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Conserved domains on  [gi|109940305|sp|Q3UJZ3|]
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RecName: Full=Armadillo repeat-containing protein 7

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 10453181)

armadillo/beta-catenin-like repeat-containing protein similar to plakophilin and armadillo repeat-containing protein

CATH:  1.25.10.10
Gene Ontology:  GO:0098609|GO:0005515
PubMed:  12946625|9770300|9298899|20688255
SCOP:  3000116

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 87-127 5.22e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.97  E-value: 5.22e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 109940305   87 DKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSS 127
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
27-126 7.65e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 36.41  E-value: 7.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109940305  27 TESQDAKEQVLANLANFAYD-PGNYQYLRQLQVLDLFLDSLSEE--NETLIKFAIGGLCNLCADK---ANKEHVLQAggL 100
Cdd:COG5064  168 STEDDVREQAVWALGNIAGDsEGCRDYVLQCGALEPLLGLLLSSaiHISMLRNATWTLSNLCRGKnppPDWSNISQA--L 245

                         90       100
                 ....*....|....*....|....*.
gi 109940305 101 PLIIGCLSSPDEETVLSAVTTLMYLS 126
Cdd:COG5064  246 PILAKLIYSRDPEVLVDACWAISYLS 271
 
Name Accession Description Interval E-value
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 87-127 5.22e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.97  E-value: 5.22e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 109940305   87 DKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSS 127
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 87-127 8.27e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 8.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 109940305    87 DKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSS 127
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
27-126 7.65e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 36.41  E-value: 7.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109940305  27 TESQDAKEQVLANLANFAYD-PGNYQYLRQLQVLDLFLDSLSEE--NETLIKFAIGGLCNLCADK---ANKEHVLQAggL 100
Cdd:COG5064  168 STEDDVREQAVWALGNIAGDsEGCRDYVLQCGALEPLLGLLLSSaiHISMLRNATWTLSNLCRGKnppPDWSNISQA--L 245

                         90       100
                 ....*....|....*....|....*.
gi 109940305 101 PLIIGCLSSPDEETVLSAVTTLMYLS 126
Cdd:COG5064  246 PILAKLIYSRDPEVLVDACWAISYLS 271
 
Name Accession Description Interval E-value
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 87-127 5.22e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.97  E-value: 5.22e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 109940305   87 DKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSS 127
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 87-127 8.27e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 8.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 109940305    87 DKANKEHVLQAGGLPLIIGCLSSPDEETVLSAVTTLMYLSS 127
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
27-126 7.65e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 36.41  E-value: 7.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109940305  27 TESQDAKEQVLANLANFAYD-PGNYQYLRQLQVLDLFLDSLSEE--NETLIKFAIGGLCNLCADK---ANKEHVLQAggL 100
Cdd:COG5064  168 STEDDVREQAVWALGNIAGDsEGCRDYVLQCGALEPLLGLLLSSaiHISMLRNATWTLSNLCRGKnppPDWSNISQA--L 245

                         90       100
                 ....*....|....*....|....*.
gi 109940305 101 PLIIGCLSSPDEETVLSAVTTLMYLS 126
Cdd:COG5064  246 PILAKLIYSRDPEVLVDACWAISYLS 271
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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