NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|341940937|sp|Q0ZCJ7|]
View 

RecName: Full=MEF2-activating motif and SAP domain-containing transcriptional regulator; AltName: Full=MEF2-activating SAP transcriptional regulatory protein

Protein Classification

SAP domain-containing protein( domain architecture ID 10488483)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

CATH:  1.10.720.30
Gene Ontology:  GO:0003676|GO:0003700
PubMed:  10694879
SCOP:  4002795

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 165-194 2.45e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


:

Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.32  E-value: 2.45e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 341940937  165 LEELTVSELRQQLRLRGLPVSGTKAMLLER 194
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIER 30
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 165-194 2.45e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.32  E-value: 2.45e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 341940937  165 LEELTVSELRQQLRLRGLPVSGTKAMLLER 194
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIER 30
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
165-194 1.82e-06

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 44.01  E-value: 1.82e-06
                           10        20        30
                   ....*....|....*....|....*....|
gi 341940937   165 LEELTVSELRQQLRLRGLPVSGTKAMLLER 194
Cdd:smart00513   1 LAKLKVSELKDELKKRGLSTSGTKAELVDR 30
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
 142-195 8.70e-04

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 41.75  E-value: 8.70e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 341940937 142 KPSSAGVSSPSPPSHKLeLQTLKLEELTVSELRQQLRLRGLPVSGTKAMLLERM 195
Cdd:PLN03124  57 RRERQDDGDDEPVSPKR-IAIDEVKGMTVRELREAASERGLATTGRKKDLLERL 109
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 165-194 2.45e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.32  E-value: 2.45e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 341940937  165 LEELTVSELRQQLRLRGLPVSGTKAMLLER 194
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIER 30
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
165-194 1.82e-06

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 44.01  E-value: 1.82e-06
                           10        20        30
                   ....*....|....*....|....*....|
gi 341940937   165 LEELTVSELRQQLRLRGLPVSGTKAMLLER 194
Cdd:smart00513   1 LAKLKVSELKDELKKRGLSTSGTKAELVDR 30
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
 142-195 8.70e-04

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 41.75  E-value: 8.70e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 341940937 142 KPSSAGVSSPSPPSHKLeLQTLKLEELTVSELRQQLRLRGLPVSGTKAMLLERM 195
Cdd:PLN03124  57 RRERQDDGDDEPVSPKR-IAIDEVKGMTVRELREAASERGLATTGRKKDLLERL 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH