NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|81882380|sp|Q569C2|]
View 

RecName: Full=LRP2-binding protein

Protein Classification

SEL1-like repeat protein( domain architecture ID 11434924)

SEL1-like repeat family protein may function as an adaptor protein for the assembly of macromolecular complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  16870393
SCOP:  3001345

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
39-254 5.65e-33

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 122.73  E-value: 5.65e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  39 ANLVDTALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTVADAEKGVGYMKK 118
Cdd:COG0790  13 AAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEK 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 119 ILDSSCPQtmhlkfaAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKAsvkaQSILGLFYSMKE--PKDLEKAFFW 196
Cdd:COG0790  93 AAEQGDAE-------AQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADA----QYNLGLLYLNGEgvPKDPAKAAEW 161

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 81882380 197 HSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYK 254
Cdd:COG0790 162 YRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLN 219
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 296-330 1.93e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


:

Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 1.93e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 81882380    296 AMASFYYARCLQLGLGITKDEASAKHYYSKACRLN 330
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
39-254 5.65e-33

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 122.73  E-value: 5.65e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  39 ANLVDTALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTVADAEKGVGYMKK 118
Cdd:COG0790  13 AAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEK 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 119 ILDSSCPQtmhlkfaAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKAsvkaQSILGLFYSMKE--PKDLEKAFFW 196
Cdd:COG0790  93 AAEQGDAE-------AQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADA----QYNLGLLYLNGEgvPKDPAKAAEW 161

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 81882380 197 HSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYK 254
Cdd:COG0790 162 YRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLN 219
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 207-241 3.40e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 40.23  E-value: 3.40e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 81882380    207 ESQGALGLMYLYGQGIRQDTDAALHCLREAAERGN 241
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 207-240 1.09e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.04  E-value: 1.09e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 81882380   207 ESQGALGLMYLYGQGIRQDTDAALHCLREAAERG 240
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 296-330 1.93e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 1.93e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 81882380    296 AMASFYYARCLQLGLGITKDEASAKHYYSKACRLN 330
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 296-330 3.65e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.80  E-value: 3.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 81882380   296 AMASFYYARCLQLGLGITKDEASAKHYYSKACRLN 330
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
39-254 5.65e-33

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 122.73  E-value: 5.65e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  39 ANLVDTALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTVADAEKGVGYMKK 118
Cdd:COG0790  13 AAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEK 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 119 ILDSSCPQtmhlkfaAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKAsvkaQSILGLFYSMKE--PKDLEKAFFW 196
Cdd:COG0790  93 AAEQGDAE-------AQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADA----QYNLGLLYLNGEgvPKDPAKAAEW 161

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 81882380 197 HSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYK 254
Cdd:COG0790 162 YRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLN 219
TPR COG0790
TPR repeat [General function prediction only];
14-239 1.34e-28

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 110.79  E-value: 1.34e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  14 SLSQYAAKQQTFFQWKKEKPDYYRHANLVDTALQFLKERIRKGDAMAYFLRGQLYfEEGW-----YEEALAQFEEIQEKD 88
Cdd:COG0790  19 AAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMY-AEGRgvpkdYEKALEWFEKAAEQG 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  89 H-QAIYQLGVMYYDGLGTVADAEKGVGYMKKILDSSCPQtmhlkfaAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGN 167
Cdd:COG0790  98 DaEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDAD-------AQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGD 170

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 81882380 168 PKAsvkaQSILGLFYSMKE--PKDLEKAFFWHSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAER 239
Cdd:COG0790 171 ADA----QYNLGVLYENGRgvPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
133-329 6.64e-28

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 109.25  E-value: 6.64e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 133 AAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKAsvkaQSILGLFYSMKE--PKDLEKAFFWHSEACGNGNLESQG 210
Cdd:COG0790  64 EAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEA----QYNLGLMYEEGLgvPQDYAKALEWYEKAAEQGDADAQY 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 211 ALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYKMKF----FTKCVSFSKRIADydevhdipmiahvtdc 286
Cdd:COG0790 140 NLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGvpkdPAKALEWYRKAAE---------------- 203

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 81882380 287 lpefisKGMAMASFYYARCLQLGLGITKDEASAKHYYSKACRL 329
Cdd:COG0790 204 ------QGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
155-330 1.37e-10

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 60.71  E-value: 1.37e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 155 AERLWLYAADNGNPKASVKAQSILGLFYSMKEPKDLEKAFFWHSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLR 234
Cdd:COG0790  12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 235 EAAERGNVYAQGILVEYYYK----MKFFTKCVSFSKRIADydevhdipmiahvtdclpefisKGMAMASFYYARCLQLGL 310
Cdd:COG0790  92 KAAEQGDAEAQYNLGLMYEEglgvPQDYAKALEWYEKAAE----------------------QGDADAQYNLGLLYLNGE 149

                       170       180
                ....*....|....*....|
gi 81882380 311 GITKDEASAKHYYSKACRLN 330
Cdd:COG0790 150 GVPKDPAKAAEWYRKAAEQG 169
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 58-337 3.62e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.80  E-value: 3.62e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  58 AMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAI---YQLGVMYYDgLGtvaDAEKGVGYMKKILDSScPQtmhlKFAA 134
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVeahLALGNLYRR-RG---EYDRAIRIHQKLLERD-PD----RAEA 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 135 AYNLGRAYFEGKgvkrSDEEAERLWLYAADNgNPKAsVKAQSILGLFYSMKepKDLEKAFFWHSEACGNGNLESQGALGL 214
Cdd:COG2956  79 LLELAQDYLKAG----LLDRAEELLEKLLEL-DPDD-AEALRLLAEIYEQE--GDWEKAIEVLERLLKLGPENAHAYCEL 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 215 MYLYGQgiRQDTDAALHCLREA--AERGNVYAQGILVEYYYKMKFFTKCVSFSKRIADYDevhdipmiahvtdclPEFIS 292
Cdd:COG2956 151 AELYLE--QGDYDEAIEALEKAlkLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD---------------PDYLP 213

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 81882380 293 KGMAMASFYYARclqlglgitKDEASAKHYYSKACRLNPTLADEL 337
Cdd:COG2956 214 ALPRLAELYEKL---------GDPEEALELLRKALELDPSDDLLL 249
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 36-239 9.93e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.65  E-value: 9.93e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  36 YRHANLVDTALQFLKERIRKGD--AMAYFLRGQLYFEEGWYEEALAQFEEIQEKDH---QAIYQLGVMYYDglgtVADAE 110
Cdd:COG2956  52 YRRRGEYDRAIRIHQKLLERDPdrAEALLELAQDYLKAGLLDRAEELLEKLLELDPddaEALRLLAEIYEQ----EGDWE 127

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 111 KGVGYMKKILDSScPQTMHlkfaAAYNLGRAYFEgkgvKRSDEEAERLWLYAADNgNPKaSVKAQSILGLFYSMKepKDL 190
Cdd:COG2956 128 KAIEVLERLLKLG-PENAH----AYCELAELYLE----QGDYDEAIEALEKALKL-DPD-CARALLLLAELYLEQ--GDY 194

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 81882380 191 EKAFFWHSEACGNGNLESQGALGLMYLYGQgiRQDTDAALHCLREAAER 239
Cdd:COG2956 195 EEAIAALERALEQDPDYLPALPRLAELYEK--LGDPEEALELLRKALEL 241
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 207-241 3.40e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 40.23  E-value: 3.40e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 81882380    207 ESQGALGLMYLYGQGIRQDTDAALHCLREAAERGN 241
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 15-111 9.53e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 9.53e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  15 LSQYAAKQQTFFQWKKEKPDYYR-HANL---------VDTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFE 82
Cdd:COG3914  91 LGRYEEALALYRRALALNPDNAEaLFNLgnlllalgrLEEALAALRRalALNPDFAEAYLNLGEALRRLGRLEEAIAALR 170

                        90       100       110
                ....*....|....*....|....*....|..
gi 81882380  83 ---EIQEKDHQAIYQLGVMYYDgLGTVADAEK 111
Cdd:COG3914 171 ralELDPDNAEALNNLGNALQD-LGRLEEAIA 201
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 207-240 1.09e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.04  E-value: 1.09e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 81882380   207 ESQGALGLMYLYGQGIRQDTDAALHCLREAAERG 240
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 134-167 1.59e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 38.31  E-value: 1.59e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 81882380    134 AAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGN 167
Cdd:smart00671   3 AQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 43-255 1.86e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 1.86e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  43 DTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQ---AIYQLGVMYYDgLGTVADAEKgvgYMK 117
Cdd:COG2956  25 DKAIDLLEEalELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDraeALLELAQDYLK-AGLLDRAEE---LLE 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 118 KILDSScpqtmHLKFAAAYNLGRAYFEGKGVKRSDEEAERLwlyAADNGNpkaSVKAQSILGLFYSMKepKDLEKAFFWH 197
Cdd:COG2956 101 KLLELD-----PDDAEALRLLAEIYEQEGDWEKAIEVLERL---LKLGPE---NAHAYCELAELYLEQ--GDYDEAIEAL 167

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 81882380 198 SEACG--NGNLESQGALGLMYLygqgIRQDTDAALHCLREAAERGNVYAQGI--LVEYYYKM 255
Cdd:COG2956 168 EKALKldPDCARALLLLAELYL----EQGDYEEAIAALERALEQDPDYLPALprLAELYEKL 225
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 133-166 3.03e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 37.50  E-value: 3.03e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 81882380   133 AAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNG 166
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
52-254 3.72e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 3.72e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  52 RIRKGDAMAYFLRGQLYFEEGWYEEALAQFE---EIQEKDHQAIYQLGVMYYDgLGTVADAEKgvgYMKKILDsscpqtM 128
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEkalELDPDDAEALYNLGLAYLR-LGRYEEALA---DYEQALE------L 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 129 HLKFAAAY-NLGRAYFEgkgvKRSDEEAERLWLYAADNgNPKaSVKAQSILGLFYSMKepKDLEKAFFWHSEAC--GNGN 205
Cdd:COG0457  72 DPDDAEALnNLGLALQA----LGRYEEALEDYDKALEL-DPD-DAEALYNLGLALLEL--GRYDEAIEAYERALelDPDD 143

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 81882380 206 LESQGALGLMYLYgqgiRQDTDAALHCLREAAERGNVYAQGILVEYYYK 254
Cdd:COG0457 144 ADALYNLGIALEK----LGRYEEALELLEKLEAAALAALLAAALGEAAL 188
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 34-160 6.11e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 6.11e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  34 DYYRHANLVDTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEI--QEKDHQAIYQLGVMYYDGLGTVADA 109
Cdd:COG2956 152 ELYLEQGDYDEAIEALEKalKLDPDCARALLLLAELYLEQGDYEEAIAALERAleQDPDYLPALPRLAELYEKLGDPEEA 231

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 81882380 110 EKgvgYMKKILDSscpqtmHLKFAAAYNLGRAYFEGKGvkrsDEEAERLWL 160
Cdd:COG2956 232 LE---LLRKALEL------DPSDDLLLALADLLERKEG----LEAALALLE 269
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 45-175 9.62e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 9.62e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  45 ALQFLKERIRK--GDAMAYFLRGQLYFEEGWYEEALAQFE---EIQEKDHQAIYQLGVMYYDGlgtvADAEKGVGYMKKI 119
Cdd:COG4235   2 AIARLRQALAAnpNDAEGWLLLGRAYLRLGRYDEALAAYEkalRLDPDNADALLDLAEALLAA----GDTEEAEELLERA 77

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 81882380 120 L--DSSCPQtmhlkfaAAYNLGRAYFEgkgvKRSDEEAERLW---LYAADNGNPKASVKAQ 175
Cdd:COG4235  78 LalDPDNPE-------ALYLLGLAAFQ----QGDYAEAIAAWqklLALLPADAPARLLEAS 127
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 296-330 1.93e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 1.93e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 81882380    296 AMASFYYARCLQLGLGITKDEASAKHYYSKACRLN 330
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-165 3.10e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 3.10e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  43 DTALQFLKERIRK--GDAMAYFLRGQLYFEEGWYEEALAQFEE---IQEKDHQAIYQLGVMYYDgLGTVADAEKgvgYMK 117
Cdd:COG4783  21 DEAEALLEKALELdpDNPEAFALLGEILLQLGDLDEAIVLLHEaleLDPDEPEARLNLGLALLK-AGDYDEALA---LLE 96

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 81882380 118 KILDSScPQTMhlkfAAAYNLGRAYFEGKGVKRSDEEAERLWLYAADN 165
Cdd:COG4783  97 KALKLD-PEHP----EAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 296-330 3.65e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.80  E-value: 3.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 81882380   296 AMASFYYARCLQLGLGITKDEASAKHYYSKACRLN 330
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 34-101 4.17e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.91  E-value: 4.17e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 81882380  34 DYYRHANLVDTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDH---QAIYQLGVMYYD 101
Cdd:COG4235  25 RAYLRLGRYDEALAAYEKalRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPdnpEALYLLGLAAFQ 97
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 36-111 7.52e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 36.32  E-value: 7.52e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  36 YRHANLVDTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFE---EIQEKDHQAIYQLGVMYYDgLGTVADAE 110
Cdd:COG4783  48 LLQLGDLDEAIVLLHEalELDPDEPEARLNLGLALLKAGDYDEALALLEkalKLDPEHPEAYLRLARAYRA-LGRPDEAI 126


                .
gi 81882380 111 K 111
Cdd:COG4783 127 A 127
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-100 7.53e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 37.68  E-value: 7.53e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  36 YRHANLVDTALQFLKE--RIRKGDAMAYFLRGQLYFEEGWYEEALAQFE---EIQEKDHQAIYQLGVMYY 100
Cdd:COG0457  86 LQALGRYEEALEDYDKalELDPDDAEALYNLGLALLELGRYDEAIEAYEralELDPDDADALYNLGIALE 155
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 58-193 8.63e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 38.05  E-value: 8.63e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380  58 AMAYFLRGQLYFEEGWYEEALAQFE---EIQEKDHQAIYQLGVMYYDgLGTVADAEKgvgYMKKILDsscpqtMHLKFAA 134
Cdd:COG3914  78 AALLELAALLLQALGRYEEALALYRralALNPDNAEALFNLGNLLLA-LGRLEEALA---ALRRALA------LNPDFAE 147

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 81882380 135 AY-NLGRAYFEgkgvKRSDEEAERLWLYAADNgNPKaSVKAQSILGLFYsmKEPKDLEKA 193
Cdd:COG3914 148 AYlNLGEALRR----LGRLEEAIAALRRALEL-DPD-NAEALNNLGNAL--QDLGRLEEA 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH