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Conserved domains on  [gi|74743052|sp|Q5MJ10|]
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RecName: Full=Sperm protein associated with the nucleus on the X chromosome N2; AltName: Full=Nuclear-associated protein SPAN-Xn2; Short=SPANX-N2; AltName: Full=SPANX family member N2

Protein Classification

SPAN-X domain-containing protein( domain architecture ID 10538540)

SPAN-X domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SPAN-X pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; This family contains human ...
 1-95 6.72e-36

Sperm protein associated with nucleus, mapped to X chromosome; This family contains human sperm proteins associated with the nucleus and mapped to the X chromosome (SPAN-X) (approximately 100 residues long). SPAN-X proteins are cancer-testis antigens (CTAs), and thus represent potential targets for cancer immunotherapy because they are widely distributed in tumours but not in normal tissues, except testes. They are highly insoluble, acidic, and polymorphic.


:

Pssm-ID: 400025  Cd Length: 94  Bit Score: 120.42  E-value: 6.72e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     1 MEQPTSSTNGEKRKSPCESNNKkNDEMQEAPNRVLAPKQSLQKTKTIEYLTIIVYYYRKHTKINSNQLEKDQSRENSINP 80
Cdd:pfam07458   1 MEQPTSSTNGEKRKSPCDSNNA-NDEMQETPNRDLAPQPSLKKTKTSEYSTILVVRYRKNKKISSNQLENDQSRENSINP 79

                          90
                  ....*....|....*
gi 74743052    81 VQEEEDEGLDSAEGS 95
Cdd:pfam07458  80 LQMEEEEFMEIREES 94
CobT2 super family cl34772
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 89-178 1.72e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


The actual alignment was detected with superfamily member COG4547:

Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 52.87  E-value: 1.72e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052  89 LDSAEGSSQEDEDLDSSEGssqEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDldsSEGSSQEDEDLDPPEGSSQEDEDLD 168
Cdd:COG4547 205 LDLAEELGEDEDEEDEDDE---DDSGEQEEDEEDGEDEDEESDEGAEAEDAE---ASGDDAEEGESEAAEAESDEMAEEA 278

                        90
                ....*....|
gi 74743052 169 SSEGSSQEGG 178
Cdd:COG4547 279 EGEDSEEPGE 288
 
Name Accession Description Interval E-value
SPAN-X pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; This family contains human ...
 1-95 6.72e-36

Sperm protein associated with nucleus, mapped to X chromosome; This family contains human sperm proteins associated with the nucleus and mapped to the X chromosome (SPAN-X) (approximately 100 residues long). SPAN-X proteins are cancer-testis antigens (CTAs), and thus represent potential targets for cancer immunotherapy because they are widely distributed in tumours but not in normal tissues, except testes. They are highly insoluble, acidic, and polymorphic.


Pssm-ID: 400025  Cd Length: 94  Bit Score: 120.42  E-value: 6.72e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     1 MEQPTSSTNGEKRKSPCESNNKkNDEMQEAPNRVLAPKQSLQKTKTIEYLTIIVYYYRKHTKINSNQLEKDQSRENSINP 80
Cdd:pfam07458   1 MEQPTSSTNGEKRKSPCDSNNA-NDEMQETPNRDLAPQPSLKKTKTSEYSTILVVRYRKNKKISSNQLENDQSRENSINP 79

                          90
                  ....*....|....*
gi 74743052    81 VQEEEDEGLDSAEGS 95
Cdd:pfam07458  80 LQMEEEEFMEIREES 94
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 89-178 1.72e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 52.87  E-value: 1.72e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052  89 LDSAEGSSQEDEDLDSSEGssqEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDldsSEGSSQEDEDLDPPEGSSQEDEDLD 168
Cdd:COG4547 205 LDLAEELGEDEDEEDEDDE---DDSGEQEEDEEDGEDEDEESDEGAEAEDAE---ASGDDAEEGESEAAEAESDEMAEEA 278

                        90
                ....*....|
gi 74743052 169 SSEGSSQEGG 178
Cdd:COG4547 279 EGEDSEEPGE 288
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 83-172 1.73e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 44.15  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    83 EEEDEGLDSAEGSSQEDEDLDSSEgssQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSE----------GSSQEDE 152
Cdd:pfam04931 626 RENPEGQQELFEDEDEDEEDDDEE---EDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDelraklaealGEHGDDA 702

                          90       100
                  ....*....|....*....|
gi 74743052   153 DldppEGSSQEDEDLDSSEG 172
Cdd:pfam04931 703 D----DDDSDSDEDMDDEQM 718
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 69-179 1.25e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 38.82  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     69 EKDQSRENSINPVQEEEDEGLDSAEGSSQ-EDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSS--EGSSQEDEDLDSSE 145
Cdd:TIGR00927  658 ENGEESGGEAEQEGETETKGENESEGEIPaERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETeaEGTEDEGEIETGEE 737

                           90       100       110
                   ....*....|....*....|....*....|....
gi 74743052    146 GSSQEDEDLDPPEGSSQEDEDLDSSEGSSQEGGE 179
Cdd:TIGR00927  738 GEEVEDEGEGEAEGKHEVETEGDRKETEHEGETE 771
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 71-171 1.74e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 38.04  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052   71 DQSRENSINPVQEEEDEglDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSS-----------QEDEDLDSSEGSSQEDE 139
Cdd:PRK13108 327 DDVAEAVKAEVAEVTDE--VAAESVVQVADRDGESTPAVEETSEADIEREQPgdlagqapaahQVDAEAASAAPEEPAAL 404

                         90       100       110
                 ....*....|....*....|....*....|..
gi 74743052  140 DLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSE 171
Cdd:PRK13108 405 ASEAHDETEPEVPEKAAPIPDPAKPDELAVAG 436
 
Name Accession Description Interval E-value
SPAN-X pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; This family contains human ...
 1-95 6.72e-36

Sperm protein associated with nucleus, mapped to X chromosome; This family contains human sperm proteins associated with the nucleus and mapped to the X chromosome (SPAN-X) (approximately 100 residues long). SPAN-X proteins are cancer-testis antigens (CTAs), and thus represent potential targets for cancer immunotherapy because they are widely distributed in tumours but not in normal tissues, except testes. They are highly insoluble, acidic, and polymorphic.


Pssm-ID: 400025  Cd Length: 94  Bit Score: 120.42  E-value: 6.72e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     1 MEQPTSSTNGEKRKSPCESNNKkNDEMQEAPNRVLAPKQSLQKTKTIEYLTIIVYYYRKHTKINSNQLEKDQSRENSINP 80
Cdd:pfam07458   1 MEQPTSSTNGEKRKSPCDSNNA-NDEMQETPNRDLAPQPSLKKTKTSEYSTILVVRYRKNKKISSNQLENDQSRENSINP 79

                          90
                  ....*....|....*
gi 74743052    81 VQEEEDEGLDSAEGS 95
Cdd:pfam07458  80 LQMEEEEFMEIREES 94
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 89-178 1.72e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 52.87  E-value: 1.72e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052  89 LDSAEGSSQEDEDLDSSEGssqEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDldsSEGSSQEDEDLDPPEGSSQEDEDLD 168
Cdd:COG4547 205 LDLAEELGEDEDEEDEDDE---DDSGEQEEDEEDGEDEDEESDEGAEAEDAE---ASGDDAEEGESEAAEAESDEMAEEA 278

                        90
                ....*....|
gi 74743052 169 SSEGSSQEGG 178
Cdd:COG4547 279 EGEDSEEPGE 288
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 67-168 1.82e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 52.87  E-value: 1.82e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052  67 QLEKDQSRENSINPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDldsSEGSSQEDEDLDSSEGSSQEDEDLDSSEG 146
Cdd:COG4547 206 DLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAE---ASGDDAEEGESEAAEAESDEMAEEAEGED 282

                        90       100
                ....*....|....*....|..
gi 74743052 147 SSQEDEDLDPPEGSSQEDEDLD 168
Cdd:COG4547 283 SEEPGEPWRPNAPPPDDPADPD 304
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 100-180 2.14e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 52.49  E-value: 2.14e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052 100 EDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSEGSSQEGGE 179
Cdd:COG4547 203 RDLDLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEGESEAAEAESDEMAEEAEGED 282


                .
gi 74743052 180 D 180
Cdd:COG4547 283 S 283
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 101-180 7.49e-08

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 50.95  E-value: 7.49e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052 101 DLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSEGSSQEGGED 180
Cdd:COG4547 206 DLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEGESEAAEAESDEMAEEAEGEDSEE 285
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 83-172 1.73e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 44.15  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    83 EEEDEGLDSAEGSSQEDEDLDSSEgssQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSE----------GSSQEDE 152
Cdd:pfam04931 626 RENPEGQQELFEDEDEDEEDDDEE---EDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDelraklaealGEHGDDA 702

                          90       100
                  ....*....|....*....|
gi 74743052   153 DldppEGSSQEDEDLDSSEG 172
Cdd:pfam04931 703 D----DDDSDSDEDMDDEQM 718
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 66-155 3.66e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 43.38  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    66 NQLEKDQS-RENSINPVQEEEDEGLDSAEgssQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSE----------GS 134
Cdd:pfam04931 621 DVLDARENpEGQQELFEDEDEDEEDDDEE---EDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDelraklaealGE 697

                          90       100
                  ....*....|....*....|.
gi 74743052   135 SQEDEDLDSSEgssqEDEDLD 155
Cdd:pfam04931 698 HGDDADDDDSD----SDEDMD 714
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 99-174 6.72e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 42.23  E-value: 6.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    99 DEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPE----------GSSQEDEDLD 168
Cdd:pfam04931 626 RENPEGQQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDelraklaealGEHGDDADDD 705


                  ....*.
gi 74743052   169 SSEGSS 174
Cdd:pfam04931 706 DSDSDE 711
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 79-171 1.31e-04

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 41.45  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    79 NPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDldSSEGSSQEDEDLDSSEGSSQEDEDLDPPE 158
Cdd:pfam04147 322 IKERPTATELGDEDEDDFIIDDDLVESESDLELDEEEEDEEEEDDEDED--EEEEEDDDDLSDLESEEDEEDDEFEEEKK 399

                          90
                  ....*....|...
gi 74743052   159 GSSQEDEDLDSSE 171
Cdd:pfam04147 400 KKKKKDEEGAKEE 412
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 69-179 1.25e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 38.82  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     69 EKDQSRENSINPVQEEEDEGLDSAEGSSQ-EDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSS--EGSSQEDEDLDSSE 145
Cdd:TIGR00927  658 ENGEESGGEAEQEGETETKGENESEGEIPaERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETeaEGTEDEGEIETGEE 737

                           90       100       110
                   ....*....|....*....|....*....|....
gi 74743052    146 GSSQEDEDLDPPEGSSQEDEDLDSSEGSSQEGGE 179
Cdd:TIGR00927  738 GEEVEDEGEGEAEGKHEVETEGDRKETEHEGETE 771
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 71-171 1.74e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 38.04  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052   71 DQSRENSINPVQEEEDEglDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSS-----------QEDEDLDSSEGSSQEDE 139
Cdd:PRK13108 327 DDVAEAVKAEVAEVTDE--VAAESVVQVADRDGESTPAVEETSEADIEREQPgdlagqapaahQVDAEAASAAPEEPAAL 404

                         90       100       110
                 ....*....|....*....|....*....|..
gi 74743052  140 DLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSE 171
Cdd:PRK13108 405 ASEAHDETEPEVPEKAAPIPDPAKPDELAVAG 436
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 79-165 2.14e-03

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 37.99  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052    79 NPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDldSSEGSSQEDEDLDPPE 158
Cdd:pfam04147 309 DDDDDEEFGLGKGIKERPTATELGDEDEDDFIIDDDLVESESDLELDEEEEDEEEEDDEDED--EEEEEDDDDLSDLESE 386


                  ....*..
gi 74743052   159 GSSQEDE 165
Cdd:pfam04147 387 EDEEDDE 393
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 84-179 2.71e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 37.67  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     84 EEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQ-EDEDLDSSEGSSQEDEdldsSEGSSQEDEDLDPPEGSSQ 162
Cdd:TIGR00927  647 EEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPaERKGEQEGEGEIEAKE----ADHKGETEAEEVEHEGETE 722

                           90
                   ....*....|....*..
gi 74743052    163 EDEDLDSSEGSSQEGGE 179
Cdd:TIGR00927  723 AEGTEDEGEIETGEEGE 739
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 59-169 3.13e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 37.28  E-value: 3.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052   59 KHTKINSNQLEKDQSRENSINPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQED 138
Cdd:PRK05901 104 KKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDDLDDDDIDDDDDDEDDDEDDDDDDVDDEDEEKKEAKELEKLSD 183

                         90       100       110
                 ....*....|....*....|....*....|.
gi 74743052  139 EDLDSSEGSsqEDEDLDPPEGSSQEDEDLDS 169
Cdd:PRK05901 184 DDDFVWDED--DSEALRQARKDAKLTATADP 212
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 80-179 6.10e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 36.51  E-value: 6.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74743052     80 PVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQ-EDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPE 158
Cdd:TIGR00927  656 EGENGEESGGEAEQEGETETKGENESEGEIPaERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETG 735

                           90       100
                   ....*....|....*....|.
gi 74743052    159 GSSQEDEDLDSSEGSSQEGGE 179
Cdd:TIGR00927  736 EEGEEVEDEGEGEAEGKHEVE 756
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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