NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|122138185|sp|Q2YDH0|]
View 

RecName: Full=Sialomucin core protein 24; Short=MUC-24; AltName: Full=Endolyn; AltName: CD_antigen=CD164; Flags: Precursor

Protein Classification

MGC-24 domain-containing protein( domain architecture ID 12062574)

MGC-24 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MGC-24 pfam05283
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 65-198 1.84e-52

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


:

Pssm-ID: 461610  Cd Length: 140  Bit Score: 165.04  E-value: 1.84e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185   65 ICGSRNSCVSCVDG---NATCFWIECKG--KSYCSDNSTAGDCKVVNTTGFCSVPTTTP-TPTNSTAKTTTLPSTTTTST 138
Cdd:pfam05283   1 TCGSRNSCESCVNGsndNSTCFWMECKPeeKSYCSANSTVSDCSVVNRTEFCSAPHTTTpKPTNSTAKTTTLPSSSTTST 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185  139 TATTSGTTNTTLSPTIQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL 198
Cdd:pfam05283  81 TVATTGTTNTTLTPTSQPTHKSTFDAASFIGGIVLVLGLQAVIFFLYKFCKSKDRNYHTL 140
 
Name Accession Description Interval E-value
MGC-24 pfam05283
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 65-198 1.84e-52

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


Pssm-ID: 461610  Cd Length: 140  Bit Score: 165.04  E-value: 1.84e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185   65 ICGSRNSCVSCVDG---NATCFWIECKG--KSYCSDNSTAGDCKVVNTTGFCSVPTTTP-TPTNSTAKTTTLPSTTTTST 138
Cdd:pfam05283   1 TCGSRNSCESCVNGsndNSTCFWMECKPeeKSYCSANSTVSDCSVVNRTEFCSAPHTTTpKPTNSTAKTTTLPSSSTTST 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185  139 TATTSGTTNTTLSPTIQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL 198
Cdd:pfam05283  81 TVATTGTTNTTLTPTSQPTHKSTFDAASFIGGIVLVLGLQAVIFFLYKFCKSKDRNYHTL 140
 
Name Accession Description Interval E-value
MGC-24 pfam05283
Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several ...
 65-198 1.84e-52

Multi-glycosylated core protein 24 (MGC-24), sialomucin; This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.


Pssm-ID: 461610  Cd Length: 140  Bit Score: 165.04  E-value: 1.84e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185   65 ICGSRNSCVSCVDG---NATCFWIECKG--KSYCSDNSTAGDCKVVNTTGFCSVPTTTP-TPTNSTAKTTTLPSTTTTST 138
Cdd:pfam05283   1 TCGSRNSCESCVNGsndNSTCFWMECKPeeKSYCSANSTVSDCSVVNRTEFCSAPHTTTpKPTNSTAKTTTLPSSSTTST 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 122138185  139 TATTSGTTNTTLSPTIQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL 198
Cdd:pfam05283  81 TVATTGTTNTTLTPTSQPTHKSTFDAASFIGGIVLVLGLQAVIFFLYKFCKSKDRNYHTL 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH