077 274 DYFQILKEKLHWGN 287
ppnK PRK01185
NAD(+) kinase;
30-262 1.58e-43

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 149.58  E-value: 1.58e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   30 LCDQGYEVIVEQQIAHELQLKNVptgTLAEIgqQADLAVVVGGDGNMLgaaRTLARYDINVIGINRGNLGFLTDLDPDNA 109
Cdd:PRK01185  24 LLPPDWEIIYEMEAAKALGMDGL---DIEEI--NADVIITIGGDGTIL---RTLQRAKGPILGINMGGLGFLTEIEIDEV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  110 LQQLSDVLEGRYISEKRFLLEAQVcqqdRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTA 189
Cdd:PRK01185  96 GSAIKKLIRGEYFIDERMKLKVYI----NGERLEDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTS 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81360091  190 YSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEIsCDSQIALPIQEGEDVLIRR 262
Cdd:PRK01185 172 YSSSAGGPILLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSLLI-LDGQYEYKISKGDTVEISK 243
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 10-264 1.22e-42

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 148.14  E-value: 1.22e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   10 IVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIG---------QQADLAVVVGGDGNMLGAA 80
Cdd:PRK03372  10 LVAHTGRDEATEAARRVAKQLGDAGIGVRVLDAEAVDLGATHPAPDDFRAMEvvdadpdaaDGCELVLVLGGDGTILRAA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   81 RtLAR-YDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVcQQDRQKRIST-AINEVVLHPGKVAH 158
Cdd:PRK03372  90 E-LARaADVPVLGVNLGHVGFLAEAEAEDLDEAVERVVDRDYRVEERMTLDVTV-RVGGEIVWRGwALNEASLEKADREG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  159 MIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRS 238
Cdd:PRK03372 168 MLEVVLEVDGRPVSSFGCDGVLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVEILADTS 247

                        250       260
                 ....*....|....*....|....*...
gi 81360091  239 DLEISCDS--QIALPiqEGEDVLIRRCD 264
Cdd:PRK03372 248 DAVLWCDGrrSVDLP--PGARVEVRRGA 273
pnk PRK14075
NAD(+) kinase;
64-291 1.38e-42

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 146.80  E-value: 1.38e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   64 ADLAVVVGGDGNMLGAARtlaRYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDrqkriS 143
Cdd:PRK14075  42 ADLIIVVGGDGTVLKAAK---KVGTPLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLKIESELGN-----H 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  144 TAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVI 223
Cdd:PRK14075 114 LALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGPIILPNCEVFEITPIAPQFLATRSIVI 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 81360091  224 NSSSTIRLRfshrrsdleisCDSQIALpIQEGEDV------LIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKL 291
Cdd:PRK14075 194 PSNEKVTVE-----------SQRDINL-IVDGVLVgktnriTVKKSRRYVRILRPKDYDFVTVIKEKLGYGRRI 255
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 8-118 1.38e-31

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 114.00  E-value: 1.38e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091     8 IGIVGHPRHPTALTTHEMLYRWLCD-QGYEVIVEQQIAHELQL----------------KNVPTGTLAEIGQQADLAVVV 70
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDrLGITVTVEEKMGESLAFaagdrpevigclkkvvDDTRRATRAFADAGVDLIIVL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 81360091    71 GGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLE 118
Cdd:pfam01513  81 GGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 24-235 4.34e-30

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 118.40  E-value: 4.34e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   24 EMLyRWLCDQ-GYEVIVEQQIAHELQLKN-----VPT----GTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGI 93
Cdd:PLN02935 214 EMV-RWLREQkGLNIYVEPRVKKELLSESsyfnfVQTwedeKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPF 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   94 NRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRIST-----AINEVVLHPGKVAHMIEFEVYIDE 168
Cdd:PLN02935 293 SMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAAKNEYETeepilVLNEVTIDRGISSFLTNLECYCDN 372

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 81360091  169 TFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSH 235
Cdd:PLN02935 373 SFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPF 439
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 63-199 3.04e-23

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 95.27  E-value: 3.04e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   63 QADLAVVVGGDGNMLgaaRTLARY---DINVIGINRGNLGFL-TDLDPDNALQQLSDVlegryISEKRFLLEAQVCQQDR 138
Cdd:PRK04761  25 EADVIVALGGDGFML---QTLHRYmnsGKPVYGMNRGSVGFLmNEYSEDDLLERIAAA-----EPTVLHPLRMTATDVSG 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81360091  139 QKRISTAINEV-VLHPGKVAhmIEFEVYIDETFAFSQ-RSDGLIISTPTGSTAYSLSAGGPIL 199
Cdd:PRK04761  97 EVHEALAINEVsLFRQTRQA--AKLRISIDGKVRMEElVCDGVLVATPAGSTAYNLSAHGPIL 157
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 65-247 3.06e-23

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 95.66  E-value: 3.06e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   65 DLAVVVGGDGNMLGAartLARY-----DINVIGINRGNLGFLTDLDPDNaLQQLSDVL---EGRYISEKrfLLEAQVCQQ 136
Cdd:PRK04885  37 DIVISVGGDGTLLSA---FHRYenqldKVRFVGVHTGHLGFYTDWRPFE-VDKLVIALakdPGQVVSYP--LLEVKITYE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  137 DRQKRISTAINEVVLHpgKVAHMIEFEVYID----ETFafsqRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPM- 211
Cdd:PRK04885 111 DGEKEKYLALNEATIK--RIEGTLVADVYINgvlfERF----RGDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIa 184

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 81360091  212 ------FpHTLSArPLVINSSSTIRLRfSHRRSDLEISCDSQ 247
Cdd:PRK04885 185 sinnrvF-RTLGS-PLILPKHHTITLK-PVNDDDYQITVDHL 223
PLN02727 PLN02727
NAD kinase
 62-291 1.09e-21

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 94.95  E-value: 1.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   62 QQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDV------LEGRYISeKRFLLEAQVCQ 135
Cdd:PLN02727 742 ERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVihgnntLDGVYIT-LRMRLRCEIFR 820

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  136 QDRQ--KRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFP 213
Cdd:PLN02727 821 NGKAmpGKVFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICP 900

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  214 HTLSARPLVINSSSTIRLRF-SHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS--YFNTLSTKLGWSKK 290
Cdd:PLN02727 901 HSLSFRPVILPDSARLELKIpDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTgdWFRSLIRCLNWNER 980


                 .
gi 81360091  291 L 291
Cdd:PLN02727 981 L 981
ppnK PRK03501
NAD kinase;
62-279 4.08e-19

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 84.64  E-value: 4.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   62 QQADLAVVVGGDGNMLGAAR-TLARYDINVIGINR-GNLGFLTDL---DPDNALQQLS-DVLEGRyiseKRFLLEAQVCQ 135
Cdd:PRK03501  38 KNANIIVSIGGDGTFLQAVRkTGFREDCLYAGISTkDQLGFYCDFhidDLDKMIQAITkEEIEVR----KYPTIEVTVDG 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  136 qdrqkriSTAI---NEVVLHPGKVAHMIeFEVYID----ETFafsqRSDGLIISTPTGSTAYSLSAGGPILTPsldaitL 208
Cdd:PRK03501 114 -------STSFyclNEFSIRSSIIKTFV-IDVYIDdlhfETF----RGDGMVVSTPTGSTAYNKSVRGAVVDP------L 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  209 VPMFP------------HTLSArPLVINSSSTIRLRFSHRRSDLE-ISCDSQiALPIQEGEDVLIRRCDYHLNLIHPKDY 275
Cdd:PRK03501 176 IPCFQvselaslnnntyRTLGS-PFILSHERKLTLKIVQDGNDYPiIGMDNE-ALSIKHVEKIDIRLSDKQIKTVKLKDN 253


                 ....
gi 81360091  276 SYFN 279
Cdd:PRK03501 254 SFWE 257
ppnK PRK00561
NAD(+) kinase;
49-213 1.09e-16

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 77.99  E-value: 1.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   49 LKNVPTGTLAEIgQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLT-----DLDpDNALQQLsDVLEGRYIS 123
Cdd:PRK00561  20 LKKVLKKKLAVE-DGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTsfnetDLD-QNFANKL-DQLKFTQID 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  124 ekrfLLEAQVCQQDRQKRISTAINEVVLHPgkvahmieFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSL 203
Cdd:PRK00561  97 ----LLEVQIDDQIHLVLNELAVYTNTAYP--------INIFIDNEFWEKYRGSGLLIGPRTGSTALAKSAKGAVIFPRI 164

                        170
                 ....*....|
gi 81360091  204 DAITLVPMFP 213
Cdd:PRK00561 165 DVIQIIELNP 174
PLN02929 PLN02929
NADH kinase
 64-276 2.05e-10

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 60.44  E-value: 2.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091   64 ADLAVVVGGDGNMLGAARTLaRYDINVIGIN------------------RGNLGFLTDLDPDNALQQLSDVLEGRYISEK 125
Cdd:PLN02929  65 VDLVVAVGGDGTLLQASHFL-DDSIPVLGVNsdptqkdeveeysdefdaRRSTGHLCAATAEDFEQVLDDVLFGRLKPTE 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  126 RflleaqvcqqdrqKRISTAINEVVL-----------HPgKVAHMIEFEVYI-----DETFAFSQRSDGLIISTPTGSTA 189
Cdd:PLN02929 144 L-------------SRISTVVNGTLLetpalndvliaHP-SPAAVSRFSFRVgrqggSSGPLINVRSSGLRVSTAAGSTA 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81360091  190 YSLSAGG---PILTPSLDAITLVPMFPHTLSARPL--VINSSSTIRLRFSHRRSDLEIScDSQIALPIQEGEDVLIRRCD 264
Cdd:PLN02929 210 AMLSAGGfpmPLLSRDLQYMVREPISPGHPPKSLMhgFYKPGQHMQVRWNSRKGTIYID-GSHVMHSIKLGDTIEISSDA 288

                        250
                 ....*....|..
gi 81360091  265 YHLNLIHPKDYS 276
Cdd:PLN02929 289 PPLKVFLSHWFL 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH