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Conserved domains on  [gi|292630954|sp|Q0WT31|]
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RecName: Full=Probable methyltransferase PMT25

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 18808940)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Arabidopsis thaliana methyltransferase PMT25

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008757|GO:0008168|GO:1904047
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 250-754 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


:

Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 939.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  250 DYIPCLDNWQAIKKLHTTMHYEHRERHCP--EESPHCLVSLPDGYKRSIKWPKSREKIWYNNVPHTKLAEIKGHQNWVKM 327
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSRERMEHRERHCPppEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  328 SGEHLTFPGGGTQFKNGALHYIDFIQQSHPAIAWGNRTRVILDVGCGVASFGGYLFERDVLALSFAPKDEHEAQVQFALE 407
Cdd:pfam03141  81 EGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIAWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFALE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  408 RGIPAMLNVMGTKRLPFPGSVFDLIHCARCRVPWHIEGGKLLLELNRALRPGGFFVWSATPVY-RKNEEDSGIWKAMSEL 486
Cdd:pfam03141 161 RGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWKEMEDL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  487 TKAMCWKLVTIKKDklnevgAAIYQKPTSNKCYNKR-PQNEPPLCKDSDDQNAAWNVPLEACMHKVTEDSSKRGAVWPNM 565
Cdd:pfam03141 241 TKSLCWKLVAKKGD------IAIWQKPLNNSCYNKRePGKKPPLCKDSDDPDAAWYVPMEACITPLPEVSHEVGGGWPEP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  566 WPERVETAPEWLdsQEGVYGKPAPEDFTADQEKWKTIVSKAY-LNDMGIDWSNVRNVMDMRAVYGGFAAALKDLKLWVMN 644
Cdd:pfam03141 315 WPARLTAVPPRL--SSGQIGGVSPESFKADTELWKKRVNKYKrLLKLGIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMN 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  645 VVPVDAPDTLPIIYERGLFGIYHDWCESFNTYPRTYDLLHADHLFSTLRKRCNLVSVMAEIDRILRPQGTFIIRDDMETL 724
Cdd:pfam03141 393 VVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 292630954  725 GEVEKMVKSMKWKVKMTQSKD----NEGLLSIEK 754
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDgphvPEKILIAQK 506
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 54-237 2.36e-08

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 57.72  E-value: 2.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   54 DTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGE 133
Cdd:COG5271   508 ELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADET 587

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  134 KEKNVKEvgSESDETTQKEKTQLEESTEENKSE-DGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKESSTGDGA 212
Cdd:COG5271   588 EESADES--EEAEASEDEAAEEEEADDDEADADaDGAADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASADES 665

                         170       180
                  ....*....|....*....|....*
gi 292630954  213 WstQLVESQNEKKAQQSSISKDQSS 237
Cdd:COG5271   666 E--EEAEDESETSSEDAEEDADAAA 688
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 250-754 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 939.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  250 DYIPCLDNWQAIKKLHTTMHYEHRERHCP--EESPHCLVSLPDGYKRSIKWPKSREKIWYNNVPHTKLAEIKGHQNWVKM 327
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSRERMEHRERHCPppEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  328 SGEHLTFPGGGTQFKNGALHYIDFIQQSHPAIAWGNRTRVILDVGCGVASFGGYLFERDVLALSFAPKDEHEAQVQFALE 407
Cdd:pfam03141  81 EGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIAWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFALE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  408 RGIPAMLNVMGTKRLPFPGSVFDLIHCARCRVPWHIEGGKLLLELNRALRPGGFFVWSATPVY-RKNEEDSGIWKAMSEL 486
Cdd:pfam03141 161 RGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWKEMEDL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  487 TKAMCWKLVTIKKDklnevgAAIYQKPTSNKCYNKR-PQNEPPLCKDSDDQNAAWNVPLEACMHKVTEDSSKRGAVWPNM 565
Cdd:pfam03141 241 TKSLCWKLVAKKGD------IAIWQKPLNNSCYNKRePGKKPPLCKDSDDPDAAWYVPMEACITPLPEVSHEVGGGWPEP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  566 WPERVETAPEWLdsQEGVYGKPAPEDFTADQEKWKTIVSKAY-LNDMGIDWSNVRNVMDMRAVYGGFAAALKDLKLWVMN 644
Cdd:pfam03141 315 WPARLTAVPPRL--SSGQIGGVSPESFKADTELWKKRVNKYKrLLKLGIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMN 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  645 VVPVDAPDTLPIIYERGLFGIYHDWCESFNTYPRTYDLLHADHLFSTLRKRCNLVSVMAEIDRILRPQGTFIIRDDMETL 724
Cdd:pfam03141 393 VVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 292630954  725 GEVEKMVKSMKWKVKMTQSKD----NEGLLSIEK 754
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDgphvPEKILIAQK 506
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 54-237 2.36e-08

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 57.72  E-value: 2.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   54 DTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGE 133
Cdd:COG5271   508 ELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADET 587

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  134 KEKNVKEvgSESDETTQKEKTQLEESTEENKSE-DGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKESSTGDGA 212
Cdd:COG5271   588 EESADES--EEAEASEDEAAEEEEADDDEADADaDGAADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASADES 665

                         170       180
                  ....*....|....*....|....*
gi 292630954  213 WstQLVESQNEKKAQQSSISKDQSS 237
Cdd:COG5271   666 E--EEAEDESETSSEDAEEDADAAA 688
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 368-463 2.41e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 53.46  E-value: 2.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 368 ILDVGCGVASFGGYLFERD--VLALsfapkDEHEAQVQFALERGIPAMLNVMGTK----RLPFPGSVFDLIHCARcrVPW 441
Cdd:COG2226   26 VLDLGCGTGRLALALAERGarVTGV-----DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSF--VLH 98

                         90       100
                 ....*....|....*....|...
gi 292630954 442 HIEG-GKLLLELNRALRPGGFFV 463
Cdd:COG2226   99 HLPDpERALAEIARVLKPGGRLV 121
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 56-241 3.31e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 57.31  E-value: 3.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954    56 AKDVSKNDLRKEEGDrDPKNFSDEKNEENEAATENNQVKTD-SENSAEGNQVNESSGEKTEAGEERKES-DDNNGDGDGE 133
Cdd:TIGR00927  622 AKVMALGDLSKGDVA-EAEHTGERTGEEGERPTEAEGENGEeSGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIE 700

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   134 KEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSK-EVFPAGDQAEITKESSTGDGA 212
Cdd:TIGR00927  701 AKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEgDRKETEHEGETEAEGKEDEDE 780

                          170       180       190
                   ....*....|....*....|....*....|..
gi 292630954   213 WSTQL---VESQNEKKAQQSSISKDQSSYGWK 241
Cdd:TIGR00927  781 GEIQAgedGEMKGDEGAEGKVEHEGETEAGEK 812
PHA03169 PHA03169
hypothetical protein; Provisional
 65-311 7.20e-08

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 55.36  E-value: 7.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  65 RKEEGDRDPKNFSDEKNEENEAATENNQvkTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKEKNVKEVGSE 144
Cdd:PHA03169  97 SESVGSPTPSPSGSAEELASGLSPENTS--GSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDS 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 145 SDETTQKEKTQLEESTEENKSEDGngneEKAEENASETEESTEksskevfPAGDQAEITKESSTGDGAWSTQLVESQNEK 224
Cdd:PHA03169 175 PEEPEPPTSEPEPDSPGPPQSETP----TSSPPPQSPPDEPGE-------PQSPTPQQAPSPNTQQAVEHEDEPTEPERE 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 225 KAQQSSISkdQSSY---GWKTcnvTAGPDYIPCLdnwqaikKLHTTMHYEHRERhcpeesphclvsLPDGYKRSIKWPK- 300
Cdd:PHA03169 244 GPPFPGHR--SHSYtvvGWKP---STRPGGVPKL-------CLRCTSHPSHRSR------------LPEGQQSEDKVPRk 299

                        250
                 ....*....|...
gi 292630954 301 --SREKIWYNNVP 311
Cdd:PHA03169 300 yqARRRFFRQVLP 312
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-231 2.22e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.98  E-value: 2.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 791

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNV-----KEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKE 192
Cdd:NF033609 792 SDSDSDsDSDSDSDSDSDSDSdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNN 871

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 292630954 193 VFPAGDQAEITKESSTGDGAWSTQ-LVESQNEKKAQQSSI 231
Cdd:NF033609 872 VVPPNSPKNGTNASNKNEAKDSKEpLPDTGSEDEANTSLI 911
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-237 3.23e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.60  E-value: 3.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 626 SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 705

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNV-KEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPA 196
Cdd:NF033609 706 SDSDSDsDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 785

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 292630954 197 GDQAEITKESSTGDgawSTQLVESQNEKKAQQSSISKDQSS 237
Cdd:NF033609 786 SDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSD 823
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-236 4.59e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 608 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 687

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNvkevgSESDETTQKEKTQLEESTEENKSE-DGNGNEEKAEENASETEESTEKSSKEVFPA 196
Cdd:NF033609 688 SDSDSDsDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 762

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 292630954 197 GDQAEITKESSTGDGAWSTQLVESQNEKKAQQSSISKDQS 236
Cdd:NF033609 763 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 802
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-236 7.26e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 7.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 590 SGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 669

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNvKEVGSESDETTQKEKTQLEESTEENKSeDGNGNEEKAEENASETEESTEKSSKEVFPAG 197
Cdd:NF033609 670 SDSDSDsDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 747

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 292630954 198 DQAEITKESSTGDGAWSTQLVESQNEKKAQQSSISKDQS 236
Cdd:NF033609 748 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 786
PRK08317 PRK08317
hypothetical protein; Provisional
 353-460 4.04e-04

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 42.62  E-value: 4.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 353 QQSHPAIAWGNRTRViLDVGCG----VASFGGYLF-ERDVLALsfapkDEHEAQVQFALERGIPAMLNV----MGTKRLP 423
Cdd:PRK08317   9 ARTFELLAVQPGDRV-LDVGCGpgndARELARRVGpEGRVVGI-----DRSEAMLALAKERAAGLGPNVefvrGDADGLP 82

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 292630954 424 FPGSVFDLihCARCRVPWHIEG-GKLLLELNRALRPGG 460
Cdd:PRK08317  83 FPDGSFDA--VRSDRVLQHLEDpARALAEIARVLRPGG 118
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 345-465 5.55e-04

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 42.27  E-value: 5.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  345 ALHYIDFIQQSHPAIawgnrTRVILDVGCGVASFGGYLFER----DVLALSFAPKDEHEA------QVQFalergipaml 414
Cdd:TIGR02072  20 AKRLLALLKEKGIFI-----PASVLDIGCGTGYLTRALLKRfpqaEFIALDISAGMLAQAktklseNVQF---------- 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 292630954  415 nVMG-TKRLPFPGSVFDLIHCARCrVPWHIEGGKLLLELNRALRPGGFFVWS 465
Cdd:TIGR02072  85 -ICGdAEKLPLEDSSFDLIVSNLA-LQWCDDLSQALSELARVLKPGGLLAFS 134
DMP1 pfam07263
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ...
 40-236 1.93e-03

Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.


Pssm-ID: 462128 [Multi-domain]  Cd Length: 519  Bit Score: 41.45  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   40 SWSApADSAGYSSTDTAKDVSKNDlrkEEGDRDPKnfSDEKNEENEAATEN-NQVKTDSENSAEG-NQVNESSGEKTEAG 117
Cdd:pfam07263 306 SQSR-EDSKSESQEDSEESQSQED---SQNSQDPS--SESSQEADLPSQESsSESQEEVVSESRGdNPDNTSSSEEDQED 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  118 EERKESDDNNGDGDGEKEKNVKEVGSESDETTqKEKTQLEESTEENKSEdgngneekAEENASETEESTEKSSKEVFPAG 197
Cdd:pfam07263 380 SDSSEEDSLSTFSSSESESREEQADSESNESL-RSSEESPESSEDENSS--------SQEGLQSHSASTESQSEESQSEQ 450

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 292630954  198 D-QAEITKESSTGDGAWStqlVESQNEKKAQQSSISKDQS 236
Cdd:pfam07263 451 DsQSEEDDESDSQDSSRS---KEDSNSTESTSSSEEDGQS 487
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 250-754 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 939.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  250 DYIPCLDNWQAIKKLHTTMHYEHRERHCP--EESPHCLVSLPDGYKRSIKWPKSREKIWYNNVPHTKLAEIKGHQNWVKM 327
Cdd:pfam03141   1 DYIPCLDNKRAIKFLLSRERMEHRERHCPppEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  328 SGEHLTFPGGGTQFKNGALHYIDFIQQSHPAIAWGNRTRVILDVGCGVASFGGYLFERDVLALSFAPKDEHEAQVQFALE 407
Cdd:pfam03141  81 EGDKFTFPGGGTQFPHGADQYIDFIAQMIPDIAWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFALE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  408 RGIPAMLNVMGTKRLPFPGSVFDLIHCARCRVPWHIEGGKLLLELNRALRPGGFFVWSATPVY-RKNEEDSGIWKAMSEL 486
Cdd:pfam03141 161 RGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYaRTEEDLQEIWKEMEDL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  487 TKAMCWKLVTIKKDklnevgAAIYQKPTSNKCYNKR-PQNEPPLCKDSDDQNAAWNVPLEACMHKVTEDSSKRGAVWPNM 565
Cdd:pfam03141 241 TKSLCWKLVAKKGD------IAIWQKPLNNSCYNKRePGKKPPLCKDSDDPDAAWYVPMEACITPLPEVSHEVGGGWPEP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  566 WPERVETAPEWLdsQEGVYGKPAPEDFTADQEKWKTIVSKAY-LNDMGIDWSNVRNVMDMRAVYGGFAAALKDLKLWVMN 644
Cdd:pfam03141 315 WPARLTAVPPRL--SSGQIGGVSPESFKADTELWKKRVNKYKrLLKLGIDWGKVRNVMDMNAGFGGFAAALIDLPVWVMN 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  645 VVPVDAPDTLPIIYERGLFGIYHDWCESFNTYPRTYDLLHADHLFSTLRKRCNLVSVMAEIDRILRPQGTFIIRDDMETL 724
Cdd:pfam03141 393 VVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSVDVL 472

                         490       500       510
                  ....*....|....*....|....*....|....
gi 292630954  725 GEVEKMVKSMKWKVKMTQSKD----NEGLLSIEK 754
Cdd:pfam03141 473 DKVKKIAKAMRWEVRMTDTEDgphvPEKILIAQK 506
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 54-237 2.36e-08

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 57.72  E-value: 2.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   54 DTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGE 133
Cdd:COG5271   508 ELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADET 587

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  134 KEKNVKEvgSESDETTQKEKTQLEESTEENKSE-DGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKESSTGDGA 212
Cdd:COG5271   588 EESADES--EEAEASEDEAAEEEEADDDEADADaDGAADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASADES 665

                         170       180
                  ....*....|....*....|....*
gi 292630954  213 WstQLVESQNEKKAQQSSISKDQSS 237
Cdd:COG5271   666 E--EEAEDESETSSEDAEEDADAAA 688
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 368-463 2.41e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 53.46  E-value: 2.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 368 ILDVGCGVASFGGYLFERD--VLALsfapkDEHEAQVQFALERGIPAMLNVMGTK----RLPFPGSVFDLIHCARcrVPW 441
Cdd:COG2226   26 VLDLGCGTGRLALALAERGarVTGV-----DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSF--VLH 98

                         90       100
                 ....*....|....*....|...
gi 292630954 442 HIEG-GKLLLELNRALRPGGFFV 463
Cdd:COG2226   99 HLPDpERALAEIARVLKPGGRLV 121
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 56-241 3.31e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 57.31  E-value: 3.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954    56 AKDVSKNDLRKEEGDrDPKNFSDEKNEENEAATENNQVKTD-SENSAEGNQVNESSGEKTEAGEERKES-DDNNGDGDGE 133
Cdd:TIGR00927  622 AKVMALGDLSKGDVA-EAEHTGERTGEEGERPTEAEGENGEeSGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIE 700

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   134 KEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSK-EVFPAGDQAEITKESSTGDGA 212
Cdd:TIGR00927  701 AKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEgDRKETEHEGETEAEGKEDEDE 780

                          170       180       190
                   ....*....|....*....|....*....|..
gi 292630954   213 WSTQL---VESQNEKKAQQSSISKDQSSYGWK 241
Cdd:TIGR00927  781 GEIQAgedGEMKGDEGAEGKVEHEGETEAGEK 812
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 369-463 4.47e-08

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 51.13  E-value: 4.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  369 LDVGCGVASFGGYLFER--DVLALSFAPKdeheaQVQFALERGIPAMLN--VMGTKRLPFPGSVFDLIHCarCRVPWHIE 444
Cdd:pfam08241   1 LDVGCGTGLLTELLARLgaRVTGVDISPE-----MLELAREKAPREGLTfvVGDAEDLPFPDNSFDLVLS--SEVLHHVE 73

                          90       100
                  ....*....|....*....|
gi 292630954  445 -GGKLLLELNRALRPGGFFV 463
Cdd:pfam08241  74 dPERALREIARVLKPGGILI 93
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 368-460 6.26e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 51.03  E-value: 6.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  368 ILDVGCGVASFGGYL---FERDVLALsfapkDEHEAQVQFALERGIPAMLNV----MGTKRLPFPGSVFDLIHCARC-RV 439
Cdd:pfam13649   1 VLDLGCGTGRLTLALarrGGARVTGV-----DLSPEMLERARERAAEAGLNVefvqGDAEDLPFPDGSFDLVVSSGVlHH 75

                          90       100
                  ....*....|....*....|.
gi 292630954  440 PWHIEGGKLLLELNRALRPGG 460
Cdd:pfam13649  76 LPDPDLEAALREIARVLKPGG 96
PHA03169 PHA03169
hypothetical protein; Provisional
 65-311 7.20e-08

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 55.36  E-value: 7.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  65 RKEEGDRDPKNFSDEKNEENEAATENNQvkTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKEKNVKEVGSE 144
Cdd:PHA03169  97 SESVGSPTPSPSGSAEELASGLSPENTS--GSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDS 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 145 SDETTQKEKTQLEESTEENKSEDGngneEKAEENASETEESTEksskevfPAGDQAEITKESSTGDGAWSTQLVESQNEK 224
Cdd:PHA03169 175 PEEPEPPTSEPEPDSPGPPQSETP----TSSPPPQSPPDEPGE-------PQSPTPQQAPSPNTQQAVEHEDEPTEPERE 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 225 KAQQSSISkdQSSY---GWKTcnvTAGPDYIPCLdnwqaikKLHTTMHYEHRERhcpeesphclvsLPDGYKRSIKWPK- 300
Cdd:PHA03169 244 GPPFPGHR--SHSYtvvGWKP---STRPGGVPKL-------CLRCTSHPSHRSR------------LPEGQQSEDKVPRk 299

                        250
                 ....*....|...
gi 292630954 301 --SREKIWYNNVP 311
Cdd:PHA03169 300 yqARRRFFRQVLP 312
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 51-236 1.24e-07

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 55.39  E-value: 1.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954    51 SSTDTAKDVSKNDLRKEEGDRdPKNFSDEKNEENEAATEN-NQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGD 129
Cdd:TIGR00927  631 SKGDVAEAEHTGERTGEEGER-PTEAEGENGEESGGEAEQeGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGE 709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   130 GDGEKEKNVKEVGSESDETTQK----EKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGD-QAEITK 204
Cdd:TIGR00927  710 TEAEEVEHEGETEAEGTEDEGEietgEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEiQAGEDG 789

                          170       180       190
                   ....*....|....*....|....*....|..
gi 292630954   205 ESSTGDGAwsTQLVESQNEKKAQQSSISKDQS 236
Cdd:TIGR00927  790 EMKGDEGA--EGKVEHEGETEAGEKDEHEGQS 819
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 78-194 1.43e-07

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 55.18  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   78 DEKNEENEAATENNQVKTDSENSAEgnqVNESSGEKTEAGEER--KESDDNNGDgdgEKEKNVKEVGSES-DETTQKEKT 154
Cdd:PTZ00341 1020 EEYDEENVEEVEENVEEYDEENVEE---IEENAEENVEENIEEniEEYDEENVE---EIEENIEENIEENvEENVEENVE 1093

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 292630954  155 QLEESTEENKSEDGNGN-EEKAEENASETEESTEKSSKEVF 194
Cdd:PTZ00341 1094 EIEENVEENVEENAEENaEENAEENAEEYDDENPEEHNEEY 1134
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 78-224 3.84e-07

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 54.02  E-value: 3.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   78 DEKNEEN-EAATENNqVKTDSENSAEGNqVNESSGEKTEAGEERKESDDNNGDGDGEK--EKNVKEVGSESDETTQKEKT 154
Cdd:PTZ00341  992 EENVEENvEENIEEN-VEENVEENIEEN-VEEYDEENVEEVEENVEEYDEENVEEIEEnaEENVEENIEENIEEYDEENV 1069

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 292630954  155 Q-LEESTEENKSEDgngNEEKAEENASETEESTEKSSKEvfPAGDQAEITKESSTGDgaWSTQLVESQNEK 224
Cdd:PTZ00341 1070 EeIEENIEENIEEN---VEENVEENVEEIEENVEENVEE--NAEENAEENAEENAEE--YDDENPEEHNEE 1133
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 43-237 7.25e-07

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 53.09  E-value: 7.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   43 APADSAGYSSTDTAKDVSKNDLrKEEGDRDPKNFSDEKNEENEAATENnqVKTDSENSAEGNQVNESSGEKTEAGEERKE 122
Cdd:COG5271   535 ALEDETEGEENAPGSDQDADET-DEPEATAEEDEPDEAEAETEDATEN--ADADETEESADESEEAEASEDEAAEEEEAD 611

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  123 SDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEE----KAEENASETEESTEKSSKEVFPA-- 196
Cdd:COG5271   612 DDEADADADGAADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASAdeseEEAEDESETSSEDAEEDADAAAAea 691

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 292630954  197 -GDQAEIT---KESSTGDGAWSTQLVESQNEKKAQQSSISKDQSS 237
Cdd:COG5271   692 sDDEEETEeadEDAETASEEADAEEADTEADGTAEEAEEAAEEAE 736
COG5137 COG5137
Histone chaperone involved in gene silencing [Transcription / Chromatin structure and dynamics] ...
 67-191 9.02e-07

Histone chaperone involved in gene silencing [Transcription / Chromatin structure and dynamics];


Pssm-ID: 227466 [Multi-domain]  Cd Length: 279  Bit Score: 51.15  E-value: 9.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  67 EEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEA-GEERKESDDNNGDGDGEKEKNVKEVGSEs 145
Cdd:COG5137  162 EDNDEAPPAQPDVDNEEEERLEESDGREEEEDEEVGSDSYGEGNRELNEEeEEEAEGSDDGEDVVDYEGERIDKKQGEE- 240

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 292630954 146 dettqkektQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSK 191
Cdd:COG5137  241 ---------EEMEEEVINLFEIEWEEESPSEEVPRNNEESPAKKQK 277
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 78-192 1.38e-06

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 52.10  E-value: 1.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   78 DEKNEEN-EAATENNqVKTDSENSAEGNqVNESSGEKTEAGEERKESDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQL 156
Cdd:PTZ00341  968 EENVEENvEENVEEN-VEENVEENVEEN-VEENVEENIEENVEENVEENIEENVEEYDEENVEEVEENVEEYDEENVEEI 1045

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 292630954  157 EESTEENKSEDGNGN-EEKAEENASETEESTEKSSKE 192
Cdd:PTZ00341 1046 EENAEENVEENIEENiEEYDEENVEEIEENIEENIEE 1082
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 360-463 1.42e-06

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 48.09  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 360 AWGNRTRVILDVGCGVASFGGYLFER--DVLALsfapkDEHEAQVQFALERG--IPAMLNVMGTKRLPFPGSVFDLIHCa 435
Cdd:COG2227   20 RLLPAGGRVLDVGCGTGRLALALARRgaDVTGV-----DISPEALEIARERAaeLNVDFVQGDLEDLPLEDGSFDLVIC- 93

                         90       100
                 ....*....|....*....|....*....
gi 292630954 436 rCRVPWHIEG-GKLLLELNRALRPGGFFV 463
Cdd:COG2227   94 -SEVLEHLPDpAALLRELARLLKPGGLLL 121
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 45-230 1.48e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.94  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   45 ADSAGYSSTDTAKDVSKNDlRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESD 124
Cdd:COG5271   422 EDASAGETEDESTDVTSAE-DDIATDEEADSLADEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDA 500

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  125 DNNGDGDgekekNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITK 204
Cdd:COG5271   501 EAEADSD-----ELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAET 575

                         170       180
                  ....*....|....*....|....*.
gi 292630954  205 ESSTGDGAWSTQLVESQNEKKAQQSS 230
Cdd:COG5271   576 EDATENADADETEESADESEEAEASE 601
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 52-304 1.78e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 51.53  E-value: 1.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954    52 STDTAKDVSKNDLRKE-EGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQvNESSGEKTEAGEERKESDDNNGDG 130
Cdd:TIGR00927  673 TETKGENESEGEIPAErKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTE-DEGEIETGEEGEEVEDEGEGEAEG 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   131 DGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEkSSKEVFPAGDQAEITKESSTGD 210
Cdd:TIGR00927  752 KHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETE-AGEKDEHEGQSETQADDTEVKD 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   211 GAWSTQL-VESQNEKKAQQSSISKDQSSYGWKTcnvtagpdyipcLDNWQAIKKLHTTMHYEHRERHCPEESPHCLvslp 289
Cdd:TIGR00927  831 ETGEQELnAENQGEAKQDEKGVDGGGGSDGGDS------------EEEEEEEEEEEEEEEEEEEEEEEEEENEEPL---- 894

                          250
                   ....*....|....*
gi 292630954   290 dgykrSIKWPKSREK 304
Cdd:TIGR00927  895 -----SLEWPETRQK 904
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 45-201 3.62e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 50.78  E-value: 3.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   45 ADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEgNQVNESSGEKTEAGEERKESD 124
Cdd:COG5271   584 ADETEESADESEEAEASEDEAAEEEEADDDEADADADGAADEEETEEEAAEDEAAEPE-TDASEAADEDADAETEAEASA 662

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 292630954  125 DNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAE 201
Cdd:COG5271   663 DESEEEAEDESETSSEDAEEDADAAAAEASDDEEETEEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESAD 739
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 40-185 1.58e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 48.47  E-value: 1.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   40 SWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQ------VKTDSENSAEGNQVNESS-GE 112
Cdd:COG5271   688 AAEASDDEEETEEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESADEeaaslpDEADAEEEAEEAEEAEEDdAD 767

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 292630954  113 KTEAGEERKESDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEES 185
Cdd:COG5271   768 GLEEALEEEKADAEEAATDEEAEAAAEEKEKVADEDQDTDEDALLDEAEADEEEDLDGEDEETADEALEDIEA 840
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 43-239 1.87e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.45  E-value: 1.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954    43 APADSAGYSSTDTAKDVSKNDLRKEEGDRD-PKNFSDEKNEENEAATENNQVKTDSE---------NSAEGNQvNESSGE 112
Cdd:TIGR00927  655 AEGENGEESGGEAEQEGETETKGENESEGEiPAERKGEQEGEGEIEAKEADHKGETEaeevehegeTEAEGTE-DEGEIE 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   113 KTEAGEERKESDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEkSSKE 192
Cdd:TIGR00927  734 TGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETE-AGEK 812

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 292630954   193 VFPAGDQAEITKESSTGDGAWSTQL-VESQNEKKAQQSSISKDQSSYG 239
Cdd:TIGR00927  813 DEHEGQSETQADDTEVKDETGEQELnAENQGEAKQDEKGVDGGGGSDG 860
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-231 2.22e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.98  E-value: 2.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 791

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNV-----KEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKE 192
Cdd:NF033609 792 SDSDSDsDSDSDSDSDSDSDSdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNN 871

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 292630954 193 VFPAGDQAEITKESSTGDGAWSTQ-LVESQNEKKAQQSSI 231
Cdd:NF033609 872 VVPPNSPKNGTNASNKNEAKDSKEpLPDTGSEDEANTSLI 911
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 61-229 2.63e-05

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 47.86  E-value: 2.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   61 KNDlrKEEGDRDPKNFSDekNEENEAATENNQVKTDSENSAEGNQvnessgEKTEAGEERKESDDNNGDGDGEKEKNVKE 140
Cdd:PTZ00341  900 KKD--KKAKKKDAKDLSG--NIAHEINLINKELKNQNENVPEHLK------EHAEANIEEDAEENVEEDAEENVEENVEE 969

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  141 VGSESDETTQKEktQLEESTEENKSEDGNGN-EEKAEENASE-TEESTEKSSKEVfpAGDQAEITKESSTGDGAWSTQLV 218
Cdd:PTZ00341  970 NVEENVEENVEE--NVEENVEENVEENVEENvEENIEENVEEnVEENIEENVEEY--DEENVEEVEENVEEYDEENVEEI 1045

                         170
                  ....*....|.
gi 292630954  219 ESQNEKKAQQS 229
Cdd:PTZ00341 1046 EENAEENVEEN 1056
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-237 3.23e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.60  E-value: 3.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 626 SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 705

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNV-KEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPA 196
Cdd:NF033609 706 SDSDSDsDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 785

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 292630954 197 GDQAEITKESSTGDgawSTQLVESQNEKKAQQSSISKDQSS 237
Cdd:NF033609 786 SDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSD 823
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 54-187 3.55e-05

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 47.47  E-value: 3.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   54 DTAKDVSKNDLRKEE-GDRDPKNFSDEKNEENEAATENNQVKTDSEnSAEGNQVNESSGEKT--EAGEERKESDDNNGDG 130
Cdd:PTZ00341  429 DGSEDESVEDNEEEHsGDANEEELSVDEHVEEHNADDSGEQQSDDE-SGEHQSVNEIVEEQSvnEHVEEPTVADIVEQET 507

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 292630954  131 DGEkekNVKEVGSESDETTQKEKTQLEEST--EENKSEDGNGNEEKAEENASETEESTE 187
Cdd:PTZ00341  508 VDE---HVEEPAVDENEEQQTADEHVEEPTiaEEHVEEEISTAEEHIEEPASDVQQDSE 563
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 52-234 4.07e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 47.32  E-value: 4.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   52 STDTAKDVSKNDLRKEE-GDRDPKNFSDEKNEENEAATENNQVKTDSENSAEgnqvnESSGEKTEAGEERKESDDNNGDG 130
Cdd:COG5271   675 TSSEDAEEDADAAAAEAsDDEEETEEADEDAETASEEADAEEADTEADGTAE-----EAEEAAEEAESADEEAASLPDEA 749

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  131 DGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAE--------ENASETEESTEKSSKEVFPAGDQAEI 202
Cdd:COG5271   750 DAEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAAEEkekvadedQDTDEDALLDEAEADEEEDLDGEDEE 829

                         170       180       190
                  ....*....|....*....|....*....|..
gi 292630954  203 TKESSTGDGAWSTQLVESQNEKKAQQSSISKD 234
Cdd:COG5271   830 TADEALEDIEAGIAEDDEEDDDAAAAKDVDAD 861
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-236 4.59e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 47.21  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 608 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 687

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNvkevgSESDETTQKEKTQLEESTEENKSE-DGNGNEEKAEENASETEESTEKSSKEVFPA 196
Cdd:NF033609 688 SDSDSDsDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 762

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 292630954 197 GDQAEITKESSTGDGAWSTQLVESQNEKKAQQSSISKDQS 236
Cdd:NF033609 763 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 802
PRK08581 PRK08581
amidase domain-containing protein;
24-237 6.36e-05

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 46.32  E-value: 6.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  24 VLLLSLCLVgTWMFMSSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENnqvkTDSENSAEG 103
Cdd:PRK08581   8 IYLLSTTLV-LPTLTSPTAYADDPQKDSTAKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDN----NDKKFSTID 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 104 NQVNESSGEKTEAGEERKESDDNNGDGDGEKEKNVKEVG------SESDETTQKEKTQLEESTEENKSeDGNGNEEKAEE 177
Cdd:PRK08581  83 SSTSDSNNIIDFIYKNLPQTNINQLLTKNKYDDNYSLTTliqnlfNLNSDISDYEQPRNSEKSTNDSN-KNSDSSIKNDT 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 292630954 178 NASETEESTEKSSKEvfpagDQAEITKESSTGDGAWSTQ-LVESQNEKKAQQSSISKDQSS 237
Cdd:PRK08581 162 DTQSSKQDKADNQKA-----PSSNNTKPSTSNKQPNSPKpTQPNQSNSQPASDDTANQKSS 217
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 67-237 7.01e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 46.55  E-value: 7.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   67 EEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEgNQVNESSGEKTEAGEERKESDDNNGDGdgekEKNVKEVGSESD 146
Cdd:COG5271   624 DEEETEEEAAEDEAAEPETDASEAADEDADAETEAE-ASADESEEEAEDESETSSEDAEEDADA----AAAEASDDEEET 698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  147 ETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKESSTGDGAWSTQLVESQNEKKA 226
Cdd:COG5271   699 EEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESADEEAASLPDEADAEEEAEEAEEAEEDDADGLEEALEEEKA 778

                         170
                  ....*....|.
gi 292630954  227 QQSSISKDQSS 237
Cdd:COG5271   779 DAEEAATDEEA 789
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-236 7.26e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 7.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  39 SSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGE 118
Cdd:NF033609 590 SGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 669

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 119 ERKESD-DNNGDGDGEKEKNvKEVGSESDETTQKEKTQLEESTEENKSeDGNGNEEKAEENASETEESTEKSSKEVFPAG 197
Cdd:NF033609 670 SDSDSDsDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 747

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 292630954 198 DQAEITKESSTGDGAWSTQLVESQNEKKAQQSSISKDQS 236
Cdd:NF033609 748 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 786
COG5137 COG5137
Histone chaperone involved in gene silencing [Transcription / Chromatin structure and dynamics] ...
 67-208 1.12e-04

Histone chaperone involved in gene silencing [Transcription / Chromatin structure and dynamics];


Pssm-ID: 227466 [Multi-domain]  Cd Length: 279  Bit Score: 44.60  E-value: 1.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  67 EEGDRDPKNFSDEKNEENEAAtennqvktDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKEKNvKEVGSESD 146
Cdd:COG5137  147 EKPRVTRFNIVWDNDEDNDEA--------PPAQPDVDNEEEERLEESDGREEEEDEEVGSDSYGEGNRELN-EEEEEEAE 217

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 292630954 147 ETTQKEkTQLEEstEENKSEDGNGNEEKAEE---NASETEESTEKSSKEVFPAGDQAEITKESST 208
Cdd:COG5137  218 GSDDGE-DVVDY--EGERIDKKQGEEEEMEEeviNLFEIEWEEESPSEEVPRNNEESPAKKQKVE 279
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 78-192 1.75e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 45.16  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   78 DEKNEEN-EAATENNqVKTDSENSAEGNqVNESSGEKTEagEERKESDDNNGDGDGEK--EKNVKEVGSESDETTQKEkt 154
Cdd:PTZ00341  956 EEDAEENvEENVEEN-VEENVEENVEEN-VEENVEENVE--ENVEENVEENIEENVEEnvEENIEENVEEYDEENVEE-- 1029

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 292630954  155 qLEESTEENKSEDGNGNEEKAEENASET-EESTEKSSKE 192
Cdd:PTZ00341 1030 -VEENVEEYDEENVEEIEENAEENVEENiEENIEEYDEE 1067
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 51-234 2.53e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 44.62  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   51 SSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTdSENSAEGNQVNESSGEKTEAGEERKESD-DNNGD 129
Cdd:COG5271   644 ASEAADEDADAETEAEASADESEEEAEDESETSSEDAEEDADAAA-AEASDDEEETEEADEDAETASEEADAEEaDTEAD 722

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  130 GDGEKEKNVKEVGSESDETTQKEKTQ-----LEESTEENKSEDGNGNEEKAEENASETEEST-----EKSSKEVFPAGDQ 199
Cdd:COG5271   723 GTAEEAEEAAEEAESADEEAASLPDEadaeeEAEEAEEAEEDDADGLEEALEEEKADAEEAAtdeeaEAAAEEKEKVADE 802

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 292630954  200 AEITKESSTGDGAWSTQLVESQNEKKAQQSSISKD 234
Cdd:COG5271   803 DQDTDEDALLDEAEADEEEDLDGEDEETADEALED 837
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
347-463 2.97e-04

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 42.29  E-value: 2.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 347 HYIDFIQQSHPaiawGNRTRVILDVGCGVASFGGYLFER--DVLALSFAPKdeheaQVQFALERGIPAMLNVMGTKRLPF 424
Cdd:COG4976   33 LLAEELLARLP----PGPFGRVLDLGCGTGLLGEALRPRgyRLTGVDLSEE-----MLAKAREKGVYDRLLVADLADLAE 103

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 292630954 425 PGSVFDLIHCarCRVPWHIEGGKLLL-ELNRALRPGGFFV 463
Cdd:COG4976  104 PDGRFDLIVA--ADVLTYLGDLAAVFaGVARALKPGGLFI 141
PRK08317 PRK08317
hypothetical protein; Provisional
 353-460 4.04e-04

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 42.62  E-value: 4.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 353 QQSHPAIAWGNRTRViLDVGCG----VASFGGYLF-ERDVLALsfapkDEHEAQVQFALERGIPAMLNV----MGTKRLP 423
Cdd:PRK08317   9 ARTFELLAVQPGDRV-LDVGCGpgndARELARRVGpEGRVVGI-----DRSEAMLALAKERAAGLGPNVefvrGDADGLP 82

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 292630954 424 FPGSVFDLihCARCRVPWHIEG-GKLLLELNRALRPGG 460
Cdd:PRK08317  83 FPDGSFDA--VRSDRVLQHLEDpARALAEIARVLRPGG 118
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 345-465 5.55e-04

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 42.27  E-value: 5.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  345 ALHYIDFIQQSHPAIawgnrTRVILDVGCGVASFGGYLFER----DVLALSFAPKDEHEA------QVQFalergipaml 414
Cdd:TIGR02072  20 AKRLLALLKEKGIFI-----PASVLDIGCGTGYLTRALLKRfpqaEFIALDISAGMLAQAktklseNVQF---------- 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 292630954  415 nVMG-TKRLPFPGSVFDLIHCARCrVPWHIEGGKLLLELNRALRPGGFFVWS 465
Cdd:TIGR02072  85 -ICGdAEKLPLEDSSFDLIVSNLA-LQWCDDLSQALSELARVLKPGGLLAFS 134
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 62-201 9.24e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 42.69  E-value: 9.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   62 NDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAgeERKESDDNNGDGDG-EKEKNVKE 140
Cdd:COG5271   385 ADEADAAADDSADDEEASADGGTSPTSDTDEEEEEADEDASAGETEDESTDVTSA--EDDIATDEEADSLAdEEEEAEAE 462

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 292630954  141 VGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENasETEESTEKSSKEVFPAGDQAE 201
Cdd:COG5271   463 LDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDA--EAEADSDELTAEETSADDGAD 521
PTZ00121 PTZ00121
MAEBL; Provisional
 56-228 9.59e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 9.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   56 AKDVSKNDLRKEEGDRDPKnfSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKE 135
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKK--ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK 1504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  136 K-NVKEVGSESDETTQKEKT-QLEESTEENKSEDGNGNEE--------KAEE--NASETEESTEKSSKE--VFPAGDQAE 201
Cdd:PTZ00121 1505 AaEAKKKADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEEkkkadelkKAEElkKAEEKKKAEEAKKAEedKNMALRKAE 1584

                         170       180
                  ....*....|....*....|....*..
gi 292630954  202 ITKESSTGDGAWSTQLVESQNEKKAQQ 228
Cdd:PTZ00121 1585 EAKKAEEARIEEVMKLYEEEKKMKAEE 1611
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 53-210 1.32e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 42.31  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   53 TDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQvNESSGEKTEAGEERKESDDNNGDGDG 132
Cdd:COG5271   392 ADDSADDEEASADGGTSPTSDTDEEEEEADEDASAGETEDESTDVTSAEDDIA-TDEEADSLADEEEEAEAELDTEEDTE 470

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  133 EKEKNvkevgSESDETTQKE-------KTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKE 205
Cdd:COG5271   471 SAEED-----ADGDEATDEDdasddgdEEEAEEDAEAEADSDELTAEETSADDGADTDAAADPEDSDEDALEDETEGEEN 545


                  ....*
gi 292630954  206 SSTGD 210
Cdd:COG5271   546 APGSD 550
PTZ00121 PTZ00121
MAEBL; Provisional
 63-191 1.32e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   63 DLRKEEGDRDPKNFSDEKNEENEAATENNQvKTDSENSAEGNQVNESSGEKTEAGEERKESDDnngdgdgEKEKNVKEVG 142
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELK-KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE-------DEKKAAEALK 1695

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 292630954  143 SESDETTQKEKTQLEESTEENKSEDGNGNEE----KAEENASETEESTEKSSK 191
Cdd:PTZ00121 1696 KEAEEAKKAEELKKKEAEEKKKAEELKKAEEenkiKAEEAKKEAEEDKKKAEE 1748
PHA03169 PHA03169
hypothetical protein; Provisional
 65-201 1.36e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 1.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  65 RKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENsaEGNQVNESSGEKTEA--GEERKESDDNNGdGDGEKEKNVKEVG 142
Cdd:PHA03169  30 REQAGRRRGTAARAAKPAPPAPTTSGPQVRAVAEQ--GHRQTESDTETAEESrhGEKEERGQGGPS-GSGSESVGSPTPS 106

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 292630954 143 SESDEttQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAE 201
Cdd:PHA03169 107 PSGSA--EELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQP 163
PTZ00121 PTZ00121
MAEBL; Provisional
 56-205 1.36e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   56 AKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKE 135
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 292630954  136 KNVKEVGSESDETTQK-EKTQLEESTEENKSEDGNGNEE----KAEENASETEESTEKSSKEVFPAGDQAEITKE 205
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKaEELKKAEEENKIKAEEAKKEAEedkkKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
Taf7 COG5414
TATA-binding protein-associated factor Taf7, part of the TFIID transcription initiation ...
 58-184 1.48e-03

TATA-binding protein-associated factor Taf7, part of the TFIID transcription initiation complex [Transcription];


Pssm-ID: 227701  Cd Length: 392  Bit Score: 41.61  E-value: 1.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  58 DVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNqvktdSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKEKN 137
Cdd:COG5414  211 DLLEKDMKAESVSVVLKDEKELARQERVSSWENF-----KEEPGEPLSRPALKKEKQGAEEEGEEGMSEEDLDVGAAEIE 285

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 292630954 138 VKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENaSETEE 184
Cdd:COG5414  286 NKEVSEGDKEQQQEEVENAEAHKEEVQSDRPDEIGEEKEED-DENEE 331
DMP1 pfam07263
Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix ...
 40-236 1.93e-03

Dentin matrix protein 1 (DMP1); This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth specific protein initially identified from mineralized dentin. DMP1 is primarily localized in the nuclear compartment of undifferentiated osteoblasts. In the nucleus, DMP1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the early phase of osteoblast maturation, Ca(2+) surges into the nucleus from the cytoplasm, triggering the phosphorylation of DMP1 by a nuclear isoform of casein kinase II. This phosphorylated DMP1 is then exported out into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP1 is a unique molecule that initiates osteoblast differentiation by transcription in the nucleus and orchestrates mineralized matrix formation extracellularly, at later stages of osteoblast maturation. The DMP1 gene has been found to be ectopically expressed in lung cancer although the reason for this is unknown.


Pssm-ID: 462128 [Multi-domain]  Cd Length: 519  Bit Score: 41.45  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   40 SWSApADSAGYSSTDTAKDVSKNDlrkEEGDRDPKnfSDEKNEENEAATEN-NQVKTDSENSAEG-NQVNESSGEKTEAG 117
Cdd:pfam07263 306 SQSR-EDSKSESQEDSEESQSQED---SQNSQDPS--SESSQEADLPSQESsSESQEEVVSESRGdNPDNTSSSEEDQED 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  118 EERKESDDNNGDGDGEKEKNVKEVGSESDETTqKEKTQLEESTEENKSEdgngneekAEENASETEESTEKSSKEVFPAG 197
Cdd:pfam07263 380 SDSSEEDSLSTFSSSESESREEQADSESNESL-RSSEESPESSEDENSS--------SQEGLQSHSASTESQSEESQSEQ 450

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 292630954  198 D-QAEITKESSTGDGAWStqlVESQNEKKAQQSSISKDQS 236
Cdd:pfam07263 451 DsQSEEDDESDSQDSSRS---KEDSNSTESTSSSEEDGQS 487
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 42-179 3.11e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 40.75  E-value: 3.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  42 SAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERK 121
Cdd:PRK05901  62 MVKDTDDATESDIPKKKTKTAAKAAAAKAPAKKKLKDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDD 141

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 292630954 122 ESDDNNGDGDGEKEKNVKEVGSESDETTQKEKtqlEESTEENKSEDGNGNEEKAEENA 179
Cdd:PRK05901 142 LDDDDIDDDDDDEDDDEDDDDDDVDDEDEEKK---EAKELEKLSDDDDFVWDEDDSEA 196
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 48-196 3.57e-03

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 41.00  E-value: 3.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  48 AGYSSTDTAKDvSKNDLRKEEGDRDPKNFSDEKnEENEAATENNQVKTDSENSAEGNQ-------VNESSGEKTEAGEER 120
Cdd:PTZ00482  81 NQRKSLDDDDD-DEFDFLYEDDEDDAGNATSGE-SSTDDDSLLELPDRDEDADTQANNdqtndfdQDDSSNSQTDQGLKQ 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 121 KESDDNN----GDGDGEKEKNVKEVGSESDETTQKEKTQLEESTE--------ENKSEDGNGNEEKAEENASETEESTEK 188
Cdd:PTZ00482 159 SVNLSSAekliEEKKGQTENTFKFYNFGNDGEEAAAKDGGKSKSSdpgplndsDGQGDDGDPESAEEDKAASNTRAAYTK 238


                 ....*...
gi 292630954 189 SSkEVFPA 196
Cdd:PTZ00482 239 AT-SVFPG 245
PTZ00121 PTZ00121
MAEBL; Provisional
 70-235 6.40e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 6.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954   70 DRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNgdgdgeKEKNVKEVGSESDETT 149
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEN------KIKAAEEAKKAEEDKK 1675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  150 QKEKTQLEESTEENKSEdgngNEEKAEENASETEESTEKSSKEVfpagDQAEITKESSTGDGAWSTQLVESQNEKKAQQS 229
Cdd:PTZ00121 1676 KAEEAKKAEEDEKKAAE----ALKKEAEEAKKAEELKKKEAEEK----KKAEELKKAEEENKIKAEEAKKEAEEDKKKAE 1747


                  ....*.
gi 292630954  230 SISKDQ 235
Cdd:PTZ00121 1748 EAKKDE 1753
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
366-463 8.44e-03

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 36.34  E-value: 8.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 366 RVILDVGCGVASFGGYLFER----DVLALsfapkDEHEAQVQFALERGIPAMLNVMGTKRLPFPGSvFDLIHCArcRVPW 441
Cdd:COG4106    3 RRVLDLGCGTGRLTALLAERfpgaRVTGV-----DLSPEMLARARARLPNVRFVVADLRDLDPPEP-FDLVVSN--AALH 74

                         90       100
                 ....*....|....*....|...
gi 292630954 442 HIEG-GKLLLELNRALRPGGFFV 463
Cdd:COG4106   75 WLPDhAALLARLAAALAPGGVLA 97
COG5644 COG5644
U3 small nucleolar RNA-associated protein 14 [Function unknown];
37-208 8.64e-03

U3 small nucleolar RNA-associated protein 14 [Function unknown];


Pssm-ID: 227931 [Multi-domain]  Cd Length: 869  Bit Score: 39.69  E-value: 8.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954  37 FMSSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQvkTDSENSAEGNQVNESsgeKTEA 116
Cdd:COG5644   31 FDSEELEDNDEQGYSFGVNSEDDEEIDSDEAFDEEDEKRFADWSFNASKSGKSNKD--HKNLNNTKEISLNDS---DDSV 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 292630954 117 GEERKESDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPA 196
Cdd:COG5644  106 NSDKLENEGSVSSIDENELVDLDTLLDNDQPEKNESGNNDHATDKENLLESDASSSNDSESEESDSESEIESSDSDHDDE 185

                        170
                 ....*....|..
gi 292630954 197 GDQAEITKESST 208
Cdd:COG5644  186 NSDSKLDNLRNY 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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