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Conserved domains on  [gi|1372873189|gb|PSZ14091|]
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flagellar protein FliT [Escherichia coli]

Protein Classification

flagella biosynthesis regulatory protein FliT( domain architecture ID 10013558)

flagella biosynthesis regulatory protein FliT is a dual-function protein that regulates the transcription of class 2 flagellar operons and also acts as an export chaperone for the filament-capping protein FliD

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10548 PRK10548
flagella biosynthesis regulatory protein FliT;
1-121 6.65e-53

flagella biosynthesis regulatory protein FliT;


:

Pssm-ID: 182538  Cd Length: 121  Bit Score: 162.08  E-value: 6.65e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372873189   1 MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQIRPMLRLILDNESKVKQ 80
Cdd:PRK10548    1 MNNAPHLLSAWQQILTLSQSMLRLATEGQWDELIEQEVAYVQAVEEIAHLTIPPDISTVMQEQLRPMLRQILDNEAELKQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1372873189  81 LLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF 121
Cdd:PRK10548   81 LLQQRMDELSSLIGQSTRQKSVNSAYGQLSGFVLLPDEPLF 121
 
Name Accession Description Interval E-value
PRK10548 PRK10548
flagella biosynthesis regulatory protein FliT;
1-121 6.65e-53

flagella biosynthesis regulatory protein FliT;


Pssm-ID: 182538  Cd Length: 121  Bit Score: 162.08  E-value: 6.65e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372873189   1 MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQIRPMLRLILDNESKVKQ 80
Cdd:PRK10548    1 MNNAPHLLSAWQQILTLSQSMLRLATEGQWDELIEQEVAYVQAVEEIAHLTIPPDISTVMQEQLRPMLRQILDNEAELKQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1372873189  81 LLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF 121
Cdd:PRK10548   81 LLQQRMDELSSLIGQSTRQKSVNSAYGQLSGFVLLPDEPLF 121
FliT pfam05400
Flagellar protein FliT; This family contains several bacterial flagellar FliT proteins. The ...
 21-106 8.16e-19

Flagellar protein FliT; This family contains several bacterial flagellar FliT proteins. The flagellar proteins FlgN and FliT have been proposed to act as substrate specific export chaperones, facilitating incorporation of the enterobacterial hook-associated axial proteins (HAPs) FlgK/FlgL and FliD into the growing flagellum. In Salmonella typhimurium flgN and fliT mutants, the export of target HAPs is reduced, concomitant with loss of unincorporated flagellin into the surrounding medium.


Pssm-ID: 461640  Cd Length: 86  Bit Score: 74.67  E-value: 8.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372873189  21 MLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQIRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQK 100
Cdd:pfam05400   1 MLEAARAGDWDELVALEAERQQLVERLRELEPEAPLSDAERAEKRELLRRILENDAEIRALLQPRLDELQKLLGQARRQR 80


                  ....*.
gi 1372873189 101 SVLSAY 106
Cdd:pfam05400  81 KANNAY 86
 
Name Accession Description Interval E-value
PRK10548 PRK10548
flagella biosynthesis regulatory protein FliT;
1-121 6.65e-53

flagella biosynthesis regulatory protein FliT;


Pssm-ID: 182538  Cd Length: 121  Bit Score: 162.08  E-value: 6.65e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372873189   1 MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQIRPMLRLILDNESKVKQ 80
Cdd:PRK10548    1 MNNAPHLLSAWQQILTLSQSMLRLATEGQWDELIEQEVAYVQAVEEIAHLTIPPDISTVMQEQLRPMLRQILDNEAELKQ 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1372873189  81 LLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF 121
Cdd:PRK10548   81 LLQQRMDELSSLIGQSTRQKSVNSAYGQLSGFVLLPDEPLF 121
FliT pfam05400
Flagellar protein FliT; This family contains several bacterial flagellar FliT proteins. The ...
 21-106 8.16e-19

Flagellar protein FliT; This family contains several bacterial flagellar FliT proteins. The flagellar proteins FlgN and FliT have been proposed to act as substrate specific export chaperones, facilitating incorporation of the enterobacterial hook-associated axial proteins (HAPs) FlgK/FlgL and FliD into the growing flagellum. In Salmonella typhimurium flgN and fliT mutants, the export of target HAPs is reduced, concomitant with loss of unincorporated flagellin into the surrounding medium.


Pssm-ID: 461640  Cd Length: 86  Bit Score: 74.67  E-value: 8.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372873189  21 MLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQIRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQK 100
Cdd:pfam05400   1 MLEAARAGDWDELVALEAERQQLVERLRELEPEAPLSDAERAEKRELLRRILENDAEIRALLQPRLDELQKLLGQARRQR 80


                  ....*.
gi 1372873189 101 SVLSAY 106
Cdd:pfam05400  81 KANNAY 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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