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Conserved domains on  [gi|94717660|sp|Q56YN3|]
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RecName: Full=NAD(H) kinase 1; Short=AtNADK-1

Protein Classification

diacylglycerol kinase catalytic domain-containing protein; NAD kinase( domain architecture ID 10010937)

diacylglycerol kinase catalytic domain-containing protein is involved in the conversion of diacylglycerol (DAG) to phosphatidic acid (PA), utilizing ATP as a source of the phosphate| ATP-dependent NAD kinase catalyzes the phosphorylation of NAD to NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 23-524 0e+00

Bifunctional NADH kinase/NAD(+) kinase


:

Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 1018.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   23 PNPENGFTHLTSLAQSEKAVQELLlQQTPMQATDDHLVEFSEALRTVAKALRGAAEGKALAQAEAAEWKRRYELERSKNV 102
Cdd:PLN02935   1 SQPDNGFSDSLSLFHSEKAVQELL-QQTPIQDTDDHLVEFSEALRTVAKALRRVAEGKALAQAEAAEWKRKYELERARNQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  103 ELQHKELSNGVCADESNGQRMEHLAKSPRLYAQEISSNGMETICSHEVLQDGGFNS----FNNKLKRKASFKLSWGCKGM 178
Cdd:PLN02935  80 QLEHKELSSGECNEESNDQRLENLANQPMLYNEAINCCGMEGICSHEVLQDGSTDSdnrsVLNKVMRKASFKLSWGCKGD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  179 ANDQHKKEIVSFERGNISTAERSSKQISLTWESDPQTVLIITKPNSTSVRVLSVDMVRWLRTQKGLNIYVEPRVKEELLS 258
Cdd:PLN02935 160 KSDQHKHDIVSFERGNITTAERSSKQISLKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKELLS 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  259 ESSSFNFVQTWEDDKEISLLHTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGP 338
Cdd:PLN02935 240 ESSYFNFVQTWEDEKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGP 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  339 ISITLRHRLQCHIIRDKATHEYEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 418
Cdd:PLN02935 320 ISITLRHRLQCHIIRDAAKNEYETEEPILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  419 GSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTACQVE 498
Cdd:PLN02935 400 GSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVE 479

                        490       500
                 ....*....|....*....|....*.
gi 94717660  499 STNDFLRSIHDGLHWNLRKTQSADGP 524
Cdd:PLN02935 480 STNDFLRSIHDGLHWNLRKTQSFDGP 505
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 23-524 0e+00

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 1018.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   23 PNPENGFTHLTSLAQSEKAVQELLlQQTPMQATDDHLVEFSEALRTVAKALRGAAEGKALAQAEAAEWKRRYELERSKNV 102
Cdd:PLN02935   1 SQPDNGFSDSLSLFHSEKAVQELL-QQTPIQDTDDHLVEFSEALRTVAKALRRVAEGKALAQAEAAEWKRKYELERARNQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  103 ELQHKELSNGVCADESNGQRMEHLAKSPRLYAQEISSNGMETICSHEVLQDGGFNS----FNNKLKRKASFKLSWGCKGM 178
Cdd:PLN02935  80 QLEHKELSSGECNEESNDQRLENLANQPMLYNEAINCCGMEGICSHEVLQDGSTDSdnrsVLNKVMRKASFKLSWGCKGD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  179 ANDQHKKEIVSFERGNISTAERSSKQISLTWESDPQTVLIITKPNSTSVRVLSVDMVRWLRTQKGLNIYVEPRVKEELLS 258
Cdd:PLN02935 160 KSDQHKHDIVSFERGNITTAERSSKQISLKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKELLS 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  259 ESSSFNFVQTWEDDKEISLLHTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGP 338
Cdd:PLN02935 240 ESSYFNFVQTWEDEKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGP 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  339 ISITLRHRLQCHIIRDKATHEYEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 418
Cdd:PLN02935 320 ISITLRHRLQCHIIRDAAKNEYETEEPILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  419 GSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTACQVE 498
Cdd:PLN02935 400 GSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVE 479

                        490       500
                 ....*....|....*....|....*.
gi 94717660  499 STNDFLRSIHDGLHWNLRKTQSADGP 524
Cdd:PLN02935 480 STNDFLRSIHDGLHWNLRKTQSFDGP 505
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
214-516 1.88e-66

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 216.16  E-value: 1.88e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 214 QTVLIITKPNSTSVRVLSVDMVRWLRtQKGLNIYVEPRVKEELLSESSsfnfvqtweddkeislLHTKVDLLITLGGDGT 293
Cdd:COG0061   2 KRIAIVAKPGKPEALEAAEELAELLE-ERGIEVVLDEDTAVPGVPLEE----------------LGEEADLVIVLGGDGT 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 294 VLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKatheyEPEETMLVLNEVT 373
Cdd:COG0061  65 LLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDG-----EVVHEALALNEVV 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 374 IDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVR 453
Cdd:COG0061 140 VLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIE 219

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 94717660 454 VQVPfNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTAcqVESTNDFLRSIHDGLHWNLR 516
Cdd:COG0061 220 IEVL-EDSRPAVLVADGQEVRDLEPGDRVEIRRSPKPVRLL--RLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 369-493 1.78e-32

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 120.48  E-value: 1.78e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   369 LNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPE 448
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 94717660   449 HVTVRVQVPfnSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVST 493
Cdd:pfam20143  81 SSKLRIRVL--SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKF 123
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 23-524 0e+00

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 1018.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   23 PNPENGFTHLTSLAQSEKAVQELLlQQTPMQATDDHLVEFSEALRTVAKALRGAAEGKALAQAEAAEWKRRYELERSKNV 102
Cdd:PLN02935   1 SQPDNGFSDSLSLFHSEKAVQELL-QQTPIQDTDDHLVEFSEALRTVAKALRRVAEGKALAQAEAAEWKRKYELERARNQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  103 ELQHKELSNGVCADESNGQRMEHLAKSPRLYAQEISSNGMETICSHEVLQDGGFNS----FNNKLKRKASFKLSWGCKGM 178
Cdd:PLN02935  80 QLEHKELSSGECNEESNDQRLENLANQPMLYNEAINCCGMEGICSHEVLQDGSTDSdnrsVLNKVMRKASFKLSWGCKGD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  179 ANDQHKKEIVSFERGNISTAERSSKQISLTWESDPQTVLIITKPNSTSVRVLSVDMVRWLRTQKGLNIYVEPRVKEELLS 258
Cdd:PLN02935 160 KSDQHKHDIVSFERGNITTAERSSKQISLKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKELLS 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  259 ESSSFNFVQTWEDDKEISLLHTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGP 338
Cdd:PLN02935 240 ESSYFNFVQTWEDEKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGP 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  339 ISITLRHRLQCHIIRDKATHEYEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 418
Cdd:PLN02935 320 ISITLRHRLQCHIIRDAAKNEYETEEPILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAG 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  419 GSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTACQVE 498
Cdd:PLN02935 400 GSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVE 479

                        490       500
                 ....*....|....*....|....*.
gi 94717660  499 STNDFLRSIHDGLHWNLRKTQSADGP 524
Cdd:PLN02935 480 STNDFLRSIHDGLHWNLRKTQSFDGP 505
PLN02727 PLN02727
NAD kinase
 201-521 8.09e-93

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 304.12  E-value: 8.09e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  201 SSKQISLTWESDPQTVLIITKPNSTSVRVlSVDMVRWLRTQKGLNIYVEPRVkEELLSESSSFNFVQTWEDdKEISLLHT 280
Cdd:PLN02727 666 STQQQMLMWKSTPKTVLLLKKLGQELMEE-AKEVASFLYHQEKMNVLVEPDV-HDIFARIPGFGFVQTFYS-QDTSDLHE 742

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  281 KVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGP-----ISITLRHRLQCHIIRD- 354
Cdd:PLN02727 743 RVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNntldgVYITLRMRLRCEIFRNg 822

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  355 KATheyePEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPI 434
Cdd:PLN02727 823 KAM----PGKVFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPI 898

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  435 CPHSLSFRPLILPEHVTVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTACQVESTNDFLRSIHDGLHWN 514
Cdd:PLN02727 899 CPHSLSFRPVILPDSARLELKIPDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTGDWFRSLIRCLNWN 978


                 ....*..
gi 94717660  515 LRKTQSA 521
Cdd:PLN02727 979 ERLDQKA 985
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
214-516 1.88e-66

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 216.16  E-value: 1.88e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 214 QTVLIITKPNSTSVRVLSVDMVRWLRtQKGLNIYVEPRVKEELLSESSsfnfvqtweddkeislLHTKVDLLITLGGDGT 293
Cdd:COG0061   2 KRIAIVAKPGKPEALEAAEELAELLE-ERGIEVVLDEDTAVPGVPLEE----------------LGEEADLVIVLGGDGT 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 294 VLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKatheyEPEETMLVLNEVT 373
Cdd:COG0061  65 LLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDG-----EVVHEALALNEVV 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 374 IDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVR 453
Cdd:COG0061 140 VLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIE 219

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 94717660 454 VQVPfNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVSTAcqVESTNDFLRSIHDGLHWNLR 516
Cdd:COG0061 220 IEVL-EDSRPAVLVADGQEVRDLEPGDRVEIRRSPKPVRLL--RLKDHSFFERLREKLGWGGD 279
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
160-483 6.32e-41

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 155.27  E-value: 6.32e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  160 NNKL--KRKASFKLSwgckgmANDQHKKEIVSFerGNistaersskqislTWESDPQTVLIITKPNSTSVRVLSVDMVRW 237
Cdd:PRK14076 256 NMKLdiNEKTSVICS------NEILHKKLVGIF--GN-------------KWRIKPTKFGIVSRIDNEEAINLALKIIKY 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  238 LRTqKGLNIYVEPRVKEELLSesssfNFVQTWEDDKEISllhtKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLG 317
Cdd:PRK14076 315 LDS-KGIPYELESFLYNKLKN-----RLNEECNLIDDIE----EISHIISIGGDGTVLRASKLVNGEEIPIICINMGTVG 384

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  318 FMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDkaTHEyepEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCV 397
Cdd:PRK14076 385 FLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILKD--GHQ---NILPSALNEVVITTKNPAKMLHFEVYVNGELVEEV 459

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  398 QGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQVpfnSRSSAWVSFDGKDRKQLE 477
Cdd:PRK14076 460 RADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSANSEIKIKL---LKKSALVVIDGSIEFEAK 536


                 ....*.
gi 94717660  478 AGDALV 483
Cdd:PRK14076 537 KGDEII 542
ppnK PRK02155
NAD kinase;
281-491 2.80e-40

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 147.40  E-value: 2.80e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  281 KVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKathey 360
Cdd:PRK02155  63 RADLAVVLGGDGTMLGIGRQLAPYGVPLIGINHGRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVVRDG----- 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  361 EPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLS 440
Cdd:PRK02155 138 EPIFHALAFNDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVATPTGSTAYALSAGGPILHPQLPGWVLVPIAPHTLS 217

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 94717660  441 FRPLILPEHVTVRVQVPFNSRSSawVSFDGKDRKQLEAGDALVCSMAPWPV 491
Cdd:PRK02155 218 NRPIVLPDDSEVAIQIVGGRDVS--VNFDMQSLTSLELGDRIEVRRSPHTV 266
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 282-471 2.12e-38

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 142.30  E-value: 2.12e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  282 VDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKATheye 361
Cdd:PRK04539  69 CDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKT---- 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  362 pEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSF 441
Cdd:PRK04539 145 -AERALALNDAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTN 223

                        170       180       190
                 ....*....|....*....|....*....|
gi 94717660  442 RPLILPEhvTVRVQVPFNSRSSAWVSFDGK 471
Cdd:PRK04539 224 RPIAIPD--TSEIEILVTQGGDARVHFDGQ 251
ppnK PRK01231
NAD(+) kinase;
215-492 2.97e-37

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 138.94  E-value: 2.97e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  215 TVLIITKPNSTSVRVLSVDMVRWLRTQkGLNIYVEPRVKEEL----LSESSSfnfvqtweddkeiSLLHTKVDLLITLGG 290
Cdd:PRK01231   6 NIGLIGRLGSSSVVETLRRLKDFLLDR-GLEVILDEETAEVLpghgLQTVSR-------------KLLGEVCDLVIVVGG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  291 DGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKatheyEPEETMLVLN 370
Cdd:PRK01231  72 DGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEVRRGG-----EVIGQGDALN 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  371 EVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHV 450
Cdd:PRK01231 147 DVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLVPMFPHTLSSRPIVVDGNS 226

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 94717660  451 TVRVQVPFNSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVS 492
Cdd:PRK01231 227 EIKIVISKDNRTYPRVSCDGQNSVTLAPGDTVTIRKKPQKLR 268
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 278-513 1.04e-36

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 137.36  E-value: 1.04e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  278 LHTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQChiirdkAT 357
Cdd:PRK01911  61 LDGSADMVISIGGDGTFLRTATYVGNSNIPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQL------ES 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  358 HEYEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPH 437
Cdd:PRK01911 135 NPKLFGELNFALNEIAILKRDTSSMITVHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPH 214

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 94717660  438 SLSFRPLILPEHVTVRVQVpfNSRSSAW-VSFDGKDRkQLEAGDALVCSMAPWpvsTACQVESTND-FLRSIHDGLHW 513
Cdd:PRK01911 215 NLNVRPLVIPDDTEITLEV--ESRSDNFlVSLDSRSE-TVDNGTELTIKKADF---TIKLVELNNHsFLKTLRNKLLW 286
ppnK PRK02645
NAD(+) kinase;
281-513 1.07e-35

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 135.04  E-value: 1.07e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  281 KVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGS-LGFMTP----FHSEQYRDCLEAilkGPISITLRHRLQCHIIRDK 355
Cdd:PRK02645  57 LIDLAIVLGGDGTVLAAARHLAPHDIPILSVNVGGhLGFLTHprdlLQDESVWDRLQE---DRYAIERRMMLQARVFEGD 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  356 ATHEYEPEETMLVLNE-----VTIDRGISSyltNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGIL 430
Cdd:PRK02645 134 RSNEEPVSESYYALNDfylkpASEDRSPTC---ILELEIDGEVVDQYQGDGLIVSTPTGSTAYTMAAGGPILHPGIDAII 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  431 FTPICPHSLSFRPLILPEhvtvrvqvpfNSRSSAWVSFDGKDRKQLEAGDALVCSMAP------WPVSTACQV---ESTN 501
Cdd:PRK02645 211 VTPICPMSLSSRPIVIPP----------GSRVVIWPLGDYDLNIKLWKDGVLATSIWPgqrcviQKARHPAKFiilEESY 280

                        250
                 ....*....|..
gi 94717660  502 DFLRSIHDGLHW 513
Cdd:PRK02645 281 SYYRTLREKLHW 292
ppnK PRK03708
NAD(+) kinase;
255-477 2.57e-33

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 127.90  E-value: 2.57e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  255 ELLSESSSFNFVQTWEDDKEISLLHTKVDLLITLGGDGTVLWAASMFKGPVPpIVPFSMGSLGFMTPFHSEQYRDCLEAI 334
Cdd:PRK03708  31 EVVVDSETYEHLPEFSEEDVLPLEEMDVDFIIAIGGDGTILRIEHKTKKDIP-ILGINMGTLGFLTEVEPEETFFALSRL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  335 LKGPISITLRHRLQCHIirdkatheyEPEETMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYS 414
Cdd:PRK03708 110 LEGDYFIDERIKLRVYI---------NGENVPDALNEVVILTGIPGKIIHLKYYVDGELADEVRADGLIISTPTGSTAYA 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 94717660  415 LAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRVQvPFNSRSSAWVSFDGKDRKQLE 477
Cdd:PRK03708 181 MSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVK-LLRTGREIILVIDGQYYEELP 242
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 369-493 1.78e-32

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 120.48  E-value: 1.78e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   369 LNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPE 448
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 94717660   449 HVTVRVQVPfnSRSSAWVSFDGKDRKQLEAGDALVCSMAPWPVST 493
Cdd:pfam20143  81 SSKLRIRVL--SRAEALLVDDGDPELDISPGDRVRVRKSYYKAKF 123
ppnK PRK01185
NAD(+) kinase;
275-487 3.91e-29

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 116.07  E-value: 3.91e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  275 ISLLHTKVDLLITLGGDGTVLWAASMFKGPVPPIvpfSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIird 354
Cdd:PRK01185  46 LDIEEINADVIITIGGDGTILRTLQRAKGPILGI---NMGGLGFLTEIEIDEVGSAIKKLIRGEYFIDERMKLKVYI--- 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  355 kaTHEYEPEETmlvlNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPI 434
Cdd:PRK01185 120 --NGERLEDCT----NEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAGGPILLPNLEGMVISYI 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 94717660  435 CPHSLSFRPLILPEHVTVRVQVPFNSRSsaWVSFDGKDRKQLEAGDALVCSMA 487
Cdd:PRK01185 194 APYSSRPKSVVVPSESTVEIKIAGDQSS--LLILDGQYEYKISKGDTVEISKS 244
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 214-470 1.26e-27

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 112.34  E-value: 1.26e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  214 QTVLIITKPNSTSVRVLSVDMVRWLrTQKGLNIYVEPRVKEEL-LSESSSFNFVQtweddkeislLHTKVDLLITLGGDG 292
Cdd:PRK03378   6 KCIGIVGHPRHPTALTTHEMLYHWL-TSKGYEVIVEQQIAHELqLKNVKTGTLAE----------IGQQADLAIVVGGDG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  293 TVLWAA---SMFKGPVPPIvpfSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIIRDKatheyEPEETMLVL 369
Cdd:PRK03378  75 NMLGAArvlARYDIKVIGI---NRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHG-----QQKRISTAI 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  370 NEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEH 449
Cdd:PRK03378 147 NEVVLHPGKVAHMIEFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSS 226

                        250       260
                 ....*....|....*....|.
gi 94717660  450 VTVRVQVPFNsRSSAWVSFDG 470
Cdd:PRK03378 227 STIRLKFSPN-RSDLEISCDS 246
pnk PRK14077
NAD(+) kinase;
218-473 1.61e-27

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 111.80  E-value: 1.61e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  218 IITKPNSTSVRVLsvdmvrwLRTQKGLNIYveprvKEELLSESSSFNFVQtwEDDKEISLLHTKVDLLITLGGDGTVLWA 297
Cdd:PRK14077  15 LVTRPNVSLDKEI-------LKLQKILSIY-----KVEILLEKESAEILD--LPGYGLDELFKISDFLISLGGDGTLISL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  298 ASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQchiirdkATHEYEPEETM--LVLNEVTID 375
Cdd:PRK14077  81 CRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLS-------VFLEKKQGKILekLAFNDVVIS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  376 RGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEHVTVRvq 455
Cdd:PRK14077 154 KNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTAYNMSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVE-- 231

                        250
                 ....*....|....*...
gi 94717660  456 vpFNSRSSAWVSFDGKDR 473
Cdd:PRK14077 232 --FKTKSDCILCIDGQDR 247
ppnK PRK02231
NAD(+) kinase;
237-446 1.34e-24

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 103.35  E-value: 1.34e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  237 WLRtQKGLNIYVEPRVKEELlseSSSFNFVQTWEddkEISllhTKVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSL 316
Cdd:PRK02231   8 WLK-ERGYQVLVEKEIAEQL---NLPENHLASLE---EIG---QRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  317 GFMT---PFHS-EQYRDCLEailKGPISITLRHRLQCHIIRDKatheyEPEETMLVLNEVTIDRGISSYLTNLECYCDNS 392
Cdd:PRK02231  78 GFLTdidPKNAyEQLEACLE---RGEFFVEERFLLEAKIERNG-----KIIATSNALNEVVIHPAKIAHMIDFHVYIDDK 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 94717660  393 FVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLIL 446
Cdd:PRK02231 150 FAFSQRSDGLIISTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVI 203
ppnK PRK02649
NAD(+) kinase;
279-452 1.50e-24

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 103.91  E-value: 1.50e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  279 HTKVDLL------------ITLGGDGTVLWAASMFkGPVP-PIVPFSMGSLGFMTPFHSEQYRDCLEAILKGPISITLRH 345
Cdd:PRK02649  54 HTGIDQLvppgfdssmkfaIVLGGDGTVLSAARQL-APCGiPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERT 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  346 RLQCHIIRDKaTHEYEpeetMLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQ 425
Cdd:PRK02649 133 MLTVSVMRGD-QLRWE----ALSLNEMVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPD 207

                        170       180
                 ....*....|....*....|....*....
gi 94717660  426 VPGILFTPICPHSLSFRPLILP--EHVTV 452
Cdd:PRK02649 208 VPVLQLTPICPHSLASRALVFSdsEPVTV 236
pnk PRK14075
NAD(+) kinase;
252-455 5.88e-23

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 98.26  E-value: 5.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  252 VKEELLSESSSFNFVQTWEDDKeisllhTKVDLLITLGGDGTVLWAAsmfKGPVPPIVPFSMGSLGFMTPFHSEQYRDCL 331
Cdd:PRK14075  18 LKEKISKEHEVVEFCEASASGK------VTADLIIVVGGDGTVLKAA---KKVGTPLVGFKAGRLGFLSSYTLEEIDRFL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  332 EAILKGPISITLRHRLQchIIRDKATHeyepeetmLVLNEVTIDRGISSYLTNLECYCDNSFVTCVQGDGLILSTTSGST 411
Cdd:PRK14075  89 EDLKNWNFREEKRWFLK--IESELGNH--------LALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGST 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 94717660  412 AYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILP--EHVTVRVQ 455
Cdd:PRK14075 159 AYSLSLGGPIILPNCEVFEITPIAPQFLATRSIVIPsnEKVTVESQ 204
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 282-477 3.28e-19

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 88.44  E-value: 3.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  282 VDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKG--------PISITLRHRLQcHIIR 353
Cdd:PRK03372  73 CELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLAEAEAEDLDEAVERVVDRdyrveermTLDVTVRVGGE-IVWR 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  354 DKAtheyepeetmlvLNEVTIDRGisSYLTNLECycdnsfVTCVQG--------DGLILSTTSGSTAYSLAAGGSMVHPQ 425
Cdd:PRK03372 152 GWA------------LNEASLEKA--DREGMLEV------VLEVDGrpvssfgcDGVLVSTPTGSTAYAFSAGGPVVWPD 211

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 94717660  426 VPGILFTPICPHSLSFRPLILPEHVTVRVQVpFNSRSSAWVSFDGkdRKQLE 477
Cdd:PRK03372 212 LEALLVVPLNAHALFARPLVVSPTSTVAVEI-LADTSDAVLWCDG--RRSVD 260
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 216-336 5.19e-18

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 80.10  E-value: 5.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660   216 VLIITKPNSTSVRVLSVDMVRWLRTQKGLNIYVEPRVKEELLSESSS-FNFVQTWEDDKEISLLHT------KVDLLITL 288
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDRLGITVTVEEKMGESLAFAAGDrPEVIGCLKKVVDDTRRATrafadaGVDLIIVL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 94717660   289 GGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILK 336
Cdd:pfam01513  81 GGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 251-472 2.05e-17

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 82.17  E-value: 2.05e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  251 RVKEELLSESSSFNFVQtweDDKEisllhtkVDLLITLGGDGTVLWAASMFKGPVPPI--VPFSMGSLGFMTPFHSEQYR 328
Cdd:PRK04885  15 RVASKLKKYLKDFGFIL---DEKN-------PDIVISVGGDGTLLSAFHRYENQLDKVrfVGVHTGHLGFYTDWRPFEVD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  329 DCLEAILKGP---ISITLrhrlqchiIRDKATHEYEPEETMLVLNEVTIDRGISSYLTNLECYcDNSFVTcVQGDGLILS 405
Cdd:PRK04885  85 KLVIALAKDPgqvVSYPL--------LEVKITYEDGEKEKYLALNEATIKRIEGTLVADVYIN-GVLFER-FRGDGLCVS 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 94717660  406 TTSGSTAYSLAAGGSMVHPQVPGILFTPICphSLS---FR----PLILPEHVTVRVqVPFNSrSSAWVSFDGKD 472
Cdd:PRK04885 155 TPTGSTAYNKSLGGAVLHPSIEALQLTEIA--SINnrvFRtlgsPLILPKHHTITL-KPVND-DDYQITVDHLT 224
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 281-456 1.99e-11

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 64.07  E-value: 1.99e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  281 KVDLLITLGGDGTVLWAA-SMFKGPVPpIVPFSMGSLGF-MTPFHSEQYRDCLEAilkgpisitlRHRLQCHIIRDKATH 358
Cdd:PRK04761  25 EADVIVALGGDGFMLQTLhRYMNSGKP-VYGMNRGSVGFlMNEYSEDDLLERIAA----------AEPTVLHPLRMTATD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  359 EYEPEETMLVLNEVTIDRgiSSYLT-NLECYCDN-----SFVtcvqGDGLILSTTSGSTAYSLAAGGsmvhPQVP---GI 429
Cdd:PRK04761  94 VSGEVHEALAINEVSLFR--QTRQAaKLRISIDGkvrmeELV----CDGVLVATPAGSTAYNLSAHG----PILPlgsNL 163

                        170       180       190
                 ....*....|....*....|....*....|...
gi 94717660  430 L-FTPICPhslsFRP-----LILPEHVTVRVQV 456
Cdd:PRK04761 164 LaLTPISP----FRPrrwrgALLPNSATVRFDV 192
ppnK PRK00561
NAD(+) kinase;
283-470 1.14e-09

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 59.12  E-value: 1.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  283 DLLITLGGDGTVLWAASMFKGPVPPIVPFSMGSLGFMTPFHSEQYRDCLEAILKgpisitlrhrlQCHIIRDKATHEYEP 362
Cdd:PRK00561  35 DYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNETDLDQNFANKLD-----------QLKFTQIDLLEVQID 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  363 EETMLVLNEVTIDRGiSSYLTNLecYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICP--HSlS 440
Cdd:PRK00561 104 DQIHLVLNELAVYTN-TAYPINI--FIDNEFWEKYRGSGLLIGPRTGSTALAKSAKGAVIFPRIDVIQIIELNPllHP-N 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 94717660  441 F----RPLILPEHVTVRVQVPFNSRSSAWVSF--DG 470
Cdd:PRK00561 180 QttiqSPIILPIDTKVEFEIKKAFDHDQFPRFyaDG 215
ppnK PRK03501
NAD kinase;
245-429 3.55e-09

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 57.68  E-value: 3.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  245 NIYVEPRVKEEL---------LSESSSFNFVqtweDDkeisllHTKVDLLITLGGDGTVLWAA--SMFKGPVPPIVPFSM 313
Cdd:PRK03501   4 NLFFFYKRDKELvekvkplkkIAEEYGFTVV----DH------PKNANIIVSIGGDGTFLQAVrkTGFREDCLYAGISTK 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660  314 GSLGFMTPFHSEQYRDCLEAILKGPISITLRHRLQCHIirDKATHeyepeetMLVLNEVTIDRGISSYLTnLECYCDNSF 393
Cdd:PRK03501  74 DQLGFYCDFHIDDLDKMIQAITKEEIEVRKYPTIEVTV--DGSTS-------FYCLNEFSIRSSIIKTFV-IDVYIDDLH 143

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 94717660  394 VTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGI 429
Cdd:PRK03501 144 FETFRGDGMVVSTPTGSTAYNKSVRGAVVDPLIPCF 179
DAGK_cat pfam00781
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts ...
 240-310 7.38e-04

Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.


Pssm-ID: 425868 [Multi-domain]  Cd Length: 125  Bit Score: 39.49  E-value: 7.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94717660   240 TQKGLNIYvePRVKEELLSESSSFNFVQTWEDDKEISLL----HTKVDLLITLGGDGTVLWAAS-MFKGPVPP---IVP 310
Cdd:pfam00781  12 GGKGKKLL--RKVRPLLNKAGVEVELVLTEGPGDALELAreaaEDGYDRIVVAGGDGTVNEVLNgLAGLATRPplgIIP 88
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 52-118 3.74e-03

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 39.24  E-value: 3.74e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 94717660    52 MQATDDHLVEFSEALRTVAKALRGAAEGKALAQAEAAEWKRR-----YELERSKNV--ELQHKELSNGVCADES 118
Cdd:pfam00261   3 MQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALNRRiqlleEELERTEERlaEALEKLEEAEKAADES 76
LCB5 COG1597
Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, ...
 242-339 5.11e-03

Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, General function prediction only];


Pssm-ID: 441205 [Multi-domain]  Cd Length: 295  Bit Score: 39.07  E-value: 5.11e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94717660 242 KGLNIYVEPRVKEELLSESSSFNFVQTWEDDKEISLLHT----KVDLLITLGGDGTVLWAASMFKGPVPPIVPFSMGS-- 315
Cdd:COG1597  15 RGRAARLLERLVAALRAAGLEVEVLETESPGDATELAREaaaeGADLVVAAGGDGTVNEVANGLAGTGPPLGILPLGTgn 94

                        90       100
                ....*....|....*....|....*....
gi 94717660 316 -----LGFmtPFHSEQyrdCLEAILKGPI 339
Cdd:COG1597  95 dfaraLGI--PLDPEA---ALEALLTGRT 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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