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Conserved domains on  [gi|7387810|sp|Q12657|]
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RecName: Full=Adenylyl-sulfate kinase; AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; AltName: Full=Adenosine-5'-phosphosulfate kinase; Short=APS kinase

Protein Classification

adenylyl-sulfate kinase( domain architecture ID 10785573)

adenylylsulfate kinase catalyzes the ATP-dependent phosphorylation of adenosine 5'-phosphosulfate (APS) to 3'-phosphoadenosine-5'-phosphosulfate (PAPS)

CATH:  3.40.50.300
EC:  2.7.1.25
Gene Ontology:  GO:0004020|GO:0005524|GO:0000103
SCOP:  4003930

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 10-207 1.16e-109

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


:

Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 312.02  E-value: 1.16e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   10 SALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAE 89
Cdd:COG0529   1 SAVTREERAALKGQKGFVVWFTGLSGSGKSTLANALERRL-FERGRHVYLLDGDNVRHGLNKDLGFSKEDRDENIRRIGE 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   90 VAKLFADSNSIAITSFISPYRKDRDTARQLHEvatPGEetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGIS 169
Cdd:COG0529  80 VAKLLADAGLIVLVAFISPYRADREEARELIG---EGE-----FIEVYVDTPLEVCEARDPKGLYAKARAGEIKNFTGID 151

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 7387810  170 APYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLP 207
Cdd:COG0529 152 DPYEAPENPELVLDTDKESVEESVEKILAYLEERGYIS 189
 
Name Accession Description Interval E-value
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 10-207 1.16e-109

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 312.02  E-value: 1.16e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   10 SALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAE 89
Cdd:COG0529   1 SAVTREERAALKGQKGFVVWFTGLSGSGKSTLANALERRL-FERGRHVYLLDGDNVRHGLNKDLGFSKEDRDENIRRIGE 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   90 VAKLFADSNSIAITSFISPYRKDRDTARQLHEvatPGEetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGIS 169
Cdd:COG0529  80 VAKLLADAGLIVLVAFISPYRADREEARELIG---EGE-----FIEVYVDTPLEVCEARDPKGLYAKARAGEIKNFTGID 151

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 7387810  170 APYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLP 207
Cdd:COG0529 152 DPYEAPENPELVLDTDKESVEESVEKILAYLEERGYIS 189
PRK03846 PRK03846
adenylylsulfate kinase; Provisional
 2-208 2.15e-97

adenylylsulfate kinase; Provisional


Pssm-ID: 179661  Cd Length: 198  Bit Score: 281.44  E-value: 2.15e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     2 STNITFHASALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLVrDRRVHAYRLDGDNIRFGLNKDLGFSEADRN 81
Cdd:PRK03846   1 DENIVWHQHPVTKAQREQLHGHKGVVLWFTGLSGSGKSTVAGALEEALH-ELGVSTYLLDGDNVRHGLCSDLGFSDADRK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    82 ENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEvatPGEetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGV 161
Cdd:PRK03846  80 ENIRRVGEVAKLMVDAGLVVLTAFISPHRAERQMVRERLG---EGE-----FIEVFVDTPLAICEARDPKGLYKKARAGE 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 7387810   162 IKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLPA 208
Cdd:PRK03846 152 IRNFTGIDSVYEAPESPEIHLDTGEQLVTNLVEQLLDYLRQRDIIRS 198
APS_kinase pfam01583
Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3 ...
 24-186 5.52e-97

Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3'-phosphoadenylylsulfate. This domain contains an ATP binding P-loop motif.


Pssm-ID: 396247 [Multi-domain]  Cd Length: 154  Bit Score: 278.82  E-value: 5.52e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     24 RGLTIWLTGLSASGKSTLAVELEHQLVrDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAIT 103
Cdd:pfam01583   1 RGCTIWLTGLSGAGKSTIANALERKLF-EQGRSVYVLDGDNVRHGLNKDLGFSEEDRTENIRRIGEVAKLFADAGLIVIT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    104 SFISPYRKDRDTARQLHEVAtpgeetglPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVK 183
Cdd:pfam01583  80 AFISPYREDREQARELHEEG--------KFIEVFVDTPLEVCEQRDPKGLYKKARAGEIKGFTGIDSPYEAPENPELVLD 151


                  ...
gi 7387810    184 NYE 186
Cdd:pfam01583 152 TDK 154
APSK cd02027
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5 ...
 27-183 2.35e-92

Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.


Pssm-ID: 238985 [Multi-domain]  Cd Length: 149  Bit Score: 266.65  E-value: 2.35e-92
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   27 TIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAITSFI 106
Cdd:cd02027   1 VIWLTGLSGSGKSTIARALEEKL-FQRGRPVYVLDGDNVRHGLNKDLGFSREDREENIRRIAEVAKLLADAGLIVIAAFI 79

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7387810  107 SPYRKDRDTARQLHEvatpgeetGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVK 183
Cdd:cd02027  80 SPYREDREAARKIIG--------GGDFLEVFVDTPLEVCEQRDPKGLYKKARAGEIKGFTGIDDPYEAPENPDLVLD 148
apsK TIGR00455
adenylyl-sulfate kinase; This protein, adenylylsulfate kinase, is often found as a fusion ...
 10-200 1.35e-88

adenylyl-sulfate kinase; This protein, adenylylsulfate kinase, is often found as a fusion protein with sulfate adenylyltransferase. Important residue (active site in E.coli) is residue 100 of the seed alignment. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 129547  Cd Length: 184  Bit Score: 258.55  E-value: 1.35e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     10 SALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAE 89
Cdd:TIGR00455   3 PAITKDERQALNGHRGVVIWLTGLSGSGKSTIANALEKKL-ESKGYRVYVLDGDNVRHGLNKDLGFSEEDRKENIRRIGE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     90 VAKLFADSNSIAITSFISPYRKDRDTARQLHEVATpgeetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGIS 169
Cdd:TIGR00455  82 VAKLFVRNGIIVITSFISPYRADRQMVRELIEKGE--------FIEVFVDCPLEVCEQRDPKGLYKKARNGEIKGFTGID 153

                         170       180       190
                  ....*....|....*....|....*....|.
gi 7387810    170 APYEAPANPEVHVKNYELPVQDAVKQIIDYL 200
Cdd:TIGR00455 154 SPYEAPENPEVVLDTDQNDREECVGQIIEKL 184
 
Name Accession Description Interval E-value
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 10-207 1.16e-109

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 312.02  E-value: 1.16e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   10 SALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAE 89
Cdd:COG0529   1 SAVTREERAALKGQKGFVVWFTGLSGSGKSTLANALERRL-FERGRHVYLLDGDNVRHGLNKDLGFSKEDRDENIRRIGE 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   90 VAKLFADSNSIAITSFISPYRKDRDTARQLHEvatPGEetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGIS 169
Cdd:COG0529  80 VAKLLADAGLIVLVAFISPYRADREEARELIG---EGE-----FIEVYVDTPLEVCEARDPKGLYAKARAGEIKNFTGID 151

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 7387810  170 APYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLP 207
Cdd:COG0529 152 DPYEAPENPELVLDTDKESVEESVEKILAYLEERGYIS 189
PRK03846 PRK03846
adenylylsulfate kinase; Provisional
 2-208 2.15e-97

adenylylsulfate kinase; Provisional


Pssm-ID: 179661  Cd Length: 198  Bit Score: 281.44  E-value: 2.15e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     2 STNITFHASALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLVrDRRVHAYRLDGDNIRFGLNKDLGFSEADRN 81
Cdd:PRK03846   1 DENIVWHQHPVTKAQREQLHGHKGVVLWFTGLSGSGKSTVAGALEEALH-ELGVSTYLLDGDNVRHGLCSDLGFSDADRK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    82 ENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEvatPGEetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGV 161
Cdd:PRK03846  80 ENIRRVGEVAKLMVDAGLVVLTAFISPHRAERQMVRERLG---EGE-----FIEVFVDTPLAICEARDPKGLYKKARAGE 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 7387810   162 IKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLPA 208
Cdd:PRK03846 152 IRNFTGIDSVYEAPESPEIHLDTGEQLVTNLVEQLLDYLRQRDIIRS 198
APS_kinase pfam01583
Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3 ...
 24-186 5.52e-97

Adenylylsulphate kinase; Enzyme that catalyzes the phosphorylation of adenylylsulphate to 3'-phosphoadenylylsulfate. This domain contains an ATP binding P-loop motif.


Pssm-ID: 396247 [Multi-domain]  Cd Length: 154  Bit Score: 278.82  E-value: 5.52e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     24 RGLTIWLTGLSASGKSTLAVELEHQLVrDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAIT 103
Cdd:pfam01583   1 RGCTIWLTGLSGAGKSTIANALERKLF-EQGRSVYVLDGDNVRHGLNKDLGFSEEDRTENIRRIGEVAKLFADAGLIVIT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    104 SFISPYRKDRDTARQLHEVAtpgeetglPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVK 183
Cdd:pfam01583  80 AFISPYREDREQARELHEEG--------KFIEVFVDTPLEVCEQRDPKGLYKKARAGEIKGFTGIDSPYEAPENPELVLD 151


                  ...
gi 7387810    184 NYE 186
Cdd:pfam01583 152 TDK 154
APSK cd02027
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5 ...
 27-183 2.35e-92

Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.


Pssm-ID: 238985 [Multi-domain]  Cd Length: 149  Bit Score: 266.65  E-value: 2.35e-92
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   27 TIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAITSFI 106
Cdd:cd02027   1 VIWLTGLSGSGKSTIARALEEKL-FQRGRPVYVLDGDNVRHGLNKDLGFSREDREENIRRIAEVAKLLADAGLIVIAAFI 79

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7387810  107 SPYRKDRDTARQLHEvatpgeetGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVK 183
Cdd:cd02027  80 SPYREDREAARKIIG--------GGDFLEVFVDTPLEVCEQRDPKGLYKKARAGEIKGFTGIDDPYEAPENPDLVLD 148
PRK05506 PRK05506
bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional
 2-206 2.68e-90

bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional


Pssm-ID: 180120 [Multi-domain]  Cd Length: 632  Bit Score: 277.20  E-value: 2.68e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     2 STNITFHASALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLVrDRRVHAYRLDGDNIRFGLNKDLGFSEADRN 81
Cdd:PRK05506 437 ATNVHWQASDVSREARAARKGQKPATVWFTGLSGSGKSTIANLVERRLH-ALGRHTYLLDGDNVRHGLNRDLGFSDADRV 515

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    82 ENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEVAtpgeetglPFVEVYVDVPVEVAEQRDPKGLYKKAREGV 161
Cdd:PRK05506 516 ENIRRVAEVARLMADAGLIVLVSFISPFREERELARALHGEG--------EFVEVFVDTPLEVCEARDPKGLYAKARAGE 587

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 7387810   162 IKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYL 206
Cdd:PRK05506 588 IKNFTGIDSPYEAPENPELRLDTTGRSPEELAEQVLELLRRRGAI 632
apsK TIGR00455
adenylyl-sulfate kinase; This protein, adenylylsulfate kinase, is often found as a fusion ...
 10-200 1.35e-88

adenylyl-sulfate kinase; This protein, adenylylsulfate kinase, is often found as a fusion protein with sulfate adenylyltransferase. Important residue (active site in E.coli) is residue 100 of the seed alignment. [Central intermediary metabolism, Sulfur metabolism]


Pssm-ID: 129547  Cd Length: 184  Bit Score: 258.55  E-value: 1.35e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     10 SALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAE 89
Cdd:TIGR00455   3 PAITKDERQALNGHRGVVIWLTGLSGSGKSTIANALEKKL-ESKGYRVYVLDGDNVRHGLNKDLGFSEEDRKENIRRIGE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     90 VAKLFADSNSIAITSFISPYRKDRDTARQLHEVATpgeetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGIS 169
Cdd:TIGR00455  82 VAKLFVRNGIIVITSFISPYRADRQMVRELIEKGE--------FIEVFVDCPLEVCEQRDPKGLYKKARNGEIKGFTGID 153

                         170       180       190
                  ....*....|....*....|....*....|.
gi 7387810    170 APYEAPANPEVHVKNYELPVQDAVKQIIDYL 200
Cdd:TIGR00455 154 SPYEAPENPEVVLDTDQNDREECVGQIIEKL 184
PRK00889 PRK00889
adenylylsulfate kinase; Provisional
 22-207 2.87e-68

adenylylsulfate kinase; Provisional


Pssm-ID: 179157  Cd Length: 175  Bit Score: 206.80  E-value: 2.87e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    22 NQRGLTIWLTGLSASGKSTLAVELEHQL-VRDRRVHAyrLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSI 100
Cdd:PRK00889   1 KQRGVTVWFTGLSGAGKTTIARALAEKLrEAGYPVEV--LDGDAVRTNLSKGLGFSKEDRDTNIRRIGFVANLLTRHGVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   101 AITSFISPYRKDRDTARQlhevATPGeetglpFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEV 180
Cdd:PRK00889  79 VLVSAISPYRETREEVRA----NIGN------FLEVFVDAPLEVCEQRDVKGLYAKARAGEIKHFTGIDDPYEPPLNPEV 148

                        170       180
                 ....*....|....*....|....*..
gi 7387810   181 HVKNYELPVQDAVKQIIDYLDTKGYLP 207
Cdd:PRK00889 149 ECRTDLESLEESVDKVLQKLEELGYLV 175
PRK05537 PRK05537
bifunctional sulfate adenylyltransferase/adenylylsulfate kinase;
21-206 6.01e-63

bifunctional sulfate adenylyltransferase/adenylylsulfate kinase;


Pssm-ID: 180124 [Multi-domain]  Cd Length: 568  Bit Score: 204.52  E-value: 6.01e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    21 RNQRGLTIWLTGLSASGKSTLAVELEHQL--VRDRRVHAyrLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSN 98
Cdd:PRK05537 388 RHKQGFTVFFTGLSGAGKSTIAKALMVKLmeMRGRPVTL--LDGDVVRKHLSSELGFSKEDRDLNILRIGFVASEITKNG 465

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    99 SIAITSFISPYRKDRDTARQLHEvatpgeETGlPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANP 178
Cdd:PRK05537 466 GIAICAPIAPYRATRREVREMIE------AYG-GFIEVHVATPLEVCEQRDRKGLYAKAREGKIKGFTGISDPYEPPANP 538

                        170       180
                 ....*....|....*....|....*...
gi 7387810   179 EVHVKNYELPVQDAVKQIIDYLDTKGYL 206
Cdd:PRK05537 539 ELVIDTTNVTPDECAHKILLYLEEKGYL 566
PRK05541 PRK05541
adenylylsulfate kinase; Provisional
 23-204 6.14e-24

adenylylsulfate kinase; Provisional


Pssm-ID: 235498  Cd Length: 176  Bit Score: 93.20  E-value: 6.14e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    23 QRGLTIWLTGLSASGKSTLAVELEHQLvRDRRVHAYRLDGDNIR--FGLNkdlGFSEADRNENIRRIAEVAKLFADSNSI 100
Cdd:PRK05541   5 PNGYVIWITGLAGSGKTTIAKALYERL-KLKYSNVIYLDGDELReiLGHY---GYDKQSRIEMALKRAKLAKFLADQGMI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   101 AITSFISPYRKDRDTARQLhevatpgeetgLP-FVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPE 179
Cdd:PRK05541  81 VIVTTISMFDEIYAYNRKH-----------LPnYFEVYLKCDMEELIRRDQKGLYTKALKGEIKNVVGVDIPFDEPKADL 149

                        170       180
                 ....*....|....*....|....*
gi 7387810   180 VHVKNYELPVQDAVKQIIDYLDTKG 204
Cdd:PRK05541 150 VIDNSCRTSLDEKVDLILNKLKLRL 174
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
28-196 8.32e-10

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 55.30  E-value: 8.32e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   28 IWLTGLSASGKSTLAVELEhqlvrdRRVHAYRLDGDNIRFGLnKDLGFSEADRNENIR-----RIAEVAKLFADSNSIAI 102
Cdd:COG0645   2 ILVCGLPGSGKSTLARALA------ERLGAVRLRSDVVRKRL-FGAGLAPLERSPEATartyaRLLALARELLAAGRSVI 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810  103 TSFISPYRKDRDTARQLhevatpGEETGLPFVEVYVDVPVEVA----EQRDPKGLYKKAREGVIKEFTGISAPYEAPANP 178
Cdd:COG0645  75 LDATFLRRAQREAFRAL------AEEAGAPFVLIWLDAPEEVLrerlEARNAEGGDSDATWEVLERQLAFEEPLTEDEGF 148

                       170
                ....*....|....*...
gi 7387810  179 EVHVKNYELPvqDAVKQI 196
Cdd:COG0645 149 LLVVDTSGLE--EALAAL 164
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 28-148 8.33e-09

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 52.31  E-value: 8.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810     28 IWLTGLSASGKSTLAVELEhqlvrdRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADS------NSIA 101
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLL------EELGAVRLSSDDERKRLFGEGRPSISYYTDATDRTYERLHELARIalragrPVIL 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 7387810    102 ITSFISpyRKDRDTARQLhevatpGEETGLPFVEVYVDVPVEVAEQR 148
Cdd:pfam13671  76 DATNLR--RDERARLLAL------AREYGVPVRIVVFEAPEEVLRER 114
COG4639 COG4639
Predicted kinase [General function prediction only];
30-164 4.72e-07

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 47.52  E-value: 4.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   30 LTGLSASGKSTLAveleHQLVRDRRVhayrLDGDNIRfglnKDLGFSEADRNENiRRIAEVAKLFADSNSIAITSFI--- 106
Cdd:COG4639   7 LIGLPGSGKSTFA----RRLFAPTEV----VSSDDIR----ALLGGDENDQSAW-GDVFQLAHEIARARLRAGRLTVvda 73

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 7387810  107 -SPYRKDRdtaRQLHEVATpgeETGLPFVEVYVDVPVEVAEQRDpkglykKAREGVIKE 164
Cdd:COG4639  74 tNLQREAR---RRLLALAR---AYGALVVAVVLDVPLEVCLARN------AARDRQVPE 120
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
 24-204 1.24e-06

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 47.03  E-value: 1.24e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   24 RGLTIWLTGLSASGKSTLAVEL--EHQLVRDRRVHayrLDGDNIRFGLNKDLGFSEADRnENIRRIAE-VAKLFADSNSI 100
Cdd:COG4088   3 SPMLLILTGPPGSGKTTFAKALaqRLYAEGIAVAL---LHSDDFRRFLVNESFPKETYE-EVVEDVRTtTADNALDNGYS 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810  101 AITSFISPYRKDRDTARQLHEVATpgeetglPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEaPANPEV 180
Cdd:COG4088  79 VIVDGTFYYRSWQRDFRNLAKHKA-------PIHIIYLKAPLETALRRNRERGEPIPERVIARMYRKFDKPGT-KDRPDL 150

                       170       180
                ....*....|....*....|....
gi 7387810  181 HVKNYELPVQDAVKQIIDYLDTKG 204
Cdd:COG4088 151 VIDTTEDSVSETLDAILKAIETWG 174
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 30-160 1.42e-05

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 43.40  E-value: 1.42e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810   30 LTGLSASGKSTLAVELEHQLvrdrrvHAYRLDGDNIRFGLNKDL-----GFSEADRN---ENIRRIAEVAKLFADSNSIA 101
Cdd:cd02021   4 VMGVSGSGKSTVGKALAERL------GAPFIDGDDLHPPANIAKmaagiPLNDEDRWpwlQALTDALLAKLASAGEGVVV 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 7387810  102 ITSFISpyRKDRDTARQLHevatpgeeTGLPFVEVYVDVPVEVAEQRDpkglykKAREG 160
Cdd:cd02021  78 ACSALK--RIYRDILRGGA--------ANPRVRFVHLDGPREVLAERL------AARKG 120
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 27-62 7.01e-05

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 39.63  E-value: 7.01e-05
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 7387810   27 TIWLTGLSASGKSTLAVELEHQLvrdRRVHAYRLDG 62
Cdd:cd02019   1 IIAITGGSGSGKSTVAKKLAEQL---GGRSVVVLDE 33
pseT PHA02530
polynucleotide kinase; Provisional
 28-164 6.44e-03

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 36.54  E-value: 6.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7387810    28 IWLT-GLSASGKSTLAVELEHQLVRdrrvhAYRLDGDNIR---FGLNKDLGFSEADRNENIRRIAE----VAKLFADSNS 99
Cdd:PHA02530   4 IILTvGVPGSGKSTWAREFAAKNPK-----AVNVNRDDLRqslFGHGEWGEYKFTKEKEDLVTKAQeaaaLAALKSGKSV 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7387810   100 IAITSFISPYRKdrdtaRQLHEVATpgeETGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKE 164
Cdd:PHA02530  79 IISDTNLNPERR-----RKWKELAK---ELGAEFEEKVFDVPVEELVKRNRKRGERAVPEDVLRS 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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